#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P97414	uniprotkb:P11499	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8BSY0	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8366490|uniprotkb:Q9EQ64|intact:MINT-4112262|uniprotkb:Q9EPA6|uniprotkb:Q6P8S1|ensembl:ENSMUSP00000077273	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:asph_mouse(display_long)|uniprotkb:Asph(gene name)|psi-mi:Asph(display_short)|uniprotkb:Aspartate beta-hydroxylase(gene name synonym)|uniprotkb:Peptide-aspartate beta-dioxygenase(gene name synonym)|uniprotkb:Bah(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001171327.1|refseq:NP_001171323.1|refseq:NP_001171326.1|refseq:NP_001171325.1|refseq:NP_001171321.1|refseq:NP_075553.2|refseq:NP_001171324.1|refseq:NP_001277296.1|ensembl:ENSMUSG00000028207(gene)|ensembl:ENSMUST00000078139(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0007389"(pattern specification process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033198"(response to ATP)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0062101"(peptidyl-aspartic acid 3-dioxygenase activity)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|go:"GO:1901879"(regulation of protein depolymerization)|interpro:IPR007803(Aspartyl/Asparaginyl beta-hydroxylase)|interpro:IPR007943(Aspartyl beta-hydroxylase, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027443|interpro:IPR039038|mint:Q8BSY0|reactome:R-MMU-2672351|reactome:R-MMU-5578775|go:"GO:0045862"(positive regulation of proteolysis)	-	-	comment:mint|function:"Specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins"	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:x06lMmMmxgaETSn5iGJ/1hScfSI10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P50544	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8345582|intact:MINT-1860557|uniprotkb:O35289|uniprotkb:O55133|ensembl:ENSMUSP00000099634	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:acadv_mouse(display_long)|uniprotkb:Acadvl(gene name)|psi-mi:Acadvl(display_short)|uniprotkb:Vlcad(gene name synonym)|uniprotkb:MVLCAD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_059062.1|ensembl:ENSMUSG00000018574(gene)|ensembl:ENSMUST00000102574(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0090181"(regulation of cholesterol metabolic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:P50544|reactome:R-MMU-77305	-	-	comment:mint|function:Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:4AfQt7R5VKSc3Q4cAyT1Iaknyoc10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P47934	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8346602|uniprotkb:Q923A6|uniprotkb:Q3TCG3|intact:MINT-4089666|uniprotkb:Q3V1Y3|ensembl:ENSMUSP00000028207|ensembl:ENSMUSP00000099919	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:cacp_mouse(display_long)|uniprotkb:Crat(gene name)|psi-mi:Crat(display_short)|uniprotkb:Carnitine acetyltransferase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_031786.2|ensembl:ENSMUSG00000026853(gene)|ensembl:ENSMUST00000028207(transcript)|ensembl:ENSMUST00000102855(transcript)|go:"GO:0003997"(acyl-CoA oxidase activity)|go:"GO:0004092"(carnitine O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008458"(carnitine O-octanoyltransferase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0046459"(short-chain fatty acid metabolic process)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042231|mint:P47934|rcsb pdb:1NDB|rcsb pdb:1NDF|rcsb pdb:1NDI|rcsb pdb:1T7N|rcsb pdb:1T7O|rcsb pdb:1T7Q|rcsb pdb:2H3P|rcsb pdb:2H3U|rcsb pdb:2H3W|reactome:R-MMU-389887|reactome:R-MMU-9033241	-	-	function:Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria|comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:0M/qKmIjnQiSzBdagoRdKY3SE8A10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P19783	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-7174084|ensembl:ENSMUSP00000034276|ensembl:ENSMUSP00000138019|uniprotkb:Q545A9|intact:MINT-1860013	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:cox41_mouse(display_long)|uniprotkb:Cox4i1(gene name)|psi-mi:Cox4i1(display_short)|uniprotkb:Cox4(gene name synonym)|uniprotkb:Cox4a(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001280488.1|refseq:NP_034071.2|ensembl:ENSMUSG00000031818(gene)|ensembl:ENSMUST00000034276(transcript)|ensembl:ENSMUST00000181586(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P19783|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564	-	-	function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport|comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:zt2qwV/jVAo1B9UISW8R2votzlU10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P04919	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8350852|intact:MINT-1861446|ensembl:ENSMUSP00000006749	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:b3at_mouse(display_long)|uniprotkb:Slc4a1(gene name)|psi-mi:Slc4a1(display_short)|uniprotkb:Ae1(gene name synonym)|uniprotkb:Anion exchange protein 1(gene name synonym)|uniprotkb:Solute carrier family 4 member 1(gene name synonym)|uniprotkb:MEB3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_035533.1|ensembl:ENSMUSG00000006574(gene)|ensembl:ENSMUST00000006749(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0007596"(blood coagulation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010037"(response to carbon dioxide)|go:"GO:0014704"(intercalated disc)|go:"GO:0014823"(response to activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0019899"(enzyme binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030018"(Z disc)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045852"(pH elevation)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904539"(negative regulation of glycolytic process through fructose-6-phosphate)|interpro:IPR001717(Anion exchange protein)|interpro:IPR002977(Anion exchange protein 1)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR018241|mint:P04919|reactome:R-MMU-1237044|reactome:R-MMU-1247673|reactome:R-MMU-425381	-	-	comment:mint|function:"Band 3 is the major integral glycoprotein of the erythrocyte membrane. Band 3 has two functional domains. Its integral domain mediates a 1:1 exchange of inorganic anions across the membrane, whereas its cytoplasmic domain provides binding sites for cytoskeletal proteins, glycolytic enzymes, and hemoglobin"	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:Qq0Xf0faIrE7Mqa++JNT5ryYNYc10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q04857	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8345547|intact:MINT-4091372|ensembl:ENSMUSP00000001147	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:co6a1_mouse(display_long)|uniprotkb:Col6a1(gene name)|psi-mi:Col6a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_034063.1|ensembl:ENSMUSG00000001119(gene)|ensembl:ENSMUST00000001147(transcript)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042383"(sarcolemma)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036465|mint:Q04857|reactome:R-MMU-1442490|reactome:R-MMU-1650814|reactome:R-MMU-186797|reactome:R-MMU-2022090|reactome:R-MMU-216083|reactome:R-MMU-3000178|reactome:R-MMU-419037|reactome:R-MMU-8948216	-	-	comment:mint|function:Collagen VI acts as a cell-binding protein	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:kM8Xi8xfLOEcDb2NpFlknxpak8U10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9QVP4	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8357276|uniprotkb:Q9JIE8|intact:MINT-4102168|uniprotkb:Q63977|ensembl:ENSMUSP00000099985	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:mlra_mouse(display_long)|uniprotkb:Myl7(gene name)|psi-mi:Myl7(display_short)|uniprotkb:Mylc2a(gene name synonym)|uniprotkb:Myosin regulatory light chain 7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_075017.2|ensembl:ENSMUSG00000020469(gene)|ensembl:ENSMUST00000102921(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0031672"(A band)|go:"GO:0043197"(dendritic spine)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9QVP4|reactome:R-MMU-445355	-	-	comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:leuWAVQCkKG0daoyT4BpClk7lyc10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P35980	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-7977881|uniprotkb:Q9D987|intact:MINT-1857698|uniprotkb:Q9CQF1|ensembl:ENSMUSP00000072320|ensembl:ENSMUSP00000147816	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rl18_mouse(display_long)|uniprotkb:Rpl18(gene name)|psi-mi:Rpl18(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_033103.2|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR000039(Ribosomal protein L18e)|interpro:IPR021131|interpro:IPR021132|interpro:IPR036227|mint:P35980|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|ensembl:ENSMUSG00000059070(gene)|ensembl:ENSMUST00000072503(transcript)|ensembl:ENSMUST00000210640(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|reactome:R-MMU-975957	-	-	comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:PqTr3iXlemHDle24HNyRs+yPRJg10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q5SW19	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8315491|intact:UNK-5482502|intact:MINT-4115908|uniprotkb:Q3U4M5|uniprotkb:Q3V3Q8|intact:UNK-5408909|uniprotkb:Q505Q6|uniprotkb:Q6PAT1|uniprotkb:Q8CHD9|uniprotkb:Q6GQX1|uniprotkb:Q3U014|intact:UNK-5473899|intact:UNK-5429492|uniprotkb:A8Y5E2	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:clu_mouse(display_long)|uniprotkb:Cluh(gene name)|psi-mi:Cluh(display_short)|uniprotkb:Kiaa0664(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR033646|interpro:IPR025697|refseq:NP_001074627.1|interpro:IPR027523|interpro:IPR028275|refseq:XP_006534416.1|refseq:XP_006534417.1|mint:Q5SW19|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023231	-	-	comment:"fragmentation type: fragment"|comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:hyZPFP7G2ri2LuDUtQ2FgZwOggA10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P62267	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8313545|ensembl:ENSMUSP00000054490|uniprotkb:P39028|uniprotkb:Q542K7|intact:MINT-1857177	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rs23_mouse(display_long)|uniprotkb:Rps23(gene name)|psi-mi:Rps23(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000049517(gene)|ensembl:ENSMUST00000051955(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR005680(Ribosomal protein S23, eukaryotic/archaeal)|interpro:IPR006032(Ribosomal protein S12/S23)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P62267|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_077137.1	-	-	comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:MWZPvSL/G45ocaxA5AXKCkDQxNU10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:O08528	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8344432|intact:MINT-262872|ensembl:ENSMUSP00000000642	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:hxk2_mouse(display_long)|uniprotkb:Hk2(gene name)|psi-mi:Hk2(display_short)|uniprotkb:Hexokinase type II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_038848.1|dip:DIP-41484N|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:O08528|reactome:R-MMU-70171|ensembl:ENSMUSG00000000628(gene)|ensembl:ENSMUST00000000642(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007595"(lactation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008865"(fructokinase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019158"(mannokinase activity)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001312(Hexokinase)	-	-	comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:Gm80aqf9jxkgIUOQFjicRMUq2wE10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:O88492	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8347295|uniprotkb:Q69Z80|uniprotkb:E9QN72|intact:MINT-4105562|uniprotkb:Q8BNV5|ensembl:ENSMUSP00000002908|ensembl:ENSMUSP00000139859	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:plin4_mouse(display_long)|uniprotkb:Kiaa1881(gene name synonym)|uniprotkb:Adipocyte protein S3-12(gene name synonym)|uniprotkb:Plin4(gene name)|psi-mi:Plin4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_065593.2|ensembl:ENSMUSG00000002831(gene)|ensembl:ENSMUST00000002908(transcript)|ensembl:ENSMUST00000190703(transcript)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR004279(Perilipin)|mint:O88492	-	-	comment:mint|function:May play a role in triacylglycerol packaging into adipocytes. May function as a coat protein involved in the biogenesis of lipid droplets	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:VIrsWg+3qqLWYOcp+l6NNgXcG2M10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:O08739	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8419036|uniprotkb:O88692|intact:MINT-4115626|uniprotkb:Q8CFR4|ensembl:ENSMUSP00000005829|ensembl:ENSMUSP00000130495	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ampd3_mouse(display_long)|uniprotkb:Ampd3(gene name)|psi-mi:Ampd3(display_short)|uniprotkb:AMP deaminase H-type(gene name synonym)|uniprotkb:AMP deaminase isoform E(gene name synonym)|uniprotkb:Heart-type AMPD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001263230.1|refseq:NP_033797.2|refseq:XP_006507285.1|refseq:XP_006507282.1|ensembl:ENSMUSG00000005686(gene)|ensembl:ENSMUST00000005829(transcript)|ensembl:ENSMUST00000170374(transcript)|go:"GO:0003876"(AMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006188"(IMP biosynthetic process)|go:"GO:0006196"(AMP catabolic process)|go:"GO:0032264"(IMP salvage)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046032"(ADP catabolic process)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0097009"(energy homeostasis)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006329(AMP deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR029771|interpro:IPR032466|mint:O08739|reactome:R-MMU-6798695|reactome:R-MMU-74217	-	-	comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:4oCNKt08UPpybp4POUcQGhLds3g10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9D172	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8321099|intact:MINT-1841972|ensembl:ENSMUSP00000001242	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:gal3a_mouse(display_long)|uniprotkb:Gatd3(gene name)|psi-mi:Gatd3(display_short)|uniprotkb:D10Jhu81e(gene name synonym)|uniprotkb:Gatd3a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_613067.1|ensembl:ENSMUSG00000053329(gene)|ensembl:ENSMUST00000001242(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR029062|mint:Q9D172	-	-	comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:yaWG8Dudv7cOIDqG+5bFSWgJ5+810090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q99NB1	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8346875|intact:MINT-4086737|uniprotkb:Q8K0M6|ensembl:ENSMUSP00000028944	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:acs2l_mouse(display_long)|uniprotkb:Acss1(gene name)|psi-mi:Acss1(display_short)|uniprotkb:Acas2(gene name synonym)|uniprotkb:Acas2l(gene name synonym)|uniprotkb:Acetate--CoA ligase 2(gene name synonym)|uniprotkb:Acetyl-CoA synthetase 2(gene name synonym)|uniprotkb:Acyl-CoA synthetase short-chain family member 1(gene name synonym)|uniprotkb:Propionate--CoA ligase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_542142.1|dip:DIP-61209N|ensembl:ENSMUSG00000027452(gene)|ensembl:ENSMUST00000028944(transcript)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0019413"(acetate biosynthetic process)|go:"GO:0019427"(acetyl-CoA biosynthetic process from acetate)|go:"GO:0019542"(propionate biosynthetic process)|go:"GO:0050218"(propionate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011904(Acetate--CoA ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR032387|interpro:IPR042099|mint:Q99NB1|reactome:R-MMU-71384	-	-	function:"Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2)"|comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:h3dcddwI6x6n1h9/eQAdHaNuIMA10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P45952	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8344397|uniprotkb:Q64235|intact:MINT-1860219|ensembl:ENSMUSP00000072483	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:acadm_mouse(display_long)|uniprotkb:Acadm(gene name)|psi-mi:Acadm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_031408.1|ensembl:ENSMUSG00000062908(gene)|ensembl:ENSMUST00000072697(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001889"(liver development)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007507"(heart development)|go:"GO:0009409"(response to cold)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016853"(isomerase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0030424"(axon)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|mint:P45952|reactome:R-MMU-77288|reactome:R-MMU-77346|reactome:R-MMU-77348	-	-	function:This enzyme is specific for acyl chain lengths of 4 to 16|comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:Zfgo1s6CGy4mfJ3L1T7CHc6vQd810090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P51174	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8345212|uniprotkb:O35302|uniprotkb:Q9CU29|uniprotkb:Q9DB83|uniprotkb:B2KGC6|intact:MINT-1861818|uniprotkb:Q8QZR6	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:acadl_mouse(display_long)|uniprotkb:Acadl(gene name)|psi-mi:Acadl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|refseq:NP_031407.2|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR034179|interpro:IPR036250|interpro:IPR037069|mint:P51174|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0016401"(palmitoyl-CoA oxidase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042413"(carnitine catabolic process)|go:"GO:0042758"(long-chain fatty acid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|reactome:R-MMU-77285|reactome:R-MMU-77310|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)	-	-	comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:AhEJczI8Mvr0mAx2w1u+QFZ+fWA10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:O55124	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8344336|intact:MINT-4105158	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:o55124_mouse(display_long)|uniprotkb:Myom2(gene name)|psi-mi:Myom2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_032690.2|mint:O55124|interpro:IPR036116|interpro:IPR036179|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)	-	-	comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:flGHrJLFPy45TlRjGR1w+o9tEuY10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q91W39	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8329509|uniprotkb:A2A5L2|intact:MINT-4103204|ensembl:ENSMUSP00000046388	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ncoa5_mouse(display_long)|uniprotkb:Ncoa5(gene name)|psi-mi:Ncoa5(display_short)|uniprotkb:Coactivator independent of AF-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_659141.1|ensembl:ENSMUSG00000039804(gene)|ensembl:ENSMUST00000040381(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|interpro:IPR036621|mint:Q91W39	-	-	comment:mint|function:"Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC/c-myc in response to 17-beta-estradiol (E2)"	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:wPwJKZRExN0LsGR8FyKm74oUm2g10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9DBZ5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-7466644|uniprotkb:Q8K3A1|uniprotkb:Q58EU9|intact:MINT-4098437|ensembl:ENSMUSP00000066038	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3k_mouse(display_long)|uniprotkb:Eif3k(gene name)|psi-mi:Eif3k(display_short)|uniprotkb:Eif3s12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001272871.1|refseq:NP_082935.1|ensembl:ENSMUSG00000053565(gene)|ensembl:ENSMUST00000066070(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9DBZ5|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:6inN9+78GHgwKiXC/s5lDjTbKsw10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9QZD9	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-7466616|intact:MINT-1869798|ensembl:ENSMUSP00000099653	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3i_mouse(display_long)|uniprotkb:Eif3i(gene name)|psi-mi:Eif3i(display_short)|uniprotkb:Trip1(gene name synonym)|uniprotkb:Eif3s2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_061269.1|ensembl:ENSMUSG00000028798(gene)|ensembl:ENSMUST00000102593(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q9QZD9|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:R7AzLvRTsjnmue48odsUwRAUIsM10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q99JX4	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8312665|ensembl:ENSMUSP00000028592|intact:MINT-1869888|uniprotkb:Q5EBI5|uniprotkb:Q3TI04	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3m_mouse(display_long)|uniprotkb:Pcid1(gene name synonym)|uniprotkb:Eif3m(gene name)|psi-mi:Eif3m(display_short)|uniprotkb:PCI domain-containing protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	reactome:R-MMU-72706|reactome:R-MMU-72702|ensembl:ENSMUSG00000027170(gene)|ensembl:ENSMUST00000028592(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006412"(translation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027528|interpro:IPR036390|interpro:IPR040750|mint:Q99JX4|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|refseq:NP_663355.1|dip:DIP-59784N	-	-	function:Component of the eIF-3 complex, which binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:b2PpL8mxfJDS47A/ZSr163bG4dg10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q6NZJ6	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8175606|uniprotkb:Q6NZN8|uniprotkb:Q8BW99|intact:MINT-1856450|ensembl:ENSMUSP00000047678|ensembl:ENSMUSP00000111120	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:if4g1_mouse(display_long)|uniprotkb:Eif4g1(gene name)|psi-mi:Eif4g1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001291361.1|refseq:NP_666053.2|refseq:XP_006522000.1|dip:DIP-42771N|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098794"(postsynapse)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|reactome:R-MMU-975957|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q6NZJ6|reactome:R-MMU-1169408|reactome:R-MMU-156827|reactome:R-MMU-166208|reactome:R-MMU-429947|reactome:R-MMU-450408|reactome:R-MMU-72649|reactome:R-MMU-72662|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|ensembl:ENSMUSG00000045983(gene)|ensembl:ENSMUST00000044783(transcript)|ensembl:ENSMUST00000115460(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)	-	-	comment:mint|function:Component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:91tJB28zzWTM77Jg0kZ18KIUhmo10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8R1B4	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-7466674|uniprotkb:Q8R3M7|intact:MINT-4608642|ensembl:ENSMUSP00000032992	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3c_mouse(display_long)|uniprotkb:Eif3c(gene name)|psi-mi:Eif3c(display_short)|uniprotkb:Eif3s8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_666312.1|ensembl:ENSMUSG00000030738(gene)|ensembl:ENSMUST00000032992(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q8R1B4|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:t9Y/py75bSvLshPOxGcfrNASqeI10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q91WK2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-7466721|intact:MINT-4098428|ensembl:ENSMUSP00000022925	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3h_mouse(display_long)|uniprotkb:Eif3h(gene name)|psi-mi:Eif3h(display_short)|uniprotkb:Eif3s3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_542366.1|ensembl:ENSMUSG00000022312(gene)|ensembl:ENSMUST00000022925(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:Q91WK2|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	comment:mint|function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. Associates with the p170 subunit of EIF3	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:mKyE784VSiEMqBaCyG2Vt9FhynM10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8QZY1	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-7770074|ensembl:ENSMUSP00000038839|intact:MINT-249281|uniprotkb:Q3THF8|uniprotkb:Q91YE4|uniprotkb:Q3TJ04	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3l_mouse(display_long)|uniprotkb:Eif3l(gene name)|psi-mi:Eif3l(display_short)|uniprotkb:Eif3eip(gene name synonym)|uniprotkb:Eif3s6ip(gene name synonym)|uniprotkb:Paf67(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit E-interacting protein(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6-interacting protein(gene name synonym)|uniprotkb:67 kDa polymerase-associated factor(gene name synonym)|uniprotkb:PAF67(gene name synonym)|uniprotkb:66 kDa tyrosine-rich heat shock protein(gene name synonym)|uniprotkb:HSP-66Y(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000033047(gene)|ensembl:ENSMUST00000040518(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019382|mint:Q8QZY1|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|refseq:NP_660121.2	-	-	comment:mint	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:EFn/tQ3iRCMEDBdNQ71CDhC8nQ010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q62234	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8344887|intact:UNK-5482362|uniprotkb:Q6PAC0|intact:MINT-4102904|uniprotkb:Q546T8|ensembl:ENSMUSP00000072945	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:myom1_mouse(display_long)|uniprotkb:Myom1(gene name)|psi-mi:Myom1(display_short)|uniprotkb:Myomesin family member 1(gene name synonym)|uniprotkb:Skelemin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_034997.2|refseq:NP_001077403.1|ensembl:ENSMUSG00000024049(gene)|ensembl:ENSMUST00000073211(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:Q62234|rcsb pdb:2JTD|rcsb pdb:4V10	-	-	comment:mint|function:May link the intermediate filament cytoskeleton to the M-disc of the myofibrils in striated muscle. May also contact myosin filaments. Also binds beta-integrins	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:sfJeAhoFhpjW9v1ci8pVYx2k30410090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q7TPM1	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-16728307|ensembl:ENSMUSP00000035734|uniprotkb:A2AN31|uniprotkb:Q8C755	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:prc2b_mouse(display_long)|uniprotkb:HLA-B-associated transcript 2-like 1(gene name synonym)|uniprotkb:Proline-rich coiled-coil protein 2B(gene name synonym)|uniprotkb:Prrc2b(gene name)|psi-mi:Prrc2b(display_short)|uniprotkb:Bat2l(gene name synonym)|uniprotkb:Bat2l1(gene name synonym)|uniprotkb:Kiaa0515(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000039262(gene)|ensembl:ENSMUST00000036691(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:Q7TPM1|refseq:NP_001153106.1|refseq:NP_766249.2	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:WlCA3MFhuVeSWOib983JRtCgwRI10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P11531	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P05201	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-494448|intact:EBI-2308970|uniprotkb:Q3UJH8|ensembl:ENSMUSP00000026196	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:aatc_mouse(display_long)|uniprotkb:Transaminase A(gene name synonym)|uniprotkb:Glutamate oxaloacetate transaminase 1(gene name synonym)|uniprotkb:Cysteine aminotransferase, cytoplasmic(gene name synonym)|uniprotkb:Cysteine transaminase, cytoplasmic(gene name synonym)|uniprotkb:Got1(gene name)|psi-mi:Got1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_034454.2|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0004609"(phosphatidylserine decarboxylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006114"(glycerol biosynthetic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0019550"(glutamate catabolic process to aspartate)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|go:"GO:0030170"(pyridoxal phosphate binding)|ensembl:ENSMUSG00000025190(gene)|ensembl:ENSMUST00000026196(transcript)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0043679"(axon terminus)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0047801"(L-cysteine transaminase activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060290"(transdifferentiation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:1990267"(response to transition metal nanoparticle)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P05201|reactome:R-MMU-70263|reactome:R-MMU-8963693	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:4if14ijxqySSUHcJ2S2EXDyBzZQ10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P26039	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-1039593|uniprotkb:Q8VEF0|uniprotkb:A2AIM8|ensembl:ENSMUSP00000030187	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:tln1_mouse(display_long)|uniprotkb:Tln1(gene name)|psi-mi:Tln1(display_short)|uniprotkb:Tln(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_035732.2|refseq:XP_006537832.2|ensembl:ENSMUSG00000028465(gene)|ensembl:ENSMUST00000030187(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:P26039|rcsb pdb:1SJ7|rcsb pdb:1SJ8|rcsb pdb:1T01|rcsb pdb:1U89|rcsb pdb:1XWX|rcsb pdb:1Y19|rcsb pdb:1ZW3|rcsb pdb:2B0H|rcsb pdb:2G35|rcsb pdb:2JSW|rcsb pdb:2KBB|rcsb pdb:2KC1|rcsb pdb:2KC2|rcsb pdb:2KGX|rcsb pdb:2KMA|rcsb pdb:2KVP|rcsb pdb:2L10|rcsb pdb:2L7A|rcsb pdb:2L7N|rcsb pdb:2LQG|rcsb pdb:2QDQ|rcsb pdb:2X0C|rcsb pdb:3DYJ|rcsb pdb:3IVF|rcsb pdb:3S90|rcsb pdb:4F7G|rcsb pdb:4W8P|rcsb pdb:5FZT|rcsb pdb:5IC0|rcsb pdb:5IC1|rcsb pdb:5NL1|rcsb pdb:6BA6|rcsb pdb:6MFS|rcsb pdb:6TWN|rcsb pdb:6VGU|reactome:R-MMU-114608|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-399955|reactome:R-MMU-445355|reactome:R-MMU-5674135|dip:DIP-647N	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:w9NQrwqUcuVAzeesymnTmhrEtCk10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8BTM8	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-641991|uniprotkb:B7FAV0|uniprotkb:O54934|uniprotkb:Q7TQI1|uniprotkb:Q8BLK1|uniprotkb:Q8BTN7|uniprotkb:Q8VHX5|uniprotkb:Q8VHX8|uniprotkb:Q99KQ2|ensembl:ENSMUSP00000033699	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:flna_mouse(display_long)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:Flna(gene name)|psi-mi:Flna(display_short)|uniprotkb:Fln(gene name synonym)|uniprotkb:Fln1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:XP_006527974.1|ensembl:ENSMUST00000033699(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|ensembl:ENSMUSG00000031328(gene)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0097368"(establishment of Sertoli cell barrier)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q8BTM8|reactome:R-MMU-114608|reactome:R-MMU-430116|reactome:R-MMU-446353|reactome:R-MMU-5627123	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:hp3whHs7nFMTtChpQ/KywkPalq810090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8BWT1	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-1634016|uniprotkb:Q8JZR8|intact:EBI-4285676|uniprotkb:Q3TIT9|ensembl:ENSMUSP00000037348	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:thim_mouse(display_long)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acaa2(gene name)|psi-mi:Acaa2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_803421.1|ensembl:ENSMUSG00000036880(gene)|ensembl:ENSMUST00000041053(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q8BWT1|reactome:R-MMU-77289	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:15aWO97WJBNGYD449bAgjVjkgTY10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9WUM5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-773740|uniprotkb:Q8C2C3|uniprotkb:Q9DBA3|uniprotkb:Q9DCI8|ensembl:ENSMUSP00000065113	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:suca_mouse(display_long)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym)|uniprotkb:Suclg1(gene name)|psi-mi:Suclg1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_063932.2|ensembl:ENSMUSG00000052738(gene)|ensembl:ENSMUST00000064740(transcript)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|go:"GO:0019003"(GDP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR033847|interpro:IPR036291|mint:Q9WUM5|reactome:R-MMU-71403	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:Bb1b4P5dXlGyek/f6p8+X0Dbzt010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q91WD5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-772751|uniprotkb:Q3U5Y9|uniprotkb:Q3UJX7|uniprotkb:Q99L23|uniprotkb:Q3TNA8|ensembl:ENSMUSP00000013737	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ndus2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)|uniprotkb:Ndufs2(gene name)|psi-mi:Ndufs2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_694704.1|ensembl:ENSMUSG00000013593(gene)|ensembl:ENSMUST00000013737(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:Q91WD5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:dk8e26C1hIdTZvDnX5nE1n+juwk10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9DCT2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-772758|uniprotkb:Q8BTZ3|uniprotkb:Q8R073|ensembl:ENSMUSP00000005647	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ndus3_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym)|uniprotkb:Ndufs3(gene name)|psi-mi:Ndufs3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_080964.1|dip:DIP-32378N|ensembl:ENSMUSG00000005510(gene)|ensembl:ENSMUST00000005647(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016604"(nuclear body)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:Q9DCT2|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|reactome:R-MMU-9013408	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:2tQasToTy6/l6HeQwM+hTVH2Mow10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q60930	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-444578|ensembl:ENSMUSP00000022293|uniprotkb:Q78MH6|uniprotkb:Q99L98	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:vdac2_mouse(display_long)|uniprotkb:Voltage-dependent anion-selective channel protein 6(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)|uniprotkb:Vdac2(gene name)|psi-mi:Vdac2(display_short)|uniprotkb:Vdac6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_035825.1|ensembl:ENSMUSG00000021771(gene)|ensembl:ENSMUST00000022293(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:Q60930|reactome:R-MMU-5689880	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:ApSD4TVlagQ1QHePbOZw7J5rmzQ10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9DB77	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-773760|uniprotkb:Q8BK11|uniprotkb:Q9CVK7|ensembl:ENSMUSP00000033176	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:qcr2_mouse(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:Uqcrc2(gene name)|psi-mi:Uqcrc2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_080175.1|ensembl:ENSMUSG00000030884(gene)|ensembl:ENSMUST00000033176(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006508"(proteolysis)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:Q9DB77|reactome:R-MMU-611105	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:CTpkPoAK0EWa6sxA5LJY0srVn/s10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q6ZQ73	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-6504831|ensembl:ENSMUSP00000075377|uniprotkb:Q6PHT7	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:cand2_mouse(display_long)|uniprotkb:Cand2(gene name)|psi-mi:Cand2(display_short)|uniprotkb:Kiaa0667(gene name synonym)|uniprotkb:Tip120b(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000030319(gene)|ensembl:ENSMUST00000075995(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|refseq:NP_080234.2	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:OkTwdfaLvWK+edxRZnob8ShssWI10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P14148	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-445010|uniprotkb:Q80UR0|ensembl:ENSMUSP00000071616	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rl7_mouse(display_long)|uniprotkb:Rpl7(gene name)|psi-mi:Rpl7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_035421.2|ensembl:ENSMUSG00000043716(gene)|ensembl:ENSMUST00000058437(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P14148|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:3mgKWwOhV0qZfTQwfsTkqol4iIY10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P14094	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-770851|ensembl:ENSMUSP00000027863	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9EQU5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-1543689|uniprotkb:Q9CY82|uniprotkb:Q9D0A9|uniprotkb:Q9Z181|uniprotkb:A2BE95|ensembl:ENSMUSP00000099930	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:set_mouse(display_long)|uniprotkb:Set(gene name)|psi-mi:Set(display_short)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001191804.1|refseq:NP_076360.1|ensembl:ENSMUSG00000054766(gene)|ensembl:ENSMUST00000102866(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9EQU5|reactome:R-MMU-2299718|reactome:R-MMU-450520	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:1PEoqWcGzQ6q4T2SbfswpNI2Dr810090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9CQA3	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-432494|uniprotkb:Q3TF82|uniprotkb:Q9DC91|ensembl:ENSMUSP00000010007	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:sdhb_mouse(display_long)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)|uniprotkb:Sdhb(gene name)|psi-mi:Sdhb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_075863.2|ensembl:ENSMUSG00000009863(gene)|ensembl:ENSMUST00000010007(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0045273"(respiratory chain complex II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|mint:Q9CQA3|reactome:R-MMU-71403	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:867rMxM9LEdIwyu93mUmDNc1S0o10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:O35643	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-348937|uniprotkb:Q3TXG4|uniprotkb:Q922E2|ensembl:ENSMUSP00000009234	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ap1b1_mouse(display_long)|uniprotkb:Ap1b1(gene name)|psi-mi:Ap1b1(display_short)|uniprotkb:Adtb1(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_031480.2|ensembl:ENSMUSG00000009090(gene)|ensembl:ENSMUST00000009234(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048268"(clathrin coat assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:zTEB4qq5OQCyxOOnVs9OeWAQBqA10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9JJI8	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-4286104|ensembl:ENSMUSP00000080741|ensembl:ENSMUSP00000102209|ensembl:ENSMUSP00000102211|ensembl:ENSMUSP00000102213	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rl38_mouse(display_long)|uniprotkb:Rpl38(gene name)|psi-mi:Rpl38(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001041522.1|refseq:NP_001041523.1|refseq:NP_075861.1|refseq:XP_006534072.1|go:"GO:0033291"(eukaryotic 80S initiation complex)|go:"GO:0034463"(90S preribosome assembly)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0048318"(axial mesoderm development)|interpro:IPR002675(Ribosomal protein L38e)|interpro:IPR038464|mint:Q9JJI8|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0022626"(cytosolic ribosome)|refseq:XP_017170209.1|ensembl:ENSMUSG00000057322(gene)|ensembl:ENSMUST00000077915(transcript)|ensembl:ENSMUST00000082092(transcript)|ensembl:ENSMUST00000106599(transcript)|ensembl:ENSMUST00000106602(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022618"(ribonucleoprotein complex assembly)|go:"GO:0022625"(cytosolic large ribosomal subunit)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:rs3Syk5fg3yYGcZm6oXRx/ORc2Q10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q6PIE5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:B2RXT3	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564766|ensembl:ENSMUSP00000154185	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:b2rxt3_mouse(display_long)|uniprotkb:Ogdhl(gene name)|psi-mi:Ogdhl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001074599.1|refseq:XP_006519014.1|ensembl:ENSMUSG00000021913(gene)|ensembl:ENSMUST00000228529(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:LqIbHDr2Fb7M3okuFySeq9hQSDk10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9CRB9	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-299847|ensembl:ENSMUSP00000070149	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:mic19_mouse(display_long)|uniprotkb:Chchd3(gene name)|psi-mi:Chchd3(display_short)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:Mic19(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000053768(gene)|ensembl:ENSMUST00000066379(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0019902"(phosphatase binding)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|mint:Q9CRB9|refseq:NP_079612.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:rxWY2UHnmX3tUiI8/TrJxthCxc010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q3TB96	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564754	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:q3tb96_mouse(display_long)|uniprotkb:Dctn1(gene name)|psi-mi:Dctn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	interpro:IPR036859|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|go:"GO:0005938"(cell cortex)|go:"GO:0030286"(dynein complex)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:W8yy2oLAjYxUGqH8mcl8niuK5iI10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8CIB5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-5545618|uniprotkb:Q8C542|uniprotkb:Q8K035|ensembl:ENSMUSP00000044554	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ferm2_mouse(display_long)|uniprotkb:Fermt2(gene name)|psi-mi:Fermt2(display_short)|uniprotkb:Plekhc1(gene name synonym)|uniprotkb:Kindlin-2(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_666166.2|ensembl:ENSMUSG00000037712(gene)|ensembl:ENSMUST00000045905(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0072657"(protein localization to membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1902462"(positive regulation of mesenchymal stem cell proliferation)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR037837|interpro:IPR037843|interpro:IPR040790|mint:Q8CIB5|rcsb pdb:5XPY|rcsb pdb:5XPZ|rcsb pdb:5XQ0|rcsb pdb:5XQ1|reactome:R-MMU-446353|reactome:R-MMU-9013149|reactome:R-MMU-9013423|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031674"(I band)|go:"GO:0033622"(integrin activation)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035505"(positive regulation of myosin light chain kinase activity)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060173"(limb development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:1WbgMzUL/oPRTZFx+71FShJbDq010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q91YT0	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2934319|ensembl:ENSMUSP00000042967	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:nduv1_mouse(display_long)|uniprotkb:Ndufv1(gene name)|psi-mi:Ndufv1(display_short)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000037916(gene)|ensembl:ENSMUST00000042497(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:Q91YT0|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_598427.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:xYJ5XxA1aRAaXMrlI8U+e9owOPU10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q99LF4	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-6261036|ensembl:ENSMUSP00000001834|uniprotkb:Q3UDW6|uniprotkb:Q3TI25|uniprotkb:Q3TA04	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rtcb_mouse(display_long)|uniprotkb:Rtcb(gene name)|psi-mi:Rtcb(display_short)|uniprotkb:D10Wsu52e(gene name synonym)|uniprotkb:Focal adhesion-associated protein(gene name synonym)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000001783(gene)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q99LF4|ensembl:ENSMUST00000001834(transcript)|refseq:NP_663397.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:ISQNiLQA7DCcgBkTueMDhUHrkFQ10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9D0K2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-645913|uniprotkb:Q9CV92|uniprotkb:Q3TIW6|ensembl:ENSMUSP00000106318	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:scot1_mouse(display_long)|uniprotkb:"Somatic-type succinyl-CoA:3-oxoacid CoA-transferase"(gene name synonym)|uniprotkb:Oxct1(gene name)|psi-mi:Oxct1(display_short)|uniprotkb:Oxct(gene name synonym)|uniprotkb:Scot(gene name synonym)|uniprotkb:3-oxoacid CoA-transferase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_077150.1|interpro:IPR004163(Coenzyme A transferase binding site)|interpro:IPR004164(Coenzyme A transferase active site)|interpro:IPR004165(Coenzyme A transferase)|interpro:IPR012791(3-oxoacid CoA-transferase, subunit B)|interpro:IPR012792(3-oxoacid CoA-transferase, subunit A)|interpro:IPR014388(3-oxoacid CoA-transferase)|interpro:IPR037171|mint:Q9D0K2|reactome:R-MMU-77108|ensembl:ENSMUST00000110690(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008260"(3-oxoacid CoA-transferase activity)|go:"GO:0008410"(CoA-transferase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0014823"(response to activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042182"(ketone catabolic process)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046950"(cellular ketone body metabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|ensembl:ENSMUSG00000022186(gene)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:KSJpQdbufFtI07fqqPLQdJrkT2I10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q01768	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-642573|ensembl:ENSMUSP00000021217|ensembl:ENSMUSP00000103476	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ndkb_mouse(display_long)|uniprotkb:nm23-M2(gene name synonym)|uniprotkb:P18(gene name synonym)|uniprotkb:Nme2(gene name)|psi-mi:Nme2(display_short)|uniprotkb:Histidine protein kinase NDKB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001070997.1|refseq:NP_032731.1|ensembl:ENSMUSG00000020857(gene)|ensembl:ENSMUST00000021217(transcript)|ensembl:ENSMUST00000072566(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1901363"(heterocyclic compound binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:Q01768|reactome:R-MMU-499943|reactome:R-MMU-6798695	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:AJ1Depmyy9zwTEUOZMRO7TKPd1k10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8CI94	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-773709|uniprotkb:Q8K283|ensembl:ENSMUSP00000035743	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:pygb_mouse(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_722476.1|ensembl:ENSMUSG00000033059(gene)|ensembl:ENSMUST00000045441(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q8CI94|reactome:R-MMU-6798695	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:sX820CE/XNwY/LEnJx/j4IF44Lk10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P09405	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-641864|uniprotkb:Q548M9|uniprotkb:Q61991|uniprotkb:Q8BQD8|uniprotkb:Q99K50|ensembl:ENSMUSP00000027438	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:nucl_mouse(display_long)|uniprotkb:Protein C23(gene name synonym)|uniprotkb:Ncl(gene name)|psi-mi:Ncl(display_short)|uniprotkb:Nuc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_035010.3|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042134"(rRNA primary transcript binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990631"(ErbB-4 class receptor binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000232"(regulation of rRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P09405|reactome:R-MMU-6791226|go:"GO:0005634"(nucleus)|ensembl:ENSMUSG00000026234(gene)|ensembl:ENSMUST00000027438(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001650"(fibrillar center)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:NkPifysnX6CafgtN+Ko/p4aBqGE10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q99LC3	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-772722|uniprotkb:Q3UKK0|uniprotkb:Q8BL57|uniprotkb:Q9CW21|ensembl:ENSMUSP00000027478	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:nduaa_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Complex I-42kD(gene name synonym)|uniprotkb:Ndufa10(gene name)|psi-mi:Ndufa10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_077159.1|ensembl:ENSMUSG00000026260(gene)|ensembl:ENSMUST00000027478(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|mint:Q99LC3|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:PnMgq3QghxkpZvkzvgjuJUqkIqY10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8BGH2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2934811|ensembl:ENSMUSP00000023071|uniprotkb:Q3TIL3|uniprotkb:Q3TTG7|uniprotkb:Q3TWD3	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:sam50_mouse(display_long)|uniprotkb:Samm50(gene name)|psi-mi:Samm50(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000022437(gene)|ensembl:ENSMUST00000023071(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0042407"(cristae formation)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|mint:Q8BGH2|reactome:R-MMU-9013404|refseq:NP_848729.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:OWxecVBGU7/ayT7jqSrqeKmr5fw10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P20152	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid://GDvGAXOR4hUXNtVpnZefex5v410090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8C2Q3	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-5692318|uniprotkb:Q3TJB6|uniprotkb:Q91Z21|uniprotkb:Q9DBI6|ensembl:ENSMUSP00000006625	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rbm14_mouse(display_long)|uniprotkb:Rbm14(gene name)|psi-mi:Rbm14(display_short)|uniprotkb:RNA-binding motif protein 14(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_063922.2|dip:DIP-58946N|ensembl:ENSMUSG00000006456(gene)|ensembl:ENSMUST00000006625(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0098534"(centriole assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034506|interpro:IPR034507|interpro:IPR035979|mint:Q8C2Q3|reactome:R-MMU-8941326	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:0jBdPL/CBCwYLIf2A76qx0yJ9RY10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:O08709	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:B7ZCI2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564738|ensembl:ENSMUSP00000117805	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:b7zci2_mouse(display_long)|uniprotkb:Nebl(gene name)|psi-mi:Nebl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000053702(gene)|ensembl:ENSMUST00000124270(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030018"(Z disc)|go:"GO:0031005"(filamin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0071691"(cardiac muscle thin filament assembly)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035631|interpro:IPR036028	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:+fiQSUMncpvsYK0M9GVSnPbO1nU10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8BFR5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-299611|ensembl:ENSMUSP00000095656|uniprotkb:Q497E7|uniprotkb:Q6P919	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eftu_mouse(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000073838(gene)|ensembl:ENSMUST00000098048(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:Q8BFR5|go:"GO:0042645"(mitochondrial nucleoid)|refseq:NP_001157185.1|refseq:NP_766333.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:ax4f72KkJMxjxZD3ZClHh/oby3k10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:A2AQ25	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8821027|ensembl:ENSMUSP00000066170|uniprotkb:A2AUE9|uniprotkb:A2AUF0|uniprotkb:A2AUF1|uniprotkb:Q75UV8|uniprotkb:Q75UV9|uniprotkb:Q80VK2|uniprotkb:Q8BHX8|uniprotkb:Q8BHY1|uniprotkb:Q8CHA8|uniprotkb:Q8R0K6	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:skt_mouse(display_long)|uniprotkb:Skt(gene name)|psi-mi:Skt(display_short)|uniprotkb:Etl4(gene name synonym)|uniprotkb:Kiaa1217(gene name synonym)|uniprotkb:Enhancer trap locus 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	interpro:IPR022782|interpro:IPR026725|mint:A2AQ25|ensembl:ENSMUSG00000036617(gene)|ensembl:ENSMUST00000066509(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0048706"(embryonic skeletal system development)|refseq:NP_001074475.1|refseq:NP_001171101.2|refseq:NP_084171.2|refseq:NP_835160.2|refseq:XP_006497478.1|refseq:XP_006497487.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:WI45C2F/GFoa1PhVnBHPtxCj5mM10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P62855	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-6260985|ensembl:ENSMUSP00000026420|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:P02383	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rs26_mouse(display_long)|uniprotkb:Rps26(gene name)|psi-mi:Rps26(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000025362(gene)|ensembl:ENSMUST00000026420(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|mint:P62855|refseq:NP_038793.2	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9D6R2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-299873|ensembl:ENSMUSP00000127526|uniprotkb:Q3UAM8|uniprotkb:Q8C8A1|uniprotkb:Q9D1L1	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:idh3a_mouse(display_long)|uniprotkb:Idh3a(gene name)|psi-mi:Idh3a(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000032279(gene)|ensembl:ENSMUST00000167866(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q9D6R2|reactome:R-MMU-71403|refseq:NP_083849.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:JkEkbIT34WQdoOiBYA9kAao2lC010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8K1M6	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2365792|uniprotkb:Q8BNQ5|uniprotkb:Q8BQ64|uniprotkb:Q8CGD0|uniprotkb:Q8K1A1	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:dnm1l_mouse(display_long)|uniprotkb:Dnm1l(gene name)|psi-mi:Dnm1l(display_short)|uniprotkb:Drp1(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001021118.1|refseq:XP_006522694.1|refseq:NP_001263269.1|refseq:NP_001263270.1|refseq:NP_690029.2|dip:DIP-54818N|mint:Q8K1M6|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|reactome:R-MMU-75153|go:"GO:0005903"(brush border)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:5yGX3+QNfz3+dKRHA2ffkIVq3yU10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P60335	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-309059|ensembl:ENSMUSP00000054863	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:pcbp1_mouse(display_long)|uniprotkb:Pcbp1(gene name)|psi-mi:Pcbp1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_035995.1|ensembl:ENSMUSG00000051695(gene)|ensembl:ENSMUST00000053015(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008494"(translation activator activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P60335|reactome:R-MMU-72163|reactome:R-MMU-72203	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:x72fawo4plQ+ipfqIoREIDHc2bA10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8CGY6	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564709|uniprotkb:Q5XG72|uniprotkb:Q8BHC5|uniprotkb:Q8BWK3|ensembl:ENSMUSP00000103795|ensembl:ENSMUSP00000129405	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:un45b_mouse(display_long)|uniprotkb:Unc45b(gene name)|psi-mi:Unc45b(display_short)|uniprotkb:Cmya4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_848795.3|ensembl:ENSMUSG00000018845(gene)|ensembl:ENSMUST00000108160(transcript)|ensembl:ENSMUST00000164945(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0030154"(cell differentiation)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019734|interpro:IPR024660	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:Xetcx0PhEqUjY8JYtoKmEouOCJk10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P40142	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-494230|uniprotkb:Q3U7Y1|uniprotkb:Q3UK62|uniprotkb:Q545A1|uniprotkb:Q9ESA0|ensembl:ENSMUSP00000022529	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:tkt_mouse(display_long)|uniprotkb:P68(gene name synonym)|uniprotkb:Tkt(gene name)|psi-mi:Tkt(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_033414.1|ensembl:ENSMUSG00000021957(gene)|ensembl:ENSMUST00000022529(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004802"(transketolase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0016604"(nuclear body)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|mint:P40142|reactome:R-MMU-163754|reactome:R-MMU-71336	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:h2YT3KKVrgDmPcSbJmtevBv1CAI10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q61768	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-776129|uniprotkb:Q5BL10|uniprotkb:O08711|uniprotkb:Q61580|ensembl:ENSMUSP00000025083	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:kinh_mouse(display_long)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Khcs(gene name synonym)|uniprotkb:Kns1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_032474.2|dip:DIP-32053N|ensembl:ENSMUSG00000006740(gene)|ensembl:ENSMUST00000025083(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q61768|rcsb pdb:6IGN|rcsb pdb:6IGV|reactome:R-MMU-2132295|reactome:R-MMU-5625970|reactome:R-MMU-6811434|reactome:R-MMU-983189	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:11aePhwWZOqqAabjyanVgdHQQso10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P19096	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-773277|uniprotkb:Q6PB72|uniprotkb:Q8C4Z0|uniprotkb:Q9EQR0|uniprotkb:B1ATU8|ensembl:ENSMUSP00000052872	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:fas_mouse(display_long)|uniprotkb:Fasn(gene name)|psi-mi:Fasn(display_short)|uniprotkb:Type I Fatty Acid Synthase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_032014.3|ensembl:ENSMUSG00000025153(gene)|ensembl:ENSMUST00000055655(transcript)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0004312"(fatty acid synthase activity)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0009888"(tissue development)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P19096|rcsb pdb:5MY0|rcsb pdb:5MY2|rcsb pdb:6ROP|reactome:R-MMU-163765|reactome:R-MMU-199220|reactome:R-MMU-75105	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:k+MkpzkPX8N0Diy3ovhliRvu73M10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q3U5I2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564695	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:q3u5i2_mouse(display_long)|uniprotkb:Ptbp1(gene name)|psi-mi:Ptbp1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	interpro:IPR021790|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034798|interpro:IPR035000|interpro:IPR035001|interpro:IPR035979|interpro:IPR000504(RNA recognition motif, RNP-1)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:hOvTJzR8bSCyX22LYtYXP3ckx4A10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q3U6P5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-6876909	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:q3u6p5_mouse(display_long)|uniprotkb:Hnrnpc(gene name)|psi-mi:Hnrnpc(display_short)|uniprotkb:Hnrpc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:0003723"(RNA binding)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:hRyOOySi9XS/ImNLcBIyBioJHjc10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9QXX4	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-775952|uniprotkb:Q9CZF6|uniprotkb:Q9DCF5|ensembl:ENSMUSP00000015256|ensembl:ENSMUSP00000139571	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:cmc2_mouse(display_long)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)|uniprotkb:Slc25a13(gene name)|psi-mi:Slc25a13(display_short)|uniprotkb:Aralar2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001171043.1|refseq:NP_056644.1|ensembl:ENSMUSG00000015112(gene)|ensembl:ENSMUST00000015256(transcript)|ensembl:ENSMUST00000188414(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9QXX4|reactome:R-MMU-70263|reactome:R-MMU-8963693	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:c7qSgch4lV/J3PGriiqzNknznm010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:O08638	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-400926|uniprotkb:O08639|uniprotkb:Q62462|uniprotkb:Q64195	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:myh11_mouse(display_long)|uniprotkb:Myh11(gene name)|psi-mi:Myh11(display_short)|uniprotkb:Myosin heavy chain 11(gene name synonym)|uniprotkb:Myosin heavy chain, smooth muscle isoform(gene name synonym)|uniprotkb:SMMHC(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	interpro:IPR002928(Myosin tail)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|go:"GO:0001725"(stress fiber)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005903"(brush border)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032982"(myosin filament)|go:"GO:0042470"(melanosome)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0055013"(cardiac muscle cell development)|reactome:R-MMU-445355|reactome:R-MMU-5627123|interpro:IPR036961|mint:O08638|interpro:IPR008989(Myosin S1 fragment, N-terminal)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:EdcqmWrGhLwLHapCFYE4pwsHmtg10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P47963	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-445016|uniprotkb:Q9CRZ9|uniprotkb:Q9DCH1|ensembl:ENSMUSP00000000756	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rl13_mouse(display_long)|uniprotkb:A52(gene name synonym)|uniprotkb:Rpl13(gene name)|psi-mi:Rpl13(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_058018.2|ensembl:ENSMUSG00000000740(gene)|ensembl:ENSMUST00000000756(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0060348"(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P47963|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0022626"(cytosolic ribosome)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:s4+tKYYhhfFHM5TZCNIgbE2hQds10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q6PHZ2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2308458|uniprotkb:Q3UF87|uniprotkb:Q3UQH9|uniprotkb:Q5DTK4|uniprotkb:Q8CAC5|uniprotkb:Q9CZE2|ensembl:ENSMUSP00000143504	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:kcc2d_mouse(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001020609.1|refseq:NP_076302.1|refseq:NP_001020610.1|refseq:NP_001280592.1|refseq:NP_001280593.1|dip:DIP-47638N|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000199300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q6PHZ2|rcsb pdb:6BAB|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P62204	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-397460|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q3TEH7|uniprotkb:Q3THK5|uniprotkb:Q3U6Z5|uniprotkb:Q3U7C7|uniprotkb:Q498A3|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q8BNC9|uniprotkb:Q91VQ9|uniprotkb:Q9D6G4|dip:DIP-31550N|uniprotkb:P0DP26|uniprotkb:P0DP28	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:calm_mouse(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:Cam(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	rcsb pdb:3WFN|rcsb pdb:4HEX|go:"GO:0005509"(calcium ion binding)|go:"GO:0000922"(spindle pole)|refseq:NP_031615.1|refseq:NP_031616.1|refseq:NP_033920.1|rcsb pdb:2IX7|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:2DFS|refseq:NP_001300863.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0043388"(positive regulation of DNA binding)|reactome:R-MMU-2672351|reactome:R-MMU-418359|reactome:R-MMU-425561|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0005829"(cytosol)|reactome:R-MMU-8876725|rcsb pdb:4E50|rcsb pdb:4E53|go:"GO:0061024"(membrane organization)|rcsb pdb:4ZLK|reactome:R-MMU-1445148|reactome:R-MMU-5576892|ensembl:ENSMUST00000019514|ensembl:ENSMUST00000040440|ensembl:ENSMUST00000110082|reactome:R-MMU-111932|reactome:R-MMU-111933|reactome:R-MMU-111957|reactome:R-MMU-114608|reactome:R-MMU-1474151|reactome:R-MMU-1855204|reactome:R-MMU-203615|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-442717|reactome:R-MMU-442729|reactome:R-MMU-442745|reactome:R-MMU-442982|reactome:R-MMU-445355|reactome:R-MMU-451308|reactome:R-MMU-5607763|reactome:R-MMU-5626467|reactome:R-MMU-5218920|reactome:R-MMU-5627123|reactome:R-MMU-5673001|reactome:R-MMU-70221|ensembl:ENSMUSG00000001175|ensembl:ENSMUSG00000019370|ensembl:ENSMUSG00000036438|ensembl:ENSMUSP00000019514|ensembl:ENSMUSP00000048857|ensembl:ENSMUSP00000105709|reactome:R-MMU-2514859|reactome:R-MMU-163615|go:"GO:0034704"(calcium channel complex)|go:"GO:0005813"(centrosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030426"(growth cone)|go:"GO:0005634"(nucleus)|go:"GO:0030017"(sarcomere)|go:"GO:0005876"(spindle microtubule)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0002027"(regulation of heart rate)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|go:"GO:0021762"(substantia nigra development)|rcsb pdb:1UP5|go:"GO:1902494"(catalytic complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0043209"(myelin sheath)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031432"(titin binding)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|reactome:R-MMU-2025928|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0051300"(spindle pole body organization)|interpro:IPR039030	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:tTYcOd9bOh211njZVz7cYVybAMQ10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9Z2I8	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2107688|uniprotkb:Q3T9B8|uniprotkb:Q3TJQ5|uniprotkb:Q3TK63|uniprotkb:Q66JT3|uniprotkb:Q7TMY3|uniprotkb:Q80VV1|uniprotkb:Q8K2K9|ensembl:ENSMUSP00000144827	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:sucb2_mouse(display_long)|uniprotkb:Suclg2(gene name)|psi-mi:Suclg2(display_short)|uniprotkb:GTP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-G chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001313487.1|refseq:NP_035637.2|ensembl:ENSMUSG00000061838(gene)|ensembl:ENSMUST00000204224(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034722|mint:Q9Z2I8|reactome:R-MMU-71403	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:V1vkzx6MwooUIe9d/A66CRAoygA10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q05504	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564682	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:q05504_mouse(display_long)|uniprotkb:Col6a3(gene name)|psi-mi:Col6a3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042383"(sarcolemma)|go:"GO:0062023"(collagen-containing extracellular matrix)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:bGfhWrmwdQEoDqhkRyYkMvL0Q9810090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9CR68	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-1219616|uniprotkb:Q5SVV1|ensembl:ENSMUSP00000045284	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ucri_mouse(display_long)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:Uqcrfs1(gene name)|psi-mi:Uqcrfs1(display_short)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_079986.1|mint:Q9CR68|reactome:R-MMU-611105|ensembl:ENSMUSG00000038462(gene)|ensembl:ENSMUST00000042834(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:nlXLFf9AMJ4fhZUsdE8cVraBuW410090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q3TIY5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564649	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:q3tiy5_mouse(display_long)|uniprotkb:Pkp2(gene name)|psi-mi:Pkp2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR000225(Armadillo)|interpro:IPR028435|go:"GO:0002159"(desmosome assembly)|go:"GO:0002934"(desmosome organization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014704"(intercalated disc)|go:"GO:0016264"(gap junction assembly)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:2000810"(regulation of bicellular tight junction assembly)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:eDOOnl66XwsyJsdjGjKBMguMBMA10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:O08749	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-773199|uniprotkb:Q3TG55|uniprotkb:Q3U5W5|uniprotkb:Q3UWP7|uniprotkb:Q99LD3|ensembl:ENSMUSP00000106481	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:dldh_mouse(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Dld(gene name)|psi-mi:Dld(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_031887.2|ensembl:ENSMUSG00000020664(gene)|ensembl:ENSMUST00000110857(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043209"(myelin sheath)|go:"GO:0043544"(lipoamide binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:O08749|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-6783984|reactome:R-MMU-70268|reactome:R-MMU-70895|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:6j/8rw4lkNMW4Lo5sGoRdDJBk2w10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8C8R3	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-774322|intact:EBI-2133064|uniprotkb:Q6PCN2|uniprotkb:Q3TM62|uniprotkb:Q3V2X0|uniprotkb:Q80ZZ7|uniprotkb:Q8BNC1|uniprotkb:Q8C445|uniprotkb:Q8CCV0|intact:EBI-2255612|intact:EBI-8314005|intact:MINT-4115219	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ank2_mouse(display_long)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:AnkB(gene name synonym)|uniprotkb:Ank2(gene name)|psi-mi:Ank2(display_short)|uniprotkb:Ankyrin-B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001029340.1|refseq:NP_848770.2|dip:DIP-58645N|mint:Q8C8R3|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001257"(regulation of cation channel activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:SkB13oxZVcKuMnI8r5ItFIq2pXQ10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8CC88	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-12602574|ensembl:ENSMUSP00000048925|uniprotkb:Q3U4P9|uniprotkb:Q6ZQ94|uniprotkb:Q8CDH8|uniprotkb:Q8VCU3	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:vwa8_mouse(display_long)|uniprotkb:Vwa8(gene name)|psi-mi:Vwa8(display_short)|uniprotkb:Kiaa0564(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000058997(gene)|ensembl:ENSMUST00000040990(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|mint:Q8CC88|refseq:NP_082182.1|refseq:NP_776119.2	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:JRlZvEqyEowI+W/4vQZy0mZEQk810090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P63242	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2255623|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q5NCX0|uniprotkb:Q78NR3|uniprotkb:Q9D0G2|ensembl:ENSMUSP00000047008|ensembl:ENSMUSP00000067077|ensembl:ENSMUSP00000068651|ensembl:ENSMUSP00000104247|ensembl:ENSMUSP00000104248|ensembl:ENSMUSP00000104249|ensembl:ENSMUSP00000104250|ensembl:ENSMUSP00000104251|ensembl:ENSMUSP00000104252|ensembl:ENSMUSP00000104253|ensembl:ENSMUSP00000132717	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:if5a1_mouse(display_long)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Eif5a(gene name)|psi-mi:Eif5a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:XP_011247360.1|refseq:NP_001160064.1|refseq:NP_001160065.1|refseq:NP_001160066.1|refseq:NP_001160061.1|refseq:NP_001160062.1|refseq:NP_001160063.1|refseq:NP_001160067.1|refseq:NP_001160068.1|refseq:NP_853613.1|ensembl:ENSMUSG00000078812(gene)|ensembl:ENSMUST00000043419(transcript)|ensembl:ENSMUST00000070996(transcript)|ensembl:ENSMUST00000071026(transcript)|ensembl:ENSMUST00000108607(transcript)|ensembl:ENSMUST00000108608(transcript)|ensembl:ENSMUST00000108609(transcript)|ensembl:ENSMUST00000108610(transcript)|ensembl:ENSMUST00000108611(transcript)|ensembl:ENSMUST00000108612(transcript)|ensembl:ENSMUST00000108613(transcript)|ensembl:ENSMUST00000164359(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007568"(aging)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0015031"(protein transport)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030425"(dendrite)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63242|reactome:R-MMU-204626	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:/smk81DLs+XvrqXmIZpfvdHHauk10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P05202	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-444923|uniprotkb:Q3TIP6|uniprotkb:Q3UD91|uniprotkb:Q5HZH5|uniprotkb:O09188|ensembl:ENSMUSP00000034097	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:aatm_mouse(display_long)|uniprotkb:Transaminase A(gene name synonym)|uniprotkb:Glutamate oxaloacetate transaminase 2(gene name synonym)|uniprotkb:Fatty acid-binding protein(gene name synonym)|uniprotkb:Plasma membrane-associated fatty acid-binding protein(gene name synonym)|uniprotkb:Kynurenine aminotransferase 4(gene name synonym)|uniprotkb:Kynurenine aminotransferase IV(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase 4(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase IV(gene name synonym)|uniprotkb:Got2(gene name)|psi-mi:Got2(display_short)|uniprotkb:Got-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_034455.1|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0045471"(response to ethanol)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P05202|rcsb pdb:3HLM|rcsb pdb:3PD6|rcsb pdb:3PDB|reactome:R-MMU-389661|reactome:R-MMU-8963693|reactome:R-MMU-8964539|reactome:R-MMU-70263|ensembl:ENSMUST00000034097(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0009986"(cell surface)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0016597"(amino acid binding)|go:"GO:0019550"(glutamate catabolic process to aspartate)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030315"(T-tubule)|ensembl:ENSMUSG00000031672(gene)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:derWMXIiDl1XkaQdJ48VFA7HMzM10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q91VR2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-444750|ensembl:ENSMUSP00000110547	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:atpg_mouse(display_long)|uniprotkb:Atp5f1c(gene name)|psi-mi:Atp5f1c(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:Atp5c1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_065640.2|ensembl:ENSMUSG00000025781(gene)|ensembl:ENSMUST00000114897(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|reactome:R-MMU-163210|reactome:R-MMU-8949613	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:HXjj4Rj2J2QsW3UFM47mHOYS2VI10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P62918	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-6910319|ensembl:ENSMUSP00000004072|ensembl:ENSMUSP00000155657|uniprotkb:P25120|uniprotkb:Q3V288	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rl8_mouse(display_long)|uniprotkb:Rpl8(gene name)|psi-mi:Rpl8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62918|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000003970(gene)|ensembl:ENSMUST00000004072(transcript)|ensembl:ENSMUST00000229183(transcript)|go:"GO:0002181"(cytoplasmic translation)|refseq:NP_036183.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9ERS2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2934630|ensembl:ENSMUSP00000105796|uniprotkb:Q9DC98|uniprotkb:Q9DCA1	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:nduad_mouse(display_long)|uniprotkb:Ndufa13(gene name)|psi-mi:Ndufa13(display_short)|uniprotkb:Grim19(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000036199(gene)|ensembl:ENSMUST00000110167(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9ERS2|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_075801.1|refseq:XP_017168432.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:wgq95IYdQM3hRpOywBXA0Axqil010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P62900	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2527089|uniprotkb:P12947|ensembl:ENSMUSP00000083722|ensembl:ENSMUSP00000136354|ensembl:ENSMUSP00000137631	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rl31_mouse(display_long)|uniprotkb:Rpl31(gene name)|psi-mi:Rpl31(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000073702(gene)|ensembl:ENSMUST00000086535(transcript)|ensembl:ENSMUST00000178079(transcript)|ensembl:ENSMUST00000179954(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62900|rcsb pdb:6SWA|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-156827|refseq:NP_444487.1|refseq:NP_001239147.1|refseq:NP_001239148.1	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:77LFR7/2somk6blVogZf1XFdJLk10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P29341	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-773902|uniprotkb:Q99L36|ensembl:ENSMUSP00000001809	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:pabp1_mouse(display_long)|uniprotkb:Pabpc1(gene name)|psi-mi:Pabpc1(display_short)|uniprotkb:Pabp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	dip:DIP-32127N|refseq:NP_032800.2|refseq:XP_011243641.1|ensembl:ENSMUSG00000022283(gene)|ensembl:ENSMUST00000001809(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045202"(synapse)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P29341|reactome:R-MMU-156827|reactome:R-MMU-429947|reactome:R-MMU-450408|reactome:R-MMU-72649|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:jvlQW6kphF2tkZwK72DtAXDPHvs10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P58281	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-776163|uniprotkb:Q3ULA5|uniprotkb:Q8BKU7|uniprotkb:Q8BLL3|uniprotkb:Q8BM08|uniprotkb:Q8R3J7|uniprotkb:A6H6Q3|ensembl:ENSMUSP00000124223	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:opa1_mouse(display_long)|uniprotkb:Optic atrophy protein 1 homolog(gene name synonym)|uniprotkb:Large GTP-binding protein(gene name synonym)|uniprotkb:Opa1(gene name)|psi-mi:Opa1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_598513.1|refseq:XP_006522720.1|ensembl:ENSMUSG00000038084(gene)|ensembl:ENSMUST00000160597(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001843"(neural tube closure)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007601"(visual perception)|go:"GO:0008017"(microtubule binding)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030425"(dendrite)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090102"(cochlea development)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090398"(cellular senescence)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904643"(response to curcumin)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR033047|mint:P58281|reactome:R-MMU-169911	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:cj1HZs8CYUuCBy4KhYmtO/lvmUk10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9CQC7	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2255646|ensembl:ENSMUSP00000023514	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:ndub4_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym)|uniprotkb:Ndufb4(gene name)|psi-mi:Ndufb4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_080886.1|refseq:XP_001476621.1|refseq:XP_001478493.1|ensembl:ENSMUSG00000022820(gene)|ensembl:ENSMUST00000023514(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|mint:Q9CQC7|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:bOgcV3wmpY11CMgEaMUGzcugRiM10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q01853	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-80597|ensembl:ENSMUSP00000030164|uniprotkb:Q3TFH9|uniprotkb:Q3TIM2|uniprotkb:Q3TXN9|uniprotkb:Q6PI18|uniprotkb:Q8BSR6|uniprotkb:Q8CEG4	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:tera_mouse(display_long)|uniprotkb:Vcp(gene name)|psi-mi:Vcp(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:Q01853|rcsb pdb:1E32|rcsb pdb:1R7R|rcsb pdb:1S3S|rcsb pdb:2PJH|rcsb pdb:3CF0|rcsb pdb:3CF1|rcsb pdb:3CF2|rcsb pdb:3CF3|reactome:R-MMU-110320|reactome:R-MMU-3371511|reactome:R-MMU-382556|reactome:R-MMU-532668|reactome:R-MMU-5358346|reactome:R-MMU-5689877|reactome:R-MMU-5689896|reactome:R-MMU-6798695|reactome:R-MMU-8876725|reactome:R-MMU-9013407|ensembl:ENSMUSG00000028452(gene)|ensembl:ENSMUST00000030164(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0019904"(protein domain specific binding)|refseq:NP_033529.3|dip:DIP-29796N	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q08284	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564643	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:q08284_mouse(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	interpro:IPR021996|go:"GO:0007596"(blood coagulation)|interpro:IPR037579	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:kU9SIvw8LtejHyKpN2cXStuUFXU10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q7TMF3	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2934615|ensembl:ENSMUSP00000020209|uniprotkb:Q3TIA0	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:nduac_mouse(display_long)|uniprotkb:Ndufa12(gene name)|psi-mi:Ndufa12(display_short)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUST00000020209(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|ensembl:ENSMUSG00000020022(gene)|refseq:NP_079827.2	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:ABTsOaXBN3GSTwTETzzEvOfVMiQ10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:A6H663	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-9987195	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:a6h663_mouse(display_long)|uniprotkb:Bag3(gene name)|psi-mi:Bag3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:0051087"(chaperone binding)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:xdE25m8ClXN+W57r6hTmYtW7JEs10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9D0E1	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-773789|uniprotkb:Q6P1B2|uniprotkb:Q99JQ0|ensembl:ENSMUSP00000120115	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:hnrpm_mouse(display_long)|uniprotkb:Hnrpm(gene name synonym)|uniprotkb:Hnrnpm(gene name)|psi-mi:Hnrnpm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001103383.1|refseq:NP_084080.1|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904591"(positive regulation of protein import)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024666|interpro:IPR024667|interpro:IPR034990|interpro:IPR035979|mint:Q9D0E1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|ensembl:ENSMUSG00000059208(gene)|ensembl:ENSMUST00000148178(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0048306"(calcium-dependent protein binding)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:VpoWJwPx1uDzAsBxM3/TfiCMGok10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9D828	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-308969	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:q9d828_mouse(display_long)|uniprotkb:Tfg(gene name)|psi-mi:Tfg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|interpro:IPR034857|interpro:IPR033512	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:ROdjt7CfqfZJ3ELcZihI3jIUG5A10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8R1M2	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564609|ensembl:ENSMUSP00000074142	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:h2aj_mouse(display_long)|uniprotkb:H2aj(gene name)|psi-mi:H2aj(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_808356.1|ensembl:ENSMUSG00000060032(gene)|ensembl:ENSMUST00000074556(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-5689901|reactome:R-MMU-606279|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:lI0jGp2Briu5wEo5TJrE+FPOocI10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q3TSA5	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564594	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:q3tsa5_mouse(display_long)|uniprotkb:Pabpc4(gene name)|psi-mi:Pabpc4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR036053|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:WFmYVUqfxdBLyC5d6vIUVI4vjbg10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P70404	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-773416|ensembl:ENSMUSP00000056502	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:idhg1_mouse(display_long)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)|uniprotkb:Idh3g(gene name)|psi-mi:Idh3g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_032349.1|ensembl:ENSMUSG00000002010(gene)|ensembl:ENSMUST00000052761(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P70404|reactome:R-MMU-71403	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:0wCp92dH0hTrNyYmucC9Ob73aBU10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P11152	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-8801123|ensembl:ENSMUSP00000015712|ensembl:ENSMUSP00000132259|uniprotkb:Q05956|uniprotkb:Q542L4|uniprotkb:Q9D3M9|uniprotkb:Q9DCM8	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:lipl_mouse(display_long)|uniprotkb:Lpl(gene name)|psi-mi:Lpl(display_short)|uniprotkb:Phospholipase A1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016298"(lipase activity)|go:"GO:0017129"(triglyceride binding)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000734(Lipase)|interpro:IPR001024(Lipoxygenase, LH2)|go:"GO:0042627"(chylomicron)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|mint:P11152|reactome:R-MMU-8963889|reactome:R-MMU-8963901|reactome:R-MMU-975634|interpro:IPR002330(Lipoprotein lipase)|ensembl:ENSMUSG00000015568(gene)|ensembl:ENSMUST00000015712(transcript)|ensembl:ENSMUST00000168401(transcript)|go:"GO:0004465"(lipoprotein lipase activity)|go:"GO:0004620"(phospholipase activity)|refseq:NP_032535.2	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:/olkwrWXSqe8ZnXKzPwBVm74uc010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P14206	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q5SXR6	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2308526|ensembl:ENSMUSP00000050220	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:q5sxr6_mouse(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000047126(gene)|ensembl:ENSMUST00000060766(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:zQkMlHHZuHQwJ3cU5pWAx/f6guc10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q9Z1D1	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-642408|uniprotkb:Q9R079|ensembl:ENSMUSP00000004206	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3g_mouse(display_long)|uniprotkb:Eif3s4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym)|uniprotkb:Eif3g(gene name)|psi-mi:Eif3g(display_short)|uniprotkb:Eif3p42(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_058572.2|ensembl:ENSMUSG00000070319(gene)|ensembl:ENSMUST00000004206(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:Q9Z1D1|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:Tg6eCPZZkVgKsOicPmasuzr8gYs10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8VHX6	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-400843|uniprotkb:Q6PAI6|uniprotkb:B2RY80|uniprotkb:B9EKT2|uniprotkb:Q9JJ38|ensembl:ENSMUSP00000064163	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:flnc_mouse(display_long)|uniprotkb:Flnc(gene name)|psi-mi:Flnc(display_short)|uniprotkb:Abpl(gene name synonym)|uniprotkb:Fln2(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_001074654.1|refseq:NP_001298003.1|ensembl:ENSMUSG00000068699(gene)|mint:Q8VHX6|ensembl:ENSMUST00000065090(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-MMU-446353	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:xohwAtNkerMr1ZBB5Pi8QLYPo0Y10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8K310	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-1216295|ensembl:ENSMUSP00000125761|ensembl:ENSMUSP00000158074|ensembl:ENSMUSP00000158537	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:matr3_mouse(display_long)|uniprotkb:Matr3(gene name)|psi-mi:Matr3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_034901.2|rcsb pdb:1X4F|rcsb pdb:1X4D|ensembl:ENSMUSG00000037236(gene)|ensembl:ENSMUST00000166793(transcript)|ensembl:ENSMUST00000235199(transcript)|ensembl:ENSMUST00000237744(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034928|interpro:IPR034930|interpro:IPR035979|mint:Q8K310	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:AwtFbI+oRfha+mn/v3yzG6bNXYg10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P60229	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2678912|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|ensembl:ENSMUSP00000022960	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3e_mouse(display_long)|uniprotkb:Eif3e(gene name)|psi-mi:Eif3e(display_short)|uniprotkb:Eif3s6(gene name synonym)|uniprotkb:Int6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Mammary tumor-associated protein INT-6(gene name synonym)|uniprotkb:Viral integration site protein INT-6(gene name synonym)|uniprotkb:MMTV integration site 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_032414.1|ensembl:ENSMUSG00000022336(gene)|ensembl:ENSMUST00000022960(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60229|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|dip:DIP-44570N	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:s09LicCa0mb9WwO7esZvVdvUonY10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:B0LAD0	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-20564586	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:b0lad0_mouse(display_long)|uniprotkb:Eif3f(gene name)|psi-mi:Eif3f(display_short)|uniprotkb:Eif3s5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0031369"(translation initiation factor binding)|interpro:IPR027531	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:Yf6S2BdZvV8Q8+Or2gT0upXdFF010090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:O70194	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-773893|uniprotkb:Q8BLH0|uniprotkb:Q8BWW1|ensembl:ENSMUSP00000098053	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3d_mouse(display_long)|uniprotkb:Eif3s7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym)|uniprotkb:Eif3d(gene name)|psi-mi:Eif3d(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_061219.2|refseq:XP_006521255.1|ensembl:ENSMUSG00000016554(gene)|ensembl:ENSMUST00000100484(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O70194|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:3AScEAsTKzZ+lSa6oU8pPy6UxgM10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:Q8JZQ9	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-4286513|uniprotkb:Q922K2|ensembl:ENSMUSP00000098076	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3b_mouse(display_long)|uniprotkb:Eif3b(gene name)|psi-mi:Eif3b(display_short)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:Eif3s9(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	refseq:NP_598677.1|ensembl:ENSMUSG00000056076(gene)|ensembl:ENSMUST00000100507(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045202"(synapse)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:Q8JZQ9|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:Mi9GReY+V693P20QOUsHizsl5DY10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P97414	uniprotkb:P23116	intact:EBI-9869724|uniprotkb:O88702|uniprotkb:Q3U4H1|uniprotkb:Q7TNZ1|uniprotkb:Q7TPL7|uniprotkb:Q80VR7|ensembl:ENSMUSP00000009689	intact:EBI-2552342|uniprotkb:E9QQ50|ensembl:ENSMUSP00000025955|uniprotkb:Q62162|uniprotkb:Q60697	psi-mi:kcnq1_mouse(display_long)|uniprotkb:Kcnq1(gene name)|psi-mi:Kcnq1(display_short)|uniprotkb:Kcna9(gene name synonym)|uniprotkb:Kvlqt1(gene name synonym)|uniprotkb:IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1(gene name synonym)|uniprotkb:KQT-like 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv7.1(gene name synonym)	psi-mi:eif3a_mouse(display_long)|uniprotkb:Eif3a(gene name)|psi-mi:Eif3a(display_short)|uniprotkb:Csma(gene name synonym)|uniprotkb:Eif3(gene name synonym)|uniprotkb:Eif3s10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)|uniprotkb:p162(gene name synonym)|uniprotkb:Centrosomin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564572|imex:IM-26422-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032460.2|ensembl:ENSMUSG00000009545(gene)|ensembl:ENSMUST00000009689(transcript)|go:"GO:0001696"(gastric acid secretion)|go:"GO:0001698"(gastrin-induced gastric acid secretion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0007507"(heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007622"(rhythmic behavior)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010467"(gene expression)|go:"GO:0015271"(outward rectifier potassium channel activity)|go:"GO:0015705"(iodide transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0030133"(transport vesicle)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0032409"(regulation of transporter activity)|go:"GO:0032868"(response to insulin)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034702"(ion channel complex)|go:"GO:0034705"(potassium channel complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035176"(social behavior)|go:"GO:0035690"|go:"GO:0035934"(corticosterone secretion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0048839"(inner ear development)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060372"(regulation of atrial cardiac muscle cell membrane repolarization)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0060453"(regulation of gastric acid secretion)|go:"GO:0060454"(positive regulation of gastric acid secretion)|go:"GO:0061337"(cardiac conduction)|go:"GO:0062094"(stomach development)|go:"GO:0070293"(renal absorption)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071871"(response to epinephrine)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071875"(adrenergic receptor signaling pathway)|go:"GO:0072347"(response to anesthetic)|go:"GO:0072359"(circulatory system development)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086008"(voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086089"(voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090102"(cochlea development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097546"(ciliary base)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098914"(membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903817"(negative regulation of voltage-gated potassium channel activity)|go:"GO:1905150"(regulation of voltage-gated sodium channel activity)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990794"(basolateral part of cell)|interpro:IPR003937(Potassium channel, voltage dependent, KCNQ)|interpro:IPR005821(Ion transport)|interpro:IPR005827(Potassium channel, voltage dependent, KCNQ1, subgroup 1)|interpro:IPR013821(Potassium channel, voltage dependent, KCNQ, C-terminal)|interpro:IPR027359|interpro:IPR028325|reactome:R-MMU-1296072|reactome:R-MMU-5576890|reactome:R-MMU-5576893	ensembl:ENSMUSG00000024991(gene)|ensembl:ENSMUST00000025955(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:P23116|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|go:"GO:0014069"(postsynaptic density)|refseq:NP_034253.3	-	-	-	figure legend:Table S3, Fig. S1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/25	rogid:bgtBdeI6TKKuHiBwNl/nZ4x0U+s10090	rogid:oL2Xlz5tghN0YkjvCd3nXOj15Hk10090	rigid:zDBvrnMMESD6dmedfm20zLAphgM	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q60936	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-8347051|uniprotkb:Q8K0M1|uniprotkb:Q9D657|uniprotkb:Q9JHR3|uniprotkb:Q9DBR5|intact:MINT-1859515|ensembl:ENSMUSP00000027766|ensembl:ENSMUSP00000128290	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:coq8a_mouse(display_long)|uniprotkb:Coq8a(gene name)|psi-mi:Coq8a(display_short)|uniprotkb:Adck3(gene name synonym)|uniprotkb:Cabc1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_075830.2|refseq:NP_001156762.1|refseq:XP_006497024.1|refseq:XP_006497025.1|ensembl:ENSMUSG00000026489(gene)|ensembl:ENSMUST00000027766(transcript)|ensembl:ENSMUST00000170472(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|mint:Q60936	-	-	function:May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain|comment:mint	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:mBL+f8T49kJm+ryI9VCRcUFyLZM10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P62267	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-8313545|ensembl:ENSMUSP00000054490|uniprotkb:P39028|uniprotkb:Q542K7|intact:MINT-1857177	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:rs23_mouse(display_long)|uniprotkb:Rps23(gene name)|psi-mi:Rps23(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	ensembl:ENSMUSG00000049517(gene)|ensembl:ENSMUST00000051955(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR005680(Ribosomal protein S23, eukaryotic/archaeal)|interpro:IPR006032(Ribosomal protein S12/S23)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P62267|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_077137.1	-	-	comment:mint	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:MWZPvSL/G45ocaxA5AXKCkDQxNU10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:O88492	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-8347295|uniprotkb:Q69Z80|uniprotkb:E9QN72|intact:MINT-4105562|uniprotkb:Q8BNV5|ensembl:ENSMUSP00000002908|ensembl:ENSMUSP00000139859	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:plin4_mouse(display_long)|uniprotkb:Kiaa1881(gene name synonym)|uniprotkb:Adipocyte protein S3-12(gene name synonym)|uniprotkb:Plin4(gene name)|psi-mi:Plin4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_065593.2|ensembl:ENSMUSG00000002831(gene)|ensembl:ENSMUST00000002908(transcript)|ensembl:ENSMUST00000190703(transcript)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR004279(Perilipin)|mint:O88492	-	-	comment:mint|function:May play a role in triacylglycerol packaging into adipocytes. May function as a coat protein involved in the biogenesis of lipid droplets	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:VIrsWg+3qqLWYOcp+l6NNgXcG2M10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q9CZS1	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-8354156|uniprotkb:Q3UAH5|intact:MINT-1869729|ensembl:ENSMUSP00000041260	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:al1b1_mouse(display_long)|uniprotkb:Aldh1b1(gene name)|psi-mi:Aldh1b1(display_short)|uniprotkb:Aldhx(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 1 member