#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q92783	uniprotkb:O14964	intact:EBI-752333|uniprotkb:Q8N6D9|uniprotkb:B0YJ99|intact:EBI-3447129|uniprotkb:D3DRU5|intact:EBI-28983444|ensembl:ENSP00000366746	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	psi-mi:stam1_human(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763617|imex:IM-11779-1|dip:DIP-102553E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003464.1|ensembl:ENSP00000366746|dip:DIP-37761N|go:"GO:0043328"(protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR035657|interpro:IPR036028|mint:Q92783|rcsb pdb:2L0A|rcsb pdb:3F1I|rcsb pdb:3LDZ|reactome:R-HSA-182971|reactome:R-HSA-5689901|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016236"(macroautophagy)|go:"GO:0031901"(early endosome membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2017/08/06	2017/08/10	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rigid:6q+lzdARrb856d7pXDDY4x9YKy0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O14964	uniprotkb:Q92783-1	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-15763634|ensembl:ENSP00000366746	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:"MI:0038"(dynamic light scattering)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763679|imex:IM-11779-4|dip:DIP-102553E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rigid:6q+lzdARrb856d7pXDDY4x9YKy0	false	binding-associated region:1-557	binding-associated region:10-390	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14964	uniprotkb:Q92783-1	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-15763634|ensembl:ENSP00000366746	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763658|imex:IM-11779-3|dip:DIP-102553E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rigid:6q+lzdARrb856d7pXDDY4x9YKy0	false	binding-associated region:404-501	binding-associated region:301-377	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99LI8	uniprotkb:Q92783-1	intact:EBI-2119135|uniprotkb:Q61691|uniprotkb:Q8BQW3|ensembl:ENSMUSP00000101811	intact:EBI-15763634|ensembl:ENSP00000366746	psi-mi:hgs_mouse(display_long)|uniprotkb:Hgs(gene name)|psi-mi:Hgs(display_short)|uniprotkb:Hrs(gene name synonym)	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:"MI:0038"(dynamic light scattering)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763640|imex:IM-11779-2|dip:DIP-88900E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001152800.1|refseq:NP_032270.3|dip:DIP-29102N|ensembl:ENSMUSG00000025793(gene)|ensembl:ENSMUST00000106205(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|reactome:R-MMU-182971|reactome:R-MMU-432720|reactome:R-MMU-5689880|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|reactome:R-MMU-9706019	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/06	2017/08/10	rogid:FS8KSHYryqJPQyo6wRWGNz86/kw10090	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rigid:TnOL0pZmhK06FPaULHOdvGu36SY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14964	uniprotkb:Q92783-1	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-15763634|ensembl:ENSP00000366746	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:"MI:0067"(light scattering)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763700|imex:IM-11779-5|dip:DIP-102553E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rigid:6q+lzdARrb856d7pXDDY4x9YKy0	false	binding-associated region:1-557	binding-associated region:10-390	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99LI8	uniprotkb:Q92783-1	intact:EBI-2119135|uniprotkb:Q61691|uniprotkb:Q8BQW3|ensembl:ENSMUSP00000101811	intact:EBI-15763634|ensembl:ENSP00000366746	psi-mi:hgs_mouse(display_long)|uniprotkb:Hgs(gene name)|psi-mi:Hgs(display_short)|uniprotkb:Hrs(gene name synonym)	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:"MI:0067"(light scattering)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763721|imex:IM-11779-6|dip:DIP-88900E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001152800.1|refseq:NP_032270.3|dip:DIP-29102N|ensembl:ENSMUSG00000025793(gene)|ensembl:ENSMUST00000106205(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|reactome:R-MMU-182971|reactome:R-MMU-432720|reactome:R-MMU-5689880|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|reactome:R-MMU-9706019	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/06	2017/08/10	rogid:FS8KSHYryqJPQyo6wRWGNz86/kw10090	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rigid:TnOL0pZmhK06FPaULHOdvGu36SY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14964	uniprotkb:Q92783-1	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-15763634|ensembl:ENSP00000366746	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763799|imex:IM-11779-10|dip:DIP-102553E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rigid:6q+lzdARrb856d7pXDDY4x9YKy0	false	sufficient binding region:398-514	sufficient binding region:282-387	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q92783-1	