#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q96FW1	uniprotkb:P56270	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1809742|uniprotkb:A8QJL9|uniprotkb:Q15703|uniprotkb:Q99443|uniprotkb:H3BQD6|uniprotkb:G5E927|uniprotkb:Q8NFN7|uniprotkb:C6G496|ensembl:ENSP00000313362	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:maz_human(display_long)|uniprotkb:Transcription factor Zif87(gene name synonym)|uniprotkb:Zinc finger protein 801(gene name synonym)|uniprotkb:MAZ(gene name)|psi-mi:MAZ(display_short)|uniprotkb:Purine-binding transcription factor(gene name synonym)|uniprotkb:Pur-1(gene name synonym)|uniprotkb:ZF87(gene name synonym)|uniprotkb:ZNF801(gene name synonym)|uniprotkb:Serum amyloid A-activating factor-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002374.2|refseq:NP_001036004.1|refseq:NP_001263205.1|refseq:NP_001263204.1|ensembl:ENSG00000103495(gene)|ensembl:ENST00000322945(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P56270	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:zuCDXhF2wr8gmTyjBNse9kVUqSw9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P18754	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-992720|uniprotkb:Q16269|uniprotkb:Q6NT97|ensembl:ENSP00000362939|ensembl:ENSP00000381931|ensembl:ENSP00000508074|ensembl:ENSP00000362938	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rcc1_human(display_long)|uniprotkb:Chromosome condensation protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein(gene name synonym)|uniprotkb:RCC1(gene name)|psi-mi:RCC1(display_short)|uniprotkb:CHC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001041659.1|refseq:NP_001041660.1|refseq:NP_001041664.1|refseq:NP_001260.1|dip:DIP-35416N|ensembl:ENSG00000180198(gene)|ensembl:ENST00000373832(transcript)|ensembl:ENST00000373833(transcript)|ensembl:ENST00000398958(transcript)|ensembl:ENST00000683442(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016032"(viral process)|rcsb pdb:5E1B|rcsb pdb:5E1D|rcsb pdb:5E1M|rcsb pdb:5E1O|rcsb pdb:5E2A|go:"GO:0031267"(small GTPase binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031492"(nucleosomal DNA binding)|rcsb pdb:5E2B|rcsb pdb:5TBK|rcsb pdb:6DUB|reactome:R-HSA-165054|go:"GO:0031965"(nuclear membrane)|reactome:R-HSA-180746|reactome:R-HSA-9615933|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:P18754|rcsb pdb:1A12|rcsb pdb:1I2M	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:/gP2xQp6fUffHTXpXvs8eb5YJ209606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P14635	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-495332|uniprotkb:A8K066|uniprotkb:Q5TZP9|ensembl:ENSP00000256442	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ccnb1_human(display_long)|uniprotkb:CCNB1(gene name)|psi-mi:CCNB1(display_short)|uniprotkb:CCNB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_114172.1|dip:DIP-59N|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042493"|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046680"(response to DDT)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048565"(digestive tract development)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|ensembl:ENSG00000134057(gene)|ensembl:ENST00000256442(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005113"(patched binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|go:"GO:2000775"(obsolete histone H3-S10 phosphorylation involved in chromosome condensation)|interpro:IPR004367(Cyclin, C-terminal)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071283"("cellular response to iron(III) ion")|interpro:IPR039361|mint:P14635|rcsb pdb:2B9R|rcsb pdb:2JGZ|rcsb pdb:4Y72|rcsb pdb:4YC3|go:"GO:0071398"(cellular response to fatty acid)|rcsb pdb:5HQ0|go:"GO:0071407"(cellular response to organic cyclic compound)|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|reactome:R-HSA-113507|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174048|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|go:"GO:0071456"(cellular response to hypoxia)|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-4419969|reactome:R-HSA-6804114|reactome:R-HSA-68875|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8878166|reactome:R-HSA-8852276	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:WCQWqI2kWZfatq4L2DC0hm26Ix09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y5M8	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355393|uniprotkb:Q8N2D8|uniprotkb:Q6P595|ensembl:ENSP00000418401|ensembl:ENSP00000503923	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:srprb_human(display_long)|uniprotkb:SRPRB(gene name)|psi-mi:SRPRB(display_short)|uniprotkb:PSEC0230(orf name)|uniprotkb:Protein APMCF1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_067026.3|ensembl:ENSG00000144867(gene)|ensembl:ENST00000466490(transcript)|ensembl:ENST00000678299(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|mint:Q9Y5M8|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|dip:DIP-50218N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pHUdnCvOhMRYIJg//OJ+SlCard49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y5A9	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2878081|uniprotkb:B4E1G7|uniprotkb:A6NKG4|uniprotkb:Q5VSZ9|uniprotkb:Q8TDH0|uniprotkb:Q9BUJ5|uniprotkb:A8K966|uniprotkb:D3DPM8|ensembl:ENSP00000362918|ensembl:ENSP00000444660	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ythd2_human(display_long)|uniprotkb:HGRG8(gene name synonym)|uniprotkb:CLL-associated antigen KW-14(gene name synonym)|uniprotkb:High-glucose-regulated protein 8(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-2(gene name synonym)|uniprotkb:YTHDF2(gene name)|psi-mi:YTHDF2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001166299.1|refseq:NP_001166599.1|refseq:NP_057342.2|ensembl:ENSG00000198492(gene)|ensembl:ENST00000373812(transcript)|ensembl:ENST00000542507(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007049"(cell cycle)|go:"GO:0007276"(gamete generation)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045087"(innate immune response)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070925"(organelle assembly)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR007275(YT521-B-like protein)|mint:Q9Y5A9|rcsb pdb:4RDO|rcsb pdb:4WQN|rcsb pdb:4RDN	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:PF4C2t/728HqnrTyBQDJydH0G709606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y383	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y314	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051889|uniprotkb:Q96FD2|ensembl:ENSP00000470034	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:nosip_human(display_long)|uniprotkb:eNOS-interacting protein(gene name synonym)|uniprotkb:NOSIP(gene name)|psi-mi:NOSIP(display_short)|uniprotkb:CGI-25(orf name)|uniprotkb:E3 ubiquitin-protein ligase NOSIP(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NOSIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001257889.1|refseq:NP_057037.1|ensembl:ENSG00000142546(gene)|ensembl:ENST00000596358(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016818(Nitric oxide synthase-interacting)|interpro:IPR031790|reactome:R-HSA-203754|refseq:XP_016882340.1|refseq:XP_016882341.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:vC1sjYkWe4QjRlwCJ3C5+EB8PcA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y266	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-357298|ensembl:ENSP00000319664|uniprotkb:Q5QP31|uniprotkb:Q5QP35|uniprotkb:Q9H0N2|uniprotkb:Q9Y2B6|intact:EBI-2555945	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:nudc_human(display_long)|uniprotkb:NUDC(gene name)|psi-mi:NUDC(display_short)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000090273(gene)|ensembl:ENST00000321265(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:Q9Y266|rcsb pdb:3QOR|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0007080"(mitotic metaphase plate congression)|reactome:R-HSA-9696270|refseq:NP_006591.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:e1Q+/+VhG73ljCc3+ibG+RZNQUM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UNX3	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2949703|ensembl:ENSP00000265100|ensembl:ENSP00000428177|ensembl:ENSP00000428223|ensembl:ENSP00000430147|uniprotkb:B3KY82|uniprotkb:D3DQM0	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rl26l_human(display_long)|uniprotkb:RPL26L1(gene name)|psi-mi:RPL26L1(display_short)|uniprotkb:RPL26P1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL24-like 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000037241(gene)|ensembl:ENST00000265100(transcript)|ensembl:ENST00000519239(transcript)|ensembl:ENST00000519974(transcript)|ensembl:ENST00000521476(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q9UNX3|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-2408557|refseq:NP_057177.1|refseq:XP_011532867.1|refseq:NP_001304909.1|refseq:NP_001304910.1|refseq:NP_001304911.1|refseq:XP_016865008.1|refseq:XP_016865009.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:dny/DWK4MvWD3FUJvW5+KGI3iJI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UNF1	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-725832|uniprotkb:O76058|uniprotkb:Q5BJF3|uniprotkb:Q8NAL6|uniprotkb:Q9H218|uniprotkb:Q9P0U9|uniprotkb:A6NMX0|uniprotkb:Q9UM52|ensembl:ENSP00000218439|ensembl:ENSP00000364193|ensembl:ENSP00000364198|ensembl:ENSP00000364209|ensembl:ENSP00000379526	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:magd2_human(display_long)|uniprotkb:MAGE-D2 antigen(gene name synonym)|uniprotkb:Breast cancer-associated gene 1 protein(gene name synonym)|uniprotkb:11B6(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated protein JCL-1(gene name synonym)|uniprotkb:MAGED2(gene name)|psi-mi:MAGED2(display_short)|uniprotkb:BCG1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_055414.2|refseq:NP_803182.1|refseq:NP_957516.1|ensembl:ENSG00000102316(gene)|ensembl:ENST00000218439(transcript)|ensembl:ENST00000375053(transcript)|ensembl:ENST00000375058(transcript)|ensembl:ENST00000375068(transcript)|ensembl:ENST00000396224(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007565"(female pregnancy)|go:"GO:0016020"(membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0070294"(renal sodium ion absorption)|interpro:IPR002190(MAGE protein)|interpro:IPR028810|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9UNF1|reactome:R-HSA-114608|dip:DIP-50722N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fXavezmKy58aGuVgzvDYjwNw3B89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UNE7	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9ULJ3	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051048|intact:EBI-1774011|uniprotkb:Q5R2W1|uniprotkb:Q5R2W2|uniprotkb:Q6P4R0|ensembl:ENSP00000308759|ensembl:ENSP00000381512|ensembl:ENSP00000381523	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:zbt21_human(display_long)|uniprotkb:ZBTB21(gene name)|psi-mi:ZBTB21(display_short)|uniprotkb:KIAA1227(gene name synonym)|uniprotkb:ZNF295(gene name synonym)|uniprotkb:Zinc finger protein 295(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001091872.1|refseq:NP_065778.3|refseq:XP_011527890.1|refseq:XP_011527892.1|refseq:NP_001307658.1|refseq:NP_001307660.1|refseq:XP_016883849.1|refseq:XP_016883850.1|refseq:NP_001091873.1|refseq:XP_005261178.1|ensembl:ENST00000310826(transcript)|ensembl:ENST00000398499(transcript)|ensembl:ENST00000398511(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0031208"(POZ domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041011|rcsb pdb:1WJP|ensembl:ENSG00000173276(gene)|ensembl:ENSP00000308759|ensembl:ENSP00000381512|ensembl:ENST00000398505|ensembl:ENSP00000381517|ensembl:ENSP00000381523	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:0yEEz3zJHqnDrVQdftkyVhL6PKU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UJS0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UHD1	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9P258	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-352547|uniprotkb:Q8IVL9|uniprotkb:Q9BSN6|uniprotkb:Q9NPV8|ensembl:ENSP00000364582|ensembl:ENSP00000364585|ensembl:ENSP00000486099|ensembl:ENSP00000486447	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rcc2_human(display_long)|uniprotkb:RCC2(gene name)|psi-mi:RCC2(display_short)|uniprotkb:KIAA1470(gene name synonym)|uniprotkb:TD60(gene name synonym)|uniprotkb:Telophase disk protein of 60 kDa(gene name synonym)|uniprotkb:RCC1-like protein TD-60(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001129676.1|refseq:NP_061185.1|ensembl:ENSG00000179051(gene)|ensembl:ENSG00000281540(gene)|ensembl:ENST00000375433(transcript)|ensembl:ENST00000375436(transcript)|ensembl:ENST00000628984(transcript)|ensembl:ENST00000631021(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051301"(cell division)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072356"(chromosome passenger complex localization to kinetochore)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR028641|mint:Q9P258|rcsb pdb:5GWN|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:z9+0avftBLs4Q3ODFHLEmJtd57A9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NXS2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052839|uniprotkb:Q53HE4|uniprotkb:Q96F74|ensembl:ENSP00000012049	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:qpctl_human(display_long)|uniprotkb:Golgi-resident glutaminyl-peptide cyclotransferase(gene name synonym)|uniprotkb:isoQC(gene name synonym)|uniprotkb:QPCTL(gene name)|psi-mi:QPCTL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001156849.1|refseq:NP_060129.2|ensembl:ENSG00000011478(gene)|ensembl:ENST00000012049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016603"(glutaminyl-peptide cyclotransferase activity)|go:"GO:0017186"(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase)|interpro:IPR037457|interpro:IPR040234|rcsb pdb:3PB4|rcsb pdb:3PB6|rcsb pdb:3PB7|rcsb pdb:3PB8|rcsb pdb:3PB9|interpro:IPR007484(Peptidase M28)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:J4CsQuJYRh/8S2KDQQGzZh3Mra89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NWT6	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NSD9	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-353803|uniprotkb:B4DFM0|uniprotkb:O95708|uniprotkb:Q9NZZ6|uniprotkb:Q4ZFX1|uniprotkb:Q57ZJ5|ensembl:ENSP00000281828	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:syfb_human(display_long)|uniprotkb:FARSB(gene name)|psi-mi:FARSB(display_short)|uniprotkb:FARSLB(gene name synonym)|uniprotkb:FRSB(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:HSPC173(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005678.3|refseq:XP_006712232.1|refseq:XP_011508768.1|ensembl:ENSG00000116120(gene)|ensembl:ENST00000281828(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|interpro:IPR040659|interpro:IPR041616|rcsb pdb:3L4G|reactome:R-HSA-379716|refseq:XP_016858599.1|dip:DIP-32869N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:YgMUMEiw+jAUaDK5KomMWi66vn09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NS69	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1047508|intact:EBI-1180569|ensembl:ENSP00000216034	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tom22_human(display_long)|uniprotkb:TOMM22(gene name)|psi-mi:TOMM22(display_short)|uniprotkb:TOM22(gene name synonym)|uniprotkb:Translocase of outer membrane 22 kDa subunit homolog(gene name synonym)|uniprotkb:1C9-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_064628.1|ensembl:ENSG00000100216(gene)|ensembl:ENST00000216034(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR005683(Mitochondrial import translocase, subunit Tom22)|mint:Q9NS69|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:DI3BGFSB04B1/mMHJsBpOsCxrYk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NPF4	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1056510|uniprotkb:Q6IAC3|ensembl:ENSP00000206542	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:osgep_human(display_long)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP"(gene name synonym)|uniprotkb:OSGEP(gene name)|psi-mi:OSGEP(display_short)|uniprotkb:GCPL1(gene name synonym)|uniprotkb:O-sialoglycoprotein endopeptidase(gene name synonym)|uniprotkb:tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP(gene name synonym)|uniprotkb:N6-L-threonylcarbamoyladenine synthase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_060277.1|ensembl:ENSG00000092094(gene)|ensembl:ENST00000206542(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0046872"(metal ion binding)|go:"GO:0061711"("N(6)-L-threonylcarbamoyladenine synthase activity")|interpro:IPR000905(Peptidase M22, glycoprotease)|interpro:IPR017860|interpro:IPR017861|interpro:IPR034680|interpro:IPR043129|mint:Q9NPF4|rcsb pdb:6GWJ|reactome:R-HSA-6782315	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:gdWaUekKJ7WFXfPlaleW9Dpmsi89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9HCC0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9HAC8	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-745871|uniprotkb:Q53HI3|uniprotkb:D3DR57|ensembl:ENSP00000359698	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ubtd1_human(display_long)|uniprotkb:UBTD1(gene name)|psi-mi:UBTD1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_079230.1|ensembl:ENSG00000165886(gene)|ensembl:ENST00000370664(transcript)|interpro:IPR000626(Ubiquitin)|interpro:IPR019956|interpro:IPR029071|interpro:IPR032752|interpro:IPR038169|interpro:IPR039869	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:P3QDDjw2RjE5kaJgtb5z6/Kmroc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9H5V9	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1053419|uniprotkb:A8MPX7|uniprotkb:B4DQN2|uniprotkb:F5GWL7|uniprotkb:O43351|uniprotkb:D3DWH9|ensembl:ENSP00000494123	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:steep_human(display_long)|uniprotkb:STEEP1(gene name)|psi-mi:STEEP1(display_short)|uniprotkb:CXorf56(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001164040.1|refseq:NP_001164041.1|refseq:NP_071384.1|ensembl:ENSG00000018610(gene)|ensembl:ENST00000644802(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0044297"(cell body)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR029704	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:24LR5Wy5GnADosh247l7Yqfr4aQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9H0C8	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2620298|uniprotkb:B3KM39|ensembl:ENSP00000254654	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ilkap_human(display_long)|uniprotkb:ILKAP(gene name)|psi-mi:ILKAP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_110395.1|ensembl:ENSG00000132323(gene)|ensembl:ENST00000254654(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q9H0C8	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:iKH8FvITcNnqKYK8zIsijGhZllM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9BQ61	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-744881|ensembl:ENSP00000242784	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:trir_human(display_long)|uniprotkb:TRIR(gene name)|psi-mi:TRIR(display_short)|uniprotkb:C19orf43(gene name synonym)|uniprotkb:Exoribonuclease TRIR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_076943.1|ensembl:ENSG00000123144(gene)|ensembl:ENST00000242784(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR038838|mint:Q9BQ61|refseq:NP_001316667.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8oDbNDhz5798Vmd+iPuLCh14ia09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q99615	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-357552|ensembl:ENSP00000406463|uniprotkb:Q7Z784	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dnjc7_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)|uniprotkb:TPR2(gene name synonym)|uniprotkb:TTC2(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000168259(gene)|ensembl:ENST00000457167(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR036869|reactome:R-HSA-3371453|refseq:NP_003306.3|refseq:XP_011523469.1|refseq:XP_011523470.1|refseq:XP_011523471.1|refseq:NP_001138238.1|refseq:XP_016880483.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:eZ1/nlVA9bOU/N3yrJ3pWrnM1P09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96LR5	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96IX5	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-954033|ensembl:ENSP00000311245|ensembl:ENSP00000337705|ensembl:ENSP00000358826|ensembl:ENSP00000358830|ensembl:ENSP00000358840|uniprotkb:B2R4N2|uniprotkb:D3DR92	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:atpmk_human(display_long)|uniprotkb:ATP5MK(gene name)|psi-mi:ATP5MK(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:ATP5MD(gene name synonym)|uniprotkb:DAPIT(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:HCV F-transactivated protein 2(gene name synonym)|uniprotkb:HCVFTP2(gene name synonym)|uniprotkb:USMG5(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:PD04912(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000173915(gene)|ensembl:ENST00000309579(transcript)|ensembl:ENST00000337003(transcript)|ensembl:ENST00000369811(transcript)|ensembl:ENST00000369815(transcript)|ensembl:ENST00000369825(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|mint:Q96IX5|refseq:NP_001193355.1|refseq:NP_001193356.1|refseq:NP_116136.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7ClNWlgeH39kD7E6oiQdkuj7Hag9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96H79	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-3050460|ensembl:ENSP00000275766|uniprotkb:Q8WUD9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:zcchl_human(display_long)|uniprotkb:ZC3HAV1L(gene name)|psi-mi:ZC3HAV1L(display_short)|uniprotkb:C7orf39(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000146858(gene)|ensembl:ENST00000275766(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR026693|interpro:IPR036388|interpro:IPR041360|refseq:NP_542391.2	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:2usjPyQ0uIzX1ZEleVqyaqcCtko9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96CX2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358358|ensembl:ENSP00000366694	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96C01	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-373319|uniprotkb:Q96SS3|ensembl:ENSP00000037869	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:f136a_human(display_long)|uniprotkb:FAM136A(gene name)|psi-mi:FAM136A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_116211.2|ensembl:ENSG00000035141(gene)|ensembl:ENST00000037869(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR008560(Protein of unknown function DUF842, eukaryotic)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:i9TSWgN6JC8fuAcFrlTU3IKBDHE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96B02	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q969T4	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8WWK9	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1221087|uniprotkb:Q9HC49|uniprotkb:Q9NVG4|uniprotkb:A2BDE0|uniprotkb:A5YM58|uniprotkb:Q3KRA5|uniprotkb:Q5VXB4|uniprotkb:Q8IWV5|uniprotkb:Q8IWV6|uniprotkb:Q96FH9|uniprotkb:Q9H012|uniprotkb:Q9H0D0|uniprotkb:Q9H988|uniprotkb:B4DR35|uniprotkb:E9PD90|intact:EBI-11054734|ensembl:ENSP00000367276	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ckap2_human(display_long)|uniprotkb:CKAP2(gene name)|psi-mi:CKAP2(display_short)|uniprotkb:LB1(gene name synonym)|uniprotkb:TMAP(gene name synonym)|uniprotkb:Tumor- and microtubule-associated protein(gene name synonym)|uniprotkb:CTCL tumor antigen se20-10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001273615.1|refseq:NP_001273616.1|refseq:NP_001091995.1|refseq:NP_060674.3|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR026165|interpro:IPR029197|mint:Q8WWK9|ensembl:ENSG00000136108(gene)|ensembl:ENST00000378037(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:17/ce51AUyDvCpdnm50uT/LSY7w9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8WWC4	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8WVK2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2512550|ensembl:ENSP00000244227|ensembl:ENSP00000395144|uniprotkb:Q15410|intact:EBI-2557655	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:snr27_human(display_long)|uniprotkb:SNRNP27(gene name)|psi-mi:SNRNP27(display_short)|uniprotkb:U4/U6.U5 tri-snRNP-associated protein 3(gene name synonym)|uniprotkb:U4/U6.U5 tri-snRNP-associated 27 kDa protein(gene name synonym)|uniprotkb:Nucleic acid-binding protein RY-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000124380(gene)|ensembl:ENST00000244227(transcript)|ensembl:ENST00000450162(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR013957(Protein of unknown function DUF1777)|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|refseq:NP_006848.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:wSOfld20fuDA9ZN9vDXLilFmmSs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8TA86	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-630339|ensembl:ENSP00000297157	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rp9_human(display_long)|uniprotkb:Pim-1-associated protein(gene name synonym)|uniprotkb:RP9(gene name)|psi-mi:RP9(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_976033.1|ensembl:ENSG00000164610(gene)|ensembl:ENST00000297157(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050890"(cognition)|interpro:IPR034585	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:aLu5MPtPUaFvJYBLKJ+ObI4c0OQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8NE71	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-720571|uniprotkb:A2BF75|uniprotkb:O14897|uniprotkb:Q69YP6|ensembl:ENSP00000313603|ensembl:ENSP00000373082|ensembl:ENSP00000389065|ensembl:ENSP00000411327|ensembl:ENSP00000412553|ensembl:ENSP00000413319|ensembl:ENSP00000414373	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:abcf1_human(display_long)|uniprotkb:ATP-binding cassette 50(gene name synonym)|uniprotkb:TNF-alpha-stimulated ABC protein(gene name synonym)|uniprotkb:ABCF1(gene name)|psi-mi:ABCF1(display_short)|uniprotkb:ABC50(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001020262.1|refseq:NP_001081.1|dip:DIP-50666N|ensembl:ENSG00000204574(gene)|ensembl:ENSG00000206490(gene)|ensembl:ENSG00000225989(gene)|ensembl:ENSG00000231129(gene)|ensembl:ENSG00000232169(gene)|ensembl:ENSG00000236149(gene)|ensembl:ENSG00000236342(gene)|ensembl:ENST00000326195(transcript)|ensembl:ENST00000383588(transcript)|ensembl:ENST00000419893(transcript)|ensembl:ENST00000423247(transcript)|ensembl:ENST00000426219(transcript)|ensembl:ENST00000457078(transcript)|ensembl:ENST00000457111(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008494"(translation activator activity)|go:"GO:0016020"(membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|mint:Q8NE71|rcsb pdb:5ZXD|reactome:R-HSA-382556	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:DdEbnAZo4bv75DRSzSmcdNo6QsM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8N490-2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769878|ensembl:ENSP00000248451	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:q8n490-2(display_long)|uniprotkb:PNKD(gene name)|psi-mi:PNKD(display_short)|uniprotkb:KIAA1184(gene name synonym)|uniprotkb:MR1(gene name synonym)|uniprotkb:TAHCCP2(gene name synonym)|uniprotkb:Myofibrillogenesis regulator 1(gene name synonym)|uniprotkb:Paroxysmal nonkinesiogenic dyskinesia protein(gene name synonym)|uniprotkb:Trans-activated by hepatitis C virus core protein 2(gene name synonym)|uniprotkb:FKSG19(orf name)|uniprotkb:UNQ2491/PRO5778(orf name)|uniprotkb:MR-1S(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000127838(gene)|ensembl:ENST00000248451(transcript)|intact:EBI-746368(isoform-parent)|uniprotkb:Q8N490-2(isoform-parent)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:cpTDxscb3w5klM/N5tkYzkkJcI89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8N1F7	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pkk5pooUC4yQShpqjiwNLddfy149606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UG63	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2959697|ensembl:ENSP00000287844|uniprotkb:Q96TE8|uniprotkb:O60864|uniprotkb:Q75MJ0|uniprotkb:Q75MJ1	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:abcf2_human(display_long)|uniprotkb:ABCF2(gene name)|psi-mi:ABCF2(display_short)|uniprotkb:Iron-inhibited ABC transporter 2(gene name synonym)|uniprotkb:HUSSY-18(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000033050(gene)|ensembl:ENST00000287844(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|mint:Q9UG63|go:"GO:0016020"(membrane)|refseq:NP_005683.2|refseq:NP_009120.1|refseq:XP_016867128.1|refseq:XP_016867129.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:TdGWfZ4OYohgxKLL1uyz7X+FWmQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q6P1M0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P11441	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356983|uniprotkb:Q5HY80|ensembl:ENSP00000358674	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ubl4a_human(display_long)|uniprotkb:UBL4A(gene name)|psi-mi:UBL4A(display_short)|uniprotkb:GDX(gene name synonym)|uniprotkb:DXS254E(gene name synonym)|uniprotkb:UBL4(gene name synonym)|uniprotkb:Ubiquitin-like protein GDX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_055050.1|ensembl:ENSG00000102178(gene)|ensembl:ENST00000369660(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016020"(membrane)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR041421|interpro:IPR044724|mint:P11441|rcsb pdb:2DZI|rcsb pdb:4WWR|rcsb pdb:4X86|reactome:R-HSA-9609523	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:euKOrDRC1mx0s2QVY95010PRaIg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q53H12	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2269837|uniprotkb:Q75KN1|uniprotkb:Q96GC3|uniprotkb:Q9NP48|ensembl:ENSP00000496789|ensembl:ENSP00000497280|ensembl:ENSP00000498112|ensembl:ENSP00000458417	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:agk_human(display_long)|uniprotkb:AGK(gene name)|psi-mi:AGK(display_short)|uniprotkb:MULK(gene name synonym)|uniprotkb:Multiple substrate lipid kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:XP_011514699.1|refseq:NP_060708.1|ensembl:ENSG00000006530(gene)|ensembl:ENST00000575872(transcript)|ensembl:ENST00000648068(transcript)|ensembl:ENST00000649286(transcript)|ensembl:ENST00000650547(transcript)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0001729"(ceramide kinase activity)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042721"(TIM22 mitochondrial import inner membrane insertion complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046486"(glycerolipid metabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0047620"(acylglycerol kinase activity)|go:"GO:0102773"(dihydroceramide kinase activity)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|go:"GO:0005743"(mitochondrial inner membrane)|ensembl:ENSG00000262327(gene)|rcsb pdb:7CGP|reactome:R-HSA-1483206|reactome:R-HSA-6802952|mint:Q53H12	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:aUz/aYnkviiUE/ijNEddfOQmjZQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q53GQ0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2963255|uniprotkb:Q96EA9|ensembl:ENSP00000278353|uniprotkb:A8K9B0|uniprotkb:Q9Y6G8|uniprotkb:Q96JU2|uniprotkb:D3DR23	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dhb12_human(display_long)|uniprotkb:HSD17B12(gene name)|psi-mi:HSD17B12(display_short)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:SDR12C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 1(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000149084(gene)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0009923"(fatty acid elongase complex)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0050062"(long-chain-fatty-acyl-CoA reductase activity)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|ensembl:ENST00000278353(transcript)|go:"GO:0102339"(3-oxo-arachidoyl-CoA reductase activity)|go:"GO:0102341"(3-oxo-lignoceroyl-CoA reductase activity)|go:"GO:0102342"(3-oxo-cerotoyl-CoA reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q53GQ0|reactome:R-HSA-193048|reactome:R-HSA-75876|go:"GO:0102340"(3-oxo-behenoyl-CoA reductase activity)|refseq:NP_057226.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:2R2pFY0c9yRuCvLU2J8n2urR+0o9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q16891	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15369	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15365	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15181	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-712298|ensembl:ENSP00000362329|uniprotkb:Q2M348|uniprotkb:Q5SQT7|uniprotkb:Q6P7P4|uniprotkb:Q9UQJ5|uniprotkb:Q9Y5B1	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ipyr_human(display_long)|uniprotkb:Pyrophosphate phospho-hydrolase(gene name synonym)|uniprotkb:PPA1(gene name)|psi-mi:PPA1(display_short)|uniprotkb:IOPPP(gene name synonym)|uniprotkb:PP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000180817(gene)|ensembl:ENST00000373232(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q15181|rcsb pdb:6C45|rcsb pdb:7BTN|rcsb pdb:7CMO|reactome:R-HSA-379716|reactome:R-HSA-71737|refseq:NP_066952.