B1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_082546.1|ensembl:ENSMUSG00000035561(gene)|ensembl:ENSMUST00000044384(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:Q9CZS1|reactome:R-MMU-71384	-	-	comment:mint|function:ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:uC5KyWB4CBhkxyeLKO5Yl832ftY10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q7TSF1	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-6877235|ensembl:ENSMUSP00000076026|uniprotkb:Q7TQ60	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:dsg1b_mouse(display_long)|uniprotkb:Dsg1b(gene name)|psi-mi:Dsg1b(display_short)|uniprotkb:Dsg5(gene name synonym)|uniprotkb:Desmoglein-5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	ensembl:ENSMUSG00000061928(gene)|ensembl:ENSMUST00000076737(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q7TSF1|refseq:NP_859010.1	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:VsNieIP3TNuJAEFWaTF+KHWrXUQ10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P67778	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-298507|uniprotkb:P24142|uniprotkb:Q3UB75|uniprotkb:Q5SQG4|ensembl:ENSMUSP00000119603	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:phb_mouse(display_long)|uniprotkb:Phb(gene name)|psi-mi:Phb(display_short)|uniprotkb:B-cell receptor-associated protein 32(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	ensembl:ENSMUSG00000038845(gene)|ensembl:ENSMUST00000125172(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045471"(response to ethanol)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P67778|reactome:R-MMU-5673000|reactome:R-MMU-8949664|refseq:NP_032857.1	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:eUStcZ9Mu7+7MHr/GJXFwwJY/Fc10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:O08553	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P60335	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-309059|ensembl:ENSMUSP00000054863	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:pcbp1_mouse(display_long)|uniprotkb:Pcbp1(gene name)|psi-mi:Pcbp1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_035995.1|ensembl:ENSMUSG00000051695(gene)|ensembl:ENSMUST00000053015(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008494"(translation activator activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P60335|reactome:R-MMU-72163|reactome:R-MMU-72203	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:x72fawo4plQ+ipfqIoREIDHc2bA10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q99LF4	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-6261036|ensembl:ENSMUSP00000001834|uniprotkb:Q3UDW6|uniprotkb:Q3TI25|uniprotkb:Q3TA04	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:rtcb_mouse(display_long)|uniprotkb:Rtcb(gene name)|psi-mi:Rtcb(display_short)|uniprotkb:D10Wsu52e(gene name synonym)|uniprotkb:Focal adhesion-associated protein(gene name synonym)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	ensembl:ENSMUSG00000001783(gene)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q99LF4|ensembl:ENSMUST00000001834(transcript)|refseq:NP_663397.1	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:ISQNiLQA7DCcgBkTueMDhUHrkFQ10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P14094	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-770851|ensembl:ENSMUSP00000027863	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q9D2G2	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-773210|uniprotkb:Q3UEA0|uniprotkb:Q4FK55|uniprotkb:Q8CIE8|ensembl:ENSMUSP00000060346|ensembl:ENSMUSP00000152664	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:odo2_mouse(display_long)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:Dlst(gene name)|psi-mi:Dlst(display_short)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_084501.1|ensembl:ENSMUSG00000004789(gene)|ensembl:ENSMUST00000053811(transcript)|ensembl:ENSMUST00000221357(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:Q9D2G2|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:jyBoApRkfA3STOc5qJ01/cE2UHU10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P17751	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-444877|uniprotkb:Q3TJH2|uniprotkb:Q3UC04|uniprotkb:Q3UKG9|uniprotkb:Q64513|uniprotkb:Q9CVF9|uniprotkb:Q9CWE7|ensembl:ENSMUSP00000130858	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:tpis_mouse(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:Tpi1(gene name)|psi-mi:Tpi1(display_short)|uniprotkb:Tpi(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_033441.2|ensembl:ENSMUSG00000023456(gene)|ensembl:ENSMUST00000172132(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P17751|reactome:R-MMU-70171|reactome:R-MMU-70263	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:1+uasFpsjnuX50Ti23iaIawdp7k10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q60597	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-773541|uniprotkb:Q3UDM7|uniprotkb:Q5DTI4|uniprotkb:Q5SVX7|uniprotkb:Q5SVX9|uniprotkb:Q6PFZ2|uniprotkb:Q80Y57|uniprotkb:Q8K0K7|uniprotkb:Q8K2Z3|uniprotkb:Q8R3M2|uniprotkb:Q91WP2|ensembl:ENSMUSP00000003461|ensembl:ENSMUSP00000099090	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:odo1_mouse(display_long)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:Ogdh(gene name)|psi-mi:Ogdh(display_short)|uniprotkb:Kiaa4192(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_035086.2|refseq:XP_006514645.1|refseq:XP_006514646.1|refseq:XP_006514647.1|refseq:XP_006514648.1|refseq:NP_001239211.1|refseq:NP_001239212.1|refseq:NP_001239216.1|refseq:NP_001239217.1|refseq:XP_017169826.1|ensembl:ENSMUSG00000020456(gene)|ensembl:ENSMUST00000003461(transcript)|ensembl:ENSMUST00000101554(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q60597|rcsb pdb:3E2H|rcsb pdb:3TF7|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:6as/Sp5FTXpjU1BwjR7vJ6xcxuA10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q99P72	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-3869532|uniprotkb:Q8BHF5|uniprotkb:Q78NS1|uniprotkb:Q8BH78|uniprotkb:Q5DTK9|uniprotkb:Q7TNB7|uniprotkb:Q80W95|uniprotkb:Q8BGK7|uniprotkb:Q8BGM9|uniprotkb:Q8K290|uniprotkb:Q8K3G8|uniprotkb:Q9CTE3|ensembl:ENSMUSP00000099907	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:rtn4_mouse(display_long)|uniprotkb:Rtn4(gene name)|psi-mi:Rtn4(display_short)|uniprotkb:Kiaa0886(gene name synonym)|uniprotkb:Nogo(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_077188.1|refseq:NP_918940.1|refseq:NP_918943.1|dip:DIP-41976N|ensembl:ENSMUSG00000020458(gene)|ensembl:ENSMUST00000102843(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q99P72|rcsb pdb:2KO2|reactome:R-MMU-193634|refseq:NP_918941.1|refseq:NP_918942.1	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:+hmGWVeJPIbs6/SavXBsKK22Nqw10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P08113	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-772439|uniprotkb:P11427|ensembl:ENSMUSP00000020238	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:enpl_mouse(display_long)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Grp94(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 99(gene name synonym)|uniprotkb:Polymorphic tumor rejection antigen 1(gene name synonym)|uniprotkb:Tumor rejection antigen gp96(gene name synonym)|uniprotkb:Hsp90b1(gene name)|psi-mi:Hsp90b1(display_short)|uniprotkb:Tra-1(gene name synonym)|uniprotkb:Tra1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_035761.1|dip:DIP-32352N|ensembl:ENSMUSG00000020048(gene)|ensembl:ENSMUST00000020238(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071318"(cellular response to ATP)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P08113|reactome:R-MMU-1679131|reactome:R-MMU-3000480|reactome:R-MMU-381426|reactome:R-MMU-6785807|reactome:R-MMU-8957275	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:6hS1V+GSgQiDvTYBpzbfdL5FDcE10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q8VHX6	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-400843|uniprotkb:Q6PAI6|uniprotkb:B2RY80|uniprotkb:B9EKT2|uniprotkb:Q9JJ38|ensembl:ENSMUSP00000064163	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:flnc_mouse(display_long)|uniprotkb:Flnc(gene name)|psi-mi:Flnc(display_short)|uniprotkb:Abpl(gene name synonym)|uniprotkb:Fln2(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_001074654.1|refseq:NP_001298003.1|ensembl:ENSMUSG00000068699(gene)|mint:Q8VHX6|ensembl:ENSMUST00000065090(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-MMU-446353	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:xohwAtNkerMr1ZBB5Pi8QLYPo0Y10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P21550	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-1634301|ensembl:ENSMUSP00000072620|ensembl:ENSMUSP00000104188|ensembl:ENSMUSP00000128714	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:enob_mouse(display_long)|uniprotkb:Eno3(gene name)|psi-mi:Eno3(display_short)|uniprotkb:Eno-3(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_001129534.1|refseq:NP_031959.1|refseq:NP_001263214.1|refseq:XP_006532225.1|ensembl:ENSMUSG00000060600(gene)|ensembl:ENSMUST00000072841(transcript)|ensembl:ENSMUST00000108548(transcript)|ensembl:ENSMUST00000170716(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P21550|reactome:R-MMU-70171|reactome:R-MMU-70263	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:CN/5EMhCFqpjAxZ04UHwcLN+eRI10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q8CC27	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-9690121|uniprotkb:A2ASJ8|uniprotkb:Q8C5J5|uniprotkb:Q9CTQ6|ensembl:ENSMUSP00000110371	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:cacb2_mouse(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_001296448.1|refseq:NP_075605.1|refseq:XP_006497383.1|ensembl:ENSMUSG00000057914(gene)|ensembl:ENSMUST00000114723(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005444(Voltage-dependent calcium channel, L-type, beta-2 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035605|interpro:IPR036028|reactome:R-MMU-112308|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:v56B+tEzuDuYnl4Fri/+kK+ccSo10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P53762	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-78852|uniprotkb:Q921F3|uniprotkb:Q60661|ensembl:ENSMUSP00000099810	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:arnt_mouse(display_long)|uniprotkb:Arnt(gene name)|psi-mi:Arnt(display_short)|uniprotkb:Dioxin receptor, nuclear translocator(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_001032826.1|ensembl:ENSMUSG00000015522(gene)|ensembl:ENSMUST00000102749(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0016604"(nuclear body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|rcsb pdb:4ZP4|rcsb pdb:4ZPH|rcsb pdb:4ZPK|rcsb pdb:4ZPR|rcsb pdb:4ZQD|rcsb pdb:5NJ8|rcsb pdb:5SY5|rcsb pdb:5SY7|rcsb pdb:6E3S|rcsb pdb:6E3T|rcsb pdb:6E3U|reactome:R-MMU-1234158|reactome:R-MMU-211945|reactome:R-MMU-211976|reactome:R-MMU-211981|reactome:R-MMU-8937144|dip:DIP-280N	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:NYJuNrii1HcGy0q0T0NDNXiPiKE10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:A2ASS6	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-9672947|uniprotkb:A2ASS5|uniprotkb:A2ASS7	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:titin_mouse(display_long)|uniprotkb:Ttn(gene name)|psi-mi:Ttn(display_short)|uniprotkb:Connectin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	interpro:IPR040849|rcsb pdb:6YJ0|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR004168(PPAK motif)|interpro:IPR000719(Protein kinase, core)|interpro:IPR015129(Titin Z)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR036116|interpro:IPR036179|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0002020"(protease binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021591"(ventricular system development)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043056"(forward locomotion)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055002"(striated muscle cell development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060419"(heart growth)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:xDsiEoYt/F9ZCvYym/wgnXdwYbU10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q8BG05	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-2735601|uniprotkb:Q8BHF8|ensembl:ENSMUSP00000088298|ensembl:ENSMUSP00000107595	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:roa3_mouse(display_long)|uniprotkb:Hnrnpa3(gene name)|psi-mi:Hnrnpa3(display_short)|uniprotkb:Hnrpa3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_444493.1|refseq:NP_666242.2|refseq:NP_932758.1|ensembl:ENSMUSG00000059005(gene)|ensembl:ENSMUST00000090792(transcript)|ensembl:ENSMUST00000111964(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:Q8BG05|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:XP_011237818.1	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:KcZjXvHON9QZSqHWi4nWSDz/HtE10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:B2RXT3	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-20564766|ensembl:ENSMUSP00000154185	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:b2rxt3_mouse(display_long)|uniprotkb:Ogdhl(gene name)|psi-mi:Ogdhl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_001074599.1|refseq:XP_006519014.1|ensembl:ENSMUSG00000021913(gene)|ensembl:ENSMUST00000228529(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:LqIbHDr2Fb7M3okuFySeq9hQSDk10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P00405	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-773506|uniprotkb:Q85K21|ensembl:ENSMUSP00000080994	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:cox2_mouse(display_long)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:Mtco2(gene name)|psi-mi:Mtco2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:mt-Co2(gene name synonym)|uniprotkb:COX2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_904331.1|ensembl:ENSMUSG00000064354(gene)|ensembl:ENSMUST00000082405(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00405|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:oM1rnc+HJvDAF3+Z9fgK35b0UIw10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q7TMF3	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-2934615|ensembl:ENSMUSP00000020209|uniprotkb:Q3TIA0	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:nduac_mouse(display_long)|uniprotkb:Ndufa12(gene name)|psi-mi:Ndufa12(display_short)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	ensembl:ENSMUST00000020209(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|ensembl:ENSMUSG00000020022(gene)|refseq:NP_079827.2	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:ABTsOaXBN3GSTwTETzzEvOfVMiQ10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P38647	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q9D828	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-308969	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:q9d828_mouse(display_long)|uniprotkb:Tfg(gene name)|psi-mi:Tfg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|interpro:IPR034857|interpro:IPR033512	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:ROdjt7CfqfZJ3ELcZihI3jIUG5A10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q3TVZ1	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-20564999	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:q3tvz1_mouse(display_long)|uniprotkb:Cat(gene name)|psi-mi:Cat(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	interpro:IPR040333|interpro:IPR018028|interpro:IPR024708|interpro:IPR024711|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR020835|go:"GO:0004096"(catalase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0020037"(heme binding)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051781"(positive regulation of cell division)	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:QgslJykr39AnqC3a0XGhSm2w/qg10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:Q3TL44	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-20564964|uniprotkb:Q3UKJ1|uniprotkb:Q80W30|uniprotkb:Q8C249|ensembl:ENSMUSP00000034621|ensembl:ENSMUSP00000126555|ensembl:ENSMUSP00000127531	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:nlrx1_mouse(display_long)|uniprotkb:Nlrx1(gene name)|psi-mi:Nlrx1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_001157214.1|refseq:NP_001157215.1|refseq:NP_848507.2|ensembl:ENSMUSG00000032109(gene)|ensembl:ENSMUST00000034621(transcript)|ensembl:ENSMUST00000168499(transcript)|ensembl:ENSMUST00000169651(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0050728"(negative regulation of inflammatory response)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR007111(NACHT nucleoside triphosphatase)|interpro:IPR027417|interpro:IPR032675|reactome:R-MMU-936440	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:GPGLVS90yrD0swCbr/yfxHZfmIg10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P47738	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-2308120|ensembl:ENSMUSP00000031411	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:aldh2_mouse(display_long)|uniprotkb:Aldh2(gene name)|psi-mi:Aldh2(display_short)|uniprotkb:Ahd-1(gene name synonym)|uniprotkb:Ahd1(gene name synonym)|uniprotkb:ALDH class 2(gene name synonym)|uniprotkb:AHD-M1(gene name synonym)|uniprotkb:ALDHI(gene name synonym)|uniprotkb:ALDH-E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_033786.1|ensembl:ENSMUSG00000029455(gene)|ensembl:ENSMUST00000031411(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051287"(NAD binding)|go:"GO:0070404"(NADH binding)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P47738|reactome:R-MMU-380612|reactome:R-MMU-71384	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:C4L2qigIlQeaZH4RsNocJovkPMw10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P56695	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-20564915|uniprotkb:Q9Z276|ensembl:ENSMUSP00000048053	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:wfs1_mouse(display_long)|uniprotkb:Wfs1(gene name)|psi-mi:Wfs1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:NP_035846.1|ensembl:ENSMUSG00000039474(gene)|ensembl:ENSMUST00000043964(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001822"(kidney development)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0030141"(secretory granule)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045927"(positive regulation of growth)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050877"(nervous system process)|go:"GO:0051117"(ATPase binding)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0070628"(proteasome binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1903892"(negative regulation of ATF6-mediated unfolded protein response)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR026208|interpro:IPR026209|reactome:R-MMU-381426|reactome:R-MMU-8957275	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:c6j2JQTA5DR+mY2ILJQrd/MjY2A10090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O35219	uniprotkb:P02469	intact:EBI-9688270|uniprotkb:O35220|uniprotkb:O35221|uniprotkb:O35989	intact:EBI-6662997|ensembl:ENSMUSP00000002979|ensembl:ENSMUSP00000132778|uniprotkb:E9PXZ9	psi-mi:kcnh2_mouse(display_long)|uniprotkb:Kcnh2(gene name)|psi-mi:Kcnh2(display_short)|uniprotkb:Erg(gene name synonym)|uniprotkb:Merg1(gene name synonym)|uniprotkb:Ether-a-go-go-related gene potassium channel 1(gene name synonym)|uniprotkb:Voltage-gated potassium channel subunit Kv11.1(gene name synonym)	psi-mi:lamb1_mouse(display_long)|uniprotkb:Lamb1(gene name)|psi-mi:Lamb1(display_short)|uniprotkb:Lamb-1(gene name synonym)|uniprotkb:Lamb1-1(gene name synonym)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20564911|imex:IM-26422-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001281091.1|reactome:R-MMU-1296072|reactome:R-MMU-5576890|interpro:IPR018490|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR005821(Ion transport)|interpro:IPR003938(Potassium channel, voltage-dependent, EAG/ELK/ERG)|interpro:IPR003967(Potassium channel, voltage-dependent, ERG)|interpro:IPR001610(PAC motif)|interpro:IPR000014(PAS)|interpro:IPR000700(PAS-associated, C-terminal)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR035965|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005216"(ion channel activity)|go:"GO:0005242"(inward rectifier potassium channel activity)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035690"|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:0086011"(membrane repolarization during action potential)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097623"(potassium ion export across plasma membrane)|go:"GO:0098915"(membrane repolarization during ventricular cardiac muscle cell action potential)|go:"GO:1901379"(regulation of potassium ion transmembrane transport)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902282"(voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1902937"(inward rectifier potassium channel complex)|go:"GO:1903765"(negative regulation of potassium ion export across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)	refseq:XP_006515055.2|ensembl:ENSMUSG00000002900(gene)|ensembl:ENSMUST00000002979(transcript)|ensembl:ENSMUST00000169088(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0007611"(learning or memory)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042476"(odontogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8874081|go:"GO:0070831"(basement membrane assembly)|reactome:R-MMU-8957275|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P02469|rcsb pdb:4AQS|rcsb pdb:5MC9|refseq:XP_006515056.1	-	-	-	figure legend:Table S4, Fig. S2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/21	rogid:O1BW7H3ApM7/DfEeXjYgi+UQlJI10090	rogid:cUuVqY2JMeRrS9sDYudPy7hSIL010090	rigid:j8hDxbimOeC0xbjLL/qq2f/g6B8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P16092	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-7953898|uniprotkb:Q60830|uniprotkb:Q01736|uniprotkb:Q8CFK8|intact:MINT-2635590|uniprotkb:Q80T10|uniprotkb:E9Q2P4|uniprotkb:Q61562|uniprotkb:Q9QZM7|ensembl:ENSMUSP00000081041	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:fgfr1_mouse(display_long)|uniprotkb:Fgfr1(gene name)|psi-mi:Fgfr1(display_short)|uniprotkb:Flg(gene name synonym)|uniprotkb:Basic fibroblast growth factor receptor 1(gene name synonym)|uniprotkb:MFR(gene name synonym)|uniprotkb:Proto-oncogene c-Fgr(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:XP_011240423.1|refseq:NP_034336.2|refseq:NP_001073378.1|refseq:NP_001073377.1|refseq:XP_006509073.1|refseq:XP_006509075.1|dip:DIP-6033N|ensembl:ENSMUSG00000031565(gene)|ensembl:ENSMUST00000084027(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001759"(organ induction)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005007"(fibroblast growth factor-activated receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010863"(positive regulation of phospholipase C activity)|go:"GO:0010966"(regulation of phosphate transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0021837"(motogenic signaling involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021847"(ventricular zone neuroblast division)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030324"(lung development)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030901"(midbrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035607"(fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043583"(ear development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007435"(salivary gland morphogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR028174|interpro:IPR036179|interpro:IPR041159|mint:P16092|rcsb pdb:2CKN|reactome:R-MMU-109704|reactome:R-MMU-1257604|reactome:R-MMU-190370|reactome:R-MMU-190373|reactome:R-MMU-190374|reactome:R-MMU-445144|reactome:R-MMU-5654219|reactome:R-MMU-5654687|reactome:R-MMU-5654688|reactome:R-MMU-5654689|reactome:R-MMU-5654693|reactome:R-MMU-5654726|reactome:R-MMU-5673001|reactome:R-MMU-6811558|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048378"(regulation of lateral mesodermal cell fate specification)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048699"(generation of neurons)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051174"(regulation of phosphorus metabolic process)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060665"(regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070640"(vitamin D3 metabolic process)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0090080"(positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway)|go:"GO:0090272"(negative regulation of fibroblast growth factor production)|go:"GO:0090722"(receptor-receptor interaction)|go:"GO:1903465"(positive regulation of mitotic cell cycle DNA replication)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|go:"GO:2000546"(positive regulation of endothelial cell chemotaxis to fibroblast growth factor)|go:"GO:2000830"(positive regulation of parathyroid hormone secretion)|go:"GO:2001239"(regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016248(Fibroblast growth factor receptor)	-	-	comment:mint|function:"Receptor for basic fibroblast growth factor. A shorter form of the receptor could be a receptor for FGF1 (aFGF)"|comment:homomint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:JSLRQxD7C6jJyldtTkRE1Zn+AvE10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P14115	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8329574|uniprotkb:Q9R1X6|intact:MINT-1866600|uniprotkb:Q9CQ16|ensembl:ENSMUSP00000123410	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl27a_mouse(display_long)|uniprotkb:Rpl27a(gene name)|psi-mi:Rpl27a(display_short)|uniprotkb:L29(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_036105.2|ensembl:ENSMUSG00000046364(gene)|ensembl:ENSMUST00000143107(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001196(Ribosomal protein L15)|interpro:IPR021131|interpro:IPR027386|interpro:IPR030878|interpro:IPR036227|mint:P14115|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:8Zd8qqfOJiA99qg9FUDHq5YKNuk10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:O08528	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8344432|intact:MINT-262872|ensembl:ENSMUSP00000000642	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:hxk2_mouse(display_long)|uniprotkb:Hk2(gene name)|psi-mi:Hk2(display_short)|uniprotkb:Hexokinase type II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_038848.1|dip:DIP-41484N|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:O08528|reactome:R-MMU-70171|ensembl:ENSMUSG00000000628(gene)|ensembl:ENSMUST00000000642(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007595"(lactation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008865"(fructokinase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019158"(mannokinase activity)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001312(Hexokinase)	-	-	comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:Gm80aqf9jxkgIUOQFjicRMUq2wE10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P09542	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8345052|intact:MINT-4102127|uniprotkb:Q9CQZ2|uniprotkb:Q3UIF4|ensembl:ENSMUSP00000078715	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:myl3_mouse(display_long)|uniprotkb:Myl3(gene name)|psi-mi:Myl3(display_short)|uniprotkb:Mlc1v(gene name synonym)|uniprotkb:Mylc(gene name synonym)|uniprotkb:Myosin light chain 1, slow-twitch muscle B/ventricular isoform(gene name synonym)|uniprotkb:Myosin alkali light chain 1, ventricular/slow skeletal muscle isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_034989.1|ensembl:ENSMUSG00000059741(gene)|ensembl:ENSMUST00000079784(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016459"(myosin complex)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P09542|reactome:R-MMU-390522	-	-	function:Regulatory light chain of myosin. Does not bind calcium|comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:DB1L8qtOO7ASQnr//L+ith93jOo10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9QVP4	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8357276|uniprotkb:Q9JIE8|intact:MINT-4102168|uniprotkb:Q63977|ensembl:ENSMUSP00000099985	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:mlra_mouse(display_long)|uniprotkb:Myl7(gene name)|psi-mi:Myl7(display_short)|uniprotkb:Mylc2a(gene name synonym)|uniprotkb:Myosin regulatory light chain 7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_075017.2|ensembl:ENSMUSG00000020469(gene)|ensembl:ENSMUST00000102921(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0031672"(A band)|go:"GO:0043197"(dendritic spine)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9QVP4|reactome:R-MMU-445355	-	-	comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:leuWAVQCkKG0daoyT4BpClk7lyc10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q8K370	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8351209|uniprotkb:Q8K313|intact:MINT-1839952|uniprotkb:Q8BWQ0|ensembl:ENSMUSP00000031412|ensembl:ENSMUSP00000107400	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:acd10_mouse(display_long)|uniprotkb:Acad10(gene name)|psi-mi:Acad10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_082313.2|refseq:XP_006530521.1|refseq:XP_006530523.1|refseq:XP_006530524.1|ensembl:ENSMUSG00000029456(gene)|ensembl:ENSMUST00000031412(transcript)|ensembl:ENSMUST00000111770(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0016787"(hydrolase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR002575(Aminoglycoside phosphotransferase)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011945(Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR023198|interpro:IPR023214|interpro:IPR036250|interpro:IPR036412|interpro:IPR037069|interpro:IPR041492|interpro:IPR041726|mint:Q8K370|reactome:R-MMU-77289	-	-	comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:IsgrBdnCIl/Afx8GNhD8OrVs9aU10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P61358	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8401481|intact:MINT-1863099|ensembl:ENSMUSP00000090305|ensembl:ENSMUSP00000102870	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl27_mouse(display_long)|uniprotkb:Rpl27(gene name)|psi-mi:Rpl27(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_035419.1|refseq:XP_017170385.1|ensembl:ENSMUSG00000063316(gene)|ensembl:ENSMUST00000077856(transcript)|ensembl:ENSMUST00000107249(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61358|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P20065	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-7946048|intact:MINT-6542333|ensembl:ENSMUSP00000107797|ensembl:ENSMUSP00000107798	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:tyb4_mouse(display_long)|uniprotkb:Tmsb4x(gene name)|psi-mi:Tmsb4x(display_short)|uniprotkb:Ptmb4(gene name synonym)|uniprotkb:Tmsb4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_067253.1|refseq:XP_006528822.1|rcsb pdb:3M3N|reactome:R-MMU-114608|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|interpro:IPR001152(Thymosin beta-4)|interpro:IPR038386|mint:P20065|rcsb pdb:1T44|ensembl:ENSMUSG00000049775(gene)|ensembl:ENSMUST00000112175(transcript)|ensembl:ENSMUST00000112176(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)	-	-	function:Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase|comment:mint|function:"Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization"	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:JLA9SKFXflHenc1hfrf5hkVq5L410090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P97450	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8334028|intact:MINT-1843958|ensembl:ENSMUSP00000023608|ensembl:ENSMUSP00000109829|ensembl:ENSMUSP00000109831	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:atp5j_mouse(display_long)|uniprotkb:Atp5pf(gene name)|psi-mi:Atp5pf(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:Atp5j(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001289142.1|refseq:NP_001289143.1|refseq:NP_001289144.1|refseq:NP_001289145.1|refseq:XP_011244394.1|refseq:NP_058035.1|refseq:XP_006522939.1|refseq:XP_006522940.1|ensembl:ENSMUSG00000022890(gene)|ensembl:ENSMUST00000023608(transcript)|ensembl:ENSMUST00000114191(transcript)|ensembl:ENSMUST00000114193(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P97450|reactome:R-MMU-163210|reactome:R-MMU-8949613	-	-	function:"Mitochondrial membrane ATP synthase (F(1)F(O) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes"|comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:rIGhMjksHCjKI1cuumi5b5J8n8c10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9D881	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8333990|intact:MINT-4127563|ensembl:ENSMUSP00000038961|ensembl:ENSMUSP00000141554	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:q9d881_mouse(display_long)|uniprotkb:Cox5b-ps(gene name)|psi-mi:Cox5b-ps(display_short)|uniprotkb:Cox5b(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit 5B, mitochondrial(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_034072.2|ensembl:ENSMUSG00000061518(gene)|ensembl:ENSMUSG00000079941(gene)|ensembl:ENSMUST00000044043(transcript)|ensembl:ENSMUST00000193210(transcript)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|mint:Q9D881	-	-	comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:uNmBv2pPOF9/GjoM6yIkTGwnHmw10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9D1R9	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-7977843|intact:MINT-1857602|uniprotkb:Q497V4|ensembl:ENSMUSP00000078092|ensembl:ENSMUSP00000086614|ensembl:ENSMUSP00000142486	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl34_mouse(display_long)|uniprotkb:Rpl34(gene name)|psi-mi:Rpl34(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001186279.1|refseq:NP_001005859.1|refseq:XP_001481222.1|refseq:NP_081000.1|refseq:NP_001274510.1|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000062006(gene)|ensembl:ENSMUST00000062601(transcript)|ensembl:ENSMUST00000079085(transcript)|ensembl:ENSMUST00000196202(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR008195(Ribosomal protein L34e)|interpro:IPR018065|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689	-	-	comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:i4RSoK1rXY2RQeVjL+6iNKoD49U10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:O70468	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	-	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P62717	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8327568|uniprotkb:P11249|intact:MINT-1841289|uniprotkb:Q3TSN0|ensembl:ENSMUSP00000058368	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl18a_mouse(display_long)|uniprotkb:Rpl18a(gene name)|psi-mi:Rpl18a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_084027.1|ensembl:ENSMUSG00000045128(gene)|ensembl:ENSMUST00000054220(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:P62717|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:HMbe4GVCuVZs0/90BMnEgpOqeiA10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P35980	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-7977881|uniprotkb:Q9D987|intact:MINT-1857698|uniprotkb:Q9CQF1|ensembl:ENSMUSP00000072320|ensembl:ENSMUSP00000147816	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl18_mouse(display_long)|uniprotkb:Rpl18(gene name)|psi-mi:Rpl18(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_033103.2|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR000039(Ribosomal protein L18e)|interpro:IPR021131|interpro:IPR021132|interpro:IPR036227|mint:P35980|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|ensembl:ENSMUSG00000059070(gene)|ensembl:ENSMUST00000072503(transcript)|ensembl:ENSMUST00000210640(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|reactome:R-MMU-975957	-	-	comment:mint	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:PqTr3iXlemHDle24HNyRs+yPRJg10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9ET78	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-8350389|intact:MINT-4099221|uniprotkb:Q9ET79|uniprotkb:Q3U077|ensembl:ENSMUSP00000017961|ensembl:ENSMUSP00000105052	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:jph2_mouse(display_long)|uniprotkb:Jph2(gene name)|psi-mi:Jph2(display_short)|uniprotkb:Jp2(gene name synonym)|uniprotkb:Junctophilin type 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_067541.1|refseq:NP_001192005.1|refseq:XP_006500035.1|ensembl:ENSMUSG00000017817(gene)|ensembl:ENSMUST00000017961(transcript)|ensembl:ENSMUST00000109425(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0055024"(regulation of cardiac muscle tissue development)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)|mint:Q9ET78	-	-	comment:mint|function:Contributes to the stabilization of the junctional membrane complexes, which are common to excitable cells and mediate cross-talk between cell surface and intracellular ion channels. Probably acts by anchoring the plasma membrane and endoplasmic/sarcoplasmic reticulum. Contributes to the construction of skeletal muscle triad junctions, and plays an essential role in heart development	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:vs5IFdM0JlfwvmUcraIjKfxlfY810090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9D8N0	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-773880|uniprotkb:Q920C5|uniprotkb:Q9CRT5|uniprotkb:Q9CSU3|uniprotkb:Q9D004|ensembl:ENSMUSP00000093955	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:ef1g_mouse(display_long)|uniprotkb:eEF-1B gamma(gene name synonym)|uniprotkb:Eef1g(gene name)|psi-mi:Eef1g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0003746"(translation elongation factor activity)|dip:DIP-32124N|refseq:NP_080283.3|ensembl:ENSMUSG00000071644(gene)|ensembl:ENSMUST00000052248(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:Q9D8N0|reactome:R-MMU-156842	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:TsONpdlsFR2YmfxQmAH4ByI5/Bg10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P53395	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-773148|uniprotkb:Q3TMF5|ensembl:ENSMUSP00000000349	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:odb2_mouse(display_long)|uniprotkb:"Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase"(gene name synonym)|uniprotkb:Dihydrolipoamide branched chain transacylase(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex(gene name synonym)|uniprotkb:Dbt(gene name)|psi-mi:Dbt(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_034152.2|ensembl:ENSMUSG00000000340(gene)|ensembl:ENSMUST00000000349(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0031405"(lipoic acid binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043754"("dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity")|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P53395|reactome:R-MMU-389661|reactome:R-MMU-70895|reactome:R-MMU-9013407	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:/g3DD7tq0CE5mqTJD4ZifLuIy5E10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9Z1W8	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-11568972|uniprotkb:Q8VHY2|uniprotkb:Q32MR8|ensembl:ENSMUSP00000007340	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:at12a_mouse(display_long)|uniprotkb:Atp1al1(gene name synonym)|uniprotkb:"Non-gastric H(+)/K(+) ATPase subunit alpha"(gene name synonym)|uniprotkb:Proton pump(gene name synonym)|uniprotkb:Atp12a(gene name)|psi-mi:Atp12a(display_short)|uniprotkb:HK alpha 2(gene name synonym)|uniprotkb:"Non-gastric Na(+)/K(+) ATPase subunit alpha"(gene name synonym)|uniprotkb:Sodium pump(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_619593.2|ensembl:ENSMUSG00000022229(gene)|ensembl:ENSMUST00000007340(transcript)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006885"(regulation of pH)|go:"GO:0008900"("P-type potassium:proton transporter activity")|go:"GO:0010038"(response to metal ion)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030318|interpro:IPR036412|interpro:IPR044492|reactome:R-MMU-936837	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:UhIAcoKBKEPYftd/IFfswIMseVE10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:E9Q401	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P63017	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P62806	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-299632|ensembl:ENSMUSP00000085006|ensembl:ENSMUSP00000100029|ensembl:ENSMUSP00000100030|ensembl:ENSMUSP00000100032|ensembl:ENSMUSP00000100033|ensembl:ENSMUSP00000100036|ensembl:ENSMUSP00000100037|ensembl:ENSMUSP00000100042|ensembl:ENSMUSP00000100044|ensembl:ENSMUSP00000100048|ensembl:ENSMUSP00000100546|ensembl:ENSMUSP00000129930|ensembl:ENSMUSP00000136357|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q2M2Q5|intact:EBI-302111|uniprotkb:Q6PDS7|uniprotkb:Q811M0|uniprotkb:A0AUM5|uniprotkb:A4FUP8|uniprotkb:A4QMY0|uniprotkb:Q0VDL9|uniprotkb:Q9D0C9|uniprotkb:Q9D6Q8|uniprotkb:Q5T006	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:h4_mouse(display_long)|uniprotkb:H4c11(gene name)|psi-mi:H4c11(display_short)|uniprotkb:H4c12(gene name)|psi-mi:H4c12(display_short)|uniprotkb:H4c14(gene name)|psi-mi:H4c14(display_short)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4c3(gene name)|psi-mi:H4c3(display_short)|uniprotkb:H4c4(gene name)|psi-mi:H4c4(display_short)|uniprotkb:H4c6(gene name)|psi-mi:H4c6(display_short)|uniprotkb:H4c8(gene name)|psi-mi:H4c8(display_short)|uniprotkb:H4c9(gene name)|psi-mi:H4c9(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist1h4a(gene name synonym)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist1h4c(gene name synonym)|uniprotkb:Hist1h4d(gene name synonym)|uniprotkb:Hist1h4f(gene name synonym)|uniprotkb:Hist1h4h(gene name synonym)|uniprotkb:Hist1h4i(gene name synonym)|uniprotkb:Hist1h4j(gene name synonym)|uniprotkb:Hist1h4k(gene name synonym)|uniprotkb:Hist2h4a(gene name synonym)|uniprotkb:Hist2h4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4-53(gene name synonym)|uniprotkb:H4-12(gene name synonym)|uniprotkb:H4c1(gene name)|psi-mi:H4c1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000060093(gene)|ensembl:ENSMUSG00000060639(gene)|ensembl:ENSMUSG00000060678(gene)|ensembl:ENSMUSG00000060981(gene)|ensembl:ENSMUSG00000061482(gene)|ensembl:ENSMUSG00000064288(gene)|ensembl:ENSMUSG00000067455(gene)|ensembl:ENSMUSG00000069266(gene)|ensembl:ENSMUSG00000069274(gene)|ensembl:ENSMUSG00000069305(gene)|ensembl:ENSMUSG00000069306(gene)|ensembl:ENSMUSG00000091405(gene)|ensembl:ENSMUST00000087714(transcript)|ensembl:ENSMUST00000102964(transcript)|ensembl:ENSMUST00000102965(transcript)|ensembl:ENSMUST00000102967(transcript)|ensembl:ENSMUST00000102968(transcript)|ensembl:ENSMUST00000102971(transcript)|ensembl:ENSMUST00000102972(transcript)|ensembl:ENSMUST00000102977(transcript)|ensembl:ENSMUST00000102979(transcript)|ensembl:ENSMUST00000102983(transcript)|ensembl:ENSMUST00000104941(transcript)|ensembl:ENSMUST00000171473(transcript)|ensembl:ENSMUST00000179285(transcript)|go:"GO:0000228"(nuclear chromosome)|ensembl:ENSMUSG00000096010(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62806|rcsb pdb:1F66|rcsb pdb:1U35|rcsb pdb:2WP2|go:"GO:0003677"(DNA binding)|rcsb pdb:4AU7|rcsb pdb:4DOW|rcsb pdb:5B1L|rcsb pdb:5B1M|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-110330|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214842|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-4551638|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|refseq:NP_001182350.1|refseq:NP_291074.1|refseq:NP_694813.1|refseq:NP_783583.1|refseq:NP_783585.1|refseq:NP_783586.1|refseq:NP_783587.1|refseq:NP_783588.1|refseq:NP_835499.1|refseq:NP_835500.1|refseq:NP_835515.1|refseq:NP_835582.1|refseq:NP_835583.1|dip:DIP-45837N	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9D0M3	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-773129|uniprotkb:Q3TDC5|uniprotkb:Q3UAN2|uniprotkb:Q63ZW4|uniprotkb:Q9DCG0|ensembl:ENSMUSP00000023210	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:cy1_mouse(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 4(gene name synonym)|uniprotkb:Complex III subunit 4(gene name synonym)|uniprotkb:Complex III subunit IV(gene name synonym)|uniprotkb:Cyc1(gene name)|psi-mi:Cyc1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_079843.1|ensembl:ENSMUSG00000022551(gene)|ensembl:ENSMUST00000023210(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0020037"(heme binding)|go:"GO:0033762"(response to glucagon)|go:"GO:0046872"(metal ion binding)|interpro:IPR002326(Cytochrome c1)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR021157|interpro:IPR036909|mint:Q9D0M3|reactome:R-MMU-611105	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:tcTgdCV0NKIvzZsYmq8cBV4D5QY10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P62301	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-12600562|ensembl:ENSMUSP00000126294	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rs13_mouse(display_long)|uniprotkb:Rps13(gene name)|psi-mi:Rps13(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000090862(gene)|ensembl:ENSMUST00000170953(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_080809.1|dip:DIP-59976N	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P62897	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2308573|uniprotkb:P00009|uniprotkb:Q8C2S2|ensembl:ENSMUSP00000072829|ensembl:ENSMUSP00000124523	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:cyc_mouse(display_long)|uniprotkb:Cycs(gene name)|psi-mi:Cycs(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_031834.1|ensembl:ENSMUSG00000058927(gene)|ensembl:ENSMUSG00000063694(gene)|ensembl:ENSMUST00000073080(transcript)|ensembl:ENSMUST00000161401(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009055"(electron transfer activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|mint:P62897|reactome:R-MMU-111457|reactome:R-MMU-111458|reactome:R-MMU-111459|reactome:R-MMU-2151201|reactome:R-MMU-3299685|reactome:R-MMU-5620971|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9627069|reactome:R-MMU-9707564	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:vpo8RqJEpxq8eWPVl7eJfjlhUb010090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9CQ69	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-1219646|ensembl:ENSMUSP00000053145|ensembl:ENSMUSP00000104649	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:qcr8_mouse(display_long)|uniprotkb:Uqcrq(gene name)|psi-mi:Uqcrq(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 9.5 kDa protein(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Complex III subunit 8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_079628.1|refseq:NP_001313543.1|ensembl:ENSMUSG00000044894(gene)|ensembl:ENSMUST00000061326(transcript)|ensembl:ENSMUST00000109021(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0021539"(subthalamus development)|go:"GO:0021548"(pons development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030901"(midbrain development)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004205(UcrQ)|interpro:IPR036642|mint:Q9CQ69|reactome:R-MMU-611105	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:D31g2yr7auK53pPni0uZ10drZrY10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9DB77	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-773760|uniprotkb:Q8BK11|uniprotkb:Q9CVK7|ensembl:ENSMUSP00000033176	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:qcr2_mouse(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:Uqcrc2(gene name)|psi-mi:Uqcrc2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_080175.1|ensembl:ENSMUSG00000030884(gene)|ensembl:ENSMUST00000033176(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006508"(proteolysis)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:Q9DB77|reactome:R-MMU-611105	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:CTpkPoAK0EWa6sxA5LJY0srVn/s10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P14733	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-445247|uniprotkb:Q61791|ensembl:ENSMUSP00000025486	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:lmnb1_mouse(display_long)|uniprotkb:Lmnb1(gene name)|psi-mi:Lmnb1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_034851.2|mint:P14733|reactome:R-MMU-9035034|reactome:R-MMU-2559584|reactome:R-MMU-352238|reactome:R-MMU-4419969|reactome:R-MMU-9013405|ensembl:ENSMUSG00000024590(gene)|ensembl:ENSMUST00000025486(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1904609"(cellular response to monosodium L-glutamate)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|go:"GO:0003690"(double-stranded DNA binding)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:/Mo4KS6v6KhDRlYgD5CVVVtWVD810090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P56480	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:O55143	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-770763|uniprotkb:Q9R2A9|uniprotkb:Q9WUT5|ensembl:ENSMUSP00000031423|ensembl:ENSMUSP00000135935	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:at2a2_mouse(display_long)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)|uniprotkb:Atp2a2(gene name)|psi-mi:Atp2a2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001103610.1|refseq:NP_033852.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0006996"(organelle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O55143|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000029467(gene)|ensembl:ENSMUST00000031423(transcript)|ensembl:ENSMUST00000179939(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:LJG8hpHG2pO9ePikEKYbhsuCeRI10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q6ZWN5	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-12600852|ensembl:ENSMUSP00000006496|ensembl:ENSMUSP00000104265|uniprotkb:Q3UBF1|uniprotkb:Q8K2D1	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rs9_mouse(display_long)|uniprotkb:Rps9(gene name)|psi-mi:Rps9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000006333(gene)|ensembl:ENSMUST00000006496(transcript)|ensembl:ENSMUST00000108625(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_084043.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P14094	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-770851|ensembl:ENSMUSP00000027863	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q3TSA5	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20564594	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:q3tsa5_mouse(display_long)|uniprotkb:Pabpc4(gene name)|psi-mi:Pabpc4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR036053|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:WFmYVUqfxdBLyC5d6vIUVI4vjbg10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9CPU4	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2935061|uniprotkb:Q3UXC5|uniprotkb:Q9D834|ensembl:ENSMUSP00000028005	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:mgst3_mouse(display_long)|uniprotkb:Mgst3(gene name)|psi-mi:Mgst3(display_short)|uniprotkb:Glutathione peroxidase MGST3(gene name synonym)|uniprotkb:Microsomal glutathione S-transferase III(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0004464"(leukotriene-C4 synthase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001129("Membrane-associated, eicosanoid and glutathione metabolism (MAPEG)")|interpro:IPR023352|reactome:R-MMU-156590|reactome:R-MMU-5423646|go:"GO:0004364"(glutathione transferase activity)|ensembl:ENSMUSG00000026688(gene)|ensembl:ENSMUST00000028005(transcript)|refseq:NP_079845.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:uxWRd47vtmR9RmuPoh7cfAmDgvs10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q64478	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-11517726|uniprotkb:A2RTP6|uniprotkb:Q3TYR6|ensembl:ENSMUSP00000153277	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:h2b1h_mouse(display_long)|uniprotkb:H2bc9(gene name)|psi-mi:H2bc9(display_short)|uniprotkb:H2B-clustered histone 9(gene name synonym)|uniprotkb:Hist1h2bh(gene name synonym)|uniprotkb:h2B-221(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_835504.1|ensembl:ENSMUSG00000114456(gene)|ensembl:ENSMUST00000224359(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|reactome:R-MMU-110330|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214847|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8866654|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|reactome:R-MMU-606279	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:T5y9enRIn1oPv/tJqXcOU42pnXY10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9D2G2	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-773210|uniprotkb:Q3UEA0|uniprotkb:Q4FK55|uniprotkb:Q8CIE8|ensembl:ENSMUSP00000060346|ensembl:ENSMUSP00000152664	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:odo2_mouse(display_long)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:Dlst(gene name)|psi-mi:Dlst(display_short)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_084501.1|ensembl:ENSMUSG00000004789(gene)|ensembl:ENSMUST00000053811(transcript)|ensembl:ENSMUST00000221357(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:Q9D2G2|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:jyBoApRkfA3STOc5qJ01/cE2UHU10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q60597	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-773541|uniprotkb:Q3UDM7|uniprotkb:Q5DTI4|uniprotkb:Q5SVX7|uniprotkb:Q5SVX9|uniprotkb:Q6PFZ2|uniprotkb:Q80Y57|uniprotkb:Q8K0K7|uniprotkb:Q8K2Z3|uniprotkb:Q8R3M2|uniprotkb:Q91WP2|ensembl:ENSMUSP00000003461|ensembl:ENSMUSP00000099090	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:odo1_mouse(display_long)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:Ogdh(gene name)|psi-mi:Ogdh(display_short)|uniprotkb:Kiaa4192(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_035086.2|refseq:XP_006514645.1|refseq:XP_006514646.1|refseq:XP_006514647.1|refseq:XP_006514648.1|refseq:NP_001239211.1|refseq:NP_001239212.1|refseq:NP_001239216.1|refseq:NP_001239217.1|refseq:XP_017169826.1|ensembl:ENSMUSG00000020456(gene)|ensembl:ENSMUST00000003461(transcript)|ensembl:ENSMUST00000101554(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q60597|rcsb pdb:3E2H|rcsb pdb:3TF7|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:6as/Sp5FTXpjU1BwjR7vJ6xcxuA10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9CQ62	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-299499|ensembl:ENSMUSP00000029877|uniprotkb:Q9DCI7	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:decr_mouse(display_long)|uniprotkb:Decr1(gene name)|psi-mi:Decr1(display_short)|uniprotkb:2,4-dienoyl-CoA reductase [NADPH](gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000028223(gene)|ensembl:ENSMUST00000029877(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008670"("2,4-dienoyl-CoA reductase (NADPH) activity")|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902494"(catalytic complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q9CQ62|reactome:R-MMU-77288|go:"GO:0042802"(identical protein binding)|go:"GO:0070402"(NADPH binding)|refseq:NP_080448.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:Bh2PIoAhcHP1Sek3ELKceJj2xF410090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q8BGH2	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2934811|ensembl:ENSMUSP00000023071|uniprotkb:Q3TIL3|uniprotkb:Q3TTG7|uniprotkb:Q3TWD3	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:sam50_mouse(display_long)|uniprotkb:Samm50(gene name)|psi-mi:Samm50(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000022437(gene)|ensembl:ENSMUST00000023071(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0042407"(cristae formation)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|mint:Q8BGH2|reactome:R-MMU-9013404|refseq:NP_848729.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:OWxecVBGU7/ayT7jqSrqeKmr5fw10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9CQQ7	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2935050|ensembl:ENSMUSP00000113022	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:at5f1_mouse(display_long)|uniprotkb:Atp5pb(gene name)|psi-mi:Atp5pb(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:Atp5f1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000000563(gene)|ensembl:ENSMUST00000118209(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:Q9CQQ7|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_033855.2	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:g22oBc1YXUjxPlMIN/TbpQrIXEg10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q791V5	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-775885|ensembl:ENSMUSP00000121851|uniprotkb:Q3TPS5|uniprotkb:Q99LZ6|uniprotkb:Q9D060|uniprotkb:Q9D7Y2|uniprotkb:Q9QZP3	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:mtch2_mouse(display_long)|uniprotkb:Mtch2(gene name)|psi-mi:Mtch2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0071478"(cellular response to radiation)|go:"GO:0090152"(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|ensembl:ENSMUSG00000027282(gene)|ensembl:ENSMUST00000136872(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR018108|interpro:IPR023395|mint:Q791V5|refseq:NP_062732.1|refseq:NP_001304170.1|refseq:NP_001304171.1|refseq:NP_001304172.1|refseq:NP_001304173.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:5TT13uYcx21wiKjuQc4tynZ31Ac10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9WUR2	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2794295|uniprotkb:Q99M61|uniprotkb:Q9D785|ensembl:ENSMUSP00000131735	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:eci2_mouse(display_long)|uniprotkb:Eci2(gene name)|psi-mi:Eci2(display_short)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Peci(gene name synonym)|uniprotkb:Peroxisomal 3,2-trans-enoyl-CoA isomerase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001103801.1|refseq:NP_035998.2|refseq:XP_006516736.1|refseq:XP_006516737.1|refseq:XP_006516738.1|refseq:XP_006516739.1|refseq:XP_006516740.1|ensembl:ENSMUSG00000021417(gene)|ensembl:ENSMUST00000171229(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR001753(Crotonase, core)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR022408|interpro:IPR029045|interpro:IPR035984|mint:Q9WUR2|reactome:R-MMU-390247|reactome:R-MMU-9033241|go:"GO:0006635"(fatty acid beta-oxidation)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:nHPcS0mXXHwtPjuxHZLEOsf99sk10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q60930	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-444578|ensembl:ENSMUSP00000022293|uniprotkb:Q78MH6|uniprotkb:Q99L98	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:vdac2_mouse(display_long)|uniprotkb:Voltage-dependent anion-selective channel protein 6(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)|uniprotkb:Vdac2(gene name)|psi-mi:Vdac2(display_short)|uniprotkb:Vdac6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_035825.1|ensembl:ENSMUSG00000021771(gene)|ensembl:ENSMUST00000022293(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:Q60930|reactome:R-MMU-5689880	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:ApSD4TVlagQ1QHePbOZw7J5rmzQ10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P62242	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-351820|uniprotkb:P09058|uniprotkb:Q8C2G6|ensembl:ENSMUSP00000099757	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rs8_mouse(display_long)|uniprotkb:Rps8(gene name)|psi-mi:Rps8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_033124.1|ensembl:ENSMUSG00000047675(gene)|ensembl:ENSMUST00000102696(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62242|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:3rpCBdQyRWR+TCKnupbnCp30jKE10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q01768	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-642573|ensembl:ENSMUSP00000021217|ensembl:ENSMUSP00000103476	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:ndkb_mouse(display_long)|uniprotkb:nm23-M2(gene name synonym)|uniprotkb:P18(gene name synonym)|uniprotkb:Nme2(gene name)|psi-mi:Nme2(display_short)|uniprotkb:Histidine protein kinase NDKB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001070997.1|refseq:NP_032731.1|ensembl:ENSMUSG00000020857(gene)|ensembl:ENSMUST00000021217(transcript)|ensembl:ENSMUST00000072566(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1901363"(heterocyclic compound binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:Q01768|reactome:R-MMU-499943|reactome:R-MMU-6798695	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:AJ1Depmyy9zwTEUOZMRO7TKPd1k10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q3V384	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565389|uniprotkb:Q5EBH5|uniprotkb:Q8K1E9|ensembl:ENSMUSP00000036149	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:afg1l_mouse(display_long)|uniprotkb:Lactation elevated protein 1(gene name synonym)|uniprotkb:Afg1l(gene name)|psi-mi:Afg1l(display_short)|uniprotkb:Lace1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_665686.2|ensembl:ENSMUSG00000038302(gene)|ensembl:ENSMUST00000041024(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|interpro:IPR005654(AFG1-like ATPase)|interpro:IPR027417	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:ucW93YB8cj+s2L/5VeldLdnEm4s10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9CQ75	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2255517|uniprotkb:Q9WUB2|ensembl:ENSMUSP00000014438	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:ndua2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym)|uniprotkb:Ndufa2(gene name)|psi-mi:Ndufa2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_035015.2|ensembl:ENSMUSG00000014294(gene)|ensembl:ENSMUST00000014438(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|mint:Q9CQ75|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:Z2rI9xDggf8OO321yyMsskocTYM10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P62855	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-6260985|ensembl:ENSMUSP00000026420|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:P02383	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rs26_mouse(display_long)|uniprotkb:Rps26(gene name)|psi-mi:Rps26(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000025362(gene)|ensembl:ENSMUST00000026420(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|mint:P62855|refseq:NP_038793.2	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9DCX2	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2255503|uniprotkb:B1ASE1|uniprotkb:Q542H1|uniprotkb:Q7M0I0|uniprotkb:Q91YK9|ensembl:ENSMUSP00000046256|ensembl:ENSMUSP00000086072|ensembl:ENSMUSP00000102147|ensembl:ENSMUSP00000137071	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:atp5h_mouse(display_long)|uniprotkb:Atp5pd(gene name)|psi-mi:Atp5pd(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:Atp5h(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_082138.1|refseq:XP_006534317.1|ensembl:ENSMUSG00000034566(gene)|ensembl:ENSMUST00000043931(transcript)|ensembl:ENSMUST00000073791(transcript)|ensembl:ENSMUST00000106537(transcript)|ensembl:ENSMUST00000180072(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1901653"(cellular response to peptide)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:Q9DCX2|reactome:R-MMU-163210|reactome:R-MMU-8949613	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:OJ9KqZtJ9IxSLv0aHm0DcOI9d7w10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9CZM2	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2526843|uniprotkb:Q9CWI5|ensembl:ENSMUSP00000078388|ensembl:ENSMUSP00000079163|ensembl:ENSMUSP00000098362|ensembl:ENSMUSP00000108217	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl15_mouse(display_long)|uniprotkb:Rpl15(gene name)|psi-mi:Rpl15(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_079862.1|ensembl:ENSMUSG00000012405(gene)|ensembl:ENSMUST00000079419(transcript)|ensembl:ENSMUST00000080281(transcript)|ensembl:ENSMUST00000100799(transcript)|ensembl:ENSMUST00000112598(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:Q9CZM2|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:XP_006518143.1|refseq:XP_006518144.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:wllGpJicgC5uwkZV6e4QRwDcrBo10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:A8DUV1	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565375	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:a8duv1_mouse(display_long)|uniprotkb:Hbat1(gene name)|psi-mi:Hbat1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	interpro:IPR000971(Globin, subset)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:qqaIfXJKAmDOpzUsRqXu8GYyldk10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q3T9U9	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565365	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:q3t9u9_mouse(display_long)|uniprotkb:Rpl3(gene name)|psi-mi:Rpl3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	interpro:IPR000597(Ribosomal protein L3)|interpro:IPR019926|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:Tjep/PEYfN7xiSbtpWZjIlhZTEU10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P14206	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P62204	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-397460|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q3TEH7|uniprotkb:Q3THK5|uniprotkb:Q3U6Z5|uniprotkb:Q3U7C7|uniprotkb:Q498A3|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q8BNC9|uniprotkb:Q91VQ9|uniprotkb:Q9D6G4|dip:DIP-31550N|uniprotkb:P0DP26|uniprotkb:P0DP28	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:calm_mouse(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:Cam(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	rcsb pdb:3WFN|rcsb pdb:4HEX|go:"GO:0005509"(calcium ion binding)|go:"GO:0000922"(spindle pole)|refseq:NP_031615.1|refseq:NP_031616.1|refseq:NP_033920.1|rcsb pdb:2IX7|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:2DFS|refseq:NP_001300863.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0043388"(positive regulation of DNA binding)|reactome:R-MMU-2672351|reactome:R-MMU-418359|reactome:R-MMU-425561|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0005829"(cytosol)|reactome:R-MMU-8876725|rcsb pdb:4E50|rcsb pdb:4E53|go:"GO:0061024"(membrane organization)|rcsb pdb:4ZLK|reactome:R-MMU-1445148|reactome:R-MMU-5576892|ensembl:ENSMUST00000019514|ensembl:ENSMUST00000040440|ensembl:ENSMUST00000110082|reactome:R-MMU-111932|reactome:R-MMU-111933|reactome:R-MMU-111957|reactome:R-MMU-114608|reactome:R-MMU-1474151|reactome:R-MMU-1855204|reactome:R-MMU-203615|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-442717|reactome:R-MMU-442729|reactome:R-MMU-442745|reactome:R-MMU-442982|reactome:R-MMU-445355|reactome:R-MMU-451308|reactome:R-MMU-5607763|reactome:R-MMU-5626467|reactome:R-MMU-5218920|reactome:R-MMU-5627123|reactome:R-MMU-5673001|reactome:R-MMU-70221|ensembl:ENSMUSG00000001175|ensembl:ENSMUSG00000019370|ensembl:ENSMUSG00000036438|ensembl:ENSMUSP00000019514|ensembl:ENSMUSP00000048857|ensembl:ENSMUSP00000105709|reactome:R-MMU-2514859|reactome:R-MMU-163615|go:"GO:0034704"(calcium channel complex)|go:"GO:0005813"(centrosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030426"(growth cone)|go:"GO:0005634"(nucleus)|go:"GO:0030017"(sarcomere)|go:"GO:0005876"(spindle microtubule)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0002027"(regulation of heart rate)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|go:"GO:0021762"(substantia nigra development)|rcsb pdb:1UP5|go:"GO:1902494"(catalytic complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0043209"(myelin sheath)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031432"(titin binding)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|reactome:R-MMU-2025928|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0051300"(spindle pole body organization)|interpro:IPR039030	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:tTYcOd9bOh211njZVz7cYVybAMQ10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P53026	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-773918	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl10a_mouse(display_long)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Rpl10a(gene name)|psi-mi:Rpl10a(display_short)|uniprotkb:Nedd6(gene name synonym)|uniprotkb:Nedd-6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	interpro:IPR028364|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR023673|interpro:IPR023674|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|mint:P53026|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:hL4G0HJQ8H6+nUIVFXxy0Y1QXnQ10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P58771	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-298478|uniprotkb:P02558|uniprotkb:P19354|uniprotkb:P46902|uniprotkb:P99034|ensembl:ENSMUSP00000109315	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:tpm1_mouse(display_long)|uniprotkb:Tpm-1(gene name synonym)|uniprotkb:Tpma(gene name synonym)|uniprotkb:Tpm1(gene name)|psi-mi:Tpm1(display_short)|uniprotkb:Tropomyosin-1(gene name synonym)|uniprotkb:Alpha-tropomyosin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000032366(gene)|ensembl:ENSMUST00000113685(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003065"(positive regulation of heart rate by epinephrine)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031529"(ruffle organization)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051693"(actin filament capping)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000533(Tropomyosin)|mint:P58771|rcsb pdb:7NEP|reactome:R-MMU-390522|reactome:R-MMU-445355|go:"GO:0003779"(actin binding)|refseq:NP_001157720.1|refseq:NP_077745.2|dip:DIP-300N	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:d/imATvus0XZvr7i//2MtbXZ7Pw10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9ERS2	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2934630|ensembl:ENSMUSP00000105796|uniprotkb:Q9DC98|uniprotkb:Q9DCA1	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:nduad_mouse(display_long)|uniprotkb:Ndufa13(gene name)|psi-mi:Ndufa13(display_short)|uniprotkb:Grim19(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000036199(gene)|ensembl:ENSMUST00000110167(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9ERS2|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_075801.1|refseq:XP_017168432.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:wgq95IYdQM3hRpOywBXA0Axqil010090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9QXX4	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-775952|uniprotkb:Q9CZF6|uniprotkb:Q9DCF5|ensembl:ENSMUSP00000015256|ensembl:ENSMUSP00000139571	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:cmc2_mouse(display_long)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)|uniprotkb:Slc25a13(gene name)|psi-mi:Slc25a13(display_short)|uniprotkb:Aralar2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001171043.1|refseq:NP_056644.1|ensembl:ENSMUSG00000015112(gene)|ensembl:ENSMUST00000015256(transcript)|ensembl:ENSMUST00000188414(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9QXX4|reactome:R-MMU-70263|reactome:R-MMU-8963693	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:c7qSgch4lV/J3PGriiqzNknznm010090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q06185	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-6666496|ensembl:ENSMUSP00000051222|uniprotkb:P70342	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:atp5i_mouse(display_long)|uniprotkb:Atp5me(gene name)|psi-mi:Atp5me(display_short)|uniprotkb:Atp5i(gene name synonym)|uniprotkb:Atp5k(gene name synonym)|uniprotkb:Lfm-1(gene name synonym)|uniprotkb:Lfm1(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:Q06185|reactome:R-MMU-163210|reactome:R-MMU-8949613|ensembl:ENSMUSG00000050856(gene)|ensembl:ENSMUST00000049628(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|refseq:NP_031533.2	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:1hl0GhfM23wEB+OjR4PbmxMdNnQ10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P19123	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-299247|ensembl:ENSMUSP00000131991	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:tnnc1_mouse(display_long)|uniprotkb:Tnnc1(gene name)|psi-mi:Tnnc1(display_short)|uniprotkb:Tncc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000091898(gene)|ensembl:ENSMUST00000169169(transcript)|go:"GO:0002086"(diaphragm contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005861"(troponin complex)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0010038"(response to metal ion)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0031013"(troponin I binding)|go:"GO:0031014"(troponin T binding)|go:"GO:0032972"(regulation of muscle filament sliding speed)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P19123|rcsb pdb:6KLT|rcsb pdb:6KLU|reactome:R-MMU-390522|go:"GO:0043292"(contractile fiber)|refseq:NP_033419.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:sxUY0VTOyvGAvAbm1MDahk7Ejd010090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P50247	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-646982|uniprotkb:Q91WF1|ensembl:ENSMUSP00000061851|ensembl:ENSMUSP00000127198	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:sahh_mouse(display_long)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:Liver copper-binding protein(gene name synonym)|uniprotkb:CUBP(gene name synonym)|uniprotkb:Ahcy(gene name)|psi-mi:Ahcy(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_057870.3|refseq:NP_001291457.1|ensembl:ENSMUSG00000027597(gene)|ensembl:ENSMUSG00000048087(gene)|ensembl:ENSMUST00000054607(transcript)|ensembl:ENSMUST00000059524(transcript)|go:"GO:0002439"(chronic inflammatory response to antigenic stimulus)|go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0019510"(S-adenosylhomocysteine catabolic process)|go:"GO:0030554"(adenyl nucleotide binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042470"(melanosome)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0051287"(NAD binding)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:P50247|rcsb pdb:5AXA|rcsb pdb:5AXB|rcsb pdb:5AXC|reactome:R-MMU-156581|reactome:R-MMU-1614635|rcsb pdb:5AXD	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:3huaZIY/NrWyXH/kTaMriwT35A410090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P12787	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2934751|ensembl:ENSMUSP00000000090|uniprotkb:Q9D2W1	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:cox5a_mouse(display_long)|uniprotkb:Cox5a(gene name)|psi-mi:Cox5a(display_short)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0043209"(myelin sheath)|go:"GO:0046872"(metal ion binding)|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P12787|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|ensembl:ENSMUSG00000000088(gene)|ensembl:ENSMUST00000000090(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_031773.2	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:TSqMPwzrYDOAB4IRLwU8EcFKdY010090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P35441	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-6171593	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:tsp1_mouse(display_long)|uniprotkb:Thbs1(gene name)|psi-mi:Thbs1(display_short)|uniprotkb:Tsp1(gene name synonym)|uniprotkb:Glycoprotein G(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002581"(negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0002605"(negative regulation of dendritic cell antigen processing and presentation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0043236"(laminin binding)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070052"(collagen V binding)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030141"(secretory granule)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|reactome:R-MMU-114608|reactome:R-MMU-186797|reactome:R-MMU-216083|reactome:R-MMU-5173214|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016477"(cell migration)|interpro:IPR001881(EGF-like calcium-binding)|mint:P35441|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR017897|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR028499|interpro:IPR028974|interpro:IPR036383	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:0j9TPpvxNW9TNMFkFCNo+9wD3fA10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:A8DV41	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565352	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:a8dv41_mouse(display_long)|uniprotkb:Hbbt2(gene name)|psi-mi:Hbbt2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	interpro:IPR000971(Globin, subset)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR002337(Haemoglobin, beta)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:9H7wNeKDK8EBC2AgKGETgZ3NwLM10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P51667	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-298593|uniprotkb:Q6P8P4|uniprotkb:Q9QVP3|ensembl:ENSMUSP00000014080|ensembl:ENSMUSP00000107380	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:mlrv_mouse(display_long)|uniprotkb:Myosin light chain 2, slow skeletal/ventricular muscle isoform(gene name synonym)|uniprotkb:Myl2(gene name)|psi-mi:Myl2(display_short)|uniprotkb:Mylpc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0043292"(contractile fiber)|go:"GO:0055001"(muscle cell development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098735"(positive regulation of the force of heart contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P51667|reactome:R-MMU-390522|go:"GO:0042694"(muscle cell fate specification)|ensembl:ENSMUSG00000013936(gene)|ensembl:ENSMUST00000014080(transcript)|ensembl:ENSMUST00000111751(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007507"(heart development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031672"(A band)|refseq:NP_034991.3	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:Skjc00qypNcSdNKEoHRPei83rUY10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P49817	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-1161338|uniprotkb:Q8C1X7|uniprotkb:Q8CBP4|uniprotkb:Q9QYH3|uniprotkb:Q9QYH4|ensembl:ENSMUSP00000007799|ensembl:ENSMUSP00000111116	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:cav1_mouse(display_long)|uniprotkb:Cav1(gene name)|psi-mi:Cav1(display_short)|uniprotkb:Cav(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	ensembl:ENSMUSG00000007655(gene)|ensembl:ENSMUST00000007799(transcript)|ensembl:ENSMUST00000115456(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0042060"(wound healing)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0052547"(regulation of peptidase activity)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070836"(caveola assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090398"(cellular senescence)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001258"(negative regulation of cation channel activity)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|interpro:IPR018361|mint:P49817|reactome:R-MMU-203615|reactome:R-MMU-203641|reactome:R-MMU-210991|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|reactome:R-MMU-4641262|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|reactome:R-MMU-9696273|reactome:R-MMU-9696264|refseq:NP_001229993.1|refseq:NP_031642.1|refseq:XP_006505037.1|refseq:XP_006505038.1|refseq:XP_006505039.1|dip:DIP-35140N	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:63vvAW/JPjuk8ZV3ZqoYdsy4umQ10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9QY23	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565315|uniprotkb:A4QPD8|uniprotkb:Q0VGP3|uniprotkb:Q3KQL7|ensembl:ENSMUSP00000069961	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:pkp3_mouse(display_long)|uniprotkb:Pkp3(gene name)|psi-mi:Pkp3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001156396.1|refseq:NP_062736.2|ensembl:ENSMUSG00000054065(gene)|ensembl:ENSMUST00000066873(transcript)|go:"GO:0002159"(desmosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028434|interpro:IPR028435|reactome:R-MMU-6805567|reactome:R-MMU-6809371	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:Qq/hrdQkMF4cc9QR2TtSprNLQCE10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:A1IGX6	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565311	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:a1igx6_mouse(display_long)|uniprotkb:dsg4(gene name)|psi-mi:dsg4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	-	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:5OytYwmMK4XjALbm3t2qvwfkyvw10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P47911	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-773947|uniprotkb:Q6P5I2|uniprotkb:Q925C3|ensembl:ENSMUSP00000031617	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl6_mouse(display_long)|uniprotkb:TAX-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Rpl6(gene name)|psi-mi:Rpl6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_035420.2|refseq:XP_006530290.1|ensembl:ENSMUSG00000029614(gene)|ensembl:ENSMUST00000031617(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:P47911|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:rm/g3X/3zoauNoUW6K4M43n8e4810090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q80TN1	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2933616	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:q80tn1_mouse(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)|uniprotkb:mKIAA0968(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR032710	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:ZM8ubS1DGmAavt+X7DT9zthvkn410090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q62407	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565270|uniprotkb:Q3TPH8|uniprotkb:Q6P5V1|uniprotkb:Q80TF7|uniprotkb:Q80ZN0|uniprotkb:Q8BZF4|uniprotkb:Q9EQJ5	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:speg_mouse(display_long)|uniprotkb:Aortic preferentially expressed protein 1(gene name synonym)|uniprotkb:Speg(gene name)|psi-mi:Speg(display_short)|uniprotkb:Apeg1(gene name synonym)|uniprotkb:Kiaa1297(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001078839.1|refseq:NP_001078840.1|refseq:NP_001166948.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR036116|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR015726(Serine/threonine protein kinase, striated muscle)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060541"(respiratory system development)|go:"GO:0072359"(circulatory system development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:T1Eyb7kspnNUOYfrHfYJmdMQ0GQ10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P86048	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565247|ensembl:ENSMUSP00000100795	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl10l_mouse(display_long)|uniprotkb:Rpl10l(gene name)|psi-mi:Rpl10l(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001156405.1|ensembl:ENSMUSG00000060499(gene)|ensembl:ENSMUST00000081908(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:V0iyRfar4eREk2keUo5HlgzUgkI10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P47963	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-445016|uniprotkb:Q9CRZ9|uniprotkb:Q9DCH1|ensembl:ENSMUSP00000000756	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl13_mouse(display_long)|uniprotkb:A52(gene name synonym)|uniprotkb:Rpl13(gene name)|psi-mi:Rpl13(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_058018.2|ensembl:ENSMUSG00000000740(gene)|ensembl:ENSMUST00000000756(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0060348"(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P47963|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0022626"(cytosolic ribosome)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:s4+tKYYhhfFHM5TZCNIgbE2hQds10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P14148	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-445010|uniprotkb:Q80UR0|ensembl:ENSMUSP00000071616	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl7_mouse(display_long)|uniprotkb:Rpl7(gene name)|psi-mi:Rpl7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_035421.2|ensembl:ENSMUSG00000043716(gene)|ensembl:ENSMUST00000058437(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P14148|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:3mgKWwOhV0qZfTQwfsTkqol4iIY10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P19253	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-445023|ensembl:ENSMUSP00000115722	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl13a_mouse(display_long)|uniprotkb:Transplantation antigen P198(gene name synonym)|uniprotkb:Tum-P198 antigen(gene name synonym)|uniprotkb:Rpl13a(gene name)|psi-mi:Rpl13a(display_short)|uniprotkb:P198(gene name synonym)|uniprotkb:Tstap198-7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_033464.2|ensembl:ENSMUSG00000074129(gene)|ensembl:ENSMUST00000150350(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042592"(homeostatic process)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1901194"(negative regulation of formation of translation preinitiation complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005755(Ribosomal protein L13, eukaryotic/archaeal)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR023563|interpro:IPR036899|mint:P19253|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|rcsb pdb:6SWA	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:OHHQbay1m62ZSGYnKANekTh+C5Q10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P62889	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-4285659|uniprotkb:P04645|ensembl:ENSMUSP00000009039|ensembl:ENSMUSP00000106014	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl30_mouse(display_long)|uniprotkb:Rpl30(gene name)|psi-mi:Rpl30(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001156957.1|refseq:NP_033109.1|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62889|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000058600(gene)|ensembl:ENSMUST00000009039(transcript)|ensembl:ENSMUST00000079735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0014069"(postsynaptic density)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:xR9LwYg6N7m9njT1pYumOPKZVu410090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9CWK0	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-4286270	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:q9cwk0_mouse(display_long)|uniprotkb:Rpl14(gene name)|psi-mi:Rpl14(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	interpro:IPR002784(Ribosomal protein L14)|interpro:IPR014722(Translation protein SH3-like, subgroup)|mint:Q9CWK0|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR039660|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR041985	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:7cOC2RFf58l9cMSA2Y4a4UjQ4hg10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P51637	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-298576|ensembl:ENSMUSP00000074922	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9D273	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565224|uniprotkb:Q3UFL6|uniprotkb:Q8CBZ0|uniprotkb:Q8VBZ4|ensembl:ENSMUSP00000031560	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:mmab_mouse(display_long)|uniprotkb:"Cob(II)alamin adenosyltransferase"(gene name synonym)|uniprotkb:"Cob(II)yrinic acid a,c-diamide adenosyltransferase"(gene name synonym)|uniprotkb:Cobinamide/cobalamin adenosyltransferase(gene name synonym)|uniprotkb:Methylmalonic aciduria type B homolog(gene name synonym)|uniprotkb:Mmab(gene name)|psi-mi:Mmab(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_084232.1|ensembl:ENSMUSG00000029575(gene)|ensembl:ENSMUST00000031560(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0008817"("cob(I)yrinic acid a,c-diamide adenosyltransferase activity")|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0031419"(cobalamin binding)|interpro:IPR016030("Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like")|interpro:IPR029499|interpro:IPR036451|reactome:R-MMU-196741	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:YCF9ngsegdBTULorpZWAqaLm4qs10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q6PHZ2	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-2308458|uniprotkb:Q3UF87|uniprotkb:Q3UQH9|uniprotkb:Q5DTK4|uniprotkb:Q8CAC5|uniprotkb:Q9CZE2|ensembl:ENSMUSP00000143504	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:kcc2d_mouse(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001020609.1|refseq:NP_076302.1|refseq:NP_001020610.1|refseq:NP_001280592.1|refseq:NP_001280593.1|dip:DIP-47638N|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000199300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q6PHZ2|rcsb pdb:6BAB|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P62918	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-6910319|ensembl:ENSMUSP00000004072|ensembl:ENSMUSP00000155657|uniprotkb:P25120|uniprotkb:Q3V288	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:rl8_mouse(display_long)|uniprotkb:Rpl8(gene name)|psi-mi:Rpl8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62918|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000003970(gene)|ensembl:ENSMUST00000004072(transcript)|ensembl:ENSMUST00000229183(transcript)|go:"GO:0002181"(cytoplasmic translation)|refseq:NP_036183.