uniprotkb:P62990	intact:EBI-15763634|ensembl:ENSP00000366746	intact:EBI-413053|uniprotkb:Q28170|uniprotkb:Q29120|uniprotkb:O97577|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P80169|uniprotkb:Q01235|uniprotkb:Q24K23|uniprotkb:Q28169|uniprotkb:Q3ZCE3|uniprotkb:Q862C1|uniprotkb:Q862F4|uniprotkb:Q862M4|uniprotkb:Q862T5|uniprotkb:Q862X8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q3T0V5|dip:DIP-29049N	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:ubiq_bovin(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short)|uniprotkb:UBC(gene name)|psi-mi:UBC(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)")	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763776|imex:IM-11779-9|dip:DIP-102554E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	interpro:IPR000626(Ubiquitin)|refseq:NP_001069831.1|refseq:NP_777203.1|refseq:NP_776558.1|rcsb pdb:2QHO|rcsb pdb:2ZCC|ensembl:ENSBTAG00000015473|ensembl:ENSBTAG00000017246|rcsb pdb:1E0Q|rcsb pdb:2HD5|rcsb pdb:2OOB|interpro:IPR019954|interpro:IPR019956|interpro:IPR019955|rcsb pdb:3H1U|go:"GO:0005515"(protein binding)|go:"GO:0030528"(obsolete transcription regulator activity)|go:"GO:0045941"|go:"GO:0016567"(protein ubiquitination)|ensembl:ENSBTAG00000007737|rcsb pdb:1AAR|rcsb pdb:1P3Q|rcsb pdb:1UZX|rcsb pdb:1V80|rcsb pdb:1V81|rcsb pdb:1WR6|rcsb pdb:1WRD|rcsb pdb:1YD8|rcsb pdb:2C7M|rcsb pdb:2C7N|rcsb pdb:2D3G|rcsb pdb:2DX5|rcsb pdb:2FID|rcsb pdb:2FIF|go:"GO:0005634"(nucleus)|ipi:IPI00687665|rcsb pdb:2WWZ|rcsb pdb:2WX0|rcsb pdb:2WX1	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2017/08/06	2017/08/15	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rogid:dobaeYpohKyDSnm4fBbcy0ZbYwM9913	rigid:lyfe7xdIRK/B8II5vNgK3WseWe0	false	binding-associated region:1-143|his tag:?-?	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O14964	uniprotkb:Q92783-1	intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106	intact:EBI-15763634|ensembl:ENSP00000366746	psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym)	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763755|imex:IM-11779-8|dip:DIP-102553E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:562(ecolx)|taxid:562(Escherichia coli)	-	2017/08/06	2017/08/10	rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rigid:6q+lzdARrb856d7pXDDY4x9YKy0	false	binding-associated region:1-557	binding-associated region:10-390	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99LI8	uniprotkb:Q92783-1	intact:EBI-2119135|uniprotkb:Q61691|uniprotkb:Q8BQW3|ensembl:ENSMUSP00000101811	intact:EBI-15763634|ensembl:ENSP00000366746	psi-mi:hgs_mouse(display_long)|uniprotkb:Hgs(gene name)|psi-mi:Hgs(display_short)|uniprotkb:Hrs(gene name synonym)	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763738|imex:IM-11779-7|dip:DIP-88900E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001152800.1|refseq:NP_032270.3|dip:DIP-29102N|ensembl:ENSMUSG00000025793(gene)|ensembl:ENSMUST00000106205(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|reactome:R-MMU-182971|reactome:R-MMU-432720|reactome:R-MMU-5689880|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|reactome:R-MMU-9706019	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/06	2017/08/10	rogid:FS8KSHYryqJPQyo6wRWGNz86/kw10090	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rigid:TnOL0pZmhK06FPaULHOdvGu36SY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q99LI8	uniprotkb:Q92783-1	intact:EBI-2119135|uniprotkb:Q61691|uniprotkb:Q8BQW3|ensembl:ENSMUSP00000101811	intact:EBI-15763634|ensembl:ENSP00000366746	psi-mi:hgs_mouse(display_long)|uniprotkb:Hgs(gene name)|psi-mi:Hgs(display_short)|uniprotkb:Hrs(gene name synonym)	psi-mi:q92783-1(display_long)|uniprotkb:STAM(gene name)|psi-mi:STAM(display_short)|uniprotkb:STAM1(gene name synonym)	psi-mi:"MI:0028"(cosedimentation in solution)	Ren et al. (2009)	pubmed:19278655|doi:10.1016/j.str.2009.01.012|imex:IM-11779	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-15763820|imex:IM-11779-11|dip:DIP-88900E	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001152800.1|refseq:NP_032270.3|dip:DIP-29102N|ensembl:ENSMUSG00000025793(gene)|ensembl:ENSMUST00000106205(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0140036"(ubiquitin-dependent protein binding)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|reactome:R-MMU-182971|reactome:R-MMU-432720|reactome:R-MMU-5689880|reactome:R-MMU-6807004|reactome:R-MMU-8856825|reactome:R-MMU-8856828|reactome:R-MMU-9013420|reactome:R-MMU-917729|reactome:R-MMU-9706019	intact:EBI-752333(isoform-parent)|ensembl:ENSG00000136738(gene)|ensembl:ENST00000377524(transcript)	psi-mi:"MI:0465"(dip)	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7111(trini)|taxid:7111("Trichoplusia ni (Cabbage looper)")	-	2017/08/06	2017/08/10	rogid:FS8KSHYryqJPQyo6wRWGNz86/kw10090	rogid:+XzmsTsMqOFTM5SM1fuVB+0UzeQ9606	rigid:TnOL0pZmhK06FPaULHOdvGu36SY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)