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1094gn9aeisgfDUhIroRn2iqom49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15046	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356367|uniprotkb:A8MSK1|uniprotkb:Q9HB23|uniprotkb:O14946|uniprotkb:Q96J25|ensembl:ENSP00000303043|uniprotkb:D3DUK4	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:syk_human(display_long)|uniprotkb:KARS1(gene name)|psi-mi:KARS1(display_short)|uniprotkb:KARS(gene name synonym)|uniprotkb:KIAA0070(gene name synonym)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001123561.1|refseq:NP_005539.1|go:"GO:0016597"(amino acid binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0005739"(mitochondrion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018149|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR034762|interpro:IPR044136|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:Q15046|go:"GO:0006430"(lysyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|rcsb pdb:3BJU|rcsb pdb:4DPG|go:"GO:0010165"(response to X-ray)|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:6CHD|rcsb pdb:6ILD|rcsb pdb:6ILH|rcsb pdb:7EA9|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|ensembl:ENSG00000065427(gene)|ensembl:ENST00000302445(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0003877"(ATP adenylyltransferase activity)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|dip:DIP-29725N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:YLjIdoUW7DiNp+Pj1OPg8jhnC5w9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q14978	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-396155|uniprotkb:Q15030|intact:EBI-1055664|uniprotkb:Q9BUV3|uniprotkb:Q5VV70|ensembl:ENSP00000474710	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:nolc1_human(display_long)|uniprotkb:NOLC1(gene name)|psi-mi:NOLC1(display_short)|uniprotkb:KIAA0035(gene name synonym)|uniprotkb:Nucleolar 130 kDa protein(gene name synonym)|uniprotkb:140 kDa nucleolar phosphoprotein(gene name synonym)|uniprotkb:Nucleolar phosphoprotein p130(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 13(gene name synonym)|uniprotkb:NS5ATP13(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004732.2|refseq:NP_001271317.1|refseq:NP_001271318.1|ensembl:ENSG00000166197(gene)|ensembl:ENST00000605788(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001093"(TFIIB-class transcription factor binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007000"(nucleolus organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0015030"(Cajal body)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0033979"(box H/ACA RNA metabolic process)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0042306"(regulation of protein import into nucleus)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0062064"(box C/D snoRNP complex binding)|go:"GO:0062065"(box H/ACA snoRNP complex binding)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR007718(SRP40, C-terminal)|mint:Q14978	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:G3ClYMfSSjWsDzkxtahX5lLRzzQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q14657	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052105|uniprotkb:Q5HY39|uniprotkb:Q8IZ78|ensembl:ENSP00000349923	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:lage3_human(display_long)|uniprotkb:Protein ITBA2(gene name synonym)|uniprotkb:Protein ESO-3(gene name synonym)|uniprotkb:ITBA2(gene name synonym)|uniprotkb:LAGE3(gene name)|psi-mi:LAGE3(display_short)|uniprotkb:DXS9879E(gene name synonym)|uniprotkb:ESO3(gene name synonym)|uniprotkb:L antigen family member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006005.2|ensembl:ENSG00000196976(gene)|ensembl:ENST00000357360(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008033"(tRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070525"(tRNA threonylcarbamoyladenosine metabolic process)|interpro:IPR015419(Transcription factor Pcc1)|rcsb pdb:6GWJ|reactome:R-HSA-6782315	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:i85i7GnA4k4+zsftYKYMk+xWAFM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q13526	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-714158|uniprotkb:Q53X75|ensembl:ENSP00000247970|ensembl:ENSP00000466962|uniprotkb:A8K4V9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pin1_human(display_long)|uniprotkb:Rotamase Pin1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)|uniprotkb:PIN1(gene name)|psi-mi:PIN1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000127445(gene)|ensembl:ENST00000247970(transcript)|ensembl:ENST00000588695(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0016859"(cis-trans isomerase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050808"(synapse organization)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060393"(regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:2000146"(negative regulation of cell motility)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR023058|interpro:IPR036020|mint:Q13526|rcsb pdb:1F8A|rcsb pdb:1I6C|rcsb pdb:1I8G|rcsb pdb:1I8H|rcsb pdb:1NMV|rcsb pdb:1NMW|rcsb pdb:1PIN|rcsb pdb:1ZCN|rcsb pdb:2F21|rcsb pdb:2ITK|rcsb pdb:2KBU|rcsb pdb:2KCF|rcsb pdb:2LB3|rcsb pdb:2M8I|rcsb pdb:2M8J|rcsb pdb:2M9E|rcsb pdb:2M9F|rcsb pdb:2M9I|rcsb pdb:2M9J|rcsb pdb:2N1O|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJA|rcsb pdb:7NRK|rcsb pdb:7NRL|reactome:R-HSA-1169408|reactome:R-HSA-5668599|reactome:R-HSA-6804756|reactome:R-HSA-6811555|reactome:R-HSA-936440|rcsb pdb:2RUC|rcsb pdb:2RUD|rcsb pdb:2RUQ|rcsb pdb:2RUR|rcsb pdb:2XP3|rcsb pdb:2XP4|rcsb pdb:2XP5|rcsb pdb:2XP6|rcsb pdb:2XP7|rcsb pdb:2XP8|rcsb pdb:2XP9|rcsb pdb:2XPA|rcsb pdb:2XPB|rcsb pdb:2ZQS|rcsb pdb:2ZQT|rcsb pdb:2ZQU|rcsb pdb:2ZQV|rcsb pdb:2ZR4|rcsb pdb:2Q5A|rcsb pdb:2ZR5|rcsb pdb:2ZR6|rcsb pdb:3I6C|rcsb pdb:4TYO|rcsb pdb:4U84|rcsb pdb:4U85|rcsb pdb:4U86|rcsb pdb:5B3W|rcsb pdb:5B3X|rcsb pdb:5B3Y|rcsb pdb:5B3Z|rcsb pdb:5BMY|rcsb pdb:5GPH|rcsb pdb:5UY9|rcsb pdb:5VTI|rcsb pdb:5VTJ|rcsb pdb:5VTK|rcsb pdb:6DUN|rcsb pdb:6O33|rcsb pdb:6O34|rcsb pdb:6SVC|rcsb pdb:6SVE|rcsb pdb:6SVH|rcsb pdb:6VAJ|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:4TNS|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:3IKD|rcsb pdb:3IKG|rcsb pdb:3JYJ|rcsb pdb:3KAB|rcsb pdb:3KAC|rcsb pdb:3KAD|rcsb pdb:3KAF|rcsb pdb:3KAG|rcsb pdb:3KAH|rcsb pdb:3KAI|rcsb pdb:3KCE|rcsb pdb:3NTP|rcsb pdb:3ODK|rcsb pdb:3OOB|rcsb pdb:3TC5|rcsb pdb:3TCZ|rcsb pdb:3TDB|rcsb pdb:3WH0|rcsb pdb:4GWT|rcsb pdb:4GWV|rcsb pdb:3IK8|rcsb pdb:4QIB|refseq:NP_006212.1|dip:DIP-29306N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:FICkSpcBgvSDFW4iY1Etik85xNo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q13155	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q13148	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q06830	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q05682	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q02978	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|ensembl:ENSP00000225665|uniprotkb:F5GY65	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003553.2|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|mint:Q02978|reactome:R-HSA-70263|ensembl:ENSG00000108528(gene)|ensembl:ENST00000225665(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015367"("oxoglutarate:malate antiporter activity")|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q00325	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325	-	-	crc64:78714C85931B22D5	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P68036	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P62837	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P61088	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P61077	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P60604	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P60468	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P58546	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051736|ensembl:ENSP00000376800	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mtpn_human(display_long)|uniprotkb:Protein V-1(gene name synonym)|uniprotkb:MTPN(gene name)|psi-mi:MTPN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_665807.1|ensembl:ENSG00000105887(gene)|ensembl:ENST00000393085(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010557"(positive regulation of macromolecule biosynthetic process)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000812"(regulation of barbed-end actin filament capping)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P58546|rcsb pdb:3AAA|rcsb pdb:7DF7|rcsb pdb:7DSA|rcsb pdb:7DSB|dip:DIP-50234N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:kdJ8vNN4yI2ye49iYUNAtH538b49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P55060	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P53985	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|uniprotkb:Q49A45|ensembl:ENSP00000416167|ensembl:ENSP00000441065|ensembl:ENSP00000485688|ensembl:ENSP00000358640|ensembl:ENSP00000397106|ensembl:ENSP00000399104|ensembl:ENSP00000486000|ensembl:ENSP00000505879	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|ensembl:ENSG00000155380(gene)|ensembl:ENSG00000281917(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032094"(response to food)|ensembl:ENST00000369626(transcript)|ensembl:ENST00000429288(transcript)|ensembl:ENST00000443580(transcript)|ensembl:ENST00000458229(transcript)|ensembl:ENST00000538576(transcript)|ensembl:ENST00000628110(transcript)|ensembl:ENST00000630362(transcript)|ensembl:ENST00000679803(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015130"(mevalonate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0015728"(mevalonate transport)|go:"GO:0016020"(membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051780"(behavioral response to nutrient)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030757|interpro:IPR036259|mint:P53985|go:"GO:1905039"(carboxylic acid transmembrane transport)|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P53007	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005975.1|ensembl:ENSG00000100075(gene)|ensembl:ENST00000215882(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006843"(mitochondrial citrate transmembrane transport)|go:"GO:0015137"(citrate transmembrane transporter activity)|go:"GO:0015142"(tricarboxylic acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071913"(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:P53007|reactome:R-HSA-70263|reactome:R-HSA-75105	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51965	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51668	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51571	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P49458	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-350743|uniprotkb:Q6NVX0|uniprotkb:Q8WTW0|ensembl:ENSP00000305230|uniprotkb:A8K0N0	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:srp09_human(display_long)|uniprotkb:SRP9(gene name)|psi-mi:SRP9(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	rcsb pdb:4UYJ|refseq:NP_001123912.1|refseq:NP_003124.1|ensembl:ENSG00000143742(gene)|ensembl:ENST00000304786(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|mint:P49458|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-6151N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Y33fEeeXnma9oF7Fzs6zEGQjVBU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P48507	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051387|uniprotkb:Q6FHC1|uniprotkb:Q9NPX9|uniprotkb:Q9NU74|uniprotkb:A8K334|uniprotkb:M5A959|uniprotkb:D3DT45|ensembl:ENSP00000359258	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:gsh0_human(display_long)|uniprotkb:Gamma-glutamylcysteine synthetase regulatory subunit(gene name synonym)|uniprotkb:Gamma-ECS regulatory subunit(gene name synonym)|uniprotkb:GCS light chain(gene name synonym)|uniprotkb:Glutamate--cysteine ligase modifier subunit(gene name synonym)|uniprotkb:GCLM(gene name)|psi-mi:GCLM(display_short)|uniprotkb:GLCLR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002052.1|refseq:NP_001295182.1|ensembl:ENSG00000023909(gene)|ensembl:ENST00000370238(transcript)|go:"GO:0004357"(glutamate-cysteine ligase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006534"(cysteine metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0014823"(response to activity)|go:"GO:0017109"(glutamate-cysteine ligase complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035226"(glutamate-cysteine ligase catalytic subunit binding)|go:"GO:0035229"(positive regulation of glutamate-cysteine ligase activity)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0042493"|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0097069"(cellular response to thyroxine stimulus)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR023210|interpro:IPR032963|interpro:IPR036812|reactome:R-HSA-174403|reactome:R-HSA-5578999	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:arU12Xm86K7yRxElliA31V7z5d89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P46379	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P46109	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P43487	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1032909|uniprotkb:Q53EY3|ensembl:ENSP00000327583	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rang_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002873.1|ensembl:ENSG00000099901(gene)|ensembl:ENST00000331821(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1K5D|rcsb pdb:1K5G|reactome:R-HSA-165054|refseq:NP_001265568.1|refseq:NP_001265569.1|dip:DIP-35058N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:OWndphaUCDSO3+MGhJqcuQo2Lk09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P43246	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P40222	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359793|uniprotkb:Q5TFJ6|uniprotkb:Q66K62|uniprotkb:Q86T54|uniprotkb:Q86T85|uniprotkb:Q86T86|uniprotkb:Q86Y86|uniprotkb:Q86YW3|uniprotkb:Q8N2Y3|uniprotkb:D3DPP6|ensembl:ENSP00000362711|ensembl:ENSP00000362712	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:txlna_human(display_long)|uniprotkb:TXLNA(gene name)|psi-mi:TXLNA(display_short)|uniprotkb:TXLN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_787048.1|ensembl:ENSG00000084652(gene)|ensembl:ENST00000373609(transcript)|ensembl:ENST00000373610(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0042113"(B cell activation)|interpro:IPR026183|reactome:R-HSA-449836|refseq:XP_016856051.1|dip:DIP-27612N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:m6McBNTQ5VY4RNUY6PyYTj97YUk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P38646	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P36969	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2510844|uniprotkb:O43381|uniprotkb:Q9UPK2|uniprotkb:Q6PJ59|ensembl:ENSP00000346103	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:gpx4_human(display_long)|uniprotkb:GPX4(gene name)|psi-mi:GPX4(display_short)|uniprotkb:Glutathione peroxidase 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002076.2|refseq:NP_001034936.1|dip:DIP-53543N|reactome:R-HSA-9023661|reactome:R-HSA-9020265|ensembl:ENSG00000167468(gene)|ensembl:ENST00000354171(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008430"(selenium binding)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051258"(protein polymerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0110076"(negative regulation of ferroptosis)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|rcsb pdb:2GS3|rcsb pdb:2OBI|rcsb pdb:5H5Q|rcsb pdb:5H5R|rcsb pdb:5H5S|rcsb pdb:6ELW|rcsb pdb:6HKQ|rcsb pdb:6HN3|reactome:R-HSA-2142688|reactome:R-HSA-2142712|reactome:R-HSA-2142770|reactome:R-HSA-9018676|reactome:R-HSA-9018896	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:SUjUUl4rV/SKmLkV6WOiM+nusio9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P36542	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-711768|uniprotkb:Q5VYP3|uniprotkb:Q96AS8|uniprotkb:A8KA31|intact:EBI-3962282|uniprotkb:Q6I9V2|ensembl:ENSP00000349142	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:atpg_human(display_long)|uniprotkb:ATP5F1C(gene name)|psi-mi:ATP5F1C(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:ATP5C(gene name synonym)|uniprotkb:ATP5C1(gene name synonym)|uniprotkb:ATP5CL1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001001973.1|refseq:NP_005165.1|ensembl:ENSG00000165629(gene)|ensembl:ENST00000356708(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|interpro:IPR035968|mint:P36542|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:k3Nfa1hSoREyiKzFbmaZqxLhiLY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P35613	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P35520	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P34932	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P32119	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P31689	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P31040	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P30044	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-722161|uniprotkb:Q14CK0|uniprotkb:Q6IAF2|uniprotkb:Q9UBU5|uniprotkb:Q9UJU4|uniprotkb:Q9UKX4|uniprotkb:A6NG06|uniprotkb:B7ZLJ4|uniprotkb:A6NC19|uniprotkb:B7ZVW3|ensembl:ENSP00000265462	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prdx5_human(display_long)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:TPx type VI(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 71B(gene name synonym)|uniprotkb:Alu corepressor 1(gene name synonym)|uniprotkb:PRDX5(gene name)|psi-mi:PRDX5(display_short)|uniprotkb:ACR1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)|uniprotkb:SBBI10(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_036226.1|refseq:NP_857634.1|refseq:NP_857635.1|ensembl:ENSG00000126432(gene)|ensembl:ENST00000265462(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037944|mint:P30044|rcsb pdb:1H4O|rcsb pdb:1HD2|rcsb pdb:1OC3|rcsb pdb:1URM|rcsb pdb:2VL2|rcsb pdb:2VL3|rcsb pdb:2VL9|rcsb pdb:3MNG|rcsb pdb:4K7I|rcsb pdb:4K7N|rcsb pdb:4K7O|rcsb pdb:4MMM|reactome:R-HSA-3299685|reactome:R-HSA-5628897	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Z1fs04RUXWI7z+s7Y+hzGige4mU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P30040	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-946830|uniprotkb:Q3MJC3|uniprotkb:Q6FHT4|uniprotkb:C9J183|ensembl:ENSP00000261735	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:erp29_human(display_long)|uniprotkb:ERP29(gene name)|psi-mi:ERP29(display_short)|uniprotkb:C12orf8(gene name synonym)|uniprotkb:ERP28(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 31(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006808.1|refseq:NP_001029197.1|ensembl:ENSG00000089248(gene)|ensembl:ENST00000261735(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043335"(protein unfolding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR011679(Endoplasmic reticulum, protein ERp29, C-terminal)|interpro:IPR012883(ERp29, N-terminal)|interpro:IPR016855(Endoplasmic reticulum, protein ERp29)|interpro:IPR036249|interpro:IPR036356|rcsb pdb:2QC7|rcsb pdb:5V8Z|rcsb pdb:5V90	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5+uNyIlUU6txfPlS4DSPunpjz3M9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P29372	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1043398|uniprotkb:Q13770|uniprotkb:Q15275|uniprotkb:Q15961|uniprotkb:Q96BZ6|uniprotkb:Q96S33|uniprotkb:Q9NNX5|ensembl:ENSP00000219431|intact:EBI-10970139|uniprotkb:G5E9E2|uniprotkb:Q5J9I4	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:3mg_human(display_long)|uniprotkb:3-methyladenine DNA glycosidase(gene name synonym)|uniprotkb:ADPG(gene name synonym)|uniprotkb:3-alkyladenine DNA glycosylase(gene name synonym)|uniprotkb:N-methylpurine-DNA glycosylase(gene name synonym)|uniprotkb:MPG(gene name)|psi-mi:MPG(display_short)|uniprotkb:AAG(gene name synonym)|uniprotkb:ANPG(gene name synonym)|uniprotkb:MID1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000103152(gene)|ensembl:ENST00000219431(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003905"(alkylbase DNA N-glycosylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008725"(DNA-3-methyladenine glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043916"(DNA-7-methylguanine glycosylase activity)|go:"GO:0045007"(depurination)|go:"GO:0052821"(DNA-7-methyladenine glycosylase activity)|go:"GO:0052822"(DNA-3-methylguanine glycosylase activity)|interpro:IPR003180("Methylpurine-DNA glycosylase (MPG)")|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR036995|mint:P29372|rcsb pdb:1BNK|rcsb pdb:1EWN|rcsb pdb:1F4R|rcsb pdb:1F6O|rcsb pdb:3QI5|rcsb pdb:3UBY|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-110357|refseq:NP_001015052.1|refseq:NP_002425.2|refseq:NP_001015054.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:DIssmhwGHsxiJoewCmV2zDEmSuI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P28482	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:odzhd70I/8uWedx0+gF38lhe60I9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P27708	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P23921	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P23193	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2608271|uniprotkb:A6NF25|uniprotkb:A8K339|uniprotkb:Q15563|uniprotkb:Q6FG87|ensembl:ENSP00000428426	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tcea1_human(display_long)|uniprotkb:TCEA1(gene name)|psi-mi:TCEA1(display_short)|uniprotkb:GTF2S(gene name synonym)|uniprotkb:TFIIS(gene name synonym)|uniprotkb:Transcription elongation factor S-II protein 1(gene name synonym)|uniprotkb:Transcription elongation factor TFIIS.o(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006747.1|refseq:NP_958845.1|ensembl:ENSG00000187735(gene)|ensembl:ENST00000521604(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901919"(positive regulation of exoribonuclease activity)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR006289(Transcription elongation factor, TFIIS)|interpro:IPR017923|interpro:IPR035100|interpro:IPR035441|interpro:IPR036575|mint:P23193|reactome:R-HSA-167243|reactome:R-HSA-167246|rcsb pdb:1TFI|reactome:R-HSA-167287|rcsb pdb:3NDQ|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:6O9L|reactome:R-HSA-112382|reactome:R-HSA-167290|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-48480N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:88QvzePEd32tHYxrij2EoOYkaLk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P21912	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1056481|uniprotkb:Q9NQ12|uniprotkb:Q0QEY7|uniprotkb:B2R545|ensembl:ENSP00000364649	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sdhb_human(display_long)|uniprotkb:SDHB(gene name)|psi-mi:SDHB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002991.2|ensembl:ENSG00000117118(gene)|ensembl:ENST00000375499(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-39666N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7xnswe3IVEFJiXqGhxF0Az3EmvE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P17812	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042983|uniprotkb:Q5VW67|uniprotkb:Q96GK6|ensembl:ENSP00000361699|ensembl:ENSP00000497602|ensembl:ENSP00000497744|uniprotkb:D3DPW1|uniprotkb:B4DR64	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pyrg1_human(display_long)|uniprotkb:CTPS1(gene name)|psi-mi:CTPS1(display_short)|uniprotkb:CTP synthetase 1(gene name synonym)|uniprotkb:CTPS(gene name synonym)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000171793(gene)|ensembl:ENST00000372616(transcript)|ensembl:ENST00000649124(transcript)|ensembl:ENST00000650070(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|mint:P17812|rcsb pdb:2VO1|rcsb pdb:5U03|reactome:R-HSA-499943|refseq:NP_001288166.1|refseq:NP_001896.2	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:0QkxA3YRejXU0X7dk7zf1XeAMt89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P17066	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P16152	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-351348|uniprotkb:Q3LHW8|uniprotkb:B2RBZ7|ensembl:ENSP00000290349|uniprotkb:B4DFK7	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cbr1_human(display_long)|uniprotkb:SDR21C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 21C member 1(gene name synonym)|uniprotkb:CBR1(gene name)|psi-mi:CBR1(display_short)|uniprotkb:CBR(gene name synonym)|uniprotkb:CRN(gene name synonym)|uniprotkb:NADPH-dependent carbonyl reductase 1(gene name synonym)|uniprotkb:"Prostaglandin-E(2) 9-reductase"(gene name synonym)|uniprotkb:Prostaglandin 9-ketoreductase(gene name synonym)|uniprotkb:"15-hydroxyprostaglandin dehydrogenase [NADP(+)]"(gene name synonym)|uniprotkb:20-beta-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001748.1|ensembl:ENSG00000159228(gene)|ensembl:ENST00000290349(transcript)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005829"(cytosol)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0017144"|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042373"(vitamin K metabolic process)|go:"GO:0047020"("15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity")|go:"GO:0047021"("15-hydroxyprostaglandin dehydrogenase (NADP+) activity")|go:"GO:0050221"(prostaglandin-E2 9-reductase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P16152|rcsb pdb:1WMA|rcsb pdb:2PFG|rcsb pdb:3BHI|rcsb pdb:3BHJ|rcsb pdb:3BHM|rcsb pdb:4Z3D|reactome:R-HSA-2162123|refseq:NP_001273718.1|dip:DIP-33136N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:ROzNiYne9nXfvDC9Hi3Ni6M7ILA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P11142	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P11021	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P10599	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|uniprotkb:Q9UDG5|intact:EBI-1042712|ensembl:ENSP00000363641	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|ensembl:ENSG00000136810(gene)|ensembl:ENST00000374517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:1W1C|rcsb pdb:1W1E|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P08243	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-722989|uniprotkb:P08184|uniprotkb:Q15666|uniprotkb:Q549T9|uniprotkb:Q96HD0|ensembl:ENSP00000175506|ensembl:ENSP00000377845|ensembl:ENSP00000377846|uniprotkb:A4D1I8|uniprotkb:D6W5R3|uniprotkb:B4DXZ1|uniprotkb:B7ZAA9|uniprotkb:E9PCI3|uniprotkb:E9PCX6	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:asns_human(display_long)|uniprotkb:Glutamine-dependent asparagine synthetase(gene name synonym)|uniprotkb:Cell cycle control protein TS11(gene name synonym)|uniprotkb:ASNS(gene name)|psi-mi:ASNS(display_short)|uniprotkb:TS11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001171546.1|refseq:NP_001171547.1|refseq:NP_001171548.1|refseq:NP_001664.3|refseq:NP_597680.2|refseq:NP_899199.2|ensembl:ENSG00000070669(gene)|ensembl:ENST00000175506(transcript)|ensembl:ENST00000394308(transcript)|ensembl:ENST00000394309(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0031427"(response to methotrexate)|go:"GO:0032354"(response to follicle-stimulating hormone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|rcsb pdb:6GQ3|reactome:R-HSA-380994|reactome:R-HSA-8963693|reactome:R-HSA-9633012|reactome:R-HSA-9648895	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:McR8Ve0DzWhe3JWMYLsCRChiBaY9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P08195	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P08107	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P07919	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1224427|uniprotkb:Q5TDF6|uniprotkb:Q6LDB8|uniprotkb:Q9BQ91|uniprotkb:D3DQ18|uniprotkb:B2R4V9|ensembl:ENSP00000309565	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:qcr6_human(display_long)|uniprotkb:UQCRH(gene name)|psi-mi:UQCRH(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase complex 11 kDa protein(gene name synonym)|uniprotkb:Cytochrome c1 non-heme 11 kDa protein(gene name synonym)|uniprotkb:Mitochondrial hinge protein(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Complex III subunit 6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005995.2|ensembl:ENSG00000173660(gene)|ensembl:ENST00000311672(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|interpro:IPR003422(Ubiquinol-cytochrome C reductase hinge)|interpro:IPR023184|interpro:IPR036811|mint:P07919|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1f1RPTV/dS3CK24n/YSvDPXLm5c9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P05141	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P02452	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-982999|uniprotkb:O76045|uniprotkb:P78441|uniprotkb:Q13896|uniprotkb:Q13902|uniprotkb:Q13903|uniprotkb:Q14037|uniprotkb:Q14992|uniprotkb:Q15176|uniprotkb:Q15201|uniprotkb:Q16050|uniprotkb:Q59F64|uniprotkb:Q7KZ30|uniprotkb:Q7KZ34|uniprotkb:Q8IVI5|ensembl:ENSP00000225964|uniprotkb:Q8N473|uniprotkb:Q9UML6|uniprotkb:Q9UMM7	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:co1a1_human(display_long)|uniprotkb:Alpha-1 type I collagen(gene name synonym)|uniprotkb:COL1A1(gene name)|psi-mi:COL1A1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000079.2|ensembl:ENSG00000108821(gene)|ensembl:ENST00000225964(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002020"(protease binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005584"(collagen type I trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030141"(secretory granule)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032355"(response to estradiol)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034505"(tooth mineralization)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043588"(skin development)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044691"(tooth eruption)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0051591"(response to cAMP)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902618"(cellular response to fluoride)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|mint:P02452|rcsb pdb:1Q7D|rcsb pdb:2LLP|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:5CVB|rcsb pdb:5K31|rcsb pdb:5OU8|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|rcsb pdb:5OU9|rcsb pdb:7E7B|rcsb pdb:7E7D|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8940973|reactome:R-HSA-8948216|dip:DIP-36077N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:x83+B64Cl9zkAVeZ9RCo0BukkwU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95831	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95816	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95551	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95399	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769832|uniprotkb:Q5H8X7|uniprotkb:Q6UXF6|uniprotkb:Q9UKP7|ensembl:ENSP00000355163	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:uts2_human(display_long)|uniprotkb:UNQ525/PRO1068(orf name)|uniprotkb:Urotensin II(gene name synonym)|uniprotkb:UTS2(gene name)|psi-mi:UTS2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006777.1|refseq:NP_068835.1|refseq:XP_011538839.1|refseq:XP_011538840.1|ensembl:ENST00000361696(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006936"(muscle contraction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0045202"(synapse)|go:"GO:0097746"(blood vessel diameter maintenance)|interpro:IPR001483(Urotensin II)|rcsb pdb:6HVB|rcsb pdb:6HVC|reactome:R-HSA-375276|reactome:R-HSA-416476|ensembl:ENSG00000049247(gene)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:EGHV5udqqQh8aJlsg4We0FR6XIs9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95163	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347559|uniprotkb:Q9H327|uniprotkb:Q9UG87|uniprotkb:Q5JSV2|ensembl:ENSP00000363779|ensembl:ENSP00000501893	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:elp1_human(display_long)|uniprotkb:ELP1(gene name)|psi-mi:ELP1(display_short)|uniprotkb:IKAP(gene name synonym)|uniprotkb:IKBKAP(gene name synonym)|uniprotkb:p150(gene name synonym)|uniprotkb:IkappaB kinase complex-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	dip:DIP-27579N|refseq:NP_003631.2|refseq:NP_001305289.1|ensembl:ENSG00000070061(gene)|ensembl:ENST00000374647(transcript)|ensembl:ENST00000675406(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR006849(IKI3)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O95163|rcsb pdb:5CQR|reactome:R-HSA-3214847|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hl+inV6TcN+DGu9CwE3SitkHiI09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O60716	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:HgMvbcDKedE291TIvIOqLFT3srw9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O43837	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-725377|uniprotkb:O95106|uniprotkb:Q5JXS8|uniprotkb:Q9NQ06|uniprotkb:Q9NQ07|uniprotkb:Q9UEX0|uniprotkb:Q9UG99|uniprotkb:B2RDR1|uniprotkb:D3DVX2|uniprotkb:D3DVX3|uniprotkb:Q9NUZ0|ensembl:ENSP00000370223	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:idh3b_human(display_long)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_008830.2|refseq:NP_777280.1|ensembl:ENSG00000101365(gene)|ensembl:ENST00000380843(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:O43837|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:7CE3|reactome:R-HSA-71403|refseq:NP_001317692.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:in3sFQUqN4ZtqBii7BotVro104A9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O43681	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2515857|ensembl:ENSP00000349887|ensembl:ENSP00000466379|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000198356(gene)|ensembl:ENST00000357332(transcript)|ensembl:ENST00000591090(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|reactome:R-HSA-9609523|refseq:NP_004308.2	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O43175	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O15067	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052653|uniprotkb:A6H8V8|ensembl:ENSP00000313490	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pur4_human(display_long)|uniprotkb:Formylglycinamide ribotide amidotransferase(gene name synonym)|uniprotkb:PFAS(gene name)|psi-mi:PFAS(display_short)|uniprotkb:KIAA0361(gene name synonym)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_036525.1|ensembl:ENSG00000178921(gene)|ensembl:ENST00000314666(transcript)|go:"GO:0004642"(phosphoribosylformylglycinamidine synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097065"(anterior head development)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR029062|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR040707|interpro:IPR041609|mint:O15067|reactome:R-HSA-73817	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:e52AyHjHUrLjnoJP+rInkcvfGJk9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O14654	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356594|ensembl:ENSP00000505547	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:irs4_human(display_long)|uniprotkb:IRS4(gene name)|psi-mi:IRS4(display_short)|uniprotkb:160 kDa phosphotyrosine protein(gene name synonym)|uniprotkb:Phosphoprotein of 160 kDa(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSP00000505547|refseq:NP_003595.1|ensembl:ENSG00000133124(gene)|ensembl:ENST00000564206(transcript)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039011|reactome:R-HSA-2428928	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:iKGsWaKu2XsU4OGaxhDG8wjcmVc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O00483	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O00264	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O75094	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2622593|uniprotkb:O95804|uniprotkb:Q9UFH5|uniprotkb:A6H8U9|ensembl:ENSP00000430333|uniprotkb:J3KNP3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:slit3_human(display_long)|uniprotkb:KIAA0814(gene name synonym)|uniprotkb:MEGF5(gene name synonym)|uniprotkb:SLIL2(gene name synonym)|uniprotkb:Multiple epidermal growth factor-like domains protein 5(gene name synonym)|uniprotkb:UNQ691/PRO1336(orf name)|uniprotkb:SLIT3(gene name)|psi-mi:SLIT3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003053.1|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428542|ensembl:ENSG00000184347(gene)|ensembl:ENST00000519560(transcript)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051414"(response to cortisol)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|refseq:NP_001258875.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Qazwnc23w/tZ8NsF8G3ZLSEF1SE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96CP2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-9394506|ensembl:ENSP00000293981|ensembl:ENSP00000380159	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fwch2_human(display_long)|uniprotkb:FLYWCH2(gene name)|psi-mi:FLYWCH2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001135971.1|refseq:NP_001135972.1|refseq:NP_612448.1|refseq:XP_005255135.1|ensembl:ENSG00000162076(gene)|ensembl:ENST00000293981(transcript)|ensembl:ENST00000396958(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR029279|interpro:IPR040312	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hFUp5nK4z8ENLRQK2GSYIqTFljg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q2KHR2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1222187|uniprotkb:Q6ZRR1|uniprotkb:Q6ZTY6|uniprotkb:Q8N3J0|uniprotkb:Q9H7A9|uniprotkb:Q9H956|ensembl:ENSP00000501248|ensembl:ENSP00000501278	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rfx7_human(display_long)|uniprotkb:RFXDC2(gene name synonym)|uniprotkb:Regulatory factor X 7(gene name synonym)|uniprotkb:Regulatory factor X domain-containing protein 2(gene name synonym)|uniprotkb:RFX7(gene name)|psi-mi:RFX7(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_073752.5|refseq:XP_011520227.1|refseq:XP_016877996.1|refseq:XP_016877997.1|ensembl:ENSG00000181827(gene)|ensembl:ENST00000673997(transcript)|ensembl:ENST00000674082(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|rcsb pdb:4QQI|rcsb pdb:6MEW	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:rs7zpZEFUplmE+r8TgFcmQ9LYrU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P35080	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-473138|uniprotkb:Q8WVF9|uniprotkb:Q9HBK2|uniprotkb:B2R4C8|uniprotkb:Q4VBQ4|uniprotkb:D3DNI4|ensembl:ENSP00000239940	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prof2_human(display_long)|uniprotkb:PFN2(gene name)|psi-mi:PFN2(display_short)|uniprotkb:Profilin II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002619.1|refseq:NP_444252.1|ensembl:ENSG00000070087(gene)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010633"(negative regulation of epithelial cell migration)|ensembl:ENST00000239940(transcript)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029891|interpro:IPR036140|mint:P35080|rcsb pdb:1D1J|reactome:R-HSA-376176|reactome:R-HSA-5663220	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:064T9afVEb7WrgJPLVbKByJDUXc9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q16527	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2959737|ensembl:ENSP00000310901|ensembl:ENSP00000450056|uniprotkb:Q93030	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:csrp2_human(display_long)|uniprotkb:CSRP2(gene name)|psi-mi:CSRP2(display_short)|uniprotkb:LMO5(gene name synonym)|uniprotkb:SMLIM(gene name synonym)|uniprotkb:Cysteine-rich protein 2(gene name synonym)|uniprotkb:LIM domain only protein 5(gene name synonym)|uniprotkb:Smooth muscle cell LIM protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001312.1|ensembl:ENSG00000175183(gene)|ensembl:ENST00000311083(transcript)|ensembl:ENST00000546966(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0060537"(muscle tissue development)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001287894.