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q9ET80	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565195|uniprotkb:Q0VB08|uniprotkb:Q9EQZ3|ensembl:ENSMUSP00000039072	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:jph1_mouse(display_long)|uniprotkb:Junctophilin type 1(gene name synonym)|uniprotkb:Jph1(gene name)|psi-mi:Jph1(display_short)|uniprotkb:Jp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_065629.1|refseq:XP_011236698.1|refseq:XP_011236699.1|refseq:XP_011236700.1|refseq:XP_011236701.1|ensembl:ENSMUSG00000042686(gene)|ensembl:ENSMUST00000038382(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0014701"(junctional sarcoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|interpro:IPR003409(MORN motif)|interpro:IPR017191(Junctophilin)	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:GvuK5g6PoVIHiUTujD5cfRsnMRA10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P02469	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-6662997|ensembl:ENSMUSP00000002979|ensembl:ENSMUSP00000132778|uniprotkb:E9PXZ9	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:lamb1_mouse(display_long)|uniprotkb:Lamb1(gene name)|psi-mi:Lamb1(display_short)|uniprotkb:Lamb-1(gene name synonym)|uniprotkb:Lamb1-1(gene name synonym)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:XP_006515055.2|ensembl:ENSMUSG00000002900(gene)|ensembl:ENSMUST00000002979(transcript)|ensembl:ENSMUST00000169088(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0007611"(learning or memory)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042476"(odontogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8874081|go:"GO:0070831"(basement membrane assembly)|reactome:R-MMU-8957275|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P02469|rcsb pdb:4AQS|rcsb pdb:5MC9|refseq:XP_006515056.1	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:cUuVqY2JMeRrS9sDYudPy7hSIL010090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P54285	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-770995|uniprotkb:G5E821|ensembl:ENSMUSP00000155514	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:cacb3_mouse(display_long)|uniprotkb:Calcium channel voltage-dependent subunit beta 3(gene name synonym)|uniprotkb:Cacnb3(gene name)|psi-mi:Cacnb3(display_short)|uniprotkb:Cacnlb3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_031607.2|ensembl:ENSMUSG00000003352(gene)|ensembl:ENSMUST00000230490(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902630"(regulation of membrane hyperpolarization)|go:"GO:1905788"(negative regulation of detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008079(Voltage-dependent calcium channel, L-type, beta-3 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035760|interpro:IPR036028|reactome:R-MMU-112308|reactome:R-MMU-422356	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:LMu4stgWoR/M2O+zARtbshs2Ptc10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P61014	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-10148373|uniprotkb:P20006|uniprotkb:Q3UQ75|ensembl:ENSMUSP00000045709|ensembl:ENSMUSP00000132743|ensembl:ENSMUSP00000151641|ensembl:ENSMUSP00000151745|ensembl:ENSMUSP00000151860|ensembl:ENSMUSP00000151966	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:ppla_mouse(display_long)|uniprotkb:Pln(gene name)|psi-mi:Pln(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001135399.1|refseq:NP_075618.1|ensembl:ENSMUST00000046221(transcript)|ensembl:ENSMUST00000163319(transcript)|ensembl:ENSMUST00000218468(transcript)|ensembl:ENSMUST00000219491(transcript)|ensembl:ENSMUST00000219921(transcript)|ensembl:ENSMUST00000220197(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008016"(regulation of heart contraction)|ensembl:ENSMUSG00000038583(gene)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033574"(response to testosterone)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086023"(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:1901077"(regulation of relaxation of muscle)|go:"GO:1901877"(negative regulation of calcium ion binding)|go:"GO:1901895"(negative regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902081"(negative regulation of calcium ion import into sarcoplasmic reticulum)|interpro:IPR005984(Phospholamban)|rcsb pdb:3O7L|reactome:R-MMU-5578775|reactome:R-MMU-936837	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:/rJRfpGBnSyV37L7wJcTtmVsrRc10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P10126	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-773865|uniprotkb:Q61511|uniprotkb:Q6ZWN2|uniprotkb:Q8BMB8|uniprotkb:Q8BVS8|uniprotkb:Q99KU5|ensembl:ENSMUSP00000042457	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:ef1a1_mouse(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	dip:DIP-46609N|refseq:NP_034236.2|ensembl:ENSMUSG00000037742(gene)|ensembl:ENSMUST00000042235(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P10126|reactome:R-MMU-156842|reactome:R-MMU-3371511|reactome:R-MMU-6798695|reactome:R-MMU-8876725	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:85G9Uje743KzA02bB/rmKuq2HbU10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q8K3W2	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-20565174|uniprotkb:Q8BUL2|ensembl:ENSMUSP00000073502	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:lrc10_mouse(display_long)|uniprotkb:Heart-restricted leucine-rich repeat protein(gene name synonym)|uniprotkb:Lrrc10(gene name)|psi-mi:Lrrc10(display_short)|uniprotkb:Hrlrrp(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_666354.1|ensembl:ENSMUSG00000060187(gene)|ensembl:ENSMUST00000073834(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055013"(cardiac muscle cell development)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0005634"(nucleus)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:iVf+u0C/TmZEEVpfHx0e2merlXA10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:Q8CC27	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-9690121|uniprotkb:A2ASJ8|uniprotkb:Q8C5J5|uniprotkb:Q9CTQ6|ensembl:ENSMUSP00000110371	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:cacb2_mouse(display_long)|uniprotkb:Cacnb2(gene name)|psi-mi:Cacnb2(display_short)|uniprotkb:Cacnlb2(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_001296448.1|refseq:NP_075605.1|refseq:XP_006497383.1|ensembl:ENSMUSG00000057914(gene)|ensembl:ENSMUST00000114723(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0007601"(visual perception)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR005444(Voltage-dependent calcium channel, L-type, beta-2 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035605|interpro:IPR036028|reactome:R-MMU-112308|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:v56B+tEzuDuYnl4Fri/+kK+ccSo10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q01815	uniprotkb:P11404	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	intact:EBI-3504145|uniprotkb:Q91W23|ensembl:ENSMUSP00000070709	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:fabph_mouse(display_long)|uniprotkb:Fabp3(gene name)|psi-mi:Fabp3(display_short)|uniprotkb:Fabph1(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565155|imex:IM-26422-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	refseq:NP_034304.1|ensembl:ENSMUSG00000028773(gene)|ensembl:ENSMUST00000070532(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P11404|reactome:R-MMU-163560	-	-	-	figure legend:Table S5, Fig. S3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rogid:dQml5A1cAEZVjH9htxeLPe4NrvI10090	rigid:1GvNsNL8eUKJeDHuuMVJVgFrvpk	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BH64	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1994334|uniprotkb:Q8BL28|ensembl:ENSMUSP00000096397	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ehd2_mouse(display_long)|uniprotkb:Ehd2(gene name)|psi-mi:Ehd2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:XP_011248884.1|refseq:NP_694708.2|dip:DIP-46806N|ensembl:ENSMUSG00000074364(gene)|ensembl:ENSMUST00000098799(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006897"(endocytosis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045171"(intercellular bridge)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029945|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|rcsb pdb:2QPT|rcsb pdb:4CID|reactome:R-MMU-983231	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Y6gH2n3nnVFeqaZE0T6T2gGqtyw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P11499	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q6PB66	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1371262|uniprotkb:Q8K4V0|uniprotkb:Q9CRX4|ensembl:ENSMUSP00000107927	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:lpprc_mouse(display_long)|uniprotkb:Lrpprc(gene name)|psi-mi:Lrpprc(display_short)|uniprotkb:Lrp130(gene name synonym)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_082509.2|ensembl:ENSMUSG00000024120(gene)|ensembl:ENSMUST00000112308(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|reactome:R-MMU-611105|reactome:R-MMU-9707564|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:Q6PB66|reactome:R-MMU-5628897|go:"GO:0005634"(nucleus)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:wNo59nF0OqIHfnoUrxN10z7YIGM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8JZN5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8369678|intact:MINT-4086603|uniprotkb:Q8BK76|uniprotkb:Q8C0B5|uniprotkb:Q3ULL9|ensembl:ENSMUSP00000011492	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:acad9_mouse(display_long)|uniprotkb:Acad9(gene name)|psi-mi:Acad9(display_short)|uniprotkb:Acyl-CoA dehydrogenase family member 9(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_766266.3|dip:DIP-59192N|ensembl:ENSMUSG00000027710(gene)|ensembl:ENSMUST00000011492(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030425"(dendrite)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:Q8JZN5|reactome:R-MMU-6799198	-	-	comment:mint|function:"Has a dehydrogenase activity on palmitoyl-CoA (C16:0) and stearoyl-CoA (C18:0). It is three times more active on palmitoyl-CoA then on stearoyl-CoA. Has little activity on octanoyl-CoA (C8:0), butyryl-CoA (C4:0) or isovaleryl-CoA (5:0)"	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:j4KumzEMeLE5MRemyIYKdtFNj1010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8QZS1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8345532|intact:MINT-1859357|ensembl:ENSMUSP00000045606	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hibch_mouse(display_long)|uniprotkb:Hibch(gene name)|psi-mi:Hibch(display_short)|uniprotkb:3-hydroxyisobutyryl-coenzyme A hydrolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_666220.1|ensembl:ENSMUSG00000041426(gene)|ensembl:ENSMUST00000044478(transcript)|go:"GO:0003860"(3-hydroxyisobutyryl-CoA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006574"(valine catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|interpro:IPR029045|interpro:IPR032259|mint:Q8QZS1|reactome:R-MMU-70895	-	-	comment:mint|function:"Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA"	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:V+/ZD4EBuZhQECvuCWuUDEuhS7c10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q7TQ48	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8345670|intact:MINT-4112166|uniprotkb:A6H5Y7|uniprotkb:Q8BS43|ensembl:ENSMUSP00000087986	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:srca_mouse(display_long)|uniprotkb:Srl(gene name)|psi-mi:Srl(display_short)|uniprotkb:Sar(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001334091.1|refseq:NP_780556.2|ensembl:ENSMUSG00000022519(gene)|ensembl:ENSMUST00000090500(transcript)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005525"(GTP binding)|go:"GO:0006897"(endocytosis)|go:"GO:0014873"(response to muscle activity involved in regulation of muscle adaptation)|go:"GO:0016197"(endosomal transport)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR031692|mint:Q7TQ48	-	-	comment:mint|function:May be involved in the regulation of calcium transport	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:5BTvE0E6BVftxG0Wezh9UMHpquw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8VDJ3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8317711|intact:MINT-1858511|ensembl:ENSMUSP00000043047|ensembl:ENSMUSP00000127903	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:vigln_mouse(display_long)|uniprotkb:Hdlbp(gene name)|psi-mi:Hdlbp(display_short)|uniprotkb:High density lipoprotein-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001288293.1|refseq:NP_598569.1|refseq:XP_006529137.1|refseq:XP_006529138.1|refseq:XP_006529139.1|refseq:XP_006529140.1|ensembl:ENSMUSG00000034088(gene)|ensembl:ENSMUST00000042498(transcript)|ensembl:ENSMUST00000170883(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006869"(lipid transport)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0034364"(high-density lipoprotein particle)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q8VDJ3|reactome:R-MMU-8964011	-	-	function:Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:H8VW/Tp0f9b24nwslsUWF+CW/xE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9JJZ2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8319860|uniprotkb:Q9CV57|uniprotkb:D4P911|intact:MINT-4137042|ensembl:ENSMUSP00000032233	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tba8_mouse(display_long)|uniprotkb:Tuba8(gene name)|psi-mi:Tuba8(display_short)|uniprotkb:Alpha-tubulin 8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_059075.1|ensembl:ENSMUSG00000030137(gene)|ensembl:ENSMUST00000032233(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9JJZ2|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5617833|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	-	comment:mint|function:Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:kSKDdPgABEPswCY1QpWaiYQjtlw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O88844	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8317306|ensembl:ENSMUSP00000127307|ensembl:ENSMUSP00000095316|uniprotkb:Q3UAV7|intact:MINT-1859161	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:idhc_mouse(display_long)|uniprotkb:Idh1(gene name)|psi-mi:Idh1(display_short)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUST00000097709(transcript)|ensembl:ENSMUST00000169032(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004448"(isocitrate dehydrogenase activity)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008585"(female gonad development)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0060696"(regulation of phospholipid catabolic process)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:O88844|rcsb pdb:5YZH|rcsb pdb:5YZI|reactome:R-MMU-389542|reactome:R-MMU-6798695|reactome:R-MMU-9033241|ensembl:ENSMUSG00000025950(gene)|refseq:NP_001104790.1|refseq:NP_034627.3	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Toc7c5pd1IUEj7JsoBe3+e2h4T810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9QUR6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8344942|intact:MINT-1854903|uniprotkb:Q80YS1|ensembl:ENSMUSP00000097444	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ppce_mouse(display_long)|uniprotkb:Prep(gene name)|psi-mi:Prep(display_short)|uniprotkb:Pep(gene name synonym)|uniprotkb:Post-proline cleaving enzyme(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035286.1|ensembl:ENSMUSG00000019849(gene)|ensembl:ENSMUST00000099858(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0070012"(oligopeptidase activity)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002470(Peptidase S9A, prolyl oligopeptidase)|interpro:IPR002471(Peptidase S9, serine active site)|interpro:IPR023302|interpro:IPR029058|mint:Q9QUR6	-	-	comment:mint|function:Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:LrkDBZS1o6Br0r14vkmXkGf5D4o10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P61358	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8401481|intact:MINT-1863099|ensembl:ENSMUSP00000090305|ensembl:ENSMUSP00000102870	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl27_mouse(display_long)|uniprotkb:Rpl27(gene name)|psi-mi:Rpl27(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035419.1|refseq:XP_017170385.1|ensembl:ENSMUSG00000063316(gene)|ensembl:ENSMUST00000077856(transcript)|ensembl:ENSMUST00000107249(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61358|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O08739	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8419036|uniprotkb:O88692|intact:MINT-4115626|uniprotkb:Q8CFR4|ensembl:ENSMUSP00000005829|ensembl:ENSMUSP00000130495	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ampd3_mouse(display_long)|uniprotkb:Ampd3(gene name)|psi-mi:Ampd3(display_short)|uniprotkb:AMP deaminase H-type(gene name synonym)|uniprotkb:AMP deaminase isoform E(gene name synonym)|uniprotkb:Heart-type AMPD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001263230.1|refseq:NP_033797.2|refseq:XP_006507285.1|refseq:XP_006507282.1|ensembl:ENSMUSG00000005686(gene)|ensembl:ENSMUST00000005829(transcript)|ensembl:ENSMUST00000170374(transcript)|go:"GO:0003876"(AMP deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006188"(IMP biosynthetic process)|go:"GO:0006196"(AMP catabolic process)|go:"GO:0032264"(IMP salvage)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0046031"(ADP metabolic process)|go:"GO:0046032"(ADP catabolic process)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0097009"(energy homeostasis)|interpro:IPR001365(Adenosine/AMP deaminase)|interpro:IPR006329(AMP deaminase)|interpro:IPR006650(Adenosine/AMP deaminase active site)|interpro:IPR029771|interpro:IPR032466|mint:O08739|reactome:R-MMU-6798695|reactome:R-MMU-74217	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:4oCNKt08UPpybp4POUcQGhLds3g10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P20065	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-7946048|intact:MINT-6542333|ensembl:ENSMUSP00000107797|ensembl:ENSMUSP00000107798	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tyb4_mouse(display_long)|uniprotkb:Tmsb4x(gene name)|psi-mi:Tmsb4x(display_short)|uniprotkb:Ptmb4(gene name synonym)|uniprotkb:Tmsb4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_067253.1|refseq:XP_006528822.1|rcsb pdb:3M3N|reactome:R-MMU-114608|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|interpro:IPR001152(Thymosin beta-4)|interpro:IPR038386|mint:P20065|rcsb pdb:1T44|ensembl:ENSMUSG00000049775(gene)|ensembl:ENSMUST00000112175(transcript)|ensembl:ENSMUST00000112176(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)	-	-	function:Seraspenide inhibits the entry of hematopoeitic pluripotent stem cells into the S-phase|comment:mint|function:"Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization"	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:JLA9SKFXflHenc1hfrf5hkVq5L410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CZS1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8354156|uniprotkb:Q3UAH5|intact:MINT-1869729|ensembl:ENSMUSP00000041260	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:al1b1_mouse(display_long)|uniprotkb:Aldh1b1(gene name)|psi-mi:Aldh1b1(display_short)|uniprotkb:Aldhx(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 1 member B1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_082546.1|ensembl:ENSMUSG00000035561(gene)|ensembl:ENSMUST00000044384(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:Q9CZS1|reactome:R-MMU-71384	-	-	comment:mint|function:ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:uC5KyWB4CBhkxyeLKO5Yl832ftY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q922B2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8315918|ensembl:ENSMUSP00000027602|uniprotkb:Q3U987|intact:MINT-1856918	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sydc_mouse(display_long)|uniprotkb:Dars1(gene name)|psi-mi:Dars1(display_short)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:Dars(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000026356(gene)|ensembl:ENSMUST00000027602(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0045202"(synapse)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004523(Aspartyl-tRNA synthetase, class IIb, archea/euk type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q922B2|refseq:NP_803228.2	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:H7kUtRmDz/6VlO4kR9jYORfDUqI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P61750	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-7569554|uniprotkb:Q9CXX3|uniprotkb:Q3TGC2|intact:MINT-1866425|uniprotkb:P36403|ensembl:ENSMUSP00000022429	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:arf4_mouse(display_long)|uniprotkb:Arf4(gene name)|psi-mi:Arf4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031505.1|ensembl:ENSMUSG00000021877(gene)|ensembl:ENSMUST00000022429(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61750|reactome:R-MMU-5620916|reactome:R-MMU-6807878|reactome:R-MMU-6811434	-	-	function:GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:UQ8GuyD6go1ZCYpUU69uTevxoVo10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q91ZJ5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8321545|intact:MINT-1856424|uniprotkb:Q8R3D2|ensembl:ENSMUSP00000099939	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ugpa_mouse(display_long)|uniprotkb:Ugp2(gene name)|psi-mi:Ugp2(display_short)|uniprotkb:UDP-glucose pyrophosphorylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_647458.1|refseq:NP_001277563.1|ensembl:ENSMUSG00000001891(gene)|ensembl:ENSMUST00000102875(transcript)|go:"GO:0003983"("UTP:glucose-1-phosphate uridylyltransferase activity")|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006011"(UDP-glucose metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0019255"(glucose 1-phosphate metabolic process)|go:"GO:0032557"(pyrimidine ribonucleotide binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR016267(UTP--glucose-1-phosphate uridylyltransferase, subgroup)|interpro:IPR029044|mint:Q91ZJ5|reactome:R-MMU-173599|reactome:R-MMU-3322077	-	-	comment:mint|function:Plays a central role as a glucosyl donor in cellular metabolic pathways	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:3B0OH1SvXwuWjcW1VkBCEyn+JlY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQX8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8320743|uniprotkb:Q4VA25|intact:MINT-4133297|ensembl:ENSMUSP00000104957	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rt36_mouse(display_long)|uniprotkb:Kgd4(gene name synonym)|uniprotkb:Mrps36(gene name)|psi-mi:Mrps36(display_short)|uniprotkb:Alpha-ketoglutarate dehydrogenase component 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_079645.1|ensembl:ENSMUSG00000061474(gene)|ensembl:ENSMUST00000109333(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0009353"(mitochondrial oxoglutarate dehydrogenase complex)|interpro:IPR020373|mint:Q9CQX8|reactome:R-MMU-5389840|reactome:R-MMU-5419276	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:RzE4Ki6XkUzmRN1h0OH5/frDP4Y10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9JLZ3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8345249|uniprotkb:Q8QZS0|intact:MINT-1861987|uniprotkb:Q80YD7|uniprotkb:Q9CY78|uniprotkb:Q9D155	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:auhm_mouse(display_long)|uniprotkb:Itaconyl-CoA hydratase(gene name synonym)|uniprotkb:Auh(gene name)|psi-mi:Auh(display_short)|uniprotkb:AU-specific RNA-binding enoyl-CoA hydratase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_057918.2|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:Q9JLZ3|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0004490"(methylglutaconyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0050011"(itaconyl-CoA hydratase activity)|reactome:R-MMU-70895|interpro:IPR001753(Crotonase, core)	-	-	comment:mint|function:Catalyzes the conversion of 3-methylglutaconyl-CoA to 3-hydroxy-3-methylglutaryl-CoA. Has very low enoyl-CoA hydratase activity. Was originally identified as RNA-binding protein that binds in vitro to clustered 5'-AUUUA-3' motifs	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:jb9Xjp4DtGg5cI4jv2hmjaydamk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O55124	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8344336|intact:MINT-4105158	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:o55124_mouse(display_long)|uniprotkb:Myom2(gene name)|psi-mi:Myom2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032690.2|mint:O55124|interpro:IPR036116|interpro:IPR036179|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:flGHrJLFPy45TlRjGR1w+o9tEuY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P50544	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8345582|intact:MINT-1860557|uniprotkb:O35289|uniprotkb:O55133|ensembl:ENSMUSP00000099634	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:acadv_mouse(display_long)|uniprotkb:Acadvl(gene name)|psi-mi:Acadvl(display_short)|uniprotkb:Vlcad(gene name synonym)|uniprotkb:MVLCAD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_059062.1|ensembl:ENSMUSG00000018574(gene)|ensembl:ENSMUST00000102574(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0090181"(regulation of cholesterol metabolic process)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|mint:P50544|reactome:R-MMU-77305	-	-	comment:mint|function:Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:4AfQt7R5VKSc3Q4cAyT1Iaknyoc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P21981	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8345304|intact:MINT-1869474|uniprotkb:Q8C217|uniprotkb:Q3TLV2|uniprotkb:Q91VG9|uniprotkb:O88901|uniprotkb:Q9R1F7|intact:UNK-5405895|ensembl:ENSMUSP00000099411	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tgm2_mouse(display_long)|uniprotkb:Tgm2(gene name)|psi-mi:Tgm2(display_short)|uniprotkb:Tissue transglutaminase(gene name synonym)|uniprotkb:Transglutaminase-2(gene name synonym)|uniprotkb:Isopeptidase TGM2(gene name synonym)|uniprotkb:Protein-glutamine deamidase TGM2(gene name synonym)|uniprotkb:Protein-glutamine dopaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine histaminyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine noradrenalinyltransferase TGM2(gene name synonym)|uniprotkb:Protein-glutamine serotonyltransferase TGM2(gene name synonym)|uniprotkb:Transglutaminase II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033399.1|ensembl:ENSMUSG00000037820(gene)|ensembl:ENSMUST00000103122(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0008233"(peptidase activity)|go:"GO:0008483"(transaminase activity)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0018153"("isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine")|go:"GO:0018277"(protein deamination)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050568"(protein-glutamine glutaminase activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0060348"(bone development)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0120295"(histone serotonyltransferase activity)|go:"GO:0120297"(histone dopaminyltransferase activity)|go:"GO:0120298"(peptide noradrenalinyltransferase activity)|go:"GO:0120299"(peptide histaminyltransferase activity)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904015"(cellular response to serotonin)|go:"GO:2000425"(regulation of apoptotic cell clearance)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:P21981	-	-	function:Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ZCd0oNYAuTlMAUwA1zBz0EgegMI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9QYR9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8344918|intact:MINT-1855915|uniprotkb:Q3T9C9|ensembl:ENSMUSP00000021649	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:acot2_mouse(display_long)|uniprotkb:Acot2(gene name)|psi-mi:Acot2(display_short)|uniprotkb:Mte1(gene name synonym)|uniprotkb:Acyl coenzyme A thioester hydrolase(gene name synonym)|uniprotkb:Very-long-chain acyl-CoA thioesterase(gene name synonym)|uniprotkb:MTE-I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_598949.3|ensembl:ENSMUSG00000021226(gene)|ensembl:ENSMUST00000021649(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|interpro:IPR006862(Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase)|interpro:IPR014940(BAAT/Acyl-CoA thioester hydrolase C-terminal)|interpro:IPR016662(Acyl-CoA thioesterase, long chain)|interpro:IPR029058|interpro:IPR042490|mint:Q9QYR9|reactome:R-MMU-77289|reactome:R-MMU-9033241	-	-	function:"Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Most active on substrates with chain lengths ranging from C14-C20"|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:zAZVr3zI759Kz2z5krUKEAw/73c10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A2AMM0	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8350940|uniprotkb:Q9D728|intact:MINT-4127323|uniprotkb:Q5FW67|uniprotkb:Q9CV87|uniprotkb:B1PRL4|ensembl:ENSMUSP00000030033	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cavn4_mouse(display_long)|uniprotkb:Cavin4(gene name)|psi-mi:Cavin4(display_short)|uniprotkb:Murc(gene name synonym)|uniprotkb:Muscle-related coiled-coil protein(gene name synonym)|uniprotkb:Muscle-restricted coiled-coil protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_080785.2|ensembl:ENSMUSG00000028348(gene)|ensembl:ENSMUST00000030033(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007517"(muscle organ development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030018"(Z disc)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0042383"(sarcolemma)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0055003"(cardiac myofibril assembly)|interpro:IPR026752|interpro:IPR033299|mint:A2AMM0	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:nrFSYGjm17ds8mZhj9Hrq2VzsAI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P97443	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8347383|uniprotkb:Q6DFW7|uniprotkb:P97442|intact:MINT-4134971|uniprotkb:P97444|ensembl:ENSMUSP00000073911	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:smyd1_mouse(display_long)|uniprotkb:Smyd1(gene name)|psi-mi:Smyd1(display_short)|uniprotkb:Bop(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 1(gene name synonym)|uniprotkb:Zinc finger protein BOP(gene name synonym)|uniprotkb:CD8b-opposite(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033892.2|refseq:NP_001153599.1|ensembl:ENSMUSG00000055027(gene)|ensembl:ENSMUST00000074301(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044418|mint:P97443|rcsb pdb:3N71	-	-	comment:mint|function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:HGx//OWPuLM5JyvcN7klcToKoAU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8R1Q8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8314868|ensembl:ENSMUSP00000035366|intact:MINT-4118631	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dc1l1_mouse(display_long)|uniprotkb:Dync1li1(gene name)|psi-mi:Dync1li1(display_short)|uniprotkb:Dncli1(gene name synonym)|uniprotkb:Dnclic1(gene name synonym)|uniprotkb:Dynein light intermediate chain 1, cytosolic(gene name synonym)|uniprotkb:Dynein light chain A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000032435(gene)|ensembl:ENSMUST00000047404(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007049"(cell cycle)|go:"GO:0019003"(GDP binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0046605"(regulation of centrosome cycle)|go:"GO:0051301"(cell division)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|interpro:IPR027417|mint:Q8R1Q8|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-9646399|reactome:R-MMU-9648025|refseq:NP_666341.1	-	-	function:May play a role in binding dynein to membranous organelles or chromosomes. May associate with the heavy chains in the dynein head where they might regulate enzyme activity|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:aAQ4kBil3eYqmqS/J6QhMDA6a4410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8K0D5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8344966|uniprotkb:Q921D6|uniprotkb:Q924I0|intact:MINT-4094092|ensembl:ENSMUSP00000076503	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:efgm_mouse(display_long)|uniprotkb:Gfm1(gene name)|psi-mi:Gfm1(display_short)|uniprotkb:Efg(gene name synonym)|uniprotkb:Efg1(gene name synonym)|uniprotkb:Gfm(gene name synonym)|uniprotkb:Elongation factor G 1, mitochondrial(gene name synonym)|uniprotkb:Elongation factor G1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_613057.2|ensembl:ENSMUSG00000027774(gene)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004540(Translation elongation factor EFG/EF2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009022(Elongation factor G, III and V)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR035649|interpro:IPR041095|mint:Q8K0D5|reactome:R-MMU-5389840|ensembl:ENSMUST00000077271(transcript)	-	-	function:This protein promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:bLV9LkkkN4KqS+NcAPA2F6b8eBo10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q60936	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8347051|uniprotkb:Q8K0M1|uniprotkb:Q9D657|uniprotkb:Q9JHR3|uniprotkb:Q9DBR5|intact:MINT-1859515|ensembl:ENSMUSP00000027766|ensembl:ENSMUSP00000128290	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:coq8a_mouse(display_long)|uniprotkb:Coq8a(gene name)|psi-mi:Coq8a(display_short)|uniprotkb:Adck3(gene name synonym)|uniprotkb:Cabc1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_075830.2|refseq:NP_001156762.1|refseq:XP_006497024.1|refseq:XP_006497025.1|ensembl:ENSMUSG00000026489(gene)|ensembl:ENSMUST00000027766(transcript)|ensembl:ENSMUST00000170472(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|mint:Q60936	-	-	function:May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:mBL+f8T49kJm+ryI9VCRcUFyLZM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P47934	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8346602|uniprotkb:Q923A6|uniprotkb:Q3TCG3|intact:MINT-4089666|uniprotkb:Q3V1Y3|ensembl:ENSMUSP00000028207|ensembl:ENSMUSP00000099919	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cacp_mouse(display_long)|uniprotkb:Crat(gene name)|psi-mi:Crat(display_short)|uniprotkb:Carnitine acetyltransferase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031786.2|ensembl:ENSMUSG00000026853(gene)|ensembl:ENSMUST00000028207(transcript)|ensembl:ENSMUST00000102855(transcript)|go:"GO:0003997"(acyl-CoA oxidase activity)|go:"GO:0004092"(carnitine O-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008458"(carnitine O-octanoyltransferase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0033540"(fatty acid beta-oxidation using acyl-CoA oxidase)|go:"GO:0046459"(short-chain fatty acid metabolic process)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042231|mint:P47934|rcsb pdb:1NDB|rcsb pdb:1NDF|rcsb pdb:1NDI|rcsb pdb:1T7N|rcsb pdb:1T7O|rcsb pdb:1T7Q|rcsb pdb:2H3P|rcsb pdb:2H3U|rcsb pdb:2H3W|reactome:R-MMU-389887|reactome:R-MMU-9033241	-	-	function:Carnitine acetylase is specific for short chain fatty acids. Carnitine acetylase seems to affect the flux through the pyruvate dehydrogenase complex. It may be involved as well in the transport of acetyl-CoA into mitochondria|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:0M/qKmIjnQiSzBdagoRdKY3SE8A10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P31428	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8366678|intact:MINT-4101665|uniprotkb:G5E824|ensembl:ENSMUSP00000019422	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dpep1_mouse(display_long)|uniprotkb:Dpep1(gene name)|psi-mi:Dpep1(display_short)|uniprotkb:Mbd1(gene name synonym)|uniprotkb:Rdp(gene name synonym)|uniprotkb:Microsomal dipeptidase(gene name synonym)|uniprotkb:Renal dipeptidase(gene name synonym)|uniprotkb:Membrane-bound dipeptidase 1(gene name synonym)|uniprotkb:Beta-lactamase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:XP_017168047.1|refseq:NP_031902.2|ensembl:ENSMUSG00000019278(gene)|ensembl:ENSMUST00000019422(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0006751"(glutathione catabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008800"(beta-lactamase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0016999"(antibiotic metabolic process)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034235"(GPI anchor binding)|go:"GO:0035690"|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070573"(metallodipeptidase activity)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0072341"(modified amino acid binding)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028536|interpro:IPR032466|mint:P31428|reactome:R-MMU-2142691|reactome:R-MMU-5423646	-	-	comment:mint|function:Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:KlnWfCtMTpa+4caks6z1sBzoNEA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D1R9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-7977843|intact:MINT-1857602|uniprotkb:Q497V4|ensembl:ENSMUSP00000078092|ensembl:ENSMUSP00000086614|ensembl:ENSMUSP00000142486	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl34_mouse(display_long)|uniprotkb:Rpl34(gene name)|psi-mi:Rpl34(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001186279.1|refseq:NP_001005859.1|refseq:XP_001481222.1|refseq:NP_081000.1|refseq:NP_001274510.1|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000062006(gene)|ensembl:ENSMUST00000062601(transcript)|ensembl:ENSMUST00000079085(transcript)|ensembl:ENSMUST00000196202(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR008195(Ribosomal protein L34e)|interpro:IPR018065|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:i4RSoK1rXY2RQeVjL+6iNKoD49U10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9QVP4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8357276|uniprotkb:Q9JIE8|intact:MINT-4102168|uniprotkb:Q63977|ensembl:ENSMUSP00000099985	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mlra_mouse(display_long)|uniprotkb:Myl7(gene name)|psi-mi:Myl7(display_short)|uniprotkb:Mylc2a(gene name synonym)|uniprotkb:Myosin regulatory light chain 7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_075017.2|ensembl:ENSMUSG00000020469(gene)|ensembl:ENSMUST00000102921(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0031672"(A band)|go:"GO:0043197"(dendritic spine)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9QVP4|reactome:R-MMU-445355	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:leuWAVQCkKG0daoyT4BpClk7lyc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q99LC5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8334254|uniprotkb:Q8BMD3|intact:MINT-1859759|uniprotkb:Q4V9X5|uniprotkb:Q3THD7|uniprotkb:Q8BMU7|uniprotkb:Q3V000|ensembl:ENSMUSP00000034866	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:etfa_mouse(display_long)|uniprotkb:Etfa(gene name)|psi-mi:Etfa(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_663590.3|ensembl:ENSMUSG00000032314(gene)|ensembl:ENSMUST00000034866(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017133"(mitochondrial electron transfer flavoprotein complex)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947|mint:Q99LC5|reactome:R-MMU-611105	-	-	comment:mint|function:"The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)"	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:J1V6KKCCnRXkfr72ArCLeyh9FLg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q61425	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8334772|uniprotkb:Q925U9|uniprotkb:Q3UFI0|uniprotkb:Q8K149|uniprotkb:Q3THK8|intact:MINT-1859897|uniprotkb:Q3TF75|ensembl:ENSMUSP00000029610	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hcdh_mouse(display_long)|uniprotkb:Mschad(gene name synonym)|uniprotkb:Schad(gene name synonym)|uniprotkb:Hadh(gene name)|psi-mi:Hadh(display_short)|uniprotkb:Hadhsc(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032238.2|ensembl:ENSMUSG00000027984(gene)|ensembl:ENSMUST00000029610(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q61425|reactome:R-MMU-77310|reactome:R-MMU-77346|reactome:R-MMU-77348|reactome:R-MMU-77350|reactome:R-MMU-77352	-	-	function:Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:5WS+ia58ttrPB/tirUQTBt3I0xw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D881	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8333990|intact:MINT-4127563|ensembl:ENSMUSP00000038961|ensembl:ENSMUSP00000141554	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q9d881_mouse(display_long)|uniprotkb:Cox5b-ps(gene name)|psi-mi:Cox5b-ps(display_short)|uniprotkb:Cox5b(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit 5B, mitochondrial(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034072.2|ensembl:ENSMUSG00000061518(gene)|ensembl:ENSMUSG00000079941(gene)|ensembl:ENSMUST00000044043(transcript)|ensembl:ENSMUST00000193210(transcript)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|mint:Q9D881	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:uNmBv2pPOF9/GjoM6yIkTGwnHmw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8K010	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8317731|uniprotkb:Q8R3K2|intact:MINT-1855298|ensembl:ENSMUSP00000023222|ensembl:ENSMUSP00000129100	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:opla_mouse(display_long)|uniprotkb:Oplah(gene name)|psi-mi:Oplah(display_short)|uniprotkb:5-oxo-L-prolinase(gene name synonym)|uniprotkb:Pyroglutamase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_694762.1|refseq:XP_006521572.1|ensembl:ENSMUSG00000022562(gene)|ensembl:ENSMUST00000023222(transcript)|ensembl:ENSMUST00000171340(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0017168"("5-oxoprolinase (ATP-hydrolyzing) activity")|go:"GO:0042802"(identical protein binding)|interpro:IPR002821(Hydantoinase/oxoprolinase)|interpro:IPR003692(Hydantoinase B/oxoprolinase)|interpro:IPR008040(Hydantoinaseoxoprolinase, N-terminal)|mint:Q8K010|reactome:R-MMU-174403	-	-	function:Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:gkKIeYhA8/HRMdl4BR6ggW+oC1Y10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q5SW19	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8315491|intact:UNK-5482502|intact:MINT-4115908|uniprotkb:Q3U4M5|uniprotkb:Q3V3Q8|intact:UNK-5408909|uniprotkb:Q505Q6|uniprotkb:Q6PAT1|uniprotkb:Q8CHD9|uniprotkb:Q6GQX1|uniprotkb:Q3U014|intact:UNK-5473899|intact:UNK-5429492|uniprotkb:A8Y5E2	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:clu_mouse(display_long)|uniprotkb:Cluh(gene name)|psi-mi:Cluh(display_short)|uniprotkb:Kiaa0664(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR033646|interpro:IPR025697|refseq:NP_001074627.1|interpro:IPR027523|interpro:IPR028275|refseq:XP_006534416.1|refseq:XP_006534417.1|mint:Q5SW19|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023231	-	-	comment:"fragmentation type: fragment"|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:hyZPFP7G2ri2LuDUtQ2FgZwOggA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9WVK4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8321414|intact:MINT-1863155|ensembl:ENSMUSP00000025684	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ehd1_mouse(display_long)|uniprotkb:Ehd1(gene name)|psi-mi:Ehd1(display_short)|uniprotkb:Past1(gene name synonym)|uniprotkb:PAST homolog 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034249.1|dip:DIP-59491N|ensembl:ENSMUSG00000024772(gene)|ensembl:ENSMUST00000025684(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9WVK4|reactome:R-MMU-983231	-	-	comment:mint|function:Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:6eI3lDw0K5kWK6+oxA8kBTDydHs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P04919	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8350852|intact:MINT-1861446|ensembl:ENSMUSP00000006749	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:b3at_mouse(display_long)|uniprotkb:Slc4a1(gene name)|psi-mi:Slc4a1(display_short)|uniprotkb:Ae1(gene name synonym)|uniprotkb:Anion exchange protein 1(gene name synonym)|uniprotkb:Solute carrier family 4 member 1(gene name synonym)|uniprotkb:MEB3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035533.1|ensembl:ENSMUSG00000006574(gene)|ensembl:ENSMUST00000006749(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0007596"(blood coagulation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010037"(response to carbon dioxide)|go:"GO:0014704"(intercalated disc)|go:"GO:0014823"(response to activity)|go:"GO:0015106"(bicarbonate transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015301"("anion:anion antiporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0019899"(enzyme binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030018"(Z disc)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0035811"(negative regulation of urine volume)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045852"(pH elevation)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1904539"(negative regulation of glycolytic process through fructose-6-phosphate)|interpro:IPR001717(Anion exchange protein)|interpro:IPR002977(Anion exchange protein 1)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|interpro:IPR018241|mint:P04919|reactome:R-MMU-1237044|reactome:R-MMU-1247673|reactome:R-MMU-425381	-	-	comment:mint|function:"Band 3 is the major integral glycoprotein of the erythrocyte membrane. Band 3 has two functional domains. Its integral domain mediates a 1:1 exchange of inorganic anions across the membrane, whereas its cytoplasmic domain provides binding sites for cytoskeletal proteins, glycolytic enzymes, and hemoglobin"	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Qq0Xf0faIrE7Mqa++JNT5ryYNYc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P04247	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8312622|ensembl:ENSMUSP00000019037|ensembl:ENSMUSP00000125995|ensembl:ENSMUSP00000128399|ensembl:ENSMUSP00000155115|intact:MINT-4102659	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:myg_mouse(display_long)|uniprotkb:Mb(gene name)|psi-mi:Mb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000018893(gene)|ensembl:ENSMUST00000019037(transcript)|ensembl:ENSMUST00000166179(transcript)|ensembl:ENSMUST00000169226(transcript)|ensembl:ENSMUST00000229423(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0009725"(response to hormone)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031444"(slow-twitch skeletal muscle fiber contraction)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050873"(brown fat cell differentiation)|interpro:IPR000971(Globin, subset)|interpro:IPR002335(Myoglobin)|interpro:IPR009050(Globin-like)|mint:P04247|reactome:R-MMU-8981607|go:"GO:0007507"(heart development)|refseq:NP_001157520.1|refseq:NP_038621.2|refseq:NP_001157519.1	-	-	function:Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:t8d0m/glCqCdeTFXQ1rvC8QtukU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P17563	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8362477|uniprotkb:Q91X87|intact:MINT-1854683|ensembl:ENSMUSP00000088349	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sbp1_mouse(display_long)|uniprotkb:Selenbp1(gene name)|psi-mi:Selenbp1(display_short)|uniprotkb:Lpsb(gene name synonym)|uniprotkb:56 kDa selenium-binding protein(gene name synonym)|uniprotkb:Selenium-binding protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033176.2|ensembl:ENSMUSG00000068874(gene)|ensembl:ENSMUST00000090839(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008430"(selenium binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0018549"(methanethiol oxidase activity)|go:"GO:0050873"(brown fat cell differentiation)|interpro:IPR008826(Selenium-binding protein)|mint:P17563	-	-	comment:mint|function:Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:/sDrAhh3tD4jaVfdnMSfJSeGAqQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BGK2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8347214|uniprotkb:Q8C4L0|intact:MINT-4110342|ensembl:ENSMUSP00000033825	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:arhl1_mouse(display_long)|uniprotkb:Adprhl1(gene name)|psi-mi:Adprhl1(display_short)|uniprotkb:Arh2(gene name synonym)|uniprotkb:ADP-ribosylhydrolase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_766338.1|ensembl:ENSMUSG00000031448(gene)|ensembl:ENSMUST00000033825(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003875"(ADP-ribosylarginine hydrolase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0051725"(protein de-ADP-ribosylation)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR005502(ADP-ribosylation/Crystallin J1)|interpro:IPR012108(ADP-ribosylarginine hydrolase)|interpro:IPR036705|mint:Q8BGK2	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:dNndFUfWcvqF021hxTxdHsO0gXQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q99NB1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8346875|intact:MINT-4086737|uniprotkb:Q8K0M6|ensembl:ENSMUSP00000028944	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:acs2l_mouse(display_long)|uniprotkb:Acss1(gene name)|psi-mi:Acss1(display_short)|uniprotkb:Acas2(gene name synonym)|uniprotkb:Acas2l(gene name synonym)|uniprotkb:Acetate--CoA ligase 2(gene name synonym)|uniprotkb:Acetyl-CoA synthetase 2(gene name synonym)|uniprotkb:Acyl-CoA synthetase short-chain family member 1(gene name synonym)|uniprotkb:Propionate--CoA ligase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_542142.1|dip:DIP-61209N|ensembl:ENSMUSG00000027452(gene)|ensembl:ENSMUST00000028944(transcript)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0019413"(acetate biosynthetic process)|go:"GO:0019427"(acetyl-CoA biosynthetic process from acetate)|go:"GO:0019542"(propionate biosynthetic process)|go:"GO:0050218"(propionate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011904(Acetate--CoA ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR032387|interpro:IPR042099|mint:Q99NB1|reactome:R-MMU-71384	-	-	function:"Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2)"|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:h3dcddwI6x6n1h9/eQAdHaNuIMA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3UIZ8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8346945|intact:MINT-4112993|uniprotkb:Q3V3V0|uniprotkb:Q8BWD1|uniprotkb:B0LY41|ensembl:ENSMUSP00000034133	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mylk3_mouse(display_long)|uniprotkb:Mylk3(gene name)|psi-mi:Mylk3(display_short)|uniprotkb:Cardiac-MyBP-C-associated Ca/CaM kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001284541.1|refseq:NP_780650.2|ensembl:ENSMUSG00000031698(gene)|ensembl:ENSMUST00000034133(transcript)|go:"GO:0002528"(regulation of vascular permeability involved in acute inflammatory response)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0004687"(myosin light chain kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060298"(positive regulation of sarcomere organization)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q3UIZ8	-	-	comment:mint|function:May play a role in smooth muscle contraction	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:E6v7rwzuXaDhiSZjX1U+lwIwRC810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O35206	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8350088|intact:MINT-4104642|uniprotkb:Q9EQD9|uniprotkb:Q3UZ71|uniprotkb:A2AJY3|ensembl:ENSMUSP00000099981	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cofa1_mouse(display_long)|uniprotkb:Col15a1(gene name)|psi-mi:Col15a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034058.2|ensembl:ENSMUSG00000028339(gene)|ensembl:ENSMUST00000102917(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001886"(endothelial cell morphogenesis)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005581"(collagen trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR010515(Collagenase NC10 and endostatin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|mint:O35206|rcsb pdb:1DY2|reactome:R-MMU-1442490|reactome:R-MMU-1650814|reactome:R-MMU-2022090|reactome:R-MMU-8948216	-	-	comment:mint|function:Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle|function:Endostatin potently inhibits angiogenesis	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:BEh6LTG+OjUMMxw/h8cKIOrcFWw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P62717	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8327568|uniprotkb:P11249|intact:MINT-1841289|uniprotkb:Q3TSN0|ensembl:ENSMUSP00000058368	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl18a_mouse(display_long)|uniprotkb:Rpl18a(gene name)|psi-mi:Rpl18a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_084027.1|ensembl:ENSMUSG00000045128(gene)|ensembl:ENSMUST00000054220(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR021138|interpro:IPR023573|interpro:IPR028877|mint:P62717|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:HMbe4GVCuVZs0/90BMnEgpOqeiA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9QYG0	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8319326|uniprotkb:Q3TI48|uniprotkb:Q3TY42|uniprotkb:Q3U3T5|uniprotkb:Q69ZN2|uniprotkb:Q8C661|intact:MINT-1854707|ensembl:ENSMUSP00000004673	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndrg2_mouse(display_long)|uniprotkb:Ndrg2(gene name)|psi-mi:Ndrg2(display_short)|uniprotkb:Ndr2(gene name synonym)|uniprotkb:Kiaa1248(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 2 protein(gene name synonym)|uniprotkb:Protein Ndr2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:XP_006519161.2|refseq:XP_006519162.2|refseq:NP_038892.1|refseq:NP_001139431.1|refseq:XP_006519166.1|refseq:XP_006519167.1|refseq:XP_006519168.1|refseq:XP_017171534.1|refseq:XP_017171535.1|refseq:XP_017171536.1|refseq:XP_017171538.1|refseq:XP_017171539.1|refseq:XP_017171540.1|ensembl:ENSMUSG00000004558(gene)|ensembl:ENSMUST00000004673(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010574"(regulation of vascular endothelial growth factor production)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090361"(regulation of platelet-derived growth factor production)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030690|mint:Q9QYG0|rcsb pdb:2QMQ	-	-	function:May be involved in dendritic cell and neuron differentiation|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:gjnqnwthmc6Q2ZeVGRMbifbjy6k10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P35980	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-7977881|uniprotkb:Q9D987|intact:MINT-1857698|uniprotkb:Q9CQF1|ensembl:ENSMUSP00000072320|ensembl:ENSMUSP00000147816	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl18_mouse(display_long)|uniprotkb:Rpl18(gene name)|psi-mi:Rpl18(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033103.2|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR000039(Ribosomal protein L18e)|interpro:IPR021131|interpro:IPR021132|interpro:IPR036227|mint:P35980|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|ensembl:ENSMUSG00000059070(gene)|ensembl:ENSMUST00000072503(transcript)|ensembl:ENSMUST00000210640(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|reactome:R-MMU-975957	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:PqTr3iXlemHDle24HNyRs+yPRJg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3UTJ2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8345744|uniprotkb:Q80TS1|intact:MINT-1853612|uniprotkb:Q3USC6|uniprotkb:Q8BX47|uniprotkb:Q8CHU0|uniprotkb:Q8BLW9|intact:MINT-4116161|uniprotkb:Q8BJL6|uniprotkb:Q8BJU3	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:srbs2_mouse(display_long)|uniprotkb:Sorbs2(gene name)|psi-mi:Sorbs2(display_short)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Argbp2(gene name synonym)|uniprotkb:Kiaa0777(gene name synonym)|uniprotkb:Arg-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001297636.1|interpro:IPR003127(Sorbin-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028506|interpro:IPR036028|mint:Q3UTJ2|refseq:XP_006509449.1|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR001452(Src homology-3)	-	-	comment:"fragmentation type: fragment"	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:2sKDQux/2IV7mW8l6LK36D3qlqw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P34914	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8321134|intact:MINT-1859181|uniprotkb:Q8CGV0|ensembl:ENSMUSP00000069209	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hyes_mouse(display_long)|uniprotkb:Ephx2(gene name)|psi-mi:Ephx2(display_short)|uniprotkb:Eph2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001258332.1|refseq:NP_031966.2|ensembl:ENSMUSG00000022040(gene)|ensembl:ENSMUST00000070515(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002539"(prostaglandin production involved in inflammatory response)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0033885"("10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity")|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0046272"(stilbene catabolic process)|go:"GO:0046839"(phospholipid dephosphorylation)|go:"GO:0052642"(lysophosphatidic acid phosphatase activity)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0097176"(epoxide metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR023214|interpro:IPR029058|interpro:IPR036412|interpro:IPR041492|mint:P34914|rcsb pdb:1CQZ|rcsb pdb:1CR6|rcsb pdb:1EK1|rcsb pdb:1EK2|reactome:R-MMU-2142670|reactome:R-MMU-9018682|reactome:R-MMU-9033241	-	-	function:"Acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. Has phosphatase activity"|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:jK9/K11NHaeX7vX0aK77T/hbYlU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q62234	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8344887|intact:UNK-5482362|uniprotkb:Q6PAC0|intact:MINT-4102904|uniprotkb:Q546T8|ensembl:ENSMUSP00000072945	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:myom1_mouse(display_long)|uniprotkb:Myom1(gene name)|psi-mi:Myom1(display_short)|uniprotkb:Myomesin family member 1(gene name synonym)|uniprotkb:Skelemin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034997.2|refseq:NP_001077403.1|ensembl:ENSMUSG00000024049(gene)|ensembl:ENSMUST00000073211(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:Q62234|rcsb pdb:2JTD|rcsb pdb:4V10	-	-	comment:mint|function:May link the intermediate filament cytoskeleton to the M-disc of the myofibrils in striated muscle. May also contact myosin filaments. Also binds beta-integrins	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:sfJeAhoFhpjW9v1ci8pVYx2k30410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P19783	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-7174084|ensembl:ENSMUSP00000034276|ensembl:ENSMUSP00000138019|uniprotkb:Q545A9|intact:MINT-1860013	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cox41_mouse(display_long)|uniprotkb:Cox4i1(gene name)|psi-mi:Cox4i1(display_short)|uniprotkb:Cox4(gene name synonym)|uniprotkb:Cox4a(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001280488.1|refseq:NP_034071.2|ensembl:ENSMUSG00000031818(gene)|ensembl:ENSMUST00000034276(transcript)|ensembl:ENSMUST00000181586(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P19783|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564	-	-	function:This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:zt2qwV/jVAo1B9UISW8R2votzlU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P45952	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8344397|uniprotkb:Q64235|intact:MINT-1860219|ensembl:ENSMUSP00000072483	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:acadm_mouse(display_long)|uniprotkb:Acadm(gene name)|psi-mi:Acadm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031408.1|ensembl:ENSMUSG00000062908(gene)|ensembl:ENSMUST00000072697(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001889"(liver development)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007507"(heart development)|go:"GO:0009409"(response to cold)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016853"(isomerase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0030424"(axon)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|mint:P45952|reactome:R-MMU-77288|reactome:R-MMU-77346|reactome:R-MMU-77348	-	-	function:This enzyme is specific for acyl chain lengths of 4 to 16|comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Zfgo1s6CGy4mfJ3L1T7CHc6vQd810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8VBT1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8345141|intact:MINT-4136992|uniprotkb:Q3UVB8|uniprotkb:B2RU93|uniprotkb:Q8BUK2|ensembl:ENSMUSP00000044936	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:txlnb_mouse(display_long)|uniprotkb:Txlnb(gene name)|psi-mi:Txlnb(display_short)|uniprotkb:Mdp77(gene name synonym)|uniprotkb:Muscle-derived protein 77(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_619534.2|ensembl:ENSMUSG00000039891(gene)|ensembl:ENSMUST00000037964(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0019905"(syntaxin binding)|interpro:IPR026183|mint:Q8VBT1	-	-	comment:mint|function:Promotes motor nerve regeneration. May be involved in intracellular vesicle traffic	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:XJFhpi3mkSVyJwYZROmHwnvsof010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P51174	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8345212|uniprotkb:O35302|uniprotkb:Q9CU29|uniprotkb:Q9DB83|uniprotkb:B2KGC6|intact:MINT-1861818|uniprotkb:Q8QZR6	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:acadl_mouse(display_long)|uniprotkb:Acadl(gene name)|psi-mi:Acadl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|refseq:NP_031407.2|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR034179|interpro:IPR036250|interpro:IPR037069|mint:P51174|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0016401"(palmitoyl-CoA oxidase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042413"(carnitine catabolic process)|go:"GO:0042758"(long-chain fatty acid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|reactome:R-MMU-77285|reactome:R-MMU-77310|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:AhEJczI8Mvr0mAx2w1u+QFZ+fWA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O88492	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8347295|uniprotkb:Q69Z80|uniprotkb:E9QN72|intact:MINT-4105562|uniprotkb:Q8BNV5|ensembl:ENSMUSP00000002908|ensembl:ENSMUSP00000139859	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:plin4_mouse(display_long)|uniprotkb:Kiaa1881(gene name synonym)|uniprotkb:Adipocyte protein S3-12(gene name synonym)|uniprotkb:Plin4(gene name)|psi-mi:Plin4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_065593.2|ensembl:ENSMUSG00000002831(gene)|ensembl:ENSMUST00000002908(transcript)|ensembl:ENSMUST00000190703(transcript)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR004279(Perilipin)|mint:O88492	-	-	comment:mint|function:May play a role in triacylglycerol packaging into adipocytes. May function as a coat protein involved in the biogenesis of lipid droplets	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:VIrsWg+3qqLWYOcp+l6NNgXcG2M10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q04857	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8345547|intact:MINT-4091372|ensembl:ENSMUSP00000001147	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:co6a1_mouse(display_long)|uniprotkb:Col6a1(gene name)|psi-mi:Col6a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034063.1|ensembl:ENSMUSG00000001119(gene)|ensembl:ENSMUST00000001147(transcript)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042383"(sarcolemma)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036465|mint:Q04857|reactome:R-MMU-1442490|reactome:R-MMU-1650814|reactome:R-MMU-186797|reactome:R-MMU-2022090|reactome:R-MMU-216083|reactome:R-MMU-3000178|reactome:R-MMU-419037|reactome:R-MMU-8948216	-	-	comment:mint|function:Collagen VI acts as a cell-binding protein	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:kM8Xi8xfLOEcDb2NpFlknxpak8U10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q02788	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8344999|uniprotkb:Q05505|uniprotkb:Q8K229|uniprotkb:Q8C972|intact:MINT-4381294|ensembl:ENSMUSP00000001181	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:co6a2_mouse(display_long)|uniprotkb:Col6a2(gene name)|psi-mi:Col6a2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001334136.1|refseq:NP_666119.1|ensembl:ENSMUSG00000020241(gene)|ensembl:ENSMUST00000001181(transcript)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0009749"(response to glucose)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036465|mint:Q02788|reactome:R-MMU-1442490|reactome:R-MMU-1650814|reactome:R-MMU-186797|reactome:R-MMU-2022090|reactome:R-MMU-216083|reactome:R-MMU-3000178|reactome:R-MMU-419037|reactome:R-MMU-8948216	-	-	comment:mint|function:Collagen VI acts as a cell-binding protein	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Hos3zhgwneI4J8IyHoLA8msT8PA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O08528	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8344432|intact:MINT-262872|ensembl:ENSMUSP00000000642	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hxk2_mouse(display_long)|uniprotkb:Hk2(gene name)|psi-mi:Hk2(display_short)|uniprotkb:Hexokinase type II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_038848.1|dip:DIP-41484N|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:O08528|reactome:R-MMU-70171|ensembl:ENSMUSG00000000628(gene)|ensembl:ENSMUST00000000642(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007595"(lactation)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0008865"(fructokinase activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019158"(mannokinase activity)|go:"GO:0035795"(negative regulation of mitochondrial membrane permeability)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046324"(regulation of glucose import)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001312(Hexokinase)	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Gm80aqf9jxkgIUOQFjicRMUq2wE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q02013	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8357389|uniprotkb:Q91VY8|uniprotkb:Q542P1|intact:MINT-4088080|ensembl:ENSMUSP00000004774	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:aqp1_mouse(display_long)|uniprotkb:Aqp1(gene name)|psi-mi:Aqp1(display_short)|uniprotkb:Aquaporin-CHIP(gene name synonym)|uniprotkb:Delayed early response protein 2(gene name synonym)|uniprotkb:Water channel protein for red blood cells and kidney proximal tubule(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031498.1|ensembl:ENSMUSG00000004655(gene)|ensembl:ENSMUST00000004774(transcript)|go:"GO:0003094"(glomerular filtration)|go:"GO:0003097"(renal water transport)|go:"GO:0005223"(intracellular cGMP-activated cation channel activity)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005372"(water transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005903"(brush border)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006833"(water transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009992"(cellular water homeostasis)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015168"(glycerol transmembrane transporter activity)|go:"GO:0015250"(water channel activity)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0015696"|go:"GO:0015793"(glycerol transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0020003"(symbiont-containing vacuole)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030104"(water homeostasis)|go:"GO:0030184"(nitric oxide transmembrane transporter activity)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031526"(brush border membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032127"(dense core granule membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0032940"(secretion by cell)|go:"GO:0033363"(secretory granule organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035377"(transepithelial water transport)|go:"GO:0035378"(carbon dioxide transmembrane transport)|go:"GO:0035379"(carbon dioxide transmembrane transporter activity)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0042538"(hyperosmotic salinity response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0043679"(axon terminus)|go:"GO:0044241"(lipid digestion)|go:"GO:0045177"(apical part of cell)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046878"(positive regulation of saliva secretion)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051458"(corticotropin secretion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070295"(renal water absorption)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071472"(cellular response to salt stress)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0072220"(metanephric descending thin limb development)|go:"GO:0072230"(metanephric proximal straight tubule development)|go:"GO:0072232"(metanephric proximal convoluted tubule segment 2 development)|go:"GO:0072239"(metanephric glomerulus vasculature development)|go:"GO:0085018"(obsolete maintenance of symbiont-containing vacuole by host)|interpro:IPR000425(Major intrinsic protein)|interpro:IPR022357|interpro:IPR023271|interpro:IPR023274|interpro:IPR034294|mint:Q02013|reactome:R-MMU-1237044|reactome:R-MMU-1247673|reactome:R-MMU-432040|reactome:R-MMU-432047	-	-	comment:mint|function:Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:gEjUoy5vU5wxLye+36pxx8WOI8010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P02468	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-7059830|intact:MINT-1031545	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:lamc1_mouse(display_long)|uniprotkb:Lamc1(gene name)|psi-mi:Lamc1(display_short)|uniprotkb:Lamb-2(gene name synonym)|uniprotkb:Lamc-1(gene name synonym)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	mint:P02468|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|rcsb pdb:1KLO|rcsb pdb:1NPE|rcsb pdb:1TLE|rcsb pdb:4AQT|rcsb pdb:5MC9|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8874081|dip:DIP-41793N	-	-	comment:mint|function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:LTc4oIJUjQ8INjkodiPpXvL/rx010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D172	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8321099|intact:MINT-1841972|ensembl:ENSMUSP00000001242	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:gal3a_mouse(display_long)|uniprotkb:Gatd3(gene name)|psi-mi:Gatd3(display_short)|uniprotkb:D10Jhu81e(gene name synonym)|uniprotkb:Gatd3a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_613067.1|ensembl:ENSMUSG00000053329(gene)|ensembl:ENSMUST00000001242(transcript)|go:"GO:0005739"(mitochondrion)|interpro:IPR029062|mint:Q9D172	-	-	comment:mint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:yaWG8Dudv7cOIDqG+5bFSWgJ5+810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P54116	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8004826|intact:UNK-5380204|uniprotkb:O88988|uniprotkb:Q62455|uniprotkb:Q60744|uniprotkb:Q3UP81|ensembl:ENSMUSP00000028241	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:stom_mouse(display_long)|uniprotkb:Stom(gene name)|psi-mi:Stom(display_short)|uniprotkb:Epb7.2(gene name synonym)|uniprotkb:Epb72(gene name synonym)|uniprotkb:Protein 7.2b(gene name synonym)|uniprotkb:Erythrocyte band 7 integral membrane protein(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 7.2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_038543.1|ensembl:ENSMUSG00000026880(gene)|ensembl:ENSMUST00000028241(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901585"(regulation of acid-sensing ion channel activity)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR018080|interpro:IPR028515|interpro:IPR036013|interpro:IPR043202|rcsb pdb:4FVF|rcsb pdb:4FVG|rcsb pdb:4FVJ|reactome:R-MMU-2672351|reactome:R-MMU-6798695|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013406|reactome:R-MMU-9013407	-	-	comment:mint|function:Thought to regulate cation conductance. May regulate ACCN1 and ACCN3 gating|comment:homomint	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:UBRFUbNiNCadUYpzdYLI+e4QhFA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P08032	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8350116|uniprotkb:B2RWX6|intact:MINT-85326|uniprotkb:P97502|ensembl:ENSMUSP00000027817	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:spta1_mouse(display_long)|uniprotkb:Spta1(gene name)|psi-mi:Spta1(display_short)|uniprotkb:Spna1(gene name synonym)|uniprotkb:Spta(gene name synonym)|uniprotkb:Erythroid alpha-spectrin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035595.2|ensembl:ENSMUSG00000026532(gene)|ensembl:ENSMUST00000027817(transcript)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036028|mint:P08032|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878	-	-	comment:mint|function:Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:uaswmTQnd1d+MrnYyCICUC3vTkM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O70468	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	-	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9WVC3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8391580|uniprotkb:Q3TYR4|intact:MINT-4089976|ensembl:ENSMUSP00000000058	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cav2_mouse(display_long)|uniprotkb:Cav2(gene name)|psi-mi:Cav2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_058596.1|ensembl:ENSMUSG00000000058(gene)|ensembl:ENSMUST00000000058(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0070836"(caveola assembly)|go:"GO:0071711"(basement membrane organization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR033306|mint:Q9WVC3|reactome:R-MMU-9009391	-	-	comment:mint|function:May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-2 may function as an accessory protein in conjunction with caveolin-1	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:7uHkkNB0YWB8GqAcSn/J7S9Q67o10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P15508	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-8312472|intact:MINT-1867611	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sptb1_mouse(display_long)|uniprotkb:Sptb(gene name)|psi-mi:Sptb(display_short)|uniprotkb:Spnb1(gene name synonym)|uniprotkb:Spnb-1(gene name synonym)|uniprotkb:Sptb1(gene name synonym)|uniprotkb:Beta-I spectrin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|go:"GO:0032991"(protein-containing complex)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|interpro:IPR018159|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR036872|mint:P15508|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)	-	-	comment:mint|function:Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:z4EphKJwcEvoChbzc2oiLhL+nCw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q6URW6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-776061|uniprotkb:Q80V64|uniprotkb:Q80ZE6|uniprotkb:B3F3T1|ensembl:ENSMUSP00000046059	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:myh14_mouse(display_long)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym)|uniprotkb:Myh14(gene name)|psi-mi:Myh14(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_082297.1|refseq:XP_011249204.1|refseq:XP_011249205.1|refseq:NP_001258467.1|refseq:NP_001258469.1|refseq:XP_017167802.1|ensembl:ENSMUSG00000030739(gene)|ensembl:ENSMUST00000048102(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005903"(brush border)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0043209"(myelin sheath)|go:"GO:0051015"(actin filament binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097513"(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|reactome:R-MMU-5627123	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:2ykxEou72Agq7pSGmgrW1gezPS810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q00623	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1634106|uniprotkb:Q8BPD5|uniprotkb:O08855|uniprotkb:O09042|ensembl:ENSMUSP00000034588	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:apoa1_mouse(display_long)|uniprotkb:Apoa1(gene name)|psi-mi:Apoa1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033822.2|ensembl:ENSMUSG00000032083(gene)|ensembl:ENSMUST00000034588(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:Q00623|rcsb pdb:2LEM|reactome:R-MMU-114608|reactome:R-MMU-1369062|reactome:R-MMU-2168880|reactome:R-MMU-3000471|reactome:R-MMU-3000480|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8963888|reactome:R-MMU-8963896|reactome:R-MMU-8963901|reactome:R-MMU-8964011|reactome:R-MMU-8964058|reactome:R-MMU-9707616|reactome:R-MMU-975634	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:RFvdsVcof99jM6K/bEi1N1Vn9hE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q99MR9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-777504|uniprotkb:Q32MS0|uniprotkb:Q8BUJ4|uniprotkb:Q8BUL0|ensembl:ENSMUSP00000049054	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ppr3a_mouse(display_long)|uniprotkb:Protein phosphatase 1 glycogen-associated regulatory subunit(gene name synonym)|uniprotkb:Protein phosphatase type-1 glycogen targeting subunit(gene name synonym)|uniprotkb:Ppp1r3a(gene name)|psi-mi:Ppp1r3a(display_short)|uniprotkb:Pp1g(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_536712.2|ensembl:ENSMUSG00000042717(gene)|ensembl:ENSMUST00000045096(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:2001069"(glycogen binding)|interpro:IPR005036(Putative phosphatase regulatory subunit)|interpro:IPR038175|mint:Q99MR9	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:89I6gnZquuUFCWRqj6qNp2zwh3A10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P53395	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773148|uniprotkb:Q3TMF5|ensembl:ENSMUSP00000000349	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:odb2_mouse(display_long)|uniprotkb:"Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase"(gene name synonym)|uniprotkb:Dihydrolipoamide branched chain transacylase(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex(gene name synonym)|uniprotkb:Dbt(gene name)|psi-mi:Dbt(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034152.2|ensembl:ENSMUSG00000000340(gene)|ensembl:ENSMUST00000000349(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0031405"(lipoic acid binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043754"("dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity")|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P53395|reactome:R-MMU-389661|reactome:R-MMU-70895|reactome:R-MMU-9013407	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:/g3DD7tq0CE5mqTJD4ZifLuIy5E10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:E9Q401	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P05201	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-494448|intact:EBI-2308970|uniprotkb:Q3UJH8|ensembl:ENSMUSP00000026196	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:aatc_mouse(display_long)|uniprotkb:Transaminase A(gene name synonym)|uniprotkb:Glutamate oxaloacetate transaminase 1(gene name synonym)|uniprotkb:Cysteine aminotransferase, cytoplasmic(gene name synonym)|uniprotkb:Cysteine transaminase, cytoplasmic(gene name synonym)|uniprotkb:Got1(gene name)|psi-mi:Got1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034454.2|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0004609"(phosphatidylserine decarboxylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006114"(glycerol biosynthetic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0019550"(glutamate catabolic process to aspartate)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|go:"GO:0030170"(pyridoxal phosphate binding)|ensembl:ENSMUSG00000025190(gene)|ensembl:ENSMUST00000026196(transcript)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0043679"(axon terminus)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0047801"(L-cysteine transaminase activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060290"(transdifferentiation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:1990267"(response to transition metal nanoparticle)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P05201|reactome:R-MMU-70263|reactome:R-MMU-8963693	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:4if14ijxqySSUHcJ2S2EXDyBzZQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q11011	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2309833|uniprotkb:Q3UZE0|uniprotkb:Q91VJ8|uniprotkb:Q5PR74|ensembl:ENSMUSP00000001480	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:psa_mouse(display_long)|uniprotkb:Npepps(gene name)|psi-mi:Npepps(display_short)|uniprotkb:Psa(gene name synonym)|uniprotkb:Cytosol alanyl aminopeptidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032968.2|ensembl:ENSMUSG00000001441(gene)|ensembl:ENSMUST00000001480(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|mint:Q11011|reactome:R-MMU-983168	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:3bY21UZD4p6P4+IIJstPb9R27LE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9WTR5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-9072186|uniprotkb:Q8BG11|ensembl:ENSMUSP00000113527	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cad13_mouse(display_long)|uniprotkb:Cdh13(gene name)|psi-mi:Cdh13(display_short)|uniprotkb:Heart cadherin(gene name synonym)|uniprotkb:Truncated cadherin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_062681.2|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0050927"(positive regulation of positive chemotaxis)|go:"GO:0051668"(localization within membrane)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0055100"(adiponectin binding)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR002126(Cadherin)|ensembl:ENSMUSG00000031841(gene)|ensembl:ENSMUST00000117160(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016342"(catenin complex)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR033216|interpro:IPR039808|rcsb pdb:3K5R|rcsb pdb:3K6F|reactome:R-MMU-418990	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:NO1Sah9tJOFZIh43y82zLv5u/qg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9Z1W8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-11568972|uniprotkb:Q8VHY2|uniprotkb:Q32MR8|ensembl:ENSMUSP00000007340	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:at12a_mouse(display_long)|uniprotkb:Atp1al1(gene name synonym)|uniprotkb:"Non-gastric H(+)/K(+) ATPase subunit alpha"(gene name synonym)|uniprotkb:Proton pump(gene name synonym)|uniprotkb:Atp12a(gene name)|psi-mi:Atp12a(display_short)|uniprotkb:HK alpha 2(gene name synonym)|uniprotkb:"Non-gastric Na(+)/K(+) ATPase subunit alpha"(gene name synonym)|uniprotkb:Sodium pump(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_619593.2|ensembl:ENSMUSG00000022229(gene)|ensembl:ENSMUST00000007340(transcript)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006885"(regulation of pH)|go:"GO:0008900"("P-type potassium:proton transporter activity")|go:"GO:0010038"(response to metal ion)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030318|interpro:IPR036412|interpro:IPR044492|reactome:R-MMU-936837	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:UhIAcoKBKEPYftd/IFfswIMseVE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P11531	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P26039	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1039593|uniprotkb:Q8VEF0|uniprotkb:A2AIM8|ensembl:ENSMUSP00000030187	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tln1_mouse(display_long)|uniprotkb:Tln1(gene name)|psi-mi:Tln1(display_short)|uniprotkb:Tln(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035732.2|refseq:XP_006537832.2|ensembl:ENSMUSG00000028465(gene)|ensembl:ENSMUST00000030187(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:P26039|rcsb pdb:1SJ7|rcsb pdb:1SJ8|rcsb pdb:1T01|rcsb pdb:1U89|rcsb pdb:1XWX|rcsb pdb:1Y19|rcsb pdb:1ZW3|rcsb pdb:2B0H|rcsb pdb:2G35|rcsb pdb:2JSW|rcsb pdb:2KBB|rcsb pdb:2KC1|rcsb pdb:2KC2|rcsb pdb:2KGX|rcsb pdb:2KMA|rcsb pdb:2KVP|rcsb pdb:2L10|rcsb pdb:2L7A|rcsb pdb:2L7N|rcsb pdb:2LQG|rcsb pdb:2QDQ|rcsb pdb:2X0C|rcsb pdb:3DYJ|rcsb pdb:3IVF|rcsb pdb:3S90|rcsb pdb:4F7G|rcsb pdb:4W8P|rcsb pdb:5FZT|rcsb pdb:5IC0|rcsb pdb:5IC1|rcsb pdb:5NL1|rcsb pdb:6BA6|rcsb pdb:6MFS|rcsb pdb:6TWN|rcsb pdb:6VGU|reactome:R-MMU-114608|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-399955|reactome:R-MMU-445355|reactome:R-MMU-5674135|dip:DIP-647N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:w9NQrwqUcuVAzeesymnTmhrEtCk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BTM8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-641991|uniprotkb:B7FAV0|uniprotkb:O54934|uniprotkb:Q7TQI1|uniprotkb:Q8BLK1|uniprotkb:Q8BTN7|uniprotkb:Q8VHX5|uniprotkb:Q8VHX8|uniprotkb:Q99KQ2|ensembl:ENSMUSP00000033699	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:flna_mouse(display_long)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:Flna(gene name)|psi-mi:Flna(display_short)|uniprotkb:Fln(gene name synonym)|uniprotkb:Fln1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:XP_006527974.1|ensembl:ENSMUST00000033699(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|ensembl:ENSMUSG00000031328(gene)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0097368"(establishment of Sertoli cell barrier)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q8BTM8|reactome:R-MMU-114608|reactome:R-MMU-430116|reactome:R-MMU-446353|reactome:R-MMU-5627123	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:hp3whHs7nFMTtChpQ/KywkPalq810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P63017	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-433443|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q3U6R0|uniprotkb:Q3U764|uniprotkb:Q3U7D7|uniprotkb:Q3U7E2|uniprotkb:Q3U9B4|uniprotkb:Q3U9G0|uniprotkb:Q3UGM0|uniprotkb:Q5FWJ6|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375|uniprotkb:Q6NZD0|ensembl:ENSMUSP00000015800	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hsp7c_mouse(display_long)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Hsc73(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_112442.2|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0031906"(late endosome lumen)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0030425"(dendrite)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0005681"(spliceosomal complex)|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-450408|reactome:R-MMU-6798695|reactome:R-MMU-72163|reactome:R-MMU-8856828|reactome:R-MMU-8876725|reactome:R-MMU-888590|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P63017|rcsb pdb:3CQX|reactome:R-MMU-3371453|reactome:R-MMU-3371497|ensembl:ENSMUSG00000015656(gene)|ensembl:ENSMUST00000015800(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|dip:DIP-32353N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D0M3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773129|uniprotkb:Q3TDC5|uniprotkb:Q3UAN2|uniprotkb:Q63ZW4|uniprotkb:Q9DCG0|ensembl:ENSMUSP00000023210	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cy1_mouse(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 4(gene name synonym)|uniprotkb:Complex III subunit 4(gene name synonym)|uniprotkb:Complex III subunit IV(gene name synonym)|uniprotkb:Cyc1(gene name)|psi-mi:Cyc1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_079843.1|ensembl:ENSMUSG00000022551(gene)|ensembl:ENSMUST00000023210(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0020037"(heme binding)|go:"GO:0033762"(response to glucagon)|go:"GO:0046872"(metal ion binding)|interpro:IPR002326(Cytochrome c1)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR021157|interpro:IPR036909|mint:Q9D0M3|reactome:R-MMU-611105	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:tcTgdCV0NKIvzZsYmq8cBV4D5QY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9Z0X1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773597|intact:EBI-4282542|uniprotkb:Q1L6K5|ensembl:ENSMUSP00000041104	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:aifm1_mouse(display_long)|uniprotkb:Programmed cell death protein 8(gene name synonym)|uniprotkb:Aifm1(gene name)|psi-mi:Aifm1(display_short)|uniprotkb:Aif(gene name synonym)|uniprotkb:Pdcd8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001277293.1|refseq:NP_036149.1|ensembl:ENSMUSG00000036932(gene)|ensembl:ENSMUST00000037349(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0004174"(electron-transferring-flavoprotein dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:Q9Z0X1|rcsb pdb:1GV4|rcsb pdb:3GD3|rcsb pdb:3GD4|rcsb pdb:5MIU|rcsb pdb:5MIV	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:c0oYNXW1lpmieqgWc4TZra/RJNk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q61595	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-775369|uniprotkb:Q8BG49|uniprotkb:Q8BHF4|uniprotkb:Q8BHM8|uniprotkb:Q8C9Y5|uniprotkb:Q8CG51|uniprotkb:Q8CG52|uniprotkb:Q8CG53|uniprotkb:Q8CG54|uniprotkb:Q8CG55|uniprotkb:Q8CG56|uniprotkb:Q8CG57|uniprotkb:Q8CG58|uniprotkb:Q8CG59|uniprotkb:Q8CG60|uniprotkb:Q8CG61|uniprotkb:Q8CG62|uniprotkb:Q8CG63	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ktn1_mouse(display_long)|uniprotkb:Ktn1(gene name)|psi-mi:Ktn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032503.2|refseq:NP_001280564.1|refseq:NP_001280565.1|interpro:IPR024854|refseq:NP_001334448.1|refseq:NP_001334449.1|refseq:NP_001334450.1|refseq:NP_001334452.1|refseq:NP_001334453.1|refseq:NP_001334454.1|refseq:NP_001334455.1|refseq:NP_001334456.1|refseq:NP_001334457.1|mint:Q61595|interpro:IPR007794(Ribosome receptor lysine or proline rich)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|reactome:R-MMU-381426|reactome:R-MMU-5625970|reactome:R-MMU-8957275|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013408|reactome:R-MMU-9696264|reactome:R-MMU-9696270	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:xgS8/yfp5yj+gPyaC6a/gmSrxTA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P50396	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1634930|uniprotkb:A2AMA8|uniprotkb:Q3TBI9|uniprotkb:Q8VHM3|uniprotkb:Q91Y71|uniprotkb:Q91Z41|uniprotkb:Q96CX5|ensembl:ENSMUSP00000015435	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:gdia_mouse(display_long)|uniprotkb:Gdi1(gene name)|psi-mi:Gdi1(display_short)|uniprotkb:Rabgdia(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000015291(gene)|ensembl:ENSMUST00000015435(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030424"(axon)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|refseq:NP_034403.1|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0051592"(response to calcium ion)|go:"GO:0090315"(negative regulation of protein targeting to membrane)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50396|reactome:R-MMU-8876198|go:"GO:0043209"(myelin sheath)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:PedrlfCE1ZCgXPtL9PZmNfOoxdo10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q71LX8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2657945	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q71lx8_mouse(display_long)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84b(gene name synonym)|uniprotkb:Hspcb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032328.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P35441	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6171593	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tsp1_mouse(display_long)|uniprotkb:Thbs1(gene name)|psi-mi:Thbs1(display_short)|uniprotkb:Tsp1(gene name synonym)|uniprotkb:Glycoprotein G(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002581"(negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0002605"(negative regulation of dendritic cell antigen processing and presentation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0043236"(laminin binding)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070052"(collagen V binding)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030141"(secretory granule)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|reactome:R-MMU-114608|reactome:R-MMU-186797|reactome:R-MMU-216083|reactome:R-MMU-5173214|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016477"(cell migration)|interpro:IPR001881(EGF-like calcium-binding)|mint:P35441|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR017897|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR028499|interpro:IPR028974|interpro:IPR036383	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:0j9TPpvxNW9TNMFkFCNo+9wD3fA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P41216	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-4321047|uniprotkb:Q6GTG6|uniprotkb:Q9DBK5|ensembl:ENSMUSP00000034046|ensembl:ENSMUSP00000106001	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:acsl1_mouse(display_long)|uniprotkb:Acsl1(gene name)|psi-mi:Acsl1(display_short)|uniprotkb:Acsl2(gene name synonym)|uniprotkb:Facl2(gene name synonym)|uniprotkb:Long-chain acyl-CoA synthetase 1(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Phytanate--CoA ligase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032007.2|refseq:XP_006509325.2|refseq:NP_001289092.1|refseq:XP_006509327.1|refseq:XP_006509328.1|refseq:XP_006509329.1|refseq:XP_017168052.1|ensembl:ENSMUSG00000018796(gene)|ensembl:ENSMUST00000034046(transcript)|ensembl:ENSMUST00000110372(transcript)|go:"GO:0000038"(very long-chain fatty acid metabolic process)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010747"(positive regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0034201"(response to oleic acid)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042493"|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0050197"(phytanate-CoA ligase activity)|go:"GO:0070251"(pristanate-CoA ligase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR025110|mint:P41216|reactome:R-MMU-2046105|reactome:R-MMU-2046106|reactome:R-MMU-75876|go:"GO:0005778"(peroxisomal membrane)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:cu8xz7WxYLAAakkxjDxBy/2iso010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q925I1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-772703|uniprotkb:Q3UE74|uniprotkb:Q69ZM7|uniprotkb:Q8C6C6|uniprotkb:A2AD89|uniprotkb:Q3TA78|ensembl:ENSMUSP00000030903	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:atad3_mouse(display_long)|uniprotkb:AAA-ATPase TOB3(gene name synonym)|uniprotkb:Atad3(gene name)|psi-mi:Atad3(display_short)|uniprotkb:Atad3a(gene name synonym)|uniprotkb:Kiaa1273(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_849534.2|dip:DIP-32373N|ensembl:ENSMUSG00000029036(gene)|ensembl:ENSMUST00000030903(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q925I1|reactome:R-MMU-6798695	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ftt3s2Khsm5F0iodev1GLQFMHqg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P68368	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2642970|uniprotkb:Q3TY31|uniprotkb:P05215|ensembl:ENSMUSP00000140657	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tba4a_mouse(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033473.1|ensembl:ENSMUSG00000026202(gene)|ensembl:ENSMUST00000186213(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68368|reactome:R-MMU-114608|reactome:R-MMU-190840|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-2132295	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P46638	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1634944|ensembl:ENSMUSP00000110021	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rb11b_mouse(display_long)|uniprotkb:Rab11b(gene name)|psi-mi:Rab11b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033023.1|ensembl:ENSMUSG00000077450(gene)|ensembl:ENSMUST00000057373(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0006887"(exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0019003"(GDP binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0033572"(transferrin transport)|go:"GO:0035773"(insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0045054"(constitutive secretory pathway)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P46638|reactome:R-MMU-8854214|reactome:R-MMU-8873719	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:McbcmcV5cB7IE3GFkiDNIB5WcsM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q71H74	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20566038	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q71h74_mouse(display_long)|uniprotkb:Dpysl3(gene name)|psi-mi:Dpysl3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR006680(Amidohydrolase 1)|interpro:IPR030628|interpro:IPR011059(Metal-dependent hydrolase, composite)|go:"GO:0005737"(cytoplasm)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0048678"(response to axon injury)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:MOYaTG0ULTrtd1LKU3pxRRTD8/g10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8VEM8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-775967|uniprotkb:Q542V7|ensembl:ENSMUSP00000075987|ensembl:ENSMUSP00000132480	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mpcp_mouse(display_long)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)|uniprotkb:Slc25a3(gene name)|psi-mi:Slc25a3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_598429.1|dip:DIP-32038N|ensembl:ENSMUSG00000061904(gene)|ensembl:ENSMUST00000076694(transcript)|ensembl:ENSMUST00000164505(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0015293"(symporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q8VEM8	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:6fSO1eOaHLRSJSNq/PWlTfVpsUA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q62261	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-397843|ensembl:ENSMUSP00000006629|ensembl:ENSMUSP00000011877|uniprotkb:A2AFU1|uniprotkb:Q3TEM7|uniprotkb:Q5SQL8|uniprotkb:Q5SQL9|uniprotkb:Q9QWJ7	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sptb2_mouse(display_long)|uniprotkb:Sptbn1(gene name)|psi-mi:Sptbn1(display_short)|uniprotkb:Spnb-2(gene name synonym)|uniprotkb:Spnb2(gene name synonym)|uniprotkb:Sptb2(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym)|uniprotkb:Embryonic liver fodrin(gene name synonym)|uniprotkb:Elf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000020315(gene)|ensembl:ENSMUST00000006629(transcript)|ensembl:ENSMUST00000011877(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q62261|rcsb pdb:1BTN|rcsb pdb:1MPH|rcsb pdb:6M3P|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424|refseq:NP_033286.2|refseq:NP_787030.2|refseq:XP_006514662.1|refseq:XP_006514663.1|dip:DIP-31558N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:N6xVFU+ocY6PXsIz5ZIsA05bGPs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q61768	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-776129|uniprotkb:Q5BL10|uniprotkb:O08711|uniprotkb:Q61580|ensembl:ENSMUSP00000025083	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:kinh_mouse(display_long)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Khcs(gene name synonym)|uniprotkb:Kns1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032474.2|dip:DIP-32053N|ensembl:ENSMUSG00000006740(gene)|ensembl:ENSMUST00000025083(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q61768|rcsb pdb:6IGN|rcsb pdb:6IGV|reactome:R-MMU-2132295|reactome:R-MMU-5625970|reactome:R-MMU-6811434|reactome:R-MMU-983189	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:11aePhwWZOqqAabjyanVgdHQQso10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQ69	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1219646|ensembl:ENSMUSP00000053145|ensembl:ENSMUSP00000104649	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:qcr8_mouse(display_long)|uniprotkb:Uqcrq(gene name)|psi-mi:Uqcrq(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 9.5 kDa protein(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Complex III subunit 8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_079628.1|refseq:NP_001313543.1|ensembl:ENSMUSG00000044894(gene)|ensembl:ENSMUST00000061326(transcript)|ensembl:ENSMUST00000109021(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0021539"(subthalamus development)|go:"GO:0021548"(pons development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030901"(midbrain development)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR004205(UcrQ)|interpro:IPR036642|mint:Q9CQ69|reactome:R-MMU-611105	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:D31g2yr7auK53pPni0uZ10drZrY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9DCW4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1634288|uniprotkb:Q810V3|ensembl:ENSMUSP00000004729	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:etfb_mouse(display_long)|uniprotkb:Etfb(gene name)|psi-mi:Etfb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_080971.2|ensembl:ENSMUSG00000004610(gene)|ensembl:ENSMUST00000004729(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0017133"(mitochondrial electron transfer flavoprotein complex)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|interpro:IPR000049(Electron transfer flavoprotein, beta-subunit, core)|interpro:IPR012255(Electron transfer flavoprotein, beta subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR033948|mint:Q9DCW4|reactome:R-MMU-611105|reactome:R-MMU-8876725	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:eCcG+jkuQlxw/TzcOkzCBoAKJ8Y10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D2G2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773210|uniprotkb:Q3UEA0|uniprotkb:Q4FK55|uniprotkb:Q8CIE8|ensembl:ENSMUSP00000060346|ensembl:ENSMUSP00000152664	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:odo2_mouse(display_long)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:Dlst(gene name)|psi-mi:Dlst(display_short)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_084501.1|ensembl:ENSMUSG00000004789(gene)|ensembl:ENSMUST00000053811(transcript)|ensembl:ENSMUST00000221357(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:Q9D2G2|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:jyBoApRkfA3STOc5qJ01/cE2UHU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O08553	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P14094	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-770851|ensembl:ENSMUSP00000027863	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3USK2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20566025|ensembl:ENSMUSP00000158953	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3usk2_mouse(display_long)|uniprotkb:Csnk1d(gene name)|psi-mi:Csnk1d(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:XP_011246964.1|refseq:XP_011246965.1|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|ensembl:ENSMUSG00000025162(gene)|ensembl:ENSMUST00000239115(transcript)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:MZ20aRsK94+rC06ASWj6FolMlXo10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3TSA5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20564594	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3tsa5_mouse(display_long)|uniprotkb:Pabpc4(gene name)|psi-mi:Pabpc4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR036053|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WFmYVUqfxdBLyC5d6vIUVI4vjbg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9QYJ0	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-772431|ensembl:ENSMUSP00000034138	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dnja2_mouse(display_long)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short)|uniprotkb:mDj3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_062768.1|ensembl:ENSMUSG00000031701(gene)|ensembl:ENSMUST00000034138(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:Q9QYJ0|reactome:R-MMU-3371497	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ZYn3t1WpFrPa82gsMHxjaQRPr3k10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P54071	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773401|uniprotkb:Q8C2R9|uniprotkb:Q9EQK1|ensembl:ENSMUSP00000103007	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:idhp_mouse(display_long)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:Idh2(gene name)|psi-mi:Idh2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_766599.2|ensembl:ENSMUSG00000030541(gene)|ensembl:ENSMUST00000107384(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004448"(isocitrate dehydrogenase activity)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P54071|rcsb pdb:5H3E|rcsb pdb:5H3F|reactome:R-MMU-2151201|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:CkBZHIePaNGTtcgyqEf03oczVM010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P63038	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BU30	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6909077|ensembl:ENSMUSP00000048096|ensembl:ENSMUSP00000126806|ensembl:ENSMUSP00000132082|uniprotkb:Q6NXK4	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:syic_mouse(display_long)|uniprotkb:Iars(gene name synonym)|uniprotkb:Isoleucyl-tRNA synthetase(gene name synonym)|uniprotkb:Iars1(gene name)|psi-mi:Iars1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:XP_006516889.1|ensembl:ENSMUSG00000037851(gene)|ensembl:ENSMUST00000047363(transcript)|ensembl:ENSMUST00000164260(transcript)|ensembl:ENSMUST00000165316(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004822"(isoleucine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006428"(isoleucyl-tRNA aminoacylation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0051020"(GTPase binding)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002301(Isoleucyl-tRNA synthetase, class Ia)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR023586|interpro:IPR033709|mint:Q8BU30|refseq:NP_742012.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:xOIl+VyRSco1eDBN0Cs35nQSk3I10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9Z2I9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773730|uniprotkb:Q3TVH1|uniprotkb:Q8BGS6|ensembl:ENSMUSP00000022706|ensembl:ENSMUSP00000123765	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sucb1_mouse(display_long)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym)|uniprotkb:Sucla2(gene name)|psi-mi:Sucla2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035636.1|ensembl:ENSMUSG00000022110(gene)|ensembl:ENSMUST00000022706(transcript)|ensembl:ENSMUST00000160507(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004774"(succinate-CoA ligase activity)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0043209"(myelin sheath)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9Z2I9|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:e0MauyqzSv/9q7Pt5r5PzQ+yI6c10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O88342	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6914976|ensembl:ENSMUSP00000005234	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:wdr1_mouse(display_long)|uniprotkb:Wdr1(gene name)|psi-mi:Wdr1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:1990266"(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|reactome:R-MMU-114608|ensembl:ENSMUSG00000005103(gene)|ensembl:ENSMUST00000005234(transcript)|go:"GO:0002102"(podosome)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0040011"(locomotion)|go:"GO:0042247"(establishment of planar polarity of follicular epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043297"(apical junction assembly)|refseq:NP_035845.