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:nyQ01E4UJb21IE/mZhZjXakJoyo9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y277	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-354196|uniprotkb:Q9UIS0|ensembl:ENSP00000022615	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:vdac3_human(display_long)|uniprotkb:VDAC3(gene name)|psi-mi:VDAC3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001129166.1|refseq:NP_005653.3|ensembl:ENSG00000078668(gene)|ensembl:ENST00000022615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015853"(adenine transport)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030271|mint:Q9Y277|reactome:R-HSA-5689880|reactome:R-HSA-8949215	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:En6g89Dp+C4s1ArGYJyVfUBVsO09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P27816	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-715255|uniprotkb:Q59FT2|uniprotkb:Q68D74|uniprotkb:Q6ZUW9|uniprotkb:Q96NS9|uniprotkb:Q13082|uniprotkb:Q96A76|ensembl:ENSP00000353375|uniprotkb:Q86V26	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:map4_human(display_long)|uniprotkb:MAP4(gene name)|psi-mi:MAP4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001127836.1|refseq:NP_002366.2|ensembl:ENSG00000047849(gene)|ensembl:ENST00000360240(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27816|refseq:NP_112147.2	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:rBf82W3kFCo+2UklK5WHO3MWjV09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P30566	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2511688|ensembl:ENSP00000485525|uniprotkb:B0QY76|uniprotkb:O75495|uniprotkb:Q5TI34	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pur8_human(display_long)|uniprotkb:ADSL(gene name)|psi-mi:ADSL(display_short)|uniprotkb:AMPS(gene name synonym)|uniprotkb:Adenylosuccinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0014850"(response to muscle activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0070626"("(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity")|ensembl:ENSG00000239900(gene)|ensembl:ENST00000623063(transcript)|interpro:IPR000362(Fumarate lyase)|interpro:IPR004769(Adenylosuccinate lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR019468|interpro:IPR020557|interpro:IPR022761|rcsb pdb:2J91|rcsb pdb:2VD6|rcsb pdb:4FFX|rcsb pdb:4FLC|reactome:R-HSA-73817|go:"GO:0001666"(response to hypoxia)|go:"GO:0004018"("N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009060"(aerobic respiration)|refseq:NP_000017.1|refseq:NP_001116850.1|refseq:NP_001304852.1	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:yBhDdHJgZN1NJDpN2ivKLI4oUG09606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51965-2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769826|ensembl:ENSP00000411351	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:p51965-2(display_long)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000170142(gene)|ensembl:ENST00000424381(transcript)|intact:EBI-348546(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:icHkQme/OUwgdkhm+4AwQzwo7Gg9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:B3EWF7	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769821	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ep2a2_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0005634"(nucleus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0032007"(negative regulation of TOR signaling)	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:xXiFLf6cBEd7MKvD9ljDS8cjtUE9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P48444	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1044491|ensembl:ENSP00000264028|uniprotkb:Q52M80|uniprotkb:B4E1X2|uniprotkb:E9PEU4	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:copd_human(display_long)|uniprotkb:Delta-coat protein(gene name synonym)|uniprotkb:ARCN1(gene name)|psi-mi:ARCN1(display_short)|uniprotkb:COPD(gene name synonym)|uniprotkb:Archain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000095139(gene)|ensembl:ENST00000264028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:P48444|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001135753.1|refseq:NP_001646.2|dip:DIP-50375N	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:67dTqyFC/zHDlTapW36OMyXbz0M9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:A1L453	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769805|uniprotkb:Q7RTY6|ensembl:ENSP00000355719	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prs38_human(display_long)|uniprotkb:Marapsin-2(gene name synonym)|uniprotkb:PRSS38(gene name)|psi-mi:PRSS38(display_short)|uniprotkb:MPN2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_898885.1|ensembl:ENSG00000185888(gene)|ensembl:ENST00000366757(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0006508"(proteolysis)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:IQTmn4wcyRhlZomcgyAJ/MZSpuU9606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8TE77-5	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769799	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:q8te77-5(display_long)|uniprotkb:SSH-like protein 3(gene name synonym)|uniprotkb:SSH3(gene name)|psi-mi:SSH3(display_short)|uniprotkb:SSH3L(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	intact:EBI-8743776(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fJ9gnA4S+rVJjF8vNbZzoYosGP49606	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	intact:EBI-10770525	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	-	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:f8vs27_human(display_short)|psi-mi:EBI-10770525(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770028|imex:IM-23897-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	-	-	-	-	figure legend:Table 2,  S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2015/09/23	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	-	-	false	flag tag:n-n	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P27694	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P18754	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-992720|uniprotkb:Q16269|uniprotkb:Q6NT97|ensembl:ENSP00000362939|ensembl:ENSP00000381931|ensembl:ENSP00000508074|ensembl:ENSP00000362938	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rcc1_human(display_long)|uniprotkb:Chromosome condensation protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein(gene name synonym)|uniprotkb:RCC1(gene name)|psi-mi:RCC1(display_short)|uniprotkb:CHC1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001041659.1|refseq:NP_001041660.1|refseq:NP_001041664.1|refseq:NP_001260.1|dip:DIP-35416N|ensembl:ENSG00000180198(gene)|ensembl:ENST00000373832(transcript)|ensembl:ENST00000373833(transcript)|ensembl:ENST00000398958(transcript)|ensembl:ENST00000683442(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016032"(viral process)|rcsb pdb:5E1B|rcsb pdb:5E1D|rcsb pdb:5E1M|rcsb pdb:5E1O|rcsb pdb:5E2A|go:"GO:0031267"(small GTPase binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031492"(nucleosomal DNA binding)|rcsb pdb:5E2B|rcsb pdb:5TBK|rcsb pdb:6DUB|reactome:R-HSA-165054|go:"GO:0031965"(nuclear membrane)|reactome:R-HSA-180746|reactome:R-HSA-9615933|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:P18754|rcsb pdb:1A12|rcsb pdb:1I2M	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:/gP2xQp6fUffHTXpXvs8eb5YJ209606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P14635	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-495332|uniprotkb:A8K066|uniprotkb:Q5TZP9|ensembl:ENSP00000256442	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ccnb1_human(display_long)|uniprotkb:CCNB1(gene name)|psi-mi:CCNB1(display_short)|uniprotkb:CCNB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_114172.1|dip:DIP-59N|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042493"|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046680"(response to DDT)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048565"(digestive tract development)|go:"GO:0051301"(cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060623"(regulation of chromosome condensation)|ensembl:ENSG00000134057(gene)|ensembl:ENST00000256442(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005113"(patched binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0090266"(regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|go:"GO:2000775"(obsolete histone H3-S10 phosphorylation involved in chromosome condensation)|interpro:IPR004367(Cyclin, C-terminal)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071283"("cellular response to iron(III) ion")|interpro:IPR039361|mint:P14635|rcsb pdb:2B9R|rcsb pdb:2JGZ|rcsb pdb:4Y72|rcsb pdb:4YC3|go:"GO:0071398"(cellular response to fatty acid)|rcsb pdb:5HQ0|go:"GO:0071407"(cellular response to organic cyclic compound)|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|reactome:R-HSA-113507|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174048|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|go:"GO:0071456"(cellular response to hypoxia)|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-4419969|reactome:R-HSA-6804114|reactome:R-HSA-68875|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8878166|reactome:R-HSA-8852276	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:WCQWqI2kWZfatq4L2DC0hm26Ix09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O14545	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1396921|uniprotkb:B4DI89|uniprotkb:A8K5L6|intact:EBI-28969419|ensembl:ENSP00000257604|ensembl:ENSP00000396526	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:trad1_human(display_long)|uniprotkb:TRAFD1(gene name)|psi-mi:TRAFD1(display_short)|uniprotkb:FLN29(gene name synonym)|uniprotkb:Protein FLN29(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSP00000257604|ensembl:ENSP00000396526|ensembl:ENST00000552890|ensembl:ENSP00000447340|refseq:NP_001137378.1|refseq:NP_006691.1|ensembl:ENSG00000135148(gene)|ensembl:ENST00000257604(transcript)|ensembl:ENST00000412615(transcript)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|rcsb pdb:2D9K	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hDY19qxNvWdsjDOoUEpuYfe0cdA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y6D0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-9679163|uniprotkb:Q8IZQ3|uniprotkb:Q9P085|ensembl:ENSP00000418813	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:selk_human(display_long)|uniprotkb:SELENOK(gene name)|psi-mi:SELENOK(display_short)|uniprotkb:SELK(gene name synonym)|uniprotkb:HSPC030(orf name)|uniprotkb:HSPC297(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_067060.2|ensembl:ENSG00000113811(gene)|ensembl:ENST00000495461(transcript)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045728"(respiratory burst after phagocytosis)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071639"(positive regulation of monocyte chemotactic protein-1 production)|go:"GO:2000406"(positive regulation of T cell migration)|interpro:IPR024491|rcsb pdb:6DO3	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:e0SoDHprfiTOiInNeRHt0mWfPWU9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y5M8	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355393|uniprotkb:Q8N2D8|uniprotkb:Q6P595|ensembl:ENSP00000418401|ensembl:ENSP00000503923	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:srprb_human(display_long)|uniprotkb:SRPRB(gene name)|psi-mi:SRPRB(display_short)|uniprotkb:PSEC0230(orf name)|uniprotkb:Protein APMCF1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_067026.3|ensembl:ENSG00000144867(gene)|ensembl:ENST00000466490(transcript)|ensembl:ENST00000678299(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|mint:Q9Y5M8|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|dip:DIP-50218N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pHUdnCvOhMRYIJg//OJ+SlCard49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y5A9	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2878081|uniprotkb:B4E1G7|uniprotkb:A6NKG4|uniprotkb:Q5VSZ9|uniprotkb:Q8TDH0|uniprotkb:Q9BUJ5|uniprotkb:A8K966|uniprotkb:D3DPM8|ensembl:ENSP00000362918|ensembl:ENSP00000444660	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ythd2_human(display_long)|uniprotkb:HGRG8(gene name synonym)|uniprotkb:CLL-associated antigen KW-14(gene name synonym)|uniprotkb:High-glucose-regulated protein 8(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-2(gene name synonym)|uniprotkb:YTHDF2(gene name)|psi-mi:YTHDF2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001166299.1|refseq:NP_001166599.1|refseq:NP_057342.2|ensembl:ENSG00000198492(gene)|ensembl:ENST00000373812(transcript)|ensembl:ENST00000542507(transcript)|go:"GO:0000932"(P-body)|go:"GO:0001556"(oocyte maturation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007049"(cell cycle)|go:"GO:0007276"(gamete generation)|go:"GO:0007284"(spermatogonial cell division)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0034063"(stress granule assembly)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045087"(innate immune response)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding)|go:"GO:0070925"(organelle assembly)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0098508"(endothelial to hematopoietic transition)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1903538"(regulation of meiotic cell cycle process involved in oocyte maturation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:2000232"(regulation of rRNA processing)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR007275(YT521-B-like protein)|mint:Q9Y5A9|rcsb pdb:4RDO|rcsb pdb:4WQN|rcsb pdb:4RDN	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:PF4C2t/728HqnrTyBQDJydH0G709606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y490	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2462036|uniprotkb:A6NMY0|uniprotkb:Q86YD0|uniprotkb:Q9NZQ2|uniprotkb:Q9UHH8|uniprotkb:Q9UPX3|intact:EBI-28967697|ensembl:ENSP00000316029	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tln1_human(display_long)|uniprotkb:TLN1(gene name)|psi-mi:TLN1(display_short)|uniprotkb:KIAA1027(gene name synonym)|uniprotkb:TLN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSP00000316029|refseq:NP_006280.3|ensembl:ENSG00000137076(gene)|ensembl:ENST00000314888(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:Q9Y490|rcsb pdb:1SYQ|rcsb pdb:2MWN|rcsb pdb:4DJ9|rcsb pdb:6R9T|reactome:R-HSA-114608|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381038|reactome:R-HSA-399955|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:C7FGaR2291KB6hBSloee5L8lYgA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y314	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051889|uniprotkb:Q96FD2|ensembl:ENSP00000470034	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:nosip_human(display_long)|uniprotkb:eNOS-interacting protein(gene name synonym)|uniprotkb:NOSIP(gene name)|psi-mi:NOSIP(display_short)|uniprotkb:CGI-25(orf name)|uniprotkb:E3 ubiquitin-protein ligase NOSIP(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase NOSIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001257889.1|refseq:NP_057037.1|ensembl:ENSG00000142546(gene)|ensembl:ENST00000596358(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016818(Nitric oxide synthase-interacting)|interpro:IPR031790|reactome:R-HSA-203754|refseq:XP_016882340.1|refseq:XP_016882341.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:vC1sjYkWe4QjRlwCJ3C5+EB8PcA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y285	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-725361|uniprotkb:Q9NSD8|uniprotkb:Q9Y4W8|uniprotkb:B4E363|ensembl:ENSP00000320309	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:syfa_human(display_long)|uniprotkb:CML33(gene name synonym)|uniprotkb:FARSA(gene name)|psi-mi:FARSA(display_short)|uniprotkb:FARS(gene name synonym)|uniprotkb:FARSLA(gene name synonym)|uniprotkb:FARSL(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase alpha subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004452.1|ensembl:ENSG00000179115(gene)|ensembl:ENST00000314606(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR002319(Phenylalanyl-tRNA synthetase, class IIc)|interpro:IPR004529(Phenylalanyl-tRNA synthetase, class IIc, alpha subunit)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR036390|interpro:IPR040586|interpro:IPR040724|interpro:IPR040725|mint:Q9Y285|rcsb pdb:3L4G|reactome:R-HSA-379716|dip:DIP-53610N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:FpOCk4Mzmsb2CnIUwUKg5nRg7/U9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y266	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-357298|ensembl:ENSP00000319664|uniprotkb:Q5QP31|uniprotkb:Q5QP35|uniprotkb:Q9H0N2|uniprotkb:Q9Y2B6|intact:EBI-2555945	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:nudc_human(display_long)|uniprotkb:NUDC(gene name)|psi-mi:NUDC(display_short)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000090273(gene)|ensembl:ENST00000321265(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:Q9Y266|rcsb pdb:3QOR|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0007080"(mitotic metaphase plate congression)|reactome:R-HSA-9696270|refseq:NP_006591.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:e1Q+/+VhG73ljCc3+ibG+RZNQUM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y237	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-714599|ensembl:ENSP00000362773|uniprotkb:Q5HYW6|uniprotkb:A8E0G6|uniprotkb:Q6IRW4|uniprotkb:Q0D2H3|uniprotkb:Q3MHV0|uniprotkb:Q52M21|uniprotkb:B3KXM0|uniprotkb:F5H1P5	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pin4_human(display_long)|uniprotkb:Parvulin-17(gene name synonym)|uniprotkb:Rotamase Pin4(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin4(gene name synonym)|uniprotkb:Parvulin-14(gene name synonym)|uniprotkb:Peptidyl-prolyl cis/trans isomerase EPVH(gene name synonym)|uniprotkb:PIN4(gene name)|psi-mi:PIN4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000102309(gene)|ensembl:ENST00000373669(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003681"(bent DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001164218.1|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006364"(rRNA processing)|go:"GO:0030684"(preribosome)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR043323|rcsb pdb:1EQ3|rcsb pdb:1FJD|rcsb pdb:3UI4|rcsb pdb:3UI5|rcsb pdb:3UI6|refseq:NP_006214.2|go:"GO:0005694"(chromosome)|dip:DIP-50838N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fqn1yVv3BoIxVdsY4VSzGFWWir09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UNX3	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2949703|ensembl:ENSP00000265100|ensembl:ENSP00000428177|ensembl:ENSP00000428223|ensembl:ENSP00000430147|uniprotkb:B3KY82|uniprotkb:D3DQM0	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rl26l_human(display_long)|uniprotkb:RPL26L1(gene name)|psi-mi:RPL26L1(display_short)|uniprotkb:RPL26P1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL24-like 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000037241(gene)|ensembl:ENST00000265100(transcript)|ensembl:ENST00000519239(transcript)|ensembl:ENST00000519974(transcript)|ensembl:ENST00000521476(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q9UNX3|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-2408557|refseq:NP_057177.1|refseq:XP_011532867.1|refseq:NP_001304909.1|refseq:NP_001304910.1|refseq:NP_001304911.1|refseq:XP_016865008.1|refseq:XP_016865009.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:dny/DWK4MvWD3FUJvW5+KGI3iJI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UNF1	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-725832|uniprotkb:O76058|uniprotkb:Q5BJF3|uniprotkb:Q8NAL6|uniprotkb:Q9H218|uniprotkb:Q9P0U9|uniprotkb:A6NMX0|uniprotkb:Q9UM52|ensembl:ENSP00000218439|ensembl:ENSP00000364193|ensembl:ENSP00000364198|ensembl:ENSP00000364209|ensembl:ENSP00000379526	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:magd2_human(display_long)|uniprotkb:MAGE-D2 antigen(gene name synonym)|uniprotkb:Breast cancer-associated gene 1 protein(gene name synonym)|uniprotkb:11B6(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated protein JCL-1(gene name synonym)|uniprotkb:MAGED2(gene name)|psi-mi:MAGED2(display_short)|uniprotkb:BCG1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_055414.2|refseq:NP_803182.1|refseq:NP_957516.1|ensembl:ENSG00000102316(gene)|ensembl:ENST00000218439(transcript)|ensembl:ENST00000375053(transcript)|ensembl:ENST00000375058(transcript)|ensembl:ENST00000375068(transcript)|ensembl:ENST00000396224(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007565"(female pregnancy)|go:"GO:0016020"(membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0070294"(renal sodium ion absorption)|interpro:IPR002190(MAGE protein)|interpro:IPR028810|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9UNF1|reactome:R-HSA-114608|dip:DIP-50722N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fXavezmKy58aGuVgzvDYjwNw3B89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UNE7	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:h4QyIM0TptgkQppPUgiKn68XjP49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UJS0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UII2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203|ensembl:ENSP00000494248	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:"Inhibitor of F(1)F(o)-ATPase"(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770(gene)|ensembl:ENSG00000285390(gene)|ensembl:ENST00000335514(transcript)|ensembl:ENST00000647074(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043532"(angiostatin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0140260"(mitochondrial proton-transporting ATP synthase complex binding)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|go:"GO:0051346"(negative regulation of hydrolase activity)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UHD1	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2550959|ensembl:ENSP00000319255|ensembl:ENSP00000496744|uniprotkb:Q9H3D6|uniprotkb:Q8WVL9|uniprotkb:B2R6P8|uniprotkb:Q6IN49	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:chrd1_human(display_long)|uniprotkb:CHP1(gene name synonym)|uniprotkb:CHORD domain-containing protein 1(gene name synonym)|uniprotkb:CHORDC1(gene name)|psi-mi:CHORDC1(display_short)|uniprotkb:Protein morgana(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000110172(gene)|ensembl:ENSG00000285023(gene)|ensembl:ENST00000320585(transcript)|ensembl:ENST00000646618(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0043531"(ADP binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:2000299"(negative regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007051(CHORD)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR039790|rcsb pdb:2YRT|go:"GO:1900034"(regulation of cellular response to heat)|refseq:NP_001137545.1|refseq:NP_036256.2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hlLw4jieLbD+CRQ/Nav7CR+YlUY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9P258	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-352547|uniprotkb:Q8IVL9|uniprotkb:Q9BSN6|uniprotkb:Q9NPV8|ensembl:ENSP00000364582|ensembl:ENSP00000364585|ensembl:ENSP00000486099|ensembl:ENSP00000486447	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rcc2_human(display_long)|uniprotkb:RCC2(gene name)|psi-mi:RCC2(display_short)|uniprotkb:KIAA1470(gene name synonym)|uniprotkb:TD60(gene name synonym)|uniprotkb:Telophase disk protein of 60 kDa(gene name synonym)|uniprotkb:RCC1-like protein TD-60(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001129676.1|refseq:NP_061185.1|ensembl:ENSG00000179051(gene)|ensembl:ENSG00000281540(gene)|ensembl:ENST00000375433(transcript)|ensembl:ENST00000375436(transcript)|ensembl:ENST00000628984(transcript)|ensembl:ENST00000631021(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034506"(chromosome, centromeric core domain)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051301"(cell division)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072356"(chromosome passenger complex localization to kinetochore)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1990023"(mitotic spindle midzone)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR028641|mint:Q9P258|rcsb pdb:5GWN|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:z9+0avftBLs4Q3ODFHLEmJtd57A9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NXS2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052839|uniprotkb:Q53HE4|uniprotkb:Q96F74|ensembl:ENSP00000012049	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:qpctl_human(display_long)|uniprotkb:Golgi-resident glutaminyl-peptide cyclotransferase(gene name synonym)|uniprotkb:isoQC(gene name synonym)|uniprotkb:QPCTL(gene name)|psi-mi:QPCTL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001156849.1|refseq:NP_060129.2|ensembl:ENSG00000011478(gene)|ensembl:ENST00000012049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016603"(glutaminyl-peptide cyclotransferase activity)|go:"GO:0017186"(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase)|interpro:IPR037457|interpro:IPR040234|rcsb pdb:3PB4|rcsb pdb:3PB6|rcsb pdb:3PB7|rcsb pdb:3PB8|rcsb pdb:3PB9|interpro:IPR007484(Peptidase M28)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:J4CsQuJYRh/8S2KDQQGzZh3Mra89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NWT6	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NSD9	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-353803|uniprotkb:B4DFM0|uniprotkb:O95708|uniprotkb:Q9NZZ6|uniprotkb:Q4ZFX1|uniprotkb:Q57ZJ5|ensembl:ENSP00000281828	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:syfb_human(display_long)|uniprotkb:FARSB(gene name)|psi-mi:FARSB(display_short)|uniprotkb:FARSLB(gene name synonym)|uniprotkb:FRSB(gene name synonym)|uniprotkb:Phenylalanyl-tRNA synthetase beta subunit(gene name synonym)|uniprotkb:HSPC173(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005678.3|refseq:XP_006712232.1|refseq:XP_011508768.1|ensembl:ENSG00000116120(gene)|ensembl:ENST00000281828(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004826"(phenylalanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006432"(phenylalanyl-tRNA aminoacylation)|go:"GO:0009328"(phenylalanine-tRNA ligase complex)|go:"GO:0016020"(membrane)|go:"GO:0051290"(protein heterotetramerization)|interpro:IPR004531(Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic)|interpro:IPR005146(B3/B4 tRNA-binding domain)|interpro:IPR005147(tRNA synthetase, B5)|interpro:IPR009061(Putative DNA binding)|interpro:IPR020825|interpro:IPR040659|interpro:IPR041616|rcsb pdb:3L4G|reactome:R-HSA-379716|refseq:XP_016858599.1|dip:DIP-32869N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:YgMUMEiw+jAUaDK5KomMWi66vn09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NS69	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1047508|intact:EBI-1180569|ensembl:ENSP00000216034	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tom22_human(display_long)|uniprotkb:TOMM22(gene name)|psi-mi:TOMM22(display_short)|uniprotkb:TOM22(gene name synonym)|uniprotkb:Translocase of outer membrane 22 kDa subunit homolog(gene name synonym)|uniprotkb:1C9-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_064628.1|ensembl:ENSG00000100216(gene)|ensembl:ENST00000216034(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR005683(Mitochondrial import translocase, subunit Tom22)|mint:Q9NS69|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:DI3BGFSB04B1/mMHJsBpOsCxrYk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NPF4	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1056510|uniprotkb:Q6IAC3|ensembl:ENSP00000206542	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:osgep_human(display_long)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP"(gene name synonym)|uniprotkb:OSGEP(gene name)|psi-mi:OSGEP(display_short)|uniprotkb:GCPL1(gene name synonym)|uniprotkb:O-sialoglycoprotein endopeptidase(gene name synonym)|uniprotkb:tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP(gene name synonym)|uniprotkb:N6-L-threonylcarbamoyladenine synthase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_060277.1|ensembl:ENSG00000092094(gene)|ensembl:ENST00000206542(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0046872"(metal ion binding)|go:"GO:0061711"("N(6)-L-threonylcarbamoyladenine synthase activity")|interpro:IPR000905(Peptidase M22, glycoprotease)|interpro:IPR017860|interpro:IPR017861|interpro:IPR034680|interpro:IPR043129|mint:Q9NPF4|rcsb pdb:6GWJ|reactome:R-HSA-6782315	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:gdWaUekKJ7WFXfPlaleW9Dpmsi89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9HCC0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9HB71	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1047302|uniprotkb:O60666|ensembl:ENSP00000356652|uniprotkb:B2ZWH2|uniprotkb:Q5R371|uniprotkb:B3KSF1|uniprotkb:Q5R370	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cybp_human(display_long)|uniprotkb:Siah-interacting protein(gene name synonym)|uniprotkb:S100A6-binding protein(gene name synonym)|uniprotkb:CACYBP(gene name)|psi-mi:CACYBP(display_short)|uniprotkb:S100A6BP(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:PNAS-107(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR007052(CS domain)|interpro:IPR007699(SGS)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR015120(Siah interacting protein, N terminal)|interpro:IPR037201|interpro:IPR037893|mint:Q9HB71|rcsb pdb:1X5M|rcsb pdb:2A25|rcsb pdb:2A26|go:"GO:0071277"(cellular response to calcium ion)|refseq:NP_001007215.1|refseq:NP_055227.1|ensembl:ENSG00000116161(gene)|ensembl:ENST00000367679(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0015631"(tubulin binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|refseq:XP_016856535.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:mvv1o19mLHBS3FDnATyOFsDoZvk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9HAC8	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-745871|uniprotkb:Q53HI3|uniprotkb:D3DR57|ensembl:ENSP00000359698	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ubtd1_human(display_long)|uniprotkb:UBTD1(gene name)|psi-mi:UBTD1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_079230.1|ensembl:ENSG00000165886(gene)|ensembl:ENST00000370664(transcript)|interpro:IPR000626(Ubiquitin)|interpro:IPR019956|interpro:IPR029071|interpro:IPR032752|interpro:IPR038169|interpro:IPR039869	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:P3QDDjw2RjE5kaJgtb5z6/Kmroc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9H9B4	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355861|uniprotkb:Q9HA53|uniprotkb:B3KPW3|uniprotkb:D3DQN2|ensembl:ENSP00000316905	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sfxn1_human(display_long)|uniprotkb:SFXN1(gene name)|psi-mi:SFXN1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_073591.2|refseq:NP_001309906.1|ensembl:ENSG00000164466(gene)|ensembl:ENST00000321442(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015825"(L-serine transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0042942"(D-serine transport)|go:"GO:0042945"(D-serine transmembrane transporter activity)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q9H9B4	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:n/i6d8Rt+xMOvu3BrZfc0VP0+Wk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9H0C8	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2620298|uniprotkb:B3KM39|ensembl:ENSP00000254654	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ilkap_human(display_long)|uniprotkb:ILKAP(gene name)|psi-mi:ILKAP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_110395.1|ensembl:ENSG00000132323(gene)|ensembl:ENST00000254654(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q9H0C8	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:iKH8FvITcNnqKYK8zIsijGhZllM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9BZZ5	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1048422|uniprotkb:O15441|uniprotkb:Q9Y4J7|uniprotkb:D3DR21|uniprotkb:B4DRJ2|uniprotkb:B4E283|uniprotkb:B4DGR0|ensembl:ENSP00000431391	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:api5_human(display_long)|uniprotkb:Fibroblast growth factor 2-interacting factor(gene name synonym)|uniprotkb:Protein XAGL(gene name synonym)|uniprotkb:Antiapoptosis clone 11 protein(gene name synonym)|uniprotkb:Cell migration-inducing gene 8 protein(gene name synonym)|uniprotkb:API5(gene name)|psi-mi:API5(display_short)|uniprotkb:MIG8(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001136402.1|refseq:NP_001136403.1|refseq:NP_006586.1|refseq:NP_001230676.1|ensembl:ENSG00000166181(gene)|ensembl:ENST00000531273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR008383(Apoptosis inhibitory 5)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q9BZZ5|rcsb pdb:3U0R|rcsb pdb:3V6A|rcsb pdb:6L4O	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:WYNbM5GNolgFNszccnMEanszDgU9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9BTT0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2685059|uniprotkb:Q5TB18|uniprotkb:Q8N1S4|uniprotkb:Q8WWW9|uniprotkb:B4E0I6|uniprotkb:E9PEA6|uniprotkb:Q5TB20|ensembl:ENSP00000463154	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:an32e_human(display_long)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:ANP32E(gene name)|psi-mi:ANP32E(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001129950.1|refseq:NP_001129951.1|refseq:NP_112182.1|refseq:NP_001267488.1|refseq:NP_001267489.1|ensembl:ENSG00000143401(gene)|ensembl:ENST00000583931(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043486"(histone exchange)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q9BTT0|rcsb pdb:4CAY|rcsb pdb:4NFT	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:byeFwwxqINXwewx0Gx/QXSyes8g9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9BS26	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-541644|uniprotkb:O60319|uniprotkb:Q5VWZ7|uniprotkb:Q6UW14|uniprotkb:Q8WX67|intact:EBI-1054855|uniprotkb:Q4VXC1|ensembl:ENSP00000262455	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:erp44_human(display_long)|uniprotkb:ERP44(gene name)|psi-mi:ERP44(display_short)|uniprotkb:UNQ532/PRO1075(orf name)|uniprotkb:TXNDC4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:KIAA0573(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000023318(gene)|ensembl:ENST00000262455(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009986"(cell surface)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|mint:Q9BS26|rcsb pdb:2R2J|rcsb pdb:5GU6|rcsb pdb:5GU7|rcsb pdb:5HQP|rcsb pdb:5XWM|reactome:R-HSA-6798695|go:"GO:0009100"(glycoprotein metabolic process)|refseq:NP_055866.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:TpwaFRifveb03iRPS2pEZve1kLA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9BQ61	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-744881|ensembl:ENSP00000242784	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:trir_human(display_long)|uniprotkb:TRIR(gene name)|psi-mi:TRIR(display_short)|uniprotkb:C19orf43(gene name synonym)|uniprotkb:Exoribonuclease TRIR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_076943.1|ensembl:ENSG00000123144(gene)|ensembl:ENST00000242784(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR038838|mint:Q9BQ61|refseq:NP_001316667.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8oDbNDhz5798Vmd+iPuLCh14ia09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q99961	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|dip:DIP-29452N|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360	-	-	crc64:6E5BE978BC955077	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q99714	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q99615	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-357552|ensembl:ENSP00000406463|uniprotkb:Q7Z784	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dnjc7_human(display_long)|uniprotkb:DNAJC7(gene name)|psi-mi:DNAJC7(display_short)|uniprotkb:TPR2(gene name synonym)|uniprotkb:TTC2(gene name synonym)|uniprotkb:Tetratricopeptide repeat protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000168259(gene)|ensembl:ENST00000457167(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR036869|reactome:R-HSA-3371453|refseq:NP_003306.3|refseq:XP_011523469.1|refseq:XP_011523470.1|refseq:XP_011523471.1|refseq:NP_001138238.1|refseq:XP_016880483.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:eZ1/nlVA9bOU/N3yrJ3pWrnM1P09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q99497	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1164361|uniprotkb:O14805|uniprotkb:Q6DR95|uniprotkb:Q7LFU2|uniprotkb:B2R4Z1|ensembl:ENSP00000340278|ensembl:ENSP00000366708|ensembl:ENSP00000366711|ensembl:ENSP00000418770|ensembl:ENSP00000465404	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:park7_human(display_long)|uniprotkb:PARK7(gene name)|psi-mi:PARK7(display_short)|uniprotkb:Oncogene DJ1(gene name synonym)|uniprotkb:Parkinsonism-associated deglycase(gene name synonym)|uniprotkb:Maillard deglycase(gene name synonym)|uniprotkb:Protein DJ-1(gene name synonym)|uniprotkb:Protein/nucleic acid deglycase DJ-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001116849.1|refseq:NP_009193.2|refseq:XP_005263481.1|go:"GO:0046295"(glycolate biosynthetic process)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050787"(detoxification of mercury ion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061727"(methylglyoxal catabolic process to lactate)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070994"(detection of oxidative stress)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098793"(presynapse)|go:"GO:0106044"(guanine deglycation)|go:"GO:0106045"(guanine deglycation, methylglyoxal removal)|go:"GO:0106046"(guanine deglycation, glyoxal removal)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:0140041"(cellular detoxification of methylglyoxal)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901671"(positive regulation of superoxide dismutase activity)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902903"(regulation of supramolecular fiber organization)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1903073"(negative regulation of death-inducing signaling complex assembly)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1903122"(negative regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1903168"(positive regulation of pyrroline-5-carboxylate reductase activity)|go:"GO:1903178"(positive regulation of tyrosine 3-monooxygenase activity)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903189"(glyoxal metabolic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1903200"(positive regulation of L-dopa decarboxylase activity)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903384"(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990422"("glyoxalase (glycolic acid-forming) activity")|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR002818(ThiJ/PfpI)|interpro:IPR006287(DJ-1)|interpro:IPR029062|go:"GO:1903197"(positive regulation of L-dopa biosynthetic process)|rcsb pdb:3B36|rcsb pdb:3B38|rcsb pdb:3B3A|rcsb pdb:3BWE|rcsb pdb:3CY6|rcsb pdb:3CYF|rcsb pdb:3CZ9|rcsb pdb:3CZA|rcsb pdb:3EZG|mint:Q99497|rcsb pdb:1J42|rcsb pdb:1P5F|rcsb pdb:3F71|rcsb pdb:1PDV|rcsb pdb:1PDW|rcsb pdb:1PE0|rcsb pdb:1Q2U|rcsb pdb:3SF8|rcsb pdb:1SOA|rcsb pdb:1UCF|rcsb pdb:2OR3|rcsb pdb:2R1T|rcsb pdb:2R1U|rcsb pdb:2R1V|rcsb pdb:4BTE|rcsb pdb:2RK3|rcsb pdb:2RK4|rcsb pdb:2RK6|ensembl:ENSG00000116288(gene)|ensembl:ENST00000338639(transcript)|ensembl:ENST00000377488(transcript)|ensembl:ENST00000377491(transcript)|ensembl:ENST00000493678(transcript)|ensembl:ENST00000493373(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002866"(positive regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006281"(DNA repair)|rcsb pdb:4MTC|rcsb pdb:4N0M|rcsb pdb:4N12|rcsb pdb:4OGF|rcsb pdb:4OQ4|rcsb pdb:4P2G|rcsb pdb:4P34|rcsb pdb:4P35|rcsb pdb:4P36|rcsb pdb:4RKW|rcsb pdb:4RKY|rcsb pdb:4S0Z|rcsb pdb:4ZGG|rcsb pdb:5IP5|rcsb pdb:5SY6|rcsb pdb:5SY9|rcsb pdb:5SYA|rcsb pdb:6AF5|rcsb pdb:6AF7|rcsb pdb:6AF9|rcsb pdb:6AFA|rcsb pdb:6AFB|rcsb pdb:6AFC|rcsb pdb:6AFD|rcsb pdb:6AFE|rcsb pdb:6AFF|rcsb pdb:6AFG|rcsb pdb:6AFH|rcsb pdb:6AFI|rcsb pdb:6AFJ|rcsb pdb:6AFL|rcsb pdb:6E5Z|rcsb pdb:6M8Z|rcsb pdb:7C62|reactome:R-HSA-3899300|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|rcsb pdb:4MNT|go:"GO:0006517"(protein deglycosylation)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007338"(single fertilization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009438"(methylglyoxal metabolic process)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016532"(superoxide dismutase copper chaperone activity)|go:"GO:0016570"(histone modification)|go:"GO:0016605"(PML body)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0030424"(axon)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0036470"(tyrosine 3-monooxygenase activator activity)|go:"GO:0036471"(cellular response to glyoxal)|go:"GO:0036478"(L-dopa decarboxylase activator activity)|go:"GO:0036524"(protein deglycase activity)|go:"GO:0036526"(peptidyl-cysteine deglycation)|go:"GO:0036527"(peptidyl-arginine deglycation)|go:"GO:0036528"(peptidyl-lysine deglycation)|go:"GO:0036529"(protein deglycation, glyoxal removal)|go:"GO:0036530"(protein deglycation, methylglyoxal removal)|go:"GO:0036531"(glutathione deglycation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0030073"(insulin secretion)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045340"(mercury ion binding)|dip:DIP-35515N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:i5ah4UPCf+4cD51ClZNggMFJMDo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q99426	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-764356|uniprotkb:O00111|uniprotkb:O00674|uniprotkb:O14728|uniprotkb:Q6FGY5|ensembl:ENSP00000221855	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tbcb_human(display_long)|uniprotkb:Tubulin-specific chaperone B(gene name synonym)|uniprotkb:Cytoskeleton-associated protein 1(gene name synonym)|uniprotkb:Cytoskeleton-associated protein CKAPI(gene name synonym)|uniprotkb:TBCB(gene name)|psi-mi:TBCB(display_short)|uniprotkb:CG22(gene name synonym)|uniprotkb:CKAP1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001272.2|refseq:NP_001287900.1|dip:DIP-34409N|ensembl:ENSG00000105254(gene)|ensembl:ENST00000221855(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007399"(nervous system development)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR000626(Ubiquitin)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR029071|interpro:IPR036859|reactome:R-HSA-389977|go:"GO:0030154"(cell differentiation)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:HHMamwtPQscu/rkhdarbQl6/hcw9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96LR5	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2129763|ensembl:ENSP00000379931|ensembl:ENSP00000401053	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2e2_human(display_long)|uniprotkb:UBE2E2(gene name)|psi-mi:UBE2E2(display_short)|uniprotkb:UBCH8(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E2(gene name synonym)|uniprotkb:Ubiquitin carrier protein E2(gene name synonym)|uniprotkb:UbcH8(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_689866.1|ensembl:ENSG00000182247(gene)|ensembl:ENST00000396703(transcript)|ensembl:ENST00000425792(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1Y6L|rcsb pdb:6W9A|reactome:R-HSA-983168|refseq:XP_005265489.1|dip:DIP-52704N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:wg1dG8oCGSZ7871YMQRSFEbmcEo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96IX5	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-954033|ensembl:ENSP00000311245|ensembl:ENSP00000337705|ensembl:ENSP00000358826|ensembl:ENSP00000358830|ensembl:ENSP00000358840|uniprotkb:B2R4N2|uniprotkb:D3DR92	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:atpmk_human(display_long)|uniprotkb:ATP5MK(gene name)|psi-mi:ATP5MK(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:ATP5MD(gene name synonym)|uniprotkb:DAPIT(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:HCV F-transactivated protein 2(gene name synonym)|uniprotkb:HCVFTP2(gene name synonym)|uniprotkb:USMG5(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:PD04912(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000173915(gene)|ensembl:ENST00000309579(transcript)|ensembl:ENST00000337003(transcript)|ensembl:ENST00000369811(transcript)|ensembl:ENST00000369815(transcript)|ensembl:ENST00000369825(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|mint:Q96IX5|refseq:NP_001193355.1|refseq:NP_001193356.1|refseq:NP_116136.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7ClNWlgeH39kD7E6oiQdkuj7Hag9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96I24	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96H79	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-3050460|ensembl:ENSP00000275766|uniprotkb:Q8WUD9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:zcchl_human(display_long)|uniprotkb:ZC3HAV1L(gene name)|psi-mi:ZC3HAV1L(display_short)|uniprotkb:C7orf39(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000146858(gene)|ensembl:ENST00000275766(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR026693|interpro:IPR036388|interpro:IPR041360|refseq:NP_542391.2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:2usjPyQ0uIzX1ZEleVqyaqcCtko9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96CX2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358358|ensembl:ENSP00000366694	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96C01	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-373319|uniprotkb:Q96SS3|ensembl:ENSP00000037869	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:f136a_human(display_long)|uniprotkb:FAM136A(gene name)|psi-mi:FAM136A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_116211.2|ensembl:ENSG00000035141(gene)|ensembl:ENST00000037869(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR008560(Protein of unknown function DUF842, eukaryotic)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:i9TSWgN6JC8fuAcFrlTU3IKBDHE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96B02	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-716589|uniprotkb:B4DIV1|uniprotkb:Q9H823|uniprotkb:Q9HAG6|uniprotkb:Q9NV07|uniprotkb:Q1XBE0|ensembl:ENSP00000473561	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ube2w_human(display_long)|uniprotkb:Ubiquitin-protein ligase W(gene name synonym)|uniprotkb:Ubiquitin carrier protein W(gene name synonym)|uniprotkb:UBE2W(gene name)|psi-mi:UBE2W(display_short)|uniprotkb:UBC16(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 16(gene name synonym)|uniprotkb:N-terminus-conjugating E2(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme W(gene name synonym)|uniprotkb:N-terminal E2 ubiquitin-conjugating enzyme(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001001481.2|refseq:NP_060769.4|refseq:NP_001257944.1|ensembl:ENSG00000104343(gene)|ensembl:ENST00000602593(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q96B02|rcsb pdb:2A7L|rcsb pdb:2MT6|reactome:R-HSA-8866652|reactome:R-HSA-983168|dip:DIP-52724N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:LPyzOCGN6u3e7wXby+nMbq09NS09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96AG4	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96A49	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10770179|uniprotkb:Q68CP1|uniprotkb:Q96C60|uniprotkb:Q96JQ6|uniprotkb:Q96T20|ensembl:ENSP00000369500	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:syap1_human(display_long)|uniprotkb:SYAP1(gene name)|psi-mi:SYAP1(display_short)|uniprotkb:BSD domain-containing signal transducer and Akt interactor protein(gene name synonym)|uniprotkb:PRO3113(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_116185.2|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|interpro:IPR005607(BSD)|interpro:IPR035925|rcsb pdb:1X3A|ensembl:ENSG00000169895(gene)|ensembl:ENST00000380155(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:+gHfLl7YaR8geuci2/cAYP8CiKA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q969T4	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-348496|ensembl:ENSP00000376215|ensembl:ENSP00000386788|ensembl:ENSP00000473623|ensembl:ENSP00000473639|uniprotkb:Q5U0R7|uniprotkb:Q7Z4W4|uniprotkb:B2RAD6|uniprotkb:D3DPG3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2e3_human(display_long)|uniprotkb:UBE2E3(gene name)|psi-mi:UBE2E3(display_short)|uniprotkb:UBCE4(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E3(gene name synonym)|uniprotkb:Ubiquitin carrier protein E3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-23 kDa(gene name synonym)|uniprotkb:UbcH9(gene name synonym)|uniprotkb:UBCH9(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006348.1|refseq:NP_872619.1|ensembl:ENSG00000170035(gene)|ensembl:ENST00000392415(transcript)|ensembl:ENST00000410062(transcript)|ensembl:ENST00000602710(transcript)|ensembl:ENST00000602959(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0040008"(regulation of growth)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|reactome:R-HSA-8866652|reactome:R-HSA-983168|refseq:NP_001265483.1|refseq:NP_001265484.1|refseq:XP_005246301.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1Z6f7pg9hkbmoQwMjdGtkhWP/9A9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q93045	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-714194|uniprotkb:O14952|uniprotkb:Q6PK68|ensembl:ENSP00000220876|uniprotkb:A8K9M2|uniprotkb:G3V110	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:stmn2_human(display_long)|uniprotkb:Superior cervical ganglion-10 protein(gene name synonym)|uniprotkb:STMN2(gene name)|psi-mi:STMN2(display_short)|uniprotkb:SCG10(gene name synonym)|uniprotkb:SCGN10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000104435(gene)|ensembl:ENST00000220876(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000956(Stathmin)|interpro:IPR026729|interpro:IPR030514|interpro:IPR036002|mint:Q93045|reactome:R-HSA-9696273|refseq:NP_008960.2|refseq:NP_001186143.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:tM3wU+n2JiO1Cp4YeaAOYgBCDDA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q92945	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1049099|uniprotkb:O00301|uniprotkb:Q59EZ9|uniprotkb:Q5U4P6|uniprotkb:Q9UNT5|uniprotkb:Q9UQH5|intact:EBI-5455671|ensembl:ENSP00000381216	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fubp2_human(display_long)|uniprotkb:KH type-splicing regulatory protein(gene name synonym)|uniprotkb:p75(gene name synonym)|uniprotkb:KHSRP(gene name)|psi-mi:KHSRP(display_short)|uniprotkb:FUBP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003676.2|ensembl:ENSG00000088247(gene)|ensembl:ENST00000398148(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0051028"(mRNA transport)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q92945|rcsb pdb:2HH2|rcsb pdb:2HH3|rcsb pdb:2JVZ|rcsb pdb:2OPU|rcsb pdb:2OPV|rcsb pdb:4B8T|reactome:R-HSA-380994|reactome:R-HSA-450604|dip:DIP-48484N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hlybJllTqSgPgtwwz3kc12zDYh49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q92688	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-762428|uniprotkb:O00655|uniprotkb:P78458|uniprotkb:P78459|uniprotkb:B2R9C7|ensembl:ENSP00000345848	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:an32b_human(display_long)|uniprotkb:Acidic protein rich in leucines(gene name synonym)|uniprotkb:Silver-stainable protein SSP29(gene name synonym)|uniprotkb:ANP32B(gene name)|psi-mi:ANP32B(display_short)|uniprotkb:APRIL(gene name synonym)|uniprotkb:PHAPI2(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006392.1|ensembl:ENSG00000136938(gene)|ensembl:ENST00000339399(transcript)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048839"(inner ear development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q92688|rcsb pdb:2ELL|rcsb pdb:2RR6|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8eu0C8oHWUrZ28F2fIup9o5MDYk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q92530	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-945916|uniprotkb:A0AVQ9|uniprotkb:Q9H4I1|uniprotkb:D3DVW3|ensembl:ENSP00000327704|ensembl:ENSP00000338039	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:psmf1_human(display_long)|uniprotkb:PSMF1(gene name)|psi-mi:PSMF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006805.2|refseq:NP_848693.2|refseq:NP_001310336.1|ensembl:ENSG00000125818(gene)|ensembl:ENST00000333082(transcript)|ensembl:ENST00000335877(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070628"(proteasome binding)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|interpro:IPR013886(PI31 proteasome regulator)|interpro:IPR021625|rcsb pdb:2VT8|rcsb pdb:4OUH|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:QufCMzFs9wZBQO5l4iVOfn4dnvc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8WWK9	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1221087|uniprotkb:Q9HC49|uniprotkb:Q9NVG4|uniprotkb:A2BDE0|uniprotkb:A5YM58|uniprotkb:Q3KRA5|uniprotkb:Q5VXB4|uniprotkb:Q8IWV5|uniprotkb:Q8IWV6|uniprotkb:Q96FH9|uniprotkb:Q9H012|uniprotkb:Q9H0D0|uniprotkb:Q9H988|uniprotkb:B4DR35|uniprotkb:E9PD90|intact:EBI-11054734|ensembl:ENSP00000367276	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ckap2_human(display_long)|uniprotkb:CKAP2(gene name)|psi-mi:CKAP2(display_short)|uniprotkb:LB1(gene name synonym)|uniprotkb:TMAP(gene name synonym)|uniprotkb:Tumor- and microtubule-associated protein(gene name synonym)|uniprotkb:CTCL tumor antigen se20-10(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001273615.1|refseq:NP_001273616.1|refseq:NP_001091995.1|refseq:NP_060674.3|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR026165|interpro:IPR029197|mint:Q8WWK9|ensembl:ENSG00000136108(gene)|ensembl:ENST00000378037(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:17/ce51AUyDvCpdnm50uT/LSY7w9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8WWC4	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042937|ensembl:ENSP00000295079|ensembl:ENSP00000376111|uniprotkb:Q658V9|uniprotkb:Q9H671	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:maip1_human(display_long)|uniprotkb:MAIP1(gene name)|psi-mi:MAIP1(display_short)|uniprotkb:C2orf47(gene name synonym)|uniprotkb:Matrix AAA peptidase-interacting protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000162972(gene)|ensembl:ENST00000295079(transcript)|ensembl:ENST00000392290(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0032979"(protein insertion into mitochondrial inner membrane from matrix)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043022"(ribosome binding)|go:"GO:0051204"(protein insertion into mitochondrial membrane)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|mint:Q8WWC4|reactome:R-HSA-8949664|refseq:NP_078796.2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:kQCnnlC1WF95Jb2djLyrYldRikg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8WU90	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042636|uniprotkb:Q5QTQ4|uniprotkb:Q8WZ06|uniprotkb:Q9NUZ3|uniprotkb:Q9P079|uniprotkb:Q9NZ37|uniprotkb:B4DMW2|uniprotkb:D3DPG7|ensembl:ENSP00000338788	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:zc3hf_human(display_long)|uniprotkb:ZC3H15(gene name)|psi-mi:ZC3H15(display_short)|uniprotkb:DFRP1(gene name synonym)|uniprotkb:LEREPO4(gene name synonym)|uniprotkb:DRG family-regulatory protein 1(gene name synonym)|uniprotkb:Likely ortholog of mouse immediate early response erythropoietin 4(gene name synonym)|uniprotkb:HSPC303(orf name)|uniprotkb:HT010(orf name)|uniprotkb:MSTP012(orf name)|uniprotkb:PP730(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_060941.2|ensembl:ENSG00000065548(gene)|ensembl:ENST00000337859(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR032378|interpro:IPR036855|interpro:IPR041367|mint:Q8WU90	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:MrcssHMHDoQKqsIXdhfMWOnHlBY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8TE77-5	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769799	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:q8te77-5(display_long)|uniprotkb:SSH-like protein 3(gene name synonym)|uniprotkb:SSH3(gene name)|psi-mi:SSH3(display_short)|uniprotkb:SSH3L(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	intact:EBI-8743776(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fJ9gnA4S+rVJjF8vNbZzoYosGP49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8N490-2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769878|ensembl:ENSP00000248451	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:q8n490-2(display_long)|uniprotkb:PNKD(gene name)|psi-mi:PNKD(display_short)|uniprotkb:KIAA1184(gene name synonym)|uniprotkb:MR1(gene name synonym)|uniprotkb:TAHCCP2(gene name synonym)|uniprotkb:Myofibrillogenesis regulator 1(gene name synonym)|uniprotkb:Paroxysmal nonkinesiogenic dyskinesia protein(gene name synonym)|uniprotkb:Trans-activated by hepatitis C virus core protein 2(gene name synonym)|uniprotkb:FKSG19(orf name)|uniprotkb:UNQ2491/PRO5778(orf name)|uniprotkb:MR-1S(isoform synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000127838(gene)|ensembl:ENST00000248451(transcript)|intact:EBI-746368(isoform-parent)|uniprotkb:Q8N490-2(isoform-parent)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:cpTDxscb3w5klM/N5tkYzkkJcI89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q8N1F7	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pkk5pooUC4yQShpqjiwNLddfy149606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q86X55	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2339854|uniprotkb:A6NN38|ensembl:ENSP00000325690	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:carm1_human(display_long)|uniprotkb:CARM1(gene name)|psi-mi:CARM1(display_short)|uniprotkb:PRMT4(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 4(gene name synonym)|uniprotkb:Coactivator-associated arginine methyltransferase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_954592.1|refseq:XP_005259765.1|dip:DIP-44071N|ensembl:ENSG00000142453(gene)|ensembl:ENST00000327064(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0034971"(histone H3-R17 methylation)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0035642"("histone methyltransferase activity (H3-R17 specific)")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020989|interpro:IPR025799|interpro:IPR029063|mint:Q86X55|rcsb pdb:2Y1W|rcsb pdb:2Y1X|rcsb pdb:4IKP|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5DXJ|rcsb pdb:5U4X|rcsb pdb:6ARJ|rcsb pdb:6ARV|rcsb pdb:6D2L|rcsb pdb:6DVR|rcsb pdb:6IZQ|rcsb pdb:6S70|rcsb pdb:6S71|rcsb pdb:6S74|rcsb pdb:6S77|rcsb pdb:6S79|rcsb pdb:6S7A|rcsb pdb:6S7B|rcsb pdb:6S7C|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-6804114|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|go:"GO:0051591"(response to cAMP)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1x1bUjqcA/ZpmrSsSM545ReYH2A9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q86VP6	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9UG63	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2959697|ensembl:ENSP00000287844|uniprotkb:Q96TE8|uniprotkb:O60864|uniprotkb:Q75MJ0|uniprotkb:Q75MJ1	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:abcf2_human(display_long)|uniprotkb:ABCF2(gene name)|psi-mi:ABCF2(display_short)|uniprotkb:Iron-inhibited ABC transporter 2(gene name synonym)|uniprotkb:HUSSY-18(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000033050(gene)|ensembl:ENST00000287844(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|mint:Q9UG63|go:"GO:0016020"(membrane)|refseq:NP_005683.2|refseq:NP_009120.1|refseq:XP_016867128.1|refseq:XP_016867129.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:TdGWfZ4OYohgxKLL1uyz7X+FWmQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q6P1M0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P13693	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1783169|uniprotkb:Q6YLS2|uniprotkb:Q7Z4J4|uniprotkb:Q96EE2|uniprotkb:Q9UC70|intact:EBI-1058458|uniprotkb:B2R7E5|intact:EBI-5772926|uniprotkb:Q8TBK7|ensembl:ENSP00000431872	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tctp_human(display_long)|uniprotkb:TPT1(gene name)|psi-mi:TPT1(display_short)|uniprotkb:p23(gene name synonym)|uniprotkb:Histamine-releasing factor(gene name synonym)|uniprotkb:Fortilin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003286.1|refseq:NP_001273202.1|dip:DIP-40097N|ensembl:ENSG00000133112(gene)|ensembl:ENST00000530705(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0009615"(response to virus)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000384"(negative regulation of ectoderm development)|interpro:IPR011057(Mss4-like)|interpro:IPR011323(Mss4/translationally controlled tumour-associated TCTP)|interpro:IPR018103|interpro:IPR018105|interpro:IPR034737|mint:P13693|rcsb pdb:1YZ1|rcsb pdb:2HR9|rcsb pdb:3EBM|rcsb pdb:4Z9V|rcsb pdb:5O9L|rcsb pdb:5O9M|rcsb pdb:6IZB|rcsb pdb:6IZE	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1RijAyNqyKFL9LvKa9wbYtC4fRo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9BSD7	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2689235|ensembl:ENSP00000355587	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ntpcr_human(display_long)|uniprotkb:Nucleoside triphosphate phosphohydrolase(gene name synonym)|uniprotkb:NTPCR(gene name)|psi-mi:NTPCR(display_short)|uniprotkb:C1orf57(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_115700.1|interpro:IPR027417|mint:Q9BSD7|rcsb pdb:2I3B|ensembl:ENSG00000135778(gene)|ensembl:ENST00000366628(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016020"(membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004948(Protein of unknown function DUF265)|refseq:NP_001316382.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:tJoP+XQzoa4urq6g1rdZhMWO49g9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P11441	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356983|uniprotkb:Q5HY80|ensembl:ENSP00000358674	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ubl4a_human(display_long)|uniprotkb:UBL4A(gene name)|psi-mi:UBL4A(display_short)|uniprotkb:GDX(gene name synonym)|uniprotkb:DXS254E(gene name synonym)|uniprotkb:UBL4(gene name synonym)|uniprotkb:Ubiquitin-like protein GDX(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_055050.1|ensembl:ENSG00000102178(gene)|ensembl:ENST00000369660(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016020"(membrane)|go:"GO:0019787"(ubiquitin-like protein transferase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR041421|interpro:IPR044724|mint:P11441|rcsb pdb:2DZI|rcsb pdb:4WWR|rcsb pdb:4X86|reactome:R-HSA-9609523	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:euKOrDRC1mx0s2QVY95010PRaIg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q58FF8	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2961708	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:h90b2_human(display_long)|uniprotkb:HSP90AB2P(gene name)|psi-mi:HSP90AB2P(display_short)|uniprotkb:HSP90BB(gene name synonym)|uniprotkb:Heat shock protein 90-beta b(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:SntF/u+V170yoKZScA9O/5BL3Ps9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q53H12	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2269837|uniprotkb:Q75KN1|uniprotkb:Q96GC3|uniprotkb:Q9NP48|ensembl:ENSP00000496789|ensembl:ENSP00000497280|ensembl:ENSP00000498112|ensembl:ENSP00000458417	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:agk_human(display_long)|uniprotkb:AGK(gene name)|psi-mi:AGK(display_short)|uniprotkb:MULK(gene name synonym)|uniprotkb:Multiple substrate lipid kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:XP_011514699.1|refseq:NP_060708.1|ensembl:ENSG00000006530(gene)|ensembl:ENST00000575872(transcript)|ensembl:ENST00000648068(transcript)|ensembl:ENST00000649286(transcript)|ensembl:ENST00000650547(transcript)|go:"GO:0001727"(lipid kinase activity)|go:"GO:0001729"(ceramide kinase activity)|go:"GO:0003951"(NAD+ kinase activity)|go:"GO:0004143"(diacylglycerol kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042721"(TIM22 mitochondrial import inner membrane insertion complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045039"(protein insertion into mitochondrial inner membrane)|go:"GO:0046486"(glycerolipid metabolic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0047620"(acylglycerol kinase activity)|go:"GO:0102773"(dihydroceramide kinase activity)|interpro:IPR001206(Diacylglycerol kinase, catalytic region)|interpro:IPR016064(ATP-NAD kinase, PpnK-type)|interpro:IPR017438(ATP-NAD kinase, PpnK-type, alpha/beta)|go:"GO:0005743"(mitochondrial inner membrane)|ensembl:ENSG00000262327(gene)|rcsb pdb:7CGP|reactome:R-HSA-1483206|reactome:R-HSA-6802952|mint:Q53H12	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:aUz/aYnkviiUE/ijNEddfOQmjZQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q53GQ0	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2963255|uniprotkb:Q96EA9|ensembl:ENSP00000278353|uniprotkb:A8K9B0|uniprotkb:Q9Y6G8|uniprotkb:Q96JU2|uniprotkb:D3DR23	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dhb12_human(display_long)|uniprotkb:HSD17B12(gene name)|psi-mi:HSD17B12(display_short)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:SDR12C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 1(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000149084(gene)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0009923"(fatty acid elongase complex)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0050062"(long-chain-fatty-acyl-CoA reductase activity)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|ensembl:ENST00000278353(transcript)|go:"GO:0102339"(3-oxo-arachidoyl-CoA reductase activity)|go:"GO:0102341"(3-oxo-lignoceroyl-CoA reductase activity)|go:"GO:0102342"(3-oxo-cerotoyl-CoA reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q53GQ0|reactome:R-HSA-193048|reactome:R-HSA-75876|go:"GO:0102340"(3-oxo-behenoyl-CoA reductase activity)|refseq:NP_057226.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:2R2pFY0c9yRuCvLU2J8n2urR+0o9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P22392	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-713693|ensembl:ENSP00000376886|ensembl:ENSP00000421064|ensembl:ENSP00000425581|ensembl:ENSP00000426901|ensembl:ENSP00000426976|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000243678(gene)|ensembl:ENST00000393190(transcript)|ensembl:ENST00000503064(transcript)|ensembl:ENST00000512737(transcript)|ensembl:ENST00000513177(transcript)|ensembl:ENST00000514264(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|dip:DIP-50179N|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|reactome:R-HSA-499943|reactome:R-HSA-6798695|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q16181	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15637	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15417	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2371691|uniprotkb:B4DFK6|uniprotkb:B4DP09|uniprotkb:F8WA86|uniprotkb:Q6FHA7|ensembl:ENSP00000359225	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cnn3_human(display_long)|uniprotkb:CNN3(gene name)|psi-mi:CNN3(display_short)|uniprotkb:Calponin, acidic isoform(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001830.1|refseq:NP_001272984.1|refseq:NP_001272985.1|refseq:XP_016855734.1|ensembl:ENSG00000117519(gene)|ensembl:ENST00000370206(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:UgeW769u9WgYLYNzTZ50xQqB5I09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15369	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15365	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15185	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1049387|uniprotkb:Q8WU70|intact:EBI-9357271|uniprotkb:B4DHP2|uniprotkb:B4DP11|uniprotkb:B4DP21|uniprotkb:A8K7D0|ensembl:ENSP00000262033	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tebp_human(display_long)|uniprotkb:Cytosolic prostaglandin E2 synthase(gene name synonym)|uniprotkb:Telomerase-binding protein p23(gene name synonym)|uniprotkb:Progesterone receptor complex p23(gene name synonym)|uniprotkb:PTGES3(gene name)|psi-mi:PTGES3(display_short)|uniprotkb:P23(gene name synonym)|uniprotkb:TEBP(gene name synonym)|uniprotkb:Hsp90 co-chaperone(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001269530.1|refseq:NP_001269531.1|refseq:NP_001269532.1|refseq:NP_001269533.1|refseq:NP_001269534.1|refseq:NP_006592.3|dip:DIP-279N|ensembl:ENSG00000110958(gene)|ensembl:ENST00000262033(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043588"(skin development)|go:"GO:0050220"(prostaglandin-E synthase activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060430"(lung saccule development)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|mint:Q15185|rcsb pdb:1EJF|reactome:R-HSA-2162123|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|rcsb pdb:1LG0	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:6NuM7BPG39XzwqdKBCr74uuumCo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15181	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-712298|ensembl:ENSP00000362329|uniprotkb:Q2M348|uniprotkb:Q5SQT7|uniprotkb:Q6P7P4|uniprotkb:Q9UQJ5|uniprotkb:Q9Y5B1	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ipyr_human(display_long)|uniprotkb:Pyrophosphate phospho-hydrolase(gene name synonym)|uniprotkb:PPA1(gene name)|psi-mi:PPA1(display_short)|uniprotkb:IOPPP(gene name synonym)|uniprotkb:PP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000180817(gene)|ensembl:ENST00000373232(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q15181|rcsb pdb:6C45|rcsb pdb:7BTN|rcsb pdb:7CMO|reactome:R-HSA-379716|reactome:R-HSA-71737|refseq:NP_066952.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1094gn9aeisgfDUhIroRn2iqom49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15084	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:411bo7TdfeCtMvUqyBb7bofi5To9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15056	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-748492|uniprotkb:A8K3R1|uniprotkb:D3DXF6|uniprotkb:D3DXF8|ensembl:ENSP00000265753	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:if4h_human(display_long)|uniprotkb:Williams-Beuren syndrome chromosomal region 1 protein(gene name synonym)|uniprotkb:EIF4H(gene name)|psi-mi:EIF4H(display_short)|uniprotkb:WBSCR1(gene name synonym)|uniprotkb:KIAA0038(gene name synonym)|uniprotkb:WSCR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_071496.1|refseq:NP_114381.1|ensembl:ENSG00000106682(gene)|ensembl:ENST00000265753(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0019953"(sexual reproduction)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034229|interpro:IPR035979|mint:Q15056|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:dNPoAzwFD5lFwCMnRl0cbXM3j8s9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15046	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356367|uniprotkb:A8MSK1|uniprotkb:Q9HB23|uniprotkb:O14946|uniprotkb:Q96J25|ensembl:ENSP00000303043|uniprotkb:D3DUK4	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:syk_human(display_long)|uniprotkb:KARS1(gene name)|psi-mi:KARS1(display_short)|uniprotkb:KARS(gene name synonym)|uniprotkb:KIAA0070(gene name synonym)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001123561.1|refseq:NP_005539.1|go:"GO:0016597"(amino acid binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0005739"(mitochondrion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018149|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR034762|interpro:IPR044136|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:Q15046|go:"GO:0006430"(lysyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|rcsb pdb:3BJU|rcsb pdb:4DPG|go:"GO:0010165"(response to X-ray)|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:6CHD|rcsb pdb:6ILD|rcsb pdb:6ILH|rcsb pdb:7EA9|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|ensembl:ENSG00000065427(gene)|ensembl:ENST00000302445(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0003877"(ATP adenylyltransferase activity)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|dip:DIP-29725N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:YLjIdoUW7DiNp+Pj1OPg8jhnC5w9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q15019	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N	-	-	crc64:12CCBBE30806F92F	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q14974	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q14739	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q14657	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052105|uniprotkb:Q5HY39|uniprotkb:Q8IZ78|ensembl:ENSP00000349923	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:lage3_human(display_long)|uniprotkb:Protein ITBA2(gene name synonym)|uniprotkb:Protein ESO-3(gene name synonym)|uniprotkb:ITBA2(gene name synonym)|uniprotkb:LAGE3(gene name)|psi-mi:LAGE3(display_short)|uniprotkb:DXS9879E(gene name synonym)|uniprotkb:ESO3(gene name synonym)|uniprotkb:L antigen family member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006005.2|ensembl:ENSG00000196976(gene)|ensembl:ENST00000357360(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008033"(tRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070525"(tRNA threonylcarbamoyladenosine metabolic process)|interpro:IPR015419(Transcription factor Pcc1)|rcsb pdb:6GWJ|reactome:R-HSA-6782315	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:i85i7GnA4k4+zsftYKYMk+xWAFM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q14566	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-374900|uniprotkb:Q13504|uniprotkb:Q99859|uniprotkb:B2R6H2|ensembl:ENSP00000264156	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mcm6_human(display_long)|uniprotkb:MCM6(gene name)|psi-mi:MCM6(display_short)|uniprotkb:p105MCM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENST00000264156(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0042555"(MCM complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071162"(CMG complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902969"(mitotic DNA replication)|ensembl:ENSG00000076003(gene)|reactome:R-HSA-68962|reactome:R-HSA-69052|interpro:IPR008049(MCM protein 6)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041024|interpro:IPR041562|interpro:IPR001208(MCM)|mint:Q14566|rcsb pdb:2KLQ|rcsb pdb:2LE8|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|refseq:NP_005906.2|dip:DIP-31727N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:gVpEwgfSwwxvP2T2CvCzIukthY49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q14166	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-923010|uniprotkb:Q9UGU3|intact:EBI-1056800|uniprotkb:Q20WK5|ensembl:ENSP00000216129	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ttl12_human(display_long)|uniprotkb:TTLL12(gene name)|psi-mi:TTLL12(display_short)|uniprotkb:KIAA0153(gene name synonym)|uniprotkb:Inactive tubulin--tyrosine ligase-like protein 12(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_055955.1|ensembl:ENSG00000100304(gene)|ensembl:ENST00000216129(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0015631"(tubulin binding)|go:"GO:0030496"(midbody)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045087"(innate immune response)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:1990889"(H4K20me3 modified histone binding)|interpro:IPR004344(Tubulin-tyrosine ligase)|interpro:IPR027749|reactome:R-HSA-8955332	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:MXpuEK/k1S+fNxRGLpFGTO2YH2g9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q13526	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-714158|uniprotkb:Q53X75|ensembl:ENSP00000247970|ensembl:ENSP00000466962|uniprotkb:A8K4V9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pin1_human(display_long)|uniprotkb:Rotamase Pin1(gene name synonym)|uniprotkb:Peptidyl-prolyl cis-trans isomerase Pin1(gene name synonym)|uniprotkb:PIN1(gene name)|psi-mi:PIN1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000127445(gene)|ensembl:ENST00000247970(transcript)|ensembl:ENST00000588695(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0016859"(cis-trans isomerase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048156"(tau protein binding)|go:"GO:0050808"(synapse organization)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0060393"(regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:2000146"(negative regulation of cell motility)|interpro:IPR000297(Peptidyl-prolyl cis-trans isomerase, PpiC-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR023058|interpro:IPR036020|mint:Q13526|rcsb pdb:1F8A|rcsb pdb:1I6C|rcsb pdb:1I8G|rcsb pdb:1I8H|rcsb pdb:1NMV|rcsb pdb:1NMW|rcsb pdb:1PIN|rcsb pdb:1ZCN|rcsb pdb:2F21|rcsb pdb:2ITK|rcsb pdb:2KBU|rcsb pdb:2KCF|rcsb pdb:2LB3|rcsb pdb:2M8I|rcsb pdb:2M8J|rcsb pdb:2M9E|rcsb pdb:2M9F|rcsb pdb:2M9I|rcsb pdb:2M9J|rcsb pdb:2N1O|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJA|rcsb pdb:7NRK|rcsb pdb:7NRL|reactome:R-HSA-1169408|reactome:R-HSA-5668599|reactome:R-HSA-6804756|reactome:R-HSA-6811555|reactome:R-HSA-936440|rcsb pdb:2RUC|rcsb pdb:2RUD|rcsb pdb:2RUQ|rcsb pdb:2RUR|rcsb pdb:2XP3|rcsb pdb:2XP4|rcsb pdb:2XP5|rcsb pdb:2XP6|rcsb pdb:2XP7|rcsb pdb:2XP8|rcsb pdb:2XP9|rcsb pdb:2XPA|rcsb pdb:2XPB|rcsb pdb:2ZQS|rcsb pdb:2ZQT|rcsb pdb:2ZQU|rcsb pdb:2ZQV|rcsb pdb:2ZR4|rcsb pdb:2Q5A|rcsb pdb:2ZR5|rcsb pdb:2ZR6|rcsb pdb:3I6C|rcsb pdb:4TYO|rcsb pdb:4U84|rcsb pdb:4U85|rcsb pdb:4U86|rcsb pdb:5B3W|rcsb pdb:5B3X|rcsb pdb:5B3Y|rcsb pdb:5B3Z|rcsb pdb:5BMY|rcsb pdb:5GPH|rcsb pdb:5UY9|rcsb pdb:5VTI|rcsb pdb:5VTJ|rcsb pdb:5VTK|rcsb pdb:6DUN|rcsb pdb:6O33|rcsb pdb:6O34|rcsb pdb:6SVC|rcsb pdb:6SVE|rcsb pdb:6SVH|rcsb pdb:6VAJ|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:4TNS|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:3IKD|rcsb pdb:3IKG|rcsb pdb:3JYJ|rcsb pdb:3KAB|rcsb pdb:3KAC|rcsb pdb:3KAD|rcsb pdb:3KAF|rcsb pdb:3KAG|rcsb pdb:3KAH|rcsb pdb:3KAI|rcsb pdb:3KCE|rcsb pdb:3NTP|rcsb pdb:3ODK|rcsb pdb:3OOB|rcsb pdb:3TC5|rcsb pdb:3TCZ|rcsb pdb:3TDB|rcsb pdb:3WH0|rcsb pdb:4GWT|rcsb pdb:4GWV|rcsb pdb:3IK8|rcsb pdb:4QIB|refseq:NP_006212.1|dip:DIP-29306N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:FICkSpcBgvSDFW4iY1Etik85xNo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q13155	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-745226|uniprotkb:Q75MR1|uniprotkb:Q96CZ5|uniprotkb:Q9P1L2|ensembl:ENSP00000223029|uniprotkb:F8W950	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:aimp2_human(display_long)|uniprotkb:Protein JTV-1(gene name synonym)|uniprotkb:AIMP2(gene name)|psi-mi:AIMP2(display_short)|uniprotkb:PRO0992(orf name)|uniprotkb:JTV1(gene name synonym)|uniprotkb:Multisynthase complex auxiliary component p38(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006294.2|ensembl:ENSG00000106305(gene)|ensembl:ENST00000223029(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903632"(positive regulation of aminoacyl-tRNA ligase activity)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR031889|interpro:IPR036282|interpro:IPR041503|interpro:IPR042360|mint:Q13155|rcsb pdb:4DPG|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:5A1N|rcsb pdb:5A34|rcsb pdb:5A5H|rcsb pdb:5Y6L|rcsb pdb:6ILD|rcsb pdb:6IY6|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-34421N|refseq:NP_001313536.