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:PVIlQDv8eXQrI3QBWJOjKlj/Zig10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O08529	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-643151|uniprotkb:O35518|uniprotkb:O54843|ensembl:ENSMUSP00000068895	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:can2_mouse(display_long)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)|uniprotkb:80 kDa M-calpain subunit(gene name synonym)|uniprotkb:Capn2(gene name)|psi-mi:Capn2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033924.2|interpro:IPR002048(Calcium-binding EF-hand)|ensembl:ENSMUSG00000026509(gene)|ensembl:ENSMUST00000068505(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007565"(female pregnancy)|go:"GO:0000785"(chromatin)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001824"(blastocyst development)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031143"(pseudopodium)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0005509"(calcium ion binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029539|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:O08529|reactome:R-MMU-1474228	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:1AC+IJ8bHwaYB7bBlMFxmV8PNss10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O55143	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-770763|uniprotkb:Q9R2A9|uniprotkb:Q9WUT5|ensembl:ENSMUSP00000031423|ensembl:ENSMUSP00000135935	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:at2a2_mouse(display_long)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)|uniprotkb:Atp2a2(gene name)|psi-mi:Atp2a2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001103610.1|refseq:NP_033852.1|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0006996"(organelle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:O55143|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000029467(gene)|ensembl:ENSMUST00000031423(transcript)|ensembl:ENSMUST00000179939(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:LJG8hpHG2pO9ePikEKYbhsuCeRI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A1IGX6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565311	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a1igx6_mouse(display_long)|uniprotkb:dsg4(gene name)|psi-mi:dsg4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	-	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:5OytYwmMK4XjALbm3t2qvwfkyvw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9DCX2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2255503|uniprotkb:B1ASE1|uniprotkb:Q542H1|uniprotkb:Q7M0I0|uniprotkb:Q91YK9|ensembl:ENSMUSP00000046256|ensembl:ENSMUSP00000086072|ensembl:ENSMUSP00000102147|ensembl:ENSMUSP00000137071	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:atp5h_mouse(display_long)|uniprotkb:Atp5pd(gene name)|psi-mi:Atp5pd(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:Atp5h(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_082138.1|refseq:XP_006534317.1|ensembl:ENSMUSG00000034566(gene)|ensembl:ENSMUST00000043931(transcript)|ensembl:ENSMUST00000073791(transcript)|ensembl:ENSMUST00000106537(transcript)|ensembl:ENSMUST00000180072(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1901653"(cellular response to peptide)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:Q9DCX2|reactome:R-MMU-163210|reactome:R-MMU-8949613	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:OJ9KqZtJ9IxSLv0aHm0DcOI9d7w10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q7TMM9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2255578|ensembl:ENSMUSP00000060246	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tbb2a_mouse(display_long)|uniprotkb:Tubb2(gene name synonym)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033476.1|ensembl:ENSMUSG00000058672(gene)|ensembl:ENSMUST00000056427(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q7TMM9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8CGY6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20564709|uniprotkb:Q5XG72|uniprotkb:Q8BHC5|uniprotkb:Q8BWK3|ensembl:ENSMUSP00000103795|ensembl:ENSMUSP00000129405	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:un45b_mouse(display_long)|uniprotkb:Unc45b(gene name)|psi-mi:Unc45b(display_short)|uniprotkb:Cmya4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_848795.3|ensembl:ENSMUSG00000018845(gene)|ensembl:ENSMUST00000108160(transcript)|ensembl:ENSMUST00000164945(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0030154"(cell differentiation)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019734|interpro:IPR024660	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Xetcx0PhEqUjY8JYtoKmEouOCJk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q6ZWN5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-12600852|ensembl:ENSMUSP00000006496|ensembl:ENSMUSP00000104265|uniprotkb:Q3UBF1|uniprotkb:Q8K2D1	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rs9_mouse(display_long)|uniprotkb:Rps9(gene name)|psi-mi:Rps9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000006333(gene)|ensembl:ENSMUST00000006496(transcript)|ensembl:ENSMUST00000108625(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_084043.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q6ZQ38	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-597255|uniprotkb:Q6PFR0|uniprotkb:Q9CV45|ensembl:ENSMUSP00000020315	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cand1_mouse(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:Cand1(gene name)|psi-mi:Cand1(display_short)|uniprotkb:D10Ertd516e(gene name synonym)|uniprotkb:Kiaa0829(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_082270.1|ensembl:ENSMUSG00000020114(gene)|ensembl:ENSMUST00000020315(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:Q6ZQ38|reactome:R-MMU-6798695|reactome:R-MMU-8951664|reactome:R-MMU-917937	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:E6bJujLfT/V3C8Iyk0hUD1m4gT010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BWT1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1634016|uniprotkb:Q8JZR8|intact:EBI-4285676|uniprotkb:Q3TIT9|ensembl:ENSMUSP00000037348	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:thim_mouse(display_long)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acaa2(gene name)|psi-mi:Acaa2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_803421.1|ensembl:ENSMUSG00000036880(gene)|ensembl:ENSMUST00000041053(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q8BWT1|reactome:R-MMU-77289	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:15aWO97WJBNGYD449bAgjVjkgTY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P68254	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-400675|uniprotkb:P35216|uniprotkb:Q3TW69|uniprotkb:Q3UJN5|uniprotkb:Q5SP76|uniprotkb:Q5U423|uniprotkb:Q66JR6|ensembl:ENSMUSP00000100067|ensembl:ENSMUSP00000123605	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:1433t_mouse(display_long)|uniprotkb:Ywhaq(gene name)|psi-mi:Ywhaq(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035869.1|ensembl:ENSMUSG00000076432(gene)|ensembl:ENSMUST00000103002(transcript)|ensembl:ENSMUST00000135088(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P68254|reactome:R-MMU-111447|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9614399	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:l8bki6QJJEH5S5NIwQdm/MAYcc010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BFR5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299611|ensembl:ENSMUSP00000095656|uniprotkb:Q497E7|uniprotkb:Q6P919	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:eftu_mouse(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000073838(gene)|ensembl:ENSMUST00000098048(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:Q8BFR5|go:"GO:0042645"(mitochondrial nucleoid)|refseq:NP_001157185.1|refseq:NP_766333.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ax4f72KkJMxjxZD3ZClHh/oby3k10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q91VA7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773408|ensembl:ENSMUSP00000028892	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q91va7_mouse(display_long)|uniprotkb:Idh3b(gene name)|psi-mi:Idh3b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_570954.1|ensembl:ENSMUSG00000027406(gene)|ensembl:ENSMUST00000028892(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q91VA7|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:d7ckzD+a/x+uD5i8Sx1YHO8FQGY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8CAQ8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-776087|uniprotkb:Q66JS4|uniprotkb:Q7TNE2|uniprotkb:Q8C7V1|uniprotkb:Q8CCI0|uniprotkb:Q8CDA8|uniprotkb:Q9D9F6|ensembl:ENSMUSP00000066181	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mic60_mouse(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:Immt(gene name)|psi-mi:Immt(display_short)|uniprotkb:Mic60(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_083949.2|refseq:NP_001240617.1|refseq:NP_001240610.1|refseq:NP_001240616.1|dip:DIP-32050N|ensembl:ENSMUSG00000052337(gene)|ensembl:ENSMUST00000064062(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|mint:Q8CAQ8|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042407"(cristae formation)|go:"GO:0043209"(myelin sheath)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:fW23bvuLqjLn5wIOu6ycDsh7O1k10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P51912	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20566009|uniprotkb:Q61326	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:aaat_mouse(display_long)|uniprotkb:"ASC-like Na(+)-dependent neutral amino acid transporter ASCT2"(gene name synonym)|uniprotkb:Insulin-activated amino acid transporter(gene name synonym)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym)|uniprotkb:Slc1a5(gene name)|psi-mi:Slc1a5(display_short)|uniprotkb:Aaat(gene name synonym)|uniprotkb:Asct2(gene name synonym)|uniprotkb:Slc1a7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	reactome:R-MMU-352230|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|go:"GO:0005886"(plasma membrane)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015825"(L-serine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042470"(melanosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|reactome:R-MMU-9013149|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013423	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:mdG0+70GS4uPxJo62VmD9uH4JAk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P48678	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299212|ensembl:ENSMUSP00000029699|uniprotkb:P11516|uniprotkb:P97859|uniprotkb:Q3TIH0|uniprotkb:Q3TTS8|uniprotkb:Q3UCA0|uniprotkb:Q3UCJ8|uniprotkb:Q91WF2|uniprotkb:Q9DC21|uniprotkb:B3RH23|uniprotkb:B3RH24|uniprotkb:Q3U733|uniprotkb:Q3U7I5|uniprotkb:Q3UCU3	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:lmna_mouse(display_long)|uniprotkb:Lmna(gene name)|psi-mi:Lmna(display_short)|uniprotkb:Lmn1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|ensembl:ENSMUSG00000028063(gene)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|ensembl:ENSMUST00000029699(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1904178"(negative regulation of adipose tissue development)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P48678|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|rcsb pdb:1UFG|reactome:R-MMU-352238|reactome:R-MMU-4419969|refseq:NP_001002011.2|refseq:NP_001104572.1|refseq:NP_062263.1|refseq:XP_006501136.1|dip:DIP-31384N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:bJz9o/dZoD9E4CRP1FLYihybpwA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BMF4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-769141|uniprotkb:Q8K2G8|uniprotkb:Q8R339|uniprotkb:Q91ZB1|ensembl:ENSMUSP00000034567	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:odp2_mouse(display_long)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:Dlat(gene name)|psi-mi:Dlat(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_663589.3|ensembl:ENSMUSG00000000168(gene)|ensembl:ENSMUST00000034567(transcript)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030431"(sleep)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:Q8BMF4|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:I0x+9L5a4O6Bch+NFbNzYiONj+810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8VDC1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-16727814|ensembl:ENSMUSP00000081764|ensembl:ENSMUSP00000133222|uniprotkb:Q3V385|uniprotkb:Q7TMT0|uniprotkb:Q8BJN2	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:fyco1_mouse(display_long)|uniprotkb:Fyco1(gene name)|psi-mi:Fyco1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000025241(gene)|ensembl:ENSMUST00000084715(transcript)|ensembl:ENSMUST00000167595(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR004012(RUN)|interpro:IPR009038(GOLD)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR036598|interpro:IPR037213|interpro:IPR042654|rcsb pdb:5WRD|refseq:NP_001103723.2|refseq:NP_683727.3|refseq:XP_017168648.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:UQrU+0SySU+oBd+pE2OneGw0oog10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P47857	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773630|uniprotkb:O35513|uniprotkb:Q543L1|uniprotkb:Q9JK94|uniprotkb:C8CMN5|uniprotkb:C8CMN6|uniprotkb:C8CMN7|ensembl:ENSMUSP00000059801|ensembl:ENSMUSP00000132803|ensembl:ENSMUSP00000155809	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:pfkam_mouse(display_long)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme A(gene name synonym)|uniprotkb:Pfkm(gene name)|psi-mi:Pfkm(display_short)|uniprotkb:Pfka(gene name synonym)|uniprotkb:Pfk-m(gene name synonym)|uniprotkb:6-phosphofructokinase type A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001156959.1|refseq:NP_001156960.1|refseq:NP_067489.3|refseq:XP_006520664.1|refseq:XP_006520665.1|ensembl:ENSMUSG00000033065(gene)|ensembl:ENSMUST00000051226(transcript)|ensembl:ENSMUST00000163507(transcript)|ensembl:ENSMUST00000230445(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008443"(phosphofructokinase activity)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0093001"(glycolysis from storage polysaccharide through glucose-1-phosphate)|go:"GO:0097228"(sperm principal piece)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P47857|reactome:R-MMU-70171	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:8pCfLb1VVqpKN2d+zr7NCnhWRBk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P07901	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-78930|ensembl:ENSMUSP00000021698|ensembl:ENSMUSP00000091921	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hs90a_mouse(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hsp86(gene name synonym)|uniprotkb:Hsp86-1(gene name synonym)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 86 kDa antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034610.1|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07901|rcsb pdb:5H22|reactome:R-MMU-1227986|reactome:R-MMU-1474151|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-203615|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-399954|reactome:R-MMU-4420097|reactome:R-MMU-5218920|reactome:R-MMU-5620912|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8863795|reactome:R-MMU-8939211|reactome:R-MMU-9009391|reactome:R-MMU-9013418|reactome:R-MMU-9018519|reactome:R-MMU-9652282|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|ensembl:ENSMUSG00000021270(gene)|ensembl:ENSMUST00000021698(transcript)|ensembl:ENSMUST00000094361(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042026"(protein refolding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|dip:DIP-30975N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:t9XAeXdXezYOtJX0wp3IY9/ZMkQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P62855	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6260985|ensembl:ENSMUSP00000026420|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:P02383	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rs26_mouse(display_long)|uniprotkb:Rps26(gene name)|psi-mi:Rps26(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000025362(gene)|ensembl:ENSMUST00000026420(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|mint:P62855|refseq:NP_038793.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8QZT1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773036|uniprotkb:Q3TE92|ensembl:ENSMUSP00000034547	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:thil_mouse(display_long)|uniprotkb:Acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:Acat1(gene name)|psi-mi:Acat1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_659033.1|ensembl:ENSMUSG00000032047(gene)|ensembl:ENSMUST00000034547(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007420"(brain development)|go:"GO:0009725"(response to hormone)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016453"(C-acetyltransferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046356"(acetyl-CoA catabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0072229"(metanephric proximal convoluted tubule development)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1902860"(propionyl-CoA biosynthetic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q8QZT1|reactome:R-MMU-70895|reactome:R-MMU-77108|reactome:R-MMU-77111	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:nnHjpqiL4kor9wZWnMfHtun87EQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3TIU7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565992	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3tiu7_mouse(display_long)|uniprotkb:Ndufs1(gene name)|psi-mi:Ndufs1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR036010|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR019574|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:hhF1U1cattqy2cYNEP4gAUOc/4M10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8CIB5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-5545618|uniprotkb:Q8C542|uniprotkb:Q8K035|ensembl:ENSMUSP00000044554	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ferm2_mouse(display_long)|uniprotkb:Fermt2(gene name)|psi-mi:Fermt2(display_short)|uniprotkb:Plekhc1(gene name synonym)|uniprotkb:Kindlin-2(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_666166.2|ensembl:ENSMUSG00000037712(gene)|ensembl:ENSMUST00000045905(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0072657"(protein localization to membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1902462"(positive regulation of mesenchymal stem cell proliferation)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR037837|interpro:IPR037843|interpro:IPR040790|mint:Q8CIB5|rcsb pdb:5XPY|rcsb pdb:5XPZ|rcsb pdb:5XQ0|rcsb pdb:5XQ1|reactome:R-MMU-446353|reactome:R-MMU-9013149|reactome:R-MMU-9013423|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031674"(I band)|go:"GO:0033622"(integrin activation)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035505"(positive regulation of myosin light chain kinase activity)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060173"(limb development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:1WbgMzUL/oPRTZFx+71FShJbDq010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P82350	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565959|uniprotkb:O35311|uniprotkb:O88490|ensembl:ENSMUSP00000098118|ensembl:ENSMUSP00000099451|ensembl:ENSMUSP00000130617	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sgca_mouse(display_long)|uniprotkb:50 kDa dystrophin-associated glycoprotein(gene name synonym)|uniprotkb:Adhalin(gene name synonym)|uniprotkb:Sgca(gene name)|psi-mi:Sgca(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033187.1|refseq:XP_011247138.1|ensembl:ENSMUSG00000001508(gene)|ensembl:ENSMUST00000100551(transcript)|ensembl:ENSMUST00000103162(transcript)|ensembl:ENSMUST00000166320(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045121"(membrane raft)|go:"GO:0061024"(membrane organization)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008908(Sarcoglycan alphaepsilon)|interpro:IPR015919(Cadherin-like)|interpro:IPR028658	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:OdpMfSbJh/qdwV/gMqg+q/pwSWk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P56135	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6665643|ensembl:ENSMUSP00000125504|uniprotkb:Q3THX9|uniprotkb:Q9JMF4	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:atpk_mouse(display_long)|uniprotkb:Atp5mf(gene name)|psi-mi:Atp5mf(display_short)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)|uniprotkb:Atp5j2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000038690(gene)|ensembl:ENSMUST00000161741(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR019344|mint:P56135|reactome:R-MMU-163210|reactome:R-MMU-8949613|go:"GO:0046034"(ATP metabolic process)|refseq:NP_065607.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:wlieiI/2O2bOHbIJ4+Nh5IZIclY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CZB4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565951	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q9czb4_mouse(display_long)|uniprotkb:Apool(gene name)|psi-mi:Apool(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR019166|interpro:IPR033182|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:qch/LSZPhgI4hwNOxtjrusP9Sd010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P62204	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-397460|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q3TEH7|uniprotkb:Q3THK5|uniprotkb:Q3U6Z5|uniprotkb:Q3U7C7|uniprotkb:Q498A3|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q8BNC9|uniprotkb:Q91VQ9|uniprotkb:Q9D6G4|dip:DIP-31550N|uniprotkb:P0DP26|uniprotkb:P0DP28	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:calm_mouse(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:Cam(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	rcsb pdb:3WFN|rcsb pdb:4HEX|go:"GO:0005509"(calcium ion binding)|go:"GO:0000922"(spindle pole)|refseq:NP_031615.1|refseq:NP_031616.1|refseq:NP_033920.1|rcsb pdb:2IX7|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:2DFS|refseq:NP_001300863.1|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0043388"(positive regulation of DNA binding)|reactome:R-MMU-2672351|reactome:R-MMU-418359|reactome:R-MMU-425561|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0005829"(cytosol)|reactome:R-MMU-8876725|rcsb pdb:4E50|rcsb pdb:4E53|go:"GO:0061024"(membrane organization)|rcsb pdb:4ZLK|reactome:R-MMU-1445148|reactome:R-MMU-5576892|ensembl:ENSMUST00000019514|ensembl:ENSMUST00000040440|ensembl:ENSMUST00000110082|reactome:R-MMU-111932|reactome:R-MMU-111933|reactome:R-MMU-111957|reactome:R-MMU-114608|reactome:R-MMU-1474151|reactome:R-MMU-1855204|reactome:R-MMU-203615|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-442717|reactome:R-MMU-442729|reactome:R-MMU-442745|reactome:R-MMU-442982|reactome:R-MMU-445355|reactome:R-MMU-451308|reactome:R-MMU-5607763|reactome:R-MMU-5626467|reactome:R-MMU-5218920|reactome:R-MMU-5627123|reactome:R-MMU-5673001|reactome:R-MMU-70221|ensembl:ENSMUSG00000001175|ensembl:ENSMUSG00000019370|ensembl:ENSMUSG00000036438|ensembl:ENSMUSP00000019514|ensembl:ENSMUSP00000048857|ensembl:ENSMUSP00000105709|reactome:R-MMU-2514859|reactome:R-MMU-163615|go:"GO:0034704"(calcium channel complex)|go:"GO:0005813"(centrosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0030426"(growth cone)|go:"GO:0005634"(nucleus)|go:"GO:0030017"(sarcomere)|go:"GO:0005876"(spindle microtubule)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0002027"(regulation of heart rate)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|go:"GO:0021762"(substantia nigra development)|rcsb pdb:1UP5|go:"GO:1902494"(catalytic complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0043209"(myelin sheath)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031432"(titin binding)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|reactome:R-MMU-2025928|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0005886"(plasma membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0090151"(establishment of protein localization to mitochondrial membrane)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0051300"(spindle pole body organization)|interpro:IPR039030	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:tTYcOd9bOh211njZVz7cYVybAMQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9WV02	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6393090|ensembl:ENSMUSP00000110374|ensembl:ENSMUSP00000110378|uniprotkb:Q8C2U6|uniprotkb:Q9R0Y0	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rbmx_mouse(display_long)|uniprotkb:Rbmx(gene name)|psi-mi:Rbmx(display_short)|uniprotkb:Hnrnpg(gene name synonym)|uniprotkb:Hnrpg(gene name synonym)|uniprotkb:Rbmxp1(gene name synonym)|uniprotkb:Rbmxrt(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000031134(gene)|ensembl:ENSMUST00000114726(transcript)|ensembl:ENSMUST00000114730(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9WV02|reactome:R-MMU-72163|reactome:R-MMU-72203|reactome:R-MMU-9013418|reactome:R-MMU-9013422|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273|refseq:NP_035382.1|refseq:NP_001160095.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ifrLkzQpL8VIx6Dmsc8SBVQzDSU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P62141	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-352338|uniprotkb:P37140|uniprotkb:Q3TBE5|uniprotkb:Q3TL90|uniprotkb:Q542E7|uniprotkb:Q8C285|uniprotkb:Q9DBY2|ensembl:ENSMUSP00000015100|ensembl:ENSMUSP00000144047	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:pp1b_mouse(display_long)|uniprotkb:Ppp1cb(gene name)|psi-mi:Ppp1cb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_766295.2|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62141|reactome:R-MMU-2565942|reactome:R-MMU-5625740|reactome:R-MMU-5627123|reactome:R-MMU-5673000|ensembl:ENSMUSG00000014956(gene)|ensembl:ENSMUST00000015100(transcript)|ensembl:ENSMUST00000201360(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:VtNJVyimeiEuRDDWtGswTqoSOH810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q76MZ3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-400413|ensembl:ENSMUSP00000007708	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:2aaa_mouse(display_long)|uniprotkb:Ppp2r1a(gene name)|psi-mi:Ppp2r1a(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_058587.1|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:Q76MZ3|rcsb pdb:2IAE|rcsb pdb:2PF4|rcsb pdb:3FGA|rcsb pdb:6EF4|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2995383|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-8854518|reactome:R-MMU-9648025|reactome:R-MMU-975957|ensembl:ENSMUSG00000007564(gene)|ensembl:ENSMUST00000007708(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051232"(meiotic spindle elongation)|dip:DIP-29429N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:0tnO11U1SNOOT46j23f7dim8O8k10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q61598	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6665490|ensembl:ENSMUSP00000152454|uniprotkb:Q541Z9|uniprotkb:Q8C530|uniprotkb:Q9D8M9	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:gdib_mouse(display_long)|uniprotkb:Gdi2(gene name)|psi-mi:Gdi2(display_short)|uniprotkb:Gdi3(gene name synonym)|uniprotkb:GDI-3(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:Q61598|reactome:R-MMU-6798695|reactome:R-MMU-8876198|ensembl:ENSMUSG00000021218(gene)|ensembl:ENSMUST00000223396(transcript)|refseq:NP_032138.3|dip:DIP-348N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:+ngZz9q02lDEdFO543w/yl6chgc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q60597	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773541|uniprotkb:Q3UDM7|uniprotkb:Q5DTI4|uniprotkb:Q5SVX7|uniprotkb:Q5SVX9|uniprotkb:Q6PFZ2|uniprotkb:Q80Y57|uniprotkb:Q8K0K7|uniprotkb:Q8K2Z3|uniprotkb:Q8R3M2|uniprotkb:Q91WP2|ensembl:ENSMUSP00000003461|ensembl:ENSMUSP00000099090	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:odo1_mouse(display_long)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:Ogdh(gene name)|psi-mi:Ogdh(display_short)|uniprotkb:Kiaa4192(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035086.2|refseq:XP_006514645.1|refseq:XP_006514646.1|refseq:XP_006514647.1|refseq:XP_006514648.1|refseq:NP_001239211.1|refseq:NP_001239212.1|refseq:NP_001239216.1|refseq:NP_001239217.1|refseq:XP_017169826.1|ensembl:ENSMUSG00000020456(gene)|ensembl:ENSMUST00000003461(transcript)|ensembl:ENSMUST00000101554(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q60597|rcsb pdb:3E2H|rcsb pdb:3TF7|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:6as/Sp5FTXpjU1BwjR7vJ6xcxuA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P99027	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6261122|ensembl:ENSMUSP00000101625|ensembl:ENSMUSP00000101626|ensembl:ENSMUSP00000081474|uniprotkb:Q9CQ99|uniprotkb:Q9CZJ8|uniprotkb:Q3TKY3	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rla2_mouse(display_long)|uniprotkb:Rplp2(gene name)|psi-mi:Rplp2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUST00000084434(transcript)|ensembl:ENSMUST00000106003(transcript)|ensembl:ENSMUST00000106004(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0045202"(synapse)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P99027|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000025508(gene)|refseq:XP_006536292.1|refseq:NP_080296.3	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:GYHP8hzpsOXoDDDnyOOBTMeIozg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3TCI7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565935	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3tci7_mouse(display_long)|uniprotkb:Ldha(gene name)|psi-mi:Ldha(display_short)|uniprotkb:Ldh1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR018177|interpro:IPR022383|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR036291|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0019752"(carboxylic acid metabolic process)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:MV7cT+vRMMkUrBbAbqMCxIlfXyw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q99KJ8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-776048|ensembl:ENSMUSP00000026479	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dctn2_mouse(display_long)|uniprotkb:Dynactin complex 50 kDa subunit(gene name synonym)|uniprotkb:50 kDa dynein-associated polypeptide(gene name synonym)|uniprotkb:p50 dynamitin(gene name synonym)|uniprotkb:Growth cone membrane protein 23-48K(gene name synonym)|uniprotkb:Dctn2(gene name)|psi-mi:Dctn2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_081427.1|ensembl:ENSMUSG00000025410(gene)|ensembl:ENSMUST00000026479(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q99KJ8|reactome:R-MMU-2132295|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-8854518	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:D7u4MT5Zl5mRBQ/zsTwhYP0WHoU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q6ZQ73	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6504831|ensembl:ENSMUSP00000075377|uniprotkb:Q6PHT7	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cand2_mouse(display_long)|uniprotkb:Cand2(gene name)|psi-mi:Cand2(display_short)|uniprotkb:Kiaa0667(gene name synonym)|uniprotkb:Tip120b(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000030319(gene)|ensembl:ENSMUST00000075995(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|refseq:NP_080234.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:OkTwdfaLvWK+edxRZnob8ShssWI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P14152	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-494462|uniprotkb:Q3TP22|uniprotkb:Q80Y13|uniprotkb:Q9DB45|ensembl:ENSMUSP00000099938|ensembl:ENSMUSP00000159017	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mdhc_mouse(display_long)|uniprotkb:Cytosolic malate dehydrogenase(gene name synonym)|uniprotkb:Mdh1(gene name)|psi-mi:Mdh1(display_short)|uniprotkb:Mor2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032644.3|refseq:NP_001303604.1|ensembl:ENSMUSG00000020321(gene)|ensembl:ENSMUST00000102874(transcript)|ensembl:ENSMUST00000239073(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0016615"(malate dehydrogenase activity)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0051287"(NAD binding)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010945(Malate dehydrogenase, NAD or NADP)|interpro:IPR011274(Malate dehydrogenase, NAD-dependent, cytosolic)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|go:"GO:0006108"(malate metabolic process)|interpro:IPR022383|interpro:IPR036291|mint:P14152|reactome:R-MMU-70263	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Yq74ALpVIoaMM9Y2LUS4Sdmfztg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:B0LAD0	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20564586	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:b0lad0_mouse(display_long)|uniprotkb:Eif3f(gene name)|psi-mi:Eif3f(display_short)|uniprotkb:Eif3s5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0031369"(translation initiation factor binding)|interpro:IPR027531	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Yf6S2BdZvV8Q8+Or2gT0upXdFF010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P43274	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-913424|ensembl:ENSMUSP00000057308|uniprotkb:Q5EBH3	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:h14_mouse(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1 VAR.2(gene name synonym)|uniprotkb:H1e(gene name synonym)|uniprotkb:H1f4(gene name synonym)|uniprotkb:Hist1h1e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000051627(gene)|ensembl:ENSMUST00000062045(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43274|reactome:R-MMU-140342|reactome:R-MMU-2559584|refseq:NP_056602.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:RbnBt0O11C8PWtfWp8tJJxsn00A10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P17427	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-775215|uniprotkb:Q8C2J5|uniprotkb:Q921V0|ensembl:ENSMUSP00000003038	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ap2a2_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031485.3|dip:DIP-32160N|ensembl:ENSMUSG00000002957(gene)|ensembl:ENSMUST00000003038(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030141"(secretory granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17427|rcsb pdb:1B9K|rcsb pdb:1KY6|rcsb pdb:1KY7|rcsb pdb:1KYD|rcsb pdb:1KYF|rcsb pdb:1KYU|rcsb pdb:1QTP|rcsb pdb:1QTS|rcsb pdb:1W80|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2VJ0|rcsb pdb:3HS8|rcsb pdb:6OWO|rcsb pdb:6OXL|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-6798695|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:KlOjm5d8qxxQkcuD2Hukoj8DLss10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A2AKD7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565907|ensembl:ENSMUSP00000105350	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P20108	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-309031|ensembl:ENSMUSP00000025961	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:prdx3_mouse(display_long)|uniprotkb:Prdx3(gene name)|psi-mi:Prdx3(display_short)|uniprotkb:Aop1(gene name synonym)|uniprotkb:Mer5(gene name synonym)|uniprotkb:Perioredoxin-3(gene name synonym)|uniprotkb:PRX III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000024997(gene)|ensembl:ENSMUST00000025961(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0043209"(myelin sheath)|go:"GO:0019900"(kinase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P20108|reactome:R-MMU-3299685|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|refseq:NP_031478.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:BGMQPun3/Vu7SSlj8rdWV+PU48Q10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q6PIE5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6665421|ensembl:ENSMUSP00000083077|uniprotkb:Q80UZ8	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:at1a2_mouse(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q6PIE5|reactome:R-MMU-5578775|reactome:R-MMU-936837|go:"GO:0098655"(cation transmembrane transport)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0040011"(locomotion)|ensembl:ENSMUSG00000007097(gene)|ensembl:ENSMUST00000085913(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0006814"(sodium ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|refseq:NP_848492.1|dip:DIP-48355N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D1G3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565883|uniprotkb:Q3TZE3|uniprotkb:Q8R1K3|ensembl:ENSMUSP00000035110|ensembl:ENSMUSP00000131971	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hhatl_mouse(display_long)|uniprotkb:Glycerol uptake/transporter homolog(gene name synonym)|uniprotkb:Hedgehog acyltransferase-like protein(gene name synonym)|uniprotkb:Hhatl(gene name)|psi-mi:Hhatl(display_short)|uniprotkb:Gup1(gene name synonym)|uniprotkb:Kiaa1173(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_083371.2|refseq:XP_006512442.1|refseq:XP_006512443.1|refseq:XP_006512444.1|ensembl:ENSMUSG00000032523(gene)|ensembl:ENSMUST00000035110(transcript)|ensembl:ENSMUST00000163981(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060262"(negative regulation of N-terminal protein palmitoylation)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|interpro:IPR032980	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:7n5Em+EucuLfZE+wmsCcLrEgams10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQQ7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2935050|ensembl:ENSMUSP00000113022	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:at5f1_mouse(display_long)|uniprotkb:Atp5pb(gene name)|psi-mi:Atp5pb(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:Atp5f1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000000563(gene)|ensembl:ENSMUST00000118209(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:Q9CQQ7|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_033855.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:g22oBc1YXUjxPlMIN/TbpQrIXEg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P14685	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-992014|uniprotkb:Q3TP95|uniprotkb:Q99LL7|ensembl:ENSMUSP00000017365	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:psmd3_mouse(display_long)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:Transplantation antigen P91A(gene name synonym)|uniprotkb:Tum-P91A antigen(gene name synonym)|uniprotkb:Tstap91a(gene name synonym)|uniprotkb:Psmd3(gene name)|psi-mi:Psmd3(display_short)|uniprotkb:P91a(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033465.1|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|reactome:R-MMU-5610785|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|reactome:R-MMU-1169091|reactome:R-MMU-5632684|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-5658442|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-5668541|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-5676590|reactome:R-MMU-2467813|reactome:R-MMU-5687128|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-6798695|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-68827|ensembl:ENSMUSG00000017221(gene)|ensembl:ENSMUST00000017365(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0042176"(regulation of protein catabolic process)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WUwE+HYUn3TfD5w+LPjn5ouQSCQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BZF8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565854|ensembl:ENSMUSP00000036025	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:pgm5_mouse(display_long)|uniprotkb:Pgm5(gene name)|psi-mi:Pgm5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_778178.3|ensembl:ENSMUSG00000041731(gene)|ensembl:ENSMUST00000047666(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0014706"(striated muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030018"(Z disc)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030239"(myofibril assembly)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|interpro:IPR005841(Alpha-D-phosphohexomutase, N-terminal)|interpro:IPR005844(Alpha-D-phosphohexomutase, alpha/beta/alpha domain I)|interpro:IPR005845(Alpha-D-phosphohexomutase, alpha/beta/alpha domain II)|interpro:IPR005846(Alpha-D-phosphohexomutase, alpha/beta/alpha domain III)|interpro:IPR016055(Alpha-D-phosphohexomutase, alpha/beta/alpha I, II and III)|interpro:IPR016066(Alpha-D-phosphohexomutase, conserved site)|interpro:IPR036900	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:9JXATnrJBJ3aQPiv+VSUxROnvYg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P12787	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934751|ensembl:ENSMUSP00000000090|uniprotkb:Q9D2W1	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cox5a_mouse(display_long)|uniprotkb:Cox5a(gene name)|psi-mi:Cox5a(display_short)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0043209"(myelin sheath)|go:"GO:0046872"(metal ion binding)|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P12787|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|ensembl:ENSMUSG00000000088(gene)|ensembl:ENSMUST00000000090(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|refseq:NP_031773.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:TSqMPwzrYDOAB4IRLwU8EcFKdY010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8K2B3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1219461|uniprotkb:Q0QF19|uniprotkb:Q3UH25|uniprotkb:Q3UKP7|uniprotkb:Q3V4B1|uniprotkb:Q921P5|uniprotkb:Q9Z1Z4|ensembl:ENSMUSP00000022062	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sdha_mouse(display_long)|uniprotkb:Sdha(gene name)|psi-mi:Sdha(display_short)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_075770.1|ensembl:ENSMUSG00000021577(gene)|ensembl:ENSMUST00000022062(transcript)|go:"GO:0000104"(succinate dehydrogenase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0043209"(myelin sheath)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|mint:Q8K2B3|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:DbI/pBVBwa3ezreOqH3hgGy1qkA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8CE08	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-10758309|uniprotkb:A4QPG2|uniprotkb:B8JJZ5|uniprotkb:B8JJZ6|uniprotkb:Q8C682|uniprotkb:Q9QXH7|ensembl:ENSMUSP00000108209	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ppap_mouse(display_long)|uniprotkb:Protein tyrosine phosphatase ACP3(gene name synonym)|uniprotkb:Fluoride-resistant acid phosphatase(gene name synonym)|uniprotkb:Acid phosphatase 3(gene name synonym)|uniprotkb:Acpp(gene name synonym)|uniprotkb:Ecto-5'-nucleotidase(gene name synonym)|uniprotkb:Thiamine monophosphatase(gene name synonym)|uniprotkb:Acp3(gene name)|psi-mi:Acp3(display_short)|uniprotkb:5'-nucleotidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_062781.2|refseq:NP_997551.1|ensembl:ENSMUSG00000032561(gene)|ensembl:ENSMUST00000112590(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030175"(filopodium)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0033265"(choline binding)|go:"GO:0042131"(thiamine phosphate phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045177"(apical part of cell)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0052642"(lysophosphatidic acid phosphatase activity)|go:"GO:0060168"(positive regulation of adenosine receptor signaling pathway)|interpro:IPR000560(Histidine acid phosphatase)|interpro:IPR029033|interpro:IPR033379|reactome:R-MMU-6798695|go:"GO:0030141"(secretory granule)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:qpuLrBgocld5m1xK9iKMlGBBIHw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A3KGU5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-4281668|ensembl:ENSMUSP00000109346	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a3kgu5_mouse(display_long)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000113717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|refseq:NP_001171139.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:yypmAHwRMgI24GzDP8yc1tbsaGs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A0T1J8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565836	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a0t1j8_mouse(display_long)|uniprotkb:Lmo7(gene name)|psi-mi:Lmo7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_963287.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR031865|interpro:IPR029978|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR003096(SM22/calponin)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0023051"(regulation of signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0042805"(actinin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:5bDREaTK+HDQYiunktDRtc3E3Mc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9QXS1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-774583|uniprotkb:Q9QXR8|uniprotkb:Q9QXR9|uniprotkb:Q6S384|uniprotkb:Q6S389|uniprotkb:Q6S394|uniprotkb:Q9CS65|uniprotkb:Q9QUT2|uniprotkb:Q9QXQ8|uniprotkb:Q9QXQ9|uniprotkb:Q9QXR0|uniprotkb:Q9QXR1|uniprotkb:Q9QXR2|uniprotkb:Q9QXR3|uniprotkb:Q9QXR4|uniprotkb:Q9QXR5|uniprotkb:Q9QXR6|uniprotkb:Q9QXR7|uniprotkb:Q9QXS0|uniprotkb:Q9QXS2|uniprotkb:Q9QXS3|uniprotkb:E9QN87|ensembl:ENSMUSP00000073124	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:plec_mouse(display_long)|uniprotkb:Plectin-6(gene name synonym)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001157012.1|refseq:NP_001157014.1|refseq:NP_001157021.1|refseq:NP_001157675.1|refseq:NP_035247.2|refseq:NP_958791.2|refseq:NP_958796.2|dip:DIP-32004N|ensembl:ENSMUSG00000022565(gene)|ensembl:ENSMUST00000073418(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0043588"(skin development)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071944"(cell periphery)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR018159|interpro:IPR030269|interpro:IPR035915|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q9QXS1|rcsb pdb:1SH5|rcsb pdb:1SH6|rcsb pdb:4Q57|reactome:R-MMU-264870|reactome:R-MMU-446107	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:9cGCRGhjImLIGd9shNPJRdSpdoY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D8N0	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773880|uniprotkb:Q920C5|uniprotkb:Q9CRT5|uniprotkb:Q9CSU3|uniprotkb:Q9D004|ensembl:ENSMUSP00000093955	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ef1g_mouse(display_long)|uniprotkb:eEF-1B gamma(gene name synonym)|uniprotkb:Eef1g(gene name)|psi-mi:Eef1g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0003746"(translation elongation factor activity)|dip:DIP-32124N|refseq:NP_080283.3|ensembl:ENSMUSG00000071644(gene)|ensembl:ENSMUST00000052248(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:Q9D8N0|reactome:R-MMU-156842	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:TsONpdlsFR2YmfxQmAH4ByI5/Bg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P42125	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565816|uniprotkb:Q8QZV3|ensembl:ENSMUSP00000157291	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:eci1_mouse(display_long)|uniprotkb:3,2-trans-enoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),Delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:Eci1(gene name)|psi-mi:Eci1(display_short)|uniprotkb:Dci(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034153.2|ensembl:ENSMUSG00000024132(gene)|ensembl:ENSMUST00000234304(transcript)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|go:"GO:0042802"(identical protein binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR029045|reactome:R-MMU-77288	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WQfWjTwgG5wX4lIQFsCerDiJD9s10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CPR4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6260896	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl17_mouse(display_long)|uniprotkb:Rpl17(gene name)|psi-mi:Rpl17(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|rcsb pdb:6SWA|mint:Q9CPR4|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:1O/Lf4KUmT/kaME3XavS27J+PGs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P43277	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299625|ensembl:ENSMUSP00000044395|uniprotkb:Q8C6M4	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:h13_mouse(display_long)|uniprotkb:H1-3(gene name)|psi-mi:H1-3(display_short)|uniprotkb:H1 VAR.4(gene name synonym)|uniprotkb:H1d(gene name synonym)|uniprotkb:H1f3(gene name synonym)|uniprotkb:Hist1h1d(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000052565(gene)|ensembl:ENSMUST00000045301(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43277|reactome:R-MMU-140342|go:"GO:0000786"(nucleosome)|reactome:R-MMU-2559584|go:"GO:0000791"(euchromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016584"(nucleosome positioning)|refseq:NP_663759.3	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:az/dCjeaJAf5G/5QRQeFE9Q63Ps10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P80316	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-772379|uniprotkb:Q3TIE0|uniprotkb:Q3U530|uniprotkb:Q3UCU4|uniprotkb:Q3UJK9|uniprotkb:Q3UWA9|uniprotkb:Q542K3|uniprotkb:Q6ZQJ1|ensembl:ENSMUSP00000022842	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tcpe_mouse(display_long)|uniprotkb:CCT-epsilon(gene name synonym)|uniprotkb:Cct5(gene name)|psi-mi:Cct5(display_short)|uniprotkb:Ccte(gene name synonym)|uniprotkb:Kiaa0098(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031663.1|refseq:NP_001334964.1|ensembl:ENSMUSG00000022234(gene)|ensembl:ENSMUST00000022842(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012718(T-complex protein 1, epsilon subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80316|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:UpEEjKLyd92Zl4VnOTTlziuwAGA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQV8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-771608|uniprotkb:O70455|uniprotkb:Q3TY33|uniprotkb:Q3UAN6|ensembl:ENSMUSP00000018470	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:1433b_mouse(display_long)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Ywhab(gene name)|psi-mi:Ywhab(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_061223.2|refseq:XP_006499972.1|reactome:R-MMU-111447|reactome:R-MMU-165159|reactome:R-MMU-166208|reactome:R-MMU-170968|reactome:R-MMU-2028269|reactome:R-MMU-392517|reactome:R-MMU-450385|reactome:R-MMU-450513|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5675221|reactome:R-MMU-75035|reactome:R-MMU-9614399|ensembl:ENSMUSG00000018326(gene)|ensembl:ENSMUST00000018470(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:4GNT|rcsb pdb:5F74|rcsb pdb:5WFU|rcsb pdb:5WFX	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:g94luGOxfq+Jbi0ztZ7gbAkp+2A10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P60335	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-309059|ensembl:ENSMUSP00000054863	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:pcbp1_mouse(display_long)|uniprotkb:Pcbp1(gene name)|psi-mi:Pcbp1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035995.1|ensembl:ENSMUSG00000051695(gene)|ensembl:ENSMUST00000053015(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008494"(translation activator activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P60335|reactome:R-MMU-72163|reactome:R-MMU-72203	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:x72fawo4plQ+ipfqIoREIDHc2bA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P53026	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773918	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl10a_mouse(display_long)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Rpl10a(gene name)|psi-mi:Rpl10a(display_short)|uniprotkb:Nedd6(gene name synonym)|uniprotkb:Nedd-6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR028364|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR023673|interpro:IPR023674|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|mint:P53026|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:hL4G0HJQ8H6+nUIVFXxy0Y1QXnQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q91YN9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-4281163|uniprotkb:Q3UMR7|ensembl:ENSMUSP00000042009	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:bag2_mouse(display_long)|uniprotkb:Bag2(gene name)|psi-mi:Bag2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000042215(gene)|ensembl:ENSMUST00000044691(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:Q91YN9|rcsb pdb:3CQX|rcsb pdb:3D0T|reactome:R-MMU-3371453|refseq:NP_663367.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Ml80SWS2aEOQRIzvRwO6yMYOKvM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9DB77	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773760|uniprotkb:Q8BK11|uniprotkb:Q9CVK7|ensembl:ENSMUSP00000033176	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:qcr2_mouse(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:Uqcrc2(gene name)|psi-mi:Uqcrc2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_080175.1|ensembl:ENSMUSG00000030884(gene)|ensembl:ENSMUST00000033176(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006508"(proteolysis)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:Q9DB77|reactome:R-MMU-611105	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:CTpkPoAK0EWa6sxA5LJY0srVn/s10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CZB0	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1219475|uniprotkb:Q544Q9|uniprotkb:Q99JP2|uniprotkb:Q9DCU7|ensembl:ENSMUSP00000106968	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:c560_mouse(display_long)|uniprotkb:Sdhc(gene name)|psi-mi:Sdhc(display_short)|uniprotkb:Integral membrane protein CII-3(gene name synonym)|uniprotkb:QPs-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_079597.2|ensembl:ENSMUSG00000058076(gene)|ensembl:ENSMUST00000111336(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000701(Succinate dehydrogenase, cytochrome b subunit)|interpro:IPR014314(Succinate dehydrogenase, cytochrome b556 subunit)|interpro:IPR018495|interpro:IPR034804|mint:Q9CZB0|reactome:R-MMU-71403|go:"GO:0006099"(tricarboxylic acid cycle)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:VbV/1kZHcWxr90aGmjeShg2XJRM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P14869	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-529949|uniprotkb:Q99L54|ensembl:ENSMUSP00000083705	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rla0_mouse(display_long)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Rplp0(gene name)|psi-mi:Rplp0(display_short)|uniprotkb:Arbp(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031501.1|ensembl:ENSMUSG00000067274(gene)|ensembl:ENSMUST00000086519(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042277"(peptide binding)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P14869|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WHl41TZwjtqRSeIExT3vyjrZsJs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P52480	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-647785|uniprotkb:Q3TBV8|uniprotkb:Q3TBW5|uniprotkb:Q3TC59|uniprotkb:Q3U1X3|uniprotkb:Q3U5P6|uniprotkb:Q4VC20|uniprotkb:Q64484|uniprotkb:Q91YI8|uniprotkb:Q9CWB1|ensembl:ENSMUSP00000034834	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:kpym_mouse(display_long)|uniprotkb:Pkm(gene name)|psi-mi:Pkm(display_short)|uniprotkb:Pk3(gene name synonym)|uniprotkb:Pkm2(gene name synonym)|uniprotkb:Pykm(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035229.2|refseq:XP_006510918.1|refseq:NP_001240812.1|refseq:XP_011240975.1|dip:DIP-40536N|ensembl:ENSMUSG00000032294(gene)|ensembl:ENSMUST00000034834(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001889"(liver development)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042866"(pyruvate biosynthetic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043531"(ADP binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1902912"(pyruvate kinase complex)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P52480|reactome:R-MMU-6798695|reactome:R-MMU-70171	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:SWQx3aPATcnlExhyy8afjcrB+xo10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3TIN2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565798	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3tin2_mouse(display_long)|uniprotkb:Qars(gene name)|psi-mi:Qars(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004514(Glutaminyl-tRNA synthetase, class Ic)|interpro:IPR007638(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 2)|interpro:IPR007639(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 1)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR020058|interpro:IPR020059|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|interpro:IPR042559|interpro:IPR042558	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:18v/NcXKckJvK3NaWUWsSLQIe5Y10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8R2G4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565772|uniprotkb:B2RUC2|uniprotkb:O54738|uniprotkb:Q8R2F9|uniprotkb:Q8R2G0|uniprotkb:Q8R2G1|uniprotkb:Q8R2G2|uniprotkb:Q8R2G3	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nar3_mouse(display_long)|uniprotkb:ADP-ribosyltransferase C2 and C3 toxin-like 3(gene name synonym)|uniprotkb:"Mono(ADP-ribosyl)transferase 3"(gene name synonym)|uniprotkb:"NAD(P)(+)--arginine ADP-ribosyltransferase 3"(gene name synonym)|uniprotkb:Art3(gene name)|psi-mi:Art3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001297594.1|refseq:NP_859417.2|refseq:XP_006534780.1|refseq:XP_006534781.1|reactome:R-MMU-163125|interpro:IPR000768("NAD:arginine ADP-ribosyltransferase, ART")|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0018120"(peptidyl-arginine ADP-ribosylation)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0106274"(NAD+-protein-arginine ADP-ribosyltransferase activity)|go:"GO:0106275"(NADP+-protein-arginine ADP-ribosyltransferase activity)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WoVPL+yGY3rtbtPORl5w280s42Y10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P70404	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773416|ensembl:ENSMUSP00000056502	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:idhg1_mouse(display_long)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)|uniprotkb:Idh3g(gene name)|psi-mi:Idh3g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032349.1|ensembl:ENSMUSG00000002010(gene)|ensembl:ENSMUST00000052761(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P70404|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:0wCp92dH0hTrNyYmucC9Ob73aBU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8K1M3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2931743|ensembl:ENSMUSP00000035220	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q8k1m3_mouse(display_long)|uniprotkb:Prkar2a(gene name)|psi-mi:Prkar2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0016301"(kinase activity)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0044853"(plasma membrane raft)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:Q8K1M3|ensembl:ENSMUSG00000032601(gene)|ensembl:ENSMUST00000035220(transcript)|refseq:NP_032950.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:x3JyL96ukOXZMw6spgA4CdElv6M10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q5FW75	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-9989889	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q5fw75_mouse(display_long)|uniprotkb:Actn2(gene name)|psi-mi:Actn2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|refseq:NP_150371.4|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|interpro:IPR036872	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:tHTCxcvdDKeWTHbEzCJKSqQIi3810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q80TN1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2933616	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q80tn1_mouse(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)|uniprotkb:mKIAA0968(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR032710	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ZM8ubS1DGmAavt+X7DT9zthvkn410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q62425	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299572|ensembl:ENSMUSP00000144932|ensembl:ENSMUSP00000145413|uniprotkb:Q9CQP6	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndua4_mouse(display_long)|uniprotkb:Ndufa4(gene name)|psi-mi:Ndufa4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000029632(gene)|ensembl:ENSMUST00000204714(transcript)|ensembl:ENSMUST00000204978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0022900"(electron transport chain)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:Q62425|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1MWA|rcsb pdb:2CKB|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|refseq:NP_035016.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:jHsaW6CL4Rm/cNbZXlwU02m7dlE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P35486	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773613|ensembl:ENSMUSP00000033662	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:odpa_mouse(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:Pdha1(gene name)|psi-mi:Pdha1(display_short)|uniprotkb:Pdha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032836.1|ensembl:ENSMUSG00000031299(gene)|ensembl:ENSMUST00000033662(transcript)|go:"GO:0004738"(pyruvate dehydrogenase activity)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0043209"(myelin sheath)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|interpro:IPR029061|mint:P35486|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:QIfCMikb5tVYwefUZs3+5ut/nbY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O08709	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P16045	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1634185|uniprotkb:P05163|uniprotkb:P11946|uniprotkb:P17601|uniprotkb:Q4FZH4|uniprotkb:Q99M27|uniprotkb:Q9D0X0|ensembl:ENSMUSP00000086795	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:leg1_mouse(display_long)|uniprotkb:Lgals1(gene name)|psi-mi:Lgals1(display_short)|uniprotkb:Gbp(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:Lactose-binding lectin 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032521.1|ensembl:ENSMUSG00000068220(gene)|ensembl:ENSMUST00000089377(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0005534"(galactose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P16045|rcsb pdb:4LBQ|reactome:R-MMU-381426|reactome:R-MMU-8957275	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:VMxhs6wVhql3NEex38RQeIwirZs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P84078	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2308190|uniprotkb:P10947|uniprotkb:P32889|uniprotkb:Q3THZ2|uniprotkb:Q3U849|uniprotkb:Q3UDG1|uniprotkb:Q3UF76|ensembl:ENSMUSP00000079905|ensembl:ENSMUSP00000126120	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:arf1_mouse(display_long)|uniprotkb:Arf1(gene name)|psi-mi:Arf1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001123880.1|refseq:NP_031502.1|ensembl:ENSMUSG00000048076(gene)|ensembl:ENSMUST00000061242(transcript)|ensembl:ENSMUST00000163300(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84078|rcsb pdb:1O3Y|rcsb pdb:2J59|reactome:R-MMU-1660499|reactome:R-MMU-1660514|reactome:R-MMU-199992|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811438	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:zray9asm6VonxpuJpv0dRBspPt810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q7TPR4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-774010|ensembl:ENSMUSP00000021554	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:actn1_mouse(display_long)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)|uniprotkb:Actn1(gene name)|psi-mi:Actn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_598917.1|ensembl:ENSMUSG00000015143(gene)|ensembl:ENSMUST00000021554(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030054"(cell junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0032127"(dense core granule membrane)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:Q7TPR4|rcsb pdb:6C0A|reactome:R-MMU-114608|reactome:R-MMU-446388|reactome:R-MMU-9013405|reactome:R-MMU-9013418|reactome:R-MMU-9035034	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:02QPrtqpFY8sgQvjRRI5wmCbNjU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P99029	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2735704|uniprotkb:Q9QX45|uniprotkb:Q9QZ75|ensembl:ENSMUSP00000025904	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:prdx5_mouse(display_long)|uniprotkb:Prdx5(gene name)|psi-mi:Prdx5(display_short)|uniprotkb:Prdx6(gene name synonym)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 2D-0014IV(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_036151.1|ensembl:ENSMUSG00000024953(gene)|ensembl:ENSMUST00000025904(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR036249|interpro:IPR037944|mint:P99029|reactome:R-MMU-3299685|reactome:R-MMU-5628897|interpro:IPR013766(Thioredoxin domain)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:uWS2EcAdupLmsVsQ6h1AV+vRffs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8K1M6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2365792|uniprotkb:Q8BNQ5|uniprotkb:Q8BQ64|uniprotkb:Q8CGD0|uniprotkb:Q8K1A1	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dnm1l_mouse(display_long)|uniprotkb:Dnm1l(gene name)|psi-mi:Dnm1l(display_short)|uniprotkb:Drp1(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001021118.1|refseq:XP_006522694.1|refseq:NP_001263269.1|refseq:NP_001263270.1|refseq:NP_690029.2|dip:DIP-54818N|mint:Q8K1M6|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|reactome:R-MMU-75153|go:"GO:0005903"(brush border)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:5yGX3+QNfz3+dKRHA2ffkIVq3yU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P68040	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-296749|ensembl:ENSMUSP00000020640|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-1183965|uniprotkb:Q3THP0|uniprotkb:Q3THY7|uniprotkb:Q3TKQ0|uniprotkb:Q3TW88|uniprotkb:Q5NCC5|uniprotkb:Q5NCC6|uniprotkb:Q9CSQ0|uniprotkb:Q9ERM6	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rack1_mouse(display_long)|uniprotkb:p205(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:12-3(gene name synonym)|uniprotkb:Gnb2-rs1(gene name synonym)|uniprotkb:Gnb2l1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Receptor for activated C kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P68040|reactome:R-MMU-5357905|reactome:R-MMU-5357956|reactome:R-MMU-5626978|go:"GO:0072344"(rescue of stalled ribosome)|ensembl:ENSMUSG00000020372(gene)|ensembl:ENSMUST00000020640(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008104"(protein localization)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0006412"(translation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|refseq:NP_032169.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q91WD5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-772751|uniprotkb:Q3U5Y9|uniprotkb:Q3UJX7|uniprotkb:Q99L23|uniprotkb:Q3TNA8|ensembl:ENSMUSP00000013737	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndus2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)|uniprotkb:Ndufs2(gene name)|psi-mi:Ndufs2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_694704.1|ensembl:ENSMUSG00000013593(gene)|ensembl:ENSMUST00000013737(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:Q91WD5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:dk8e26C1hIdTZvDnX5nE1n+juwk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P50136	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6877210	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:odba_mouse(display_long)|uniprotkb:Bckdha(gene name)|psi-mi:Bckdha(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|reactome:R-MMU-389661|reactome:R-MMU-70895|interpro:IPR034616|interpro:IPR001017(Dehydrogenase, E1 component)|mint:P50136|interpro:IPR029061	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:olIS4NX+013MFh25crNvKAUMkvw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9DCT2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-772758|uniprotkb:Q8BTZ3|uniprotkb:Q8R073|ensembl:ENSMUSP00000005647	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndus3_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym)|uniprotkb:Ndufs3(gene name)|psi-mi:Ndufs3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_080964.1|dip:DIP-32378N|ensembl:ENSMUSG00000005510(gene)|ensembl:ENSMUST00000005647(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016604"(nuclear body)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:Q9DCT2|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|reactome:R-MMU-9013408	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:2tQasToTy6/l6HeQwM+hTVH2Mow10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q61941	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-15184302|uniprotkb:Q9JK70	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nntm_mouse(display_long)|uniprotkb:Nnt(gene name)|psi-mi:Nnt(display_short)|uniprotkb:Nicotinamide nucleotide transhydrogenase(gene name synonym)|uniprotkb:Pyridine nucleotide transhydrogenase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	reactome:R-MMU-71403|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006740"(NADPH regeneration)|go:"GO:0008746"("NAD(P)+ transhydrogenase activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0050661"(NADP binding)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0051287"(NAD binding)|interpro:IPR008143(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2)|interpro:IPR008142(Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-1)|interpro:IPR007886(Alanine dehydrogenase/PNT, N-terminal)|interpro:IPR007698(Alanine dehydrogenase/PNT, C-terminal)|interpro:IPR029035|interpro:IPR026255|interpro:IPR024605|interpro:IPR034300|interpro:IPR036291	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Seas/Iqob55Q1juwFSGIZt/hqXs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P47911	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773947|uniprotkb:Q6P5I2|uniprotkb:Q925C3|ensembl:ENSMUSP00000031617	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl6_mouse(display_long)|uniprotkb:TAX-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Rpl6(gene name)|psi-mi:Rpl6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035420.2|refseq:XP_006530290.1|ensembl:ENSMUSG00000029614(gene)|ensembl:ENSMUST00000031617(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:P47911|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:rm/g3X/3zoauNoUW6K4M43n8e4810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P21550	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1634301|ensembl:ENSMUSP00000072620|ensembl:ENSMUSP00000104188|ensembl:ENSMUSP00000128714	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:enob_mouse(display_long)|uniprotkb:Eno3(gene name)|psi-mi:Eno3(display_short)|uniprotkb:Eno-3(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001129534.1|refseq:NP_031959.1|refseq:NP_001263214.1|refseq:XP_006532225.1|ensembl:ENSMUSG00000060600(gene)|ensembl:ENSMUST00000072841(transcript)|ensembl:ENSMUST00000108548(transcript)|ensembl:ENSMUST00000170716(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P21550|reactome:R-MMU-70171|reactome:R-MMU-70263	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:CN/5EMhCFqpjAxZ04UHwcLN+eRI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q06185	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6666496|ensembl:ENSMUSP00000051222|uniprotkb:P70342	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:atp5i_mouse(display_long)|uniprotkb:Atp5me(gene name)|psi-mi:Atp5me(display_short)|uniprotkb:Atp5i(gene name synonym)|uniprotkb:Atp5k(gene name synonym)|uniprotkb:Lfm-1(gene name synonym)|uniprotkb:Lfm1(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:Q06185|reactome:R-MMU-163210|reactome:R-MMU-8949613|ensembl:ENSMUSG00000050856(gene)|ensembl:ENSMUST00000049628(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|refseq:NP_031533.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:1hl0GhfM23wEB+OjR4PbmxMdNnQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9DCJ5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934656|ensembl:ENSMUSP00000065352|uniprotkb:A2AL45	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndua8_mouse(display_long)|uniprotkb:Ndufa8(gene name)|psi-mi:Ndufa8(display_short)|uniprotkb:Complex I-19kD(gene name synonym)|uniprotkb:Complex I-PGIV(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 19 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000026895(gene)|ensembl:ENSMUST00000070112(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR010625(CHCH)|interpro:IPR016680("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 8")|mint:Q9DCJ5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|refseq:NP_080979.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:OoUvtJiBjDUC1PWQeC3cwtwIBpc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P62242	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-351820|uniprotkb:P09058|uniprotkb:Q8C2G6|ensembl:ENSMUSP00000099757	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rs8_mouse(display_long)|uniprotkb:Rps8(gene name)|psi-mi:Rps8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033124.1|ensembl:ENSMUSG00000047675(gene)|ensembl:ENSMUST00000102696(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62242|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:3rpCBdQyRWR+TCKnupbnCp30jKE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P57780	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-445071|ensembl:ENSMUSP00000066068	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:actn4_mouse(display_long)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)|uniprotkb:Actn4(gene name)|psi-mi:Actn4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_068695.1|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P57780|reactome:R-MMU-114608|ensembl:ENSMUSG00000054808(gene)|ensembl:ENSMUST00000068045(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001725"(stress fiber)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030018"(Z disc)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902396"(protein localization to bicellular tight junction)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:IeHeXy0Cx5E6ivN3b8IxESBlhJI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P39447	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-79508|uniprotkb:E9QK00|ensembl:ENSMUSP00000099652	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:zo1_mouse(display_long)|uniprotkb:Tjp1(gene name)|psi-mi:Tjp1(display_short)|uniprotkb:Zo1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005516"(calmodulin binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0005634"(nucleus)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0005737"(cytoplasm)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0005829"(cytosol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0005921"(gap junction)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045471"(response to ethanol)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0071000"(response to magnetism)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0071253"(connexin binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:0014704"(intercalated disc)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:0016020"(membrane)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035597|interpro:IPR036028|interpro:IPR036034|mint:P39447|rcsb pdb:2RRM|reactome:R-MMU-191650|reactome:R-MMU-2028269|reactome:R-MMU-351906|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|ensembl:ENSMUSG00000030516(gene)|ensembl:ENSMUST00000102592(transcript)|go:"GO:0001825"(blastocyst formation)|refseq:NP_033412.2|dip:DIP-30946N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:wvslyL15GCrtwUReZEC9DiNvPEk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D6J5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934391|ensembl:ENSMUSP00000026222|uniprotkb:Q9D6M7	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndub8_mouse(display_long)|uniprotkb:Ndufb8(gene name)|psi-mi:Ndufb8(display_short)|uniprotkb:Complex I-ASHI(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase ASHI subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000025204(gene)|ensembl:ENSMUST00000026222(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008699(NADH-ubiquinone oxidoreductase ASHI subunit)|interpro:IPR016551("NADH dehydrogenase [ubiquinone] (complex I), beta subcomplex, subunit 8")|mint:Q9D6J5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-1268020|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_080337.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:haHI1mKizIPRzFQxhFoJShL4eO410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q78IK2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934077|ensembl:ENSMUSP00000093713|ensembl:ENSMUSP00000157712|ensembl:ENSMUSP00000158514|ensembl:ENSMUSP00000158561|uniprotkb:Q9ER48	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:atpmk_mouse(display_long)|uniprotkb:Atp5mk(gene name)|psi-mi:Atp5mk(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:Atp5md(gene name synonym)|uniprotkb:Dapit(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:Usmg5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000071528(gene)|ensembl:ENSMUST00000096014(transcript)|ensembl:ENSMUST00000235771(transcript)|ensembl:ENSMUST00000236170(transcript)|ensembl:ENSMUST00000237720(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|refseq:NP_075700.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:X/LBFKOsDisU3OvbILnMxEfWtNY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P50462	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299294|ensembl:ENSMUSP00000032658|ensembl:ENSMUSP00000129378	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:csrp3_mouse(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P50462|ensembl:ENSMUSG00000030470(gene)|ensembl:ENSMUST00000032658(transcript)|ensembl:ENSMUST00000167786(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_001185770.1|refseq:NP_038836.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:EbPKIwE6y1DIHlksFKgyAulACW810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P67778	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-298507|uniprotkb:P24142|uniprotkb:Q3UB75|uniprotkb:Q5SQG4|ensembl:ENSMUSP00000119603	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:phb_mouse(display_long)|uniprotkb:Phb(gene name)|psi-mi:Phb(display_short)|uniprotkb:B-cell receptor-associated protein 32(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000038845(gene)|ensembl:ENSMUST00000125172(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045471"(response to ethanol)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P67778|reactome:R-MMU-5673000|reactome:R-MMU-8949664|refseq:NP_032857.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:eUStcZ9Mu7+7MHr/GJXFwwJY/Fc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P23927	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P03911	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934562|ensembl:ENSMUSP00000081000	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nu4m_mouse(display_long)|uniprotkb:Mtnd4(gene name)|psi-mi:Mtnd4(display_short)|uniprotkb:mt-Nd4(gene name synonym)|uniprotkb:Nd4(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035094"(response to nicotine)|go:"GO:0045471"(response to ethanol)|go:"GO:0048039"(ubiquinone binding)|interpro:IPR000260(NADH-ubiquinone oxidoreductase chain 4, N-terminal)|interpro:IPR001750("NADH/Ubiquinone/plastoquinone (complex I)")|interpro:IPR003918(NADH-ubiquinone oxidoreductase, chain 4)|interpro:IPR010227(Proton-translocating NADH-quinone oxidoreductase, chain M)|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|go:"GO:0021549"(cerebellum development)|reactome:R-MMU-611105|reactome:R-MMU-6799198|ensembl:ENSMUSG00000064363(gene)|ensembl:ENSMUST00000082414(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007568"(aging)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|refseq:NP_904337.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WRCNqlPCKDHbK0/8yYNaICAGjgE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3TYK4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-9987718	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3tyk4_mouse(display_long)|uniprotkb:Prkar1a(gene name)|psi-mi:Prkar1a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0005886"(plasma membrane)|go:"GO:0030552"(cAMP binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR018490|interpro:IPR018488|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:XP_006532572.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:jCZTRD9RmEMm9kQHJ16s1UQNqSw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQZ5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934524|ensembl:ENSMUSP00000023085	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndua6_mouse(display_long)|uniprotkb:Ndufa6(gene name)|psi-mi:Ndufa6(display_short)|uniprotkb:Complex I-B14(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B14 subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000022450(gene)|ensembl:ENSMUST00000023085(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR008011(Complex 1 LYR protein)|interpro:IPR016488("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 6")|mint:Q9CQZ5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_080263.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:zZHhKN0VBIsBvrOUDV4/cytBPr410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A8DUK2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565759	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a8duk2_mouse(display_long)|uniprotkb:Hbbt1(gene name)|psi-mi:Hbbt1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR000971(Globin, subset)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR002337(Haemoglobin, beta)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:afk3+W9BW+Z4rQMp7wm99fgy1L010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3UH68	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-16731192|ensembl:ENSMUSP00000098723|uniprotkb:Q6DIC3|uniprotkb:Q80TK1	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:limc1_mouse(display_long)|uniprotkb:Limch1(gene name)|psi-mi:Limch1(display_short)|uniprotkb:Kiaa1102(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000037736(gene)|ensembl:ENSMUST00000101164(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032034"(myosin II head/neck binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001997(Calponin)|interpro:IPR029980|interpro:IPR031865|interpro:IPR036872|mint:Q3UH68|refseq:NP_001001980.2|refseq:NP_001243051.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:P8I5hZ1jOyZUpClXSiMeTpic7AQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P09411	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1634776|uniprotkb:Q3TPE6|uniprotkb:Q3UKV8|uniprotkb:Q5XJE7|ensembl:ENSMUSP00000080302	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:pgk1_mouse(display_long)|uniprotkb:Pgk1(gene name)|psi-mi:Pgk1(display_short)|uniprotkb:Pgk-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032854.2|dip:DIP-51710N|ensembl:ENSMUSG00000062070(gene)|ensembl:ENSMUST00000081593(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P09411|rcsb pdb:4O3F|reactome:R-MMU-70171|reactome:R-MMU-70263	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:388hPtU1n0xYbopG53ZWslYTzuk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A6H663	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-9987195	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a6h663_mouse(display_long)|uniprotkb:Bag3(gene name)|psi-mi:Bag3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0051087"(chaperone binding)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:xdE25m8ClXN+W57r6hTmYtW7JEs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A8DUK7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565746	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a8duk7_mouse(display_long)|uniprotkb:Hbbt1(gene name)|psi-mi:Hbbt1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR000971(Globin, subset)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR002337(Haemoglobin, beta)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:cJXu91/136+2tk/Q+bu7ytZwKwA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q7TMF3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934615|ensembl:ENSMUSP00000020209|uniprotkb:Q3TIA0	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nduac_mouse(display_long)|uniprotkb:Ndufa12(gene name)|psi-mi:Ndufa12(display_short)|uniprotkb:Complex I-B17.2(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase subunit B17.2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUST00000020209(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|interpro:IPR007763("NADH:ubiquinone oxidoreductase 17.2 kD subunit")|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|ensembl:ENSMUSG00000020022(gene)|refseq:NP_079827.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ABTsOaXBN3GSTwTETzzEvOfVMiQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P20152	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid://GDvGAXOR4hUXNtVpnZefex5v410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9QXX4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-775952|uniprotkb:Q9CZF6|uniprotkb:Q9DCF5|ensembl:ENSMUSP00000015256|ensembl:ENSMUSP00000139571	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cmc2_mouse(display_long)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)|uniprotkb:Slc25a13(gene name)|psi-mi:Slc25a13(display_short)|uniprotkb:Aralar2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001171043.1|refseq:NP_056644.1|ensembl:ENSMUSG00000015112(gene)|ensembl:ENSMUST00000015256(transcript)|ensembl:ENSMUST00000188414(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9QXX4|reactome:R-MMU-70263|reactome:R-MMU-8963693	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:c7qSgch4lV/J3PGriiqzNknznm010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9JMH9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-643214|uniprotkb:Q3TBB2|uniprotkb:Q3UH48|uniprotkb:Q3UV60|uniprotkb:Q5SYN8|uniprotkb:Q5SYN9|uniprotkb:Q5SYP0|uniprotkb:Q5SYP1|uniprotkb:Q811D7|ensembl:ENSMUSP00000104012|uniprotkb:Q5QD54|uniprotkb:Q5QD55|uniprotkb:Q5QD56	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:my18a_mouse(display_long)|uniprotkb:Myosin containing a PDZ domain(gene name synonym)|uniprotkb:Molecule associated with JAK3 N-terminus(gene name synonym)|uniprotkb:Myo18a(gene name)|psi-mi:Myo18a(display_short)|uniprotkb:Myspdz(gene name synonym)|uniprotkb:Surfactant protein receptor SP-R210(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035716.1|refseq:XP_006533667.1|refseq:XP_006533669.1|refseq:XP_006533677.2|refseq:NP_001278141.1|refseq:NP_001278142.1|refseq:NP_001278143.1|refseq:NP_001278144.1|go:"GO:0005903"(brush border)|go:"GO:0007030"(Golgi organization)|go:"GO:0016459"(myosin complex)|go:"GO:0016477"(cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043531"(ADP binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048194"(Golgi vesicle budding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090164"(asymmetric Golgi ribbon formation)|go:"GO:1903028"(positive regulation of opsonization)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR027417|interpro:IPR031244|interpro:IPR036034|interpro:IPR036064|interpro:IPR036961|mint:Q9JMH9|ensembl:ENSMUSG00000000631(gene)|ensembl:ENSMUST00000108375(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005524"(ATP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005856"(cytoskeleton)|refseq:XP_017170115.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:TZQzZ2x1aphZBaHL6GPOTcdJzco10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P40142	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-494230|uniprotkb:Q3U7Y1|uniprotkb:Q3UK62|uniprotkb:Q545A1|uniprotkb:Q9ESA0|ensembl:ENSMUSP00000022529	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tkt_mouse(display_long)|uniprotkb:P68(gene name synonym)|uniprotkb:Tkt(gene name)|psi-mi:Tkt(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033414.1|ensembl:ENSMUSG00000021957(gene)|ensembl:ENSMUST00000022529(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004802"(transketolase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0016604"(nuclear body)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0048029"(monosaccharide binding)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|mint:P40142|reactome:R-MMU-163754|reactome:R-MMU-71336	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:h2YT3KKVrgDmPcSbJmtevBv1CAI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P17426	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-775189|ensembl:ENSMUSP00000082519|ensembl:ENSMUSP00000127842	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ap2a1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Ap2a1(gene name)|psi-mi:Ap2a1(display_short)|uniprotkb:Adtaa(gene name synonym)|uniprotkb:Clapa1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001070732.1|refseq:NP_031484.1|ensembl:ENSMUSG00000060279(gene)|ensembl:ENSMUST00000085399(transcript)|ensembl:ENSMUST00000166972(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0032433"(filopodium tip)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17426|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Dd6Q+Et/LTlmo5qpro2Zaeq0dMc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9JK42	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-643530|uniprotkb:Q8VC63|ensembl:ENSMUSP00000041447	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:pdk2_mouse(display_long)|uniprotkb:Pyruvate dehydrogenase kinase isoform 2(gene name synonym)|uniprotkb:Pdk2(gene name)|psi-mi:Pdk2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_598428.2|ensembl:ENSMUSG00000038967(gene)|ensembl:ENSMUST00000038431(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006885"(regulation of pH)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010510"(regulation of acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0010565"(regulation of cellular ketone metabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR018955|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:Q9JK42|reactome:R-MMU-204174|reactome:R-MMU-5362517|interpro:IPR005467(Signal transduction histidine kinase, core)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:D23zOk9wYjzMwMQYSgquxlE6XVc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q60932	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299577|ensembl:ENSMUSP00000020673|uniprotkb:Q5SVC6|uniprotkb:B1ASZ9	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:vdac1_mouse(display_long)|uniprotkb:Vdac1(gene name)|psi-mi:Vdac1(display_short)|uniprotkb:Vdac5(gene name synonym)|uniprotkb:Voltage-dependent anion-selective channel protein 5(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0001662"(behavioral fear response)|go:"GO:0005253"(anion channel activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|ensembl:ENSMUSG00000020402(gene)|ensembl:ENSMUST00000020673(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:Q60932|rcsb pdb:3EMN|rcsb pdb:4C69|rcsb pdb:7KUH|reactome:R-MMU-5205685|reactome:R-MMU-5689880|reactome:R-MMU-70268|go:"GO:0042802"(identical protein binding)|refseq:NP_035824.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:bULLXFpcR97WYvb2Pc7kDU9n31w10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CPU4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2935061|uniprotkb:Q3UXC5|uniprotkb:Q9D834|ensembl:ENSMUSP00000028005	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mgst3_mouse(display_long)|uniprotkb:Mgst3(gene name)|psi-mi:Mgst3(display_short)|uniprotkb:Glutathione peroxidase MGST3(gene name synonym)|uniprotkb:Microsomal glutathione S-transferase III(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0004464"(leukotriene-C4 synthase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001129("Membrane-associated, eicosanoid and glutathione metabolism (MAPEG)")|interpro:IPR023352|reactome:R-MMU-156590|reactome:R-MMU-5423646|go:"GO:0004364"(glutathione transferase activity)|ensembl:ENSMUSG00000026688(gene)|ensembl:ENSMUST00000028005(transcript)|refseq:NP_079845.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:uxWRd47vtmR9RmuPoh7cfAmDgvs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9QY23	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565315|uniprotkb:A4QPD8|uniprotkb:Q0VGP3|uniprotkb:Q3KQL7|ensembl:ENSMUSP00000069961	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:pkp3_mouse(display_long)|uniprotkb:Pkp3(gene name)|psi-mi:Pkp3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001156396.1|refseq:NP_062736.2|ensembl:ENSMUSG00000054065(gene)|ensembl:ENSMUST00000066873(transcript)|go:"GO:0002159"(desmosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005914"(spot adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028434|interpro:IPR028435|reactome:R-MMU-6805567|reactome:R-MMU-6809371	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Qq/hrdQkMF4cc9QR2TtSprNLQCE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9Z1N5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-647702|uniprotkb:Q8HW97|ensembl:ENSMUSP00000070682|ensembl:ENSMUSP00000133428|ensembl:ENSMUSP00000134178	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dx39b_mouse(display_long)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:Ddx39b(gene name)|psi-mi:Ddx39b(display_short)|uniprotkb:Bat1a(gene name synonym)|uniprotkb:Uap56(gene name synonym)|uniprotkb:Bat1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_062667.1|refseq:NP_001239386.1|ensembl:ENSMUSG00000019432(gene)|ensembl:ENSMUST00000068056(transcript)|ensembl:ENSMUST00000172549(transcript)|ensembl:ENSMUST00000173731(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9Z1N5|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-9013418	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:KFD8ORH0BbsAlrCymbikAmnhPVs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9DC69	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-772731|intact:EBI-2934552|uniprotkb:Q6GTD3|uniprotkb:Q99JP9|ensembl:ENSMUSP00000144904	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndua9_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:Ndufa9(gene name)|psi-mi:Ndufa9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_079634.2|ensembl:ENSMUSG00000000399(gene)|ensembl:ENSMUST00000205002(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR008030(NmrA-like)|interpro:IPR036291|mint:Q9DC69|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:cyWl9Af7lg/hJx/mANKhMVV4jbQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P13020	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-445180|uniprotkb:Q3UPB1|uniprotkb:Q8R590|intact:EBI-4281654|ensembl:ENSMUSP00000028239	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:gels_mouse(display_long)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:Gsn(gene name)|psi-mi:Gsn(display_short)|uniprotkb:Gsb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_666232.2|ensembl:ENSMUSG00000026879(gene)|ensembl:ENSMUST00000028239(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043209"(myelin sheath)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051593"(response to folic acid)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P13020|rcsb pdb:1NPH|rcsb pdb:4CBU|rcsb pdb:4CBW|rcsb pdb:4CBX|rcsb pdb:5MVV|rcsb pdb:6I4D|rcsb pdb:6I4E|rcsb pdb:6I4F|rcsb pdb:6I4G|rcsb pdb:6I4H|rcsb pdb:6I4I|rcsb pdb:6I4J|rcsb pdb:6I4K|rcsb pdb:6I4L|rcsb pdb:6I4M|reactome:R-MMU-264870|reactome:R-MMU-6798695|dip:DIP-31941N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:vByKB6qbsPzebkkufeXoP6n0SUI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P19157	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2309446|uniprotkb:Q8BNY4|ensembl:ENSMUSP00000129565	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:gstp1_mouse(display_long)|uniprotkb:Gstp1(gene name)|psi-mi:Gstp1(display_short)|uniprotkb:Gstpib(gene name synonym)|uniprotkb:GST YF-YF(gene name synonym)|uniprotkb:GST-piB(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:Preadipocyte growth factor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_038569.1|ensembl:ENSMUSG00000060803(gene)|ensembl:ENSMUST00000169613(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:2000429"(negative regulation of neutrophil aggregation)|go:"GO:2000469"(negative regulation of peroxidase activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|mint:P19157|rcsb pdb:1BAY|rcsb pdb:1GLP|rcsb pdb:1GLQ|rcsb pdb:1GSY|rcsb pdb:1GTI|rcsb pdb:2GLR|rcsb pdb:2OA7|rcsb pdb:2OAC|rcsb pdb:2OAD|rcsb pdb:3O76|reactome:R-MMU-156590|reactome:R-MMU-3299685|reactome:R-MMU-6798695	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:hJoMh/r+TgFJqQL95dBmcBsAVn810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CRB9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299847|ensembl:ENSMUSP00000070149	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mic19_mouse(display_long)|uniprotkb:Chchd3(gene name)|psi-mi:Chchd3(display_short)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:Mic19(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000053768(gene)|ensembl:ENSMUST00000066379(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0019902"(phosphatase binding)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|mint:Q9CRB9|refseq:NP_079612.