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:VEBmJjo6t3dBY6mKpmUyVLamJFQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q13148	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q12931	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q08J23	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1642839|intact:EBI-2839052|uniprotkb:A8K529|uniprotkb:B3KP09|uniprotkb:G3V1R4|uniprotkb:Q9BVN4|uniprotkb:Q9H858|uniprotkb:Q9NXD9|uniprotkb:B2RNR4|intact:EBI-2556652|uniprotkb:B4DQW2|ensembl:ENSP00000264670	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:nsun2_human(display_long)|uniprotkb:NSUN2(gene name)|psi-mi:NSUN2(display_short)|uniprotkb:SAKI(gene name synonym)|uniprotkb:TRM4(gene name synonym)|uniprotkb:NOL1/NOP2/Sun domain family member 2(gene name synonym)|uniprotkb:tRNA methyltransferase 4 homolog(gene name synonym)|uniprotkb:Substrate of AIM1/Aurora kinase B(gene name synonym)|uniprotkb:Myc-induced SUN domain-containing protein(gene name synonym)|uniprotkb:"mRNA cytosine C(5)-methyltransferase"(gene name synonym)|uniprotkb:"tRNA cytosine C(5)-methyltransferase"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001180384.1|refseq:NP_060225.4|dip:DIP-52456N|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0006400"(tRNA modification)|go:"GO:0007286"(spermatid development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016428"("tRNA (cytosine-5-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0033313"(meiotic cell cycle checkpoint signaling)|go:"GO:0033391"(chromatoid body)|go:"GO:0036416"(tRNA stabilization)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0051301"(cell division)|go:"GO:0062152"("mRNA (cytidine-5-)-methyltransferase activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0080009"(mRNA methylation)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR023267|interpro:IPR023270|interpro:IPR029063|mint:Q08J23|reactome:R-HSA-6782315|ensembl:ENSG00000037474(gene)|ensembl:ENST00000264670(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001510"(RNA methylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:k3hK/9cjuy5c4PyDGgCt0LsVtdo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q07065	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q06830	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q06203	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-3920254|ensembl:ENSP00000264220	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pur1_human(display_long)|uniprotkb:PPAT(gene name)|psi-mi:PPAT(display_short)|uniprotkb:GPAT(gene name synonym)|uniprotkb:Glutamine phosphoribosylpyrophosphate amidotransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000128059(gene)|ensembl:ENST00000264220(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001822"(kidney development)|go:"GO:0004044"(amidophosphoribosyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0007595"(lactation)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060135"(maternal process involved in female pregnancy)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005854(Amidophosphoribosyl transferase)|interpro:IPR017932|interpro:IPR029055|interpro:IPR029057|interpro:IPR035584|mint:Q06203|reactome:R-HSA-73817|refseq:NP_002694.3	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:W+6JIL0Nlil+ZMhxjlmySnQkqZE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q05682	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q02978	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359174|uniprotkb:O75537|uniprotkb:Q969P7|ensembl:ENSP00000225665|uniprotkb:F5GY65	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:m2om_human(display_long)|uniprotkb:SLC25A11(gene name)|psi-mi:SLC25A11(display_short)|uniprotkb:SLC20A4(gene name synonym)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003553.2|go:"GO:0071423"(malate transmembrane transport)|interpro:IPR018108|interpro:IPR023395|mint:Q02978|reactome:R-HSA-70263|ensembl:ENSG00000108528(gene)|ensembl:ENST00000225665(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015367"("oxoglutarate:malate antiporter activity")|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:TPeF6k/rQq+WJ9omeDK4V6NY4/o9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q02790	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1047444|uniprotkb:D3DUQ1|uniprotkb:Q9UCP1|uniprotkb:Q9UCV7|ensembl:ENSP00000001008	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fkbp4_human(display_long)|uniprotkb:FK506-binding protein 4(gene name synonym)|uniprotkb:HSP-binding immunophilin(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:52 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBP59(gene name synonym)|uniprotkb:Immunophilin FKBP52(gene name synonym)|uniprotkb:FKBP4(gene name)|psi-mi:FKBP4(display_short)|uniprotkb:FKBP52(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:59 kDa immunophilin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002005.1|go:"GO:0070062"(extracellular exosome)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR031212|mint:Q02790|rcsb pdb:1N1A|rcsb pdb:1P5Q|rcsb pdb:1Q1C|rcsb pdb:1QZ2|rcsb pdb:4DRJ|rcsb pdb:4LAV|rcsb pdb:4LAW|rcsb pdb:4LAX|rcsb pdb:4LAY|rcsb pdb:4TW8|go:"GO:0032991"(protein-containing complex)|rcsb pdb:6RCY|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061077"(chaperone-mediated protein folding)|ensembl:ENST00000001008(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|ensembl:ENSG00000004478(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0006825"(copper ion transport)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0032767"(copper-dependent protein binding)|dip:DIP-50866N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:N0vDRDgcQ2x8xiWKdX9Zt+cHcsQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q01105	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q00688	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1044081|uniprotkb:Q14317|ensembl:ENSP00000216330|ensembl:ENSP00000379374|uniprotkb:B2R4Q9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fkbp3_human(display_long)|uniprotkb:FKBP3(gene name)|psi-mi:FKBP3(display_short)|uniprotkb:FKBP25(gene name synonym)|uniprotkb:FK506-binding protein 3(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP25(gene name synonym)|uniprotkb:Rapamycin-selective 25 kDa immunophilin(gene name synonym)|uniprotkb:25 kDa FK506-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002004.1|ensembl:ENSG00000100442(gene)|ensembl:ENST00000216330(transcript)|ensembl:ENST00000396062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR041200|interpro:IPR043368|mint:Q00688|rcsb pdb:1PBK|rcsb pdb:2KFV|rcsb pdb:2MPH|rcsb pdb:5D75|rcsb pdb:5GPG|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:xU5FDlTZzy8veAtOaoLtQMeBsr09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q00325	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325	-	-	crc64:78714C85931B22D5	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P68371	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P68036	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-711173|uniprotkb:P51966|uniprotkb:P70653|uniprotkb:Q9HAV1|ensembl:ENSP00000344259|uniprotkb:B2R4A7|uniprotkb:B4DDG1|uniprotkb:B4DSZ4|uniprotkb:E7EWS7	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2l3_human(display_long)|uniprotkb:Ubiquitin-protein ligase L3(gene name synonym)|uniprotkb:Ubiquitin carrier protein L3(gene name synonym)|uniprotkb:UbcH7(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-F1(gene name synonym)|uniprotkb:L-UBC(gene name synonym)|uniprotkb:UBE2L3(gene name)|psi-mi:UBE2L3(display_short)|uniprotkb:UBCE7(gene name synonym)|uniprotkb:UBCH7(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme L3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003338.1|ensembl:ENSG00000185651(gene)|ensembl:ENST00000342192(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044770"(cell cycle phase transition)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1C4Z|rcsb pdb:1FBV|rcsb pdb:3SQV|rcsb pdb:3SY2|rcsb pdb:4Q5E|rcsb pdb:4Q5H|rcsb pdb:5HPT|rcsb pdb:5TTE|rcsb pdb:5UDH|rcsb pdb:6CP2|rcsb pdb:6DJW|rcsb pdb:6DJX|rcsb pdb:6N13|rcsb pdb:6XXU|rcsb pdb:7B5L|rcsb pdb:7B5N|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|refseq:NP_001243284.1|refseq:NP_001243285.1|dip:DIP-6124N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Axu5Wl2I4nl2wCfMQqYGRBKP6P49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P63313	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2688673|uniprotkb:Q596K9|uniprotkb:P13472|ensembl:ENSP00000233143	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tyb10_human(display_long)|uniprotkb:PTMB10(gene name synonym)|uniprotkb:THYB10(gene name synonym)|uniprotkb:TMSB10(gene name)|psi-mi:TMSB10(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_066926.1|ensembl:ENSG00000034510(gene)|ensembl:ENST00000233143(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0042989"(sequestering of actin monomers)|interpro:IPR001152(Thymosin beta-4)|interpro:IPR038386	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:oyHgjBTa5Wd0RSnF3dTUPsgPV9w9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P63167	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P62837	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347677|uniprotkb:P51669|uniprotkb:Q3MN78|uniprotkb:D3DQC9|uniprotkb:Q96RP6|ensembl:ENSP00000381717|ensembl:ENSP00000381718	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2d2_human(display_long)|uniprotkb:UBC5B(gene name synonym)|uniprotkb:UBCH4(gene name synonym)|uniprotkb:UBE2D2(gene name)|psi-mi:UBE2D2(display_short)|uniprotkb:UBC4(gene name synonym)|uniprotkb:UBCH5B(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D2(gene name synonym)|uniprotkb:Ubiquitin carrier protein D2(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 2(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 2"(gene name synonym)|uniprotkb:PUBC1(gene name synonym)|uniprotkb:p53-regulated ubiquitin-conjugating enzyme 1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D2"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003330.1|refseq:NP_862821.1|dip:DIP-29267N|ensembl:ENSG00000131508(gene)|ensembl:ENST00000398733(transcript)|ensembl:ENST00000398734(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P62837|rcsb pdb:1UR6|rcsb pdb:1W4U|rcsb pdb:2CLW|rcsb pdb:2ESK|rcsb pdb:2ESO|rcsb pdb:2ESP|rcsb pdb:2ESQ|rcsb pdb:3A33|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:3L1Y|rcsb pdb:3TGD|rcsb pdb:3ZNI|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4AUQ|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4LDT|rcsb pdb:4V3K|rcsb pdb:4V3L|rcsb pdb:4WZ3|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5D1K|rcsb pdb:5D1L|rcsb pdb:5D1M|rcsb pdb:5EDV|rcsb pdb:5MNJ|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5VZW|rcsb pdb:5ZBU|rcsb pdb:6HPR|rcsb pdb:6M2C|rcsb pdb:6SQO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6TTU|rcsb pdb:6W7Z|rcsb pdb:6W9D|rcsb pdb:7AI0|rcsb pdb:7AI1|rcsb pdb:7BOL|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-5607764|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:vVGrEi0osU/WG0Y9qRCFMT4lgvg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P62310	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P61604	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P61289	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P61088	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052908|uniprotkb:Q16781|uniprotkb:Q53Y81|ensembl:ENSP00000316176	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ube2n_human(display_long)|uniprotkb:Ubiquitin-protein ligase N(gene name synonym)|uniprotkb:Ubiquitin carrier protein N(gene name synonym)|uniprotkb:Ubc13(gene name synonym)|uniprotkb:Bendless-like ubiquitin-conjugating enzyme(gene name synonym)|uniprotkb:UBE2N(gene name)|psi-mi:UBE2N(display_short)|uniprotkb:BLU(gene name synonym)|uniprotkb:UbcH13(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme N(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003339.1|dip:DIP-29829N|ensembl:ENSG00000177889(gene)|ensembl:ENST00000318066(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031058"(positive regulation of histone modification)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0035370"(UBC13-UEV1A complex)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:1J7D|rcsb pdb:2C2V|rcsb pdb:3HCT|rcsb pdb:3HCU|rcsb pdb:3VON|rcsb pdb:3W31|rcsb pdb:4DHI|rcsb pdb:4DHJ|rcsb pdb:4DHZ|rcsb pdb:4IP3|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:4TKP|rcsb pdb:4WHV|rcsb pdb:5AIT|rcsb pdb:5AIU|rcsb pdb:5EYA|rcsb pdb:5H7S|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5YWR|rcsb pdb:6D6I|rcsb pdb:6JKY|rcsb pdb:6KFP|rcsb pdb:6KG6|rcsb pdb:6KL4|rcsb pdb:6LP2|rcsb pdb:6P5B|rcsb pdb:6S53|reactome:R-HSA-168927|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5607764|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-9646399|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-983168|rcsb pdb:6ULH|rcsb pdb:6UMP|rcsb pdb:6UMS|rcsb pdb:7BBD|rcsb pdb:7BBF|rcsb pdb:7BXG|reactome:R-HSA-1169408|reactome:R-HSA-168638	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:dqdszHlq5FLPHC6UWX6uvkC6Yz89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P61077	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-348268|ensembl:ENSP00000318494|ensembl:ENSP00000337208|ensembl:ENSP00000378283|ensembl:ENSP00000396901|ensembl:ENSP00000344069|ensembl:ENSP00000378280|ensembl:ENSP00000378282|uniprotkb:A6NM99|intact:EBI-2809412|uniprotkb:P47986|uniprotkb:Q6IB88|uniprotkb:Q6NXS4|uniprotkb:Q8N924|uniprotkb:A6NJ93|uniprotkb:A6NJB1	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2d3_human(display_long)|uniprotkb:UBC5C(gene name synonym)|uniprotkb:Ubiquitin-protein ligase D3(gene name synonym)|uniprotkb:Ubiquitin carrier protein D3(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 3(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 3"(gene name synonym)|uniprotkb:UBE2D3(gene name)|psi-mi:UBE2D3(display_short)|uniprotkb:UBCH5C(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D3"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000109332(gene)|ensembl:ENST00000321805(transcript)|ensembl:ENST00000338145(transcript)|ensembl:ENST00000349311(transcript)|ensembl:ENST00000394801(transcript)|ensembl:ENST00000394803(transcript)|ensembl:ENST00000394804(transcript)|ensembl:ENST00000453744(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006915"(apoptotic process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071288"(cellular response to mercury ion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2FUH|rcsb pdb:3L1Z|rcsb pdb:3RPG|rcsb pdb:3UGB|rcsb pdb:4BVU|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:5EGG|rcsb pdb:5IFR|rcsb pdb:6CP0|rcsb pdb:6T7F|rcsb pdb:7JZV|reactome:R-HSA-1234176|reactome:R-HSA-168927|reactome:R-HSA-201451|reactome:R-HSA-2173795|reactome:R-HSA-8866654|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:1X23|refseq:NP_003331.1|refseq:NP_871615.1|refseq:NP_871616.1|refseq:NP_871617.1|refseq:NP_871618.1|refseq:NP_871619.1|refseq:NP_871620.1|refseq:NP_871621.1|refseq:NP_871622.1|dip:DIP-29062N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:jSQ4I+Cgli7HaN5S0OLUP+J5YXs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P61011	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2854176|uniprotkb:B2R759|uniprotkb:P13624|uniprotkb:B4DUW6|ensembl:ENSP00000216774|ensembl:ENSP00000451818|ensembl:ENSP00000504518|ensembl:ENSP00000504673	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:srp54_human(display_long)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:XP_011535408.1|refseq:NP_001139754.1|refseq:NP_003127.1|ensembl:ENSG00000100883(gene)|ensembl:ENST00000678963(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019003"(GDP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036225|interpro:IPR036891|interpro:IPR042101|mint:P61011|rcsb pdb:1MFQ|rcsb pdb:1QB2|rcsb pdb:5L3Q|rcsb pdb:6Y2Z|rcsb pdb:6Y30|rcsb pdb:6Y31|rcsb pdb:6Y32|rcsb pdb:7NFX|ensembl:ENST00000216774(transcript)|reactome:R-HSA-1799339|ensembl:ENST00000556994(transcript)|ensembl:ENST00000677647(transcript)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8iRlU+NvhLEJNv7B90TAZyRqwiY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P60842	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P60604	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051028|uniprotkb:P56554|uniprotkb:A8K3L4|uniprotkb:D3DSL7|uniprotkb:A6NMQ7|ensembl:ENSP00000338348	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2g2_human(display_long)|uniprotkb:Ubiquitin-protein ligase G2(gene name synonym)|uniprotkb:Ubiquitin carrier protein G2(gene name synonym)|uniprotkb:UBE2G2(gene name)|psi-mi:UBE2G2(display_short)|uniprotkb:E2 ubiquitin-conjugating enzyme G2(gene name synonym)|uniprotkb:UBC7(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001189418.1|refseq:NP_003334.2|refseq:NP_872630.1|refseq:XP_016883958.1|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042802"(identical protein binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1904153"(negative regulation of retrograde protein transport, ER to cytosol)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|rcsb pdb:2CYX|rcsb pdb:2KLY|rcsb pdb:2LXP|rcsb pdb:3H8K|rcsb pdb:4LAD|reactome:R-HSA-8866652|reactome:R-HSA-983168|ensembl:ENSG00000184787(gene)|ensembl:ENST00000345496(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-50750N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Q/uslqX/WH/SxKEPYeMmU9CjTBI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P60468	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P58546	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051736|ensembl:ENSP00000376800	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mtpn_human(display_long)|uniprotkb:Protein V-1(gene name synonym)|uniprotkb:MTPN(gene name)|psi-mi:MTPN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_665807.1|ensembl:ENSG00000105887(gene)|ensembl:ENST00000393085(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010557"(positive regulation of macromolecule biosynthetic process)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000812"(regulation of barbed-end actin filament capping)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P58546|rcsb pdb:3AAA|rcsb pdb:7DF7|rcsb pdb:7DSA|rcsb pdb:7DSB|dip:DIP-50234N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:kdJ8vNN4yI2ye49iYUNAtH538b49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P56537	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-372243|uniprotkb:Q6IBN8|uniprotkb:Q96TD5|uniprotkb:B7ZBG9|ensembl:ENSP00000363559|ensembl:ENSP00000363574|ensembl:ENSP00000502429	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:if6_human(display_long)|uniprotkb:EIF6(gene name)|psi-mi:EIF6(display_short)|uniprotkb:ITGB4BP(gene name synonym)|uniprotkb:OK/SW-cl.27(orf name)|uniprotkb:B4 integrin interactor(gene name synonym)|uniprotkb:CAB(gene name synonym)|uniprotkb:"p27(BBP)"(gene name synonym)|uniprotkb:"B(2)GCN homolog"(gene name synonym)|uniprotkb:EIF3A(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002203.1|refseq:NP_852131.1|refseq:NP_852133.1|refseq:NP_001254739.1|ensembl:ENSG00000242372(gene)|ensembl:ENST00000374436(transcript)|ensembl:ENST00000374450(transcript)|ensembl:ENST00000675032(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0032868"(response to insulin)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR002769(Translation initiation factor IF6)|mint:P56537|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:A0pOylQptNBlSiBKiZre7INejF49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P55060	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P54819	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1056291|uniprotkb:Q16856|uniprotkb:Q5TIF7|uniprotkb:Q8TCY2|uniprotkb:Q8TCY3|uniprotkb:A8K6L1|uniprotkb:B4DHH7|uniprotkb:B4DL64|uniprotkb:Q5EB54|ensembl:ENSP00000499935	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:kad2_human(display_long)|uniprotkb:AK2(gene name)|psi-mi:AK2(display_short)|uniprotkb:ADK2(gene name synonym)|uniprotkb:ATP-AMP transphosphorylase 2(gene name synonym)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001186128.1|refseq:NP_001616.1|refseq:NP_037543.1|refseq:NP_001306068.1|refseq:NP_001306069.1|ensembl:ENSG00000004455(gene)|ensembl:ENST00000672715(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097226"(sperm mitochondrial sheath)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028587|interpro:IPR033690|mint:P54819|rcsb pdb:2C9Y|reactome:R-HSA-499943	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pzIKBBzoytYPw3r87WMBueRNpWw9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P53985	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|uniprotkb:Q49A45|ensembl:ENSP00000416167|ensembl:ENSP00000441065|ensembl:ENSP00000485688|ensembl:ENSP00000358640|ensembl:ENSP00000397106|ensembl:ENSP00000399104|ensembl:ENSP00000486000|ensembl:ENSP00000505879	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|ensembl:ENSG00000155380(gene)|ensembl:ENSG00000281917(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032094"(response to food)|ensembl:ENST00000369626(transcript)|ensembl:ENST00000429288(transcript)|ensembl:ENST00000443580(transcript)|ensembl:ENST00000458229(transcript)|ensembl:ENST00000538576(transcript)|ensembl:ENST00000628110(transcript)|ensembl:ENST00000630362(transcript)|ensembl:ENST00000679803(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015130"(mevalonate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0015728"(mevalonate transport)|go:"GO:0016020"(membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051780"(behavioral response to nutrient)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030757|interpro:IPR036259|mint:P53985|go:"GO:1905039"(carboxylic acid transmembrane transport)|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P53621	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P53618	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P53396	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4E3P0|uniprotkb:B4DIM0|ensembl:ENSP00000253792|ensembl:ENSP00000466259	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001087.2|refseq:NP_942127.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|ensembl:ENSG00000131473(gene)|ensembl:ENST00000352035(transcript)|ensembl:ENST00000590151(transcript)|go:"GO:0003878"(ATP citrate synthase activity)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0005524"(ATP binding)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR033847|rcsb pdb:6O0H|interpro:IPR036291|rcsb pdb:6POE|interpro:IPR036969|rcsb pdb:6POF|rcsb pdb:6QFB|mint:P53396|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:3MWD|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|reactome:R-HSA-163765|rcsb pdb:3MWE|reactome:R-HSA-6798695|reactome:R-HSA-75105|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P53007	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005975.1|ensembl:ENSG00000100075(gene)|ensembl:ENST00000215882(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006843"(mitochondrial citrate transmembrane transport)|go:"GO:0015137"(citrate transmembrane transporter activity)|go:"GO:0015142"(tricarboxylic acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071913"(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:P53007|reactome:R-HSA-70263|reactome:R-HSA-75105	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51965	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-348546|uniprotkb:B2RBX4|ensembl:ENSP00000303709|uniprotkb:C9J8K2|uniprotkb:K4DI90	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2e1_human(display_long)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003332.1|refseq:NP_872607.1|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|go:"GO:0070936"(protein K48-linked ubiquitination)|interpro:IPR023313|rcsb pdb:1XR9|rcsb pdb:3BZH|rcsb pdb:4JJQ|rcsb pdb:5LBN|rcsb pdb:6FGA|reactome:R-HSA-1169408|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENST00000306627(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|ensembl:ENSG00000170142(gene)|refseq:NP_001189405.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pPIqYniSQn5Jh7u5x0Lm2NXppQU9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51858	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-3910118|uniprotkb:Q5SZ09|uniprotkb:D3DVC9|uniprotkb:Q5SZ07|uniprotkb:B3KU21|uniprotkb:Q5SZ08|ensembl:ENSP00000349878|ensembl:ENSP00000443120	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hdgf_human(display_long)|uniprotkb:HDGF(gene name)|psi-mi:HDGF(display_short)|uniprotkb:HMG1L2(gene name synonym)|uniprotkb:High mobility group protein 1-like 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001119522.1|refseq:NP_001119523.1|refseq:NP_004485.1|refseq:NP_001306115.1|refseq:NP_001306116.1|refseq:NP_001306117.1|ensembl:ENSG00000143321(gene)|ensembl:ENST00000357325(transcript)|ensembl:ENST00000537739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000313(PWWP)|interpro:IPR035496|mint:P51858|rcsb pdb:1RI0|rcsb pdb:2NLU|reactome:R-HSA-381038	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:72uY+spcb4la5tJDUhHHtOn/Zrs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51668	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-743540|ensembl:ENSP00000363019|uniprotkb:A6NLF6|uniprotkb:A8K786	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ub2d1_human(display_long)|uniprotkb:Ubiquitin-protein ligase D1(gene name synonym)|uniprotkb:Ubiquitin carrier protein D1(gene name synonym)|uniprotkb:UbcH5(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2-17 kDa 1(gene name synonym)|uniprotkb:"Ubiquitin-conjugating enzyme E2(17)KB 1"(gene name synonym)|uniprotkb:UBC4/5 homolog(gene name synonym)|uniprotkb:Stimulator of Fe transport(gene name synonym)|uniprotkb:UBE2D1(gene name)|psi-mi:UBE2D1(display_short)|uniprotkb:UBCH5(gene name synonym)|uniprotkb:UBCH5A(gene name synonym)|uniprotkb:SFT(gene name synonym)|uniprotkb:UBC5A(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme D1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme D1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000072401(gene)|ensembl:ENST00000373910(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|refseq:NP_003329.1|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P51668|rcsb pdb:2C4P|rcsb pdb:2YHO|rcsb pdb:3OJ4|rcsb pdb:3PTF|rcsb pdb:4AP4|rcsb pdb:4QPL|rcsb pdb:5FER|rcsb pdb:5TUT|rcsb pdb:6D4P|reactome:R-HSA-1234176|reactome:R-HSA-141430|reactome:R-HSA-168927|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-201451|reactome:R-HSA-202424|reactome:R-HSA-2173795|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-8866654|reactome:R-HSA-2871837|reactome:R-HSA-8951664|reactome:R-HSA-9033241|reactome:R-HSA-936440|reactome:R-HSA-937041|reactome:R-HSA-9687136|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-5607764|reactome:R-HSA-5689896|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-8866652|dip:DIP-44088N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5BHbufBexJFsiV5kEhqOvdTfvio9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51572	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-77683|ensembl:ENSP00000343458|ensembl:ENSP00000494052|ensembl:ENSP00000499882|uniprotkb:Q13836|uniprotkb:Q96CF0|uniprotkb:D3DWV5|uniprotkb:B3KQ79	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:bap31_human(display_long)|uniprotkb:BCAP31(gene name)|psi-mi:BCAP31(display_short)|uniprotkb:BAP31(gene name synonym)|uniprotkb:p28(gene name synonym)|uniprotkb:6C6-AG tumor-associated antigen(gene name synonym)|uniprotkb:DXS1357E(gene name synonym)|uniprotkb:Protein CDM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001132913.1|refseq:NP_005736.3|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1904154"(positive regulation of retrograde protein transport, ER to cytosol)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR008417(B-cell receptor-associated 31-like)|interpro:IPR040463|interpro:IPR041672|mint:P51572|rcsb pdb:4JZL|rcsb pdb:4JZP|reactome:R-HSA-111465|reactome:R-HSA-75153|reactome:R-HSA-8980692|reactome:R-HSA-983170|ensembl:ENSG00000185825(gene)|ensembl:ENST00000345046(transcript)|ensembl:ENST00000647529(transcript)|ensembl:ENST00000672675(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044877"(protein-containing complex binding)|refseq:NP_001243376.1|refseq:NP_001132929.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:m0aN00PLZJDWA/K1vEbla1W9+S89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51571	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1054539|uniprotkb:Q53XY1|uniprotkb:A8K378|ensembl:ENSP00000317331|ensembl:ENSP00000359103|ensembl:ENSP00000359104	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ssrd_human(display_long)|uniprotkb:Signal sequence receptor subunit delta(gene name synonym)|uniprotkb:SSR4(gene name)|psi-mi:SSR4(display_short)|uniprotkb:TRAPD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001191455.1|refseq:NP_006271.1|refseq:XP_011529488.1|refseq:XP_011529489.1|ensembl:ENSG00000180879(gene)|ensembl:ENST00000320857(transcript)|ensembl:ENST00000370086(transcript)|ensembl:ENST00000370087(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008855(Translocon-associated)|mint:P51571|reactome:R-HSA-1799339	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:2SNgZQH/jwi61UcuHUf7RYKZH589606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P49915	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1050289|uniprotkb:A8K639|uniprotkb:B4DXV7|uniprotkb:F8W720|ensembl:ENSP00000419851	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:guaa_human(display_long)|uniprotkb:GMP synthetase(gene name synonym)|uniprotkb:Glutamine amidotransferase(gene name synonym)|uniprotkb:GMPS(gene name)|psi-mi:GMPS(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003866.1|ensembl:ENSG00000163655(gene)|ensembl:ENST00000496455(transcript)|go:"GO:0003921"(GMP synthase activity)|go:"GO:0003922"("GMP synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0016462"(pyrophosphatase activity)|interpro:IPR001674(GMP synthase, C-terminal)|interpro:IPR004739(GMP synthase, N-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017926|interpro:IPR022310|interpro:IPR025777|interpro:IPR029062|mint:P49915|rcsb pdb:2VPI|rcsb pdb:2VXO|reactome:R-HSA-73817	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:LYs65bPoqjVG/ZxA6v+yJo3HsLI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P49755	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-998422|uniprotkb:Q15602|uniprotkb:Q16536|uniprotkb:Q86TC2|uniprotkb:Q86TS5|uniprotkb:B2R605|intact:EBI-1058680|ensembl:ENSP00000303145	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tmeda_human(display_long)|uniprotkb:21 kDa transmembrane-trafficking protein(gene name synonym)|uniprotkb:Transmembrane protein Tmp21(gene name synonym)|uniprotkb:Tmp-21-I(gene name synonym)|uniprotkb:p24delta(gene name synonym)|uniprotkb:S31III125(gene name synonym)|uniprotkb:TMED10(gene name)|psi-mi:TMED10(display_short)|uniprotkb:TMP21(gene name synonym)|uniprotkb:p23(gene name synonym)|uniprotkb:p24 family protein delta-1(gene name synonym)|uniprotkb:S31I125(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0007030"(Golgi organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0035964"(COPI-coated vesicle budding)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048199"(vesicle targeting, to, from or within Golgi)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0070765"(gamma-secretase complex)|go:"GO:0106272"(protein localization to ERGIC)|go:"GO:0106273"(cytosol to ERGIC protein transport)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:P49755|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811434|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|ensembl:ENSG00000170348(gene)|ensembl:ENST00000303575(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001822"(kidney development)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|refseq:NP_006818.3	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Sj4B0x1qf0VJmI1aDFaw2/PiTxM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P49588	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-709710|uniprotkb:A6NF14|uniprotkb:Q53GV7|uniprotkb:Q96FA0|uniprotkb:B4DR45|ensembl:ENSP00000261772|ensembl:ENSP00000501924|ensembl:ENSP00000502247|ensembl:ENSP00000502797	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:syac_human(display_long)|uniprotkb:AARS1(gene name)|psi-mi:AARS1(display_short)|uniprotkb:AARS(gene name synonym)|uniprotkb:Alanyl-tRNA synthetase(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-42(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001596.2|ensembl:ENSG00000090861(gene)|ensembl:ENST00000261772(transcript)|ensembl:ENST00000674691(transcript)|ensembl:ENST00000674963(transcript)|ensembl:ENST00000675643(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0002196"("Ser-tRNA(Ala) hydrolase activity")|go:"GO:0004813"(alanine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006419"(alanyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016597"(amino acid binding)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045182"(translation regulator activity)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140018"(regulation of cytoplasmic translational fidelity)|interpro:IPR002318(Alanyl-tRNA synthetase, class IIc)|interpro:IPR003156(Phosphoesterase, DHHA1)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018162|interpro:IPR018163|interpro:IPR018164|interpro:IPR018165|interpro:IPR023033|mint:P49588|rcsb pdb:4XEM|rcsb pdb:4XEO|rcsb pdb:5KNN|rcsb pdb:5T5S|rcsb pdb:5T76|rcsb pdb:5V59|reactome:R-HSA-379716	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:e9+gLroLXvK8li0wiPBGbZhQqP49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P49411	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359097|uniprotkb:O15276|ensembl:ENSP00000322439	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:eftu_human(display_long)|uniprotkb:TUFM(gene name)|psi-mi:TUFM(display_short)|uniprotkb:P43(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003312.3|ensembl:ENSG00000178952(gene)|ensembl:ENST00000313511(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0016020"(membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P49411|rcsb pdb:7A5G|rcsb pdb:7O9K|reactome:R-HSA-5389840|refseq:XP_016879108.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pDRPUBUqvFqnh613N8bDTl4sFHc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P49327	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P49321	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-716205|uniprotkb:Q53GW5|uniprotkb:Q5T625|uniprotkb:Q5T622|uniprotkb:Q96A69|uniprotkb:Q9BTW2|uniprotkb:A8K6H2|uniprotkb:B4DQP3|uniprotkb:F5H3J2|uniprotkb:D3DQ07|intact:EBI-28989159|ensembl:ENSP00000255120	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:nasp_human(display_long)|uniprotkb:NASP(gene name)|psi-mi:NASP(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001182122.1|refseq:NP_002473.2|refseq:NP_689511.2|ensembl:ENSG00000132780(gene)|ensembl:ENST00000350030(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0008584"(male gonad development)|go:"GO:0015031"(protein transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019544|interpro:IPR019734|mint:P49321|ensembl:ENSP00000255120|ensembl:ENST00000351223|ensembl:ENSP00000255121|ensembl:ENST00000537798|ensembl:ENSP00000438871|refseq:XP_005270945.1|dip:DIP-47269N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8BOknyp+vOh6NF+fXZPYbbqFbH49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P49006	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-4289961|uniprotkb:Q5TEE6|uniprotkb:Q6NXS5|uniprotkb:D3DPQ0|ensembl:ENSP00000362638	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:mrp_human(display_long)|uniprotkb:MARCKSL1(gene name)|psi-mi:MARCKSL1(display_short)|uniprotkb:MLP(gene name synonym)|uniprotkb:MRP(gene name synonym)|uniprotkb:MARCKS-like protein 1(gene name synonym)|uniprotkb:Macrophage myristoylated alanine-rich C kinase substrate(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000175130(gene)|ensembl:ENST00000329421(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P49006|refseq:NP_075385.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:nkq8hGJINvCHlZJ3alKkDP+wCxk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P48507	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051387|uniprotkb:Q6FHC1|uniprotkb:Q9NPX9|uniprotkb:Q9NU74|uniprotkb:A8K334|uniprotkb:M5A959|uniprotkb:D3DT45|ensembl:ENSP00000359258	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:gsh0_human(display_long)|uniprotkb:Gamma-glutamylcysteine synthetase regulatory subunit(gene name synonym)|uniprotkb:Gamma-ECS regulatory subunit(gene name synonym)|uniprotkb:GCS light chain(gene name synonym)|uniprotkb:Glutamate--cysteine ligase modifier subunit(gene name synonym)|uniprotkb:GCLM(gene name)|psi-mi:GCLM(display_short)|uniprotkb:GLCLR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002052.1|refseq:NP_001295182.1|ensembl:ENSG00000023909(gene)|ensembl:ENST00000370238(transcript)|go:"GO:0004357"(glutamate-cysteine ligase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006534"(cysteine metabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0014823"(response to activity)|go:"GO:0017109"(glutamate-cysteine ligase complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0035226"(glutamate-cysteine ligase catalytic subunit binding)|go:"GO:0035229"(positive regulation of glutamate-cysteine ligase activity)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035733"(hepatic stellate cell activation)|go:"GO:0042493"|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044752"(response to human chorionic gonadotropin)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047834"(D-threo-aldose 1-dehydrogenase activity)|go:"GO:0051409"(response to nitrosative stress)|go:"GO:0051900"(regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:0097069"(cellular response to thyroxine stimulus)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR023210|interpro:IPR032963|interpro:IPR036812|reactome:R-HSA-174403|reactome:R-HSA-5578999	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:arU12Xm86K7yRxElliA31V7z5d89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P47897	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347462|uniprotkb:B4DWJ2|ensembl:ENSP00000307567	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:syq_human(display_long)|uniprotkb:QARS1(gene name)|psi-mi:QARS1(display_short)|uniprotkb:Glutaminyl-tRNA synthetase(gene name synonym)|uniprotkb:QARS(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005042.1|ensembl:ENSG00000172053(gene)|ensembl:ENST00000306125(transcript)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000924(Glutamyl/glutaminyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR004514(Glutaminyl-tRNA synthetase, class Ic)|interpro:IPR007638(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 2)|interpro:IPR007639(Glutaminyl-tRNA synthetase, class Ic, non-specific RNA-binding region part 1)|interpro:IPR011035(Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR020056|interpro:IPR020058|interpro:IPR020059|interpro:IPR042558|interpro:IPR042559|mint:P47897|rcsb pdb:4R3Z|rcsb pdb:4YE6|rcsb pdb:4YE8|rcsb pdb:4YE9|reactome:R-HSA-2408522|go:"GO:0006469"(negative regulation of protein kinase activity)|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0007420"(brain development)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_001259002.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:3Q8LR+aWJJue/ixtD3ZYDpC/D3o9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P46379	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347552|uniprotkb:A2ADJ7|uniprotkb:A3KQ42|uniprotkb:A3KQ44|uniprotkb:A6NGY6|uniprotkb:A6PWF7|uniprotkb:O95874|uniprotkb:Q5HYL9|uniprotkb:Q5SQ35|uniprotkb:Q5SQ36|uniprotkb:Q5SQ37|uniprotkb:Q5SQ41|uniprotkb:Q5SRP8|uniprotkb:Q5SRP9|uniprotkb:Q5STC1|uniprotkb:Q5STX1|uniprotkb:Q5STX3|uniprotkb:Q96SA6|uniprotkb:Q9BCN4|uniprotkb:B0UX84|uniprotkb:B4DZ12|uniprotkb:B4E3V4|uniprotkb:E7EMZ4|uniprotkb:F8VXY4|ensembl:ENSP00000354368|ensembl:ENSP00000390966|ensembl:ENSP00000397894	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:bag6_human(display_long)|uniprotkb:BAT3(gene name synonym)|uniprotkb:G3(gene name synonym)|uniprotkb:HLA-B-associated transcript 3(gene name synonym)|uniprotkb:Protein G3(gene name synonym)|uniprotkb:BCL2-associated athanogene 6(gene name synonym)|uniprotkb:BAG6(gene name)|psi-mi:BAG6(display_short)|uniprotkb:BAG family molecular chaperone regulator 6(gene name synonym)|uniprotkb:Protein Scythe(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	dip:DIP-31191N|refseq:NP_001092004.1|refseq:NP_001186627.1|refseq:NP_004630.3|refseq:NP_542433.1|refseq:NP_542434.1|refseq:NP_001186626.1|refseq:XP_016866776.1|ensembl:ENSG00000096155(gene)|ensembl:ENSG00000229524(gene)|ensembl:ENSG00000233348(gene)|ensembl:ENST00000361076(transcript)|ensembl:ENST00000449450(transcript)|ensembl:ENST00000451932(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002429"(immune response-activating cell surface receptor signaling pathway)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0050821"(protein stabilization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070628"(proteasome binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0071818"(BAT3 complex)|go:"GO:1904294"(positive regulation of ERAD pathway)|go:"GO:1904378"(maintenance of unfolded protein involved in ERAD pathway)|go:"GO:1904379"(protein localization to cytosolic proteasome complex involved in ERAD pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR021925|interpro:IPR029071|mint:P46379|rcsb pdb:1WX9|rcsb pdb:2N9P|rcsb pdb:4DWF|rcsb pdb:4EEW|rcsb pdb:4WWR|rcsb pdb:6AU8|reactome:R-HSA-9609523|rcsb pdb:4X86	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:ghHlLBbS3yeP2mN6AOoHs+CECKU9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P46109	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P46060	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P45880	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-354022|ensembl:ENSP00000361686|ensembl:ENSP00000443092|uniprotkb:Q5VWK1|uniprotkb:Q5VWK3|uniprotkb:Q6IB40|uniprotkb:Q7L3J5|uniprotkb:Q9BWK8|uniprotkb:Q9Y5I6	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:vdac2_human(display_long)|uniprotkb:VDAC2(gene name)|psi-mi:VDAC2(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000165637(gene)|ensembl:ENST00000332211(transcript)|ensembl:ENST00000543351(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|refseq:NP_001171712.1|refseq:NP_001171752.1|refseq:NP_003366.2|refseq:NP_001311017.1|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P45880|reactome:R-HSA-5689880|reactome:R-HSA-8949215	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:seQxCd19Z2HmpXcwb48osAuuafA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P43487	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1032909|uniprotkb:Q53EY3|ensembl:ENSP00000327583	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rang_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002873.1|ensembl:ENSG00000099901(gene)|ensembl:ENST00000331821(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1K5D|rcsb pdb:1K5G|reactome:R-HSA-165054|refseq:NP_001265568.1|refseq:NP_001265569.1|dip:DIP-35058N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:OWndphaUCDSO3+MGhJqcuQo2Lk09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P43246	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355888|uniprotkb:O75488|uniprotkb:B4E2Z2|ensembl:ENSP00000233146	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:msh2_human(display_long)|uniprotkb:MSH2(gene name)|psi-mi:MSH2(display_short)|uniprotkb:MutS protein homolog 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000242.1|refseq:NP_001245210.1|ensembl:ENSG00000095002(gene)|ensembl:ENST00000233146(transcript)|go:"GO:0000406"(double-strand/single-strand DNA junction binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002204"(somatic recombination of immunoglobulin genes involved in immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006281"(DNA repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0007281"(germ cell development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008584"(male gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0016020"(membrane)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016447"(somatic recombination of immunoglobulin gene segments)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0019724"(B cell mediated immunity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0032137"(guanine/thymine mispair binding)|go:"GO:0032300"(mismatch repair complex)|go:"GO:0032301"(MutSalpha complex)|go:"GO:0032302"(MutSbeta complex)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043570"(maintenance of DNA repeat elements)|go:"GO:0045190"(isotype switching)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0071168"(protein localization to chromatin)|interpro:IPR000432(DNA mismatch repair protein MutS, C-terminal)|interpro:IPR007695(DNA mismatch repair protein MutS-like, N-terminal)|interpro:IPR007696(DNA mismatch repair protein MutS, core)|interpro:IPR007860(DNA mismatch repair protein MutS, connector)|interpro:IPR007861(DNA mismatch repair protein MutS, clamp)|interpro:IPR011184(DNA mismatch repair protein, MSH2)|interpro:IPR016151(DNA mismatch repair protein MutS, N-terminal)|interpro:IPR027417|interpro:IPR032642|interpro:IPR036187|interpro:IPR036678|mint:P43246|rcsb pdb:2O8B|rcsb pdb:2O8C|rcsb pdb:2O8D|rcsb pdb:2O8E|rcsb pdb:2O8F|rcsb pdb:3THW|rcsb pdb:3THX|rcsb pdb:3THY|rcsb pdb:3THZ|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5632927|reactome:R-HSA-5632928|reactome:R-HSA-5632968|reactome:R-HSA-6796648|dip:DIP-35054N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7vcyX6SkXRo28b+4b+JBg7j/ec89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P42771	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-375053|uniprotkb:O95440|uniprotkb:Q15191|uniprotkb:Q5VVJ5|uniprotkb:Q96B52|uniprotkb:Q9NP05|uniprotkb:A5X2G7|ensembl:ENSP00000307101|uniprotkb:D3DRK1|intact:EBI-7576126|intact:MINT-1344330|uniprotkb:G3XAG3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cdn2a_human(display_long)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:Cyclin-dependent kinase 4 inhibitor A(gene name synonym)|uniprotkb:p16-INK4a(gene name synonym)|uniprotkb:Multiple tumor suppressor 1(gene name synonym)|uniprotkb:MTS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000068.1|refseq:NP_478104.2|refseq:XP_011515981.1|ensembl:ENSG00000147889(gene)|ensembl:ENST00000304494(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003723"(RNA binding)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR036770|mint:P42771|rcsb pdb:1A5E|rcsb pdb:1BI7|rcsb pdb:1DC2|rcsb pdb:2A5E|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231|reactome:R-HSA-8853884|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|refseq:NP_001182061.1|refseq:XP_005251400.1|dip:DIP-6108N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:9qd+YTVorW7jBQB23jJuOuMUKCk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P41250	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-724143|uniprotkb:B3KQA2|uniprotkb:B4DIA0|ensembl:ENSP00000373918|uniprotkb:Q969Y1|intact:EBI-25629666|uniprotkb:A0A090N8G0	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:gars_human(display_long)|uniprotkb:GARS1(gene name)|psi-mi:GARS1(display_short)|uniprotkb:Diadenosine tetraphosphate synthetase(gene name synonym)|uniprotkb:GARS(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002038.2|rcsb pdb:4KQE|rcsb pdb:4KR2|rcsb pdb:2ZT6|rcsb pdb:4KR3|rcsb pdb:4QEI|rcsb pdb:5E6M|reactome:R-HSA-379716|rcsb pdb:2ZT7|reactome:R-HSA-379726|rcsb pdb:2ZT8|rcsb pdb:2ZXF|ensembl:ENSG00000106105(gene)|ensembl:ENST00000389266(transcript)|go:"GO:0004081"("bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity")|go:"GO:0004820"(glycine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006426"(glycyl-tRNA aminoacylation)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016740"(transferase activity)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070150"(mitochondrial glycyl-tRNA aminoacylation)|interpro:IPR000738(WHEP-TRS)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002315(Glycyl-tRNA synthetase, alpha2 dimer)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR027031|interpro:IPR033731|interpro:IPR036621|mint:P41250|rcsb pdb:2PME|rcsb pdb:2PMF|rcsb pdb:2Q5H|rcsb pdb:2Q5I|rcsb pdb:2ZT5|refseq:NP_001303701.1|dip:DIP-50471N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:bBlAPOMGXKsEvu0DxGKJJLjDI1s9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P40222	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359793|uniprotkb:Q5TFJ6|uniprotkb:Q66K62|uniprotkb:Q86T54|uniprotkb:Q86T85|uniprotkb:Q86T86|uniprotkb:Q86Y86|uniprotkb:Q86YW3|uniprotkb:Q8N2Y3|uniprotkb:D3DPP6|ensembl:ENSP00000362711|ensembl:ENSP00000362712	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:txlna_human(display_long)|uniprotkb:TXLNA(gene name)|psi-mi:TXLNA(display_short)|uniprotkb:TXLN(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_787048.1|ensembl:ENSG00000084652(gene)|ensembl:ENST00000373609(transcript)|ensembl:ENST00000373610(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0016020"(membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0042113"(B cell activation)|interpro:IPR026183|reactome:R-HSA-449836|refseq:XP_016856051.1|dip:DIP-27612N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:m6McBNTQ5VY4RNUY6PyYTj97YUk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P39748	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-707816|ensembl:ENSP00000305480	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fen1_human(display_long)|uniprotkb:Flap structure-specific endonuclease 1(gene name synonym)|uniprotkb:Maturation factor 1(gene name synonym)|uniprotkb:DNase IV(gene name synonym)|uniprotkb:FEN1(gene name)|psi-mi:FEN1(display_short)|uniprotkb:RAD2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000168496(gene)|ensembl:ENST00000305885(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|refseq:NP_004102.1|dip:DIP-24216N|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007613"(memory)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0009650"(UV protection)|go:"GO:0016020"(membrane)|go:"GO:0017108"(5'-flap endonuclease activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032201"(telomere maintenance via semi-conservative replication)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0048256"(flap endonuclease activity)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|interpro:IPR006084("DNA repair protein (XPGC)/yeast Rad")|interpro:IPR006085(XPG N-terminal)|interpro:IPR006086(XPG I)|interpro:IPR008918(Helix-hairpin-helix motif, class 2)|interpro:IPR019974|interpro:IPR023426|interpro:IPR029060|interpro:IPR036279|mint:P39748|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:3Q8K|rcsb pdb:3Q8L|rcsb pdb:3Q8M|rcsb pdb:3UVU|rcsb pdb:5E0V|rcsb pdb:5FV7|rcsb pdb:5K97|rcsb pdb:5KSE|rcsb pdb:5UM9|rcsb pdb:5ZOD|rcsb pdb:5ZOE|rcsb pdb:5ZOF|rcsb pdb:5ZOG|rcsb pdb:6TNZ|reactome:R-HSA-110362|reactome:R-HSA-162594|reactome:R-HSA-174437|reactome:R-HSA-5651801|reactome:R-HSA-5685939|reactome:R-HSA-69166	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:l9A+/Q39cGBPac0d8USNWE+17NM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P39687	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P38646	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-354932|ensembl:ENSP00000297185|uniprotkb:P30036|uniprotkb:P31932|uniprotkb:Q6GU03|uniprotkb:Q9BWB7|uniprotkb:B2RCM1|uniprotkb:Q1HB43|uniprotkb:Q53H23|uniprotkb:Q9UC56	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:grp75_human(display_long)|uniprotkb:HSPA9(gene name)|psi-mi:HSPA9(display_short)|uniprotkb:GRP75(gene name synonym)|uniprotkb:HSPA9B(gene name synonym)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:mt-HSP70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	reactome:R-HSA-8949613|reactome:R-HSA-8950505|ensembl:ENSG00000113013(gene)|ensembl:ENST00000297185(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005925"(focal adhesion)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0140275"(MIB complex)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|go:"GO:0070062"(extracellular exosome)|interpro:IPR043129|mint:P38646|rcsb pdb:3N8E|rcsb pdb:4KBO|rcsb pdb:6NHK|rcsb pdb:6P2U|rcsb pdb:6PMT|reactome:R-HSA-1268020|reactome:R-HSA-3371453|refseq:NP_004125.3|dip:DIP-32936N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:xjSHeTKBb/lH1XNEEiMIjsM+XcE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P38606	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1054757|intact:EBI-10982175|uniprotkb:Q53YD9|uniprotkb:Q96DY6|uniprotkb:Q9UHY3|uniprotkb:B2RBR8|uniprotkb:B7Z1R5|uniprotkb:D3DN75|ensembl:ENSP00000273398	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:vata_human(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Vacuolar ATPase isoform VA68(gene name synonym)|uniprotkb:ATP6V1A(gene name)|psi-mi:ATP6V1A(display_short)|uniprotkb:ATP6A1(gene name synonym)|uniprotkb:ATP6V1A1(gene name synonym)|uniprotkb:VPP2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001681.2|ensembl:ENSG00000114573(gene)|ensembl:ENST00000273398(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016469"(proton-transporting two-sector ATPase complex)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:P38606|rcsb pdb:6WLZ|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:GqPRFwsl5tDH83kpE8Al7NiYWrI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P36969	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2510844|uniprotkb:O43381|uniprotkb:Q9UPK2|uniprotkb:Q6PJ59|ensembl:ENSP00000346103	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:gpx4_human(display_long)|uniprotkb:GPX4(gene name)|psi-mi:GPX4(display_short)|uniprotkb:Glutathione peroxidase 4(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002076.2|refseq:NP_001034936.1|dip:DIP-53543N|reactome:R-HSA-9023661|reactome:R-HSA-9020265|ensembl:ENSG00000167468(gene)|ensembl:ENST00000354171(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007568"(aging)|go:"GO:0008430"(selenium binding)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019372"(lipoxygenase pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0047066"(phospholipid-hydroperoxide glutathione peroxidase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051258"(protein polymerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0110076"(negative regulation of ferroptosis)|interpro:IPR000889(Glutathione peroxidase)|interpro:IPR029759|interpro:IPR029760|interpro:IPR036249|rcsb pdb:2GS3|rcsb pdb:2OBI|rcsb pdb:5H5Q|rcsb pdb:5H5R|rcsb pdb:5H5S|rcsb pdb:6ELW|rcsb pdb:6HKQ|rcsb pdb:6HN3|reactome:R-HSA-2142688|reactome:R-HSA-2142712|reactome:R-HSA-2142770|reactome:R-HSA-9018676|reactome:R-HSA-9018896	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:SUjUUl4rV/SKmLkV6WOiM+nusio9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P35613	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P35520	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-740135|uniprotkb:Q99425|uniprotkb:Q9BWC5|uniprotkb:B2R993|uniprotkb:D3DSK4|intact:EBI-14245939|ensembl:ENSP00000344460|ensembl:ENSP00000352643|ensembl:ENSP00000381225|ensembl:ENSP00000381231	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cbs_human(display_long)|uniprotkb:CBS(gene name)|psi-mi:CBS(display_short)|uniprotkb:Serine sulfhydrase(gene name synonym)|uniprotkb:Beta-thionase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000062.1|refseq:NP_001171479.1|refseq:NP_001171480.1|ensembl:ENSG00000160200(gene)|ensembl:ENST00000352178(transcript)|ensembl:ENST00000359624(transcript)|ensembl:ENST00000398158(transcript)|go:"GO:0004122"(cystathionine beta-synthase activity)|ensembl:ENST00000398165(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006535"(cysteine biosynthetic process from serine)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0019343"(cysteine biosynthetic process via cystathionine)|go:"GO:0019344"(cysteine biosynthetic process)|go:"GO:0019346"(transsulfuration)|go:"GO:0019448"(L-cysteine catabolic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042262"(DNA protection)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050421"("nitrite reductase (NO-forming) activity")|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070025"(carbon monoxide binding)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070814"(hydrogen sulfide biosynthetic process)|go:"GO:0072341"(modified amino acid binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001216(Cysteine synthase/cystathionine beta-synthase P-phosphate-binding site)|interpro:IPR001926(Pyridoxal phosphate-dependent enzyme, beta subunit)|interpro:IPR005857(Cystathionine beta-synthase)|interpro:IPR036052|mint:P35520|rcsb pdb:1JBQ|rcsb pdb:1M54|rcsb pdb:4COO|rcsb pdb:4L0D|rcsb pdb:4L27|rcsb pdb:4L28|rcsb pdb:4L3V|rcsb pdb:4PCU|rcsb pdb:4UUU|rcsb pdb:5MMS|reactome:R-HSA-1614603|reactome:R-HSA-2408508|refseq:XP_011528079.1|refseq:XP_011528083.1|refseq:XP_011528084.1|refseq:XP_011544396.1|refseq:XP_011544397.1|refseq:XP_011544399.1|refseq:XP_011544400.1|refseq:XP_011544401.1|refseq:NP_001307227.1|refseq:NP_001308002.1|refseq:XP_016883700.1|refseq:XP_016883701.1|refseq:XP_016883702.1|refseq:XP_016883703.1|refseq:XP_016883704.1|refseq:XP_016883705.1|refseq:XP_016883706.1|refseq:XP_016883707.1|refseq:XP_016883978.1|refseq:XP_016883979.1|refseq:XP_016883980.1|refseq:XP_016883981.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:f9eo0cPOHppVY7Nqejag3YyK18s9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P35232	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P34932	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P34897	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P32119	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P31948	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006810.1|ensembl:ENSG00000168439(gene)|ensembl:ENST00000305218(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|reactome:R-HSA-3371497|reactome:R-HSA-9696273|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P31947	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P31946-2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10770173	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:p31946-2(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein 1054(gene name synonym)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	intact:EBI-359815(isoform-parent)|uniprotkb:P31946-2(isoform-parent)	-	-	isoform-comment:Contains a N-acetylmethionine at position 1.	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8mvstxtXif8GTzC81FfeGOm12yg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P31939	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1048599|uniprotkb:Q13856|uniprotkb:Q53S28|uniprotkb:A8K202|uniprotkb:E9PBU3|ensembl:ENSP00000236959	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pur9_human(display_long)|uniprotkb:ATIC(gene name)|psi-mi:ATIC(display_short)|uniprotkb:PURH(gene name synonym)|uniprotkb:OK/SW-cl.86(orf name)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004035.2|ensembl:ENSG00000138363(gene)|ensembl:ENST00000236959(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046452"(dihydrofolate metabolic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|rcsb pdb:1P4R|rcsb pdb:1PKX|rcsb pdb:1PL0|rcsb pdb:5UY8|rcsb pdb:5UZ0|reactome:R-HSA-73817	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Xe3388w/LOBYgag9P8Gp3IGo9wU9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P31930	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052596|uniprotkb:Q96DD2|uniprotkb:B2R7R8|ensembl:ENSP00000203407	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:qcr1_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 1(gene name synonym)|uniprotkb:Complex III subunit 1(gene name synonym)|uniprotkb:UQCRC1(gene name)|psi-mi:UQCRC1(display_short)|uniprotkb:Core protein I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003356.2|ensembl:ENSG00000010256(gene)|ensembl:ENST00000203407(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0014823"(response to activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P31930|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7Yrm6OhOmgfHF5mAX3hT3DMGnkc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P31689	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P31040	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1057265|uniprotkb:Q16395|uniprotkb:Q9UMY5|uniprotkb:B4DJ60|uniprotkb:E9PBJ5|uniprotkb:Q59GW8|uniprotkb:Q8IW48|uniprotkb:A8K5J6|ensembl:ENSP00000264932	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sdha_human(display_long)|uniprotkb:SDHA(gene name)|psi-mi:SDHA(display_short)|uniprotkb:SDH2(gene name synonym)|uniprotkb:SDHF(gene name synonym)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001281261.1|refseq:NP_004159.2|ensembl:ENSG00000073578(gene)|ensembl:ENST00000264932(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|rcsb pdb:6VAX|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-45851N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:NfhgIzmcsvfPG1BP7tHcna+jTIY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P30520	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042898|uniprotkb:Q96EG7|ensembl:ENSP00000355493|uniprotkb:B1AQM5	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pura2_human(display_long)|uniprotkb:ADSS2(gene name)|psi-mi:ADSS2(display_short)|uniprotkb:ADSS(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, acidic isozyme(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, liver isozyme(gene name synonym)|uniprotkb:IMP--aspartate ligase 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000035687(gene)|ensembl:ENST00000366535(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002376"(immune system process)|go:"GO:0004019"(adenylosuccinate synthase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0014074"(response to purine-containing compound)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071257"(cellular response to electrical stimulus)|interpro:IPR001114(Adenylosuccinate synthetase)|interpro:IPR018220|interpro:IPR027417|interpro:IPR027529|interpro:IPR033128|interpro:IPR042109|interpro:IPR042110|interpro:IPR042111|mint:P30520|rcsb pdb:2V40|reactome:R-HSA-73817|refseq:NP_001117.2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Tyydt3Z/JHGYtfY9oc9XfFkDguM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P30101	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P30044	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-722161|uniprotkb:Q14CK0|uniprotkb:Q6IAF2|uniprotkb:Q9UBU5|uniprotkb:Q9UJU4|uniprotkb:Q9UKX4|uniprotkb:A6NG06|uniprotkb:B7ZLJ4|uniprotkb:A6NC19|uniprotkb:B7ZVW3|ensembl:ENSP00000265462	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prdx5_human(display_long)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:TPx type VI(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 71B(gene name synonym)|uniprotkb:Alu corepressor 1(gene name synonym)|uniprotkb:PRDX5(gene name)|psi-mi:PRDX5(display_short)|uniprotkb:ACR1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)|uniprotkb:SBBI10(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_036226.1|refseq:NP_857634.1|refseq:NP_857635.1|ensembl:ENSG00000126432(gene)|ensembl:ENST00000265462(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037944|mint:P30044|rcsb pdb:1H4O|rcsb pdb:1HD2|rcsb pdb:1OC3|rcsb pdb:1URM|rcsb pdb:2VL2|rcsb pdb:2VL3|rcsb pdb:2VL9|rcsb pdb:3MNG|rcsb pdb:4K7I|rcsb pdb:4K7N|rcsb pdb:4K7O|rcsb pdb:4MMM|reactome:R-HSA-3299685|reactome:R-HSA-5628897	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Z1fs04RUXWI7z+s7Y+hzGige4mU9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P30041	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2255129|uniprotkb:A8JZY7|uniprotkb:P32077|uniprotkb:Q5TAH4|uniprotkb:Q5ZEZ8|ensembl:ENSP00000342026	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prdx6_human(display_long)|uniprotkb:PRDX6(gene name)|psi-mi:PRDX6(display_short)|uniprotkb:AOP2(gene name synonym)|uniprotkb:KIAA0106(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:24 kDa protein(gene name synonym)|uniprotkb:Liver 2D page spot 40(gene name synonym)|uniprotkb:Red blood cells page spot 12(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004896.1|ensembl:ENSG00000117592(gene)|ensembl:ENST00000340385(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:1PRX|rcsb pdb:5B6M|rcsb pdb:5B6N|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0042744"(hydrogen peroxide catabolic process)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:ZMsHgrAJf0VJiCELzo+zSi8Ji+49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P30040	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-946830|uniprotkb:Q3MJC3|uniprotkb:Q6FHT4|uniprotkb:C9J183|ensembl:ENSP00000261735	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:erp29_human(display_long)|uniprotkb:ERP29(gene name)|psi-mi:ERP29(display_short)|uniprotkb:C12orf8(gene name synonym)|uniprotkb:ERP28(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 31(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 28(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006808.1|refseq:NP_001029197.1|ensembl:ENSG00000089248(gene)|ensembl:ENST00000261735(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0042470"(melanosome)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043335"(protein unfolding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR011679(Endoplasmic reticulum, protein ERp29, C-terminal)|interpro:IPR012883(ERp29, N-terminal)|interpro:IPR016855(Endoplasmic reticulum, protein ERp29)|interpro:IPR036249|interpro:IPR036356|rcsb pdb:2QC7|rcsb pdb:5V8Z|rcsb pdb:5V90	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5+uNyIlUU6txfPlS4DSPunpjz3M9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P29372	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1043398|uniprotkb:Q13770|uniprotkb:Q15275|uniprotkb:Q15961|uniprotkb:Q96BZ6|uniprotkb:Q96S33|uniprotkb:Q9NNX5|ensembl:ENSP00000219431|intact:EBI-10970139|uniprotkb:G5E9E2|uniprotkb:Q5J9I4	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:3mg_human(display_long)|uniprotkb:3-methyladenine DNA glycosidase(gene name synonym)|uniprotkb:ADPG(gene name synonym)|uniprotkb:3-alkyladenine DNA glycosylase(gene name synonym)|uniprotkb:N-methylpurine-DNA glycosylase(gene name synonym)|uniprotkb:MPG(gene name)|psi-mi:MPG(display_short)|uniprotkb:AAG(gene name synonym)|uniprotkb:ANPG(gene name synonym)|uniprotkb:MID1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000103152(gene)|ensembl:ENST00000219431(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003905"(alkylbase DNA N-glycosylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008725"(DNA-3-methyladenine glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043916"(DNA-7-methylguanine glycosylase activity)|go:"GO:0045007"(depurination)|go:"GO:0052821"(DNA-7-methyladenine glycosylase activity)|go:"GO:0052822"(DNA-3-methylguanine glycosylase activity)|interpro:IPR003180("Methylpurine-DNA glycosylase (MPG)")|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR036995|mint:P29372|rcsb pdb:1BNK|rcsb pdb:1EWN|rcsb pdb:1F4R|rcsb pdb:1F6O|rcsb pdb:3QI5|rcsb pdb:3UBY|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-110357|refseq:NP_001015052.1|refseq:NP_002425.2|refseq:NP_001015054.