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:rxWY2UHnmX3tUiI8/TrJxthCxc010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P05202	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-444923|uniprotkb:Q3TIP6|uniprotkb:Q3UD91|uniprotkb:Q5HZH5|uniprotkb:O09188|ensembl:ENSMUSP00000034097	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:aatm_mouse(display_long)|uniprotkb:Transaminase A(gene name synonym)|uniprotkb:Glutamate oxaloacetate transaminase 2(gene name synonym)|uniprotkb:Fatty acid-binding protein(gene name synonym)|uniprotkb:Plasma membrane-associated fatty acid-binding protein(gene name synonym)|uniprotkb:Kynurenine aminotransferase 4(gene name synonym)|uniprotkb:Kynurenine aminotransferase IV(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase 4(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase IV(gene name synonym)|uniprotkb:Got2(gene name)|psi-mi:Got2(display_short)|uniprotkb:Got-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_034455.1|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0045471"(response to ethanol)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P05202|rcsb pdb:3HLM|rcsb pdb:3PD6|rcsb pdb:3PDB|reactome:R-MMU-389661|reactome:R-MMU-8963693|reactome:R-MMU-8964539|reactome:R-MMU-70263|ensembl:ENSMUST00000034097(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0009986"(cell surface)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0016597"(amino acid binding)|go:"GO:0019550"(glutamate catabolic process to aspartate)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030315"(T-tubule)|ensembl:ENSMUSG00000031672(gene)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:derWMXIiDl1XkaQdJ48VFA7HMzM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8VCM7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6252682|ensembl:ENSMUSP00000037018|uniprotkb:Q8WUR3|uniprotkb:Q91ZP0	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:fibg_mouse(display_long)|uniprotkb:Fgg(gene name)|psi-mi:Fgg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000033860(gene)|ensembl:ENSMUST00000048486(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037581|mint:Q8VCM7|reactome:R-MMU-114608|reactome:R-MMU-140875|reactome:R-MMU-216083|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-381426|reactome:R-MMU-5674135|reactome:R-MMU-5686938|reactome:R-MMU-8957275|refseq:NP_598623.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:AmOFe/GrPI4CGlyrFHBM1QHxYOk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q99MR8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773469|uniprotkb:Q3TGU0|uniprotkb:Q9D8R2|ensembl:ENSMUSP00000029259	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mcca_mouse(display_long)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym)|uniprotkb:Mccc1(gene name)|psi-mi:Mccc1(display_short)|uniprotkb:Mcca(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_076133.3|ensembl:ENSMUSG00000027709(gene)|ensembl:ENSMUST00000029259(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q99MR8|reactome:R-MMU-196780|reactome:R-MMU-70895	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:SziuYdcOx+maKy71pNxoKql1HGI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O35643	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-348937|uniprotkb:Q3TXG4|uniprotkb:Q922E2|ensembl:ENSMUSP00000009234	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ap1b1_mouse(display_long)|uniprotkb:Ap1b1(gene name)|psi-mi:Ap1b1(display_short)|uniprotkb:Adtb1(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031480.2|ensembl:ENSMUSG00000009090(gene)|ensembl:ENSMUST00000009234(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048268"(clathrin coat assembly)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:zTEB4qq5OQCyxOOnVs9OeWAQBqA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A6ZI44	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-4283485|ensembl:ENSMUSP00000084846	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a6zi44_mouse(display_long)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001170778.1|refseq:XP_006507272.1|ensembl:ENSMUSG00000030695(gene)|ensembl:ENSMUST00000087566(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006096"(glycolytic process)|go:"GO:0009408"(response to heat)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035094"(response to nicotine)|go:"GO:0043627"(response to estrogen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:QfjcGwfzA6vJ+Ip6oyWZf4ZCtQM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8C8R3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-774322|intact:EBI-2133064|uniprotkb:Q6PCN2|uniprotkb:Q3TM62|uniprotkb:Q3V2X0|uniprotkb:Q80ZZ7|uniprotkb:Q8BNC1|uniprotkb:Q8C445|uniprotkb:Q8CCV0|intact:EBI-2255612|intact:EBI-8314005|intact:MINT-4115219	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ank2_mouse(display_long)|uniprotkb:Brain ankyrin(gene name synonym)|uniprotkb:AnkB(gene name synonym)|uniprotkb:Ank2(gene name)|psi-mi:Ank2(display_short)|uniprotkb:Ankyrin-B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001029340.1|refseq:NP_848770.2|dip:DIP-58645N|mint:Q8C8R3|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0008104"(protein localization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0015031"(protein transport)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031430"(M band)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031672"(A band)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0036309"(protein localization to M-band)|go:"GO:0036371"(protein localization to T-tubule)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086014"(atrial cardiac muscle cell action potential)|go:"GO:0086015"(SA node cell action potential)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086066"(atrial cardiac muscle cell to AV node cell communication)|go:"GO:0086070"(SA node cell to atrial cardiac muscle cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901021"(positive regulation of calcium ion transmembrane transporter activity)|go:"GO:2001257"(regulation of cation channel activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR040745	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:SkB13oxZVcKuMnI8r5ItFIq2pXQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3TED3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565719	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3ted3_mouse(display_long)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym)|uniprotkb:Acly(gene name)|psi-mi:Acly(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR014608(ATP-citrate synthase)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR032263|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR036969|interpro:IPR033847|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR036291|interpro:IPR017866|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0003878"(ATP citrate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:dwGVIraTSnWfzMbY447bNThwIEc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D828	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-308969	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q9d828_mouse(display_long)|uniprotkb:Tfg(gene name)|psi-mi:Tfg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|interpro:IPR034857|interpro:IPR033512	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ROdjt7CfqfZJ3ELcZihI3jIUG5A10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQN1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-4286155|uniprotkb:Q542I4|ensembl:ENSMUSP00000006137	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:trap1_mouse(display_long)|uniprotkb:Trap1(gene name)|psi-mi:Trap1(display_short)|uniprotkb:Hsp75(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_080784.1|ensembl:ENSMUSG00000005981(gene)|ensembl:ENSMUST00000006137(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q9CQN1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:8DL4FdXZj8opXUye3mhVpcHjbdU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P14602	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299023|ensembl:ENSMUSP00000005077	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9WUB3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1371761|ensembl:ENSMUSP00000047564	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P62918	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6910319|ensembl:ENSMUSP00000004072|ensembl:ENSMUSP00000155657|uniprotkb:P25120|uniprotkb:Q3V288	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl8_mouse(display_long)|uniprotkb:Rpl8(gene name)|psi-mi:Rpl8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62918|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000003970(gene)|ensembl:ENSMUST00000004072(transcript)|ensembl:ENSMUST00000229183(transcript)|go:"GO:0002181"(cytoplasmic translation)|refseq:NP_036183.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8K3J1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934407|ensembl:ENSMUSP00000074600|ensembl:ENSMUSP00000158029|ensembl:ENSMUSP00000158327|ensembl:ENSMUSP00000158541	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndus8_mouse(display_long)|uniprotkb:Ndufs8(gene name)|psi-mi:Ndufs8(display_short)|uniprotkb:Complex I-23kD(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 23 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000059734(gene)|ensembl:ENSMUST00000075092(transcript)|ensembl:ENSMUST00000235847(transcript)|ensembl:ENSMUST00000236801(transcript)|ensembl:ENSMUST00000237341(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR010226(NADH-quinone oxidoreductase, chain I)|interpro:IPR017896|interpro:IPR017900|mint:Q8K3J1|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_659119.2|refseq:NP_001258372.1|refseq:NP_001258373.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:CMDS9FE2Nv9OeK3VGnrYqBXdwnE10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P14148	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-445010|uniprotkb:Q80UR0|ensembl:ENSMUSP00000071616	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl7_mouse(display_long)|uniprotkb:Rpl7(gene name)|psi-mi:Rpl7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035421.2|ensembl:ENSMUSG00000043716(gene)|ensembl:ENSMUST00000058437(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P14148|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:3mgKWwOhV0qZfTQwfsTkqol4iIY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9Z2Z6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-9989063|uniprotkb:Q3U801|ensembl:ENSMUSP00000035222	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mcat_mouse(display_long)|uniprotkb:Slc25a20(gene name)|psi-mi:Slc25a20(display_short)|uniprotkb:Cac(gene name synonym)|uniprotkb:Cact(gene name synonym)|uniprotkb:Carnitine/acylcarnitine translocase(gene name synonym)|uniprotkb:Solute carrier family 25 member 20(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_065266.1|interpro:IPR023395|reactome:R-MMU-200425|interpro:IPR018108|ensembl:ENSMUSG00000032602(gene)|ensembl:ENSMUST00000035222(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015227"(acyl carnitine transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902603"(carnitine transmembrane transport)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:RX+Mbe4nGGozTzodiev81QsW3JM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CZ13	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773751|uniprotkb:Q9CWL6|uniprotkb:Q3TV75|ensembl:ENSMUSP00000026743	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:qcr1_mouse(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 1(gene name synonym)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:Uqcrc1(gene name)|psi-mi:Uqcrc1(display_short)|uniprotkb:Core protein I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_079683.2|ensembl:ENSMUSG00000025651(gene)|ensembl:ENSMUST00000026743(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0014823"(response to activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:Q9CZ13|reactome:R-MMU-611105	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:oPlGhzsHLustrgdY4P+DdyJePbA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:B2RXT3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20564766|ensembl:ENSMUSP00000154185	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:b2rxt3_mouse(display_long)|uniprotkb:Ogdhl(gene name)|psi-mi:Ogdhl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001074599.1|refseq:XP_006519014.1|ensembl:ENSMUSG00000021913(gene)|ensembl:ENSMUST00000228529(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:LqIbHDr2Fb7M3okuFySeq9hQSDk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3UU58	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565714	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3uu58_mouse(display_long)|uniprotkb:Nebl(gene name)|psi-mi:Nebl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR000900(Nebulin 35 residue motif)|go:"GO:0003779"(actin binding)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:/jFa15pwH9fCHjUrCWnCj5+GAvI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q60930	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-444578|ensembl:ENSMUSP00000022293|uniprotkb:Q78MH6|uniprotkb:Q99L98	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:vdac2_mouse(display_long)|uniprotkb:Voltage-dependent anion-selective channel protein 6(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)|uniprotkb:Vdac2(gene name)|psi-mi:Vdac2(display_short)|uniprotkb:Vdac6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035825.1|ensembl:ENSMUSG00000021771(gene)|ensembl:ENSMUST00000022293(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:Q60930|reactome:R-MMU-5689880	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ApSD4TVlagQ1QHePbOZw7J5rmzQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9WUR2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2794295|uniprotkb:Q99M61|uniprotkb:Q9D785|ensembl:ENSMUSP00000131735	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:eci2_mouse(display_long)|uniprotkb:Eci2(gene name)|psi-mi:Eci2(display_short)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Peci(gene name synonym)|uniprotkb:Peroxisomal 3,2-trans-enoyl-CoA isomerase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001103801.1|refseq:NP_035998.2|refseq:XP_006516736.1|refseq:XP_006516737.1|refseq:XP_006516738.1|refseq:XP_006516739.1|refseq:XP_006516740.1|ensembl:ENSMUSG00000021417(gene)|ensembl:ENSMUST00000171229(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR001753(Crotonase, core)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR022408|interpro:IPR029045|interpro:IPR035984|mint:Q9WUR2|reactome:R-MMU-390247|reactome:R-MMU-9033241|go:"GO:0006635"(fatty acid beta-oxidation)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:nHPcS0mXXHwtPjuxHZLEOsf99sk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O35129	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-445002|uniprotkb:O89075|uniprotkb:Q61336|ensembl:ENSMUSP00000004375	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:phb2_mouse(display_long)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:Bap(gene name synonym)|uniprotkb:Bcap37(gene name synonym)|uniprotkb:Rea(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031557.2|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:O35129|reactome:R-MMU-8949664|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|ensembl:ENSMUSG00000004264(gene)|ensembl:ENSMUST00000004375(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016363"(nuclear matrix)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0016477"(cell migration)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:h4pib54mBeQgOKCe/hib58LM26w10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q99KI0	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-444886|uniprotkb:Q3UDK9|uniprotkb:Q3ULG9|uniprotkb:Q3UNH7|uniprotkb:Q505P4|ensembl:ENSMUSP00000023116	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:acon_mouse(display_long)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Aco2(gene name)|psi-mi:Aco2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_542364.1|ensembl:ENSMUSG00000022477(gene)|ensembl:ENSMUST00000023116(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0043209"(myelin sheath)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q99KI0|reactome:R-MMU-71403|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:0NOVcGhBwl4qmtnlhX9jcsQMdSo10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CPQ1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934674|ensembl:ENSMUSP00000014457|ensembl:ENSMUSP00000122391|ensembl:ENSMUSP00000123609|uniprotkb:Q52KC6	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cox6c_mouse(display_long)|uniprotkb:Cytochrome c oxidase polypeptide VIc(gene name synonym)|uniprotkb:Cox6c(gene name)|psi-mi:Cox6c(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUST00000156915(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004204(Cytochrome c oxidase subunit VIc)|interpro:IPR034884|interpro:IPR037169|mint:Q9CPQ1|ensembl:ENSMUST00000153512(transcript)|ensembl:ENSMUSG00000014313(gene)|ensembl:ENSMUST00000014457(transcript)|refseq:NP_444301.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:hOm5fzmi430bKn4GZxPSm14kr/c10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q01768	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-642573|ensembl:ENSMUSP00000021217|ensembl:ENSMUSP00000103476	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndkb_mouse(display_long)|uniprotkb:nm23-M2(gene name synonym)|uniprotkb:P18(gene name synonym)|uniprotkb:Nme2(gene name)|psi-mi:Nme2(display_short)|uniprotkb:Histidine protein kinase NDKB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001070997.1|refseq:NP_032731.1|ensembl:ENSMUSG00000020857(gene)|ensembl:ENSMUST00000021217(transcript)|ensembl:ENSMUST00000072566(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1901363"(heterocyclic compound binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:Q01768|reactome:R-MMU-499943|reactome:R-MMU-6798695	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:AJ1Depmyy9zwTEUOZMRO7TKPd1k10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P61164	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-774242|uniprotkb:P42024|uniprotkb:Q3TJF9|ensembl:ENSMUSP00000039844	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:actz_mouse(display_long)|uniprotkb:Centrosome-associated actin homolog(gene name synonym)|uniprotkb:Actin-RPV(gene name synonym)|uniprotkb:ARP1(gene name synonym)|uniprotkb:Actr1a(gene name)|psi-mi:Actr1a(display_short)|uniprotkb:Ctrn1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_058556.1|ensembl:ENSMUSG00000025228(gene)|ensembl:ENSMUST00000040270(transcript)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0043209"(myelin sheath)|go:"GO:0099738"(cell cortex region)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P61164|reactome:R-MMU-2132295|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-8854518	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:aJHKOSj1qmZ7Pk8aZAyWWd8DEdw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A8DUV1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565375	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a8duv1_mouse(display_long)|uniprotkb:Hbat1(gene name)|psi-mi:Hbat1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR000971(Globin, subset)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:qqaIfXJKAmDOpzUsRqXu8GYyldk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9R0Y5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-777466|uniprotkb:A2AK80|uniprotkb:Q542C5|uniprotkb:Q9R0Y4|ensembl:ENSMUSP00000108902|ensembl:ENSMUSP00000108903	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:kad1_mouse(display_long)|uniprotkb:ATP-AMP transphosphorylase 1(gene name synonym)|uniprotkb:Myokinase(gene name synonym)|uniprotkb:Ak1(gene name)|psi-mi:Ak1(display_short)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001185719.1|refseq:NP_001185720.1|refseq:NP_001185721.1|refseq:NP_067490.1|refseq:XP_006497687.1|ensembl:ENSMUSG00000026817(gene)|ensembl:ENSMUST00000113277(transcript)|ensembl:ENSMUST00000113278(transcript)|go:"GO:0001520"(outer dense fiber)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0030017"(sarcomere)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046103"(inosine biosynthetic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|interpro:IPR028582|interpro:IPR033690|mint:Q9R0Y5|reactome:R-MMU-499943	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:HTydMeIFNEaVZDs7sEN7aLieuVg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQA3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-432494|uniprotkb:Q3TF82|uniprotkb:Q9DC91|ensembl:ENSMUSP00000010007	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sdhb_mouse(display_long)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)|uniprotkb:Sdhb(gene name)|psi-mi:Sdhb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_075863.2|ensembl:ENSMUSG00000009863(gene)|ensembl:ENSMUST00000010007(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0045273"(respiratory chain complex II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|mint:Q9CQA3|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:867rMxM9LEdIwyu93mUmDNc1S0o10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P58281	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-776163|uniprotkb:Q3ULA5|uniprotkb:Q8BKU7|uniprotkb:Q8BLL3|uniprotkb:Q8BM08|uniprotkb:Q8R3J7|uniprotkb:A6H6Q3|ensembl:ENSMUSP00000124223	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:opa1_mouse(display_long)|uniprotkb:Optic atrophy protein 1 homolog(gene name synonym)|uniprotkb:Large GTP-binding protein(gene name synonym)|uniprotkb:Opa1(gene name)|psi-mi:Opa1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_598513.1|refseq:XP_006522720.1|ensembl:ENSMUSG00000038084(gene)|ensembl:ENSMUST00000160597(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001843"(neural tube closure)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007601"(visual perception)|go:"GO:0008017"(microtubule binding)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030425"(dendrite)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090102"(cochlea development)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090398"(cellular senescence)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904643"(response to curcumin)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR033047|mint:P58281|reactome:R-MMU-169911	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:cj1HZs8CYUuCBy4KhYmtO/lvmUk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A2AST1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565696|ensembl:ENSMUSP00000052945	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a2ast1_mouse(display_long)|uniprotkb:Ccdc141(gene name)|psi-mi:Ccdc141(display_short)|uniprotkb:CAMDI(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000044033(gene)|ensembl:ENSMUST00000049544(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0030424"(axon)|go:"GO:0051642"(centrosome localization)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018159|interpro:IPR036179|interpro:IPR043204	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:G5NjGx9ciT7nKS84gNYMv3uGdPg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A0JLR7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565679	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:a0jlr7_mouse(display_long)|uniprotkb:Ahnak(gene name)|psi-mi:Ahnak(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:3/icYBCZMk/ZhsV7USryDUvehq010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQZ6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934375|ensembl:ENSMUSP00000027193|uniprotkb:Q3UUR9	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndub3_mouse(display_long)|uniprotkb:Ndufb3(gene name)|psi-mi:Ndufb3(display_short)|uniprotkb:Complex I-B12(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B12 subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000026032(gene)|ensembl:ENSMUST00000027193(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0022900"(electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR012576(NADH-ubiquinone oxidoreductase B12 subunit)|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_079873.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:hhTBowxrL0XlFp2QYPplJGtZ11A10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BGH2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934811|ensembl:ENSMUSP00000023071|uniprotkb:Q3TIL3|uniprotkb:Q3TTG7|uniprotkb:Q3TWD3	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sam50_mouse(display_long)|uniprotkb:Samm50(gene name)|psi-mi:Samm50(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000022437(gene)|ensembl:ENSMUST00000023071(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0042407"(cristae formation)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|mint:Q8BGH2|reactome:R-MMU-9013404|refseq:NP_848729.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:OWxecVBGU7/ayT7jqSrqeKmr5fw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P80317	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-772389	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tcpz_mouse(display_long)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Cct6a(gene name)|psi-mi:Cct6a(display_short)|uniprotkb:Cct6(gene name synonym)|uniprotkb:Cctz(gene name synonym)|uniprotkb:Cctz1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033968.1|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR027409|interpro:IPR027413|interpro:IPR027410|mint:P80317|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|reactome:R-MMU-390471|reactome:R-MMU-6814122|reactome:R-MMU-9013418	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:E8vqHRMvDBqKtAu5/6UPh1mSYLw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8CI94	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773709|uniprotkb:Q8K283|ensembl:ENSMUSP00000035743	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:pygb_mouse(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_722476.1|ensembl:ENSMUSG00000033059(gene)|ensembl:ENSMUST00000045441(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q8CI94|reactome:R-MMU-6798695	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:sX820CE/XNwY/LEnJx/j4IF44Lk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D2N4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-296019|uniprotkb:P97319|uniprotkb:Q61498|uniprotkb:Q61499|uniprotkb:Q9QZZ5|uniprotkb:Q9WUL9|uniprotkb:Q9WUM0	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dtna_mouse(display_long)|uniprotkb:Dtna(gene name)|psi-mi:Dtna(display_short)|uniprotkb:Dtn(gene name synonym)|uniprotkb:Alpha-dystrobrevin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016014"(dystrobrevin complex)|refseq:NP_001272736.1|refseq:NP_001272739.1|refseq:NP_001272746.1|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|refseq:NP_034217.2|interpro:IPR017432(Distrobrevin)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR043145|refseq:XP_017173306.1|refseq:XP_017173308.1|refseq:XP_017173310.1|refseq:XP_017173311.1|refseq:XP_017173312.1|refseq:XP_017173313.1|refseq:XP_017173315.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:gqIbCFldISt+vbYeRHs3sswGPWU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P35235	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-397236|uniprotkb:Q3TQ84|uniprotkb:Q64509|uniprotkb:Q6PCL5|ensembl:ENSMUSP00000098333	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ptn11_mouse(display_long)|uniprotkb:Ptpn11(gene name)|psi-mi:Ptpn11(display_short)|uniprotkb:Protein-tyrosine phosphatase SYP(gene name synonym)|uniprotkb:SH-PTP2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001103462.1|refseq:NP_035332.1|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048659"(smooth muscle cell proliferation)|go:"GO:0048806"(genitalia development)|go:"GO:0048839"(inner ear development)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051428"(peptide hormone receptor binding)|go:"GO:0051463"(negative regulation of cortisol secretion)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0060325"(face morphogenesis)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0061582"(intestinal epithelial cell migration)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR012152(Protein-tyrosine phosphatase, non-receptor type-6, -11)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036860|mint:P35235|rcsb pdb:1AYA|rcsb pdb:1AYB|rcsb pdb:1AYC|rcsb pdb:1AYD|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|reactome:R-MMU-1059683|reactome:R-MMU-109704|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|reactome:R-MMU-110056|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|reactome:R-MMU-112411|reactome:R-MMU-114604|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR000980(SH2 motif)|reactome:R-MMU-1257604|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|reactome:R-MMU-1295596|reactome:R-MMU-1433557|reactome:R-MMU-180292|reactome:R-MMU-186763|reactome:R-MMU-210990|reactome:R-MMU-210993|reactome:R-MMU-388841|reactome:R-MMU-389513|reactome:R-MMU-389948|reactome:R-MMU-432142|reactome:R-MMU-512988|reactome:R-MMU-5654689|reactome:R-MMU-8854691|reactome:R-MMU-8865999|reactome:R-MMU-8934593|reactome:R-MMU-909733|reactome:R-MMU-912694|reactome:R-MMU-936964|reactome:R-MMU-9674555|reactome:R-MMU-5654693|reactome:R-MMU-5654695|reactome:R-MMU-5654700|reactome:R-MMU-5654706|reactome:R-MMU-5654710|reactome:R-MMU-5654712|reactome:R-MMU-5654720|reactome:R-MMU-5654726|reactome:R-MMU-5654727|reactome:R-MMU-5654732|reactome:R-MMU-5654733|reactome:R-MMU-6811558|reactome:R-MMU-8853659|ensembl:ENSMUSG00000043733(gene)|ensembl:ENSMUST00000100770(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030220"(platelet formation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032528"(microvillus organization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0033277"(abortive mitotic cell cycle)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035265"(organ growth)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043560"(insulin receptor substrate binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046825"(regulation of protein export from nucleus)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|dip:DIP-29669N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:KL26Wt9vwG525fZ5SfvLc71Wsng10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P47963	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-445016|uniprotkb:Q9CRZ9|uniprotkb:Q9DCH1|ensembl:ENSMUSP00000000756	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl13_mouse(display_long)|uniprotkb:A52(gene name synonym)|uniprotkb:Rpl13(gene name)|psi-mi:Rpl13(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_058018.2|ensembl:ENSMUSG00000000740(gene)|ensembl:ENSMUST00000000756(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0060348"(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P47963|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0022626"(cytosolic ribosome)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:s4+tKYYhhfFHM5TZCNIgbE2hQds10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3TB96	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20564754	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3tb96_mouse(display_long)|uniprotkb:Dctn1(gene name)|psi-mi:Dctn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR036859|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR022157|go:"GO:0005938"(cell cortex)|go:"GO:0030286"(dynein complex)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:W8yy2oLAjYxUGqH8mcl8niuK5iI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3TTN3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565668	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3ttn3_mouse(display_long)|uniprotkb:Vdac3(gene name)|psi-mi:Vdac3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR023614|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR027246|interpro:IPR030271|go:"GO:0000166"(nucleotide binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0046930"(pore complex)|go:"GO:1902017"(regulation of cilium assembly)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:164gb6pBr17nfh0KwgYZX5LbMBo10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P62259	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8CE68	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2925699	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q8ce68_mouse(display_long)|uniprotkb:Agl(gene name)|psi-mi:Agl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0004133"(glycogen debranching enzyme activity)|go:"GO:0004134"(4-alpha-glucanotransferase activity)|go:"GO:0004135"(amylo-alpha-1,6-glucosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009725"(response to hormone)|go:"GO:0016234"(inclusion body)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0051384"(response to glucocorticoid)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR010401(Amylo-alpha-1,6-glucosidase)|interpro:IPR032790|mint:Q8CE68	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WmWMcjBrpcN/n7iYhibsPXaiEB010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:B1B0C7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565629|ensembl:ENSMUSP00000030547	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:b1b0c7_mouse(display_long)|uniprotkb:Hspg2(gene name)|psi-mi:Hspg2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000028763(gene)|ensembl:ENSMUST00000030547(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0016020"(membrane)|interpro:IPR000034(Laminin B)|interpro:IPR000082(SEA)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR023415|interpro:IPR036055|interpro:IPR036179	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:inUH0hfv9aBpYH8RTnI2GPfVQ8c10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9Z2I8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2107688|uniprotkb:Q3T9B8|uniprotkb:Q3TJQ5|uniprotkb:Q3TK63|uniprotkb:Q66JT3|uniprotkb:Q7TMY3|uniprotkb:Q80VV1|uniprotkb:Q8K2K9|ensembl:ENSMUSP00000144827	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sucb2_mouse(display_long)|uniprotkb:Suclg2(gene name)|psi-mi:Suclg2(display_short)|uniprotkb:GTP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-G chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001313487.1|refseq:NP_035637.2|ensembl:ENSMUSG00000061838(gene)|ensembl:ENSMUST00000204224(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034722|mint:Q9Z2I8|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:V1vkzx6MwooUIe9d/A66CRAoygA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D6R2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299873|ensembl:ENSMUSP00000127526|uniprotkb:Q3UAM8|uniprotkb:Q8C8A1|uniprotkb:Q9D1L1	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:idh3a_mouse(display_long)|uniprotkb:Idh3a(gene name)|psi-mi:Idh3a(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000032279(gene)|ensembl:ENSMUST00000167866(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q9D6R2|reactome:R-MMU-71403|refseq:NP_083849.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:JkEkbIT34WQdoOiBYA9kAao2lC010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:A2ASS6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-9672947|uniprotkb:A2ASS5|uniprotkb:A2ASS7	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:titin_mouse(display_long)|uniprotkb:Ttn(gene name)|psi-mi:Ttn(display_short)|uniprotkb:Connectin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR040849|rcsb pdb:6YJ0|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR004168(PPAK motif)|interpro:IPR000719(Protein kinase, core)|interpro:IPR015129(Titin Z)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR036116|interpro:IPR036179|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0002020"(protease binding)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021591"(ventricular system development)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043056"(forward locomotion)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055002"(striated muscle cell development)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060419"(heart growth)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:xDsiEoYt/F9ZCvYym/wgnXdwYbU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P61982	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-359843|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q4FK44|uniprotkb:Q3UFD6|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSMUSP00000051223|ensembl:ENSMUSP00000143631	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:1433g_mouse(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_061359.2|ensembl:ENSMUSG00000051391(gene)|ensembl:ENSMUST00000055808(transcript)|ensembl:ENSMUST00000198270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61982|reactome:R-MMU-111447|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-9614399	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3ULD5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6877475|ensembl:ENSMUSP00000022148|uniprotkb:Q3UPS6	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mccb_mouse(display_long)|uniprotkb:Mccc2(gene name)|psi-mi:Mccc2(display_short)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000021646(gene)|ensembl:ENSMUST00000022148(transcript)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q3ULD5|reactome:R-MMU-196780|reactome:R-MMU-70895|refseq:NP_084302.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:0q4wsAWb+zqTRNjZnCPoNabUrbA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9EQP2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-491022|ensembl:ENSMUSP00000028755	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ehd4_mouse(display_long)|uniprotkb:Ehd4(gene name)|psi-mi:Ehd4(display_short)|uniprotkb:Past2(gene name synonym)|uniprotkb:PAST homolog 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_598599.2|ensembl:ENSMUSG00000027293(gene)|ensembl:ENSMUST00000028755(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|interpro:IPR031692|interpro:IPR040990|mint:Q9EQP2|rcsb pdb:5MTV|rcsb pdb:5MVF|interpro:IPR030381|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Amxin/3NzINpV4SP1xvRjstQAG010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P16125	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-444932|uniprotkb:Q545Y4|ensembl:ENSMUSP00000032373|ensembl:ENSMUSP00000159362	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ldhb_mouse(display_long)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Ldhb(gene name)|psi-mi:Ldhb(display_short)|uniprotkb:Ldh-2(gene name synonym)|uniprotkb:Ldh2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032518.1|refseq:NP_001303251.1|ensembl:ENSMUSG00000030246(gene)|ensembl:ENSMUST00000032373(transcript)|ensembl:ENSMUST00000239397(transcript)|go:"GO:0004457"(lactate dehydrogenase activity)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0051287"(NAD binding)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P16125|reactome:R-MMU-70268|interpro:IPR001557(L-lactate/malate dehydrogenase)|refseq:NP_001289694.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:jN0wT7b/jHBnWCfV48irZYeGxa410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P61014	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-10148373|uniprotkb:P20006|uniprotkb:Q3UQ75|ensembl:ENSMUSP00000045709|ensembl:ENSMUSP00000132743|ensembl:ENSMUSP00000151641|ensembl:ENSMUSP00000151745|ensembl:ENSMUSP00000151860|ensembl:ENSMUSP00000151966	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ppla_mouse(display_long)|uniprotkb:Pln(gene name)|psi-mi:Pln(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001135399.1|refseq:NP_075618.1|ensembl:ENSMUST00000046221(transcript)|ensembl:ENSMUST00000163319(transcript)|ensembl:ENSMUST00000218468(transcript)|ensembl:ENSMUST00000219491(transcript)|ensembl:ENSMUST00000219921(transcript)|ensembl:ENSMUST00000220197(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008016"(regulation of heart contraction)|ensembl:ENSMUSG00000038583(gene)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033574"(response to testosterone)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086023"(adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:1901077"(regulation of relaxation of muscle)|go:"GO:1901877"(negative regulation of calcium ion binding)|go:"GO:1901895"(negative regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902081"(negative regulation of calcium ion import into sarcoplasmic reticulum)|interpro:IPR005984(Phospholamban)|rcsb pdb:3O7L|reactome:R-MMU-5578775|reactome:R-MMU-936837	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:/rJRfpGBnSyV37L7wJcTtmVsrRc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQ62	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299499|ensembl:ENSMUSP00000029877|uniprotkb:Q9DCI7	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:decr_mouse(display_long)|uniprotkb:Decr1(gene name)|psi-mi:Decr1(display_short)|uniprotkb:2,4-dienoyl-CoA reductase [NADPH](gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000028223(gene)|ensembl:ENSMUST00000029877(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008670"("2,4-dienoyl-CoA reductase (NADPH) activity")|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902494"(catalytic complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q9CQ62|reactome:R-MMU-77288|go:"GO:0042802"(identical protein binding)|go:"GO:0070402"(NADPH binding)|refseq:NP_080448.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Bh2PIoAhcHP1Sek3ELKceJj2xF410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:B9EHT6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565611|ensembl:ENSMUSP00000140816	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:b9eht6_mouse(display_long)|uniprotkb:Fn1(gene name)|psi-mi:Fn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001263340.1|ensembl:ENSMUSG00000026193(gene)|ensembl:ENSMUST00000190780(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0006953"(acute-phase response)|go:"GO:0007155"(cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0008360"(regulation of cell shape)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:o2OnvAismyV172aTjauEuHdA3Gw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q99LC3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-772722|uniprotkb:Q3UKK0|uniprotkb:Q8BL57|uniprotkb:Q9CW21|ensembl:ENSMUSP00000027478	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nduaa_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Complex I-42kD(gene name synonym)|uniprotkb:Ndufa10(gene name)|psi-mi:Ndufa10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_077159.1|ensembl:ENSMUSG00000026260(gene)|ensembl:ENSMUST00000027478(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|mint:Q99LC3|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:PnMgq3QghxkpZvkzvgjuJUqkIqY10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CXZ1	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934359|uniprotkb:Q9WUB1	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndus4_mouse(display_long)|uniprotkb:Ndufs4(gene name)|psi-mi:Ndufs4(display_short)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR038532|reactome:R-MMU-6799198|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003016"(respiratory system process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006954"(inflammatory response)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030534"(adult behavior)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050890"(cognition)|go:"GO:0051591"(response to cAMP)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070997"(neuron death)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0072593"(reactive oxygen species metabolic process)|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|go:"GO:0014876"(response to injury involved in regulation of muscle adaptation)|refseq:NP_035017.2|interpro:IPR006885(ETC complex I subunit conserved region)|mint:Q9CXZ1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:SbIn9Wz6DH4mipMhdL9qf55OJBo10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q6P8J7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565591|ensembl:ENSMUSP00000022122	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:kcrs_mouse(display_long)|uniprotkb:Basic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:Sarcomeric mitochondrial creatine kinase(gene name synonym)|uniprotkb:Ckmt2(gene name)|psi-mi:Ckmt2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_940807.1|ensembl:ENSMUSG00000021622(gene)|ensembl:ENSMUST00000022122(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006603"(phosphocreatine metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:1901612"(cardiolipin binding)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:Q6P8J7|reactome:R-MMU-71288	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:WiCiHk8tlPTl97O2Pj1PBFf3Ifs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQ75	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2255517|uniprotkb:Q9WUB2|ensembl:ENSMUSP00000014438	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndua2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym)|uniprotkb:Ndufa2(gene name)|psi-mi:Ndufa2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035015.2|ensembl:ENSMUSG00000014294(gene)|ensembl:ENSMUST00000014438(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|mint:Q9CQ75|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Z2rI9xDggf8OO321yyMsskocTYM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9D6J6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-444755|uniprotkb:Q3U9L9|uniprotkb:Q8BU07|uniprotkb:Q8K2L0|ensembl:ENSMUSP00000121557	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nduv2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:Ndufv2(gene name)|psi-mi:Ndufv2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_082664.1|ensembl:ENSMUSG00000024099(gene)|ensembl:ENSMUST00000143987(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0043209"(myelin sheath)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:Q9D6J6|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_001265344.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:vM53PN+rw08xEYT9/DP4ljGSN2g10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q62417	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2365368|uniprotkb:Q80TF8|uniprotkb:Q8BZI3|uniprotkb:Q8K3Y2|uniprotkb:Q921F8|uniprotkb:Q9Z0Z8|uniprotkb:Q9Z0Z9	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:srbs1_mouse(display_long)|uniprotkb:Sorbs1(gene name)|psi-mi:Sorbs1(display_short)|uniprotkb:Kiaa1296(gene name synonym)|uniprotkb:Sh3d5(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001030134.1|refseq:NP_001030135.1|refseq:NP_001030136.1|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q62417|go:"GO:0001725"(stress fiber)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|reactome:R-MMU-445355	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:3+0ZfSkNB+9ujOF3uyXmP2ovl8A10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQH3	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934537|ensembl:ENSMUSP00000114963	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndub5_mouse(display_long)|uniprotkb:Ndufb5(gene name)|psi-mi:Ndufb5(display_short)|uniprotkb:Complex I-SGDH(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase SGDH subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000027673(gene)|ensembl:ENSMUST00000127477(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019173|mint:Q9CQH3|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|rcsb pdb:6ZTQ|refseq:NP_079592.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:4uKYAyCAmfXZr34JQcuTyjoVhA810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O55126	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-775353	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nips2_mouse(display_long)|uniprotkb:Nipsnap2(gene name)|psi-mi:Nipsnap2(display_short)|uniprotkb:Gbas(gene name synonym)|uniprotkb:Glioblastoma-amplified sequence(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:O55126|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|reactome:R-MMU-9013407	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:3/7ucu45We86PZTIrYjVKab5hYs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8BKZ9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6877565|ensembl:ENSMUSP00000011058	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:odpx_mouse(display_long)|uniprotkb:Pdhx(gene name)|psi-mi:Pdhx(display_short)|uniprotkb:Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Lipoyl-containing pyruvate dehydrogenase complex component X(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000010914(gene)|ensembl:ENSMUST00000011058(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:Q8BKZ9|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268|refseq:NP_780303.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:5b1n89M4YLpENMk4kqCsO2oQqJ010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9JKS4	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299323|ensembl:ENSMUSP00000022327|uniprotkb:Q6A038|uniprotkb:Q811P2|uniprotkb:Q811P3|uniprotkb:Q811P4|uniprotkb:Q811P5|uniprotkb:Q9D130|uniprotkb:Q9JKS3|uniprotkb:Q9R0Z1|uniprotkb:Q9WVH1|uniprotkb:Q9WVH2|uniprotkb:B2RSB0|uniprotkb:B7ZNT6	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ldb3_mouse(display_long)|uniprotkb:Ldb3(gene name)|psi-mi:Ldb3(display_short)|uniprotkb:Z-band alternatively spliced PDZ-motif protein(gene name synonym)|uniprotkb:Protein cypher(gene name synonym)|uniprotkb:Protein oracle(gene name synonym)|uniprotkb:Kiaa0613(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000021798(gene)|ensembl:ENSMUST00000022327(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031143"(pseudopodium)|go:"GO:0031941"(filamentous actin)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|mint:Q9JKS4|rcsb pdb:1WJL|refseq:NP_001034160.1|refseq:NP_001034161.1|refseq:NP_001034162.1|refseq:NP_001034163.1|refseq:NP_001034164.1|refseq:NP_001034165.1|refseq:NP_036048.3|refseq:XP_006519080.1|refseq:XP_017171508.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:cw40AYt3wGbDuNniByp+mt33HjQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:B2RY15	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565561	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:b2ry15_mouse(display_long)|uniprotkb:Tln2(gene name)|psi-mi:Tln2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR036723|interpro:IPR019749|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR035963|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR032425|interpro:IPR035964|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037438|interpro:IPR015224(Talin, central)|interpro:IPR036476|interpro:IPR029071|interpro:IPR015009(Vinculin Binding Site)|go:"GO:0001726"(ruffle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0051015"(actin filament binding)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Esp5Hfyy1UiOLnREi/y4xixf9lk10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O70373	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565540	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:xirp1_mouse(display_long)|uniprotkb:Cardiomyopathy-associated protein 1(gene name synonym)|uniprotkb:Xirp1(gene name)|psi-mi:Xirp1(display_short)|uniprotkb:Cmya1(gene name synonym)|uniprotkb:Xin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR012510(Actin Binding Sixteen Amino Acid)|interpro:IPR030072|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014704"(intercalated disc)|go:"GO:0031005"(filamin binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|go:"GO:0055013"(cardiac muscle cell development)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:230wASitwuGF203BnX1Qd3Az1mc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P27546	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2526714|uniprotkb:Q05BJ2|uniprotkb:Q3UIS2|uniprotkb:Q3UUH5|uniprotkb:Q3UY36|uniprotkb:Q7TPC6|uniprotkb:Q7TPD4|uniprotkb:Q80YQ5|uniprotkb:Q8CFP5|ensembl:ENSMUSP00000035055	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:map4_mouse(display_long)|uniprotkb:Map4(gene name)|psi-mi:Map4(display_short)|uniprotkb:Mtap4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001192259.1|refseq:NP_001192261.1|refseq:NP_032659.2|ensembl:ENSMUSG00000032479(gene)|ensembl:ENSMUST00000035055(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27546|go:"GO:0043005"(neuron projection)|refseq:NP_001298092.1|refseq:NP_001298093.1|refseq:XP_017168653.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:DVblnhNfUaxX6rpvxn660Pq09L410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CWK0	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-4286270	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q9cwk0_mouse(display_long)|uniprotkb:Rpl14(gene name)|psi-mi:Rpl14(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR002784(Ribosomal protein L14)|interpro:IPR014722(Translation protein SH3-like, subgroup)|mint:Q9CWK0|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR039660|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR041985	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:7cOC2RFf58l9cMSA2Y4a4UjQ4hg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8K0E8	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1634324|uniprotkb:Q91ZP1|ensembl:ENSMUSP00000039472	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:fibb_mouse(display_long)|uniprotkb:Fgb(gene name)|psi-mi:Fgb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_862897.1|ensembl:ENSMUSG00000033831(gene)|ensembl:ENSMUST00000048246(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:Q8K0E8|reactome:R-MMU-114608|reactome:R-MMU-140875|reactome:R-MMU-216083|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|reactome:R-MMU-5686938	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:bEenetOknasilOE63oJ+BAi+PlI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P03888	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934268|ensembl:ENSMUSP00000080991|uniprotkb:Q9G0S6	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nu1m_mouse(display_long)|uniprotkb:Mtnd1(gene name)|psi-mi:Mtnd1(display_short)|uniprotkb:mt-Nd1(gene name synonym)|uniprotkb:Nd1(gene name synonym)|uniprotkb:NADH dehydrogenase subunit 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000064341(gene)|ensembl:ENSMUST00000082392(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|go:"GO:0005747"(mitochondrial respiratory chain complex I)|rcsb pdb:7AK5|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|rcsb pdb:7AK6|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|rcsb pdb:7B93|go:"GO:0009060"(aerobic respiration)|go:"GO:0030425"(dendrite)|reactome:R-MMU-611105|reactome:R-MMU-6799198|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0043025"(neuronal cell body)|interpro:IPR001694(Respiratory-chain NADH dehydrogenase, subunit 1)|interpro:IPR018086|rcsb pdb:6G2J|refseq:NP_904328.1|dip:DIP-61655N|refseq:YP_220550.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:SjMJxcFumymfyBPEXpxDC6Sq6V410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CZU6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773122|uniprotkb:Q3UDP3|ensembl:ENSMUSP00000005826	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cisy_mouse(display_long)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym)|uniprotkb:Cs(gene name)|psi-mi:Cs(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_080720.1|ensembl:ENSMUSG00000005683(gene)|ensembl:ENSMUST00000005826(transcript)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0046912"(acyltransferase, acyl groups converted into alkyl on transfer)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|mint:Q9CZU6|rcsb pdb:3NZI|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:0Ct6UHozD3vl5QxB0YOeKsSEUQw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P47738	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2308120|ensembl:ENSMUSP00000031411	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:aldh2_mouse(display_long)|uniprotkb:Aldh2(gene name)|psi-mi:Aldh2(display_short)|uniprotkb:Ahd-1(gene name synonym)|uniprotkb:Ahd1(gene name synonym)|uniprotkb:ALDH class 2(gene name synonym)|uniprotkb:AHD-M1(gene name synonym)|uniprotkb:ALDHI(gene name synonym)|uniprotkb:ALDH-E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033786.1|ensembl:ENSMUSG00000029455(gene)|ensembl:ENSMUST00000031411(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051287"(NAD binding)|go:"GO:0070404"(NADH binding)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P47738|reactome:R-MMU-380612|reactome:R-MMU-71384	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:C4L2qigIlQeaZH4RsNocJovkPMw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:B7ZCI2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20564738|ensembl:ENSMUSP00000117805	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:b7zci2_mouse(display_long)|uniprotkb:Nebl(gene name)|psi-mi:Nebl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000053702(gene)|ensembl:ENSMUST00000124270(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030018"(Z disc)|go:"GO:0031005"(filamin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0071691"(cardiac muscle thin filament assembly)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035631|interpro:IPR036028	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:+fiQSUMncpvsYK0M9GVSnPbO1nU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q91YT0	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934319|ensembl:ENSMUSP00000042967	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nduv1_mouse(display_long)|uniprotkb:Ndufv1(gene name)|psi-mi:Ndufv1(display_short)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000037916(gene)|ensembl:ENSMUST00000042497(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:Q91YT0|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_598427.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:xYJ5XxA1aRAaXMrlI8U+e9owOPU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P17710	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773368|uniprotkb:E9PXQ3|uniprotkb:Q61659|uniprotkb:Q64476|uniprotkb:Q64479	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:hxk1_mouse(display_long)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Hexokinase, tumor isozyme(gene name synonym)|uniprotkb:Hk1(gene name)|psi-mi:Hk1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR001312(Hexokinase)|interpro:IPR022673|interpro:IPR019807|interpro:IPR022672|refseq:XP_006513305.1|refseq:XP_006513306.1|refseq:XP_006513307.1|refseq:XP_006513308.1|interpro:IPR043129|mint:P17710|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008865"(fructokinase activity)|go:"GO:0010359"(regulation of anion channel activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0047931"(glucosamine kinase activity)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|reactome:R-MMU-70171	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:x4T9LnTLPxq69q+uvfTwLT8gCn410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P09671	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1635071|uniprotkb:Q8VEM5|uniprotkb:Q64670|ensembl:ENSMUSP00000007012	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:sodm_mouse(display_long)|uniprotkb:Sod2(gene name)|psi-mi:Sod2(display_short)|uniprotkb:Sod-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_038699.2|ensembl:ENSMUSG00000006818(gene)|ensembl:ENSMUST00000007012(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000303"(response to superoxide)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001889"(liver development)|go:"GO:0003032"(detection of oxygen)|go:"GO:0003069"(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0003677"(DNA binding)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007507"(heart development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014823"(response to activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0035900"(response to isolation stress)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048666"(neuron development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048773"(erythrophore differentiation)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071000"(response to magnetism)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902631"(negative regulation of membrane hyperpolarization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905932"(positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019831|interpro:IPR019832|interpro:IPR019833|interpro:IPR036314|interpro:IPR036324|mint:P09671|reactome:R-MMU-2151201|reactome:R-MMU-3299685	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ElUPIiA1JSb5vbfqnibv3He227E10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P07310	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-299493|ensembl:ENSMUSP00000146972	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:kcrm_mouse(display_long)|uniprotkb:Ckm(gene name)|psi-mi:Ckm(display_short)|uniprotkb:Ckmm(gene name synonym)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000030399(gene)|ensembl:ENSMUST00000208710(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006603"(phosphocreatine metabolic process)|go:"GO:0009408"(response to heat)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P07310|reactome:R-MMU-71288|refseq:NP_031736.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:HUwtOLpKEeqrxa326Rz+yjZ6/Mo10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O08532	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-770939|uniprotkb:O08533|uniprotkb:O08534|uniprotkb:O08535|uniprotkb:O08536|ensembl:ENSMUSP00000049457	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ca2d1_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha-2/delta-1(gene name synonym)|uniprotkb:Cacna2d1(gene name)|psi-mi:Cacna2d1(display_short)|uniprotkb:Cacna2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001104313.1|refseq:NP_001104314.1|refseq:NP_001104315.1|refseq:NP_001104316.1|refseq:NP_033914.1|ensembl:ENSMUSG00000040118(gene)|ensembl:ENSMUST00000039370(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030315"(T-tubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086057"(voltage-gated calcium channel activity involved in bundle of His cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013608(VWA N-terminal)|interpro:IPR013680(Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region)|interpro:IPR036465|mint:O08532	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:fY8StGDMVTfTBrs3lV7rYVrjvBg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q6PHZ2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2308458|uniprotkb:Q3UF87|uniprotkb:Q3UQH9|uniprotkb:Q5DTK4|uniprotkb:Q8CAC5|uniprotkb:Q9CZE2|ensembl:ENSMUSP00000143504	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:kcc2d_mouse(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001020609.1|refseq:NP_076302.1|refseq:NP_001020610.1|refseq:NP_001280592.1|refseq:NP_001280593.1|dip:DIP-47638N|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000199300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q6PHZ2|rcsb pdb:6BAB|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q80X90	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-688023|intact:EBI-777273|uniprotkb:E9QNV9|uniprotkb:Q8VHX4|uniprotkb:Q8VHX7|uniprotkb:Q99KY3|ensembl:ENSMUSP00000052020	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:flnb_mouse(display_long)|uniprotkb:Flnb(gene name)|psi-mi:Flnb(display_short)|uniprotkb:ABP-280-like protein(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001074896.1|ensembl:ENSMUSG00000025278(gene)|ensembl:ENSMUST00000052678(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:Q80X90|reactome:R-MMU-1169408|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:A5bnyO/GwzIgn56NbxZGMkAWYk410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P19253	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-445023|ensembl:ENSMUSP00000115722	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl13a_mouse(display_long)|uniprotkb:Transplantation antigen P198(gene name synonym)|uniprotkb:Tum-P198 antigen(gene name synonym)|uniprotkb:Rpl13a(gene name)|psi-mi:Rpl13a(display_short)|uniprotkb:P198(gene name synonym)|uniprotkb:Tstap198-7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033464.2|ensembl:ENSMUSG00000074129(gene)|ensembl:ENSMUST00000150350(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042592"(homeostatic process)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1901194"(negative regulation of formation of translation preinitiation complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005755(Ribosomal protein L13, eukaryotic/archaeal)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR023563|interpro:IPR036899|mint:P19253|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|rcsb pdb:6SWA	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:OHHQbay1m62ZSGYnKANekTh+C5Q10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q791V5	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-775885|ensembl:ENSMUSP00000121851|uniprotkb:Q3TPS5|uniprotkb:Q99LZ6|uniprotkb:Q9D060|uniprotkb:Q9D7Y2|uniprotkb:Q9QZP3	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:mtch2_mouse(display_long)|uniprotkb:Mtch2(gene name)|psi-mi:Mtch2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0071478"(cellular response to radiation)|go:"GO:0090152"(establishment of protein localization to mitochondrial membrane involved in mitochondrial fission)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|ensembl:ENSMUSG00000027282(gene)|ensembl:ENSMUST00000136872(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|interpro:IPR018108|interpro:IPR023395|mint:Q791V5|refseq:NP_062732.1|refseq:NP_001304170.1|refseq:NP_001304171.1|refseq:NP_001304172.1|refseq:NP_001304173.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:5TT13uYcx21wiKjuQc4tynZ31Ac10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P63101	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-354751|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q3TSF1|uniprotkb:Q5EBQ1|ensembl:ENSMUSP00000022894|ensembl:ENSMUSP00000105990|ensembl:ENSMUSP00000105991	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:1433z_mouse(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:SEZ-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001240734.1|refseq:NP_001240735.1|refseq:NP_035870.1|refseq:XP_011243654.1|ensembl:ENSMUSG00000022285(gene)|ensembl:ENSMUST00000110361(transcript)|ensembl:ENSMUST00000110362(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|ensembl:ENSMUST00000022894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63101|reactome:R-MMU-111447|reactome:R-MMU-3769402|reactome:R-MMU-392517|reactome:R-MMU-430116|reactome:R-MMU-450604|reactome:R-MMU-512988|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9013700|reactome:R-MMU-9614399|dip:DIP-31894N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q7TQI9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565534	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q7tqi9_mouse(display_long)|uniprotkb:Lama2(gene name)|psi-mi:Lama2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR001791(Laminin G)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:k4Fbymfa9c60st1IdJetjPiGOyw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q08284	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20564643	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q08284_mouse(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR021996|go:"GO:0007596"(blood coagulation)|interpro:IPR037579	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:kU9SIvw8LtejHyKpN2cXStuUFXU10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9DCS9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934580|ensembl:ENSMUSP00000043543|uniprotkb:Q3UAE3	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nduba_mouse(display_long)|uniprotkb:Ndufb10(gene name)|psi-mi:Ndufb10(display_short)|uniprotkb:Complex I-PDSW(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase PDSW subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000040048(gene)|ensembl:ENSMUST00000045602(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR019377|interpro:IPR039993|mint:Q9DCS9|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|go:"GO:0005739"(mitochondrion)|refseq:NP_080960.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:9nKm586YEKm1ZCA7DvpcCK2xNLg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3USI2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565523	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3usi2_mouse(display_long)|uniprotkb:Lamb2(gene name)|psi-mi:Lamb2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_032509.2|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR013015(Laminin IV)|interpro:IPR008211(Laminin, N-terminal)|go:"GO:0005604"(basement membrane)|go:"GO:0016020"(membrane)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:xwTlnBHTmmBQ+iVuXa8WSO/RPrA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:O08749	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773199|uniprotkb:Q3TG55|uniprotkb:Q3U5W5|uniprotkb:Q3UWP7|uniprotkb:Q99LD3|ensembl:ENSMUSP00000106481	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:dldh_mouse(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Dld(gene name)|psi-mi:Dld(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_031887.2|ensembl:ENSMUSG00000020664(gene)|ensembl:ENSMUST00000110857(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043209"(myelin sheath)|go:"GO:0043544"(lipoamide binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:O08749|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-6783984|reactome:R-MMU-70268|reactome:R-MMU-70895|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:6j/8rw4lkNMW4Lo5sGoRdDJBk2w10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q3U0Q9	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565507	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q3u0q9_mouse(display_long)|uniprotkb:Tns1(gene name)|psi-mi:Tns1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|interpro:IPR035012|interpro:IPR033929|go:"GO:0003779"(actin binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030055"(cell-substrate junction)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:lSlgLxhfMcppE0tQSv/Wk7xG5nQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q1XH17	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-16034016|ensembl:ENSMUSP00000079832|ensembl:ENSMUSP00000101855|uniprotkb:B2RWH7|uniprotkb:Q6NX76	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tri72_mouse(display_long)|uniprotkb:Trim72(gene name)|psi-mi:Trim72(display_short)|uniprotkb:Mg53(gene name synonym)|uniprotkb:Mitsugumin-53(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000042828(gene)|ensembl:ENSMUST00000081042(transcript)|ensembl:ENSMUST00000106248(transcript)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003012"(muscle system process)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043569"(negative regulation of insulin-like growth factor receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR035038|interpro:IPR043136|reactome:R-MMU-445355|refseq:NP_001073401.1|refseq:XP_006508065.1|dip:DIP-60129N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:ThT0W0/SAuu4DZqJddiPNcF6yLA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P00405	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-773506|uniprotkb:Q85K21|ensembl:ENSMUSP00000080994	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cox2_mouse(display_long)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:Mtco2(gene name)|psi-mi:Mtco2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:mt-Co2(gene name synonym)|uniprotkb:COX2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_904331.1|ensembl:ENSMUSG00000064354(gene)|ensembl:ENSMUST00000082405(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00405|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:oM1rnc+HJvDAF3+Z9fgK35b0UIw10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CQC7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2255646|ensembl:ENSMUSP00000023514	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ndub4_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym)|uniprotkb:Ndufb4(gene name)|psi-mi:Ndufb4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_080886.1|refseq:XP_001476621.1|refseq:XP_001478493.1|ensembl:ENSMUSG00000022820(gene)|ensembl:ENSMUST00000023514(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|mint:Q9CQC7|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:bOgcV3wmpY11CMgEaMUGzcugRiM10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P14206	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8CC88	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-12602574|ensembl:ENSMUSP00000048925|uniprotkb:Q3U4P9|uniprotkb:Q6ZQ94|uniprotkb:Q8CDH8|uniprotkb:Q8VCU3	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:vwa8_mouse(display_long)|uniprotkb:Vwa8(gene name)|psi-mi:Vwa8(display_short)|uniprotkb:Kiaa0564(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000058997(gene)|ensembl:ENSMUST00000040990(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|mint:Q8CC88|refseq:NP_082182.1|refseq:NP_776119.2	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:JRlZvEqyEowI+W/4vQZy0mZEQk810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P10493	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1032117|uniprotkb:Q8BQI3|uniprotkb:Q8C3U8|uniprotkb:Q8C9P6|uniprotkb:Q3TKX9|ensembl:ENSMUSP00000005532	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nid1_mouse(display_long)|uniprotkb:Nid1(gene name)|psi-mi:Nid1(display_short)|uniprotkb:Ent(gene name synonym)|uniprotkb:Entactin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_035047.2|interpro:IPR026823|interpro:IPR036857|mint:P10493|rcsb pdb:1GL4|rcsb pdb:1H4U|rcsb pdb:1NPE|reactome:R-MMU-1474228|reactome:R-MMU-3000157|ensembl:ENSMUSG00000005397(gene)|ensembl:ENSMUST00000005532(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071944"(cell periphery)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:3dnqHnqAO3PlU6v5pchyqrF4UBg10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P70670	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-647147|uniprotkb:E9QMB1|ensembl:ENSMUSP00000089680	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nacam_mouse(display_long)|uniprotkb:Gm1878(gene name synonym)|uniprotkb:Alpha-NAC, muscle-specific form(gene name synonym)|uniprotkb:Naca(gene name)|psi-mi:Naca(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001106670.1|refseq:NP_038636.2|ensembl:ENSMUSG00000061315(gene)|ensembl:ENSMUST00000092048(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051451"(myoblast migration)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:P70670	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:4QZh6JIwWgCTyZyvNxj5mmR6Bps10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q01853	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-80597|ensembl:ENSMUSP00000030164|uniprotkb:Q3TFH9|uniprotkb:Q3TIM2|uniprotkb:Q3TXN9|uniprotkb:Q6PI18|uniprotkb:Q8BSR6|uniprotkb:Q8CEG4	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:tera_mouse(display_long)|uniprotkb:Vcp(gene name)|psi-mi:Vcp(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:Q01853|rcsb pdb:1E32|rcsb pdb:1R7R|rcsb pdb:1S3S|rcsb pdb:2PJH|rcsb pdb:3CF0|rcsb pdb:3CF1|rcsb pdb:3CF2|rcsb pdb:3CF3|reactome:R-MMU-110320|reactome:R-MMU-3371511|reactome:R-MMU-382556|reactome:R-MMU-532668|reactome:R-MMU-5358346|reactome:R-MMU-5689877|reactome:R-MMU-5689896|reactome:R-MMU-6798695|reactome:R-MMU-8876725|reactome:R-MMU-9013407|ensembl:ENSMUSG00000028452(gene)|ensembl:ENSMUST00000030164(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0019904"(protein domain specific binding)|refseq:NP_033529.3|dip:DIP-29796N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9ERS2	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2934630|ensembl:ENSMUSP00000105796|uniprotkb:Q9DC98|uniprotkb:Q9DCA1	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:nduad_mouse(display_long)|uniprotkb:Ndufa13(gene name)|psi-mi:Ndufa13(display_short)|uniprotkb:Grim19(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000036199(gene)|ensembl:ENSMUST00000110167(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9ERS2|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_075801.1|refseq:XP_017168432.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:wgq95IYdQM3hRpOywBXA0Axqil010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P62889	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-4285659|uniprotkb:P04645|ensembl:ENSMUSP00000009039|ensembl:ENSMUSP00000106014	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:rl30_mouse(display_long)|uniprotkb:Rpl30(gene name)|psi-mi:Rpl30(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001156957.1|refseq:NP_033109.1|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035368"(selenocysteine insertion sequence binding)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62889|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000058600(gene)|ensembl:ENSMUST00000009039(transcript)|ensembl:ENSMUST00000079735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0014069"(postsynaptic density)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:xR9LwYg6N7m9njT1pYumOPKZVu410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q9CR68	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1219616|uniprotkb:Q5SVV1|ensembl:ENSMUSP00000045284	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:ucri_mouse(display_long)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:Uqcrfs1(gene name)|psi-mi:Uqcrfs1(display_short)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_079986.1|mint:Q9CR68|reactome:R-MMU-611105|ensembl:ENSMUSG00000038462(gene)|ensembl:ENSMUST00000042834(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:nlXLFf9AMJ4fhZUsdE8cVraBuW410090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q05504	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20564682	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q05504_mouse(display_long)|uniprotkb:Col6a3(gene name)|psi-mi:Col6a3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042383"(sarcolemma)|go:"GO:0062023"(collagen-containing extracellular matrix)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:bGfhWrmwdQEoDqhkRyYkMvL0Q9810090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q64727	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-432047|uniprotkb:Q8BP32|uniprotkb:Q8BS46|uniprotkb:Q922C5|uniprotkb:Q922D9|ensembl:ENSMUSP00000022369	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:vinc_mouse(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:Vcl(gene name)|psi-mi:Vcl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_033528.3|ensembl:ENSMUSG00000021823(gene)|ensembl:ENSMUST00000022369(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042383"(sarcolemma)|go:"GO:0043297"(apical junction assembly)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0048675"(axon extension)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:Q64727|rcsb pdb:5Y04|reactome:R-MMU-114608|reactome:R-MMU-445355|reactome:R-MMU-5674135|reactome:R-MMU-6798695	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:bfHsrHTLESS6CIctYpg0yX3N+UA10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q5SXR6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-2308526|ensembl:ENSMUSP00000050220	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q5sxr6_mouse(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000047126(gene)|ensembl:ENSMUST00000060766(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:zQkMlHHZuHQwJ3cU5pWAx/f6guc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q8VHX6	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-400843|uniprotkb:Q6PAI6|uniprotkb:B2RY80|uniprotkb:B9EKT2|uniprotkb:Q9JJ38|ensembl:ENSMUSP00000064163	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:flnc_mouse(display_long)|uniprotkb:Flnc(gene name)|psi-mi:Flnc(display_short)|uniprotkb:Abpl(gene name synonym)|uniprotkb:Fln2(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:NP_001074654.1|refseq:NP_001298003.1|ensembl:ENSMUSG00000068699(gene)|mint:Q8VHX6|ensembl:ENSMUST00000065090(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-MMU-446353	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:xohwAtNkerMr1ZBB5Pi8QLYPo0Y10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:Q810I7	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-20565498	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:q810i7_mouse(display_long)|uniprotkb:Apoa4(gene name)|psi-mi:Apoa4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	interpro:IPR000074(Apolipoprotein A1/A4/E)|go:"GO:0006869"(lipid transport)|go:"GO:0008289"(lipid binding)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0042157"(lipoprotein metabolic process)	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:jFR8cXVZS43POWkvTcgsRM6Wapc10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P02469	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-6662997|ensembl:ENSMUSP00000002979|ensembl:ENSMUSP00000132778|uniprotkb:E9PXZ9	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:lamb1_mouse(display_long)|uniprotkb:Lamb1(gene name)|psi-mi:Lamb1(display_short)|uniprotkb:Lamb-1(gene name synonym)|uniprotkb:Lamb1-1(gene name synonym)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	refseq:XP_006515055.2|ensembl:ENSMUSG00000002900(gene)|ensembl:ENSMUST00000002979(transcript)|ensembl:ENSMUST00000169088(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0007611"(learning or memory)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042476"(odontogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8874081|go:"GO:0070831"(basement membrane assembly)|reactome:R-MMU-8957275|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P02469|rcsb pdb:4AQS|rcsb pdb:5MC9|refseq:XP_006515056.1	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:cUuVqY2JMeRrS9sDYudPy7hSIL010090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P51637	uniprotkb:P49817	intact:EBI-298576|ensembl:ENSMUSP00000074922	intact:EBI-1161338|uniprotkb:Q8C1X7|uniprotkb:Q8CBP4|uniprotkb:Q9QYH3|uniprotkb:Q9QYH4|ensembl:ENSMUSP00000007799|ensembl:ENSMUSP00000111116	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:cav1_mouse(display_long)|uniprotkb:Cav1(gene name)|psi-mi:Cav1(display_short)|uniprotkb:Cav(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20565496|imex:IM-26422-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	ensembl:ENSMUSG00000007655(gene)|ensembl:ENSMUST00000007799(transcript)|ensembl:ENSMUST00000115456(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0042060"(wound healing)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0052547"(regulation of peptidase activity)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070836"(caveola assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090398"(cellular senescence)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001258"(negative regulation of cation channel activity)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|interpro:IPR018361|mint:P49817|reactome:R-MMU-203615|reactome:R-MMU-203641|reactome:R-MMU-210991|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|reactome:R-MMU-4641262|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|reactome:R-MMU-9696273|reactome:R-MMU-9696264|refseq:NP_001229993.1|refseq:NP_031642.1|refseq:XP_006505037.1|refseq:XP_006505038.1|refseq:XP_006505039.1|dip:DIP-35140N	-	-	-	figure legend:Table S6, Fig. S4|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2020/10/22	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rogid:63vvAW/JPjuk8ZV3ZqoYdsy4umQ10090	rigid:O9jNcxvMPf4AzEGY2kxkygvMjeg	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P11499	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-492813|uniprotkb:O89078|uniprotkb:Q3UIQ7|ensembl:ENSMUSP00000024739	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:hs90b_mouse(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Tumor-specific transplantation 84 kDa antigen(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hsp84-1(gene name synonym)|uniprotkb:Hspcb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_032328.2|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P11499|reactome:R-MMU-168928|reactome:R-MMU-2029482|reactome:R-MMU-3371497|reactome:R-MMU-3371511|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-399954|reactome:R-MMU-6798695|reactome:R-MMU-844456|reactome:R-MMU-8852276|reactome:R-MMU-8937144|reactome:R-MMU-8939211|reactome:R-MMU-9013418|reactome:R-MMU-9018519|ensembl:ENSMUSG00000023944(gene)|ensembl:ENSMUST00000024739(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|dip:DIP-461N	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:5/MXDESVXdwuWna0s87Ap19aLMA10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q6PB66	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1371262|uniprotkb:Q8K4V0|uniprotkb:Q9CRX4|ensembl:ENSMUSP00000107927	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:lpprc_mouse(display_long)|uniprotkb:Lrpprc(gene name)|psi-mi:Lrpprc(display_short)|uniprotkb:Lrp130(gene name synonym)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_082509.2|ensembl:ENSMUSG00000024120(gene)|ensembl:ENSMUST00000112308(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|reactome:R-MMU-611105|reactome:R-MMU-9707564|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:Q6PB66|reactome:R-MMU-5628897|go:"GO:0005634"(nucleus)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:wNo59nF0OqIHfnoUrxN10z7YIGM10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P61358	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8401481|intact:MINT-1863099|ensembl:ENSMUSP00000090305|ensembl:ENSMUSP00000102870	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:rl27_mouse(display_long)|uniprotkb:Rpl27(gene name)|psi-mi:Rpl27(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_035419.1|refseq:XP_017170385.1|ensembl:ENSMUSG00000063316(gene)|ensembl:ENSMUST00000077856(transcript)|ensembl:ENSMUST00000107249(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61358|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	comment:mint	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P34914	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8321134|intact:MINT-1859181|uniprotkb:Q8CGV0|ensembl:ENSMUSP00000069209	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:hyes_mouse(display_long)|uniprotkb:Ephx2(gene name)|psi-mi:Ephx2(display_short)|uniprotkb:Eph2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001258332.1|refseq:NP_031966.2|ensembl:ENSMUSG00000022040(gene)|ensembl:ENSMUST00000070515(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002539"(prostaglandin production involved in inflammatory response)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0033885"("10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity")|go:"GO:0042577"(lipid phosphatase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0046272"(stilbene catabolic process)|go:"GO:0046839"(phospholipid dephosphorylation)|go:"GO:0052642"(lysophosphatidic acid phosphatase activity)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0097176"(epoxide metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR006439(HAD-superfamily hydrolase, subfamily IA, variant 1)|interpro:IPR023198|interpro:IPR023214|interpro:IPR029058|interpro:IPR036412|interpro:IPR041492|mint:P34914|rcsb pdb:1CQZ|rcsb pdb:1CR6|rcsb pdb:1EK1|rcsb pdb:1EK2|reactome:R-MMU-2142670|reactome:R-MMU-9018682|reactome:R-MMU-9033241	-	-	function:"Acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. Has phosphatase activity"|comment:mint	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:jK9/K11NHaeX7vX0aK77T/hbYlU10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q99LC5	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8334254|uniprotkb:Q8BMD3|intact:MINT-1859759|uniprotkb:Q4V9X5|uniprotkb:Q3THD7|uniprotkb:Q8BMU7|uniprotkb:Q3V000|ensembl:ENSMUSP00000034866	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:etfa_mouse(display_long)|uniprotkb:Etfa(gene name)|psi-mi:Etfa(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_663590.3|ensembl:ENSMUSG00000032314(gene)|ensembl:ENSMUST00000034866(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017133"(mitochondrial electron transfer flavoprotein complex)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR001308(Electron transfer flavoprotein, alpha subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR014731(Electron transfer flavoprotein, alpha subunit, C-terminal)|interpro:IPR018206|interpro:IPR029035|interpro:IPR033947|mint:Q99LC5|reactome:R-MMU-611105	-	-	comment:mint|function:"The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)"	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:J1V6KKCCnRXkfr72ArCLeyh9FLg10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q99NB1	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8346875|intact:MINT-4086737|uniprotkb:Q8K0M6|ensembl:ENSMUSP00000028944	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:acs2l_mouse(display_long)|uniprotkb:Acss1(gene name)|psi-mi:Acss1(display_short)|uniprotkb:Acas2(gene name synonym)|uniprotkb:Acas2l(gene name synonym)|uniprotkb:Acetate--CoA ligase 2(gene name synonym)|uniprotkb:Acetyl-CoA synthetase 2(gene name synonym)|uniprotkb:Acyl-CoA synthetase short-chain family member 1(gene name synonym)|uniprotkb:Propionate--CoA ligase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_542142.1|dip:DIP-61209N|ensembl:ENSMUSG00000027452(gene)|ensembl:ENSMUST00000028944(transcript)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0019413"(acetate biosynthetic process)|go:"GO:0019427"(acetyl-CoA biosynthetic process from acetate)|go:"GO:0019542"(propionate biosynthetic process)|go:"GO:0050218"(propionate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011904(Acetate--CoA ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR032387|interpro:IPR042099|mint:Q99NB1|reactome:R-MMU-71384	-	-	function:"Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2)"|comment:mint	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:h3dcddwI6x6n1h9/eQAdHaNuIMA10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P02468	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-7059830|intact:MINT-1031545	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:lamc1_mouse(display_long)|uniprotkb:Lamc1(gene name)|psi-mi:Lamc1(display_short)|uniprotkb:Lamb-2(gene name synonym)|uniprotkb:Lamc-1(gene name synonym)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	mint:P02468|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|rcsb pdb:1KLO|rcsb pdb:1NPE|rcsb pdb:1TLE|rcsb pdb:4AQT|rcsb pdb:5MC9|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8874081|dip:DIP-41793N	-	-	comment:mint|function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:LTc4oIJUjQ8INjkodiPpXvL/rx010090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q02788	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8344999|uniprotkb:Q05505|uniprotkb:Q8K229|uniprotkb:Q8C972|intact:MINT-4381294|ensembl:ENSMUSP00000001181	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:co6a2_mouse(display_long)|uniprotkb:Col6a2(gene name)|psi-mi:Col6a2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001334136.1|refseq:NP_666119.1|ensembl:ENSMUSG00000020241(gene)|ensembl:ENSMUST00000001181(transcript)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0009749"(response to glucose)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036465|mint:Q02788|reactome:R-MMU-1442490|reactome:R-MMU-1650814|reactome:R-MMU-186797|reactome:R-MMU-2022090|reactome:R-MMU-216083|reactome:R-MMU-3000178|reactome:R-MMU-419037|reactome:R-MMU-8948216	-	-	comment:mint|function:Collagen VI acts as a cell-binding protein	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:Hos3zhgwneI4J8IyHoLA8msT8PA10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q61425	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8334772|uniprotkb:Q925U9|uniprotkb:Q3UFI0|uniprotkb:Q8K149|uniprotkb:Q3THK8|intact:MINT-1859897|uniprotkb:Q3TF75|ensembl:ENSMUSP00000029610	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:hcdh_mouse(display_long)|uniprotkb:Mschad(gene name synonym)|uniprotkb:Schad(gene name synonym)|uniprotkb:Hadh(gene name)|psi-mi:Hadh(display_short)|uniprotkb:Hadhsc(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_032238.2|ensembl:ENSMUSG00000027984(gene)|ensembl:ENSMUST00000029610(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q61425|reactome:R-MMU-77310|reactome:R-MMU-77346|reactome:R-MMU-77348|reactome:R-MMU-77350|reactome:R-MMU-77352	-	-	function:Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA|comment:mint	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:5WS+ia58ttrPB/tirUQTBt3I0xw10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q3UTJ2	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8345744|uniprotkb:Q80TS1|intact:MINT-1853612|uniprotkb:Q3USC6|uniprotkb:Q8BX47|uniprotkb:Q8CHU0|uniprotkb:Q8BLW9|intact:MINT-4116161|uniprotkb:Q8BJL6|uniprotkb:Q8BJU3	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:srbs2_mouse(display_long)|uniprotkb:Sorbs2(gene name)|psi-mi:Sorbs2(display_short)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Argbp2(gene name synonym)|uniprotkb:Kiaa0777(gene name synonym)|uniprotkb:Arg-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001297636.1|interpro:IPR003127(Sorbin-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028506|interpro:IPR036028|mint:Q3UTJ2|refseq:XP_006509449.1|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|interpro:IPR001452(Src homology-3)	-	-	comment:"fragmentation type: fragment"	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:2sKDQux/2IV7mW8l6LK36D3qlqw10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P04247	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8312622|ensembl:ENSMUSP00000019037|ensembl:ENSMUSP00000125995|ensembl:ENSMUSP00000128399|ensembl:ENSMUSP00000155115|intact:MINT-4102659	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:myg_mouse(display_long)|uniprotkb:Mb(gene name)|psi-mi:Mb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000018893(gene)|ensembl:ENSMUST00000019037(transcript)|ensembl:ENSMUST00000166179(transcript)|ensembl:ENSMUST00000169226(transcript)|ensembl:ENSMUST00000229423(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0009725"(response to hormone)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031444"(slow-twitch skeletal muscle fiber contraction)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050873"(brown fat cell differentiation)|interpro:IPR000971(Globin, subset)|interpro:IPR002335(Myoglobin)|interpro:IPR009050(Globin-like)|mint:P04247|reactome:R-MMU-8981607|go:"GO:0007507"(heart development)|refseq:NP_001157520.1|refseq:NP_038621.2|refseq:NP_001157519.1	-	-	function:Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles|comment:mint	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:t8d0m/glCqCdeTFXQ1rvC8QtukU10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:O88492	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8347295|uniprotkb:Q69Z80|uniprotkb:E9QN72|intact:MINT-4105562|uniprotkb:Q8BNV5|ensembl:ENSMUSP00000002908|ensembl:ENSMUSP00000139859	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:plin4_mouse(display_long)|uniprotkb:Kiaa1881(gene name synonym)|uniprotkb:Adipocyte protein S3-12(gene name synonym)|uniprotkb:Plin4(gene name)|psi-mi:Plin4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_065593.2|ensembl:ENSMUSG00000002831(gene)|ensembl:ENSMUST00000002908(transcript)|ensembl:ENSMUST00000190703(transcript)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR004279(Perilipin)|mint:O88492	-	-	comment:mint|function:May play a role in triacylglycerol packaging into adipocytes. May function as a coat protein involved in the biogenesis of lipid droplets	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:VIrsWg+3qqLWYOcp+l6NNgXcG2M10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9QYG0	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8319326|uniprotkb:Q3TI48|uniprotkb:Q3TY42|uniprotkb:Q3U3T5|uniprotkb:Q69ZN2|uniprotkb:Q8C661|intact:MINT-1854707|ensembl:ENSMUSP00000004673	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:ndrg2_mouse(display_long)|uniprotkb:Ndrg2(gene name)|psi-mi:Ndrg2(display_short)|uniprotkb:Ndr2(gene name synonym)|uniprotkb:Kiaa1248(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 2 protein(gene name synonym)|uniprotkb:Protein Ndr2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:XP_006519161.2|refseq:XP_006519162.2|refseq:NP_038892.1|refseq:NP_001139431.1|refseq:XP_006519166.1|refseq:XP_006519167.1|refseq:XP_006519168.1|refseq:XP_017171534.1|refseq:XP_017171535.1|refseq:XP_017171536.1|refseq:XP_017171538.1|refseq:XP_017171539.1|refseq:XP_017171540.1|ensembl:ENSMUSG00000004558(gene)|ensembl:ENSMUST00000004673(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010574"(regulation of vascular endothelial growth factor production)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090361"(regulation of platelet-derived growth factor production)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030690|mint:Q9QYG0|rcsb pdb:2QMQ	-	-	function:May be involved in dendritic cell and neuron differentiation|comment:mint	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:gjnqnwthmc6Q2ZeVGRMbifbjy6k10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P51174	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8345212|uniprotkb:O35302|uniprotkb:Q9CU29|uniprotkb:Q9DB83|uniprotkb:B2KGC6|intact:MINT-1861818|uniprotkb:Q8QZR6	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:acadl_mouse(display_long)|uniprotkb:Acadl(gene name)|psi-mi:Acadl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|refseq:NP_031407.2|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR034179|interpro:IPR036250|interpro:IPR037069|mint:P51174|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009062"(fatty acid catabolic process)|go:"GO:0009409"(response to cold)|go:"GO:0016401"(palmitoyl-CoA oxidase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042413"(carnitine catabolic process)|go:"GO:0042758"(long-chain fatty acid catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0046322"(negative regulation of fatty acid oxidation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|reactome:R-MMU-77285|reactome:R-MMU-77310|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)	-	-	comment:mint	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:AhEJczI8Mvr0mAx2w1u+QFZ+fWA10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P45952	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8344397|uniprotkb:Q64235|intact:MINT-1860219|ensembl:ENSMUSP00000072483	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:acadm_mouse(display_long)|uniprotkb:Acadm(gene name)|psi-mi:Acadm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_031408.1|ensembl:ENSMUSG00000062908(gene)|ensembl:ENSMUST00000072697(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001889"(liver development)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007507"(heart development)|go:"GO:0009409"(response to cold)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016853"(isomerase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0030424"(axon)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|mint:P45952|reactome:R-MMU-77288|reactome:R-MMU-77346|reactome:R-MMU-77348	-	-	function:This enzyme is specific for acyl chain lengths of 4 to 16|comment:mint	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:Zfgo1s6CGy4mfJ3L1T7CHc6vQd810090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q04857	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8345547|intact:MINT-4091372|ensembl:ENSMUSP00000001147	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:co6a1_mouse(display_long)|uniprotkb:Col6a1(gene name)|psi-mi:Col6a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_034063.1|ensembl:ENSMUSG00000001119(gene)|ensembl:ENSMUST00000001147(transcript)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042383"(sarcolemma)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR036465|mint:Q04857|reactome:R-MMU-1442490|reactome:R-MMU-1650814|reactome:R-MMU-186797|reactome:R-MMU-2022090|reactome:R-MMU-216083|reactome:R-MMU-3000178|reactome:R-MMU-419037|reactome:R-MMU-8948216	-	-	comment:mint|function:Collagen VI acts as a cell-binding protein	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:kM8Xi8xfLOEcDb2NpFlknxpak8U10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q62234	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8344887|intact:UNK-5482362|uniprotkb:Q6PAC0|intact:MINT-4102904|uniprotkb:Q546T8|ensembl:ENSMUSP00000072945	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:myom1_mouse(display_long)|uniprotkb:Myom1(gene name)|psi-mi:Myom1(display_short)|uniprotkb:Myomesin family member 1(gene name synonym)|uniprotkb:Skelemin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_034997.2|refseq:NP_001077403.1|ensembl:ENSMUSG00000024049(gene)|ensembl:ENSMUST00000073211(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:Q62234|rcsb pdb:2JTD|rcsb pdb:4V10	-	-	comment:mint|function:May link the intermediate filament cytoskeleton to the M-disc of the myofibrils in striated muscle. May also contact myosin filaments. Also binds beta-integrins	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:sfJeAhoFhpjW9v1ci8pVYx2k30410090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:O70468	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	-	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P15508	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8312472|intact:MINT-1867611	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:sptb1_mouse(display_long)|uniprotkb:Sptb(gene name)|psi-mi:Sptb(display_short)|uniprotkb:Spnb1(gene name synonym)|uniprotkb:Spnb-1(gene name synonym)|uniprotkb:Sptb1(gene name synonym)|uniprotkb:Beta-I spectrin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:0051015"(actin filament binding)|go:"GO:0051693"(actin filament capping)|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|go:"GO:0032991"(protein-containing complex)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0009986"(cell surface)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030863"(cortical cytoskeleton)|interpro:IPR018159|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR036872|mint:P15508|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)	-	-	comment:mint|function:Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:z4EphKJwcEvoChbzc2oiLhL+nCw10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P08032	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-8350116|uniprotkb:B2RWX6|intact:MINT-85326|uniprotkb:P97502|ensembl:ENSMUSP00000027817	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:spta1_mouse(display_long)|uniprotkb:Spta1(gene name)|psi-mi:Spta1(display_short)|uniprotkb:Spna1(gene name synonym)|uniprotkb:Spta(gene name synonym)|uniprotkb:Erythroid alpha-spectrin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_035595.2|ensembl:ENSMUSG00000026532(gene)|ensembl:ENSMUST00000027817(transcript)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036028|mint:P08032|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878	-	-	comment:mint|function:Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:uaswmTQnd1d+MrnYyCICUC3vTkM10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q8BTM8	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-641991|uniprotkb:B7FAV0|uniprotkb:O54934|uniprotkb:Q7TQI1|uniprotkb:Q8BLK1|uniprotkb:Q8BTN7|uniprotkb:Q8VHX5|uniprotkb:Q8VHX8|uniprotkb:Q99KQ2|ensembl:ENSMUSP00000033699	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:flna_mouse(display_long)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:Flna(gene name)|psi-mi:Flna(display_short)|uniprotkb:Fln(gene name synonym)|uniprotkb:Fln1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:XP_006527974.1|ensembl:ENSMUST00000033699(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|ensembl:ENSMUSG00000031328(gene)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0097368"(establishment of Sertoli cell barrier)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q8BTM8|reactome:R-MMU-114608|reactome:R-MMU-430116|reactome:R-MMU-446353|reactome:R-MMU-5627123	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:hp3whHs7nFMTtChpQ/KywkPalq810090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P11531	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9DCW4	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1634288|uniprotkb:Q810V3|ensembl:ENSMUSP00000004729	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:etfb_mouse(display_long)|uniprotkb:Etfb(gene name)|psi-mi:Etfb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_080971.2|ensembl:ENSMUSG00000004610(gene)|ensembl:ENSMUST00000004729(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0009055"(electron transfer activity)|go:"GO:0017133"(mitochondrial electron transfer flavoprotein complex)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|interpro:IPR000049(Electron transfer flavoprotein, beta-subunit, core)|interpro:IPR012255(Electron transfer flavoprotein, beta subunit)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR014730(Electron transfer flavoprotein, alpha/beta-subunit, N-terminal)|interpro:IPR033948|mint:Q9DCW4|reactome:R-MMU-611105|reactome:R-MMU-8876725	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:eCcG+jkuQlxw/TzcOkzCBoAKJ8Y10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P42125	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20565816|uniprotkb:Q8QZV3|ensembl:ENSMUSP00000157291	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:eci1_mouse(display_long)|uniprotkb:3,2-trans-enoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),Delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym)|uniprotkb:Eci1(gene name)|psi-mi:Eci1(display_short)|uniprotkb:Dci(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_034153.2|ensembl:ENSMUSG00000024132(gene)|ensembl:ENSMUST00000234304(transcript)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|go:"GO:0042802"(identical protein binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|interpro:IPR029045|reactome:R-MMU-77288	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:WQfWjTwgG5wX4lIQFsCerDiJD9s10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q8BWT1	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1634016|uniprotkb:Q8JZR8|intact:EBI-4285676|uniprotkb:Q3TIT9|ensembl:ENSMUSP00000037348	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:thim_mouse(display_long)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acaa2(gene name)|psi-mi:Acaa2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_803421.1|ensembl:ENSMUSG00000036880(gene)|ensembl:ENSMUST00000041053(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q8BWT1|reactome:R-MMU-77289	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:15aWO97WJBNGYD449bAgjVjkgTY10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q91WD5	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-772751|uniprotkb:Q3U5Y9|uniprotkb:Q3UJX7|uniprotkb:Q99L23|uniprotkb:Q3TNA8|ensembl:ENSMUSP00000013737	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:ndus2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)|uniprotkb:Ndufs2(gene name)|psi-mi:Ndufs2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_694704.1|ensembl:ENSMUSG00000013593(gene)|ensembl:ENSMUST00000013737(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:Q91WD5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:dk8e26C1hIdTZvDnX5nE1n+juwk10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q60597	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-773541|uniprotkb:Q3UDM7|uniprotkb:Q5DTI4|uniprotkb:Q5SVX7|uniprotkb:Q5SVX9|uniprotkb:Q6PFZ2|uniprotkb:Q80Y57|uniprotkb:Q8K0K7|uniprotkb:Q8K2Z3|uniprotkb:Q8R3M2|uniprotkb:Q91WP2|ensembl:ENSMUSP00000003461|ensembl:ENSMUSP00000099090	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:odo1_mouse(display_long)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:Ogdh(gene name)|psi-mi:Ogdh(display_short)|uniprotkb:Kiaa4192(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_035086.2|refseq:XP_006514645.1|refseq:XP_006514646.1|refseq:XP_006514647.1|refseq:XP_006514648.1|refseq:NP_001239211.1|refseq:NP_001239212.1|refseq:NP_001239216.1|refseq:NP_001239217.1|refseq:XP_017169826.1|ensembl:ENSMUSG00000020456(gene)|ensembl:ENSMUST00000003461(transcript)|ensembl:ENSMUST00000101554(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q60597|rcsb pdb:3E2H|rcsb pdb:3TF7|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:6as/Sp5FTXpjU1BwjR7vJ6xcxuA10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q920E8	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20566418	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:q920e8_mouse(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:moxHRplmV6CdO4mXZzXWvG661/810090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q62417	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-2365368|uniprotkb:Q80TF8|uniprotkb:Q8BZI3|uniprotkb:Q8K3Y2|uniprotkb:Q921F8|uniprotkb:Q9Z0Z8|uniprotkb:Q9Z0Z9	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:srbs1_mouse(display_long)|uniprotkb:Sorbs1(gene name)|psi-mi:Sorbs1(display_short)|uniprotkb:Kiaa1296(gene name synonym)|uniprotkb:Sh3d5(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001030134.1|refseq:NP_001030135.1|refseq:NP_001030136.1|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q62417|go:"GO:0001725"(stress fiber)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005899"(insulin receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016600"(flotillin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|reactome:R-MMU-445355	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:3+0ZfSkNB+9ujOF3uyXmP2ovl8A10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q8K0E8	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1634324|uniprotkb:Q91ZP1|ensembl:ENSMUSP00000039472	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:fibb_mouse(display_long)|uniprotkb:Fgb(gene name)|psi-mi:Fgb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_862897.1|ensembl:ENSMUSG00000033831(gene)|ensembl:ENSMUST00000048246(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:Q8K0E8|reactome:R-MMU-114608|reactome:R-MMU-140875|reactome:R-MMU-216083|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|reactome:R-MMU-5686938	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:bEenetOknasilOE63oJ+BAi+PlI10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:A8DUK7	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20565746	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:a8duk7_mouse(display_long)|uniprotkb:Hbbt1(gene name)|psi-mi:Hbbt1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR000971(Globin, subset)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR002337(Haemoglobin, beta)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:cJXu91/136+2tk/Q+bu7ytZwKwA10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P48678	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-299212|ensembl:ENSMUSP00000029699|uniprotkb:P11516|uniprotkb:P97859|uniprotkb:Q3TIH0|uniprotkb:Q3TTS8|uniprotkb:Q3UCA0|uniprotkb:Q3UCJ8|uniprotkb:Q91WF2|uniprotkb:Q9DC21|uniprotkb:B3RH23|uniprotkb:B3RH24|uniprotkb:Q3U733|uniprotkb:Q3U7I5|uniprotkb:Q3UCU3	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:lmna_mouse(display_long)|uniprotkb:Lmna(gene name)|psi-mi:Lmna(display_short)|uniprotkb:Lmn1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|ensembl:ENSMUSG00000028063(gene)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|ensembl:ENSMUST00000029699(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1904178"(negative regulation of adipose tissue development)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P48678|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|rcsb pdb:1UFG|reactome:R-MMU-352238|reactome:R-MMU-4419969|refseq:NP_001002011.2|refseq:NP_001104572.1|refseq:NP_062263.1|refseq:XP_006501136.1|dip:DIP-31384N	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:bJz9o/dZoD9E4CRP1FLYihybpwA10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P50462	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-299294|ensembl:ENSMUSP00000032658|ensembl:ENSMUSP00000129378	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:csrp3_mouse(display_long)|uniprotkb:Csrp3(gene name)|psi-mi:Csrp3(display_short)|uniprotkb:Clp(gene name synonym)|uniprotkb:Mlp(gene name synonym)|uniprotkb:LIM domain protein, cardiac(gene name synonym)|uniprotkb:Muscle LIM protein(gene name synonym)|uniprotkb:Cysteine-rich protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:0031433"(telethonin binding)|go:"GO:0033292"(T-tubule organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043426"(MRF binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060537"(muscle tissue development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903920"(positive regulation of actin filament severing)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P50462|ensembl:ENSMUSG00000030470(gene)|ensembl:ENSMUST00000032658(transcript)|ensembl:ENSMUST00000167786(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007507"(heart development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|refseq:NP_001185770.1|refseq:NP_038836.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:EbPKIwE6y1DIHlksFKgyAulACW810090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9R0Y5	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-777466|uniprotkb:A2AK80|uniprotkb:Q542C5|uniprotkb:Q9R0Y4|ensembl:ENSMUSP00000108902|ensembl:ENSMUSP00000108903	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:kad1_mouse(display_long)|uniprotkb:ATP-AMP transphosphorylase 1(gene name synonym)|uniprotkb:Myokinase(gene name synonym)|uniprotkb:Ak1(gene name)|psi-mi:Ak1(display_short)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001185719.1|refseq:NP_001185720.1|refseq:NP_001185721.1|refseq:NP_067490.1|refseq:XP_006497687.1|ensembl:ENSMUSG00000026817(gene)|ensembl:ENSMUST00000113277(transcript)|ensembl:ENSMUST00000113278(transcript)|go:"GO:0001520"(outer dense fiber)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0030017"(sarcomere)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046103"(inosine biosynthetic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|interpro:IPR028582|interpro:IPR033690|mint:Q9R0Y5|reactome:R-MMU-499943	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:HTydMeIFNEaVZDs7sEN7aLieuVg10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:A0T1J8	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20565836	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:a0t1j8_mouse(display_long)|uniprotkb:Lmo7(gene name)|psi-mi:Lmo7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_963287.2|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR031865|interpro:IPR029978|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR003096(SM22/calponin)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0023051"(regulation of signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0042805"(actinin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:5bDREaTK+HDQYiunktDRtc3E3Mc10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q01768	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-642573|ensembl:ENSMUSP00000021217|ensembl:ENSMUSP00000103476	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:ndkb_mouse(display_long)|uniprotkb:nm23-M2(gene name synonym)|uniprotkb:P18(gene name synonym)|uniprotkb:Nme2(gene name)|psi-mi:Nme2(display_short)|uniprotkb:Histidine protein kinase NDKB(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001070997.1|refseq:NP_032731.1|ensembl:ENSMUSG00000020857(gene)|ensembl:ENSMUST00000021217(transcript)|ensembl:ENSMUST00000072566(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1901363"(heterocyclic compound binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:Q01768|reactome:R-MMU-499943|reactome:R-MMU-6798695	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:AJ1Depmyy9zwTEUOZMRO7TKPd1k10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P52480	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-647785|uniprotkb:Q3TBV8|uniprotkb:Q3TBW5|uniprotkb:Q3TC59|uniprotkb:Q3U1X3|uniprotkb:Q3U5P6|uniprotkb:Q4VC20|uniprotkb:Q64484|uniprotkb:Q91YI8|uniprotkb:Q9CWB1|ensembl:ENSMUSP00000034834	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:kpym_mouse(display_long)|uniprotkb:Pkm(gene name)|psi-mi:Pkm(display_short)|uniprotkb:Pk3(gene name synonym)|uniprotkb:Pkm2(gene name synonym)|uniprotkb:Pykm(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_035229.2|refseq:XP_006510918.1|refseq:NP_001240812.1|refseq:XP_011240975.1|dip:DIP-40536N|ensembl:ENSMUSG00000032294(gene)|ensembl:ENSMUST00000034834(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001889"(liver development)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042866"(pyruvate biosynthetic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043531"(ADP binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1902912"(pyruvate kinase complex)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P52480|reactome:R-MMU-6798695|reactome:R-MMU-70171	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:SWQx3aPATcnlExhyy8afjcrB+xo10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P20152	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid://GDvGAXOR4hUXNtVpnZefex5v410090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q8CC88	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-12602574|ensembl:ENSMUSP00000048925|uniprotkb:Q3U4P9|uniprotkb:Q6ZQ94|uniprotkb:Q8CDH8|uniprotkb:Q8VCU3	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:vwa8_mouse(display_long)|uniprotkb:Vwa8(gene name)|psi-mi:Vwa8(display_short)|uniprotkb:Kiaa0564(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000058997(gene)|ensembl:ENSMUST00000040990(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|mint:Q8CC88|refseq:NP_082182.1|refseq:NP_776119.2	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:JRlZvEqyEowI+W/4vQZy0mZEQk810090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P14733	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-445247|uniprotkb:Q61791|ensembl:ENSMUSP00000025486	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:lmnb1_mouse(display_long)|uniprotkb:Lmnb1(gene name)|psi-mi:Lmnb1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_034851.2|mint:P14733|reactome:R-MMU-9035034|reactome:R-MMU-2559584|reactome:R-MMU-352238|reactome:R-MMU-4419969|reactome:R-MMU-9013405|ensembl:ENSMUSG00000024590(gene)|ensembl:ENSMUST00000025486(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:1904609"(cellular response to monosodium L-glutamate)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|go:"GO:0003690"(double-stranded DNA binding)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:/Mo4KS6v6KhDRlYgD5CVVVtWVD810090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q6PHZ2	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-2308458|uniprotkb:Q3UF87|uniprotkb:Q3UQH9|uniprotkb:Q5DTK4|uniprotkb:Q8CAC5|uniprotkb:Q9CZE2|ensembl:ENSMUSP00000143504	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:kcc2d_mouse(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001020609.1|refseq:NP_076302.1|refseq:NP_001020610.1|refseq:NP_001280592.1|refseq:NP_001280593.1|dip:DIP-47638N|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000199300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q6PHZ2|rcsb pdb:6BAB|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9Z1N5	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-647702|uniprotkb:Q8HW97|ensembl:ENSMUSP00000070682|ensembl:ENSMUSP00000133428|ensembl:ENSMUSP00000134178	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:dx39b_mouse(display_long)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:Ddx39b(gene name)|psi-mi:Ddx39b(display_short)|uniprotkb:Bat1a(gene name synonym)|uniprotkb:Uap56(gene name synonym)|uniprotkb:Bat1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_062667.1|refseq:NP_001239386.1|ensembl:ENSMUSG00000019432(gene)|ensembl:ENSMUST00000068056(transcript)|ensembl:ENSMUST00000172549(transcript)|ensembl:ENSMUST00000173731(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9Z1N5|reactome:R-MMU-159236|reactome:R-MMU-72187|reactome:R-MMU-73856|reactome:R-MMU-9013418	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:KFD8ORH0BbsAlrCymbikAmnhPVs10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:O08709	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:O88342	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-6914976|ensembl:ENSMUSP00000005234	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:wdr1_mouse(display_long)|uniprotkb:Wdr1(gene name)|psi-mi:Wdr1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:1990266"(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|reactome:R-MMU-114608|ensembl:ENSMUSG00000005103(gene)|ensembl:ENSMUST00000005234(transcript)|go:"GO:0002102"(podosome)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0040011"(locomotion)|go:"GO:0042247"(establishment of planar polarity of follicular epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043297"(apical junction assembly)|refseq:NP_035845.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:PVIlQDv8eXQrI3QBWJOjKlj/Zig10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P12970	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-773955|uniprotkb:Q91YM3|ensembl:ENSMUSP00000099962	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:rl7a_mouse(display_long)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:Rpl7a(gene name)|psi-mi:Rpl7a(display_short)|uniprotkb:Surf3(gene name synonym)|uniprotkb:Surf-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_038749.1|ensembl:ENSMUSG00000062647(gene)|ensembl:ENSMUST00000102898(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P12970|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:XRP8YT3AaHxiv41NmJygfWNtBEs10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9DCT2	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-772758|uniprotkb:Q8BTZ3|uniprotkb:Q8R073|ensembl:ENSMUSP00000005647	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:ndus3_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym)|uniprotkb:Ndufs3(gene name)|psi-mi:Ndufs3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_080964.1|dip:DIP-32378N|ensembl:ENSMUSG00000005510(gene)|ensembl:ENSMUST00000005647(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016604"(nuclear body)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:Q9DCT2|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|reactome:R-MMU-9013408	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:2tQasToTy6/l6HeQwM+hTVH2Mow10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P17879	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-397360|uniprotkb:Q61689|uniprotkb:Q925V6|ensembl:ENSMUSP00000133815	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:hs71b_mouse(display_long)|uniprotkb:Hspa1b(gene name)|psi-mi:Hspa1b(display_short)|uniprotkb:Hcp70.1(gene name synonym)|uniprotkb:Hsp70-1(gene name synonym)|uniprotkb:Hsp70a1(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:Hspa1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_034608.2|dip:DIP-31549N|ensembl:ENSMUSG00000090877(gene)|ensembl:ENSMUST00000172753(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009408"(response to heat)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|mint:P17879|reactome:R-MMU-3371453|go:"GO:0005739"(mitochondrion)|reactome:R-MMU-3371497|reactome:R-MMU-3371568|reactome:R-MMU-3371571|reactome:R-MMU-450408|reactome:R-MMU-6798695|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:IjedYF1eneAZUEXux0xxZLvp6oI10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:A6ZI44	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-4283485|ensembl:ENSMUSP00000084846	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:a6zi44_mouse(display_long)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001170778.1|refseq:XP_006507272.1|ensembl:ENSMUSG00000030695(gene)|ensembl:ENSMUST00000087566(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006096"(glycolytic process)|go:"GO:0009408"(response to heat)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035094"(response to nicotine)|go:"GO:0043627"(response to estrogen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:QfjcGwfzA6vJ+Ip6oyWZf4ZCtQM10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9WUB3	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1371761|ensembl:ENSMUSP00000047564	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:pygm_mouse(display_long)|uniprotkb:Pygm(gene name)|psi-mi:Pygm(display_short)|uniprotkb:Myophosphorylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_035354.1|ensembl:ENSMUSG00000032648(gene)|ensembl:ENSMUST00000035269(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0010033"(response to organic substance)|go:"GO:0016208"(AMP binding)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030018"(Z disc)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:Q9WUB3|reactome:R-MMU-70221|interpro:IPR000811(Glycosyl transferase, family 35)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:x4zEkonduA5+JUL+3XYYPIVrIaY10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q8VCM7	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-6252682|ensembl:ENSMUSP00000037018|uniprotkb:Q8WUR3|uniprotkb:Q91ZP0	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:fibg_mouse(display_long)|uniprotkb:Fgg(gene name)|psi-mi:Fgg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000033860(gene)|ensembl:ENSMUST00000048486(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037581|mint:Q8VCM7|reactome:R-MMU-114608|reactome:R-MMU-140875|reactome:R-MMU-216083|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-381426|reactome:R-MMU-5674135|reactome:R-MMU-5686938|reactome:R-MMU-8957275|refseq:NP_598623.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:AmOFe/GrPI4CGlyrFHBM1QHxYOk10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9CQA3	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-432494|uniprotkb:Q3TF82|uniprotkb:Q9DC91|ensembl:ENSMUSP00000010007	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:sdhb_mouse(display_long)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)|uniprotkb:Sdhb(gene name)|psi-mi:Sdhb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_075863.2|ensembl:ENSMUSG00000009863(gene)|ensembl:ENSMUST00000010007(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0045273"(respiratory chain complex II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|mint:Q9CQA3|reactome:R-MMU-71403	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:867rMxM9LEdIwyu93mUmDNc1S0o10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:O35129	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-445002|uniprotkb:O89075|uniprotkb:Q61336|ensembl:ENSMUSP00000004375	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:phb2_mouse(display_long)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:Bap(gene name synonym)|uniprotkb:Bcap37(gene name synonym)|uniprotkb:Rea(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_031557.2|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:O35129|reactome:R-MMU-8949664|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|ensembl:ENSMUSG00000004264(gene)|ensembl:ENSMUST00000004375(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016363"(nuclear matrix)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0016477"(cell migration)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:h4pib54mBeQgOKCe/hib58LM26w10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P17710	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-773368|uniprotkb:E9PXQ3|uniprotkb:Q61659|uniprotkb:Q64476|uniprotkb:Q64479	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:hxk1_mouse(display_long)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Hexokinase, tumor isozyme(gene name synonym)|uniprotkb:Hk1(gene name)|psi-mi:Hk1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR001312(Hexokinase)|interpro:IPR022673|interpro:IPR019807|interpro:IPR022672|refseq:XP_006513305.1|refseq:XP_006513306.1|refseq:XP_006513307.1|refseq:XP_006513308.1|interpro:IPR043129|mint:P17710|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008865"(fructokinase activity)|go:"GO:0010359"(regulation of anion channel activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0047931"(glucosamine kinase activity)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|reactome:R-MMU-70171	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:x4T9LnTLPxq69q+uvfTwLT8gCn410090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P43274	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-913424|ensembl:ENSMUSP00000057308|uniprotkb:Q5EBH3	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:h14_mouse(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1 VAR.2(gene name synonym)|uniprotkb:H1e(gene name synonym)|uniprotkb:H1f4(gene name synonym)|uniprotkb:Hist1h1e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000051627(gene)|ensembl:ENSMUST00000062045(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P43274|reactome:R-MMU-140342|reactome:R-MMU-2559584|refseq:NP_056602.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:RbnBt0O11C8PWtfWp8tJJxsn00A10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P61982	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-359843|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q4FK44|uniprotkb:Q3UFD6|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSMUSP00000051223|ensembl:ENSMUSP00000143631	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:1433g_mouse(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_061359.2|ensembl:ENSMUSG00000051391(gene)|ensembl:ENSMUST00000055808(transcript)|ensembl:ENSMUST00000198270(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0006605"(protein targeting)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61982|reactome:R-MMU-111447|reactome:R-MMU-2565942|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-9614399	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P19253	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-445023|ensembl:ENSMUSP00000115722	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:rl13a_mouse(display_long)|uniprotkb:Transplantation antigen P198(gene name synonym)|uniprotkb:Tum-P198 antigen(gene name synonym)|uniprotkb:Rpl13a(gene name)|psi-mi:Rpl13a(display_short)|uniprotkb:P198(gene name synonym)|uniprotkb:Tstap198-7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_033464.2|ensembl:ENSMUSG00000074129(gene)|ensembl:ENSMUST00000150350(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0042592"(homeostatic process)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1901194"(negative regulation of formation of translation preinitiation complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005755(Ribosomal protein L13, eukaryotic/archaeal)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR023563|interpro:IPR036899|mint:P19253|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|rcsb pdb:6SWA	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:OHHQbay1m62ZSGYnKANekTh+C5Q10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P14206	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9CZ13	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-773751|uniprotkb:Q9CWL6|uniprotkb:Q3TV75|ensembl:ENSMUSP00000026743	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:qcr1_mouse(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 1(gene name synonym)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:Uqcrc1(gene name)|psi-mi:Uqcrc1(display_short)|uniprotkb:Core protein I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_079683.2|ensembl:ENSMUSG00000025651(gene)|ensembl:ENSMUST00000026743(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0014823"(response to activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:Q9CZ13|reactome:R-MMU-611105	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:oPlGhzsHLustrgdY4P+DdyJePbA10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q99KI0	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-444886|uniprotkb:Q3UDK9|uniprotkb:Q3ULG9|uniprotkb:Q3UNH7|uniprotkb:Q505P4|ensembl:ENSMUSP00000023116	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:acon_mouse(display_long)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Aco2(gene name)|psi-mi:Aco2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_542364.1|ensembl:ENSMUSG00000022477(gene)|ensembl:ENSMUST00000023116(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0043209"(myelin sheath)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q99KI0|reactome:R-MMU-71403|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:0NOVcGhBwl4qmtnlhX9jcsQMdSo10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:B7ZCI2	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20564738|ensembl:ENSMUSP00000117805	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:b7zci2_mouse(display_long)|uniprotkb:Nebl(gene name)|psi-mi:Nebl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000053702(gene)|ensembl:ENSMUST00000124270(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030018"(Z disc)|go:"GO:0031005"(filamin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0071691"(cardiac muscle thin filament assembly)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035631|interpro:IPR036028	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:+fiQSUMncpvsYK0M9GVSnPbO1nU10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P21550	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1634301|ensembl:ENSMUSP00000072620|ensembl:ENSMUSP00000104188|ensembl:ENSMUSP00000128714	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:enob_mouse(display_long)|uniprotkb:Eno3(gene name)|psi-mi:Eno3(display_short)|uniprotkb:Eno-3(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001129534.1|refseq:NP_031959.1|refseq:NP_001263214.1|refseq:XP_006532225.1|ensembl:ENSMUSG00000060600(gene)|ensembl:ENSMUST00000072841(transcript)|ensembl:ENSMUST00000108548(transcript)|ensembl:ENSMUST00000170716(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P21550|reactome:R-MMU-70171|reactome:R-MMU-70263	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:CN/5EMhCFqpjAxZ04UHwcLN+eRI10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9CPQ1	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-2934674|ensembl:ENSMUSP00000014457|ensembl:ENSMUSP00000122391|ensembl:ENSMUSP00000123609|uniprotkb:Q52KC6	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:cox6c_mouse(display_long)|uniprotkb:Cytochrome c oxidase polypeptide VIc(gene name synonym)|uniprotkb:Cox6c(gene name)|psi-mi:Cox6c(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUST00000156915(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004204(Cytochrome c oxidase subunit VIc)|interpro:IPR034884|interpro:IPR037169|mint:Q9CPQ1|ensembl:ENSMUST00000153512(transcript)|ensembl:ENSMUSG00000014313(gene)|ensembl:ENSMUST00000014457(transcript)|refseq:NP_444301.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:hOm5fzmi430bKn4GZxPSm14kr/c10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:A8DUV1	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20565375	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:a8duv1_mouse(display_long)|uniprotkb:Hbat1(gene name)|psi-mi:Hbat1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR000971(Globin, subset)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|interpro:IPR002338(Haemoglobin, alpha)|interpro:IPR002339(Haemoglobin, pi)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:qqaIfXJKAmDOpzUsRqXu8GYyldk10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P62259	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9CQ75	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-2255517|uniprotkb:Q9WUB2|ensembl:ENSMUSP00000014438	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:ndua2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B8 subunit(gene name synonym)|uniprotkb:Complex I-B8(gene name synonym)|uniprotkb:Ndufa2(gene name)|psi-mi:Ndufa2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_035015.2|ensembl:ENSMUSG00000014294(gene)|ensembl:ENSMUST00000014438(transcript)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR016464("NADH dehydrogenase [ubiquinone] (complex I), alpha subcomplex, subunit 2")|interpro:IPR036249|mint:Q9CQ75|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:Z2rI9xDggf8OO321yyMsskocTYM10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q06185	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-6666496|ensembl:ENSMUSP00000051222|uniprotkb:P70342	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:atp5i_mouse(display_long)|uniprotkb:Atp5me(gene name)|psi-mi:Atp5me(display_short)|uniprotkb:Atp5i(gene name synonym)|uniprotkb:Atp5k(gene name synonym)|uniprotkb:Lfm-1(gene name synonym)|uniprotkb:Lfm1(gene name synonym)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:Q06185|reactome:R-MMU-163210|reactome:R-MMU-8949613|ensembl:ENSMUSG00000050856(gene)|ensembl:ENSMUST00000049628(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|refseq:NP_031533.2	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:1hl0GhfM23wEB+OjR4PbmxMdNnQ10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P14148	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-445010|uniprotkb:Q80UR0|ensembl:ENSMUSP00000071616	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:rl7_mouse(display_long)|uniprotkb:Rpl7(gene name)|psi-mi:Rpl7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_035421.2|ensembl:ENSMUSG00000043716(gene)|ensembl:ENSMUST00000058437(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P14148|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:3mgKWwOhV0qZfTQwfsTkqol4iIY10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q99LC3	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-772722|uniprotkb:Q3UKK0|uniprotkb:Q8BL57|uniprotkb:Q9CW21|ensembl:ENSMUSP00000027478	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:nduaa_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Complex I-42kD(gene name synonym)|uniprotkb:Ndufa10(gene name)|psi-mi:Ndufa10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_077159.1|ensembl:ENSMUSG00000026260(gene)|ensembl:ENSMUST00000027478(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|mint:Q99LC3|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:PnMgq3QghxkpZvkzvgjuJUqkIqY10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q6P8J7	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20565591|ensembl:ENSMUSP00000022122	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:kcrs_mouse(display_long)|uniprotkb:Basic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:Sarcomeric mitochondrial creatine kinase(gene name synonym)|uniprotkb:Ckmt2(gene name)|psi-mi:Ckmt2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_940807.1|ensembl:ENSMUSG00000021622(gene)|ensembl:ENSMUST00000022122(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006603"(phosphocreatine metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:1901612"(cardiolipin binding)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:Q6P8J7|reactome:R-MMU-71288	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:WiCiHk8tlPTl97O2Pj1PBFf3Ifs10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9CXZ1	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-2934359|uniprotkb:Q9WUB1	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:ndus4_mouse(display_long)|uniprotkb:Ndufs4(gene name)|psi-mi:Ndufs4(display_short)|uniprotkb:Complex I-18 kDa(gene name synonym)|uniprotkb:Complex I-AQDQ(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 18 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR038532|reactome:R-MMU-6799198|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003016"(respiratory system process)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006954"(inflammatory response)|go:"GO:0007420"(brain development)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030534"(adult behavior)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045333"(cellular respiration)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050890"(cognition)|go:"GO:0051591"(response to cAMP)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070997"(neuron death)|go:"GO:0071453"(cellular response to oxygen levels)|go:"GO:0072593"(reactive oxygen species metabolic process)|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|go:"GO:0014876"(response to injury involved in regulation of muscle adaptation)|refseq:NP_035017.2|interpro:IPR006885(ETC complex I subunit conserved region)|mint:Q9CXZ1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:SbIn9Wz6DH4mipMhdL9qf55OJBo10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9CQ62	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-299499|ensembl:ENSMUSP00000029877|uniprotkb:Q9DCI7	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:decr_mouse(display_long)|uniprotkb:Decr1(gene name)|psi-mi:Decr1(display_short)|uniprotkb:2,4-dienoyl-CoA reductase [NADPH](gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000028223(gene)|ensembl:ENSMUST00000029877(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008670"("2,4-dienoyl-CoA reductase (NADPH) activity")|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902494"(catalytic complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q9CQ62|reactome:R-MMU-77288|go:"GO:0042802"(identical protein binding)|go:"GO:0070402"(NADPH binding)|refseq:NP_080448.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:Bh2PIoAhcHP1Sek3ELKceJj2xF410090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9JKS4	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-299323|ensembl:ENSMUSP00000022327|uniprotkb:Q6A038|uniprotkb:Q811P2|uniprotkb:Q811P3|uniprotkb:Q811P4|uniprotkb:Q811P5|uniprotkb:Q9D130|uniprotkb:Q9JKS3|uniprotkb:Q9R0Z1|uniprotkb:Q9WVH1|uniprotkb:Q9WVH2|uniprotkb:B2RSB0|uniprotkb:B7ZNT6	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:ldb3_mouse(display_long)|uniprotkb:Ldb3(gene name)|psi-mi:Ldb3(display_short)|uniprotkb:Z-band alternatively spliced PDZ-motif protein(gene name synonym)|uniprotkb:Protein cypher(gene name synonym)|uniprotkb:Protein oracle(gene name synonym)|uniprotkb:Kiaa0613(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000021798(gene)|ensembl:ENSMUST00000022327(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031143"(pseudopodium)|go:"GO:0031941"(filamentous actin)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR006643(ZASP)|interpro:IPR031847|interpro:IPR036034|mint:Q9JKS4|rcsb pdb:1WJL|refseq:NP_001034160.1|refseq:NP_001034161.1|refseq:NP_001034162.1|refseq:NP_001034163.1|refseq:NP_001034164.1|refseq:NP_001034165.1|refseq:NP_036048.3|refseq:XP_006519080.1|refseq:XP_017171508.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:cw40AYt3wGbDuNniByp+mt33HjQ10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:A0NA69	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20566409	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:a0na69_mouse(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	rcsb pdb:1DVF|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:RQo3C+MWcJaUs/b3TUEY/bvtILE10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P09671	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1635071|uniprotkb:Q8VEM5|uniprotkb:Q64670|ensembl:ENSMUSP00000007012	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:sodm_mouse(display_long)|uniprotkb:Sod2(gene name)|psi-mi:Sod2(display_short)|uniprotkb:Sod-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_038699.2|ensembl:ENSMUSG00000006818(gene)|ensembl:ENSMUST00000007012(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000303"(response to superoxide)|go:"GO:0001306"(age-dependent response to oxidative stress)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0001889"(liver development)|go:"GO:0003032"(detection of oxygen)|go:"GO:0003069"(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0003677"(DNA binding)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007507"(heart development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014823"(response to activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0035900"(response to isolation stress)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042311"(vasodilation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048666"(neuron development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048773"(erythrophore differentiation)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0071000"(response to magnetism)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902631"(negative regulation of membrane hyperpolarization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905932"(positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019831|interpro:IPR019832|interpro:IPR019833|interpro:IPR036314|interpro:IPR036324|mint:P09671|reactome:R-MMU-2151201|reactome:R-MMU-3299685	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:ElUPIiA1JSb5vbfqnibv3He227E10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P62918	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-6910319|ensembl:ENSMUSP00000004072|ensembl:ENSMUSP00000155657|uniprotkb:P25120|uniprotkb:Q3V288	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:rl8_mouse(display_long)|uniprotkb:Rpl8(gene name)|psi-mi:Rpl8(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62918|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000003970(gene)|ensembl:ENSMUST00000004072(transcript)|ensembl:ENSMUST00000229183(transcript)|go:"GO:0002181"(cytoplasmic translation)|refseq:NP_036183.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q3U0Q9	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20565507	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:q3u0q9_mouse(display_long)|uniprotkb:Tns1(gene name)|psi-mi:Tns1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR000980(SH2 motif)|interpro:IPR036860|interpro:IPR035012|interpro:IPR033929|go:"GO:0003779"(actin binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030055"(cell-substrate junction)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:lSlgLxhfMcppE0tQSv/Wk7xG5nQ10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q7TQI9	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20565534	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:q7tqi9_mouse(display_long)|uniprotkb:Lama2(gene name)|psi-mi:Lama2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR001791(Laminin G)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:k4Fbymfa9c60st1IdJetjPiGOyw10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q99L88	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-295943|uniprotkb:O35925|ensembl:ENSMUSP00000041294	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:sntb1_mouse(display_long)|uniprotkb:Sntb1(gene name)|psi-mi:Sntb1(display_short)|uniprotkb:Snt2b1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 1(gene name synonym)|uniprotkb:Syntrophin-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|mint:Q99L88|ensembl:ENSMUSG00000060429(gene)|ensembl:ENSMUST00000039769(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_057876.1|refseq:XP_006520734.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:s9YcOAVq5wEohYlPv5lLHlu62Sc10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9CR68	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1219616|uniprotkb:Q5SVV1|ensembl:ENSMUSP00000045284	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:ucri_mouse(display_long)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:Uqcrfs1(gene name)|psi-mi:Uqcrfs1(display_short)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_079986.1|mint:Q9CR68|reactome:R-MMU-611105|ensembl:ENSMUSG00000038462(gene)|ensembl:ENSMUST00000042834(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:nlXLFf9AMJ4fhZUsdE8cVraBuW410090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:A2AAJ9	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-16369923|ensembl:ENSMUSP00000158795|uniprotkb:A2AB85|uniprotkb:B2FDE7|uniprotkb:Q695L2|uniprotkb:Q811H7	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:obscn_mouse(display_long)|uniprotkb:Obscurin-RhoGEF(gene name synonym)|uniprotkb:Obscurin-myosin light chain kinase(gene name synonym)|uniprotkb:Obscn(gene name)|psi-mi:Obscn(display_short)|uniprotkb:Gm878(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000061462(gene)|ensembl:ENSMUST00000238536(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016604"(nuclear body)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031430"(M band)|go:"GO:0031432"(titin binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000719(Protein kinase, core)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020682|interpro:IPR035526|interpro:IPR035899|interpro:IPR036028|interpro:IPR036116|interpro:IPR036179	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:9+SPSrpnmR0BOj5cbx7l5aRgOJw10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:O08749	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-773199|uniprotkb:Q3TG55|uniprotkb:Q3U5W5|uniprotkb:Q3UWP7|uniprotkb:Q99LD3|ensembl:ENSMUSP00000106481	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:dldh_mouse(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Dld(gene name)|psi-mi:Dld(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_031887.2|ensembl:ENSMUSG00000020664(gene)|ensembl:ENSMUST00000110857(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043209"(myelin sheath)|go:"GO:0043544"(lipoamide binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:O08749|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-6783984|reactome:R-MMU-70268|reactome:R-MMU-70895|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:6j/8rw4lkNMW4Lo5sGoRdDJBk2w10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P63101	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-354751|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q3TSF1|uniprotkb:Q5EBQ1|ensembl:ENSMUSP00000022894|ensembl:ENSMUSP00000105990|ensembl:ENSMUSP00000105991	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:1433z_mouse(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:SEZ-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001240734.1|refseq:NP_001240735.1|refseq:NP_035870.1|refseq:XP_011243654.1|ensembl:ENSMUSG00000022285(gene)|ensembl:ENSMUST00000110361(transcript)|ensembl:ENSMUST00000110362(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|ensembl:ENSMUST00000022894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63101|reactome:R-MMU-111447|reactome:R-MMU-3769402|reactome:R-MMU-392517|reactome:R-MMU-430116|reactome:R-MMU-450604|reactome:R-MMU-512988|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9013700|reactome:R-MMU-9614399|dip:DIP-31894N	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P00405	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-773506|uniprotkb:Q85K21|ensembl:ENSMUSP00000080994	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:cox2_mouse(display_long)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:Mtco2(gene name)|psi-mi:Mtco2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:mt-Co2(gene name synonym)|uniprotkb:COX2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_904331.1|ensembl:ENSMUSG00000064354(gene)|ensembl:ENSMUST00000082405(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00405|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:oM1rnc+HJvDAF3+Z9fgK35b0UIw10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:B7ZNU9	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20566395|ensembl:ENSMUSP00000037324	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:b7znu9_mouse(display_long)|uniprotkb:Sntb2(gene name)|psi-mi:Sntb2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000041308(gene)|ensembl:ENSMUST00000047425(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:1ziMhHC/vGCm/OI++Ds8fuhhCXM10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q91YT0	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-2934319|ensembl:ENSMUSP00000042967	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:nduv1_mouse(display_long)|uniprotkb:Ndufv1(gene name)|psi-mi:Ndufv1(display_short)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000037916(gene)|ensembl:ENSMUST00000042497(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:Q91YT0|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_598427.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:xYJ5XxA1aRAaXMrlI8U+e9owOPU10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9QXX4	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-775952|uniprotkb:Q9CZF6|uniprotkb:Q9DCF5|ensembl:ENSMUSP00000015256|ensembl:ENSMUSP00000139571	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:cmc2_mouse(display_long)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)|uniprotkb:Slc25a13(gene name)|psi-mi:Slc25a13(display_short)|uniprotkb:Aralar2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001171043.1|refseq:NP_056644.1|ensembl:ENSMUSG00000015112(gene)|ensembl:ENSMUST00000015256(transcript)|ensembl:ENSMUST00000188414(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9QXX4|reactome:R-MMU-70263|reactome:R-MMU-8963693	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:c7qSgch4lV/J3PGriiqzNknznm010090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9D6R2	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-299873|ensembl:ENSMUSP00000127526|uniprotkb:Q3UAM8|uniprotkb:Q8C8A1|uniprotkb:Q9D1L1	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:idh3a_mouse(display_long)|uniprotkb:Idh3a(gene name)|psi-mi:Idh3a(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000032279(gene)|ensembl:ENSMUST00000167866(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q9D6R2|reactome:R-MMU-71403|refseq:NP_083849.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:JkEkbIT34WQdoOiBYA9kAao2lC010090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9QXS1	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-774583|uniprotkb:Q9QXR8|uniprotkb:Q9QXR9|uniprotkb:Q6S384|uniprotkb:Q6S389|uniprotkb:Q6S394|uniprotkb:Q9CS65|uniprotkb:Q9QUT2|uniprotkb:Q9QXQ8|uniprotkb:Q9QXQ9|uniprotkb:Q9QXR0|uniprotkb:Q9QXR1|uniprotkb:Q9QXR2|uniprotkb:Q9QXR3|uniprotkb:Q9QXR4|uniprotkb:Q9QXR5|uniprotkb:Q9QXR6|uniprotkb:Q9QXR7|uniprotkb:Q9QXS0|uniprotkb:Q9QXS2|uniprotkb:Q9QXS3|uniprotkb:E9QN87|ensembl:ENSMUSP00000073124	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:plec_mouse(display_long)|uniprotkb:Plectin-6(gene name synonym)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001157012.1|refseq:NP_001157014.1|refseq:NP_001157021.1|refseq:NP_001157675.1|refseq:NP_035247.2|refseq:NP_958791.2|refseq:NP_958796.2|dip:DIP-32004N|ensembl:ENSMUSG00000022565(gene)|ensembl:ENSMUST00000073418(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0043588"(skin development)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071944"(cell periphery)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR018159|interpro:IPR030269|interpro:IPR035915|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q9QXS1|rcsb pdb:1SH5|rcsb pdb:1SH6|rcsb pdb:4Q57|reactome:R-MMU-264870|reactome:R-MMU-446107	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:9cGCRGhjImLIGd9shNPJRdSpdoY10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9CZU6	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-773122|uniprotkb:Q3UDP3|ensembl:ENSMUSP00000005826	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:cisy_mouse(display_long)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym)|uniprotkb:Cs(gene name)|psi-mi:Cs(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_080720.1|ensembl:ENSMUSG00000005683(gene)|ensembl:ENSMUST00000005826(transcript)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0046912"(acyltransferase, acyl groups converted into alkyl on transfer)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|mint:Q9CZU6|rcsb pdb:3NZI|reactome:R-MMU-71403	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:0Ct6UHozD3vl5QxB0YOeKsSEUQw10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P82350	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20565959|uniprotkb:O35311|uniprotkb:O88490|ensembl:ENSMUSP00000098118|ensembl:ENSMUSP00000099451|ensembl:ENSMUSP00000130617	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:sgca_mouse(display_long)|uniprotkb:50 kDa dystrophin-associated glycoprotein(gene name synonym)|uniprotkb:Adhalin(gene name synonym)|uniprotkb:Sgca(gene name)|psi-mi:Sgca(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_033187.1|refseq:XP_011247138.1|ensembl:ENSMUSG00000001508(gene)|ensembl:ENSMUST00000100551(transcript)|ensembl:ENSMUST00000103162(transcript)|ensembl:ENSMUST00000166320(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016012"(sarcoglycan complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0045121"(membrane raft)|go:"GO:0061024"(membrane organization)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008908(Sarcoglycan alphaepsilon)|interpro:IPR015919(Cadherin-like)|interpro:IPR028658	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:OdpMfSbJh/qdwV/gMqg+q/pwSWk10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P51637	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-298576|ensembl:ENSMUSP00000074922	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P10493	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1032117|uniprotkb:Q8BQI3|uniprotkb:Q8C3U8|uniprotkb:Q8C9P6|uniprotkb:Q3TKX9|ensembl:ENSMUSP00000005532	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:nid1_mouse(display_long)|uniprotkb:Nid1(gene name)|psi-mi:Nid1(display_short)|uniprotkb:Ent(gene name synonym)|uniprotkb:Entactin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_035047.2|interpro:IPR026823|interpro:IPR036857|mint:P10493|rcsb pdb:1GL4|rcsb pdb:1H4U|rcsb pdb:1NPE|reactome:R-MMU-1474228|reactome:R-MMU-3000157|ensembl:ENSMUSG00000005397(gene)|ensembl:ENSMUST00000005532(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071944"(cell periphery)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003886(Nidogen, extracellular region)|interpro:IPR006605(G2 nidogen and fibulin G2F)|interpro:IPR009017(Green fluorescent protein-like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR024731	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:3dnqHnqAO3PlU6v5pchyqrF4UBg10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P07310	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-299493|ensembl:ENSMUSP00000146972	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:kcrm_mouse(display_long)|uniprotkb:Ckm(gene name)|psi-mi:Ckm(display_short)|uniprotkb:Ckmm(gene name synonym)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000030399(gene)|ensembl:ENSMUST00000208710(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006603"(phosphocreatine metabolic process)|go:"GO:0009408"(response to heat)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P07310|reactome:R-MMU-71288|refseq:NP_031736.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:HUwtOLpKEeqrxa326Rz+yjZ6/Mo10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P49817	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-1161338|uniprotkb:Q8C1X7|uniprotkb:Q8CBP4|uniprotkb:Q9QYH3|uniprotkb:Q9QYH4|ensembl:ENSMUSP00000007799|ensembl:ENSMUSP00000111116	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:cav1_mouse(display_long)|uniprotkb:Cav1(gene name)|psi-mi:Cav1(display_short)|uniprotkb:Cav(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000007655(gene)|ensembl:ENSMUST00000007799(transcript)|ensembl:ENSMUST00000115456(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0042060"(wound healing)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0052547"(regulation of peptidase activity)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070836"(caveola assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090398"(cellular senescence)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001258"(negative regulation of cation channel activity)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|interpro:IPR018361|mint:P49817|reactome:R-MMU-203615|reactome:R-MMU-203641|reactome:R-MMU-210991|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|reactome:R-MMU-4641262|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|reactome:R-MMU-9696273|reactome:R-MMU-9696264|refseq:NP_001229993.1|refseq:NP_031642.1|refseq:XP_006505037.1|refseq:XP_006505038.1|refseq:XP_006505039.1|dip:DIP-35140N	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:63vvAW/JPjuk8ZV3ZqoYdsy4umQ10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P47963	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-445016|uniprotkb:Q9CRZ9|uniprotkb:Q9DCH1|ensembl:ENSMUSP00000000756	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:rl13_mouse(display_long)|uniprotkb:A52(gene name synonym)|uniprotkb:Rpl13(gene name)|psi-mi:Rpl13(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_058018.2|ensembl:ENSMUSG00000000740(gene)|ensembl:ENSMUST00000000756(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0060348"(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P47963|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0022626"(cytosolic ribosome)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:s4+tKYYhhfFHM5TZCNIgbE2hQds10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q08284	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20564643	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:q08284_mouse(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR021996|go:"GO:0007596"(blood coagulation)|interpro:IPR037579	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:kU9SIvw8LtejHyKpN2cXStuUFXU10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:P70670	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-647147|uniprotkb:E9QMB1|ensembl:ENSMUSP00000089680	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:nacam_mouse(display_long)|uniprotkb:Gm1878(gene name synonym)|uniprotkb:Alpha-NAC, muscle-specific form(gene name synonym)|uniprotkb:Naca(gene name)|psi-mi:Naca(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001106670.1|refseq:NP_038636.2|ensembl:ENSMUSG00000061315(gene)|ensembl:ENSMUST00000092048(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051451"(myoblast migration)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:P70670	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:4QZh6JIwWgCTyZyvNxj5mmR6Bps10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9ERS2	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-2934630|ensembl:ENSMUSP00000105796|uniprotkb:Q9DC98|uniprotkb:Q9DCA1	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:nduad_mouse(display_long)|uniprotkb:Ndufa13(gene name)|psi-mi:Ndufa13(display_short)|uniprotkb:Grim19(gene name synonym)|uniprotkb:Cell death regulatory protein GRIM-19(gene name synonym)|uniprotkb:Complex I-B16.6(gene name synonym)|uniprotkb:Gene associated with retinoic and interferon-induced mortality 19 protein(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase B16.6 subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000036199(gene)|ensembl:ENSMUST00000110167(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR009346(GRIM-19)|mint:Q9ERS2|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_075801.1|refseq:XP_017168432.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:wgq95IYdQM3hRpOywBXA0Axqil010090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9D2N4	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-296019|uniprotkb:P97319|uniprotkb:Q61498|uniprotkb:Q61499|uniprotkb:Q9QZZ5|uniprotkb:Q9WUL9|uniprotkb:Q9WUM0	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:dtna_mouse(display_long)|uniprotkb:Dtna(gene name)|psi-mi:Dtna(display_short)|uniprotkb:Dtn(gene name synonym)|uniprotkb:Alpha-dystrobrevin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016014"(dystrobrevin complex)|refseq:NP_001272736.1|refseq:NP_001272739.1|refseq:NP_001272746.1|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|refseq:NP_034217.2|interpro:IPR017432(Distrobrevin)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR043145|refseq:XP_017173306.1|refseq:XP_017173308.1|refseq:XP_017173310.1|refseq:XP_017173311.1|refseq:XP_017173312.1|refseq:XP_017173313.1|refseq:XP_017173315.1	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:gqIbCFldISt+vbYeRHs3sswGPWU10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q05504	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-20564682	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:q05504_mouse(display_long)|uniprotkb:Col6a3(gene name)|psi-mi:Col6a3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042383"(sarcolemma)|go:"GO:0062023"(collagen-containing extracellular matrix)	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:bGfhWrmwdQEoDqhkRyYkMvL0Q9810090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q9CQC7	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-2255646|ensembl:ENSMUSP00000023514	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:ndub4_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase B15 subunit(gene name synonym)|uniprotkb:Complex I-B15(gene name synonym)|uniprotkb:Ndufb4(gene name)|psi-mi:Ndufb4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_080886.1|refseq:XP_001476621.1|refseq:XP_001478493.1|ensembl:ENSMUSG00000022820(gene)|ensembl:ENSMUST00000023514(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR009866(NADH-ubiquinone oxidoreductase, subunit NDUFB4)|mint:Q9CQC7|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:bOgcV3wmpY11CMgEaMUGzcugRiM10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q5SXR6	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-2308526|ensembl:ENSMUSP00000050220	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:q5sxr6_mouse(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	ensembl:ENSMUSG00000047126(gene)|ensembl:ENSMUST00000060766(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:zQkMlHHZuHQwJ3cU5pWAx/f6guc10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q8VHX6	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-400843|uniprotkb:Q6PAI6|uniprotkb:B2RY80|uniprotkb:B9EKT2|uniprotkb:Q9JJ38|ensembl:ENSMUSP00000064163	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:flnc_mouse(display_long)|uniprotkb:Flnc(gene name)|psi-mi:Flnc(display_short)|uniprotkb:Abpl(gene name synonym)|uniprotkb:Fln2(gene name synonym)|uniprotkb:Gamma-filamin(gene name synonym)|uniprotkb:Filamin-2(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:ABP-L(gene name synonym)|uniprotkb:ABP-280-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_001074654.1|refseq:NP_001298003.1|ensembl:ENSMUSG00000068699(gene)|mint:Q8VHX6|ensembl:ENSMUST00000065090(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030018"(Z disc)|go:"GO:0030029"(actin filament-based process)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030506"(ankyrin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|reactome:R-MMU-446353	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:xohwAtNkerMr1ZBB5Pi8QLYPo0Y10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:A2AKD7	uniprotkb:Q64727	intact:EBI-20565907|ensembl:ENSMUSP00000105350	intact:EBI-432047|uniprotkb:Q8BP32|uniprotkb:Q8BS46|uniprotkb:Q922C5|uniprotkb:Q922D9|ensembl:ENSMUSP00000022369	psi-mi:a2akd7_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)	psi-mi:vinc_mouse(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:Vcl(gene name)|psi-mi:Vcl(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566393|imex:IM-26422-8	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033254.2|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000109728(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030054"(cell junction)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428	refseq:NP_033528.3|ensembl:ENSMUSG00000021823(gene)|ensembl:ENSMUST00000022369(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0042383"(sarcolemma)|go:"GO:0043297"(apical junction assembly)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0048675"(axon extension)|go:"GO:0043034"(costamere)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:Q64727|rcsb pdb:5Y04|reactome:R-MMU-114608|reactome:R-MMU-445355|reactome:R-MMU-5674135|reactome:R-MMU-6798695	-	-	-	figure legend:Table S7, Fig. S5|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2019/04/15	rogid:eH3ONvPRVmL47+q1grujwLnpsTY10090	rogid:bfHsrHTLESS6CIctYpg0yX3N+UA10090	rigid:2Ul0Y6a0kGBeR/4ircLlNBpksZU	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P62267	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8313545|ensembl:ENSMUSP00000054490|uniprotkb:P39028|uniprotkb:Q542K7|intact:MINT-1857177	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:rs23_mouse(display_long)|uniprotkb:Rps23(gene name)|psi-mi:Rps23(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000049517(gene)|ensembl:ENSMUST00000051955(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034063"(stress granule assembly)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR005680(Ribosomal protein S23, eukaryotic/archaeal)|interpro:IPR006032(Ribosomal protein S12/S23)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P62267|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|refseq:NP_077137.1	-	-	comment:mint	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:MWZPvSL/G45ocaxA5AXKCkDQxNU10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P32233	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8429215|intact:MINT-1857949|ensembl:ENSMUSP00000020741	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:drg1_mouse(display_long)|uniprotkb:Drg1(gene name)|psi-mi:Drg1(display_short)|uniprotkb:Drg(gene name synonym)|uniprotkb:Nedd3(gene name synonym)|uniprotkb:Nedd-3(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 3(gene name synonym)|uniprotkb:Translation factor GTPase DRG1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_031905.1|dip:DIP-29599N|ensembl:ENSMUSG00000020457(gene)|ensembl:ENSMUST00000020741(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0042802"(identical protein binding)|go:"GO:1901673"(regulation of mitotic spindle assembly)|interpro:IPR004095(TGS)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR006074(GTP1/OBG, conserved site)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR027417|interpro:IPR031167|interpro:IPR031662|mint:P32233	-	-	comment:mint|function:May play a role in cell proliferation, differentiation and death	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:ViVCcUfhMIkjzW35gT5SItGCMt010090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9CX86	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8327584|intact:MINT-1868039|ensembl:ENSMUSP00000007980	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:roa0_mouse(display_long)|uniprotkb:Hnrnpa0(gene name)|psi-mi:Hnrnpa0(display_short)|uniprotkb:Hnrpa0(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_084148.1|ensembl:ENSMUSG00000007836(gene)|ensembl:ENSMUST00000007980(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q9CX86|reactome:R-MMU-72163|reactome:R-MMU-72203	-	-	comment:mint	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:HcbDTWHS4mZ3ITf0DfX/AjvfBBw10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P62315	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-7229109|uniprotkb:Q3UYM0|uniprotkb:P13641|intact:MINT-124808|ensembl:ENSMUSP00000002551	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:smd1_mouse(display_long)|uniprotkb:Snrpd1(gene name)|psi-mi:Snrpd1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_033252.1|ensembl:ENSMUSG00000002477(gene)|ensembl:ENSMUST00000002551(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034102|mint:P62315|reactome:R-MMU-191859|reactome:R-MMU-72163|reactome:R-MMU-72165	-	-	function:May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA|comment:mint	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:bfXwsV+IOjDPCoOJOoMQgECyiII10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q60936	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8347051|uniprotkb:Q8K0M1|uniprotkb:Q9D657|uniprotkb:Q9JHR3|uniprotkb:Q9DBR5|intact:MINT-1859515|ensembl:ENSMUSP00000027766|ensembl:ENSMUSP00000128290	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:coq8a_mouse(display_long)|uniprotkb:Coq8a(gene name)|psi-mi:Coq8a(display_short)|uniprotkb:Adck3(gene name synonym)|uniprotkb:Cabc1(gene name synonym)|uniprotkb:Chaperone activity of bc1 complex-like(gene name synonym)|uniprotkb:Coenzyme Q protein 8A(gene name synonym)|uniprotkb:aarF domain-containing protein kinase 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_075830.2|refseq:NP_001156762.1|refseq:XP_006497024.1|refseq:XP_006497025.1|ensembl:ENSMUSG00000026489(gene)|ensembl:ENSMUST00000027766(transcript)|ensembl:ENSMUST00000170472(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006744"(ubiquinone biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0043531"(ADP binding)|interpro:IPR004147(ABC-1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR034640|interpro:IPR034646|mint:Q60936	-	-	function:May be a chaperone-like protein essential for the proper conformation and functioning of protein complexes in the respiratory chain|comment:mint	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:mBL+f8T49kJm+ryI9VCRcUFyLZM10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P97379	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8319813|intact:MINT-1858459|uniprotkb:Q9R1B8|uniprotkb:Q3UL55|ensembl:ENSMUSP00000128244|ensembl:ENSMUSP00000128353|ensembl:ENSMUSP00000144456	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:g3bp2_mouse(display_long)|uniprotkb:G3bp2(gene name)|psi-mi:G3bp2(display_short)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_035946.2|refseq:NP_001074263.1|refseq:NP_001074266.1|refseq:XP_006534990.1|refseq:XP_006534991.1|ensembl:ENSMUSG00000029405(gene)|ensembl:ENSMUST00000164378(transcript)|ensembl:ENSMUST00000169094(transcript)|ensembl:ENSMUST00000202258(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR034377|interpro:IPR035979|interpro:IPR039539|mint:P97379	-	-	function:Probable scaffold protein that may be involved in mRNA transport|comment:mint	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:1MhDKzi09if4Beb23/9+ZTB0xKM10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P02468	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-7059830|intact:MINT-1031545	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:lamc1_mouse(display_long)|uniprotkb:Lamc1(gene name)|psi-mi:Lamc1(display_short)|uniprotkb:Lamb-2(gene name synonym)|uniprotkb:Lamc-1(gene name synonym)|uniprotkb:Laminin B2 chain(gene name synonym)|uniprotkb:Laminin-1 subunit gamma(gene name synonym)|uniprotkb:Laminin-2 subunit gamma(gene name synonym)|uniprotkb:Laminin-3 subunit gamma(gene name synonym)|uniprotkb:Laminin-4 subunit gamma(gene name synonym)|uniprotkb:Laminin-6 subunit gamma(gene name synonym)|uniprotkb:Laminin-7 subunit gamma(gene name synonym)|uniprotkb:Laminin-8 subunit gamma(gene name synonym)|uniprotkb:Laminin-9 subunit gamma(gene name synonym)|uniprotkb:Laminin-10 subunit gamma(gene name synonym)|uniprotkb:Laminin-11 subunit gamma(gene name synonym)|uniprotkb:S-laminin subunit gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	mint:P02468|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0007155"(cell adhesion)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000034(Laminin B)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|rcsb pdb:1KLO|rcsb pdb:1NPE|rcsb pdb:1TLE|rcsb pdb:4AQT|rcsb pdb:5MC9|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8874081|dip:DIP-41793N	-	-	comment:mint|function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:LTc4oIJUjQ8INjkodiPpXvL/rx010090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q08857	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8346984|intact:MINT-4090233|ensembl:ENSMUSP00000080974|ensembl:ENSMUSP00000126300|ensembl:ENSMUSP00000131832|ensembl:ENSMUSP00000133008|ensembl:ENSMUSP00000143061	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:cd36_mouse(display_long)|uniprotkb:Cd36(gene name)|psi-mi:Cd36(display_short)|uniprotkb:Platelet glycoprotein IV(gene name synonym)|uniprotkb:PAS IV(gene name synonym)|uniprotkb:PAS-4(gene name synonym)|uniprotkb:Glycoprotein IIIb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_031669.3|refseq:NP_001153028.1|refseq:NP_001153030.1|refseq:NP_001153027.1|refseq:NP_001153029.1|refseq:XP_006535683.1|refseq:XP_006535684.1|refseq:XP_006535685.1|refseq:XP_006535686.1|refseq:XP_006535687.1|refseq:XP_006535688.1|ensembl:ENSMUSG00000002944(gene)|ensembl:ENSMUST00000082367(transcript)|ensembl:ENSMUST00000165232(transcript)|ensembl:ENSMUST00000169095(transcript)|ensembl:ENSMUST00000170051(transcript)|ensembl:ENSMUST00000197890(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007263"(nitric oxide mediated signal transduction)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015636"(short-chain fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0015912"(short-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0019915"(lipid storage)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031526"(brush border membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033993"(response to lipid)|go:"GO:0034121"(regulation of toll-like receptor signaling pathway)|go:"GO:0034197"(triglyceride transport)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035325"(Toll-like receptor binding)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050892"(intestinal absorption)|go:"GO:0050909"(sensory perception of taste)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070508"(cholesterol import)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0070543"(response to linoleic acid)|go:"GO:0070892"(lipoteichoic acid immune receptor activity)|go:"GO:0071221"(cellular response to bacterial lipopeptide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0071726"(cellular response to diacyl bacterial lipopeptide)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090208"(positive regulation of triglyceride metabolic process)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098900"(regulation of action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140052"(cellular response to oxidised low-density lipoprotein particle stimulus)|go:"GO:0150024"(oxidised low-density lipoprotein particle clearance)|go:"GO:0150025"(oxidised low-density lipoprotein particle receptor activity)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1900227"(positive regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990379"(lipid transport across blood-brain barrier)|go:"GO:2000121"(regulation of removal of superoxide radicals)|go:"GO:2000334"(positive regulation of blood microparticle formation)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|interpro:IPR033076|mint:Q08857|reactome:R-MMU-114608|reactome:R-MMU-1236973|reactome:R-MMU-3000471|reactome:R-MMU-434313|reactome:R-MMU-5686938|reactome:R-MMU-6798695	-	-	comment:mint|function:Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:QDA1b0VEcVscBQlyYDRxFZMeAtg10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q7TMS5	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8365853|intact:MINT-2515312|uniprotkb:Q9R004|uniprotkb:Q9Z1T0	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:abcg2_mouse(display_long)|uniprotkb:Abcg2(gene name)|psi-mi:Abcg2(display_short)|uniprotkb:Abcp(gene name synonym)|uniprotkb:Bcrp1(gene name synonym)|uniprotkb:Breast cancer resistance protein 1 homolog(gene name synonym)|uniprotkb:Urate exporter(gene name synonym)|uniprotkb:ATP-binding cassette sub-family G member 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:XP_011239664.1|interpro:IPR027417|refseq:NP_036050.1|interpro:IPR030256|refseq:XP_006506213.1|mint:Q7TMS5|interpro:IPR043926|refseq:XP_006506211.1|refseq:XP_006506212.1|refseq:XP_006506214.1|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008514"(organic anion transmembrane transporter activity)|go:"GO:0008559"(ABC-type xenobiotic transporter activity)|go:"GO:0015143"(urate transmembrane transporter activity)|go:"GO:0015225"(biotin transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015711"(organic anion transport)|go:"GO:0015747"(urate transport)|go:"GO:0015878"(biotin transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019389"(glucuronoside metabolic process)|go:"GO:0031526"(brush border membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032217"(riboflavin transmembrane transporter activity)|go:"GO:0032218"(riboflavin transport)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042887"(amide transmembrane transporter activity)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046415"(urate metabolic process)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060136"(embryonic process involved in female pregnancy)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070633"(transepithelial transport)|go:"GO:0097744"(renal urate salt excretion)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1904479"(negative regulation of intestinal absorption)|go:"GO:1990748"(cellular detoxification)|go:"GO:1990961"(xenobiotic detoxification by transmembrane export across the plasma membrane)|go:"GO:1990962"(xenobiotic transport across blood-brain barrier)|reactome:R-MMU-189451|reactome:R-MMU-189483|reactome:R-MMU-917937|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR013525(ABC-2 type transporter)	-	-	comment:mint|function:"Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux (By similarity). May play a role in early stem cell self-renewal by blocking differentiation"	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:rswRcIVHDfUVUFIfX9BMI7UVii810090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P50752	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-7037406|ensembl:ENSMUSP00000107717|intact:MINT-4138660|uniprotkb:Q64377|uniprotkb:Q64360	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:tnnt2_mouse(display_long)|uniprotkb:Tnnt2(gene name)|psi-mi:Tnnt2(display_short)|uniprotkb:Cardiac muscle troponin T(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:XP_006529456.1|refseq:XP_006529457.1|refseq:XP_006529458.1|ensembl:ENSMUSG00000026414(gene)|ensembl:ENSMUST00000112087(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005861"(troponin complex)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007507"(heart development)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0030172"(troponin C binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0031013"(troponin I binding)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032972"(regulation of muscle filament sliding speed)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1990584"(cardiac Troponin complex)|interpro:IPR001978(Troponin)|interpro:IPR027707|interpro:IPR038077|mint:P50752|rcsb pdb:6KLT|rcsb pdb:6KLU|reactome:R-MMU-390522|refseq:NP_001123651.4|refseq:NP_001123652.1|refseq:NP_035749.1|refseq:NP_001123650.1|refseq:NP_001123648.1|refseq:NP_001123653.4	-	-	comment:mint|function:Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:Qaf6kFbJOB+rcI/aukloHa9LSCE10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P45952	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8344397|uniprotkb:Q64235|intact:MINT-1860219|ensembl:ENSMUSP00000072483	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:acadm_mouse(display_long)|uniprotkb:Acadm(gene name)|psi-mi:Acadm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_031408.1|ensembl:ENSMUSG00000062908(gene)|ensembl:ENSMUST00000072697(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0001889"(liver development)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006082"(organic acid metabolic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007507"(heart development)|go:"GO:0009409"(response to cold)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016853"(isomerase activity)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0030424"(axon)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|mint:P45952|reactome:R-MMU-77288|reactome:R-MMU-77346|reactome:R-MMU-77348	-	-	function:This enzyme is specific for acyl chain lengths of 4 to 16|comment:mint	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:Zfgo1s6CGy4mfJ3L1T7CHc6vQd810090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q922B2	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8315918|ensembl:ENSMUSP00000027602|uniprotkb:Q3U987|intact:MINT-1856918	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:sydc_mouse(display_long)|uniprotkb:Dars1(gene name)|psi-mi:Dars1(display_short)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:Dars(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000026356(gene)|ensembl:ENSMUST00000027602(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0045202"(synapse)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004523(Aspartyl-tRNA synthetase, class IIb, archea/euk type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q922B2|refseq:NP_803228.2	-	-	comment:mint	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:H7kUtRmDz/6VlO4kR9jYORfDUqI10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q8BP67	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-7914360|uniprotkb:P38663|uniprotkb:Q58EA4|intact:MINT-1857981|ensembl:ENSMUSP00000023269	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:rl24_mouse(display_long)|uniprotkb:Rpl24(gene name)|psi-mi:Rpl24(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_077180.1|ensembl:ENSMUSG00000098274(gene)|ensembl:ENSMUST00000023269(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:Q8BP67|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-6791226	-	-	comment:mint	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of810090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P26369	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8321355|intact:MINT-4139054|ensembl:ENSMUSP00000147013	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:u2af2_mouse(display_long)|uniprotkb:U2af2(gene name)|psi-mi:U2af2(display_short)|uniprotkb:U2af65(gene name synonym)|uniprotkb:U2 auxiliary factor 65 kDa subunit(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor large subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001192160.1|ensembl:ENSMUSG00000030435(gene)|ensembl:ENSMUST00000209099(transcript)|go:"GO:0000243"(commitment complex)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006529(U2 snRNP auxilliary factor, large subunit, splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P26369|rcsb pdb:2M52|rcsb pdb:3V4M|rcsb pdb:4RU2|rcsb pdb:4Z2X|rcsb pdb:5CXT|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856	-	-	comment:mint|function:Necessary for the splicing of pre-mRNA. Binds to the polypyrimidine tract of introns early during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:xtsNvQt0+260vwSlVp3X8aVxLE810090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q02357	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8319704|uniprotkb:Q78E45|uniprotkb:Q3TZ35|uniprotkb:P97446|uniprotkb:Q61302|uniprotkb:P70440|uniprotkb:Q61303|intact:MINT-255055|uniprotkb:Q3UH42|uniprotkb:Q3UHP2|uniprotkb:P97941|uniprotkb:Q3UYY7	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ank1_mouse(display_long)|uniprotkb:Ank1(gene name)|psi-mi:Ank1(display_short)|uniprotkb:Ank-1(gene name synonym)|uniprotkb:Erythrocyte ankyrin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001297365.1|refseq:NP_001297366.1|refseq:NP_001104253.1|interpro:IPR020683|refseq:NP_001264209.1|refseq:NP_112435.2|refseq:NP_001264215.1|refseq:NP_001264210.1|refseq:NP_001264218.1|mint:Q02357|interpro:IPR040745|interpro:IPR036770|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007165"(signal transduction)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031430"(M band)|go:"GO:0031672"(A band)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051117"(ATPase binding)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098662"(inorganic cation transmembrane transport)|reactome:R-MMU-445095|reactome:R-MMU-447043|reactome:R-MMU-6807878	-	-	comment:mint|function:"Attaches integral membrane proteins to cytoskeletal elements; binds to the erythrocyte membrane protein band 4.2, to Na-K ATPase, to the lymphocyte membrane protein GP85, and to the cytoskeletal proteins fodrin, tubulin, vimentin and desmin. Erythrocyte ankyrins also link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein; they retain most or all of these binding functions. In skeletal muscle, isoform Mu7 together with obscurin may provide a molecular link between the sarcoplasmic reticulum and myofibrils"	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:GprhtwVP5FEWl+UJrqrJoU8RjBw10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:O35129	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-445002|uniprotkb:O89075|uniprotkb:Q61336|ensembl:ENSMUSP00000004375	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:phb2_mouse(display_long)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:Bap(gene name synonym)|uniprotkb:Bcap37(gene name synonym)|uniprotkb:Rea(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_031557.2|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:O35129|reactome:R-MMU-8949664|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|ensembl:ENSMUSG00000004264(gene)|ensembl:ENSMUST00000004375(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016363"(nuclear matrix)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0016477"(cell migration)	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:h4pib54mBeQgOKCe/hib58LM26w10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9DCT2	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-772758|uniprotkb:Q8BTZ3|uniprotkb:Q8R073|ensembl:ENSMUSP00000005647	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ndus3_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym)|uniprotkb:Ndufs3(gene name)|psi-mi:Ndufs3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_080964.1|dip:DIP-32378N|ensembl:ENSMUSG00000005510(gene)|ensembl:ENSMUST00000005647(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016604"(nuclear body)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:Q9DCT2|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|reactome:R-MMU-9013408	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:2tQasToTy6/l6HeQwM+hTVH2Mow10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q91VM5	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-647431|uniprotkb:O35479|ensembl:ENSMUSP00000048153|ensembl:ENSMUSP00000147384	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:rmxl1_mouse(display_long)|uniprotkb:Rbmxl1(gene name)|psi-mi:Rbmxl1(display_short)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G-like 1(gene name synonym)|uniprotkb:RNA binding motif protein, X chromosome retrogene(gene name synonym)|uniprotkb:Rbmxrt(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:XP_006530838.1|refseq:XP_006530839.1|refseq:NP_001239018.1|refseq:NP_033059.2|ensembl:ENSMUSG00000037070(gene)|ensembl:ENSMUST00000049245(transcript)|ensembl:ENSMUST00000211719(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q91VM5	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:1aPRrfU5gcmzCimlfwuz07A4gyA10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P09541	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-20567045	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:myl4_mouse(display_long)|uniprotkb:MLC1EMB(gene name synonym)|uniprotkb:Myosin light chain 1, atrial/fetal isoform(gene name synonym)|uniprotkb:Myl4(gene name)|psi-mi:Myl4(display_short)|uniprotkb:Mlc1a(gene name synonym)|uniprotkb:Myla(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0031672"(A band)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0060048"(cardiac muscle contraction)|reactome:R-MMU-390522|interpro:IPR011992(EF-Hand type)|interpro:IPR002048(Calcium-binding EF-hand)|mint:P09541	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:aD1Fs+tY7Wxoc2RdDx2+vXHvI3Q10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P62855	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-6260985|ensembl:ENSMUSP00000026420|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:P02383	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:rs26_mouse(display_long)|uniprotkb:Rps26(gene name)|psi-mi:Rps26(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000025362(gene)|ensembl:ENSMUST00000026420(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|mint:P62855|refseq:NP_038793.2	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P17426	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-775189|ensembl:ENSMUSP00000082519|ensembl:ENSMUSP00000127842	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ap2a1_mouse(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-1(gene name synonym)|uniprotkb:Alpha1-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha A subunit(gene name synonym)|uniprotkb:Alpha-adaptin A(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-A large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein A(gene name synonym)|uniprotkb:Ap2a1(gene name)|psi-mi:Ap2a1(display_short)|uniprotkb:Adtaa(gene name synonym)|uniprotkb:Clapa1(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001070732.1|refseq:NP_031484.1|ensembl:ENSMUSG00000060279(gene)|ensembl:ENSMUST00000085399(transcript)|ensembl:ENSMUST00000166972(transcript)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0032433"(filopodium tip)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0140312"(cargo adaptor activity)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|mint:P17426|reactome:R-MMU-177504|reactome:R-MMU-2132295|reactome:R-MMU-416993|reactome:R-MMU-437239|reactome:R-MMU-5099900|reactome:R-MMU-5140745|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8866427|reactome:R-MMU-8964038	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:Dd6Q+Et/LTlmo5qpro2Zaeq0dMc10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P54071	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-773401|uniprotkb:Q8C2R9|uniprotkb:Q9EQK1|ensembl:ENSMUSP00000103007	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:idhp_mouse(display_long)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:Idh2(gene name)|psi-mi:Idh2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_766599.2|ensembl:ENSMUSG00000030541(gene)|ensembl:ENSMUST00000107384(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004448"(isocitrate dehydrogenase activity)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P54071|rcsb pdb:5H3E|rcsb pdb:5H3F|reactome:R-MMU-2151201|reactome:R-MMU-71403	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:CkBZHIePaNGTtcgyqEf03oczVM010090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q8BFR5	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-299611|ensembl:ENSMUSP00000095656|uniprotkb:Q497E7|uniprotkb:Q6P919	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:eftu_mouse(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000073838(gene)|ensembl:ENSMUST00000098048(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:Q8BFR5|go:"GO:0042645"(mitochondrial nucleoid)|refseq:NP_001157185.1|refseq:NP_766333.