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:DIssmhwGHsxiJoewCmV2zDEmSuI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P27797	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P27708	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P27695	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P27348	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359854|uniprotkb:Q567U5|uniprotkb:Q5TZU8|uniprotkb:Q9UP48|uniprotkb:D6W4Z5|ensembl:ENSP00000238081|ensembl:ENSP00000371267	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:1433t_human(display_long)|uniprotkb:YWHAQ(gene name)|psi-mi:YWHAQ(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)|uniprotkb:14-3-3 protein T-cell(gene name synonym)|uniprotkb:Protein HS1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006817.1|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P27348|rcsb pdb:2BTP|rcsb pdb:5IQP|rcsb pdb:6BCR|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6KZG|rcsb pdb:6KZH|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9614399|ensembl:ENSG00000134308(gene)|ensembl:ENST00000238081(transcript)|ensembl:ENST00000381844(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|dip:DIP-27584N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:3I07h/wy8qcwUJqvO1RA76qnW5U9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P26639	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042683|uniprotkb:Q96FP5|uniprotkb:Q9BWA6|uniprotkb:A8K8I1|ensembl:ENSP00000265112|ensembl:ENSP00000424387|uniprotkb:B4DEG8	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sytc_human(display_long)|uniprotkb:TARS1(gene name)|psi-mi:TARS1(display_short)|uniprotkb:TARS(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase(gene name synonym)|uniprotkb:Threonyl-tRNA synthetase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_689508.3|refseq:NP_001245367.1|rcsb pdb:4HWT|rcsb pdb:4P3N|rcsb pdb:4TTV|rcsb pdb:5XLN|reactome:R-HSA-379716|refseq:NP_001245366.1|go:"GO:0005829"(cytosol)|go:"GO:0006435"(threonyl-tRNA aminoacylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002320(Threonyl-tRNA synthetase, class IIa)|interpro:IPR004095(TGS)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|ensembl:ENSG00000113407(gene)|interpro:IPR012676(TGS-like)|ensembl:ENST00000265112(transcript)|ensembl:ENST00000502553(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004829"(threonine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|interpro:IPR012947(Threonyl/alanyl tRNA synthetase, SAD)|interpro:IPR018163|interpro:IPR033728|interpro:IPR036621|mint:P26639|rcsb pdb:1WWT	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Z+rOaI1ZO1TQftfkRn1HhXUqDAk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P26583	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1057009|uniprotkb:Q5U072|uniprotkb:D3DP37|uniprotkb:B2R4K8|ensembl:ENSP00000296503|ensembl:ENSP00000393448|ensembl:ENSP00000404912	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hmgb2_human(display_long)|uniprotkb:HMGB2(gene name)|psi-mi:HMGB2(display_short)|uniprotkb:HMG2(gene name synonym)|uniprotkb:High mobility group protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001124160.1|refseq:NP_001124161.1|refseq:NP_002120.1|ensembl:ENSG00000164104(gene)|ensembl:ENST00000296503(transcript)|ensembl:ENST00000438704(transcript)|ensembl:ENST00000446922(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032075"(positive regulation of nuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0042056"(chemoattractant activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR036910|mint:P26583|reactome:R-HSA-140342	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:ACzaSeIwT3vM4ZgpCSSlzA6nd4U9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P25705	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P25685	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P24752	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051459|uniprotkb:B2R6H1|uniprotkb:G3XAB4|uniprotkb:Q96FG8|ensembl:ENSP00000265838	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:thil_human(display_long)|uniprotkb:Acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:T2(gene name synonym)|uniprotkb:ACAT1(gene name)|psi-mi:ACAT1(display_short)|uniprotkb:ACAT(gene name synonym)|uniprotkb:MAT(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000010.1|ensembl:ENSG00000075239(gene)|ensembl:ENST00000265838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0007420"(brain development)|go:"GO:0009725"(response to hormone)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016453"(C-acetyltransferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046356"(acetyl-CoA catabolic process)|go:"GO:0046952"(ketone body catabolic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072229"(metanephric proximal convoluted tubule development)|go:"GO:0120225"(coenzyme A binding)|go:"GO:1902224"(ketone body metabolic process)|go:"GO:1902860"(propionyl-CoA biosynthetic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|rcsb pdb:2F2S|rcsb pdb:2IB7|rcsb pdb:2IB8|rcsb pdb:2IB9|rcsb pdb:2IBU|rcsb pdb:2IBW|rcsb pdb:2IBY|reactome:R-HSA-70895|reactome:R-HSA-77108|reactome:R-HSA-77111	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:UYAY+kDdcJqx/hrDFoXH9rgtm/E9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P24539	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:n1HuorsLzONcID7ccOL9qEsODLE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P23921	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-717006|uniprotkb:Q9UNN2|ensembl:ENSP00000300738	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rir1_human(display_long)|uniprotkb:Ribonucleoside-diphosphate reductase subunit M1(gene name synonym)|uniprotkb:Ribonucleotide reductase large subunit(gene name synonym)|uniprotkb:RRM1(gene name)|psi-mi:RRM1(display_short)|uniprotkb:RR1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001024.1|refseq:NP_001304993.1|refseq:NP_001304994.1|ensembl:ENSG00000167325(gene)|ensembl:ENST00000300738(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004748"(ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005829"(cytosol)|go:"GO:0005971"(ribonucleoside-diphosphate reductase complex)|go:"GO:0006206"(pyrimidine nucleobase metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0008584"(male gonad development)|go:"GO:0009263"(deoxyribonucleotide biosynthetic process)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061731"(ribonucleoside-diphosphate reductase activity)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000788(Ribonucleotide reductase large subunit, C-terminal)|interpro:IPR005144(ATP-cone)|interpro:IPR008926(Ribonucleotide reductase R1 subunit, N-terminal)|interpro:IPR013346(Ribonucleoside-diphosphate reductase, alpha subunit)|interpro:IPR013509(Ribonucleotide reductase large subunit, N-terminal)|interpro:IPR039718|rcsb pdb:2WGH|rcsb pdb:3HNC|rcsb pdb:3HND|rcsb pdb:3HNE|rcsb pdb:3HNF|rcsb pdb:4X3V|rcsb pdb:5D1Y|rcsb pdb:5TUS|rcsb pdb:6AUI|rcsb pdb:6L3R|rcsb pdb:6L7L|rcsb pdb:6LKM|reactome:R-HSA-499943|dip:DIP-24233N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:3+XYBQzGh1wi495ZTSvHbYvUXZQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P23193	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2608271|uniprotkb:A6NF25|uniprotkb:A8K339|uniprotkb:Q15563|uniprotkb:Q6FG87|ensembl:ENSP00000428426	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tcea1_human(display_long)|uniprotkb:TCEA1(gene name)|psi-mi:TCEA1(display_short)|uniprotkb:GTF2S(gene name synonym)|uniprotkb:TFIIS(gene name synonym)|uniprotkb:Transcription elongation factor S-II protein 1(gene name synonym)|uniprotkb:Transcription elongation factor TFIIS.o(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006747.1|refseq:NP_958845.1|ensembl:ENSG00000187735(gene)|ensembl:ENST00000521604(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1901919"(positive regulation of exoribonuclease activity)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR006289(Transcription elongation factor, TFIIS)|interpro:IPR017923|interpro:IPR035100|interpro:IPR035441|interpro:IPR036575|mint:P23193|reactome:R-HSA-167243|reactome:R-HSA-167246|rcsb pdb:1TFI|reactome:R-HSA-167287|rcsb pdb:3NDQ|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:6O9L|reactome:R-HSA-112382|reactome:R-HSA-167290|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-48480N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:88QvzePEd32tHYxrij2EoOYkaLk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P22695	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P22314	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-709688|uniprotkb:Q96E13|uniprotkb:Q5JRR8|ensembl:ENSP00000338413|ensembl:ENSP00000366568	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:uba1_human(display_long)|uniprotkb:Ubiquitin-activating enzyme E1(gene name synonym)|uniprotkb:Protein A1S9(gene name synonym)|uniprotkb:UBA1(gene name)|psi-mi:UBA1(display_short)|uniprotkb:A1S9T(gene name synonym)|uniprotkb:UBE1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003325.2|refseq:NP_695012.1|refseq:XP_016885269.1|refseq:XP_016885270.1|dip:DIP-33686N|ensembl:ENSG00000130985(gene)|ensembl:ENST00000335972(transcript)|ensembl:ENST00000377351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004839"(ubiquitin activating enzyme activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000011(Ubiquitin-activating enzyme, E1)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR018075|interpro:IPR018965|interpro:IPR019572|interpro:IPR032418|interpro:IPR032420|interpro:IPR033127|interpro:IPR035985|interpro:IPR038252|interpro:IPR042063|interpro:IPR042302|interpro:IPR042449|mint:P22314|rcsb pdb:4P22|rcsb pdb:6DC6|reactome:R-HSA-8866652|reactome:R-HSA-983168	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:q+vEeA0XLST0Zz173bmEt0dNbDE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P22234	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P22102	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356297|ensembl:ENSP00000371236|ensembl:ENSP00000371253|ensembl:ENSP00000371261|ensembl:ENSP00000459391|ensembl:ENSP00000459532|ensembl:ENSP00000461700|uniprotkb:D3DSF3|uniprotkb:D3DSF4|uniprotkb:O14659|uniprotkb:A8KA32|uniprotkb:A8K945|uniprotkb:Q52M77	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pur2_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short)|uniprotkb:PRGS(gene name synonym)|uniprotkb:PGFT(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0046084"(adenine biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|ensembl:ENST00000571089(transcript)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|ensembl:ENST00000573055(transcript)|ensembl:ENST00000575273(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|interpro:IPR016185(PreATP-grasp-like fold)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR016188(PurM, N-terminal-like)|ensembl:ENSG00000159131(gene)|ensembl:ENSG00000262473(gene)|ensembl:ENST00000381815(transcript)|ensembl:ENST00000381831(transcript)|ensembl:ENST00000381839(transcript)|interpro:IPR020560|interpro:IPR020561|interpro:IPR020562|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|mint:P22102|rcsb pdb:1MEJ|rcsb pdb:1MEN|rcsb pdb:1MEO|rcsb pdb:1NJS|rcsb pdb:1RBM|rcsb pdb:1RBQ|rcsb pdb:1RBY|rcsb pdb:1RBZ|rcsb pdb:1RC0|rcsb pdb:1RC1|rcsb pdb:1ZLX|rcsb pdb:1ZLY|rcsb pdb:2QK4|rcsb pdb:2V9Y|rcsb pdb:4EW1|rcsb pdb:4EW2|rcsb pdb:4EW3|rcsb pdb:4ZYT|interpro:IPR020559|rcsb pdb:4ZYU|rcsb pdb:4ZYV|rcsb pdb:4ZYW|rcsb pdb:4ZYX|rcsb pdb:4ZYY|rcsb pdb:4ZYZ|rcsb pdb:4ZZ0|rcsb pdb:4ZZ1|rcsb pdb:4ZZ2|rcsb pdb:5J9F|rcsb pdb:7JG0|rcsb pdb:4ZZ3|refseq:NP_000810.1|refseq:NP_001129477.1|refseq:NP_001129478.1|refseq:NP_780294.1|rcsb pdb:7JG4|reactome:R-HSA-73817|rcsb pdb:7JG3|refseq:XP_011527828.1|refseq:XP_006724052.1|refseq:XP_006724053.1|refseq:XP_005260998.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7Iy33CtBsB8LHZFDP5mZ3eRX8pU9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P21912	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1056481|uniprotkb:Q9NQ12|uniprotkb:Q0QEY7|uniprotkb:B2R545|ensembl:ENSP00000364649	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sdhb_human(display_long)|uniprotkb:SDHB(gene name)|psi-mi:SDHB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002991.2|ensembl:ENSG00000117118(gene)|ensembl:ENST00000375499(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-39666N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7xnswe3IVEFJiXqGhxF0Az3EmvE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P19623	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1056183|uniprotkb:Q15511|uniprotkb:B1AKP9|ensembl:ENSP00000366156	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:spee_human(display_long)|uniprotkb:SRM(gene name)|psi-mi:SRM(display_short)|uniprotkb:SPS1(gene name synonym)|uniprotkb:SRML1(gene name synonym)|uniprotkb:Putrescine aminopropyltransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003123.2|ensembl:ENSG00000116649(gene)|ensembl:ENST00000376957(transcript)|go:"GO:0004766"(spermidine synthase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006595"(polyamine metabolic process)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008295"(spermidine biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001045(Spermine synthase)|interpro:IPR029063|interpro:IPR030373|interpro:IPR030374|interpro:IPR030668|interpro:IPR035246|interpro:IPR037163|rcsb pdb:2O05|rcsb pdb:2O06|rcsb pdb:2O07|rcsb pdb:2O0L|rcsb pdb:3RW9|reactome:R-HSA-351202	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:VNjR3N2SwRzXIokl23Lis1pV3Pg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P18085	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1237085|ensembl:ENSP00000306010|uniprotkb:P21371|uniprotkb:B2R7J7	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:arf4_human(display_long)|uniprotkb:ARF4(gene name)|psi-mi:ARF4(display_short)|uniprotkb:ARF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000168374(gene)|ensembl:ENST00000303436(transcript)|refseq:NP_001651.1|dip:DIP-38214N|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0060271"(cilium assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P18085|rcsb pdb:1Z6X|reactome:R-HSA-5620916|reactome:R-HSA-6807878|reactome:R-HSA-6811434	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:AN3aBuSStAMrmkqq1HEDQtOiCy49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P17812	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1042983|uniprotkb:Q5VW67|uniprotkb:Q96GK6|ensembl:ENSP00000361699|ensembl:ENSP00000497602|ensembl:ENSP00000497744|uniprotkb:D3DPW1|uniprotkb:B4DR64	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pyrg1_human(display_long)|uniprotkb:CTPS1(gene name)|psi-mi:CTPS1(display_short)|uniprotkb:CTP synthetase 1(gene name synonym)|uniprotkb:CTPS(gene name synonym)|uniprotkb:UTP--ammonia ligase 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000171793(gene)|ensembl:ENST00000372616(transcript)|ensembl:ENST00000649124(transcript)|ensembl:ENST00000650070(transcript)|go:"GO:0003883"(CTP synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019856"(pyrimidine nucleobase biosynthetic process)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044210"('de novo' CTP biosynthetic process)|go:"GO:0097268"(cytoophidium)|interpro:IPR004468(CTP synthase)|interpro:IPR017456(CTP synthase, N-terminal)|interpro:IPR017926|interpro:IPR027417|interpro:IPR029062|interpro:IPR033828|mint:P17812|rcsb pdb:2VO1|rcsb pdb:5U03|reactome:R-HSA-499943|refseq:NP_001288166.1|refseq:NP_001896.2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:0QkxA3YRejXU0X7dk7zf1XeAMt89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P17066	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355106|uniprotkb:Q8IYK7|uniprotkb:Q9BT95|uniprotkb:Q1HBA8|ensembl:ENSP00000310219	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hsp76_human(display_long)|uniprotkb:HSPA6(gene name)|psi-mi:HSPA6(display_short)|uniprotkb:HSP70B'(gene name synonym)|uniprotkb:Heat shock 70 kDa protein B'(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002146.2|ensembl:ENSG00000173110(gene)|ensembl:ENST00000309758(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P17066|rcsb pdb:3FE1|reactome:R-HSA-3371453|reactome:R-HSA-6798695	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:AcNwJ2S/RD3n/8iRNy5ioetVZ+U9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P16949	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-445909|uniprotkb:A2A2D1|uniprotkb:B7Z8N4|uniprotkb:D3DPJ5|uniprotkb:B2R4E7|ensembl:ENSP00000350531|ensembl:ENSP00000363409|ensembl:ENSP00000382633|ensembl:ENSP00000387858	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:stmn1_human(display_long)|uniprotkb:Phosphoprotein p19(gene name synonym)|uniprotkb:Leukemia-associated phosphoprotein p18(gene name synonym)|uniprotkb:Oncoprotein 18(gene name synonym)|uniprotkb:pp17(gene name synonym)|uniprotkb:Prosolin(gene name synonym)|uniprotkb:Metablastin(gene name synonym)|uniprotkb:Protein Pr22(gene name synonym)|uniprotkb:STMN1(gene name)|psi-mi:STMN1(display_short)|uniprotkb:LAP18(gene name synonym)|uniprotkb:OP18(gene name synonym)|uniprotkb:C1orf215(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001138926.1|refseq:NP_005554.1|refseq:NP_981944.1|refseq:NP_981946.1|ensembl:ENST00000357865(transcript)|ensembl:ENST00000374291(transcript)|ensembl:ENST00000399728(transcript)|ensembl:ENST00000455785(transcript)|go:"GO:0000281"(mitotic cytokinesis)|ensembl:ENSG00000117632(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0009615"(response to virus)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|mint:P16949|interpro:IPR000956(Stathmin)|interpro:IPR030514|interpro:IPR036002|reactome:R-HSA-1251985	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:gew+NqUuLLolCLCXOyXIZkRieIs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P16152	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-351348|uniprotkb:Q3LHW8|uniprotkb:B2RBZ7|ensembl:ENSP00000290349|uniprotkb:B4DFK7	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cbr1_human(display_long)|uniprotkb:SDR21C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 21C member 1(gene name synonym)|uniprotkb:CBR1(gene name)|psi-mi:CBR1(display_short)|uniprotkb:CBR(gene name synonym)|uniprotkb:CRN(gene name synonym)|uniprotkb:NADPH-dependent carbonyl reductase 1(gene name synonym)|uniprotkb:"Prostaglandin-E(2) 9-reductase"(gene name synonym)|uniprotkb:Prostaglandin 9-ketoreductase(gene name synonym)|uniprotkb:"15-hydroxyprostaglandin dehydrogenase [NADP(+)]"(gene name synonym)|uniprotkb:20-beta-hydroxysteroid dehydrogenase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001748.1|ensembl:ENSG00000159228(gene)|ensembl:ENST00000290349(transcript)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005829"(cytosol)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0017144"|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0042373"(vitamin K metabolic process)|go:"GO:0047020"("15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity")|go:"GO:0047021"("15-hydroxyprostaglandin dehydrogenase (NADP+) activity")|go:"GO:0050221"(prostaglandin-E2 9-reductase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:P16152|rcsb pdb:1WMA|rcsb pdb:2PFG|rcsb pdb:3BHI|rcsb pdb:3BHJ|rcsb pdb:3BHM|rcsb pdb:4Z3D|reactome:R-HSA-2162123|refseq:NP_001273718.1|dip:DIP-33136N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:ROzNiYne9nXfvDC9Hi3Ni6M7ILA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P15374	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-954554|uniprotkb:Q5TBK8|uniprotkb:Q6IBE9|ensembl:ENSP00000366819|uniprotkb:B2R970	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:uchl3_human(display_long)|uniprotkb:Ubiquitin thioesterase L3(gene name synonym)|uniprotkb:UCHL3(gene name)|psi-mi:UCHL3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001257881.1|refseq:NP_005993.1|ensembl:ENSG00000118939(gene)|ensembl:ENST00000377595(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043687"(post-translational protein modification)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR036959|interpro:IPR038765|rcsb pdb:1UCH|rcsb pdb:1XD3|rcsb pdb:6ISU|rcsb pdb:6QML|reactome:R-HSA-5689603|reactome:R-HSA-8866652|reactome:R-HSA-8951664|dip:DIP-29135N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:cPnctBpxrgvBKBSaQmhCsyd2nRM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P15311	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P14625	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P14618	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:dDaoXCaqd0x6qFSElvngHusttuk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P14324	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-948245|ensembl:ENSP00000349078|ensembl:ENSP00000357340|uniprotkb:Q96G29|uniprotkb:D3DV91|uniprotkb:E9PCI9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fpps_human(display_long)|uniprotkb:Farnesyl diphosphate synthase(gene name synonym)|uniprotkb:FDPS(gene name)|psi-mi:FDPS(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:KIAA1293(gene name synonym)|uniprotkb:"(2E,6E)-farnesyl diphosphate synthase"(gene name synonym)|uniprotkb:Dimethylallyltranstransferase(gene name synonym)|uniprotkb:Geranyltranstransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000160752(gene)|ensembl:ENST00000356657(transcript)|ensembl:ENST00000368356(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004161"(dimethylallyltranstransferase activity)|go:"GO:0004337"(geranyltranstransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0033384"(geranyl diphosphate biosynthetic process)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|go:"GO:0005654"(nucleoplasm)|rcsb pdb:1YQ7|rcsb pdb:1ZW5|rcsb pdb:2F7M|rcsb pdb:2F89|rcsb pdb:2F8C|rcsb pdb:2F8Z|rcsb pdb:2F92|rcsb pdb:2F94|rcsb pdb:2F9K|rcsb pdb:2OPM|rcsb pdb:2OPN|rcsb pdb:2QIS|rcsb pdb:2RAH|rcsb pdb:2VF6|rcsb pdb:3B7L|rcsb pdb:3CP6|rcsb pdb:3N1V|rcsb pdb:3N1W|rcsb pdb:3N3L|rcsb pdb:3N45|rcsb pdb:3N46|rcsb pdb:1YV5|rcsb pdb:3N49|rcsb pdb:3N5H|rcsb pdb:3N5J|rcsb pdb:3N6K|rcsb pdb:3RYE|rcsb pdb:3S4J|rcsb pdb:4DEM|rcsb pdb:4GA3|rcsb pdb:4H5D|rcsb pdb:4H5E|rcsb pdb:4JVJ|rcsb pdb:4KFA|rcsb pdb:4KPD|rcsb pdb:4KPJ|rcsb pdb:4KQ5|rcsb pdb:4KQS|rcsb pdb:4KQU|rcsb pdb:4L2X|rcsb pdb:4LFV|rcsb pdb:4LPG|rcsb pdb:4LPH|rcsb pdb:4N1Z|rcsb pdb:4N9U|rcsb pdb:4NFI|rcsb pdb:4NFJ|rcsb pdb:4NFK|rcsb pdb:4NG6|rcsb pdb:4NKE|rcsb pdb:4NKF|rcsb pdb:4NUA|rcsb pdb:4OGU|rcsb pdb:4P0V|rcsb pdb:4P0W|rcsb pdb:4P0X|rcsb pdb:4PVX|rcsb pdb:4PVY|rcsb pdb:4H5C|rcsb pdb:4Q23|rcsb pdb:4QPF|rcsb pdb:4QXS|rcsb pdb:4RXA|rcsb pdb:4XQR|rcsb pdb:4XQS|rcsb pdb:4XQT|reactome:R-HSA-2426168|rcsb pdb:5CG6|rcsb pdb:5DGM|rcsb pdb:5CG5|rcsb pdb:5DGN|rcsb pdb:5DGS|rcsb pdb:5DIQ|rcsb pdb:5DJP|rcsb pdb:5DJR|rcsb pdb:5DJV|rcsb pdb:5JA0|rcsb pdb:5JUZ|rcsb pdb:5JV0|rcsb pdb:5JV1|rcsb pdb:5JV2|rcsb pdb:5KSX|rcsb pdb:5YGI|rcsb pdb:6N7Y|rcsb pdb:6N7Z|rcsb pdb:6N82|rcsb pdb:6N83|rcsb pdb:6OAG|rcsb pdb:6OAH|reactome:R-HSA-191273|refseq:NP_001129293.1|refseq:NP_001129294.1|refseq:NP_001229753.1|refseq:NP_001229754.1|refseq:NP_001995.1|refseq:XP_005245019.1|refseq:XP_005245020.1|dip:DIP-50059N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:cLrS58XE4dKJiiK96hQt7JPO5T89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P13797	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-698052|uniprotkb:B1AQ09|uniprotkb:Q86YI6|uniprotkb:A8K579|uniprotkb:B4DGB4|uniprotkb:B7Z6M1|ensembl:ENSP00000348163|ensembl:ENSP00000445339	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:plst_human(display_long)|uniprotkb:T-plastin(gene name synonym)|uniprotkb:PLS3(gene name)|psi-mi:PLS3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001129497.1|refseq:NP_005023.2|refseq:XP_011535836.1|refseq:NP_001165806.1|refseq:NP_001269266.1|refseq:NP_001269267.1|ensembl:ENSG00000102024(gene)|ensembl:ENST00000355899(transcript)|ensembl:ENST00000539310(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0032432"(actin filament bundle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060348"(bone development)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|mint:P13797|rcsb pdb:1AOA|rcsb pdb:1WJO	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:RWAS8uhDHEtqdDd1gfsqDDyvvsE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P13639	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P13010	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P12277	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P12004	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358311|uniprotkb:B2R897|uniprotkb:D3DW02|ensembl:ENSP00000368438|ensembl:ENSP00000368458	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pcna_human(display_long)|uniprotkb:PCNA(gene name)|psi-mi:PCNA(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002583.1|refseq:NP_872590.1|ensembl:ENSG00000132646(gene)|ensembl:ENST00000379143(transcript)|ensembl:ENST00000379160(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030894"(replisome)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0043626"(PCNA complex)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P12004|rcsb pdb:1AXC|rcsb pdb:1U76|rcsb pdb:1U7B|rcsb pdb:1UL1|rcsb pdb:1VYJ|rcsb pdb:1VYM|rcsb pdb:1W60|rcsb pdb:2ZVK|rcsb pdb:2ZVL|rcsb pdb:2ZVM|rcsb pdb:3JA9|rcsb pdb:3P87|rcsb pdb:3TBL|rcsb pdb:3VKX|rcsb pdb:3WGW|rcsb pdb:4D2G|rcsb pdb:4RJF|rcsb pdb:4ZTD|rcsb pdb:5E0T|rcsb pdb:5E0U|rcsb pdb:5E0V|rcsb pdb:5IY4|rcsb pdb:5MAV|rcsb pdb:5MLO|rcsb pdb:5MLW|reactome:R-HSA-5651801|rcsb pdb:5MOM|rcsb pdb:5YCO|rcsb pdb:5YD8|rcsb pdb:6CBI|rcsb pdb:6EHT|rcsb pdb:6FCM|rcsb pdb:6FCN|rcsb pdb:6GIS|rcsb pdb:6GWS|rcsb pdb:6HVO|rcsb pdb:6K3A|rcsb pdb:6QC0|rcsb pdb:6QCG|rcsb pdb:6S1M|rcsb pdb:6S1N|rcsb pdb:6S1O|rcsb pdb:6TNY|rcsb pdb:6TNZ|rcsb pdb:6VVO|rcsb pdb:7EFA|rcsb pdb:7KQ0|rcsb pdb:7KQ1|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1362277|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174437|reactome:R-HSA-4615885|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804114|reactome:R-HSA-69091|reactome:R-HSA-69166|reactome:R-HSA-69183|reactome:R-HSA-69205|reactome:R-HSA-8866654|reactome:R-HSA-5655862|dip:DIP-1098N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5JUv5dKFwQAAaXm5aEiwCXVoAOM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P11142	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P11021	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P10809	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P10768	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052334|uniprotkb:Q5TBU8|uniprotkb:Q5TBV0|uniprotkb:Q5TBV2|uniprotkb:Q9BVJ2|ensembl:ENSP00000367992	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:estd_human(display_long)|uniprotkb:Esterase D(gene name synonym)|uniprotkb:ESD(gene name)|psi-mi:ESD(display_short)|uniprotkb:Methylumbelliferyl-acetate deacetylase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001975.1|refseq:XP_011533256.1|refseq:XP_005266335.1|ensembl:ENSG00000139684(gene)|ensembl:ENST00000378720(transcript)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0018738"(S-formylglutathione hydrolase activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0046294"(formaldehyde catabolic process)|go:"GO:0047374"(methylumbelliferyl-acetate deacetylase activity)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000801(Putative esterase)|interpro:IPR014186(S-formylglutathione hydrolase)|interpro:IPR029058|rcsb pdb:3FCX|reactome:R-HSA-156590	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:I8V/PLKeeDbsSgkLk0BADWVbDdg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P10606	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1053725|uniprotkb:Q96J18|uniprotkb:Q99610|uniprotkb:Q53YB7|ensembl:ENSP00000258424	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cox5b_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Vb(gene name synonym)|uniprotkb:COX5B(gene name)|psi-mi:COX5B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001853.2|ensembl:ENSG00000135940(gene)|ensembl:ENST00000258424(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:EG8kMS2jKMWzQQokTXS2bYk4fHc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P10599	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|uniprotkb:Q9UDG5|intact:EBI-1042712|ensembl:ENSP00000363641	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|ensembl:ENSG00000136810(gene)|ensembl:ENST00000374517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:1W1C|rcsb pdb:1W1E|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P09936	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-714860|uniprotkb:Q71UM0|intact:EBI-1049220|uniprotkb:Q4W5K6|ensembl:ENSP00000284440|ensembl:ENSP00000422542	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:uchl1_human(display_long)|uniprotkb:Ubiquitin thioesterase L1(gene name synonym)|uniprotkb:Neuron cytoplasmic protein 9.5(gene name synonym)|uniprotkb:PGP 9.5(gene name synonym)|uniprotkb:UCHL1(gene name)|psi-mi:UCHL1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004172.2|ensembl:ENSG00000154277(gene)|ensembl:ENST00000284440(transcript)|ensembl:ENST00000503431(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007412"(axon target recognition)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016874"(ligase activity)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031694"(alpha-2A adrenergic receptor binding)|go:"GO:0035690"|go:"GO:0042755"(eating behavior)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0050905"(neuromuscular process)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR030297|interpro:IPR036959|interpro:IPR038765|mint:P09936|rcsb pdb:2ETL|rcsb pdb:2LEN|rcsb pdb:3IFW|rcsb pdb:3IRT|rcsb pdb:3KVF|rcsb pdb:3KW5|rcsb pdb:4DM9|rcsb pdb:4JKJ|reactome:R-HSA-5689603|go:"GO:0055001"(muscle cell development)|dip:DIP-36620N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:bQ3cxdH+e5fTg7KZ1wjHcOd9cIs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P09669	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-715040|uniprotkb:B2R4D7|ensembl:ENSP00000297564|ensembl:ENSP00000428150|ensembl:ENSP00000428702|ensembl:ENSP00000428895|ensembl:ENSP00000428965|ensembl:ENSP00000429410|ensembl:ENSP00000429707|ensembl:ENSP00000429714|ensembl:ENSP00000429755|ensembl:ENSP00000429991	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cox6c_human(display_long)|uniprotkb:COX6C(gene name)|psi-mi:COX6C(display_short)|uniprotkb:Cytochrome c oxidase polypeptide VIc(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004365.1|refseq:XP_016868509.1|ensembl:ENSG00000164919(gene)|ensembl:ENST00000297564(transcript)|ensembl:ENST00000517682(transcript)|ensembl:ENST00000518171(transcript)|ensembl:ENST00000520271(transcript)|ensembl:ENST00000520468(transcript)|ensembl:ENST00000520517(transcript)|ensembl:ENST00000522934(transcript)|ensembl:ENST00000522940(transcript)|ensembl:ENST00000523016(transcript)|ensembl:ENST00000524245(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004204(Cytochrome c oxidase subunit VIc)|interpro:IPR034884|interpro:IPR037169|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0006091"(generation of precursor metabolites and energy)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Zha4dqasvkWw3ACebJNflgxCVKo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P09622	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-353366|uniprotkb:Q14131|uniprotkb:Q14167|uniprotkb:Q59EV8|uniprotkb:Q8WTS4|uniprotkb:B2R5X0|ensembl:ENSP00000205402|ensembl:ENSP00000390667|uniprotkb:B4DHG0|uniprotkb:B4DT69	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dldh_human(display_long)|uniprotkb:DLD(gene name)|psi-mi:DLD(display_short)|uniprotkb:GCSL(gene name synonym)|uniprotkb:LAD(gene name synonym)|uniprotkb:PHE3(gene name synonym)|uniprotkb:Dihydrolipoamide dehydrogenase(gene name synonym)|uniprotkb:Glycine cleavage system L protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001276679.1|refseq:NP_000099.2|rcsb pdb:6I4Z|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006508"(proteolysis)|go:"GO:0007369"(gastrulation)|go:"GO:0007568"(aging)|go:"GO:0009106"(lipoate metabolic process)|go:"GO:0031514"(motile cilium)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043159"(acrosomal matrix)|go:"GO:0043544"(lipoamide binding)|ensembl:ENSG00000091140(gene)|ensembl:ENST00000205402(transcript)|ensembl:ENST00000417551(transcript)|go:"GO:0004148"(dihydrolipoyl dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|reactome:R-HSA-204174|reactome:R-HSA-389661|reactome:R-HSA-5362517|reactome:R-HSA-6783984|reactome:R-HSA-70268|reactome:R-HSA-70895|reactome:R-HSA-71064|reactome:R-HSA-71403|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051068"(dihydrolipoamide metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0106077"(histone succinylation)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|interpro:IPR006258(Dihydrolipoamide dehydrogenase)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR036188|mint:P09622|rcsb pdb:1ZMC|rcsb pdb:1ZMD|rcsb pdb:1ZY8|rcsb pdb:2F5Z|rcsb pdb:3RNM|rcsb pdb:5J5Z|rcsb pdb:5NHG|rcsb pdb:6HG8|rcsb pdb:6I4P|rcsb pdb:6I4Q|rcsb pdb:6I4R|rcsb pdb:6I4S|rcsb pdb:6I4T|rcsb pdb:6I4U|refseq:NP_001276680.1|refseq:NP_001276681.1|dip:DIP-29027N	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:7613492C516F3835	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7Yf9KyBWf18686aOXVUwab65rl89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P09211	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607|uniprotkb:Q5TZY3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000843.1|ensembl:ENSG00000084207(gene)|go:"GO:0000302"(response to reactive oxygen species)|ensembl:ENST00000398606(transcript)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009890"(negative regulation of biosynthetic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0035732"(nitric oxide storage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7GSS|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P08243	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-722989|uniprotkb:P08184|uniprotkb:Q15666|uniprotkb:Q549T9|uniprotkb:Q96HD0|ensembl:ENSP00000175506|ensembl:ENSP00000377845|ensembl:ENSP00000377846|uniprotkb:A4D1I8|uniprotkb:D6W5R3|uniprotkb:B4DXZ1|uniprotkb:B7ZAA9|uniprotkb:E9PCI3|uniprotkb:E9PCX6	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:asns_human(display_long)|uniprotkb:Glutamine-dependent asparagine synthetase(gene name synonym)|uniprotkb:Cell cycle control protein TS11(gene name synonym)|uniprotkb:ASNS(gene name)|psi-mi:ASNS(display_short)|uniprotkb:TS11(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001171546.1|refseq:NP_001171547.1|refseq:NP_001171548.1|refseq:NP_001664.3|refseq:NP_597680.2|refseq:NP_899199.2|ensembl:ENSG00000070669(gene)|ensembl:ENST00000175506(transcript)|ensembl:ENST00000394308(transcript)|ensembl:ENST00000394309(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004066"("asparagine synthase (glutamine-hydrolyzing) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006529"(asparagine biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0031427"(response to methotrexate)|go:"GO:0032354"(response to follicle-stimulating hormone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043200"(response to amino acid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0070981"(L-asparagine biosynthetic process)|interpro:IPR001962(Asparagine synthase)|interpro:IPR006426(Asparagine synthase, glutamine-hydrolyzing)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR017932|interpro:IPR029055|interpro:IPR033738|rcsb pdb:6GQ3|reactome:R-HSA-380994|reactome:R-HSA-8963693|reactome:R-HSA-9633012|reactome:R-HSA-9648895	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:McR8Ve0DzWhe3JWMYLsCRChiBaY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P08107	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-629985|uniprotkb:P19790|uniprotkb:Q5JQI4|uniprotkb:Q5SP17|uniprotkb:Q9UQL9|uniprotkb:Q9UQM0|intact:EBI-4404728|uniprotkb:B4E3B6	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hsp71_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSPA1B(gene name)|psi-mi:HSPA1B(display_short)|uniprotkb:Heat shock 70 kDa protein 1/2(gene name synonym)|uniprotkb:HSX70(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005336.3|refseq:NP_005337.2|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|go:"GO:0005829"(cytosol)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0016607"(nuclear speck)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0030529"|go:"GO:0005524"(ATP binding)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0042026"(protein refolding)|go:"GO:0006986"(response to unfolded protein)|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:3A8Y|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0031982"(vesicle)|go:"GO:0010467"(gene expression)|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0050821"(protein stabilization)|go:"GO:0005654"(nucleoplasm)|go:"GO:1900034"(regulation of cellular response to heat)|rcsb pdb:4WV5|rcsb pdb:4WV7|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:4IO8|rcsb pdb:2LMG|go:"GO:0016235"(aggresome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0001618"(virus receptor activity)|rcsb pdb:4J8F|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016234"(inclusion body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044822"|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0005814"(centriole)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042623"|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR029047|interpro:IPR029048|ensembl:ENST00000375650|ensembl:ENST00000375651|ensembl:ENST00000391548|ensembl:ENST00000391555|ensembl:ENST00000400040|ensembl:ENST00000430065|ensembl:ENST00000433487|ensembl:ENST00000441618|ensembl:ENST00000445736|ensembl:ENST00000450744|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005925"(focal adhesion)|go:"GO:0031397"(negative regulation of protein ubiquitination)|rcsb pdb:4PO2|reactome:REACT_25325|reactome:REACT_6198|ensembl:ENSG00000204388|ensembl:ENSG00000204389|ensembl:ENSG00000212866|ensembl:ENSG00000215328|ensembl:ENSG00000224501|ensembl:ENSG00000231555|ensembl:ENSG00000232804|ensembl:ENSG00000234475|ensembl:ENSG00000235941|ensembl:ENSG00000237724|ensembl:ENSP00000364801|ensembl:ENSP00000364802|ensembl:ENSP00000375391|ensembl:ENSP00000375399|ensembl:ENSP00000382915|ensembl:ENSP00000393087|ensembl:ENSP00000403530|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907|reactome:REACT_264075|reactome:REACT_264164|reactome:REACT_264487	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:NFv4uj12xAWIr+OltarRlLDPr949606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P07919	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1224427|uniprotkb:Q5TDF6|uniprotkb:Q6LDB8|uniprotkb:Q9BQ91|uniprotkb:D3DQ18|uniprotkb:B2R4V9|ensembl:ENSP00000309565	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:qcr6_human(display_long)|uniprotkb:UQCRH(gene name)|psi-mi:UQCRH(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase complex 11 kDa protein(gene name synonym)|uniprotkb:Cytochrome c1 non-heme 11 kDa protein(gene name synonym)|uniprotkb:Mitochondrial hinge protein(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Complex III subunit 6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005995.2|ensembl:ENSG00000173660(gene)|ensembl:ENST00000311672(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009060"(aerobic respiration)|interpro:IPR003422(Ubiquinol-cytochrome C reductase hinge)|interpro:IPR023184|interpro:IPR036811|mint:P07919|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:1f1RPTV/dS3CK24n/YSvDPXLm5c9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P07900	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-296047|intact:EBI-1642144|uniprotkb:Q2PP14|ensembl:ENSP00000216281|uniprotkb:Q5CAQ6|uniprotkb:Q5CAQ7|uniprotkb:Q9BVQ5|intact:EBI-2211817|uniprotkb:A8K500|uniprotkb:B3KPJ9	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hs90a_human(display_long)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0009409"(response to cold)|go:"GO:0016020"(membrane)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P07900|rcsb pdb:1BYQ|rcsb pdb:1OSF|rcsb pdb:1UY6|rcsb pdb:1UY7|ensembl:ENST00000216281(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000080824(gene)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043335"(protein unfolding)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|rcsb pdb:1UY9|rcsb pdb:1UYC|rcsb pdb:1UYD|rcsb pdb:1UYE|rcsb pdb:1UYF|rcsb pdb:1UYG|rcsb pdb:1UYH|rcsb pdb:1UYI|rcsb pdb:1UYK|rcsb pdb:1UYL|rcsb pdb:1UY8|rcsb pdb:1YC1|rcsb pdb:1YC3|rcsb pdb:1YC4|rcsb pdb:1YER|rcsb pdb:1YES|rcsb pdb:1YET|rcsb pdb:2BSM|rcsb pdb:2BT0|rcsb pdb:2BUG|rcsb pdb:2WI1|rcsb pdb:2WI2|rcsb pdb:2WI3|rcsb pdb:2WI4|rcsb pdb:2WI5|rcsb pdb:2WI6|rcsb