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:ax4f72KkJMxjxZD3ZClHh/oby3k10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P11152	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-8801123|ensembl:ENSMUSP00000015712|ensembl:ENSMUSP00000132259|uniprotkb:Q05956|uniprotkb:Q542L4|uniprotkb:Q9D3M9|uniprotkb:Q9DCM8	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:lipl_mouse(display_long)|uniprotkb:Lpl(gene name)|psi-mi:Lpl(display_short)|uniprotkb:Phospholipase A1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0008970"(phospholipase A1 activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016298"(lipase activity)|go:"GO:0017129"(triglyceride binding)|go:"GO:0019432"(triglyceride biosynthetic process)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0004806"(triglyceride lipase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0052739"(phosphatidylserine 1-acylhydrolase activity)|go:"GO:0052740"(1-acyl-2-lysophosphatidylserine acylhydrolase activity)|go:"GO:0055096"(low-density lipoprotein particle mediated signaling)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:1900077"(negative regulation of cellular response to insulin stimulus)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000734(Lipase)|interpro:IPR001024(Lipoxygenase, LH2)|go:"GO:0042627"(chylomicron)|interpro:IPR013818(Lipase, N-terminal)|interpro:IPR016272(Lipoprotein lipase, LIPH)|interpro:IPR029058|interpro:IPR033906|interpro:IPR036392|mint:P11152|reactome:R-MMU-8963889|reactome:R-MMU-8963901|reactome:R-MMU-975634|interpro:IPR002330(Lipoprotein lipase)|ensembl:ENSMUSG00000015568(gene)|ensembl:ENSMUST00000015712(transcript)|ensembl:ENSMUST00000168401(transcript)|go:"GO:0004465"(lipoprotein lipase activity)|go:"GO:0004620"(phospholipase activity)|refseq:NP_032535.2	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:/olkwrWXSqe8ZnXKzPwBVm74uc010090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9JJI8	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-4286104|ensembl:ENSMUSP00000080741|ensembl:ENSMUSP00000102209|ensembl:ENSMUSP00000102211|ensembl:ENSMUSP00000102213	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:rl38_mouse(display_long)|uniprotkb:Rpl38(gene name)|psi-mi:Rpl38(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001041522.1|refseq:NP_001041523.1|refseq:NP_075861.1|refseq:XP_006534072.1|go:"GO:0033291"(eukaryotic 80S initiation complex)|go:"GO:0034463"(90S preribosome assembly)|go:"GO:0042474"(middle ear morphogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0048318"(axial mesoderm development)|interpro:IPR002675(Ribosomal protein L38e)|interpro:IPR038464|mint:Q9JJI8|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0022626"(cytosolic ribosome)|refseq:XP_017170209.1|ensembl:ENSMUSG00000057322(gene)|ensembl:ENSMUST00000077915(transcript)|ensembl:ENSMUST00000082092(transcript)|ensembl:ENSMUST00000106599(transcript)|ensembl:ENSMUST00000106602(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022618"(ribonucleoprotein complex assembly)|go:"GO:0022625"(cytosolic large ribosomal subunit)	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:rs3Syk5fg3yYGcZm6oXRx/ORc2Q10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P18760	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-1183994|ensembl:ENSMUSP00000147514	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:cof1_mouse(display_long)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_031713.1|ensembl:ENSMUSG00000056201(gene)|ensembl:ENSMUST00000209469(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P18760|dip:DIP-38073N	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:nw/9u2+2nq9Ef43SapV43MeOtjE10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9Z2I8	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2107688|uniprotkb:Q3T9B8|uniprotkb:Q3TJQ5|uniprotkb:Q3TK63|uniprotkb:Q66JT3|uniprotkb:Q7TMY3|uniprotkb:Q80VV1|uniprotkb:Q8K2K9|ensembl:ENSMUSP00000144827	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:sucb2_mouse(display_long)|uniprotkb:Suclg2(gene name)|psi-mi:Suclg2(display_short)|uniprotkb:GTP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-G chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001313487.1|refseq:NP_035637.2|ensembl:ENSMUSG00000061838(gene)|ensembl:ENSMUST00000204224(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0004777"("succinate-semialdehyde dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034722|mint:Q9Z2I8|reactome:R-MMU-71403	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:V1vkzx6MwooUIe9d/A66CRAoygA10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:E9PV24	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-6252659|ensembl:ENSMUSP00000133117|intact:EBI-8314642|intact:MINT-1863401|uniprotkb:Q99K47	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:fiba_mouse(display_long)|uniprotkb:Fga(gene name)|psi-mi:Fga(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_034326.1|ensembl:ENSMUSG00000028001(gene)|ensembl:ENSMUST00000166581(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072377"(blood coagulation, common pathway)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|go:"GO:0042730"(fibrinolysis)|interpro:IPR021996|interpro:IPR036056|interpro:IPR037579|mint:E9PV24|reactome:R-MMU-114608|reactome:R-MMU-140875|reactome:R-MMU-216083|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-381426|reactome:R-MMU-5674135|reactome:R-MMU-5686938|reactome:R-MMU-8957275|interpro:IPR020837|refseq:NP_001104518.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:c9u+80j+sNgwjFuQ5vnHBVKgLCg10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q8BG05	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2735601|uniprotkb:Q8BHF8|ensembl:ENSMUSP00000088298|ensembl:ENSMUSP00000107595	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:roa3_mouse(display_long)|uniprotkb:Hnrnpa3(gene name)|psi-mi:Hnrnpa3(display_short)|uniprotkb:Hnrpa3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_444493.1|refseq:NP_666242.2|refseq:NP_932758.1|ensembl:ENSMUSG00000059005(gene)|ensembl:ENSMUST00000090792(transcript)|ensembl:ENSMUST00000111964(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:Q8BG05|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:XP_011237818.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:KcZjXvHON9QZSqHWi4nWSDz/HtE10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P60335	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-309059|ensembl:ENSMUSP00000054863	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:pcbp1_mouse(display_long)|uniprotkb:Pcbp1(gene name)|psi-mi:Pcbp1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_035995.1|ensembl:ENSMUSG00000051695(gene)|ensembl:ENSMUST00000053015(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008494"(translation activator activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P60335|reactome:R-MMU-72163|reactome:R-MMU-72203	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:x72fawo4plQ+ipfqIoREIDHc2bA10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q91YT0	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2934319|ensembl:ENSMUSP00000042967	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:nduv1_mouse(display_long)|uniprotkb:Ndufv1(gene name)|psi-mi:Ndufv1(display_short)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000037916(gene)|ensembl:ENSMUST00000042497(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:Q91YT0|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_598427.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:xYJ5XxA1aRAaXMrlI8U+e9owOPU10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q8BWT1	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-1634016|uniprotkb:Q8JZR8|intact:EBI-4285676|uniprotkb:Q3TIT9|ensembl:ENSMUSP00000037348	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:thim_mouse(display_long)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acaa2(gene name)|psi-mi:Acaa2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_803421.1|ensembl:ENSMUSG00000036880(gene)|ensembl:ENSMUST00000041053(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q8BWT1|reactome:R-MMU-77289	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:15aWO97WJBNGYD449bAgjVjkgTY10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9D6K8	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-20567028|ensembl:ENSMUSP00000033541|uniprotkb:Q80VT2|uniprotkb:Q80YD9|uniprotkb:Q8BSM8|uniprotkb:Q9D617	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:fund2_mouse(display_long)|uniprotkb:Hepatitis C virus core-binding protein 6(gene name synonym)|uniprotkb:Fundc2(gene name)|psi-mi:Fundc2(display_short)|uniprotkb:Hcbp6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000031198(gene)|ensembl:ENSMUST00000033541(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005739"(mitochondrion)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|interpro:IPR007014(FUN14)|refseq:NP_080402.3	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:MpCTAX+UQmwhE0MxCTrEZN+bNqw10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P61979	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-299907|ensembl:ENSMUSP00000039269|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q60577|uniprotkb:Q8BGQ8|uniprotkb:Q922Y7|uniprotkb:Q96J62	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:hnrpk_mouse(display_long)|uniprotkb:Hnrnpk(gene name)|psi-mi:Hnrnpk(display_short)|uniprotkb:Hnrpk(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUST00000043269(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0002102"(podosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|ensembl:ENSMUSG00000021546(gene)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:1990829"(C-rich single-stranded DNA binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve)|interpro:IPR004087(K Homology)|go:"GO:0051117"(ATPase binding)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61979|reactome:R-MMU-4570464|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904322"(cellular response to forskolin)|refseq:NP_001288269.1|refseq:NP_001288270.1|refseq:NP_001288272.1|refseq:NP_001288273.1|refseq:NP_001288274.1|refseq:XP_017170884.1|refseq:XP_017170885.1|refseq:NP_079555.1|refseq:XP_006517166.1|refseq:XP_006517167.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9WUM5	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-773740|uniprotkb:Q8C2C3|uniprotkb:Q9DBA3|uniprotkb:Q9DCI8|ensembl:ENSMUSP00000065113	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:suca_mouse(display_long)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym)|uniprotkb:Suclg1(gene name)|psi-mi:Suclg1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_063932.2|ensembl:ENSMUSG00000052738(gene)|ensembl:ENSMUST00000064740(transcript)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|go:"GO:0019003"(GDP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR033847|interpro:IPR036291|mint:Q9WUM5|reactome:R-MMU-71403	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:Bb1b4P5dXlGyek/f6p8+X0Dbzt010090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q8VDN2	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-444536|ensembl:ENSMUSP00000039657|uniprotkb:Q91Z09	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:at1a1_mouse(display_long)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_659149.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8VDN2|reactome:R-MMU-5578775|reactome:R-MMU-936837|ensembl:ENSMUSG00000033161(gene)|ensembl:ENSMUST00000036493(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|dip:DIP-31885N	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:gz0ThqOMMsrl71IqGW0z8wbiqL410090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9D883	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-6876958|ensembl:ENSMUSP00000014684|uniprotkb:Q564E4|uniprotkb:Q99LX2|uniprotkb:Q9CZ98	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:u2af1_mouse(display_long)|uniprotkb:U2af1(gene name)|psi-mi:U2af1(display_short)|uniprotkb:U2 auxiliary factor 35 kDa subunit(gene name synonym)|uniprotkb:U2 snRNP auxiliary factor small subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	go:"GO:0005681"(spliceosomal complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050733"(RS domain binding)|go:"GO:0089701"(U2AF complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR009145(U2 auxiliary factor small subunit)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9D883|reactome:R-MMU-159236|reactome:R-MMU-72163|reactome:R-MMU-72187|reactome:R-MMU-73856|ensembl:ENSMUSG00000061613(gene)|ensembl:ENSMUST00000014684(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|refseq:NP_001157241.1|refseq:NP_077149.2	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:W7mwbEH9hsB3BfLk5hmV+Uj9N4410090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q91WD5	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-772751|uniprotkb:Q3U5Y9|uniprotkb:Q3UJX7|uniprotkb:Q99L23|uniprotkb:Q3TNA8|ensembl:ENSMUSP00000013737	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ndus2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)|uniprotkb:Ndufs2(gene name)|psi-mi:Ndufs2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_694704.1|ensembl:ENSMUSG00000013593(gene)|ensembl:ENSMUST00000013737(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:Q91WD5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:dk8e26C1hIdTZvDnX5nE1n+juwk10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P53986	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-20566991|ensembl:ENSMUSP00000045216	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:mot1_mouse(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:Slc16a1(gene name)|psi-mi:Slc16a1(display_short)|uniprotkb:Mct1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000032902(gene)|ensembl:ENSMUST00000046212(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032094"(response to food)|go:"GO:0035873"(lactate transmembrane transport)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051780"(behavioral response to nutrient)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:1905039"(carboxylic acid transmembrane transport)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|interpro:IPR020846|interpro:IPR030757|interpro:IPR036259|reactome:R-MMU-210991|reactome:R-MMU-433692|reactome:R-MMU-70268|refseq:NP_033222.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:PWuXBrgjzruB64gWVw5PpvlfYqI10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q3V132	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2310226|uniprotkb:Q80W28|ensembl:ENSMUSP00000088723	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:adt4_mouse(display_long)|uniprotkb:Slc25a31(gene name)|psi-mi:Slc25a31(display_short)|uniprotkb:Aac4(gene name synonym)|uniprotkb:Ant4(gene name synonym)|uniprotkb:Sfec(gene name synonym)|uniprotkb:Adenine nucleotide translocator 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein 4(gene name synonym)|uniprotkb:Sperm flagellar energy carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 31(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_848473.2|ensembl:ENSMUSG00000069041(gene)|ensembl:ENSMUST00000091184(transcript)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031514"(motile cilium)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:Q3V132	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:oFuX3ZylOwMxbo+nGKThnffmbkg10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q01815	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-644904|uniprotkb:Q04476|uniprotkb:Q61242|uniprotkb:Q99242|ensembl:ENSMUSP00000075021|ensembl:ENSMUSP00000077433	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:cac1c_mouse(display_long)|uniprotkb:Voltage-gated calcium channel subunit alpha Cav1.2(gene name synonym)|uniprotkb:Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle(gene name synonym)|uniprotkb:Mouse brain class C(gene name synonym)|uniprotkb:MELC-CC(gene name synonym)|uniprotkb:Cacna1c(gene name)|psi-mi:Cacna1c(display_short)|uniprotkb:Cach2(gene name synonym)|uniprotkb:Cacn2(gene name synonym)|uniprotkb:Cacnl1a1(gene name synonym)|uniprotkb:Cchl1a1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001153005.1|ensembl:ENSMUSG00000051331(gene)|ensembl:ENSMUST00000075591(transcript)|ensembl:ENSMUST00000078320(transcript)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002520"(immune system development)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007507"(heart development)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008331"(high voltage-gated calcium channel activity)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030018"(Z disc)|go:"GO:0030073"(insulin secretion)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042383"(sarcolemma)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060083"(smooth muscle contraction involved in micturition)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086007"(voltage-gated calcium channel activity involved in cardiac muscle cell action potential)|go:"GO:0086012"(membrane depolarization during cardiac muscle cell action potential)|go:"GO:0086045"(membrane depolarization during AV node cell action potential)|go:"GO:0086056"(voltage-gated calcium channel activity involved in AV node cell action potential)|go:"GO:0086065"(cell communication involved in cardiac conduction)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098912"(membrane depolarization during atrial cardiac muscle cell action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1904879"(positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR002077(Voltage-dependent calcium channel, alpha-1 subunit)|interpro:IPR005446(Voltage-dependent calcium channel, L-type, alpha-1 subunit)|interpro:IPR005451(Voltage-dependent calcium channel, L-type, alpha-1C subunit)|interpro:IPR005821(Ion transport)|interpro:IPR014873(Voltage-dependent calcium channel, alpha-1 subunit, IQ domain)|interpro:IPR027359|interpro:IPR031649|interpro:IPR031688|reactome:R-MMU-422356|reactome:R-MMU-5576892|reactome:R-MMU-5576893|dip:DIP-32232N	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:fl3WWY9hkShz2t1DpMRNX0t2OgU10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9QYB5	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-774301|uniprotkb:Q8JZT6|uniprotkb:Q9D2M5|uniprotkb:Q9QYB6|ensembl:ENSMUSP00000025999|ensembl:ENSMUSP00000157697|ensembl:ENSMUSP00000157955|ensembl:ENSMUSP00000158149	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:addg_mouse(display_long)|uniprotkb:Adducin-like protein 70(gene name synonym)|uniprotkb:Add3(gene name)|psi-mi:Add3(display_short)|uniprotkb:Addl(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001264029.1|refseq:NP_001157572.1|refseq:NP_001157571.1|refseq:NP_038786.2|ensembl:ENSMUSG00000025026(gene)|ensembl:ENSMUST00000025999(transcript)|ensembl:ENSMUST00000236296(transcript)|ensembl:ENSMUST00000237301(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0042493"|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR027772|interpro:IPR036409|mint:Q9QYB5|reactome:R-MMU-5223345|reactome:R-MMU-9013405|reactome:R-MMU-9035034|ensembl:ENSMUST00000237430(transcript)	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:HQdionKFljt+1U837+sdt4rR4fI10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9WV02	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-6393090|ensembl:ENSMUSP00000110374|ensembl:ENSMUSP00000110378|uniprotkb:Q8C2U6|uniprotkb:Q9R0Y0	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:rbmx_mouse(display_long)|uniprotkb:Rbmx(gene name)|psi-mi:Rbmx(display_short)|uniprotkb:Hnrnpg(gene name synonym)|uniprotkb:Hnrpg(gene name synonym)|uniprotkb:Rbmxp1(gene name synonym)|uniprotkb:Rbmxrt(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000031134(gene)|ensembl:ENSMUST00000114726(transcript)|ensembl:ENSMUST00000114730(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9WV02|reactome:R-MMU-72163|reactome:R-MMU-72203|reactome:R-MMU-9013418|reactome:R-MMU-9013422|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273|refseq:NP_035382.1|refseq:NP_001160095.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:ifrLkzQpL8VIx6Dmsc8SBVQzDSU10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P63038	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9CXY6	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2312782|uniprotkb:Q3U083|uniprotkb:Q5RKG0|uniprotkb:Q8CCY9|uniprotkb:Q99KS3|ensembl:ENSMUSP00000001042	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ilf2_mouse(display_long)|uniprotkb:Ilf2(gene name)|psi-mi:Ilf2(display_short)|uniprotkb:Nf45(gene name synonym)|uniprotkb:Nuclear factor of activated T-cells 45 kDa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_080650.1|ensembl:ENSMUSG00000001016(gene)|ensembl:ENSMUST00000001042(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006561(DZF)|interpro:IPR043519|mint:Q9CXY6|rcsb pdb:4AT7|rcsb pdb:4AT8|rcsb pdb:4AT9|rcsb pdb:4ATB|reactome:R-MMU-6798695	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:HwUDuY6Ev7csoTThxZCW8nJT88o10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9CPU4	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2935061|uniprotkb:Q3UXC5|uniprotkb:Q9D834|ensembl:ENSMUSP00000028005	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:mgst3_mouse(display_long)|uniprotkb:Mgst3(gene name)|psi-mi:Mgst3(display_short)|uniprotkb:Glutathione peroxidase MGST3(gene name synonym)|uniprotkb:Microsomal glutathione S-transferase III(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	go:"GO:0004464"(leukotriene-C4 synthase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001129("Membrane-associated, eicosanoid and glutathione metabolism (MAPEG)")|interpro:IPR023352|reactome:R-MMU-156590|reactome:R-MMU-5423646|go:"GO:0004364"(glutathione transferase activity)|ensembl:ENSMUSG00000026688(gene)|ensembl:ENSMUST00000028005(transcript)|refseq:NP_079845.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:uxWRd47vtmR9RmuPoh7cfAmDgvs10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9CY58	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-6393149|ensembl:ENSMUSP00000039110|uniprotkb:Q8BHS2|uniprotkb:Q8BHU0|uniprotkb:Q91WP3|uniprotkb:Q9CSN0|uniprotkb:Q9DBY6	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:pairb_mouse(display_long)|uniprotkb:Serbp1(gene name)|psi-mi:Serbp1(display_short)|uniprotkb:Pairbp1(gene name synonym)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000036371(gene)|ensembl:ENSMUST00000042990(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q9CY58|refseq:NP_001107037.1|refseq:NP_001107038.1|refseq:NP_080090.2	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:SXRlAj8j23iy2v1N+Cx7gT7g4lM10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9JJG0	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-20566959|uniprotkb:Q3TN02|uniprotkb:Q811U0|uniprotkb:Q8BQD4|uniprotkb:Q99KQ6	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:tacc2_mouse(display_long)|uniprotkb:Tacc2(gene name)|psi-mi:Tacc2(display_short)|uniprotkb:MNCb-3527(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	interpro:IPR039915|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022008"(neurogenesis)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0032886"(regulation of microtubule-based process)|refseq:NP_001334566.1|refseq:NP_067289.2|refseq:NP_996738.2|interpro:IPR007707(Transforming acidic coiled-coil-containing)	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:aP/Eo3SRmT/w4HFKib0/W87ykIw10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q7TMM9	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2255578|ensembl:ENSMUSP00000060246	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:tbb2a_mouse(display_long)|uniprotkb:Tubb2(gene name synonym)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_033476.1|ensembl:ENSMUSG00000058672(gene)|ensembl:ENSMUST00000056427(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q7TMM9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q91VK1	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-646202|uniprotkb:Q9D0N4|ensembl:ENSMUSP00000020856	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:bzw2_mouse(display_long)|uniprotkb:Bzw2(gene name)|psi-mi:Bzw2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_080116.2|ensembl:ENSMUSG00000020547(gene)|ensembl:ENSMUST00000020856(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR043510|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:JcMA6deOV3O1HtL/V+pBIn59bgU10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q8BMK4	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-689057|uniprotkb:Q8BTK8|uniprotkb:Q8R3F2|uniprotkb:B2RRB4|ensembl:ENSMUSP00000050336|ensembl:ENSMUSP00000130304	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ckap4_mouse(display_long)|uniprotkb:Ckap4(gene name)|psi-mi:Ckap4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_780660.1|ensembl:ENSMUSG00000046841(gene)|ensembl:ENSMUST00000053871(transcript)|ensembl:ENSMUST00000167671(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR028428|mint:Q8BMK4|reactome:R-MMU-381426|reactome:R-MMU-5683826|reactome:R-MMU-6798695|reactome:R-MMU-8957275|reactome:R-MMU-9696264|reactome:R-MMU-9696270	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:mmjhipfUChfmrPP+NpygwvlH2Zc10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:O70133	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2657677|uniprotkb:O35931|uniprotkb:O54703|uniprotkb:Q5FWY1|uniprotkb:Q6R5F7|uniprotkb:Q9CSA2	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:dhx9_mouse(display_long)|uniprotkb:Dhx9(gene name)|psi-mi:Dhx9(display_short)|uniprotkb:Ddx9(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_031868.2|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR007502(Helicase-associated region)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005844"(polysome)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904973"(positive regulation of viral translation)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|rcsb pdb:1UIL|rcsb pdb:1WHQ|rcsb pdb:2RS6|rcsb pdb:2RS7|reactome:R-MMU-1810476|reactome:R-MMU-3134963|reactome:R-MMU-72163|interpro:IPR027417|mint:O70133|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:8NHxvbw0StglewhGm3e7Pi/8oOg10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q3V384	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-20565389|uniprotkb:Q5EBH5|uniprotkb:Q8K1E9|ensembl:ENSMUSP00000036149	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:afg1l_mouse(display_long)|uniprotkb:Lactation elevated protein 1(gene name synonym)|uniprotkb:Afg1l(gene name)|psi-mi:Afg1l(display_short)|uniprotkb:Lace1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_665686.2|ensembl:ENSMUSG00000038302(gene)|ensembl:ENSMUST00000041024(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|interpro:IPR005654(AFG1-like ATPase)|interpro:IPR027417	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:ucW93YB8cj+s2L/5VeldLdnEm4s10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q6ZWX6	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-1202234|uniprotkb:Q3TIQ0|ensembl:ENSMUSP00000071214	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:if2a_mouse(display_long)|uniprotkb:Eif2s1(gene name)|psi-mi:Eif2s1(display_short)|uniprotkb:Eif2a(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2 subunit alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_080390.1|go:"GO:0006412"(translation)|go:"GO:0007568"(aging)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0043022"(ribosome binding)|go:"GO:0043558"(regulation of translational initiation in response to stress)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0044207"(translation initiation ternary complex)|go:"GO:0045202"(synapse)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0097451"(glial limiting end-foot)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|interpro:IPR003029(S1, RNA binding)|interpro:IPR011488(Eukaryotic translation initiation factor 2, alpha subunit)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR024054|interpro:IPR024055|interpro:IPR044126|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731|go:"GO:0005851"(eukaryotic translation initiation factor 2B complex)|ensembl:ENSMUSG00000021116(gene)|ensembl:ENSMUST00000071230(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:FKeyVi3QK42ZWZl8m/PyPoleIDQ10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q3ULD5	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-6877475|ensembl:ENSMUSP00000022148|uniprotkb:Q3UPS6	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:mccb_mouse(display_long)|uniprotkb:Mccc2(gene name)|psi-mi:Mccc2(display_short)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000021646(gene)|ensembl:ENSMUST00000022148(transcript)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q3ULD5|reactome:R-MMU-196780|reactome:R-MMU-70895|refseq:NP_084302.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:0q4wsAWb+zqTRNjZnCPoNabUrbA10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q99L45	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2527165|uniprotkb:Q9CSH6|uniprotkb:Q9CT12|ensembl:ENSMUSP00000096777|ensembl:ENSMUSP00000128257	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:if2b_mouse(display_long)|uniprotkb:Eif2s2(gene name)|psi-mi:Eif2s2(display_short)|uniprotkb:Eukaryotic translation initiation factor 2 subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_080306.1|ensembl:ENSMUSG00000074656(gene)|ensembl:ENSMUST00000099173(transcript)|ensembl:ENSMUST00000166171(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002176"(male germ cell proliferation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0008584"(male gonad development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:Q99L45|reactome:R-MMU-156827|reactome:R-MMU-381042|reactome:R-MMU-382556|reactome:R-MMU-72649|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-72731	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:rFKfeTTSJtJOwP6jsL1OCSQKsCU10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:O55131	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-772161	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:sept7_mouse(display_long)|uniprotkb:Septin7(gene name)|psi-mi:Septin7(display_short)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:Cdc10(gene name synonym)|uniprotkb:Sept7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001192296.1|interpro:IPR016491(Septin)|interpro:IPR008115(Septin 7)|interpro:IPR030379|interpro:IPR027417|mint:O55131|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030496"(midbody)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031105"(septin complex)|go:"GO:0031270"(pseudopodium retraction)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032160"(septin filament array)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048668"(collateral sprouting)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|reactome:R-MMU-5687128	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:VULb4UyoWVn5vRWIzERa9YQJIYo10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q00623	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-1634106|uniprotkb:Q8BPD5|uniprotkb:O08855|uniprotkb:O09042|ensembl:ENSMUSP00000034588	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:apoa1_mouse(display_long)|uniprotkb:Apoa1(gene name)|psi-mi:Apoa1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_033822.2|ensembl:ENSMUSG00000032083(gene)|ensembl:ENSMUST00000034588(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0071813"(lipoprotein particle binding)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:Q00623|rcsb pdb:2LEM|reactome:R-MMU-114608|reactome:R-MMU-1369062|reactome:R-MMU-2168880|reactome:R-MMU-3000471|reactome:R-MMU-3000480|reactome:R-MMU-381426|reactome:R-MMU-8957275|reactome:R-MMU-8963888|reactome:R-MMU-8963896|reactome:R-MMU-8963901|reactome:R-MMU-8964011|reactome:R-MMU-8964058|reactome:R-MMU-9707616|reactome:R-MMU-975634	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:RFvdsVcof99jM6K/bEi1N1Vn9hE10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P80315	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-772370|ensembl:ENSMUSP00000133523	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:tcpd_mouse(display_long)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:A45(gene name synonym)|uniprotkb:Cct4(gene name)|psi-mi:Cct4(display_short)|uniprotkb:Cctd(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_033967.1|ensembl:ENSMUSG00000007739(gene)|ensembl:ENSMUST00000173867(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80315|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:/40BY5vhE/fuloWu9L2k7ujy9Nc10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q8BKZ9	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-6877565|ensembl:ENSMUSP00000011058	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:odpx_mouse(display_long)|uniprotkb:Pdhx(gene name)|psi-mi:Pdhx(display_short)|uniprotkb:Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Lipoyl-containing pyruvate dehydrogenase complex component X(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000010914(gene)|ensembl:ENSMUST00000011058(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:Q8BKZ9|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268|refseq:NP_780303.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:5b1n89M4YLpENMk4kqCsO2oQqJ010090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P97376	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-5692339|uniprotkb:Q99M42|ensembl:ENSMUSP00000033999	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:frg1_mouse(display_long)|uniprotkb:Frg1(gene name)|psi-mi:Frg1(display_short)|uniprotkb:FSHD region gene 1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_038550.2|refseq:XP_017168059.1|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0007517"(muscle organ development)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0030018"(Z disc)|go:"GO:0051015"(actin filament binding)|go:"GO:0055120"(striated muscle dense body)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010414(FRG1-like)|rcsb pdb:2YUG|ensembl:ENSMUSG00000031590(gene)|ensembl:ENSMUST00000033999(transcript)	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:/MMx1dXxEmlGynDkKwB9E86nOzw10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q922Q8	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-647863|uniprotkb:Q3TJ35|uniprotkb:Q3TLC7|uniprotkb:Q3TWT9|uniprotkb:Q3TX86|ensembl:ENSMUSP00000021239	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:lrc59_mouse(display_long)|uniprotkb:Lrrc59(gene name)|psi-mi:Lrrc59(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_598568.1|ensembl:ENSMUSG00000020869(gene)|ensembl:ENSMUST00000021239(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q922Q8	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:Y2nzjMFwQhLMP697NokEz+jOLUM10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q61656	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-643076|uniprotkb:E9Q105	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ddx5_mouse(display_long)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:RNA helicase p68(gene name synonym)|uniprotkb:DEAD box RNA helicase DEAD1(gene name synonym)|uniprotkb:Ddx5(gene name)|psi-mi:Ddx5(display_short)|uniprotkb:Tnz2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|reactome:R-MMU-3899300|reactome:R-MMU-72163|reactome:R-MMU-9018519|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009299"(mRNA transcription)|go:"GO:0019899"(enzyme binding)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035500"(MH2 domain binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061614"(miRNA transcription)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|dip:DIP-32293N|mint:Q61656	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:X5OQN/Gdq852njTrHnlDliAjrQY10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P23116	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2552342|uniprotkb:E9QQ50|ensembl:ENSMUSP00000025955|uniprotkb:Q62162|uniprotkb:Q60697	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:eif3a_mouse(display_long)|uniprotkb:Eif3a(gene name)|psi-mi:Eif3a(display_short)|uniprotkb:Csma(gene name synonym)|uniprotkb:Eif3(gene name synonym)|uniprotkb:Eif3s10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)|uniprotkb:p162(gene name synonym)|uniprotkb:Centrosomin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000024991(gene)|ensembl:ENSMUST00000025955(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:P23116|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|go:"GO:0014069"(postsynaptic density)|refseq:NP_034253.3	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:oL2Xlz5tghN0YkjvCd3nXOj15Hk10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q60597	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-773541|uniprotkb:Q3UDM7|uniprotkb:Q5DTI4|uniprotkb:Q5SVX7|uniprotkb:Q5SVX9|uniprotkb:Q6PFZ2|uniprotkb:Q80Y57|uniprotkb:Q8K0K7|uniprotkb:Q8K2Z3|uniprotkb:Q8R3M2|uniprotkb:Q91WP2|ensembl:ENSMUSP00000003461|ensembl:ENSMUSP00000099090	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:odo1_mouse(display_long)|uniprotkb:Alpha-ketoglutarate dehydrogenase(gene name synonym)|uniprotkb:Ogdh(gene name)|psi-mi:Ogdh(display_short)|uniprotkb:Kiaa4192(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_035086.2|refseq:XP_006514645.1|refseq:XP_006514646.1|refseq:XP_006514647.1|refseq:XP_006514648.1|refseq:NP_001239211.1|refseq:NP_001239212.1|refseq:NP_001239216.1|refseq:NP_001239217.1|refseq:XP_017169826.1|ensembl:ENSMUSG00000020456(gene)|ensembl:ENSMUST00000003461(transcript)|ensembl:ENSMUST00000101554(transcript)|go:"GO:0004591"("oxoglutarate dehydrogenase (succinyl-transferring) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006096"(glycolytic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0022028"(tangential migration from the subventricular zone to the olfactory bulb)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034602"("oxoglutarate dehydrogenase (NAD+) activity")|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061034"(olfactory bulb mitral cell layer development)|go:"GO:0106077"(histone succinylation)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR005475(Transketolase, central region)|interpro:IPR011603(2-oxoglutarate dehydrogenase, E1 component)|interpro:IPR029061|interpro:IPR031717|interpro:IPR032106|interpro:IPR042179|mint:Q60597|rcsb pdb:3E2H|rcsb pdb:3TF7|reactome:R-MMU-389661|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:6as/Sp5FTXpjU1BwjR7vJ6xcxuA10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q76MZ3	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-400413|ensembl:ENSMUSP00000007708	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:2aaa_mouse(display_long)|uniprotkb:Ppp2r1a(gene name)|psi-mi:Ppp2r1a(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_058587.1|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:Q76MZ3|rcsb pdb:2IAE|rcsb pdb:2PF4|rcsb pdb:3FGA|rcsb pdb:6EF4|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2995383|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-8854518|reactome:R-MMU-9648025|reactome:R-MMU-975957|ensembl:ENSMUSG00000007564(gene)|ensembl:ENSMUST00000007708(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051232"(meiotic spindle elongation)|dip:DIP-29429N	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:0tnO11U1SNOOT46j23f7dim8O8k10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P14131	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-4286141|uniprotkb:Q3THM9|ensembl:ENSMUSP00000103940	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:rs16_mouse(display_long)|uniprotkb:Rps16(gene name)|psi-mi:Rps16(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_038675.2|ensembl:ENSMUSG00000037563(gene)|ensembl:ENSMUST00000082134(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P14131|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|reactome:R-MMU-72649	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:OrKriR6HsATLaO+drdUa2w3Gpd010090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:O35857	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-20566939|ensembl:ENSMUSP00000003029|uniprotkb:Q2NLC5	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:tim44_mouse(display_long)|uniprotkb:Timm44(gene name)|psi-mi:Timm44(display_short)|uniprotkb:Mimt44(gene name synonym)|uniprotkb:Tim44(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000002949(gene)|ensembl:ENSMUST00000003029(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0051087"(chaperone binding)|interpro:IPR007379(Mitochondrial import inner membrane translocase, subunit Tim44)|interpro:IPR017303(Import inner membrane translocase, TIM44 subunit, mitochondria)|interpro:IPR032710|interpro:IPR039544|refseq:NP_035722.2	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:HqaSsTG5XA4EAHWJyqhBfq1Eyns10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9CQ62	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-299499|ensembl:ENSMUSP00000029877|uniprotkb:Q9DCI7	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:decr_mouse(display_long)|uniprotkb:Decr1(gene name)|psi-mi:Decr1(display_short)|uniprotkb:2,4-dienoyl-CoA reductase [NADPH](gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000028223(gene)|ensembl:ENSMUST00000029877(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0008670"("2,4-dienoyl-CoA reductase (NADPH) activity")|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902494"(catalytic complex)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q9CQ62|reactome:R-MMU-77288|go:"GO:0042802"(identical protein binding)|go:"GO:0070402"(NADPH binding)|refseq:NP_080448.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:Bh2PIoAhcHP1Sek3ELKceJj2xF410090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9EQP2	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-491022|ensembl:ENSMUSP00000028755	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ehd4_mouse(display_long)|uniprotkb:Ehd4(gene name)|psi-mi:Ehd4(display_short)|uniprotkb:Past2(gene name synonym)|uniprotkb:PAST homolog 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_598599.2|ensembl:ENSMUSG00000027293(gene)|ensembl:ENSMUST00000028755(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|interpro:IPR031692|interpro:IPR040990|mint:Q9EQP2|rcsb pdb:5MTV|rcsb pdb:5MVF|interpro:IPR030381|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:Amxin/3NzINpV4SP1xvRjstQAG010090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q91VA7	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-773408|ensembl:ENSMUSP00000028892	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:q91va7_mouse(display_long)|uniprotkb:Idh3b(gene name)|psi-mi:Idh3b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_570954.1|ensembl:ENSMUSG00000027406(gene)|ensembl:ENSMUST00000028892(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q91VA7|reactome:R-MMU-71403	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:d7ckzD+a/x+uD5i8Sx1YHO8FQGY10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q91YR7	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-6876849|ensembl:ENSMUSP00000002529|ensembl:ENSMUSP00000121340|uniprotkb:Q3ULJ7|uniprotkb:Q542P0|uniprotkb:Q8CIK9|uniprotkb:Q8R3M8|uniprotkb:Q99JN1|uniprotkb:Q9CSZ0	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:prp6_mouse(display_long)|uniprotkb:Prpf6(gene name)|psi-mi:Prpf6(display_short)|uniprotkb:PRP6 homolog(gene name synonym)|uniprotkb:U5 snRNP-associated 102 kDa protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000002455(gene)|ensembl:ENSMUST00000002529(transcript)|ensembl:ENSMUST00000136481(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005682"(U5 snRNP)|go:"GO:0006403"(RNA localization)|go:"GO:0016607"(nuclear speck)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR010491(PRP1 splicing factor, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR027108|mint:Q91YR7|rcsb pdb:6QX9|reactome:R-MMU-72163|reactome:R-MMU-72165|refseq:NP_598462.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:dxGQPYKGfgDyylKz6TISBJfMIBs10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P84089	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2551866|ensembl:ENSMUSP00000021559|ensembl:ENSMUSP00000147411|uniprotkb:Q14259|uniprotkb:P70659	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:erh_mouse(display_long)|uniprotkb:Erh(gene name)|psi-mi:Erh(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000021131(gene)|ensembl:ENSMUSG00000063412(gene)|ensembl:ENSMUST00000021559(transcript)|ensembl:ENSMUST00000080152(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84089|rcsb pdb:1WWQ|rcsb pdb:1WZ7|refseq:NP_031977.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:O70194	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-773893|uniprotkb:Q8BLH0|uniprotkb:Q8BWW1|ensembl:ENSMUSP00000098053	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:eif3d_mouse(display_long)|uniprotkb:Eif3s7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym)|uniprotkb:Eif3d(gene name)|psi-mi:Eif3d(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_061219.2|refseq:XP_006521255.1|ensembl:ENSMUSG00000016554(gene)|ensembl:ENSMUST00000100484(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O70194|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:3AScEAsTKzZ+lSa6oU8pPy6UxgM10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q8BGH2	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2934811|ensembl:ENSMUSP00000023071|uniprotkb:Q3TIL3|uniprotkb:Q3TTG7|uniprotkb:Q3TWD3	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:sam50_mouse(display_long)|uniprotkb:Samm50(gene name)|psi-mi:Samm50(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	ensembl:ENSMUSG00000022437(gene)|ensembl:ENSMUST00000023071(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0042407"(cristae formation)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|mint:Q8BGH2|reactome:R-MMU-9013404|refseq:NP_848729.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:OWxecVBGU7/ayT7jqSrqeKmr5fw10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P27659	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2526690|uniprotkb:O89071|uniprotkb:Q91VJ6|ensembl:ENSMUSP00000080354	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:rl3_mouse(display_long)|uniprotkb:Rpl3(gene name)|psi-mi:Rpl3(display_short)|uniprotkb:J1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_038790.2|ensembl:ENSMUSG00000060036(gene)|ensembl:ENSMUST00000081650(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P27659|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:GrC8OWBLXBaBuOrzEOvyR6cid1A10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:O08553	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9CQE8	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-912160|ensembl:ENSMUSP00000022341	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:rtraf_mouse(display_long)|uniprotkb:RTRAF(gene name)|psi-mi:RTRAF(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_080804.1|ensembl:ENSMUSG00000021807(gene)|ensembl:ENSMUST00000022341(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:0072686"(mitotic spindle)|interpro:IPR019265|mint:Q9CQE8	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:AP73IJnWMs4jwKTGnIC+q1GcBRc10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9QYC0	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-774264|uniprotkb:Q9JLE3|ensembl:ENSMUSP00000109979	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:adda_mouse(display_long)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym)|uniprotkb:Add1(gene name)|psi-mi:Add1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001318009.1|refseq:NP_001318016.1|refseq:NP_001019629.2|refseq:NP_038485.1|refseq:XP_017176104.1|refseq:NP_001095914.1|ensembl:ENSMUSG00000029106(gene)|ensembl:ENSMUST00000114340(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1903142"(positive regulation of establishment of endothelial barrier)|go:"GO:1903393"(positive regulation of adherens junction organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR027766|interpro:IPR036409|mint:Q9QYC0|reactome:R-MMU-264870|reactome:R-MMU-5223345	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:Z5ZTggQNVfhxzdHaJH8OaQC0FXk10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9D0K2	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-645913|uniprotkb:Q9CV92|uniprotkb:Q3TIW6|ensembl:ENSMUSP00000106318	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:scot1_mouse(display_long)|uniprotkb:"Somatic-type succinyl-CoA:3-oxoacid CoA-transferase"(gene name synonym)|uniprotkb:Oxct1(gene name)|psi-mi:Oxct1(display_short)|uniprotkb:Oxct(gene name synonym)|uniprotkb:Scot(gene name synonym)|uniprotkb:3-oxoacid CoA-transferase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_077150.1|interpro:IPR004163(Coenzyme A transferase binding site)|interpro:IPR004164(Coenzyme A transferase active site)|interpro:IPR004165(Coenzyme A transferase)|interpro:IPR012791(3-oxoacid CoA-transferase, subunit B)|interpro:IPR012792(3-oxoacid CoA-transferase, subunit A)|interpro:IPR014388(3-oxoacid CoA-transferase)|interpro:IPR037171|mint:Q9D0K2|reactome:R-MMU-77108|ensembl:ENSMUST00000110690(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008260"(3-oxoacid CoA-transferase activity)|go:"GO:0008410"(CoA-transferase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0014823"(response to activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042182"(ketone catabolic process)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0046950"(cellular ketone body metabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|ensembl:ENSMUSG00000022186(gene)	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:KSJpQdbufFtI07fqqPLQdJrkT2I10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q62351	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-3869520|uniprotkb:Q61560|ensembl:ENSMUSP00000023486	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:tfr1_mouse(display_long)|uniprotkb:Tfrc(gene name)|psi-mi:Tfrc(display_short)|uniprotkb:Trfr(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_035768.1|refseq:XP_006522062.1|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051087"(chaperone binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR003137(Protease-associated PA)|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR029513|interpro:IPR036757|interpro:IPR037324|interpro:IPR039373|mint:Q62351|reactome:R-MMU-432722|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-8980692|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-917977|reactome:R-MMU-9696270|reactome:R-MMU-9696273|ensembl:ENSMUSG00000022797(gene)|ensembl:ENSMUST00000023486(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004998"(transferrin receptor activity)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033572"(transferrin transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:VFnVdK5loK3683nCBW7vxIe7M6Y10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9QYJ0	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-772431|ensembl:ENSMUSP00000034138	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:dnja2_mouse(display_long)|uniprotkb:Dnaja2(gene name)|psi-mi:Dnaja2(display_short)|uniprotkb:mDj3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_062768.1|ensembl:ENSMUSG00000031701(gene)|ensembl:ENSMUST00000034138(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:Q9QYJ0|reactome:R-MMU-3371497	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:ZYn3t1WpFrPa82gsMHxjaQRPr3k10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P70404	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-773416|ensembl:ENSMUSP00000056502	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:idhg1_mouse(display_long)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)|uniprotkb:Idh3g(gene name)|psi-mi:Idh3g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_032349.1|ensembl:ENSMUSG00000002010(gene)|ensembl:ENSMUST00000052761(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P70404|reactome:R-MMU-71403	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:0wCp92dH0hTrNyYmucC9Ob73aBU10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:P27546	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-2526714|uniprotkb:Q05BJ2|uniprotkb:Q3UIS2|uniprotkb:Q3UUH5|uniprotkb:Q3UY36|uniprotkb:Q7TPC6|uniprotkb:Q7TPD4|uniprotkb:Q80YQ5|uniprotkb:Q8CFP5|ensembl:ENSMUSP00000035055	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:map4_mouse(display_long)|uniprotkb:Map4(gene name)|psi-mi:Map4(display_short)|uniprotkb:Mtap4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	refseq:NP_001192259.1|refseq:NP_001192261.1|refseq:NP_032659.2|ensembl:ENSMUSG00000032479(gene)|ensembl:ENSMUST00000035055(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27546|go:"GO:0043005"(neuron projection)|refseq:NP_001298092.1|refseq:NP_001298093.1|refseq:XP_017168653.1	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:DVblnhNfUaxX6rpvxn660Pq09L410090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P14094	uniprotkb:Q9D8N0	intact:EBI-770851|ensembl:ENSMUSP00000027863	intact:EBI-773880|uniprotkb:Q920C5|uniprotkb:Q9CRT5|uniprotkb:Q9CSU3|uniprotkb:Q9D004|ensembl:ENSMUSP00000093955	psi-mi:at1b1_mouse(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Atp4b(gene name synonym)	psi-mi:ef1g_mouse(display_long)|uniprotkb:eEF-1B gamma(gene name synonym)|uniprotkb:Eef1g(gene name)|psi-mi:Eef1g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20566937|imex:IM-26422-9	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033851.1|ensembl:ENSMUSG00000026576(gene)|ensembl:ENSMUST00000027863(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0043209"(myelin sheath)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P14094|reactome:R-MMU-210991|reactome:R-MMU-5578775|reactome:R-MMU-936837	go:"GO:0003746"(translation elongation factor activity)|dip:DIP-32124N|refseq:NP_080283.3|ensembl:ENSMUSG00000071644(gene)|ensembl:ENSMUST00000052248(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:Q9D8N0|reactome:R-MMU-156842	-	-	-	figure legend:Table S10|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:KbjR6KnylxxJPBAUGpOd2RpxAfE10090	rogid:TsONpdlsFR2YmfxQmAH4ByI5/Bg10090	rigid:oVly1pZHAN5Cb8KOY/y57OwT3po	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:P08032	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-8350116|uniprotkb:B2RWX6|intact:MINT-85326|uniprotkb:P97502|ensembl:ENSMUSP00000027817	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:spta1_mouse(display_long)|uniprotkb:Spta1(gene name)|psi-mi:Spta1(display_short)|uniprotkb:Spna1(gene name synonym)|uniprotkb:Spta(gene name synonym)|uniprotkb:Erythroid alpha-spectrin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_035595.2|ensembl:ENSMUSG00000026532(gene)|ensembl:ENSMUST00000027817(transcript)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036028|mint:P08032|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	comment:mint|function:Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:uaswmTQnd1d+MrnYyCICUC3vTkM10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q9D8N0	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-773880|uniprotkb:Q920C5|uniprotkb:Q9CRT5|uniprotkb:Q9CSU3|uniprotkb:Q9D004|ensembl:ENSMUSP00000093955	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:ef1g_mouse(display_long)|uniprotkb:eEF-1B gamma(gene name synonym)|uniprotkb:Eef1g(gene name)|psi-mi:Eef1g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	go:"GO:0003746"(translation elongation factor activity)|dip:DIP-32124N|refseq:NP_080283.3|ensembl:ENSMUSG00000071644(gene)|ensembl:ENSMUST00000052248(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:Q9D8N0|reactome:R-MMU-156842	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:TsONpdlsFR2YmfxQmAH4ByI5/Bg10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q9Z1Q9	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-6123642|uniprotkb:Q9QUN2|ensembl:ENSMUSP00000084572	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:syvc_mouse(display_long)|uniprotkb:Vars1(gene name)|psi-mi:Vars1(display_short)|uniprotkb:Bat6(gene name synonym)|uniprotkb:G7a(gene name synonym)|uniprotkb:Protein G7a(gene name synonym)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)|uniprotkb:Vars(gene name synonym)|uniprotkb:Vars2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_035820.3|refseq:XP_017172884.1|ensembl:ENSMUSG00000007029(gene)|ensembl:ENSMUST00000087315(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004832"(valine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006438"(valyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033705|interpro:IPR036282|interpro:IPR037118|mint:Q9Z1Q9	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:gAbY8qZ5vHpLxCj9zbBarjEd1hk10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q9JHU4	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-645061|uniprotkb:E9QM71|ensembl:ENSMUSP00000018851	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:dyhc1_mouse(display_long)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_084514.2|ensembl:ENSMUSG00000018707(gene)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0003341"(cilium movement)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|ensembl:ENSMUST00000018851(transcript)|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR042219|mint:Q9JHU4|rcsb pdb:3ERR|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3WUQ|rcsb pdb:5AYH|rcsb pdb:6RZA|rcsb pdb:6RZB|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:sbED0xqQpe32T7I8ijeS3Xqlx7010090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q9QXS1	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-774583|uniprotkb:Q9QXR8|uniprotkb:Q9QXR9|uniprotkb:Q6S384|uniprotkb:Q6S389|uniprotkb:Q6S394|uniprotkb:Q9CS65|uniprotkb:Q9QUT2|uniprotkb:Q9QXQ8|uniprotkb:Q9QXQ9|uniprotkb:Q9QXR0|uniprotkb:Q9QXR1|uniprotkb:Q9QXR2|uniprotkb:Q9QXR3|uniprotkb:Q9QXR4|uniprotkb:Q9QXR5|uniprotkb:Q9QXR6|uniprotkb:Q9QXR7|uniprotkb:Q9QXS0|uniprotkb:Q9QXS2|uniprotkb:Q9QXS3|uniprotkb:E9QN87|ensembl:ENSMUSP00000073124	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:plec_mouse(display_long)|uniprotkb:Plectin-6(gene name synonym)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_001157012.1|refseq:NP_001157014.1|refseq:NP_001157021.1|refseq:NP_001157675.1|refseq:NP_035247.2|refseq:NP_958791.2|refseq:NP_958796.2|dip:DIP-32004N|ensembl:ENSMUSG00000022565(gene)|ensembl:ENSMUST00000073418(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0043588"(skin development)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071944"(cell periphery)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR018159|interpro:IPR030269|interpro:IPR035915|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q9QXS1|rcsb pdb:1SH5|rcsb pdb:1SH6|rcsb pdb:4Q57|reactome:R-MMU-264870|reactome:R-MMU-446107	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:9cGCRGhjImLIGd9shNPJRdSpdoY10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q3TTY5	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-2943256|ensembl:ENSMUSP00000023712|uniprotkb:Q0VBW1|uniprotkb:Q61869	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:k22e_mouse(display_long)|uniprotkb:Krt2(gene name)|psi-mi:Krt2(display_short)|uniprotkb:K2e(gene name synonym)|uniprotkb:Krt2-17(gene name synonym)|uniprotkb:Krt2a(gene name synonym)|uniprotkb:Cytokeratin-2e(gene name synonym)|uniprotkb:Epithelial keratin-2e(gene name synonym)|uniprotkb:Keratin-2 epidermis(gene name synonym)|uniprotkb:Keratin-2e(gene name synonym)|uniprotkb:Type-II keratin Kb2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	ensembl:ENSMUSG00000064201(gene)|ensembl:ENSMUST00000023712(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003334"(keratinocyte development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|go:"GO:0032980"(keratinocyte activation)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0045095"(keratin filament)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045684"(positive regulation of epidermis development)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|reactome:R-MMU-6805567|reactome:R-MMU-6809371|go:"GO:0051546"(keratinocyte migration)|refseq:NP_034798.2	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:UwZwFmRjZoxqQdGakNutPZXeKIE10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q9D051	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-773622|uniprotkb:Q3TL86|uniprotkb:Q505N8|uniprotkb:Q99LW9|ensembl:ENSMUSP00000022268	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:odpb_mouse(display_long)|uniprotkb:Pdhb(gene name)|psi-mi:Pdhb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_077183.1|ensembl:ENSMUSG00000021748(gene)|ensembl:ENSMUST00000022268(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:Q9D051|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:FPts4odLhVgLVf3gEYdc9N5Wuak10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:P14206	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:P62806	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-299632|ensembl:ENSMUSP00000085006|ensembl:ENSMUSP00000100029|ensembl:ENSMUSP00000100030|ensembl:ENSMUSP00000100032|ensembl:ENSMUSP00000100033|ensembl:ENSMUSP00000100036|ensembl:ENSMUSP00000100037|ensembl:ENSMUSP00000100042|ensembl:ENSMUSP00000100044|ensembl:ENSMUSP00000100048|ensembl:ENSMUSP00000100546|ensembl:ENSMUSP00000129930|ensembl:ENSMUSP00000136357|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q2M2Q5|intact:EBI-302111|uniprotkb:Q6PDS7|uniprotkb:Q811M0|uniprotkb:A0AUM5|uniprotkb:A4FUP8|uniprotkb:A4QMY0|uniprotkb:Q0VDL9|uniprotkb:Q9D0C9|uniprotkb:Q9D6Q8|uniprotkb:Q5T006	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:h4_mouse(display_long)|uniprotkb:H4c11(gene name)|psi-mi:H4c11(display_short)|uniprotkb:H4c12(gene name)|psi-mi:H4c12(display_short)|uniprotkb:H4c14(gene name)|psi-mi:H4c14(display_short)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4c3(gene name)|psi-mi:H4c3(display_short)|uniprotkb:H4c4(gene name)|psi-mi:H4c4(display_short)|uniprotkb:H4c6(gene name)|psi-mi:H4c6(display_short)|uniprotkb:H4c8(gene name)|psi-mi:H4c8(display_short)|uniprotkb:H4c9(gene name)|psi-mi:H4c9(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist1h4a(gene name synonym)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist1h4c(gene name synonym)|uniprotkb:Hist1h4d(gene name synonym)|uniprotkb:Hist1h4f(gene name synonym)|uniprotkb:Hist1h4h(gene name synonym)|uniprotkb:Hist1h4i(gene name synonym)|uniprotkb:Hist1h4j(gene name synonym)|uniprotkb:Hist1h4k(gene name synonym)|uniprotkb:Hist2h4a(gene name synonym)|uniprotkb:Hist2h4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4-53(gene name synonym)|uniprotkb:H4-12(gene name synonym)|uniprotkb:H4c1(gene name)|psi-mi:H4c1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	ensembl:ENSMUSG00000060093(gene)|ensembl:ENSMUSG00000060639(gene)|ensembl:ENSMUSG00000060678(gene)|ensembl:ENSMUSG00000060981(gene)|ensembl:ENSMUSG00000061482(gene)|ensembl:ENSMUSG00000064288(gene)|ensembl:ENSMUSG00000067455(gene)|ensembl:ENSMUSG00000069266(gene)|ensembl:ENSMUSG00000069274(gene)|ensembl:ENSMUSG00000069305(gene)|ensembl:ENSMUSG00000069306(gene)|ensembl:ENSMUSG00000091405(gene)|ensembl:ENSMUST00000087714(transcript)|ensembl:ENSMUST00000102964(transcript)|ensembl:ENSMUST00000102965(transcript)|ensembl:ENSMUST00000102967(transcript)|ensembl:ENSMUST00000102968(transcript)|ensembl:ENSMUST00000102971(transcript)|ensembl:ENSMUST00000102972(transcript)|ensembl:ENSMUST00000102977(transcript)|ensembl:ENSMUST00000102979(transcript)|ensembl:ENSMUST00000102983(transcript)|ensembl:ENSMUST00000104941(transcript)|ensembl:ENSMUST00000171473(transcript)|ensembl:ENSMUST00000179285(transcript)|go:"GO:0000228"(nuclear chromosome)|ensembl:ENSMUSG00000096010(gene)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62806|rcsb pdb:1F66|rcsb pdb:1U35|rcsb pdb:2WP2|go:"GO:0003677"(DNA binding)|rcsb pdb:4AU7|rcsb pdb:4DOW|rcsb pdb:5B1L|rcsb pdb:5B1M|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-110331|reactome:R-MMU-212300|reactome:R-MMU-2299718|reactome:R-MMU-2559580|reactome:R-MMU-110330|reactome:R-MMU-2559582|reactome:R-MMU-2559586|reactome:R-MMU-3214815|reactome:R-MMU-3214841|reactome:R-MMU-3214842|reactome:R-MMU-3214847|reactome:R-MMU-3214858|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-4551638|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-5693565|reactome:R-MMU-5693571|reactome:R-MMU-5693607|reactome:R-MMU-606279|reactome:R-MMU-69473|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-8936459|reactome:R-MMU-9018519|reactome:R-MMU-9670095|refseq:NP_001182350.1|refseq:NP_291074.1|refseq:NP_694813.1|refseq:NP_783583.1|refseq:NP_783585.1|refseq:NP_783586.1|refseq:NP_783587.1|refseq:NP_783588.1|refseq:NP_835499.1|refseq:NP_835500.1|refseq:NP_835515.1|refseq:NP_835582.1|refseq:NP_835583.1|dip:DIP-45837N	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q8BMF4	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-769141|uniprotkb:Q8K2G8|uniprotkb:Q8R339|uniprotkb:Q91ZB1|ensembl:ENSMUSP00000034567	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:odp2_mouse(display_long)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:Dlat(gene name)|psi-mi:Dlat(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_663589.3|ensembl:ENSMUSG00000000168(gene)|ensembl:ENSMUST00000034567(transcript)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030431"(sleep)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:Q8BMF4|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:I0x+9L5a4O6Bch+NFbNzYiONj+810090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:P53395	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-773148|uniprotkb:Q3TMF5|ensembl:ENSMUSP00000000349	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:odb2_mouse(display_long)|uniprotkb:"Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase"(gene name synonym)|uniprotkb:Dihydrolipoamide branched chain transacylase(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex(gene name synonym)|uniprotkb:Dbt(gene name)|psi-mi:Dbt(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_034152.2|ensembl:ENSMUSG00000000340(gene)|ensembl:ENSMUST00000000349(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0031405"(lipoic acid binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043754"("dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity")|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P53395|reactome:R-MMU-389661|reactome:R-MMU-70895|reactome:R-MMU-9013407	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:/g3DD7tq0CE5mqTJD4ZifLuIy5E10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q7TMM9	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-2255578|ensembl:ENSMUSP00000060246	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:tbb2a_mouse(display_long)|uniprotkb:Tubb2(gene name synonym)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_033476.1|ensembl:ENSMUSG00000058672(gene)|ensembl:ENSMUST00000056427(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q7TMM9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:P26039	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-1039593|uniprotkb:Q8VEF0|uniprotkb:A2AIM8|ensembl:ENSMUSP00000030187	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:tln1_mouse(display_long)|uniprotkb:Tln1(gene name)|psi-mi:Tln1(display_short)|uniprotkb:Tln(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_035732.2|refseq:XP_006537832.2|ensembl:ENSMUSG00000028465(gene)|ensembl:ENSMUST00000030187(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:P26039|rcsb pdb:1SJ7|rcsb pdb:1SJ8|rcsb pdb:1T01|rcsb pdb:1U89|rcsb pdb:1XWX|rcsb pdb:1Y19|rcsb pdb:1ZW3|rcsb pdb:2B0H|rcsb pdb:2G35|rcsb pdb:2JSW|rcsb pdb:2KBB|rcsb pdb:2KC1|rcsb pdb:2KC2|rcsb pdb:2KGX|rcsb pdb:2KMA|rcsb pdb:2KVP|rcsb pdb:2L10|rcsb pdb:2L7A|rcsb pdb:2L7N|rcsb pdb:2LQG|rcsb pdb:2QDQ|rcsb pdb:2X0C|rcsb pdb:3DYJ|rcsb pdb:3IVF|rcsb pdb:3S90|rcsb pdb:4F7G|rcsb pdb:4W8P|rcsb pdb:5FZT|rcsb pdb:5IC0|rcsb pdb:5IC1|rcsb pdb:5NL1|rcsb pdb:6BA6|rcsb pdb:6MFS|rcsb pdb:6TWN|rcsb pdb:6VGU|reactome:R-MMU-114608|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-399955|reactome:R-MMU-445355|reactome:R-MMU-5674135|dip:DIP-647N	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:w9NQrwqUcuVAzeesymnTmhrEtCk10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:P35486	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-773613|ensembl:ENSMUSP00000033662	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:odpa_mouse(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:Pdha1(gene name)|psi-mi:Pdha1(display_short)|uniprotkb:Pdha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_032836.1|ensembl:ENSMUSG00000031299(gene)|ensembl:ENSMUST00000033662(transcript)|go:"GO:0004738"(pyruvate dehydrogenase activity)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0043209"(myelin sheath)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|interpro:IPR029061|mint:P35486|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:QIfCMikb5tVYwefUZs3+5ut/nbY10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:O08807	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-494652|uniprotkb:Q3U8E4|uniprotkb:B1AZS7|ensembl:ENSMUSP00000026328	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:prdx4_mouse(display_long)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)|uniprotkb:Prdx4(gene name)|psi-mi:Prdx4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_058044.1|refseq:NP_001300640.1|dip:DIP-34137N|ensembl:ENSMUSG00000025289(gene)|ensembl:ENSMUST00000026328(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:O08807|rcsb pdb:3VWU|rcsb pdb:3VWV|rcsb pdb:3W8J|rcsb pdb:3WGX|reactome:R-MMU-6798695	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:86EzEedrO6v5Z2dnSB2fSPaV2hc10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:O55131	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-772161	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:sept7_mouse(display_long)|uniprotkb:Septin7(gene name)|psi-mi:Septin7(display_short)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:Cdc10(gene name synonym)|uniprotkb:Sept7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_001192296.1|interpro:IPR016491(Septin)|interpro:IPR008115(Septin 7)|interpro:IPR030379|interpro:IPR027417|mint:O55131|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030496"(midbody)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031105"(septin complex)|go:"GO:0031270"(pseudopodium retraction)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032160"(septin filament array)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048668"(collateral sprouting)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|reactome:R-MMU-5687128	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:VULb4UyoWVn5vRWIzERa9YQJIYo10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q8VIJ6	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-6094576|uniprotkb:A2A7U6|uniprotkb:Q9ERW2|ensembl:ENSMUSP00000030623	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:sfpq_mouse(display_long)|uniprotkb:Sfpq(gene name)|psi-mi:Sfpq(display_short)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:Psf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_076092.1|ensembl:ENSMUSG00000028820(gene)|ensembl:ENSMUST00000030623(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:Q8VIJ6|reactome:R-MMU-8849468	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:9mciNgfKrEvyAv7kjs55FHlUtRY10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q8BKZ9	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-6877565|ensembl:ENSMUSP00000011058	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:odpx_mouse(display_long)|uniprotkb:Pdhx(gene name)|psi-mi:Pdhx(display_short)|uniprotkb:Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Lipoyl-containing pyruvate dehydrogenase complex component X(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	ensembl:ENSMUSG00000010914(gene)|ensembl:ENSMUST00000011058(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:Q8BKZ9|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268|refseq:NP_780303.1	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:5b1n89M4YLpENMk4kqCsO2oQqJ010090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:P62259	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:P08551	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-445199|uniprotkb:Q8K0Z0|ensembl:ENSMUSP00000022639	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:nfl_mouse(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:Nefl(gene name)|psi-mi:Nefl(display_short)|uniprotkb:Nfl(gene name synonym)|uniprotkb:Nf68(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_035040.1|ensembl:ENSMUSG00000022055(gene)|ensembl:ENSMUST00000022639(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P08551|reactome:R-MMU-438066|reactome:R-MMU-5673001|go:"GO:0098981"(cholinergic synapse)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|dip:DIP-31944N	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:E8KK2ppZXyLXIlFZp/pjXv7GBEU10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q8CC88	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-12602574|ensembl:ENSMUSP00000048925|uniprotkb:Q3U4P9|uniprotkb:Q6ZQ94|uniprotkb:Q8CDH8|uniprotkb:Q8VCU3	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:vwa8_mouse(display_long)|uniprotkb:Vwa8(gene name)|psi-mi:Vwa8(display_short)|uniprotkb:Kiaa0564(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	ensembl:ENSMUSG00000058997(gene)|ensembl:ENSMUST00000040990(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR027417|interpro:IPR036465|interpro:IPR039891|mint:Q8CC88|refseq:NP_082182.1|refseq:NP_776119.2	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:JRlZvEqyEowI+W/4vQZy0mZEQk810090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q8VDD5	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-400906|intact:EBI-777674|uniprotkb:Q3UHT9|uniprotkb:Q3UHU4|uniprotkb:Q6KAN6|uniprotkb:Q811I2|ensembl:ENSMUSP00000016771	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:myh9_mouse(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_071855.2|ensembl:ENSMUSG00000022443(gene)|ensembl:ENSMUST00000016771(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q8VDD5|reactome:R-MMU-2029482|reactome:R-MMU-5627123|dip:DIP-29546N	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	caution:This sequence has been withdrawn from Uniprot.|crc64:AAAC0E83A0A4F24A	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:qYfcGuWOF9npzsKD3zXTuLeP9iE10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:O08749	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-773199|uniprotkb:Q3TG55|uniprotkb:Q3U5W5|uniprotkb:Q3UWP7|uniprotkb:Q99LD3|ensembl:ENSMUSP00000106481	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:dldh_mouse(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Dld(gene name)|psi-mi:Dld(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_031887.2|ensembl:ENSMUSG00000020664(gene)|ensembl:ENSMUST00000110857(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043209"(myelin sheath)|go:"GO:0043544"(lipoamide binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:O08749|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-6783984|reactome:R-MMU-70268|reactome:R-MMU-70895|reactome:R-MMU-71064|reactome:R-MMU-71403	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:6j/8rw4lkNMW4Lo5sGoRdDJBk2w10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q557	uniprotkb:Q3U0V1	intact:EBI-688046|ensembl:ENSMUSP00000115062	intact:EBI-4282969|uniprotkb:Q2VPQ6|uniprotkb:Q6P2L2|uniprotkb:E9QKH3|ensembl:ENSMUSP00000007814	psi-mi:desp_mouse(display_long)|uniprotkb:Dsp(gene name)|psi-mi:Dsp(display_short)	psi-mi:fubp2_mouse(display_long)|uniprotkb:Khsrp(gene name)|psi-mi:Khsrp(display_short)|uniprotkb:Fubp2(gene name synonym)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567147|imex:IM-26422-11	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076331.2|ensembl:ENSMUSG00000054889(gene)|ensembl:ENSMUST00000124830(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:E9Q557|reactome:R-MMU-351906|reactome:R-MMU-6798695|reactome:R-MMU-6805567|reactome:R-MMU-6809371|reactome:R-MMU-9696264|reactome:R-MMU-9696273	refseq:NP_034743.3|ensembl:ENSMUSG00000007670(gene)|ensembl:ENSMUST00000007814(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0030425"(dendrite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:2000628"(regulation of miRNA metabolic process)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q3U0V1|reactome:R-MMU-450604	-	comment:AfCS Y2H protein. Translated from nucleotide sequence.|comment:"Similar to DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen) (95%)"	-	figure legend:Table S9|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/05	rogid:AQF1MrZZW8M5RfagBI7P4b3qQPA10090	rogid:snMZYaCxr5k/zzbgZD18vz5RAfs10090	rigid:7dMnYZhew1/7Uuf3zlIIHhTjbzE	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q8R1B4	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-7466674|uniprotkb:Q8R3M7|intact:MINT-4608642|ensembl:ENSMUSP00000032992	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:eif3c_mouse(display_long)|uniprotkb:Eif3c(gene name)|psi-mi:Eif3c(display_short)|uniprotkb:Eif3s8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_666312.1|ensembl:ENSMUSG00000030738(gene)|ensembl:ENSMUST00000032992(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q8R1B4|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:t9Y/py75bSvLshPOxGcfrNASqeI10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q8R1B4	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-7466674|uniprotkb:Q8R3M7|intact:MINT-4608642|ensembl:ENSMUSP00000032992	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:eif3c_mouse(display_long)|uniprotkb:Eif3c(gene name)|psi-mi:Eif3c(display_short)|uniprotkb:Eif3s8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_666312.1|ensembl:ENSMUSG00000030738(gene)|ensembl:ENSMUST00000032992(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q8R1B4|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:t9Y/py75bSvLshPOxGcfrNASqeI10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P08032	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-8350116|uniprotkb:B2RWX6|intact:MINT-85326|uniprotkb:P97502|ensembl:ENSMUSP00000027817	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:spta1_mouse(display_long)|uniprotkb:Spta1(gene name)|psi-mi:Spta1(display_short)|uniprotkb:Spna1(gene name synonym)|uniprotkb:Spta(gene name synonym)|uniprotkb:Erythroid alpha-spectrin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_035595.2|ensembl:ENSMUSG00000026532(gene)|ensembl:ENSMUST00000027817(transcript)|go:"GO:0002260"(lymphocyte homeostasis)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006779"(porphyrin-containing compound biosynthetic process)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0008091"(spectrin)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036028|mint:P08032|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878	-	-	comment:mint|function:Spectrin is the major constituent of the cytoskeletal network underlying the erythrocyte plasma membrane. It associates with band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:uaswmTQnd1d+MrnYyCICUC3vTkM10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q91WK2	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-7466721|intact:MINT-4098428|ensembl:ENSMUSP00000022925	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:eif3h_mouse(display_long)|uniprotkb:Eif3h(gene name)|psi-mi:Eif3h(display_short)|uniprotkb:Eif3s3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_542366.1|ensembl:ENSMUSG00000022312(gene)|ensembl:ENSMUST00000022925(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:Q91WK2|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	comment:mint|function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. Associates with the p170 subunit of EIF3	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:mKyE784VSiEMqBaCyG2Vt9FhynM10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q5SW19	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-8315491|intact:UNK-5482502|intact:MINT-4115908|uniprotkb:Q3U4M5|uniprotkb:Q3V3Q8|intact:UNK-5408909|uniprotkb:Q505Q6|uniprotkb:Q6PAT1|uniprotkb:Q8CHD9|uniprotkb:Q6GQX1|uniprotkb:Q3U014|intact:UNK-5473899|intact:UNK-5429492|uniprotkb:A8Y5E2	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:clu_mouse(display_long)|uniprotkb:Cluh(gene name)|psi-mi:Cluh(display_short)|uniprotkb:Kiaa0664(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0048312"(intracellular distribution of mitochondria)|interpro:IPR033646|interpro:IPR025697|refseq:NP_001074627.1|interpro:IPR027523|interpro:IPR028275|refseq:XP_006534416.1|refseq:XP_006534417.1|mint:Q5SW19|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023231	-	-	comment:"fragmentation type: fragment"|comment:mint	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:hyZPFP7G2ri2LuDUtQ2FgZwOggA10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9Z2W0	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-8376702|intact:MINT-4093364|uniprotkb:Q56A00|ensembl:ENSMUSP00000070821|ensembl:ENSMUSP00000109235|ensembl:ENSMUSP00000139739	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:dnpep_mouse(display_long)|uniprotkb:Dnpep(gene name)|psi-mi:Dnpep(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_058574.3|refseq:NP_001104301.1|refseq:XP_006496468.1|refseq:XP_006496469.1|ensembl:ENSMUSG00000026209(gene)|ensembl:ENSMUST00000066668(transcript)|ensembl:ENSMUST00000113605(transcript)|ensembl:ENSMUST00000187836(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|interpro:IPR001948(Peptidase M18, aminopeptidase I)|interpro:IPR023358|mint:Q9Z2W0	-	-	comment:mint|function:Likely to play an important role in intracellular protein and peptide metabolism	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:AHvJ1/SshqtrnjTRu3C0GbgxnK010090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9JII6	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-8321453|uniprotkb:Q9D0I7|uniprotkb:Q9D016|uniprotkb:Q9CQI5|intact:MINT-1869516|uniprotkb:Q9D0P3|uniprotkb:Q9D012|uniprotkb:Q9CT53|uniprotkb:Q9CQT8|ensembl:ENSMUSP00000030455	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:ak1a1_mouse(display_long)|uniprotkb:Akr1a1(gene name)|psi-mi:Akr1a1(display_short)|uniprotkb:Akr1a4(gene name synonym)|uniprotkb:Aldehyde reductase(gene name synonym)|uniprotkb:"Alcohol dehydrogenase [NADP(+)]"(gene name synonym)|uniprotkb:Glucuronate reductase(gene name synonym)|uniprotkb:Glucuronolactone reductase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_067448.1|ensembl:ENSMUSG00000028692(gene)|ensembl:ENSMUST00000030455(transcript)|go:"GO:0004032"("alditol:NADP+ 1-oxidoreductase activity")|go:"GO:0005829"(cytosol)|go:"GO:0008106"("alcohol dehydrogenase (NADP+) activity")|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019726"("mevaldate reductase (NADPH) activity")|go:"GO:0019853"(L-ascorbic acid biosynthetic process)|go:"GO:0042840"(D-glucuronate catabolic process)|go:"GO:0044597"(daunorubicin metabolic process)|go:"GO:0044598"(doxorubicin metabolic process)|go:"GO:0045202"(synapse)|go:"GO:0046185"(aldehyde catabolic process)|go:"GO:0047655"(allyl-alcohol dehydrogenase activity)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0047939"(L-glucuronate reductase activity)|go:"GO:0047941"(glucuronolactone reductase activity)|go:"GO:0047956"(glycerol dehydrogenase [NADP+] activity)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:1990002"("methylglyoxal reductase (NADPH-dependent, acetol producing)")|interpro:IPR018170|interpro:IPR020471|interpro:IPR023210|interpro:IPR036812|interpro:IPR044481|mint:Q9JII6|rcsb pdb:4GAC|reactome:R-MMU-156590|reactome:R-MMU-5661270	-	-	comment:mint|function:Catalyzes the NADPH-dependent reduction of a variety of aldehydes to their corresponding alcohols	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:kEvFTPRQrhIchD7oVZSNFUCDPho10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9DB20	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-2310823|ensembl:ENSMUSP00000023677	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:atpo_mouse(display_long)|uniprotkb:Atp5po(gene name)|psi-mi:Atp5po(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:Atp5o(gene name synonym)|uniprotkb:D12Wsu28e(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_613063.1|ensembl:ENSMUSG00000022956(gene)|ensembl:ENSMUST00000023677(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903924"(estradiol binding)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:Q9DB20|reactome:R-MMU-163210|reactome:R-MMU-8949613	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:WQ9HGMgjrf/WguX3hRtn4ggL5I810090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q91VM5	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-647431|uniprotkb:O35479|ensembl:ENSMUSP00000048153|ensembl:ENSMUSP00000147384	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:rmxl1_mouse(display_long)|uniprotkb:Rbmxl1(gene name)|psi-mi:Rbmxl1(display_short)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G-like 1(gene name synonym)|uniprotkb:RNA binding motif protein, X chromosome retrogene(gene name synonym)|uniprotkb:Rbmxrt(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:XP_006530838.1|refseq:XP_006530839.1|refseq:NP_001239018.1|refseq:NP_033059.2|ensembl:ENSMUSG00000037070(gene)|ensembl:ENSMUST00000049245(transcript)|ensembl:ENSMUST00000211719(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q91VM5	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:1aPRrfU5gcmzCimlfwuz07A4gyA10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q6IFX3	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-20567247|ensembl:ENSMUSP00000073869|uniprotkb:A0AUL0|uniprotkb:Q3B7Y6	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:k1c40_mouse(display_long)|uniprotkb:Cytokeratin-40(gene name synonym)|uniprotkb:Keratin-40(gene name synonym)|uniprotkb:Type I hair keratin Ka36(gene name synonym)|uniprotkb:Krt40(gene name)|psi-mi:Krt40(display_short)|uniprotkb:Ka36(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000059169(gene)|ensembl:ENSMUST00000074253(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|reactome:R-MMU-6805567|reactome:R-MMU-6809371|refseq:NP_001034755.1	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:qBd44J2YW1CeqDt0xh3NvFvKmOQ10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9JHU4	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-645061|uniprotkb:E9QM71|ensembl:ENSMUSP00000018851	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:dyhc1_mouse(display_long)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_084514.2|ensembl:ENSMUSG00000018707(gene)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0003341"(cilium movement)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|ensembl:ENSMUST00000018851(transcript)|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR042219|mint:Q9JHU4|rcsb pdb:3ERR|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3WUQ|rcsb pdb:5AYH|rcsb pdb:6RZA|rcsb pdb:6RZB|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:sbED0xqQpe32T7I8ijeS3Xqlx7010090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9ERG2	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-911729|ensembl:ENSMUSP00000013130	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:strn3_mouse(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:Strn3(gene name)|psi-mi:Strn3(display_short)|uniprotkb:Gs2na(gene name synonym)|uniprotkb:Sg2na(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000020954(gene)|ensembl:ENSMUST00000013130(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR001680(WD40 repeat)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERG2|refseq:NP_443205.1	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:TdtwkF77kxNiBo0jtPGVLwUlxoI10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P51637	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-298576|ensembl:ENSMUSP00000074922	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:cav3_mouse(display_long)|uniprotkb:Cav3(gene name)|psi-mi:Cav3(display_short)|uniprotkb:M-caveolin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051647"(nucleus localization)|go:"GO:0051896"(regulation of protein kinase B signaling)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0051926"(negative regulation of calcium ion transport)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060299"(negative regulation of sarcomere organization)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060347"(heart trabecula formation)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070836"(caveola assembly)|go:"GO:0071253"(connexin binding)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900825"(regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1900826"(negative regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901019"(regulation of calcium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|ensembl:ENSMUSG00000062694(gene)|ensembl:ENSMUST00000075477(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0014704"(intercalated disc)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030154"(cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0038009"(regulation of signal transduction by receptor internalization)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051394"(regulation of nerve growth factor receptor activity)|interpro:IPR001612(Caveolin)|interpro:IPR018361|interpro:IPR031091|mint:P51637|reactome:R-MMU-445355|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|refseq:NP_031643.1|dip:DIP-31069N	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:K9freRN6XcY4lMheGDyaDgx/ZT010090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9QXS1	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-774583|uniprotkb:Q9QXR8|uniprotkb:Q9QXR9|uniprotkb:Q6S384|uniprotkb:Q6S389|uniprotkb:Q6S394|uniprotkb:Q9CS65|uniprotkb:Q9QUT2|uniprotkb:Q9QXQ8|uniprotkb:Q9QXQ9|uniprotkb:Q9QXR0|uniprotkb:Q9QXR1|uniprotkb:Q9QXR2|uniprotkb:Q9QXR3|uniprotkb:Q9QXR4|uniprotkb:Q9QXR5|uniprotkb:Q9QXR6|uniprotkb:Q9QXR7|uniprotkb:Q9QXS0|uniprotkb:Q9QXS2|uniprotkb:Q9QXS3|uniprotkb:E9QN87|ensembl:ENSMUSP00000073124	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:plec_mouse(display_long)|uniprotkb:Plectin-6(gene name synonym)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_001157012.1|refseq:NP_001157014.1|refseq:NP_001157021.1|refseq:NP_001157675.1|refseq:NP_035247.2|refseq:NP_958791.2|refseq:NP_958796.2|dip:DIP-32004N|ensembl:ENSMUSG00000022565(gene)|ensembl:ENSMUST00000073418(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0043588"(skin development)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071944"(cell periphery)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR018159|interpro:IPR030269|interpro:IPR035915|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q9QXS1|rcsb pdb:1SH5|rcsb pdb:1SH6|rcsb pdb:4Q57|reactome:R-MMU-264870|reactome:R-MMU-446107	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:9cGCRGhjImLIGd9shNPJRdSpdoY10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q71LX4	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-2255655|uniprotkb:E9QM49|uniprotkb:Q8BWK0	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:tln2_mouse(display_long)|uniprotkb:Tln2(gene name)|psi-mi:Tln2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	mint:Q71LX4|refseq:NP_001074711.2|dip:DIP-53098N|go:"GO:0001726"(ruffle)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0045202"(synapse)|go:"GO:0051015"(actin filament binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036723|interpro:IPR037438|rcsb pdb:3G9W|interpro:IPR036476	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:fPA7JK3ca5p+y6dQlF+Srehsd2A10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q8VCM7	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-6252682|ensembl:ENSMUSP00000037018|uniprotkb:Q8WUR3|uniprotkb:Q91ZP0	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:fibg_mouse(display_long)|uniprotkb:Fgg(gene name)|psi-mi:Fgg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000033860(gene)|ensembl:ENSMUST00000048486(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037581|mint:Q8VCM7|reactome:R-MMU-114608|reactome:R-MMU-140875|reactome:R-MMU-216083|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-381426|reactome:R-MMU-5674135|reactome:R-MMU-5686938|reactome:R-MMU-8957275|refseq:NP_598623.1	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:AmOFe/GrPI4CGlyrFHBM1QHxYOk10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9D1G0	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-20567221|ensembl:ENSMUSP00000085862|ensembl:ENSMUSP00000113508|uniprotkb:Q3KQI2|uniprotkb:Q9D645	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:dnsl2_mouse(display_long)|uniprotkb:Deoxyribonuclease I-like 2(gene name synonym)|uniprotkb:Dnase1l2(gene name)|psi-mi:Dnase1l2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000024136(gene)|ensembl:ENSMUST00000088506(transcript)|ensembl:ENSMUST00000119932(transcript)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0001942"(hair follicle development)|go:"GO:0003335"(corneocyte development)|go:"GO:0003677"(DNA binding)|go:"GO:0004530"(deoxyribonuclease I activity)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006308"(DNA catabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR016202(Deoxyribonuclease I-like)|interpro:IPR018057|interpro:IPR033125|interpro:IPR036691|refseq:NP_079994.2	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:7FMouzJ8SXa3ZKggXj7P+8QzC5w10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q7M6Y5	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-16081624|ensembl:ENSMUSP00000039912|uniprotkb:E9QL16|uniprotkb:Q4VA46	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:deup1_mouse(display_long)|uniprotkb:Deup1(gene name)|psi-mi:Deup1(display_short)|uniprotkb:Ccdc67(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 67(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000039977(gene)|ensembl:ENSMUST00000045513(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0030030"(cell projection organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|interpro:IPR029611|interpro:IPR031470|refseq:NP_861537.2|refseq:XP_006510222.1|refseq:XP_006510223.1|dip:DIP-61755N	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:o2OdE14JA/OPojF9+WKrO4ymuO010090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q8VDC1	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-16727814|ensembl:ENSMUSP00000081764|ensembl:ENSMUSP00000133222|uniprotkb:Q3V385|uniprotkb:Q7TMT0|uniprotkb:Q8BJN2	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:fyco1_mouse(display_long)|uniprotkb:Fyco1(gene name)|psi-mi:Fyco1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000025241(gene)|ensembl:ENSMUST00000084715(transcript)|ensembl:ENSMUST00000167595(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:1901098"(positive regulation of autophagosome maturation)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR004012(RUN)|interpro:IPR009038(GOLD)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR036598|interpro:IPR037213|interpro:IPR042654|rcsb pdb:5WRD|refseq:NP_001103723.2|refseq:NP_683727.3|refseq:XP_017168648.1	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:UQrU+0SySU+oBd+pE2OneGw0oog10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:E9PX29	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-16726177|ensembl:ENSMUSP00000011895	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:e9px29_mouse(display_long)|uniprotkb:Sptbn4(gene name)|psi-mi:Sptbn4(display_short)|uniprotkb:Spnb4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000011751(gene)|ensembl:ENSMUST00000011895(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008091"(spectrin)|go:"GO:0009566"(fertilization)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022414"(reproductive process)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0030534"(adult behavior)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043203"(axon hillock)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0051693"(actin filament capping)|go:"GO:0061337"(cardiac conduction)|go:"GO:0070852"(cell body fiber)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|rcsb pdb:6M3Q|rcsb pdb:6M3R|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|go:"GO:0002028"(regulation of sodium ion transport)|refseq:NP_115999.2	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:3opwQ0kPX0QazJZ879BT5RmTr6A10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P05064	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-494220|ensembl:ENSMUSP00000032934|ensembl:ENSMUSP00000101955	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:aldoa_mouse(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Aldolase 1(gene name synonym)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short)|uniprotkb:Aldo1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:XP_006507273.1|refseq:XP_006507274.1|refseq:NP_001170779.1|refseq:NP_031464.1|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061827"(sperm head)|go:"GO:0005886"(plasma membrane)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|ensembl:ENSMUSG00000030695(gene)|ensembl:ENSMUST00000032934(transcript)|ensembl:ENSMUST00000106348(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0002020"(protease binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|mint:P05064|reactome:R-MMU-114608|reactome:R-MMU-6798695|reactome:R-MMU-70171|reactome:R-MMU-70263|interpro:IPR029768	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:m116/AX8vWkh1JCGOnEZv9ZOU9010090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q80WJ7	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-774530|uniprotkb:Q3U9F8|uniprotkb:Q3UAQ8|uniprotkb:Q8BN67|uniprotkb:Q8CBT9|uniprotkb:Q8CDL0|uniprotkb:B2RSG8|uniprotkb:Q05CM0|uniprotkb:Q8CGI7|uniprotkb:Q9D052|ensembl:ENSMUSP00000022865	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:lyric_mouse(display_long)|uniprotkb:Lysine-rich CEACAM1 co-isolated protein(gene name synonym)|uniprotkb:3D3/LYRIC(gene name synonym)|uniprotkb:Metastasis adhesion protein(gene name synonym)|uniprotkb:Mtdh(gene name)|psi-mi:Mtdh(display_short)|uniprotkb:Lyric(gene name synonym)|uniprotkb:Metadherin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_080278.3|ensembl:ENSMUSG00000022255(gene)|ensembl:ENSMUST00000022865(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR031402|mint:Q80WJ7	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:AwHgSmY3V6vCx2st1bunWPSPIM810090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9WV02	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-6393090|ensembl:ENSMUSP00000110374|ensembl:ENSMUSP00000110378|uniprotkb:Q8C2U6|uniprotkb:Q9R0Y0	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:rbmx_mouse(display_long)|uniprotkb:Rbmx(gene name)|psi-mi:Rbmx(display_short)|uniprotkb:Hnrnpg(gene name synonym)|uniprotkb:Hnrpg(gene name synonym)|uniprotkb:Rbmxp1(gene name synonym)|uniprotkb:Rbmxrt(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000031134(gene)|ensembl:ENSMUST00000114726(transcript)|ensembl:ENSMUST00000114730(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044530"(supraspliceosomal complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012604(RBM1CTR)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9WV02|reactome:R-MMU-72163|reactome:R-MMU-72203|reactome:R-MMU-9013418|reactome:R-MMU-9013422|reactome:R-MMU-9696264|reactome:R-MMU-9696270|reactome:R-MMU-9696273|refseq:NP_035382.1|refseq:NP_001160095.1	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:ifrLkzQpL8VIx6Dmsc8SBVQzDSU10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q6PHZ2	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-2308458|uniprotkb:Q3UF87|uniprotkb:Q3UQH9|uniprotkb:Q5DTK4|uniprotkb:Q8CAC5|uniprotkb:Q9CZE2|ensembl:ENSMUSP00000143504	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:kcc2d_mouse(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_001020609.1|refseq:NP_076302.1|refseq:NP_001020610.1|refseq:NP_001280592.1|refseq:NP_001280593.1|dip:DIP-47638N|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000199300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q6PHZ2|rcsb pdb:6BAB|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P84078	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-2308190|uniprotkb:P10947|uniprotkb:P32889|uniprotkb:Q3THZ2|uniprotkb:Q3U849|uniprotkb:Q3UDG1|uniprotkb:Q3UF76|ensembl:ENSMUSP00000079905|ensembl:ENSMUSP00000126120	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:arf1_mouse(display_long)|uniprotkb:Arf1(gene name)|psi-mi:Arf1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_001123880.1|refseq:NP_031502.1|ensembl:ENSMUSG00000048076(gene)|ensembl:ENSMUST00000061242(transcript)|ensembl:ENSMUST00000163300(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84078|rcsb pdb:1O3Y|rcsb pdb:2J59|reactome:R-MMU-1660499|reactome:R-MMU-1660514|reactome:R-MMU-199992|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811438	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:zray9asm6VonxpuJpv0dRBspPt810090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:E9PYF4	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-20567186|ensembl:ENSMUSP00000097910	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:e9pyf4_mouse(display_long)|uniprotkb:Lmo7(gene name)|psi-mi:Lmo7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000033060(gene)|ensembl:ENSMUST00000100337(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0023051"(regulation of signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0042805"(actinin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003096(SM22/calponin)|interpro:IPR029978|interpro:IPR031865|interpro:IPR036034|interpro:IPR036872|reactome:R-MMU-8951664|reactome:R-MMU-983168|refseq:NP_963287.2	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:oDqPX33K17+hwBrHjUuj0O0uQMg10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9D2N4	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-296019|uniprotkb:P97319|uniprotkb:Q61498|uniprotkb:Q61499|uniprotkb:Q9QZZ5|uniprotkb:Q9WUL9|uniprotkb:Q9WUM0	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:dtna_mouse(display_long)|uniprotkb:Dtna(gene name)|psi-mi:Dtna(display_short)|uniprotkb:Dtn(gene name synonym)|uniprotkb:Alpha-dystrobrevin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016014"(dystrobrevin complex)|refseq:NP_001272736.1|refseq:NP_001272739.1|refseq:NP_001272746.1|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|refseq:NP_034217.2|interpro:IPR017432(Distrobrevin)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR043145|refseq:XP_017173306.1|refseq:XP_017173308.1|refseq:XP_017173310.1|refseq:XP_017173311.1|refseq:XP_017173312.1|refseq:XP_017173313.1|refseq:XP_017173315.1	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:gqIbCFldISt+vbYeRHs3sswGPWU10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P01027	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-4281083|uniprotkb:Q80XP1|ensembl:ENSMUSP00000024988|uniprotkb:Q61370	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:co3_mouse(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:HSE-MSF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000024164(gene)|ensembl:ENSMUST00000024988(transcript)|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001970"(positive regulation of activation of membrane attack complex)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0008289"(lipid binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031715"(C5L2 anaphylatoxin chemotactic receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035711|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:P01027|rcsb pdb:6XZU|reactome:R-MMU-173736|reactome:R-MMU-174577|reactome:R-MMU-198933|reactome:R-MMU-375276|reactome:R-MMU-381426|reactome:R-MMU-418594|reactome:R-MMU-6798695|reactome:R-MMU-8957275|reactome:R-MMU-977606|refseq:NP_033908.2	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:VGFRYhKETrS9O7cyeJZyxBFgBL410090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:O08807	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-494652|uniprotkb:Q3U8E4|uniprotkb:B1AZS7|ensembl:ENSMUSP00000026328	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:prdx4_mouse(display_long)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)|uniprotkb:Prdx4(gene name)|psi-mi:Prdx4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_058044.1|refseq:NP_001300640.1|dip:DIP-34137N|ensembl:ENSMUSG00000025289(gene)|ensembl:ENSMUST00000026328(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:O08807|rcsb pdb:3VWU|rcsb pdb:3VWV|rcsb pdb:3W8J|rcsb pdb:3WGX|reactome:R-MMU-6798695	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:86EzEedrO6v5Z2dnSB2fSPaV2hc10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P24270	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-2924912|uniprotkb:Q3TXQ6|ensembl:ENSMUSP00000028610	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:cata_mouse(display_long)|uniprotkb:Cat(gene name)|psi-mi:Cat(display_short)|uniprotkb:Cas-1(gene name synonym)|uniprotkb:Cas1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	go:"GO:0055093"(response to hyperoxia)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P24270|reactome:R-MMU-3299685|reactome:R-MMU-6798695|reactome:R-MMU-9033241|go:"GO:0051781"(positive regulation of cell division)|ensembl:ENSMUSG00000027187(gene)|ensembl:ENSMUST00000028610(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001822"(kidney development)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|refseq:NP_033934.2	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:Ahsw8/VMIQAUw7mWuBSFRn9g/3M10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q61176	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-6877135|ensembl:ENSMUSP00000020161|uniprotkb:Q3TB74|uniprotkb:Q3UEL0|uniprotkb:Q4FK78|uniprotkb:Q80VI4	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:argi1_mouse(display_long)|uniprotkb:Arg1(gene name)|psi-mi:Arg1(display_short)|uniprotkb:Liver-type arginase(gene name synonym)|uniprotkb:Type I arginase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000019987(gene)|ensembl:ENSMUST00000020161(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006525"(arginine metabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|interpro:IPR020855|interpro:IPR023696|mint:Q61176|reactome:R-MMU-6798695|reactome:R-MMU-70635|refseq:NP_031508.1	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:phr6GaswifM+5zKNDMLEtMIEXmg10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9CS72	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-20567176	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:flip1_mouse(display_long)|uniprotkb:Filip1(gene name)|psi-mi:Filip1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099010"(modification of postsynaptic structure)|interpro:IPR019131|reactome:R-MMU-9013405	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:KDSQqZFsIHQ8zEjYjk2Otjl39j010090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P18242	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-738562|ensembl:ENSMUSP00000121203	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:catd_mouse(display_long)|uniprotkb:Ctsd(gene name)|psi-mi:Ctsd(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_034113.1|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070201"(regulation of establishment of protein localization)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|go:"GO:0004190"(aspartic-type endopeptidase activity)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P18242|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|reactome:R-MMU-1442490|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|reactome:R-MMU-2022377|reactome:R-MMU-2132295|reactome:R-MMU-6798695|go:"GO:0010008"(endosome membrane)|go:"GO:0016787"(hydrolase activity)|ensembl:ENSMUSG00000007891(gene)|ensembl:ENSMUST00000151120(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0004175"(endopeptidase activity)	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:PrpcvWCAFSmTF9ECBCB/zMV6d9M10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P23116	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-2552342|uniprotkb:E9QQ50|ensembl:ENSMUSP00000025955|uniprotkb:Q62162|uniprotkb:Q60697	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:eif3a_mouse(display_long)|uniprotkb:Eif3a(gene name)|psi-mi:Eif3a(display_short)|uniprotkb:Csma(gene name synonym)|uniprotkb:Eif3(gene name synonym)|uniprotkb:Eif3s10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym)|uniprotkb:p162(gene name synonym)|uniprotkb:Centrosomin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000024991(gene)|ensembl:ENSMUST00000025955(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:P23116|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|go:"GO:0014069"(postsynaptic density)|refseq:NP_034253.3	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:oL2Xlz5tghN0YkjvCd3nXOj15Hk10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9R0Y5	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-777466|uniprotkb:A2AK80|uniprotkb:Q542C5|uniprotkb:Q9R0Y4|ensembl:ENSMUSP00000108902|ensembl:ENSMUSP00000108903	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:kad1_mouse(display_long)|uniprotkb:ATP-AMP transphosphorylase 1(gene name synonym)|uniprotkb:Myokinase(gene name synonym)|uniprotkb:Ak1(gene name)|psi-mi:Ak1(display_short)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	refseq:NP_001185719.1|refseq:NP_001185720.1|refseq:NP_001185721.1|refseq:NP_067490.1|refseq:XP_006497687.1|ensembl:ENSMUSG00000026817(gene)|ensembl:ENSMUST00000113277(transcript)|ensembl:ENSMUST00000113278(transcript)|go:"GO:0001520"(outer dense fiber)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0030017"(sarcomere)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046103"(inosine biosynthetic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|interpro:IPR028582|interpro:IPR033690|mint:Q9R0Y5|reactome:R-MMU-499943	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:HTydMeIFNEaVZDs7sEN7aLieuVg10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P49722	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-991661|ensembl:ENSMUSP00000129767|uniprotkb:E9Q3A4|uniprotkb:Q6ZWV8	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:psa2_mouse(display_long)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:Psma2(gene name)|psi-mi:Psma2(display_short)|uniprotkb:Lmpc3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000015671(gene)|ensembl:ENSMUST00000170836(transcript)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|mint:P49722|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-2467813|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|refseq:NP_032970.2	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:nKRiQheHfS3+3anLub61WsVVtFE10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P14602	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-299023|ensembl:ENSMUSP00000005077	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:P49817	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-1161338|uniprotkb:Q8C1X7|uniprotkb:Q8CBP4|uniprotkb:Q9QYH3|uniprotkb:Q9QYH4|ensembl:ENSMUSP00000007799|ensembl:ENSMUSP00000111116	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:cav1_mouse(display_long)|uniprotkb:Cav1(gene name)|psi-mi:Cav1(display_short)|uniprotkb:Cav(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	ensembl:ENSMUSG00000007655(gene)|ensembl:ENSMUST00000007799(transcript)|ensembl:ENSMUST00000115456(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006897"(endocytosis)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009617"(response to bacterium)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010656"(negative regulation of muscle cell apoptotic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0033612"(receptor serine/threonine kinase binding)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0042060"(wound healing)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0052547"(regulation of peptidase activity)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070836"(caveola assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090398"(cellular senescence)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001258"(negative regulation of cation channel activity)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|interpro:IPR018361|mint:P49817|reactome:R-MMU-203615|reactome:R-MMU-203641|reactome:R-MMU-210991|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|reactome:R-MMU-4641262|reactome:R-MMU-5218920|reactome:R-MMU-8980692|reactome:R-MMU-9009391|reactome:R-MMU-9013026|reactome:R-MMU-9013106|reactome:R-MMU-9013148|reactome:R-MMU-9013149|reactome:R-MMU-9013404|reactome:R-MMU-9013405|reactome:R-MMU-9013406|reactome:R-MMU-9013407|reactome:R-MMU-9013408|reactome:R-MMU-9013423|reactome:R-MMU-9035034|reactome:R-MMU-9696270|reactome:R-MMU-9696273|reactome:R-MMU-9696264|refseq:NP_001229993.1|refseq:NP_031642.1|refseq:XP_006505037.1|refseq:XP_006505038.1|refseq:XP_006505039.1|dip:DIP-35140N	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:63vvAW/JPjuk8ZV3ZqoYdsy4umQ10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q61234	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-295952|uniprotkb:Q8VEF3|ensembl:ENSMUSP00000028991	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:snta1_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)|uniprotkb:Snt1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0051117"(ATPase binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|mint:Q61234|rcsb pdb:1QAV|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|rcsb pdb:1Z86|rcsb pdb:1Z87|rcsb pdb:2ADZ|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|rcsb pdb:2PDZ|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|rcsb pdb:4HOP|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000028991(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|dip:DIP-32898N	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:ENtty34uPh1ZGRmhT4TTIM/OVpI10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:P11531	uniprotkb:Q9D8N0	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	intact:EBI-773880|uniprotkb:Q920C5|uniprotkb:Q9CRT5|uniprotkb:Q9CSU3|uniprotkb:Q9D004|ensembl:ENSMUSP00000093955	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:ef1g_mouse(display_long)|uniprotkb:eEF-1B gamma(gene name synonym)|uniprotkb:Eef1g(gene name)|psi-mi:Eef1g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567174|imex:IM-26422-13	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	go:"GO:0003746"(translation elongation factor activity)|dip:DIP-32124N|refseq:NP_080283.3|ensembl:ENSMUSG00000071644(gene)|ensembl:ENSMUST00000052248(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:Q9D8N0|reactome:R-MMU-156842	-	-	-	figure legend:Table S11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rogid:TsONpdlsFR2YmfxQmAH4ByI5/Bg10090	rigid:hchtbjQg0+/9rSU+y86BR4xCpLs	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q99K48	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-607499|ensembl:ENSMUSP00000033673|uniprotkb:Q63887|uniprotkb:Q9CYQ4|uniprotkb:Q9DBP2	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:nono_mouse(display_long)|uniprotkb:Nono(gene name)|psi-mi:Nono(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	ensembl:ENSMUSG00000031311(gene)|ensembl:ENSMUST00000033673(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q99K48|rcsb pdb:2CPJ|rcsb pdb:2RS8|refseq:NP_075633.2|refseq:NP_001239447.1|dip:DIP-34308N	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:78ly3/4yzdfLjl9d/cV6Ob/SFG810090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q91WK2	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-7466721|intact:MINT-4098428|ensembl:ENSMUSP00000022925	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:eif3h_mouse(display_long)|uniprotkb:Eif3h(gene name)|psi-mi:Eif3h(display_short)|uniprotkb:Eif3s3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_542366.1|ensembl:ENSMUSG00000022312(gene)|ensembl:ENSMUST00000022925(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:Q91WK2|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	-	comment:mint|function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. Associates with the p170 subunit of EIF3	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:mKyE784VSiEMqBaCyG2Vt9FhynM10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P97379	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-8319813|intact:MINT-1858459|uniprotkb:Q9R1B8|uniprotkb:Q3UL55|ensembl:ENSMUSP00000128244|ensembl:ENSMUSP00000128353|ensembl:ENSMUSP00000144456	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:g3bp2_mouse(display_long)|uniprotkb:G3bp2(gene name)|psi-mi:G3bp2(display_short)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_035946.2|refseq:NP_001074263.1|refseq:NP_001074266.1|refseq:XP_006534990.1|refseq:XP_006534991.1|ensembl:ENSMUSG00000029405(gene)|ensembl:ENSMUST00000164378(transcript)|ensembl:ENSMUST00000169094(transcript)|ensembl:ENSMUST00000202258(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR034377|interpro:IPR035979|interpro:IPR039539|mint:P97379	-	-	function:Probable scaffold protein that may be involved in mRNA transport|comment:mint	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:1MhDKzi09if4Beb23/9+ZTB0xKM10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:O70468	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	-	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q3UMF0	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-8344634|uniprotkb:Q69ZU2|uniprotkb:Q6NXM0|intact:MINT-4113017|uniprotkb:Q3UX63|uniprotkb:Q8BWH3|uniprotkb:Q7TQM8|intact:MINT-1861492	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:cobl1_mouse(display_long)|uniprotkb:Cobll1(gene name)|psi-mi:Cobll1(display_short)|uniprotkb:Coblr1(gene name synonym)|uniprotkb:Kiaa0977(gene name synonym)|uniprotkb:Cobl-related protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	interpro:IPR019025|refseq:NP_081501.1|refseq:NP_795999.2|mint:Q3UMF0|refseq:XP_017174487.1|interpro:IPR039895|go:"GO:0003785"(actin monomer binding)	-	-	comment:mint	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:juLXHREGj7krcZpAa0z0/xQwVas10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:O55135	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-2000040|ensembl:ENSMUSP00000029142	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:if6_mouse(display_long)|uniprotkb:Eif6(gene name)|psi-mi:Eif6(display_short)|uniprotkb:Itgb4bp(gene name synonym)|uniprotkb:B4 integrin interactor(gene name synonym)|uniprotkb:CAB(gene name synonym)|uniprotkb:"p27(BBP)"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_034709.1|ensembl:ENSMUSG00000027613(gene)|ensembl:ENSMUST00000029142(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0032868"(response to insulin)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR002769(Translation initiation factor IF6)	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:VJmvvyZWezpZRVjVk9l76P0AYtY10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q9Z1Q9	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-6123642|uniprotkb:Q9QUN2|ensembl:ENSMUSP00000084572	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:syvc_mouse(display_long)|uniprotkb:Vars1(gene name)|psi-mi:Vars1(display_short)|uniprotkb:Bat6(gene name synonym)|uniprotkb:G7a(gene name synonym)|uniprotkb:Protein G7a(gene name synonym)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)|uniprotkb:Vars(gene name synonym)|uniprotkb:Vars2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_035820.3|refseq:XP_017172884.1|ensembl:ENSMUSG00000007029(gene)|ensembl:ENSMUST00000087315(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004832"(valine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006438"(valyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033705|interpro:IPR036282|interpro:IPR037118|mint:Q9Z1Q9	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:gAbY8qZ5vHpLxCj9zbBarjEd1hk10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q8K3W2	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-20565174|uniprotkb:Q8BUL2|ensembl:ENSMUSP00000073502	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:lrc10_mouse(display_long)|uniprotkb:Heart-restricted leucine-rich repeat protein(gene name synonym)|uniprotkb:Lrrc10(gene name)|psi-mi:Lrrc10(display_short)|uniprotkb:Hrlrrp(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_666354.1|ensembl:ENSMUSG00000060187(gene)|ensembl:ENSMUST00000073834(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0055013"(cardiac muscle cell development)|interpro:IPR001611(Leucine-rich repeat)|go:"GO:0005634"(nucleus)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:iVf+u0C/TmZEEVpfHx0e2merlXA10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q9JHU4	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-645061|uniprotkb:E9QM71|ensembl:ENSMUSP00000018851	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:dyhc1_mouse(display_long)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_084514.2|ensembl:ENSMUSG00000018707(gene)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0003341"(cilium movement)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|ensembl:ENSMUST00000018851(transcript)|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR042219|mint:Q9JHU4|rcsb pdb:3ERR|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3WUQ|rcsb pdb:5AYH|rcsb pdb:6RZA|rcsb pdb:6RZB|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:sbED0xqQpe32T7I8ijeS3Xqlx7010090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:E9PZQ0	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-642079|uniprotkb:Q60834|uniprotkb:Q61779|uniprotkb:Q61780|uniprotkb:Q62173|uniprotkb:Q62196|uniprotkb:Q62235|uniprotkb:Q78EJ6|uniprotkb:Q7TNG1|uniprotkb:Q80UQ5|uniprotkb:Q80X16|uniprotkb:Q99JF9|ensembl:ENSMUSP00000137123	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:ryr1_mouse(display_long)|uniprotkb:Ryr1(gene name)|psi-mi:Ryr1(display_short)|uniprotkb:Skeletal muscle calcium release channel(gene name synonym)|uniprotkb:Skeletal muscle ryanodine receptor(gene name synonym)|uniprotkb:Skeletal muscle-type ryanodine receptor(gene name synonym)|uniprotkb:Type 1 ryanodine receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_033135.2|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013333(Ryanodine receptor, N-terminal)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016093(MIR motif)|interpro:IPR033215|interpro:IPR035761|interpro:IPR035762|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|reactome:R-MMU-2672351|reactome:R-MMU-5578775|interpro:IPR005821(Ion transport)|ensembl:ENSMUSG00000030592(gene)|ensembl:ENSMUST00000179893(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002020"(protease binding)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006936"(muscle contraction)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0014802"(terminal cisterna)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030314"(junctional membrane complex)|go:"GO:0030315"(T-tubule)|go:"GO:0005516"(calmodulin binding)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0031674"(I band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0043588"(skin development)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071313"(cellular response to caffeine)|go:"GO:0071318"(cellular response to ATP)|go:"GO:1990425"(ryanodine receptor complex)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|dip:DIP-29705N	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:D15D2E764B445573	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:7pqK+A18JdTdARXDh+VTkS0z73c10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q91WP6	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-20567437|uniprotkb:Q62258	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:spa3n_mouse(display_long)|uniprotkb:Serpina3n(gene name)|psi-mi:Serpina3n(display_short)|uniprotkb:Spi2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	rcsb pdb:1YXA|interpro:IPR023795|interpro:IPR023796|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR036186|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0009617"(response to bacterium)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0034097"(response to cytokine)|go:"GO:0043434"(response to peptide hormone)|interpro:IPR042178|interpro:IPR042185	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:eTvnlAlqilvsCUjKeR1M23yxpgY10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q9QXS1	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-774583|uniprotkb:Q9QXR8|uniprotkb:Q9QXR9|uniprotkb:Q6S384|uniprotkb:Q6S389|uniprotkb:Q6S394|uniprotkb:Q9CS65|uniprotkb:Q9QUT2|uniprotkb:Q9QXQ8|uniprotkb:Q9QXQ9|uniprotkb:Q9QXR0|uniprotkb:Q9QXR1|uniprotkb:Q9QXR2|uniprotkb:Q9QXR3|uniprotkb:Q9QXR4|uniprotkb:Q9QXR5|uniprotkb:Q9QXR6|uniprotkb:Q9QXR7|uniprotkb:Q9QXS0|uniprotkb:Q9QXS2|uniprotkb:Q9QXS3|uniprotkb:E9QN87|ensembl:ENSMUSP00000073124	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:plec_mouse(display_long)|uniprotkb:Plectin-6(gene name synonym)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_001157012.1|refseq:NP_001157014.1|refseq:NP_001157021.1|refseq:NP_001157675.1|refseq:NP_035247.2|refseq:NP_958791.2|refseq:NP_958796.2|dip:DIP-32004N|ensembl:ENSMUSG00000022565(gene)|ensembl:ENSMUST00000073418(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0043588"(skin development)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071944"(cell periphery)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR018159|interpro:IPR030269|interpro:IPR035915|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q9QXS1|rcsb pdb:1SH5|rcsb pdb:1SH6|rcsb pdb:4Q57|reactome:R-MMU-264870|reactome:R-MMU-446107	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:9cGCRGhjImLIGd9shNPJRdSpdoY10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q8K0E8	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-1634324|uniprotkb:Q91ZP1|ensembl:ENSMUSP00000039472	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:fibb_mouse(display_long)|uniprotkb:Fgb(gene name)|psi-mi:Fgb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_862897.1|ensembl:ENSMUSG00000033831(gene)|ensembl:ENSMUST00000048246(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:Q8K0E8|reactome:R-MMU-114608|reactome:R-MMU-140875|reactome:R-MMU-216083|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-5674135|reactome:R-MMU-5686938	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:bEenetOknasilOE63oJ+BAi+PlI10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:E9PV24	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-6252659|ensembl:ENSMUSP00000133117|intact:EBI-8314642|intact:MINT-1863401|uniprotkb:Q99K47	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:fiba_mouse(display_long)|uniprotkb:Fga(gene name)|psi-mi:Fga(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_034326.1|ensembl:ENSMUSG00000028001(gene)|ensembl:ENSMUST00000166581(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007596"(blood coagulation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072377"(blood coagulation, common pathway)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|go:"GO:0042730"(fibrinolysis)|interpro:IPR021996|interpro:IPR036056|interpro:IPR037579|mint:E9PV24|reactome:R-MMU-114608|reactome:R-MMU-140875|reactome:R-MMU-216083|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-381426|reactome:R-MMU-5674135|reactome:R-MMU-5686938|reactome:R-MMU-8957275|interpro:IPR020837|refseq:NP_001104518.1	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:c9u+80j+sNgwjFuQ5vnHBVKgLCg10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q8VCM7	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-6252682|ensembl:ENSMUSP00000037018|uniprotkb:Q8WUR3|uniprotkb:Q91ZP0	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:fibg_mouse(display_long)|uniprotkb:Fgg(gene name)|psi-mi:Fgg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	ensembl:ENSMUSG00000033860(gene)|ensembl:ENSMUST00000048486(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009306"(protein secretion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037581|mint:Q8VCM7|reactome:R-MMU-114608|reactome:R-MMU-140875|reactome:R-MMU-216083|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-381426|reactome:R-MMU-5674135|reactome:R-MMU-5686938|reactome:R-MMU-8957275|refseq:NP_598623.1	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:AmOFe/GrPI4CGlyrFHBM1QHxYOk10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q9D051	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-773622|uniprotkb:Q3TL86|uniprotkb:Q505N8|uniprotkb:Q99LW9|ensembl:ENSMUSP00000022268	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:odpb_mouse(display_long)|uniprotkb:Pdhb(gene name)|psi-mi:Pdhb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_077183.1|ensembl:ENSMUSG00000021748(gene)|ensembl:ENSMUST00000022268(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:Q9D051|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:FPts4odLhVgLVf3gEYdc9N5Wuak10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P80314	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-772351|uniprotkb:Q9R1U0|ensembl:ENSMUSP00000036288	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:tcpb_mouse(display_long)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:Cctb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_031662.2|refseq:XP_006513224.1|dip:DIP-32343N|ensembl:ENSMUSG00000034024(gene)|ensembl:ENSMUST00000047672(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80314|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6798695|reactome:R-MMU-6814122|reactome:R-MMU-9013418|reactome:R-MMU-9013422	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:1CGHdF6g9ZqNbyRmQ5l3eUgD5Ow10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P63101	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-354751|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q3TSF1|uniprotkb:Q5EBQ1|ensembl:ENSMUSP00000022894|ensembl:ENSMUSP00000105990|ensembl:ENSMUSP00000105991	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:1433z_mouse(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:SEZ-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_001240734.1|refseq:NP_001240735.1|refseq:NP_035870.1|refseq:XP_011243654.1|ensembl:ENSMUSG00000022285(gene)|ensembl:ENSMUST00000110361(transcript)|ensembl:ENSMUST00000110362(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|ensembl:ENSMUST00000022894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63101|reactome:R-MMU-111447|reactome:R-MMU-3769402|reactome:R-MMU-392517|reactome:R-MMU-430116|reactome:R-MMU-450604|reactome:R-MMU-512988|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-9013700|reactome:R-MMU-9614399|dip:DIP-31894N	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P80318	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-772361|ensembl:ENSMUSP00000001452	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:tcpg_mouse(display_long)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:Matricin(gene name synonym)|uniprotkb:mTRiC-P5(gene name synonym)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:Cctg(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_033966.1|dip:DIP-32344N|ensembl:ENSMUSG00000001416(gene)|ensembl:ENSMUST00000001452(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P80318|rcsb pdb:1GML|rcsb pdb:1GN1|reactome:R-MMU-390471|reactome:R-MMU-5620922|reactome:R-MMU-6814122	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:+jrWcoDzrkHivHA/h3aApt0gBFU10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:E9PX29	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-16726177|ensembl:ENSMUSP00000011895	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:e9px29_mouse(display_long)|uniprotkb:Sptbn4(gene name)|psi-mi:Sptbn4(display_short)|uniprotkb:Spnb4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	ensembl:ENSMUSG00000011751(gene)|ensembl:ENSMUST00000011895(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008091"(spectrin)|go:"GO:0009566"(fertilization)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022414"(reproductive process)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0030534"(adult behavior)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043203"(axon hillock)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0051693"(actin filament capping)|go:"GO:0061337"(cardiac conduction)|go:"GO:0070852"(cell body fiber)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|rcsb pdb:6M3Q|rcsb pdb:6M3R|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|go:"GO:0002028"(regulation of sodium ion transport)|refseq:NP_115999.2	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:3opwQ0kPX0QazJZ879BT5RmTr6A10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q02105	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-20567414|uniprotkb:Q6DI63|ensembl:ENSMUSP00000036747	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:c1qc_mouse(display_long)|uniprotkb:C1qc(gene name)|psi-mi:C1qc(display_short)|uniprotkb:C1qg(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_031600.2|refseq:XP_017175416.1|ensembl:ENSMUSG00000036896(gene)|ensembl:ENSMUST00000046332(transcript)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|mint:Q02105|reactome:R-MMU-166663|reactome:R-MMU-173623|reactome:R-MMU-977606	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:bS60z9qFSICByYWP9YbySA/E2dM10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q8BMF4	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-769141|uniprotkb:Q8K2G8|uniprotkb:Q8R339|uniprotkb:Q91ZB1|ensembl:ENSMUSP00000034567	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:odp2_mouse(display_long)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:Dlat(gene name)|psi-mi:Dlat(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_663589.3|ensembl:ENSMUSG00000000168(gene)|ensembl:ENSMUST00000034567(transcript)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030431"(sleep)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:Q8BMF4|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:I0x+9L5a4O6Bch+NFbNzYiONj+810090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P46660	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-400482|uniprotkb:Q61958|uniprotkb:Q8VCW5|ensembl:ENSMUSP00000041347	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:ainx_mouse(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:66 kDa neurofilament protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_666212.3|ensembl:ENSMUSG00000034336(gene)|ensembl:ENSMUST00000037636(transcript)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027703|interpro:IPR039008|mint:P46660	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:amjP0AajB8s2oXmV96wzyfz6evE10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q6PHZ2	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-2308458|uniprotkb:Q3UF87|uniprotkb:Q3UQH9|uniprotkb:Q5DTK4|uniprotkb:Q8CAC5|uniprotkb:Q9CZE2|ensembl:ENSMUSP00000143504	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:kcc2d_mouse(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)|uniprotkb:Kiaa4163(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_001020609.1|refseq:NP_076302.1|refseq:NP_001020610.1|refseq:NP_001280592.1|refseq:NP_001280593.1|dip:DIP-47638N|ensembl:ENSMUSG00000053819(gene)|ensembl:ENSMUST00000199300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:Q6PHZ2|rcsb pdb:6BAB|reactome:R-MMU-3371571|reactome:R-MMU-399719|reactome:R-MMU-438066|reactome:R-MMU-5576892|reactome:R-MMU-5578775|reactome:R-MMU-5673000|reactome:R-MMU-5673001|reactome:R-MMU-877300|reactome:R-MMU-936837	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:z2mz73Kq9gwpKgo2Todn0IxQpSI10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P84078	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-2308190|uniprotkb:P10947|uniprotkb:P32889|uniprotkb:Q3THZ2|uniprotkb:Q3U849|uniprotkb:Q3UDG1|uniprotkb:Q3UF76|ensembl:ENSMUSP00000079905|ensembl:ENSMUSP00000126120	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:arf1_mouse(display_long)|uniprotkb:Arf1(gene name)|psi-mi:Arf1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_001123880.1|refseq:NP_031502.1|ensembl:ENSMUSG00000048076(gene)|ensembl:ENSMUST00000061242(transcript)|ensembl:ENSMUST00000163300(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84078|rcsb pdb:1O3Y|rcsb pdb:2J59|reactome:R-MMU-1660499|reactome:R-MMU-1660514|reactome:R-MMU-199992|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811438	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:zray9asm6VonxpuJpv0dRBspPt810090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P53395	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-773148|uniprotkb:Q3TMF5|ensembl:ENSMUSP00000000349	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:odb2_mouse(display_long)|uniprotkb:"Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase"(gene name synonym)|uniprotkb:Dihydrolipoamide branched chain transacylase(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex(gene name synonym)|uniprotkb:Dbt(gene name)|psi-mi:Dbt(display_short)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_034152.2|ensembl:ENSMUSG00000000340(gene)|ensembl:ENSMUST00000000349(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0031405"(lipoic acid binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043754"("dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity")|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P53395|reactome:R-MMU-389661|reactome:R-MMU-70895|reactome:R-MMU-9013407	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:/g3DD7tq0CE5mqTJD4ZifLuIy5E10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q7TMM9	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-2255578|ensembl:ENSMUSP00000060246	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:tbb2a_mouse(display_long)|uniprotkb:Tubb2(gene name synonym)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_033476.1|ensembl:ENSMUSG00000058672(gene)|ensembl:ENSMUST00000056427(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q7TMM9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:E9PV66	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-20567384|ensembl:ENSMUSP00000083810	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:e9pv66_mouse(display_long)|uniprotkb:Myo18b(gene name)|psi-mi:Myo18b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_083177.2|refseq:XP_006535325.1|ensembl:ENSMUSG00000072720(gene)|ensembl:ENSMUST00000086617(transcript)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030018"(Z disc)|go:"GO:0031941"(filamentous actin)|go:"GO:0055013"(cardiac muscle cell development)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR027417|interpro:IPR028561|interpro:IPR036064|interpro:IPR036961	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:RQQqXe76kuMOps8pmPQwkyCpp2410090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P84244	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-120681|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q3TW79|uniprotkb:Q3U6D6|uniprotkb:Q569U8|uniprotkb:Q5HZY8|uniprotkb:Q6TXQ5|uniprotkb:Q8VDJ2|uniprotkb:Q9D0H3|uniprotkb:Q9V3W4|ensembl:ENSMUSP00000016703|ensembl:ENSMUSP00000102062|ensembl:ENSMUSP00000124509|ensembl:ENSMUSP00000125104	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:h33_mouse(display_long)|uniprotkb:H3-3a(gene name)|psi-mi:H3-3a(display_short)|uniprotkb:H3-3b(gene name)|psi-mi:H3-3b(display_short)|uniprotkb:H3.3a(gene name synonym)|uniprotkb:H3.3b(gene name synonym)|uniprotkb:H3f3a(gene name synonym)|uniprotkb:H3f3b(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_032236.1|refseq:NP_032237.1|ensembl:ENSMUSG00000016559(gene)|ensembl:ENSMUSG00000060743(gene)|ensembl:ENSMUST00000016703(transcript)|ensembl:ENSMUST00000106454(transcript)|ensembl:ENSMUST00000161308(transcript)|ensembl:ENSMUST00000162814(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001740"(Barr body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006997"(nucleus organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0007566"(embryo implantation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008584"(male gonad development)|go:"GO:0007286"(spermatid development)|go:"GO:0009725"(response to hormone)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048477"(oogenesis)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:1902340"(negative regulation of chromosome condensation)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84244|rcsb pdb:2RVN|rcsb pdb:5XM0|rcsb pdb:5XM1|reactome:R-MMU-212300|reactome:R-MMU-2559580|reactome:R-MMU-2559582|reactome:R-MMU-427359|reactome:R-MMU-427413|reactome:R-MMU-5250924|reactome:R-MMU-5578749|reactome:R-MMU-5625886|reactome:R-MMU-73728|reactome:R-MMU-73772|reactome:R-MMU-9018519|reactome:R-MMU-983231|reactome:R-MMU-8936459|refseq:XP_006532311.1|dip:DIP-35190N	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:cRqA5/IBNfIbbxAnbwLqzXip20I10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P35486	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-773613|ensembl:ENSMUSP00000033662	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:odpa_mouse(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:Pdha1(gene name)|psi-mi:Pdha1(display_short)|uniprotkb:Pdha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_032836.1|ensembl:ENSMUSG00000031299(gene)|ensembl:ENSMUST00000033662(transcript)|go:"GO:0004738"(pyruvate dehydrogenase activity)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0043209"(myelin sheath)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|interpro:IPR029061|mint:P35486|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:QIfCMikb5tVYwefUZs3+5ut/nbY10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q08189	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-11707008|uniprotkb:A1L343|uniprotkb:A2ANC3|ensembl:ENSMUSP00000105928	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:tgm3_mouse(display_long)|uniprotkb:Tgm3(gene name)|psi-mi:Tgm3(display_short)|uniprotkb:Tgase3(gene name synonym)|uniprotkb:Transglutaminase E(gene name synonym)|uniprotkb:Transglutaminase-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_033400.2|ensembl:ENSMUSG00000027401(gene)|ensembl:ENSMUST00000110299(transcript)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0001533"(cornified envelope)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031424"(keratinization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0043163"(cell envelope organization)|go:"GO:0043588"(skin development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:Rlc2Bws2SyOa3yZUvaDb7eVm9W010090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P05201	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-494448|intact:EBI-2308970|uniprotkb:Q3UJH8|ensembl:ENSMUSP00000026196	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:aatc_mouse(display_long)|uniprotkb:Transaminase A(gene name synonym)|uniprotkb:Glutamate oxaloacetate transaminase 1(gene name synonym)|uniprotkb:Cysteine aminotransferase, cytoplasmic(gene name synonym)|uniprotkb:Cysteine transaminase, cytoplasmic(gene name synonym)|uniprotkb:Got1(gene name)|psi-mi:Got1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_034454.2|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0004609"(phosphatidylserine decarboxylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006114"(glycerol biosynthetic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0019550"(glutamate catabolic process to aspartate)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|go:"GO:0030170"(pyridoxal phosphate binding)|ensembl:ENSMUSG00000025190(gene)|ensembl:ENSMUST00000026196(transcript)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032966"(negative regulation of collagen biosynthetic process)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0043679"(axon terminus)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0047801"(L-cysteine transaminase activity)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060290"(transdifferentiation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:1990267"(response to transition metal nanoparticle)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P05201|reactome:R-MMU-70263|reactome:R-MMU-8963693	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:4if14ijxqySSUHcJ2S2EXDyBzZQ10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q60664	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-688116|uniprotkb:Q7TMU8	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:irag2_mouse(display_long)|uniprotkb:Irag2(gene name)|psi-mi:Irag2(display_short)|uniprotkb:Jaw1(gene name synonym)|uniprotkb:Lrmp(gene name synonym)|uniprotkb:Lymphoid-restricted membrane protein(gene name synonym)|uniprotkb:Protein Jaw1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	interpro:IPR008677(MRVI1)|refseq:NP_001268909.1|go:"GO:0000922"(spindle pole)|go:"GO:0002376"(immune system process)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005694"(chromosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006997"(nucleus organization)|go:"GO:0007338"(single fertilization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:DyUxo5y3yVY7O83jUohbdC42XsA10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P18242	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-738562|ensembl:ENSMUSP00000121203	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:catd_mouse(display_long)|uniprotkb:Ctsd(gene name)|psi-mi:Ctsd(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_034113.1|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070201"(regulation of establishment of protein localization)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|go:"GO:0004190"(aspartic-type endopeptidase activity)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P18242|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|reactome:R-MMU-1442490|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|reactome:R-MMU-2022377|reactome:R-MMU-2132295|reactome:R-MMU-6798695|go:"GO:0010008"(endosome membrane)|go:"GO:0016787"(hydrolase activity)|ensembl:ENSMUSG00000007891(gene)|ensembl:ENSMUST00000151120(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0004175"(endopeptidase activity)	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:PrpcvWCAFSmTF9ECBCB/zMV6d9M10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q8VIJ6	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-6094576|uniprotkb:A2A7U6|uniprotkb:Q9ERW2|ensembl:ENSMUSP00000030623	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:sfpq_mouse(display_long)|uniprotkb:Sfpq(gene name)|psi-mi:Sfpq(display_short)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:Psf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_076092.1|ensembl:ENSMUSG00000028820(gene)|ensembl:ENSMUST00000030623(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051276"(chromosome organization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:Q8VIJ6|reactome:R-MMU-8849468	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:9mciNgfKrEvyAv7kjs55FHlUtRY10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q9ESB3	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-20567331|uniprotkb:Q6YK32|uniprotkb:Q6YKA2|uniprotkb:Q99PS5|uniprotkb:Q99PS6	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:hrg_mouse(display_long)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym)|uniprotkb:Hrg(gene name)|psi-mi:Hrg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	reactome:R-MMU-114608|reactome:R-MMU-75205|refseq:NP_444406.2|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|go:"GO:0001525"(angiogenesis)|go:"GO:0002839"(positive regulation of immune response to tumor cell)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006935"(chemotaxis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015886"(heme transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0020037"(heme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031982"(vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0034395"(regulation of transcription from RNA polymerase II promoter in response to iron)|go:"GO:0036019"(endolysosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097037"(heme export)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000504"(positive regulation of blood vessel remodeling)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:1d8/1GRDzMUgvhpOya054oh13tU10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:O08677	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-738531|uniprotkb:O08676|uniprotkb:Q91XK5|uniprotkb:Q32MX7|uniprotkb:Q6S9I1	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:kng1_mouse(display_long)|uniprotkb:Kng1(gene name)|psi-mi:Kng1(display_short)|uniprotkb:Kng(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	interpro:IPR027358|refseq:NP_001095881.1|refseq:NP_075614.1|interpro:IPR002395(HMW kininogen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0042311"(vasodilation)|go:"GO:0062023"(collagen-containing extracellular matrix)|mint:O08677	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:b3fkbWY+mVAwNAWfKdrAYPU2dtM10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q8BKZ9	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-6877565|ensembl:ENSMUSP00000011058	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:odpx_mouse(display_long)|uniprotkb:Pdhx(gene name)|psi-mi:Pdhx(display_short)|uniprotkb:Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Lipoyl-containing pyruvate dehydrogenase complex component X(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	ensembl:ENSMUSG00000010914(gene)|ensembl:ENSMUST00000011058(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:Q8BKZ9|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268|refseq:NP_780303.1	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:5b1n89M4YLpENMk4kqCsO2oQqJ010090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q5SX40	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-1634619|uniprotkb:Q32P18|ensembl:ENSMUSP00000018637|ensembl:ENSMUSP00000075147|ensembl:ENSMUSP00000117569	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:myh1_mouse(display_long)|uniprotkb:Myh1(gene name)|psi-mi:Myh1(display_short)|uniprotkb:Myosin heavy chain 1(gene name synonym)|uniprotkb:Myosin heavy chain 2x(gene name synonym)|uniprotkb:Myosin heavy chain, skeletal muscle, adult 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_109604.1|refseq:XP_017169807.1|ensembl:ENSMUSG00000056328(gene)|ensembl:ENSMUST00000018637(transcript)|ensembl:ENSMUST00000075734(transcript)|ensembl:ENSMUST00000124516(transcript)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005859"(muscle myosin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0014704"(intercalated disc)|go:"GO:0031672"(A band)|go:"GO:0032982"(myosin filament)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0051015"(actin filament binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q5SX40	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:LR8EokV3LoiQJ3ykzeelwyDCO6Q10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P84099	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-2526813|uniprotkb:P14118|uniprotkb:P22908|ensembl:ENSMUSP00000017548	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:rl19_mouse(display_long)|uniprotkb:Rpl19(gene name)|psi-mi:Rpl19(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_033104.2|ensembl:ENSMUSG00000017404(gene)|ensembl:ENSMUST00000017548(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0097421"(liver regeneration)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970|interpro:IPR039547|mint:P84099|rcsb pdb:1K8D|rcsb pdb:6SWA|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72689|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:sYEwdB8ySbxh3iL0uqlfRRVFiWw10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P49722	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-991661|ensembl:ENSMUSP00000129767|uniprotkb:E9Q3A4|uniprotkb:Q6ZWV8	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:psa2_mouse(display_long)|uniprotkb:Proteasome component C3(gene name synonym)|uniprotkb:Macropain subunit C3(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C3(gene name synonym)|uniprotkb:Psma2(gene name)|psi-mi:Psma2(display_short)|uniprotkb:Lmpc3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	ensembl:ENSMUSG00000015671(gene)|ensembl:ENSMUST00000170836(transcript)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0009615"(response to virus)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034644|mint:P49722|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-2467813|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-6798695|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|refseq:NP_032970.2	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:nKRiQheHfS3+3anLub61WsVVtFE10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q76MZ3	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-400413|ensembl:ENSMUSP00000007708	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:2aaa_mouse(display_long)|uniprotkb:Ppp2r1a(gene name)|psi-mi:Ppp2r1a(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_058587.1|go:"GO:0051306"(mitotic sister chromatid separation)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1990405"(protein antigen binding)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:Q76MZ3|rcsb pdb:2IAE|rcsb pdb:2PF4|rcsb pdb:3FGA|rcsb pdb:6EF4|reactome:R-MMU-113501|reactome:R-MMU-1295596|reactome:R-MMU-141444|reactome:R-MMU-180024|reactome:R-MMU-195253|reactome:R-MMU-196299|reactome:R-MMU-198753|reactome:R-MMU-202670|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-2995383|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-389513|reactome:R-MMU-432142|reactome:R-MMU-4641262|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-5673000|reactome:R-MMU-5675221|reactome:R-MMU-6804757|reactome:R-MMU-6811558|reactome:R-MMU-68877|reactome:R-MMU-69231|reactome:R-MMU-69273|reactome:R-MMU-8854518|reactome:R-MMU-9648025|reactome:R-MMU-975957|ensembl:ENSMUSG00000007564(gene)|ensembl:ENSMUST00000007708(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051232"(meiotic spindle elongation)|dip:DIP-29429N	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:0tnO11U1SNOOT46j23f7dim8O8k10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P57776	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-4284702|uniprotkb:Q68FG5|uniprotkb:Q9CWW2|uniprotkb:Q9CWY1|uniprotkb:Q9CYD4|uniprotkb:Q9CYJ5	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:ef1d_mouse(display_long)|uniprotkb:Eef1d(gene name)|psi-mi:Eef1d(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_075729.2|refseq:NP_083939.1|interpro:IPR018940|interpro:IPR014717(Translation elongation  factor EF1B/ribosomal protein S6)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|refseq:NP_001272358.1|refseq:NP_001272359.1|refseq:NP_001272360.1|refseq:NP_001272361.1|refseq:NP_001272362.1|refseq:NP_001272363.1|mint:P57776|interpro:IPR036219|go:"GO:0009299"(mRNA transcription)|go:"GO:0010941"(regulation of cell death)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0045202"(synapse)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|reactome:R-MMU-156842|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:u9Szyf5Sgd3WAlW/np+9e0VpsfA10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q61234	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-295952|uniprotkb:Q8VEF3|ensembl:ENSMUSP00000028991	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:snta1_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)|uniprotkb:Snt1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0051117"(ATPase binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|mint:Q61234|rcsb pdb:1QAV|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|rcsb pdb:1Z86|rcsb pdb:1Z87|rcsb pdb:2ADZ|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|rcsb pdb:2PDZ|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|rcsb pdb:4HOP|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000028991(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|dip:DIP-32898N	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:ENtty34uPh1ZGRmhT4TTIM/OVpI10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:O70435	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-991671|ensembl:ENSMUSP00000125548	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:psa3_mouse(display_long)|uniprotkb:Macropain subunit C8(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C8(gene name synonym)|uniprotkb:Proteasome subunit K(gene name synonym)|uniprotkb:Proteasome component C8(gene name synonym)|uniprotkb:Psma3(gene name)|psi-mi:Psma3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_035314.3|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|interpro:IPR001353(20S proteasome, A and B subunits)|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|interpro:IPR023332|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|interpro:IPR029055|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|interpro:IPR037555|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|ensembl:ENSMUSG00000060073(gene)|ensembl:ENSMUST00000160027(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045202"(synapse)|go:"GO:0052548"(regulation of endopeptidase activity)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|refseq:XP_017170485.1	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:NgV6tyZ0v25UGZ5FkGZNNLMJVjQ10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:O08749	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-773199|uniprotkb:Q3TG55|uniprotkb:Q3U5W5|uniprotkb:Q3UWP7|uniprotkb:Q99LD3|ensembl:ENSMUSP00000106481	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:dldh_mouse(display_long)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Dld(gene name)|psi-mi:Dld(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_031887.2|ensembl:ENSMUSG00000020664(gene)|ensembl:ENSMUST00000110857(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005929"(cilium)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043209"(myelin sheath)|go:"GO:0043544"(lipoamide binding)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:O08749|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-6783984|reactome:R-MMU-70268|reactome:R-MMU-70895|reactome:R-MMU-71064|reactome:R-MMU-71403	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:6j/8rw4lkNMW4Lo5sGoRdDJBk2w10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q62407	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-20565270|uniprotkb:Q3TPH8|uniprotkb:Q6P5V1|uniprotkb:Q80TF7|uniprotkb:Q80ZN0|uniprotkb:Q8BZF4|uniprotkb:Q9EQJ5	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:speg_mouse(display_long)|uniprotkb:Aortic preferentially expressed protein 1(gene name synonym)|uniprotkb:Speg(gene name)|psi-mi:Speg(display_short)|uniprotkb:Apeg1(gene name synonym)|uniprotkb:Kiaa1297(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_001078839.1|refseq:NP_001078840.1|refseq:NP_001166948.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR036116|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR015726(Serine/threonine protein kinase, striated muscle)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060541"(respiratory system development)|go:"GO:0072359"(circulatory system development)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:T1Eyb7kspnNUOYfrHfYJmdMQ0GQ10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P26231	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-647895|ensembl:ENSMUSP00000049007	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:ctna1_mouse(display_long)|uniprotkb:102 kDa cadherin-associated protein(gene name synonym)|uniprotkb:CAP102(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Ctnna1(gene name)|psi-mi:Ctnna1(display_short)|uniprotkb:Catna1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_033948.1|refseq:XP_011245120.1|dip:DIP-35299N|ensembl:ENSMUSG00000037815(gene)|ensembl:ENSMUST00000042345(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P26231|rcsb pdb:1DOV|rcsb pdb:1DOW|rcsb pdb:1L7C|rcsb pdb:4E17|rcsb pdb:4E18|rcsb pdb:4K1N|rcsb pdb:5Y04|rcsb pdb:6DV1|rcsb pdb:6O3E|rcsb pdb:6WVT|reactome:R-MMU-418990|reactome:R-MMU-5218920|reactome:R-MMU-525793|reactome:R-MMU-5626467	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:2GScCoVKWPHfjBJE6Gm6yVmO/IA10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q80VP2	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-20567308|uniprotkb:Q8BK23|ensembl:ENSMUSP00000045827	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:spat7_mouse(display_long)|uniprotkb:Spata7(gene name)|psi-mi:Spata7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_849245.2|refseq:XP_011242281.1|ensembl:ENSMUSG00000021007(gene)|ensembl:ENSMUST00000048402(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|go:"GO:1903621"(protein localization to photoreceptor connecting cilium)|interpro:IPR029357	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:pi0BcVpwFuv5yjL0fmGfW1jtavc10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q9R1P0	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-772804|uniprotkb:Q3THT1|ensembl:ENSMUSP00000034848	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:psa4_mouse(display_long)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:Psma4(gene name)|psi-mi:Psma4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_036096.1|refseq:XP_006511261.1|ensembl:ENSMUSG00000032301(gene)|ensembl:ENSMUST00000034848(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:Q9R1P0|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:6Dp8VODK8RbwARcOjjpMbvCN1pU10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q4ACU6	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-771450|uniprotkb:Q69ZD8|intact:EBI-8401154|intact:MINT-4130064|uniprotkb:F8S0X0|uniprotkb:F8S0X2|uniprotkb:F8S0X3|uniprotkb:F8S0X5|uniprotkb:F8S0X6|uniprotkb:Q9JJZ3|uniprotkb:S6BMD3|uniprotkb:S6CCV8|ensembl:ENSMUSP00000104932	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:shan3_mouse(display_long)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Kiaa1650(gene name synonym)|uniprotkb:Prosap2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_067398.2|dip:DIP-32262N|ensembl:ENSMUSG00000022623(gene)|ensembl:ENSMUST00000109309(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q4ACU6|rcsb pdb:3O5N|rcsb pdb:5IZU|rcsb pdb:6KYH|rcsb pdb:6KYK|reactome:R-MMU-6794361|reactome:R-MMU-8853659	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:40CZZZ4qetQSv6a6gsUMVeL0c+o10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:Q9D8N0	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-773880|uniprotkb:Q920C5|uniprotkb:Q9CRT5|uniprotkb:Q9CSU3|uniprotkb:Q9D004|ensembl:ENSMUSP00000093955	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:ef1g_mouse(display_long)|uniprotkb:eEF-1B gamma(gene name synonym)|uniprotkb:Eef1g(gene name)|psi-mi:Eef1g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	go:"GO:0003746"(translation elongation factor activity)|dip:DIP-32124N|refseq:NP_080283.3|ensembl:ENSMUSG00000071644(gene)|ensembl:ENSMUST00000052248(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:Q9D8N0|reactome:R-MMU-156842	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:TsONpdlsFR2YmfxQmAH4ByI5/Bg10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:E9Q401	uniprotkb:P11404	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	intact:EBI-3504145|uniprotkb:Q91W23|ensembl:ENSMUSP00000070709	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:fabph_mouse(display_long)|uniprotkb:Fabp3(gene name)|psi-mi:Fabp3(display_short)|uniprotkb:Fabph1(gene name synonym)|uniprotkb:Fatty acid-binding protein 3(gene name synonym)|uniprotkb:Heart-type fatty acid-binding protein(gene name synonym)|uniprotkb:Mammary-derived growth inhibitor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567306|imex:IM-26422-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	refseq:NP_034304.1|ensembl:ENSMUSG00000028773(gene)|ensembl:ENSMUST00000070532(transcript)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0032365"(intracellular lipid transport)|go:"GO:0032868"(response to insulin)|go:"GO:0036041"(long-chain fatty acid binding)|go:"GO:0042493"|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0050543"(icosatetraenoic acid binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0070538"(oleic acid binding)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0140214"(positive regulation of long-chain fatty acid import into cell)|go:"GO:2001245"(regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:P11404|reactome:R-MMU-163560	-	-	-	figure legend:Table S12|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/06/04	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rogid:dQml5A1cAEZVjH9htxeLPe4NrvI10090	rigid:Jn6tj6xM6HR+iozhxKvgqfatnpI	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q60994	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-7264589|uniprotkb:Q9DC68|uniprotkb:Q62400|uniprotkb:Q6GTX4|intact:MINT-4563800|ensembl:ENSMUSP00000023593	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:adipo_mouse(display_long)|uniprotkb:Apm1(gene name synonym)|uniprotkb:Adipocyte, C1q and collagen domain-containing protein(gene name synonym)|uniprotkb:30 kDa adipocyte complement-related protein(gene name synonym)|uniprotkb:Adipocyte complement-related 30 kDa protein(gene name synonym)|uniprotkb:Adipocyte-specific protein AdipoQ(gene name synonym)|uniprotkb:Adipoq(gene name)|psi-mi:Adipoq(display_short)|uniprotkb:Acdc(gene name synonym)|uniprotkb:Acrp30(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_033735.3|ensembl:ENSMUST00000023593(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007584"(response to nutrient)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009617"(response to bacterium)|go:"GO:0009744"(response to sucrose)|go:"GO:0009749"(response to glucose)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0009986"(cell surface)|go:"GO:0010467"(gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014823"(response to activity)|go:"GO:0019395"(fatty acid oxidation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033034"(positive regulation of myeloid cell apoptotic process)|go:"GO:0033691"(sialic acid binding)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035690"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045471"(response to ethanol)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045923"(positive regulation of fatty acid metabolic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046888"(negative regulation of hormone secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|ensembl:ENSMUSG00000022878(gene)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070543"(response to linoleic acid)|go:"GO:0070994"(detection of oxidative stress)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090317"(negative regulation of intracellular protein transport)|go:"GO:0110113"(positive regulation of lipid transporter activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1905598"(negative regulation of low-density lipoprotein receptor activity)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000467"("positive regulation of glycogen (starch) synthase activity")|go:"GO:2000478"(positive regulation of metanephric glomerular visceral epithelial cell development)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000534"(positive regulation of renal albumin absorption)|go:"GO:2000584"(negative regulation of platelet-derived growth factor receptor-alpha signaling pathway)|go:"GO:2000590"(negative regulation of metanephric mesenchymal cell migration)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR028572|mint:Q60994|rcsb pdb:1C28|rcsb pdb:1C3H|reactome:R-MMU-163680|dip:DIP-44111N	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	comment:mint|function:Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:gWG6bUFwmZsDW8jVpPjubtFADgI10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:P50096	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-8393359|intact:MINT-4098666|uniprotkb:Q7TSG7|ensembl:ENSMUSP00000077289|ensembl:ENSMUSP00000124541|ensembl:ENSMUSP00000124931	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:imdh1_mouse(display_long)|uniprotkb:Impdh1(gene name)|psi-mi:Impdh1(display_short)|uniprotkb:IMPDH-I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_001289862.1|refseq:NP_001289863.1|refseq:NP_035959.2|ensembl:ENSMUSG00000003500(gene)|ensembl:ENSMUST00000078155(transcript)|ensembl:ENSMUST00000159124(transcript)|ensembl:ENSMUST00000162099(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P50096|reactome:R-MMU-6798695|reactome:R-MMU-73817	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	function:Rate limiting enzyme in the de novo synthesis of guanine nucleotides and therefore is involved in the regulation of cell growth. It may also have a role in the development of malignancy and the growth progression of some tumors|comment:mint	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:eVfUWplQAsNveP8QU4IgTlgK3Co10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:O55135	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-2000040|ensembl:ENSMUSP00000029142	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:if6_mouse(display_long)|uniprotkb:Eif6(gene name)|psi-mi:Eif6(display_short)|uniprotkb:Itgb4bp(gene name synonym)|uniprotkb:B4 integrin interactor(gene name synonym)|uniprotkb:CAB(gene name synonym)|uniprotkb:"p27(BBP)"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_034709.1|ensembl:ENSMUSG00000027613(gene)|ensembl:ENSMUST00000029142(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0032868"(response to insulin)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR002769(Translation initiation factor IF6)	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:VJmvvyZWezpZRVjVk9l76P0AYtY10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:P11531	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-295928|uniprotkb:O35653|uniprotkb:Q60703|ensembl:ENSMUSP00000109633|uniprotkb:A2A9Z0	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:dmd_mouse(display_long)|uniprotkb:Dmd(gene name)|psi-mi:Dmd(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0007568"(aging)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|ensembl:ENSMUSG00000045103(gene)|ensembl:ENSMUST00000114000(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005840"(ribosome)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007517"(muscle organ development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0021629"(olfactory nerve structural organization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0014904"(myotube cell development)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060857"(establishment of glial blood-brain barrier)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:0097449"(astrocyte projection)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P11531|reactome:R-MMU-390522|refseq:NP_031894.1|dip:DIP-32899N	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:J4D47RN0ex7Ptw24IPpFWOP4RSY10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:P00405	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-773506|uniprotkb:Q85K21|ensembl:ENSMUSP00000080994	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:cox2_mouse(display_long)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)|uniprotkb:Mtco2(gene name)|psi-mi:Mtco2(display_short)|uniprotkb:COII(gene name synonym)|uniprotkb:mt-Co2(gene name synonym)|uniprotkb:COX2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_904331.1|ensembl:ENSMUSG00000064354(gene)|ensembl:ENSMUST00000082405(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00405|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:oM1rnc+HJvDAF3+Z9fgK35b0UIw10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:E9Q401	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-643628|ensembl:ENSMUSP00000021750|uniprotkb:O70181|uniprotkb:Q62174|uniprotkb:Q62197|uniprotkb:Q9ERN6	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:ryr2_mouse(display_long)|uniprotkb:Ryr2(gene name)|psi-mi:Ryr2(display_short)|uniprotkb:Cardiac muscle ryanodine receptor(gene name synonym)|uniprotkb:Cardiac muscle ryanodine receptor-calcium release channel(gene name synonym)|uniprotkb:Type 2 ryanodine receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_076357.2|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072599"(establishment of protein localization to endoplasmic reticulum)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086029"(Purkinje myocyte to ventricular cardiac muscle cell signaling)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0071421"(manganese ion transmembrane transport)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:0098904"(regulation of AV node cell action potential)|go:"GO:0098907"(regulation of SA node cell action potential)|go:"GO:0098910"(regulation of atrial cardiac muscle cell action potential)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003032(Ryanodine receptor Ryr)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR005821(Ion transport)|interpro:IPR009460(Ryanodine Receptor TM 4-6)|interpro:IPR011992(EF-Hand type)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014808"(release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031000"(response to caffeine)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031672"(A band)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043621"(protein self-association)|go:"GO:0043924"(suramin binding)|go:"GO:0048763"(calcium-induced calcium release activity)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051284"(positive regulation of sequestering of calcium ion)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051775"(response to redox state)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060401"(cytosolic calcium ion transport)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071313"(cellular response to caffeine)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:4ETV|rcsb pdb:4KEI|rcsb pdb:4KEJ|rcsb pdb:4KEK|rcsb pdb:4L4H|interpro:IPR013333(Ryanodine receptor, N-terminal)|rcsb pdb:4L4I|rcsb pdb:4P9I|interpro:IPR013662(RyR and IP3R Homology associated)|rcsb pdb:4P9L|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|rcsb pdb:5C33|rcsb pdb:5VSN|rcsb pdb:6J6L|rcsb pdb:6MM5|rcsb pdb:6MM6|rcsb pdb:6MM7|interpro:IPR016093(MIR motif)|rcsb pdb:6MM8|interpro:IPR035761|rcsb pdb:6WOU|rcsb pdb:6WOV|reactome:R-MMU-2672351|interpro:IPR035762|reactome:R-MMU-5578775|interpro:IPR035764|interpro:IPR035910|interpro:IPR036300|interpro:IPR043136|mint:E9Q401|rcsb pdb:2MC2|rcsb pdb:3IM5|rcsb pdb:3IM6|rcsb pdb:3IM7|rcsb pdb:3QR5|ensembl:ENSMUSG00000021313(gene)|ensembl:ENSMUST00000021750(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003220"(left ventricular cardiac muscle tissue morphogenesis)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0005219"(ryanodine-sensitive calcium-release channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:HHxj8k5HJe0bbt0o041H0inQo0w10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q9JHU4	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-645061|uniprotkb:E9QM71|ensembl:ENSMUSP00000018851	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:dyhc1_mouse(display_long)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_084514.2|ensembl:ENSMUSG00000018707(gene)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0003341"(cilium movement)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024317|interpro:IPR024743|interpro:IPR027417|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|ensembl:ENSMUST00000018851(transcript)|interpro:IPR042222|interpro:IPR042228|interpro:IPR043157|interpro:IPR043160|interpro:IPR042219|mint:Q9JHU4|rcsb pdb:3ERR|rcsb pdb:3J1T|rcsb pdb:3J1U|rcsb pdb:3WUQ|rcsb pdb:5AYH|rcsb pdb:6RZA|rcsb pdb:6RZB|reactome:R-MMU-141444|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5663220|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8854518|reactome:R-MMU-9646399|reactome:R-MMU-9648025	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:sbED0xqQpe32T7I8ijeS3Xqlx7010090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q9ERG2	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-911729|ensembl:ENSMUSP00000013130	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:strn3_mouse(display_long)|uniprotkb:Cell cycle autoantigen SG2NA(gene name synonym)|uniprotkb:S/G2 antigen(gene name synonym)|uniprotkb:Strn3(gene name)|psi-mi:Strn3(display_short)|uniprotkb:Gs2na(gene name synonym)|uniprotkb:Sg2na(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	ensembl:ENSMUSG00000020954(gene)|ensembl:ENSMUST00000013130(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR001680(WD40 repeat)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0090443"(FAR/SIN/STRIPAK complex)|interpro:IPR013258(Striatin, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9ERG2|refseq:NP_443205.1	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:TdtwkF77kxNiBo0jtPGVLwUlxoI10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q60930	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-444578|ensembl:ENSMUSP00000022293|uniprotkb:Q78MH6|uniprotkb:Q99L98	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:vdac2_mouse(display_long)|uniprotkb:Voltage-dependent anion-selective channel protein 6(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)|uniprotkb:Vdac2(gene name)|psi-mi:Vdac2(display_short)|uniprotkb:Vdac6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_035825.1|ensembl:ENSMUSG00000021771(gene)|ensembl:ENSMUST00000022293(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:Q60930|reactome:R-MMU-5689880	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:ApSD4TVlagQ1QHePbOZw7J5rmzQ10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:E9PX29	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-16726177|ensembl:ENSMUSP00000011895	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:e9px29_mouse(display_long)|uniprotkb:Sptbn4(gene name)|psi-mi:Sptbn4(display_short)|uniprotkb:Spnb4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	ensembl:ENSMUSG00000011751(gene)|ensembl:ENSMUST00000011895(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008091"(spectrin)|go:"GO:0009566"(fertilization)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022414"(reproductive process)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0030534"(adult behavior)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043203"(axon hillock)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0051693"(actin filament capping)|go:"GO:0061337"(cardiac conduction)|go:"GO:0070852"(cell body fiber)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|rcsb pdb:6M3Q|rcsb pdb:6M3R|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6807878|go:"GO:0002028"(regulation of sodium ion transport)|refseq:NP_115999.2	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:3opwQ0kPX0QazJZ879BT5RmTr6A10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:P84078	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-2308190|uniprotkb:P10947|uniprotkb:P32889|uniprotkb:Q3THZ2|uniprotkb:Q3U849|uniprotkb:Q3UDG1|uniprotkb:Q3UF76|ensembl:ENSMUSP00000079905|ensembl:ENSMUSP00000126120	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:arf1_mouse(display_long)|uniprotkb:Arf1(gene name)|psi-mi:Arf1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_001123880.1|refseq:NP_031502.1|ensembl:ENSMUSG00000048076(gene)|ensembl:ENSMUST00000061242(transcript)|ensembl:ENSMUST00000163300(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84078|rcsb pdb:1O3Y|rcsb pdb:2J59|reactome:R-MMU-1660499|reactome:R-MMU-1660514|reactome:R-MMU-199992|reactome:R-MMU-2132295|reactome:R-MMU-432720|reactome:R-MMU-432722|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811438	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:zray9asm6VonxpuJpv0dRBspPt810090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q8JZQ2	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-3647776|ensembl:ENSMUSP00000025408	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:afg32_mouse(display_long)|uniprotkb:Afg3l2(gene name)|psi-mi:Afg3l2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_081406.1|ensembl:ENSMUSG00000024527(gene)|ensembl:ENSMUST00000025408(transcript)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005745"(m-AAA complex)|go:"GO:0006508"(proteolysis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016485"(protein processing)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0021675"(nerve development)|go:"GO:0033619"(membrane protein proteolysis)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042407"(cristae formation)|go:"GO:0042552"(myelination)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0055001"(muscle cell development)|go:"GO:0060013"(righting reflex)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000642(Peptidase M41)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005936(Peptidase M41, FtsH)|interpro:IPR011546(Peptidase M41, FtsH extracellular)|interpro:IPR027417|interpro:IPR037219|interpro:IPR041569|mint:Q8JZQ2|reactome:R-MMU-8949664	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:MDLdDol9xrpfndcy+9HZ7VW8erI10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q3ULD5	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-6877475|ensembl:ENSMUSP00000022148|uniprotkb:Q3UPS6	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:mccb_mouse(display_long)|uniprotkb:Mccc2(gene name)|psi-mi:Mccc2(display_short)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	ensembl:ENSMUSG00000021646(gene)|ensembl:ENSMUST00000022148(transcript)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q3ULD5|reactome:R-MMU-196780|reactome:R-MMU-70895|refseq:NP_084302.1	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:0q4wsAWb+zqTRNjZnCPoNabUrbA10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q9QXZ0	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-643248|intact:EBI-2658096|uniprotkb:B1ARU3|uniprotkb:Q4PLL5|uniprotkb:P97394|uniprotkb:P97395|uniprotkb:P97396	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:macf1_mouse(display_long)|uniprotkb:Actin cross-linking family 7(gene name synonym)|uniprotkb:Macf1(gene name)|psi-mi:Macf1(display_short)|uniprotkb:Acf7(gene name synonym)|uniprotkb:Aclp7(gene name synonym)|uniprotkb:Macf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR002017(Spectrin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR001101(Plectin repeat)|interpro:IPR018159|interpro:IPR001452(Src homology-3)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0042060"(wound healing)|go:"GO:0008104"(protein localization)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0150011"(regulation of neuron projection arborization)|mint:Q9QXZ0|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:niJxpkI45VTa5x73A1tuX/aLXgo10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q08189	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-11707008|uniprotkb:A1L343|uniprotkb:A2ANC3|ensembl:ENSMUSP00000105928	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:tgm3_mouse(display_long)|uniprotkb:Tgm3(gene name)|psi-mi:Tgm3(display_short)|uniprotkb:Tgase3(gene name synonym)|uniprotkb:Transglutaminase E(gene name synonym)|uniprotkb:Transglutaminase-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_033400.2|ensembl:ENSMUSG00000027401(gene)|ensembl:ENSMUST00000110299(transcript)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0001533"(cornified envelope)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031424"(keratinization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0043163"(cell envelope organization)|go:"GO:0043588"(skin development)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:Rlc2Bws2SyOa3yZUvaDb7eVm9W010090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:O08807	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-494652|uniprotkb:Q3U8E4|uniprotkb:B1AZS7|ensembl:ENSMUSP00000026328	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:prdx4_mouse(display_long)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)|uniprotkb:Prdx4(gene name)|psi-mi:Prdx4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_058044.1|refseq:NP_001300640.1|dip:DIP-34137N|ensembl:ENSMUSG00000025289(gene)|ensembl:ENSMUST00000026328(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:O08807|rcsb pdb:3VWU|rcsb pdb:3VWV|rcsb pdb:3W8J|rcsb pdb:3WGX|reactome:R-MMU-6798695	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:86EzEedrO6v5Z2dnSB2fSPaV2hc10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q9ESB3	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-20567331|uniprotkb:Q6YK32|uniprotkb:Q6YKA2|uniprotkb:Q99PS5|uniprotkb:Q99PS6	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:hrg_mouse(display_long)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym)|uniprotkb:Hrg(gene name)|psi-mi:Hrg(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	reactome:R-MMU-114608|reactome:R-MMU-75205|refseq:NP_444406.2|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|go:"GO:0001525"(angiogenesis)|go:"GO:0002839"(positive regulation of immune response to tumor cell)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0006935"(chemotaxis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015886"(heme transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0020037"(heme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031982"(vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0034395"(regulation of transcription from RNA polymerase II promoter in response to iron)|go:"GO:0036019"(endolysosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097037"(heme export)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000504"(positive regulation of blood vessel remodeling)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:1d8/1GRDzMUgvhpOya054oh13tU10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:O08677	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-738531|uniprotkb:O08676|uniprotkb:Q91XK5|uniprotkb:Q32MX7|uniprotkb:Q6S9I1	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:kng1_mouse(display_long)|uniprotkb:Kng1(gene name)|psi-mi:Kng1(display_short)|uniprotkb:Kng(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	interpro:IPR027358|refseq:NP_001095881.1|refseq:NP_075614.1|interpro:IPR002395(HMW kininogen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007596"(blood coagulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0042311"(vasodilation)|go:"GO:0062023"(collagen-containing extracellular matrix)|mint:O08677	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:b3fkbWY+mVAwNAWfKdrAYPU2dtM10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:P97742	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-20567509|uniprotkb:O35288|uniprotkb:Q80SW3|uniprotkb:Q8BP98|uniprotkb:Q8C7H8|ensembl:ENSMUSP00000025835	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:cpt1a_mouse(display_long)|uniprotkb:Carnitine O-palmitoyltransferase I, liver isoform(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase 1A(gene name synonym)|uniprotkb:Cpt1a(gene name)|psi-mi:Cpt1a(display_short)|uniprotkb:Cpt-1(gene name synonym)|uniprotkb:Cpt1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_038523.2|refseq:XP_006531717.1|refseq:XP_006531718.1|refseq:XP_006531721.1|refseq:XP_006531722.1|ensembl:ENSMUSG00000024900(gene)|ensembl:ENSMUST00000025835(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0010876"(lipid localization)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032000"(positive regulation of fatty acid beta-oxidation)|go:"GO:0042493"|go:"GO:0042755"(eating behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043279"(response to alkaloid)|go:"GO:0045471"(response to ethanol)|go:"GO:0046320"(regulation of fatty acid oxidation)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0097421"(liver regeneration)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990698"(palmitoleoyltransferase activity)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR032476|interpro:IPR039551|interpro:IPR042231|reactome:R-MMU-200425|reactome:R-MMU-5362517|go:"GO:0006641"(triglyceride metabolic process)	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:UM1IuaPnG0DqRh4AKGlI6F7xjwg10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:P23927	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:P14602	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-299023|ensembl:ENSMUSP00000005077	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q61234	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-295952|uniprotkb:Q8VEF3|ensembl:ENSMUSP00000028991	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:snta1_mouse(display_long)|uniprotkb:Snta1(gene name)|psi-mi:Snta1(display_short)|uniprotkb:Snt1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 acidic component 1(gene name synonym)|uniprotkb:Syntrophin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0051117"(ATPase binding)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028552|interpro:IPR036034|interpro:IPR041428|mint:Q61234|rcsb pdb:1QAV|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|rcsb pdb:1Z86|rcsb pdb:1Z87|rcsb pdb:2ADZ|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|rcsb pdb:2PDZ|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|rcsb pdb:4HOP|ensembl:ENSMUSG00000027488(gene)|ensembl:ENSMUST00000028991(transcript)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003117"(regulation of vasoconstriction by circulating norepinephrine)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|dip:DIP-32898N	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:ENtty34uPh1ZGRmhT4TTIM/OVpI10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:P02469	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-6662997|ensembl:ENSMUSP00000002979|ensembl:ENSMUSP00000132778|uniprotkb:E9PXZ9	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:lamb1_mouse(display_long)|uniprotkb:Lamb1(gene name)|psi-mi:Lamb1(display_short)|uniprotkb:Lamb-1(gene name synonym)|uniprotkb:Lamb1-1(gene name synonym)|uniprotkb:Laminin B1 chain(gene name synonym)|uniprotkb:Laminin-1 subunit beta(gene name synonym)|uniprotkb:Laminin-10 subunit beta(gene name synonym)|uniprotkb:Laminin-12 subunit beta(gene name synonym)|uniprotkb:Laminin-2 subunit beta(gene name synonym)|uniprotkb:Laminin-6 subunit beta(gene name synonym)|uniprotkb:Laminin-8 subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:XP_006515055.2|ensembl:ENSMUSG00000002900(gene)|ensembl:ENSMUST00000002979(transcript)|ensembl:ENSMUST00000169088(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005606"(laminin-1 complex)|go:"GO:0005607"(laminin-2 complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007566"(embryo implantation)|go:"GO:0007611"(learning or memory)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009888"(tissue development)|go:"GO:0016477"(cell migration)|go:"GO:0019899"(enzyme binding)|go:"GO:0021812"(neuronal-glial interaction involved in cerebral cortex radial glia guided migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031175"(neuron projection development)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042476"(odontogenesis)|go:"GO:0043208"(glycosphingolipid binding)|go:"GO:0043256"(laminin complex)|go:"GO:0043257"(laminin-8 complex)|go:"GO:0043259"(laminin-10 complex)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-3000157|reactome:R-MMU-381426|reactome:R-MMU-8874081|go:"GO:0070831"(basement membrane assembly)|reactome:R-MMU-8957275|interpro:IPR000742(EGF-like, type 3)|interpro:IPR002049(EGF-like, laminin)|interpro:IPR008211(Laminin, N-terminal)|interpro:IPR013015(Laminin IV)|mint:P02469|rcsb pdb:4AQS|rcsb pdb:5MC9|refseq:XP_006515056.1	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:cUuVqY2JMeRrS9sDYudPy7hSIL010090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q99MR8	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-773469|uniprotkb:Q3TGU0|uniprotkb:Q9D8R2|ensembl:ENSMUSP00000029259	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:mcca_mouse(display_long)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym)|uniprotkb:Mccc1(gene name)|psi-mi:Mccc1(display_short)|uniprotkb:Mcca(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_076133.3|ensembl:ENSMUSG00000027709(gene)|ensembl:ENSMUST00000029259(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q99MR8|reactome:R-MMU-196780|reactome:R-MMU-70895	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:SziuYdcOx+maKy71pNxoKql1HGI10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q80VP2	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-20567308|uniprotkb:Q8BK23|ensembl:ENSMUSP00000045827	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:spat7_mouse(display_long)|uniprotkb:Spata7(gene name)|psi-mi:Spata7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_849245.2|refseq:XP_011242281.1|ensembl:ENSMUSG00000021007(gene)|ensembl:ENSMUST00000048402(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|go:"GO:1903621"(protein localization to photoreceptor connecting cilium)|interpro:IPR029357	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:pi0BcVpwFuv5yjL0fmGfW1jtavc10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q9R1P0	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-772804|uniprotkb:Q3THT1|ensembl:ENSMUSP00000034848	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:psa4_mouse(display_long)|uniprotkb:Proteasome component C9(gene name synonym)|uniprotkb:Macropain subunit C9(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex subunit C9(gene name synonym)|uniprotkb:Proteasome subunit L(gene name synonym)|uniprotkb:Psma4(gene name)|psi-mi:Psma4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	refseq:NP_036096.1|refseq:XP_006511261.1|ensembl:ENSMUSG00000032301(gene)|ensembl:ENSMUST00000034848(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023332|interpro:IPR029055|interpro:IPR034647|mint:Q9R1P0|rcsb pdb:3UNB|rcsb pdb:3UNE|rcsb pdb:3UNF|rcsb pdb:3UNH|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:6Dp8VODK8RbwARcOjjpMbvCN1pU10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:O70468	uniprotkb:Q91ZE6	intact:EBI-8347074|uniprotkb:O88997|intact:MINT-4102925	intact:EBI-20568128|ensembl:ENSMUSP00000132807	psi-mi:mypc3_mouse(display_long)|uniprotkb:Mybpc3(gene name)|psi-mi:Mybpc3(display_short)|uniprotkb:C-protein, cardiac muscle isoform(gene name synonym)	psi-mi:q91ze6_mouse(display_long)|uniprotkb:Sptbn4(gene name)|psi-mi:Sptbn4(display_short)|uniprotkb:Spnb4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Lundby et al. (2014)	pubmed:24952909|imex:IM-26422	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-20567507|imex:IM-26422-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	dip:DIP-48624N|mint:O70468|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030017"(sarcomere)|go:"GO:0031034"(myosin filament assembly)|go:"GO:0031672"(A band)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0097512"(cardiac myofibril)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR040849|rcsb pdb:4EDQ|reactome:R-MMU-390522|interpro:IPR036116	ensembl:ENSMUSG00000011751(gene)|ensembl:ENSMUST00000172269(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008091"(spectrin)|go:"GO:0009566"(fertilization)|go:"GO:0010459"(negative regulation of heart rate)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0022414"(reproductive process)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0030534"(adult behavior)|go:"GO:0033135"(regulation of peptidyl-serine phosphorylation)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034613"(cellular protein localization)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043203"(axon hillock)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0051693"(actin filament capping)|go:"GO:0061337"(cardiac conduction)|go:"GO:0070852"(cell body fiber)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681	-	comment:mint|function:Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role	-	figure legend:Table S13|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-heart)|taxid:10090(Mus musculus heart [Cardiac; Cardiac tissue])	-	2018/05/25	2018/05/31	rogid:vI2kpFA8OvFOUUaWDlX5bEeTjZY10090	rogid:H+/lGGbApnCakqKJj+DT0+pXnXs10090	rigid:KLatnavUXkVwjqAKi3IN9tom0Ng	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)