pdb:2WI7|rcsb pdb:2XAB|rcsb pdb:2XDK|rcsb pdb:2XDL|rcsb pdb:2XDS|rcsb pdb:2XDU|rcsb pdb:2XDX|rcsb pdb:2XHR|rcsb pdb:2XHT|rcsb pdb:2XHX|rcsb pdb:2XJG|rcsb pdb:2XJJ|rcsb pdb:2XJX|rcsb pdb:2XK2|rcsb pdb:2YE2|rcsb pdb:2YE3|rcsb pdb:2YE4|rcsb pdb:2YE5|rcsb pdb:2YE6|rcsb pdb:2YE7|rcsb pdb:2YE8|rcsb pdb:2YE9|rcsb pdb:2YEA|rcsb pdb:2YEB|rcsb pdb:2BYI|rcsb pdb:2BZ5|rcsb pdb:2C2L|rcsb pdb:2CCS|rcsb pdb:2CCT|rcsb pdb:2CCU|rcsb pdb:2FWY|rcsb pdb:2FWZ|rcsb pdb:2H55|rcsb pdb:2JJC|rcsb pdb:2K5B|rcsb pdb:2QF6|rcsb pdb:2QFO|rcsb pdb:2QG0|rcsb pdb:2QG2|rcsb pdb:2UWD|rcsb pdb:2VCI|rcsb pdb:2BYH|rcsb pdb:2VCJ|rcsb pdb:3B25|rcsb pdb:3B26|rcsb pdb:3B27|rcsb pdb:3B28|rcsb pdb:3BM9|rcsb pdb:3BMY|rcsb pdb:3D0B|rcsb pdb:3EKO|rcsb pdb:3EKR|rcsb pdb:3FT5|rcsb pdb:3FT8|rcsb pdb:3HEK|rcsb pdb:3HHU|rcsb pdb:3HYY|rcsb pdb:3HYZ|rcsb pdb:3HZ1|rcsb pdb:3HZ5|rcsb pdb:3INW|rcsb pdb:3B24|rcsb pdb:3INX|rcsb pdb:3K97|rcsb pdb:3K98|rcsb pdb:2YEC|rcsb pdb:2YED|rcsb pdb:2YEE|rcsb pdb:2YEF|rcsb pdb:2YEG|rcsb pdb:2YEH|rcsb pdb:2YEI|rcsb pdb:2YEJ|rcsb pdb:2YI0|rcsb pdb:2YI5|rcsb pdb:2YI6|rcsb pdb:2YI7|rcsb pdb:2YJW|rcsb pdb:2YJX|rcsb pdb:2YK2|rcsb pdb:2YK9|rcsb pdb:2YKB|rcsb pdb:2YKC|rcsb pdb:2YKE|rcsb pdb:2YKI|rcsb pdb:2YKJ|rcsb pdb:4CWF|rcsb pdb:4CWN|rcsb pdb:4CWO|rcsb pdb:4CWP|rcsb pdb:4CWQ|rcsb pdb:4CWR|rcsb pdb:4CWS|rcsb pdb:4CWT|rcsb pdb:4EEH|rcsb pdb:4EFT|rcsb pdb:4EFU|rcsb pdb:4EGH|rcsb pdb:4EGI|rcsb pdb:4EGK|rcsb pdb:4FCP|rcsb pdb:4FCQ|rcsb pdb:4FCR|rcsb pdb:4HY6|rcsb pdb:4JQL|rcsb pdb:4L8Z|rcsb pdb:4L90|rcsb pdb:4L91|rcsb pdb:5LO5|rcsb pdb:5LO6|rcsb pdb:5LQ9|rcsb pdb:5LR1|rcsb pdb:5LR7|rcsb pdb:5LRL|rcsb pdb:5LRZ|rcsb pdb:5LS1|rcsb pdb:5M4E|rcsb pdb:5M4H|rcsb pdb:5NYH|rcsb pdb:5NYI|rcsb pdb:5OCI|rcsb pdb:5OD7|rcsb pdb:5ODX|rcsb pdb:5T21|rcsb pdb:5VYY|rcsb pdb:5XQD|rcsb pdb:5XQE|rcsb pdb:5XR5|rcsb pdb:5XR9|rcsb pdb:5XRB|rcsb pdb:5XRD|rcsb pdb:5XRE|rcsb pdb:5LO1|rcsb pdb:5ZR3|rcsb pdb:6B99|rcsb pdb:6B9A|rcsb pdb:6CEO|rcsb pdb:6CYG|rcsb pdb:6EI5|rcsb pdb:6EL5|rcsb pdb:6ELN|rcsb pdb:6ELO|rcsb pdb:6ELP|rcsb pdb:6EY8|rcsb pdb:6EY9|rcsb pdb:6EYA|rcsb pdb:6EYB|rcsb pdb:6F1N|rcsb pdb:6FCJ|rcsb pdb:6FDP|rcsb pdb:6GP4|rcsb pdb:6GP8|rcsb pdb:6GPF|rcsb pdb:6GPH|rcsb pdb:6CYH|rcsb pdb:6GPO|rcsb pdb:6GPP|rcsb pdb:6GPR|rcsb pdb:6GPT|rcsb pdb:6GPW|rcsb pdb:6GPY|rcsb pdb:6GQ6|rcsb pdb:6GQR|rcsb pdb:6GQS|rcsb pdb:6GQU|rcsb pdb:6GR1|rcsb pdb:6GR3|rcsb pdb:6GR4|rcsb pdb:6GR5|rcsb pdb:6HHR|rcsb pdb:6KSQ|rcsb pdb:6LR9|rcsb pdb:6LSZ|rcsb pdb:6LT8|rcsb pdb:6LTI|rcsb pdb:6LTK|rcsb pdb:6N8X|rcsb pdb:6OLX|rcsb pdb:6TN5|rcsb pdb:6U98|rcsb pdb:6U99|rcsb pdb:6U9A|rcsb pdb:6U9B|rcsb pdb:7LSZ|rcsb pdb:7LT0|reactome:R-HSA-1227986|reactome:R-HSA-1236382|rcsb pdb:6TN4|reactome:R-HSA-1474151|reactome:R-HSA-168928|reactome:R-HSA-192905|reactome:R-HSA-2029482|reactome:R-HSA-203615|reactome:R-HSA-2565942|reactome:R-HSA-3000484|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-399954|reactome:R-HSA-4420097|reactome:R-HSA-5218920|reactome:R-HSA-5336415|reactome:R-HSA-5601884|reactome:R-HSA-5620912|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8863795|reactome:R-HSA-8939211|reactome:R-HSA-9009391|reactome:R-HSA-9013418|reactome:R-HSA-9018519|reactome:R-HSA-9613829|reactome:R-HSA-9634285|reactome:R-HSA-9646399|reactome:R-HSA-9652282|reactome:R-HSA-9665233|reactome:R-HSA-9664565|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|reactome:R-HSA-9679191|rcsb pdb:3MNR|rcsb pdb:3O0I|rcsb pdb:3OW6|rcsb pdb:3OWB|rcsb pdb:3OWD|rcsb pdb:3Q6M|rcsb pdb:3Q6N|rcsb pdb:3QDD|rcsb pdb:3QTF|rcsb pdb:3R4M|rcsb pdb:3R4N|rcsb pdb:3R4O|rcsb pdb:3R4P|rcsb pdb:3R91|rcsb pdb:3R92|rcsb pdb:3K99|rcsb pdb:3RKZ|rcsb pdb:3RLP|rcsb pdb:3RLQ|rcsb pdb:3RLR|rcsb pdb:4L93|rcsb pdb:4L94|rcsb pdb:4LWE|rcsb pdb:4LWF|rcsb pdb:4LWG|rcsb pdb:4LWH|rcsb pdb:4LWI|rcsb pdb:4NH7|rcsb pdb:4NH8|rcsb pdb:4O04|rcsb pdb:4O05|rcsb pdb:4O07|rcsb pdb:4O09|rcsb pdb:4O0B|rcsb pdb:4R3M|rcsb pdb:4U93|rcsb pdb:4W7T|rcsb pdb:4XIP|rcsb pdb:4XIQ|rcsb pdb:4XIR|rcsb pdb:4XIT|rcsb pdb:4YKQ|rcsb pdb:4YKR|rcsb pdb:4YKT|rcsb pdb:4YKU|rcsb pdb:4YKW|rcsb pdb:4YKX|rcsb pdb:4YKY|rcsb pdb:3T0Z|rcsb pdb:3T10|rcsb pdb:3T1K|rcsb pdb:3T2S|rcsb pdb:3TUH|rcsb pdb:3VHA|rcsb pdb:3VHC|rcsb pdb:3VHD|rcsb pdb:3WHA|rcsb pdb:3WQ9|rcsb pdb:4AIF|rcsb pdb:4AWO|rcsb pdb:4AWP|rcsb pdb:3T0H|rcsb pdb:4AWQ|rcsb pdb:4B7P|rcsb pdb:4BQG|rcsb pdb:4BQJ|rcsb pdb:4CGQ|rcsb pdb:4CGU|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:5CF0|rcsb pdb:5FNC|rcsb pdb:5FND|rcsb pdb:5FNF|rcsb pdb:5GGZ|rcsb pdb:5J20|rcsb pdb:5J27|rcsb pdb:5J2V|rcsb pdb:5J2X|rcsb pdb:5J64|rcsb pdb:5J6L|rcsb pdb:5J6M|rcsb pdb:5J6N|rcsb pdb:5J80|rcsb pdb:5J82|rcsb pdb:5J86|rcsb pdb:5J8M|rcsb pdb:5J8U|rcsb pdb:5J9X|rcsb pdb:4YKZ|rcsb pdb:5LNY|rcsb pdb:5LNZ|rcsb pdb:5LO0|refseq:NP_001017963.2|refseq:NP_005339.3|dip:DIP-27595N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:qfaAHww82iR1p0hvrJY5oavsNyA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P07737	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P07237	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P07195	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358748|ensembl:ENSP00000229319|ensembl:ENSP00000379386	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ldhb_human(display_long)|uniprotkb:LDHB(gene name)|psi-mi:LDHB(display_short)|uniprotkb:LDH heart subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-46(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001167568.1|refseq:NP_002291.1|refseq:NP_001302466.1|ensembl:ENSG00000111716(gene)|ensembl:ENST00000350669(transcript)|ensembl:ENST00000396076(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P07195|rcsb pdb:1I0Z|rcsb pdb:1T2F|reactome:R-HSA-70268	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:umdj6fjSO7+4SM9Hrl1/K2EiKls9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P06733	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:RmP7cr55H8ylcgBOEyivwljIE+09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P06576	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P06493	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-444308|ensembl:ENSP00000378699|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007569"(cell aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014038"(regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0051301"(cell division)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0042493"|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P06493|rcsb pdb:1LC9|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|go:"GO:0042752"(regulation of circadian rhythm)|rcsb pdb:6GU7|rcsb pdb:6TWN|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P06454	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P05141	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P05023	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358778|uniprotkb:Q16689|uniprotkb:Q6LDM4|uniprotkb:Q9UJ20|uniprotkb:Q9UJ21|uniprotkb:B2RBR6|uniprotkb:Q9UCN1|ensembl:ENSP00000295598|uniprotkb:B7Z3U6|uniprotkb:B7Z2T5|uniprotkb:F5H3A1|intact:EBI-10963133	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:at1a1_human(display_long)|uniprotkb:ATP1A1(gene name)|psi-mi:ATP1A1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000692.2|refseq:NP_001153705.1|refseq:NP_001153706.1|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|ensembl:ENSG00000163399(gene)|ensembl:ENST00000295598(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060342"(photoreceptor inner segment membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903416"(response to glycoside)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P05023|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|refseq:XP_016856849.1|refseq:XP_016856850.1|dip:DIP-38196N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:uZf9iX38kcZh0Q+apz8uB17EtJw9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P04844	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001129243.1|refseq:NP_002942.2|ensembl:ENSG00000118705(gene)|ensembl:ENST00000237530(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007568"(aging)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042493"|go:"GO:0043022"(ribosome binding)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001311234.1|refseq:NP_001311235.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P04843	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P04406	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P04350	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355007|uniprotkb:B3KQP4|uniprotkb:Q969E5|ensembl:ENSP00000264071	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tbb4a_human(display_long)|uniprotkb:TUBB4A(gene name)|psi-mi:TUBB4A(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:Tubulin 5 beta(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006078.2|ensembl:ENSG00000104833(gene)|ensembl:ENST00000264071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0033269"(internode region of axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P04350|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001276052.1|refseq:NP_001276056.1|refseq:NP_001276058.1|refseq:NP_001276059.1|refseq:NP_001276060.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:mMveBNZkQs2x0dyHm/ghVWBe4/49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P04181	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-721662|uniprotkb:Q68CS0|uniprotkb:Q16068|uniprotkb:Q16069|uniprotkb:Q9UD03|intact:EBI-1237002|uniprotkb:Q6IAV9|uniprotkb:D3DRF0|ensembl:ENSP00000357838	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:oat_human(display_long)|uniprotkb:Ornithine--oxo-acid aminotransferase(gene name synonym)|uniprotkb:OAT(gene name)|psi-mi:OAT(display_short)|uniprotkb:Ornithine delta-aminotransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000265.1|refseq:NP_001165285.1|refseq:NP_001309894.1|refseq:NP_001309895.1|refseq:NP_001309896.1|refseq:NP_001309897.1|refseq:NP_001309898.1|refseq:NP_001309899.1|refseq:NP_001309900.1|rcsb pdb:6OIA|rcsb pdb:6V8C|rcsb pdb:6V8D|rcsb pdb:7JX9|reactome:R-HSA-8964539|ensembl:ENSG00000065154(gene)|ensembl:ENST00000368845(transcript)|go:"GO:0004587"(ornithine-oxo-acid transaminase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007601"(visual perception)|go:"GO:0010121"(arginine catabolic process to proline via ornithine)|go:"GO:0019544"(arginine catabolic process to glutamate)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0050155"("ornithine(lysine) transaminase activity")|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR005814(Aminotransferase class-III)|interpro:IPR010164(Ornithine aminotransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|rcsb pdb:1GBN|rcsb pdb:1OAT|rcsb pdb:2BYJ|rcsb pdb:2BYL|rcsb pdb:2CAN|rcsb pdb:2OAT|rcsb pdb:5VWO|rcsb pdb:6HX7	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:j+e5fOgz5Yv7lLp2NV8Uq+eR6909606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P04075	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P00558	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000282.1|dip:DIP-33679N|ensembl:ENSG00000102144(gene)|ensembl:ENST00000373316(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P00492	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-748210|uniprotkb:A6NHF0|uniprotkb:B2R8M9|ensembl:ENSP00000298556	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hprt_human(display_long)|uniprotkb:HPRT1(gene name)|psi-mi:HPRT1(display_short)|uniprotkb:HPRT(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_000185.1|ensembl:ENSG00000165704(gene)|ensembl:ENST00000298556(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001913"(T cell mediated cytotoxicity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004422"(hypoxanthine phosphoribosyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006168"(adenine salvage)|go:"GO:0006178"(guanine salvage)|go:"GO:0007625"(grooming behavior)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021756"(striatum development)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0032263"(GMP salvage)|go:"GO:0032264"(IMP salvage)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043103"(hypoxanthine salvage)|go:"GO:0045964"(positive regulation of dopamine metabolic process)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046100"(hypoxanthine metabolic process)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0052657"(guanine phosphoribosyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR005904(Hypoxanthine phosphoribosyl transferase)|interpro:IPR029057|mint:P00492|rcsb pdb:1BZY|rcsb pdb:1D6N|rcsb pdb:1HMP|rcsb pdb:1Z7G|go:"GO:0048813"(dendrite morphogenesis)|rcsb pdb:2VFA|rcsb pdb:3GEP|rcsb pdb:3GGC|rcsb pdb:3GGJ|rcsb pdb:4IJQ|rcsb pdb:4KN6|rcsb pdb:4RAB|rcsb pdb:4RAC|rcsb pdb:4RAD|rcsb pdb:4RAN|rcsb pdb:4RAO|rcsb pdb:4RAQ|rcsb pdb:5BRN|rcsb pdb:5BSK|rcsb pdb:5HIA|rcsb pdb:5W8V|rcsb pdb:6BNJ|reactome:R-HSA-74217	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:w87Sv/qOAkHFqJm0vu0Ayqlz7TA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P00338	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95861	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1055095|uniprotkb:Q8WVL5|uniprotkb:Q9UGJ3|uniprotkb:A8K7C8|uniprotkb:D3DTA9|uniprotkb:B4DPS5|uniprotkb:B4DUS9|ensembl:ENSP00000318852|ensembl:ENSP00000446828	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:bpnt1_human(display_long)|uniprotkb:Bisphosphate 3'-nucleotidase 1(gene name synonym)|uniprotkb:BPNT1(gene name)|psi-mi:BPNT1(display_short)|uniprotkb:PAP-inositol 1,4-phosphatase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006076.4|refseq:NP_001273078.1|refseq:NP_001273079.1|refseq:XP_005273057.1|refseq:NP_001273080.1|ensembl:ENSG00000162813(gene)|ensembl:ENST00000322067(transcript)|ensembl:ENST00000469520(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008441"("3'(2'),5'-bisphosphate nucleotidase activity")|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|interpro:IPR000760(Inositol monophosphatase)|interpro:IPR020550|interpro:IPR020583|rcsb pdb:2WEF|reactome:R-HSA-156584|refseq:XP_016855532.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:sMaU5Z6Qy2J2O7bTcoR3gRyHNik9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95831	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356440|uniprotkb:Q5JUZ7|uniprotkb:Q6I9X6|uniprotkb:Q9Y3I3|uniprotkb:Q9Y3I4|uniprotkb:A4QPB4|uniprotkb:B1ALN1|uniprotkb:B2RB08|intact:EBI-2561858|uniprotkb:D3DTE9|uniprotkb:Q1L6K6|uniprotkb:Q2QKE4|uniprotkb:Q1L6K4|ensembl:ENSP00000287295|uniprotkb:E9PRR0	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:aifm1_human(display_long)|uniprotkb:AIFM1(gene name)|psi-mi:AIFM1(display_short)|uniprotkb:AIF(gene name synonym)|uniprotkb:PDCD8(gene name synonym)|uniprotkb:Programmed cell death protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001124319.1|refseq:NP_004199.1|refseq:NP_665811.1|refseq:NP_001124318.2|rcsb pdb:5FS6|rcsb pdb:5FS7|rcsb pdb:5FS8|rcsb pdb:5FS9|rcsb pdb:5KVH|rcsb pdb:5KVI|ensembl:ENSG00000156709(gene)|ensembl:ENST00000287295(transcript)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016174"("NAD(P)H oxidase H2O2-forming activity")|go:"GO:0016651"("oxidoreductase activity, acting on NAD(P)H")|go:"GO:0030182"(neuron differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0071949"(FAD binding)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902510"(regulation of apoptotic DNA fragmentation)|go:"GO:1904045"(cellular response to aldosterone)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR023753|interpro:IPR029324|interpro:IPR036188|mint:O95831|rcsb pdb:1M6I|rcsb pdb:4BUR|rcsb pdb:4BV6|rcsb pdb:4FDC|rcsb pdb:4LII|rcsb pdb:5FMH|dip:DIP-32975N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:tAY+mPStfDGbCN4OpvHF4ljQ69I9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95816	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95551	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2819865|uniprotkb:B4DKL8|uniprotkb:Q9NYY9|uniprotkb:Q5JYM0|uniprotkb:Q7Z6U5|uniprotkb:Q2TBE2|uniprotkb:B4DQ95|uniprotkb:Q9NUK5|ensembl:ENSP00000367440	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tydp2_human(display_long)|uniprotkb:TDP2(gene name)|psi-mi:TDP2(display_short)|uniprotkb:EAP2(gene name synonym)|uniprotkb:TTRAP(gene name synonym)|uniprotkb:5'-tyrosyl-DNA phosphodiesterase(gene name synonym)|uniprotkb:ETS1-associated protein 2(gene name synonym)|uniprotkb:ETS1-associated protein II(gene name synonym)|uniprotkb:TRAF and TNF receptor-associated protein(gene name synonym)|uniprotkb:Tyrosyl-RNA phosphodiesterase(gene name synonym)|uniprotkb:VPg unlinkase(gene name synonym)|uniprotkb:AD-022(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_057698.2|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0036317"(tyrosyl-RNA phosphodiesterase activity)|go:"GO:0048666"(neuron development)|go:"GO:0070260"(5'-tyrosyl-DNA phosphodiesterase activity)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR009060(UBA-like)|interpro:IPR036691|rcsb pdb:5INO|rcsb pdb:5J3P|rcsb pdb:5J3S|rcsb pdb:6Q00|rcsb pdb:6Q01|reactome:R-HSA-5693571|ensembl:ENSG00000111802(gene)|ensembl:ENST00000378198(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007166"(cell surface receptor signaling pathway)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Nmd4BuJo8gn2bbTzCXx5P3yj+VM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95433	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-448610|uniprotkb:Q9P060|uniprotkb:Q96IL6|uniprotkb:B2R9L2|uniprotkb:B4DUR9|ensembl:ENSP00000216479	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ahsa1_human(display_long)|uniprotkb:HSPC322(orf name)|uniprotkb:p38(gene name synonym)|uniprotkb:AHSA1(gene name)|psi-mi:AHSA1(display_short)|uniprotkb:C14orf3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_036243.1|refseq:NP_001308370.1|ensembl:ENSG00000100591(gene)|ensembl:ENST00000216479(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|mint:O95433|rcsb pdb:1X53|rcsb pdb:7DMD|rcsb pdb:7DME|go:"GO:0051879"(Hsp90 protein binding)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:HUgJrOxubEHSPst5ZQNxSC38QvY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95400	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-768015|uniprotkb:Q9ULP2|uniprotkb:B2RDX2|ensembl:ENSP00000304903|ensembl:ENSP00000456935	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cd2b2_human(display_long)|uniprotkb:CD2BP2(gene name)|psi-mi:CD2BP2(display_short)|uniprotkb:KIAA1178(gene name synonym)|uniprotkb:U5 snRNP 52K protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001230575.1|refseq:NP_006101.1|ensembl:ENSG00000169217(gene)|ensembl:ENST00000305596(transcript)|ensembl:ENST00000569466(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR003169(GYF)|interpro:IPR035445|interpro:IPR039905|mint:O95400|rcsb pdb:1GYF|rcsb pdb:1L2Z|rcsb pdb:1SYX|rcsb pdb:4BWS|reactome:R-HSA-72163	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:eE6hXTyt05DhzzofcS/QJmUsLEY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95399	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769832|uniprotkb:Q5H8X7|uniprotkb:Q6UXF6|uniprotkb:Q9UKP7|ensembl:ENSP00000355163	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:uts2_human(display_long)|uniprotkb:UNQ525/PRO1068(orf name)|uniprotkb:Urotensin II(gene name synonym)|uniprotkb:UTS2(gene name)|psi-mi:UTS2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006777.1|refseq:NP_068835.1|refseq:XP_011538839.1|refseq:XP_011538840.1|ensembl:ENST00000361696(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005179"(hormone activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006936"(muscle contraction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0045202"(synapse)|go:"GO:0097746"(blood vessel diameter maintenance)|interpro:IPR001483(Urotensin II)|rcsb pdb:6HVB|rcsb pdb:6HVC|reactome:R-HSA-375276|reactome:R-HSA-416476|ensembl:ENSG00000049247(gene)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:EGHV5udqqQh8aJlsg4We0FR6XIs9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95202	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052895|uniprotkb:Q9UF65|uniprotkb:B4DED2|ensembl:ENSP00000305653	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:letm1_human(display_long)|uniprotkb:Leucine zipper-EF-hand-containing transmembrane protein 1(gene name synonym)|uniprotkb:LETM1(gene name)|psi-mi:LETM1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_036450.1|ensembl:ENSG00000168924(gene)|ensembl:ENST00000302787(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006875"(cellular metal ion homeostasis)|go:"GO:0015369"("calcium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042407"(cristae formation)|go:"GO:0043022"(ribosome binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0099093"(calcium export from the mitochondrion)|go:"GO:1900069"(regulation of cellular hyperosmotic salinity response)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011685(LETM1-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR033122|interpro:IPR044202|reactome:R-HSA-8949215|reactome:R-HSA-9013408	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:mDxqXWqmgCjbaZLz4JqteqjDCik9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95163	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347559|uniprotkb:Q9H327|uniprotkb:Q9UG87|uniprotkb:Q5JSV2|ensembl:ENSP00000363779|ensembl:ENSP00000501893	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:elp1_human(display_long)|uniprotkb:ELP1(gene name)|psi-mi:ELP1(display_short)|uniprotkb:IKAP(gene name synonym)|uniprotkb:IKBKAP(gene name synonym)|uniprotkb:p150(gene name synonym)|uniprotkb:IkappaB kinase complex-associated protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	dip:DIP-27579N|refseq:NP_003631.2|refseq:NP_001305289.1|ensembl:ENSG00000070061(gene)|ensembl:ENST00000374647(transcript)|ensembl:ENST00000675406(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR006849(IKI3)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O95163|rcsb pdb:5CQR|reactome:R-HSA-3214847|go:"GO:0005829"(cytosol)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hl+inV6TcN+DGu9CwE3SitkHiI09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O75937	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1045911|uniprotkb:Q6IBA4|uniprotkb:Q8N4Z5|uniprotkb:Q9P051|uniprotkb:Q9P067|uniprotkb:D3DPM0|uniprotkb:B4DUU4|intact:EBI-28966785|ensembl:ENSP00000263697|ensembl:ENSP00000494062	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:dnjc8_human(display_long)|uniprotkb:Splicing protein spf31(gene name synonym)|uniprotkb:DNAJC8(gene name)|psi-mi:DNAJC8(display_short)|uniprotkb:SPF31(gene name synonym)|uniprotkb:HSPC315(orf name)|uniprotkb:HSPC331(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSP00000263697|ensembl:ENSP00000494062|ensembl:ENSG00000126698(gene)|ensembl:ENSG00000285317(gene)|ensembl:ENST00000263697(transcript)|ensembl:ENST00000645856(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0045171"(intercellular bridge)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR036869|interpro:IPR042858|mint:O75937|reactome:R-HSA-72163|refseq:NP_055095.2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:muJkeaOMc4UXHR4DPNuQeciq7PI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O75390	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-487493|ensembl:ENSP00000342056|uniprotkb:Q71UT9|uniprotkb:Q7KZH0|uniprotkb:Q96FZ8|uniprotkb:Q9BWN8	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cisy_human(display_long)|uniprotkb:CS(gene name)|psi-mi:CS(display_short)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0006101"(citrate metabolic process)|refseq:NP_004068.2|ensembl:ENSG00000062485(gene)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000351328(transcript)|rcsb pdb:5UZQ|rcsb pdb:5UZR|reactome:R-HSA-1268020|reactome:R-HSA-71403|go:"GO:0070062"(extracellular exosome)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR010109(Citrate synthase, eukaryotic)|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR019810|interpro:IPR036969|rcsb pdb:5UZP	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:XKpnEsGOlGRNIAXMk4tTBH2okzo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O60869	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-781301|uniprotkb:Q5T5T2|uniprotkb:Q9UIM1|ensembl:ENSP00000224073	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:edf1_human(display_long)|uniprotkb:Multiprotein-bridging factor 1(gene name synonym)|uniprotkb:EDF1(gene name)|psi-mi:EDF1(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003783.1|refseq:NP_694880.1|refseq:NP_001268227.1|refseq:NP_001268228.1|refseq:NP_001268226.1|ensembl:ENSG00000107223(gene)|ensembl:ENST00000224073(transcript)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007275"(multicellular organism development)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR001387(Helix-turn-helix type 3)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR013729(Multiprotein bridging factor 1, N-terminal)|rcsb pdb:1X57|rcsb pdb:6ZVH	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:FxYP3Kzsj2EOpKQY9cidx3a0FJc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O60749	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O60716	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:HgMvbcDKedE291TIvIOqLFT3srw9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O43852	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1171069|uniprotkb:O60456|uniprotkb:Q6FHB9|uniprotkb:Q96RL3|uniprotkb:Q9NR43|intact:EBI-2554631|uniprotkb:B3KPG9|uniprotkb:D6QS48|uniprotkb:D6QS49|uniprotkb:D6QS50|uniprotkb:D6QS51|uniprotkb:D6QS52|uniprotkb:D6QS53|uniprotkb:D6QS54|uniprotkb:D6QS55|uniprotkb:D6QS56|uniprotkb:D6QS57|uniprotkb:D6QS58|uniprotkb:D6QS59|uniprotkb:F5H1Q9|uniprotkb:F5H879|ensembl:ENSP00000249364	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:calu_human(display_long)|uniprotkb:CALU(gene name)|psi-mi:CALU(display_short)|uniprotkb:Crocalbin(gene name synonym)|uniprotkb:IEF SSP 9302(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001124146.1|refseq:NP_001186602.1|refseq:NP_001210.1|refseq:NP_001186600.1|refseq:NP_001186601.1|ensembl:ENSG00000128595(gene)|ensembl:ENST00000249364(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0016020"(membrane)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0042470"(melanosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR027239|mint:O43852|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8957275|refseq:XP_016868148.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:lgl1dEYzu+XFHq3QJ/w69xg51Ts9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O43837	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-725377|uniprotkb:O95106|uniprotkb:Q5JXS8|uniprotkb:Q9NQ06|uniprotkb:Q9NQ07|uniprotkb:Q9UEX0|uniprotkb:Q9UG99|uniprotkb:B2RDR1|uniprotkb:D3DVX2|uniprotkb:D3DVX3|uniprotkb:Q9NUZ0|ensembl:ENSP00000370223	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:idh3b_human(display_long)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)|uniprotkb:IDH3B(gene name)|psi-mi:IDH3B(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_008830.2|refseq:NP_777280.1|ensembl:ENSG00000101365(gene)|ensembl:ENST00000380843(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:O43837|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:7CE3|reactome:R-HSA-71403|refseq:NP_001317692.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:in3sFQUqN4ZtqBii7BotVro104A9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O43765	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347996|ensembl:ENSP00000221566|ensembl:ENSP00000503397|ensembl:ENSP00000504495|uniprotkb:Q9BTZ9|intact:EBI-1045243|uniprotkb:Q6FIA9|uniprotkb:D6W610	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sgta_human(display_long)|uniprotkb:SGTA(gene name)|psi-mi:SGTA(display_short)|uniprotkb:SGT(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym)|uniprotkb:Vpu-binding protein(gene name synonym)|uniprotkb:SGT1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	rcsb pdb:4CPG|rcsb pdb:4GOD|rcsb pdb:4GOE|rcsb pdb:4GOF|reactome:R-HSA-9609523|rcsb pdb:2VYI|ensembl:ENSG00000104969(gene)|ensembl:ENST00000221566(transcript)|ensembl:ENST00000676943(transcript)|ensembl:ENST00000677149(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:O43765|refseq:XP_011526480.1|refseq:NP_003012.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:r/Cyj4UJk/cS8QdrbjhTZMPCigI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O43681	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2515857|ensembl:ENSP00000349887|ensembl:ENSP00000466379|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000198356(gene)|ensembl:ENST00000357332(transcript)|ensembl:ENST00000591090(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|reactome:R-HSA-9609523|refseq:NP_004308.2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O43175	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O15355	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-725702|ensembl:ENSP00000342778	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C,  manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O15067	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1052653|uniprotkb:A6H8V8|ensembl:ENSP00000313490	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pur4_human(display_long)|uniprotkb:Formylglycinamide ribotide amidotransferase(gene name synonym)|uniprotkb:PFAS(gene name)|psi-mi:PFAS(display_short)|uniprotkb:KIAA0361(gene name synonym)|uniprotkb:Formylglycinamide ribonucleotide amidotransferase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_036525.1|ensembl:ENSG00000178921(gene)|ensembl:ENST00000314666(transcript)|go:"GO:0004642"(phosphoribosylformylglycinamidine synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0042493"|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097065"(anterior head development)|interpro:IPR010073(Phosphoribosylformylglycinamidine synthase, eukaryotes and proteobacteria)|interpro:IPR010918(AIR synthase related protein, C-terminal)|interpro:IPR029062|interpro:IPR036604|interpro:IPR036676|interpro:IPR036921|interpro:IPR040707|interpro:IPR041609|mint:O15067|reactome:R-HSA-73817	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:e52AyHjHUrLjnoJP+rInkcvfGJk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O14737	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-712290|ensembl:ENSP00000466214|uniprotkb:Q53YC9|uniprotkb:Q6IB70|uniprotkb:B4DE64	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pdcd5_human(display_long)|uniprotkb:TF-1 cell apoptosis-related protein 19(gene name synonym)|uniprotkb:PDCD5(gene name)|psi-mi:PDCD5(display_short)|uniprotkb:TFAR19(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:1903638"(positive regulation of protein insertion into mitochondrial outer membrane)|go:"GO:1903645"(negative regulation of chaperone-mediated protein folding)|mint:O14737|rcsb pdb:1YYB|rcsb pdb:2CRU|rcsb pdb:2K6B|interpro:IPR002836(DNA-binding TFAR19-related protein)|interpro:IPR036883|ensembl:ENSG00000105185(gene)|ensembl:ENST00000590247(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008201"(heparin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_004699.1|refseq:XP_005259449.1|dip:DIP-50602N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:K2DZzTWT7H8gGATfyR72aXDu5qc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O00483	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O00410	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O00299	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347404|uniprotkb:Q15089|uniprotkb:Q502X1|ensembl:ENSP00000404037|ensembl:ENSP00000404589|ensembl:ENSP00000406088|ensembl:ENSP00000406335|ensembl:ENSP00000406968|ensembl:ENSP00000407429|ensembl:ENSP00000407791|ensembl:ENSP00000408094|ensembl:ENSP00000408357|ensembl:ENSP00000409247|ensembl:ENSP00000409979|ensembl:ENSP00000410965|ensembl:ENSP00000412217|ensembl:ENSP00000413330|ensembl:ENSP00000416211|ensembl:ENSP00000477623|ensembl:ENSP00000478930|ensembl:ENSP00000479501|ensembl:ENSP00000479808|ensembl:ENSP00000480256|ensembl:ENSP00000482255|ensembl:ENSP00000484581|ensembl:ENSP00000364934|ensembl:ENSP00000364935|ensembl:ENSP00000364940|ensembl:ENSP00000372896|ensembl:ENSP00000372897|ensembl:ENSP00000379229|ensembl:ENSP00000382926|ensembl:ENSP00000382931|ensembl:ENSP00000391395|ensembl:ENSP00000398056|ensembl:ENSP00000400280|ensembl:ENSP00000400532|ensembl:ENSP00000401292	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:clic1_human(display_long)|uniprotkb:CLIC1(gene name)|psi-mi:CLIC1(display_short)|uniprotkb:NCC27(gene name synonym)|uniprotkb:Nuclear chloride ion channel 27(gene name synonym)|uniprotkb:Chloride channel ABP(gene name synonym)|uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)|uniprotkb:G6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001279.2|refseq:NP_001274522.1|refseq:NP_001274523.1|ensembl:ENST00000375779(transcript)|ensembl:ENST00000375780(transcript)|ensembl:ENST00000375784(transcript)|ensembl:ENST00000383404(transcript)|ensembl:ENST00000383405(transcript)|ensembl:ENST00000395892(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006821"(chloride transport)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072562"(blood microparticle)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030259|go:"GO:0005634"(nucleus)|ensembl:ENSG00000206394(gene)|ensembl:ENSG00000213719(gene)|ensembl:ENSG00000223639(gene)|ensembl:ENSG00000226248(gene)|ensembl:ENSG00000226417(gene)|ensembl:ENSG00000226651(gene)|ensembl:ENSG00000230685(gene)|ensembl:ENST00000400052(transcript)|ensembl:ENST00000400058(transcript)|ensembl:ENST00000415179(transcript)|ensembl:ENST00000418285(transcript)|ensembl:ENST00000420458(transcript)|ensembl:ENST00000422167(transcript)|ensembl:ENST00000423055(transcript)|ensembl:ENST00000423143(transcript)|ensembl:ENST00000423804(transcript)|ensembl:ENST00000425464(transcript)|ensembl:ENST00000431921(transcript)|ensembl:ENST00000433916(transcript)|ensembl:ENST00000434202(transcript)|ensembl:ENST00000435242(transcript)|ensembl:ENST00000438708(transcript)|ensembl:ENST00000438750(transcript)|ensembl:ENST00000442045(transcript)|ensembl:ENST00000447338(transcript)|ensembl:ENST00000447369(transcript)|ensembl:ENST00000451546(transcript)|ensembl:ENST00000456863(transcript)|ensembl:ENST00000457485(transcript)|ensembl:ENST00000614673(transcript)|ensembl:ENST00000614982(transcript)|ensembl:ENST00000616760(transcript)|ensembl:ENST00000618288(transcript)|ensembl:ENST00000619727(transcript)|ensembl:ENST00000621055(transcript)|ensembl:ENST00000622613(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036282|interpro:IPR040079|mint:O00299|interpro:IPR036249|rcsb pdb:1K0M|rcsb pdb:1K0N|rcsb pdb:1K0O|rcsb pdb:1RK4|rcsb pdb:3O3T|rcsb pdb:3P8W|rcsb pdb:3P90|rcsb pdb:3QR6|rcsb pdb:3SWL|rcsb pdb:3TGZ|rcsb pdb:3UVH|rcsb pdb:4IQA|rcsb pdb:4JZQ|rcsb pdb:4K0G|rcsb pdb:4K0N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:HVux62IcNdqcPgqmlGlIyZTLpFo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O00154	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-948905|ensembl:ENSP00000367086|uniprotkb:O43703|uniprotkb:Q53Y78|uniprotkb:Q5JYL2|uniprotkb:Q5JYL3|uniprotkb:Q5JYL4|uniprotkb:Q5JYL5|uniprotkb:Q5JYL6|uniprotkb:Q5TGR4|uniprotkb:Q9UJM9|uniprotkb:Q9Y539|uniprotkb:Q9Y540|uniprotkb:A8K0K7|uniprotkb:A8K232|uniprotkb:A8K6B8|uniprotkb:A8K837|uniprotkb:B3KQ12	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:bach_human(display_long)|uniprotkb:Long chain acyl-CoA thioester hydrolase(gene name synonym)|uniprotkb:Acyl-CoA thioesterase 7(gene name synonym)|uniprotkb:CTE-IIa(gene name synonym)|uniprotkb:Brain acyl-CoA hydrolase(gene name synonym)|uniprotkb:BACH(gene name synonym)|uniprotkb:ACOT7(gene name)|psi-mi:ACOT7(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0051792"(medium-chain fatty acid biosynthetic process)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1900535"(palmitic acid biosynthetic process)|interpro:IPR006683(Thioesterase superfamily)|interpro:IPR029069|interpro:IPR033120|interpro:IPR040170|mint:O00154|rcsb pdb:2QQ2|reactome:R-HSA-77289|go:"GO:0047617"(acyl-CoA hydrolase activity)|ensembl:ENSG00000097021(gene)|ensembl:ENST00000377855(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0015937"(coenzyme A biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0036042"(long-chain fatty acyl-CoA binding)|go:"GO:0036114"(medium-chain fatty-acyl-CoA catabolic process)|go:"GO:0036116"(long-chain fatty-acyl-CoA catabolic process)|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_863655.1|refseq:NP_863656.1|refseq:NP_009205.3|refseq:NP_863654.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Tv8nHSqfXMmzZqj71+Gec6+29/s9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P14314	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-716953|uniprotkb:Q96BU9|uniprotkb:Q96D06|uniprotkb:Q9P0W9|uniprotkb:A8K318|ensembl:ENSP00000465461	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:glu2b_human(display_long)|uniprotkb:Glucosidase II subunit beta(gene name synonym)|uniprotkb:Protein kinase C substrate 60.1 kDa protein heavy chain(gene name synonym)|uniprotkb:80K-H protein(gene name synonym)|uniprotkb:PRKCSH(gene name)|psi-mi:PRKCSH(display_short)|uniprotkb:G19P1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001001329.1|refseq:NP_002734.2|refseq:XP_011526433.1|refseq:XP_011526434.1|refseq:NP_001276031.1|ensembl:ENSG00000130175(gene)|ensembl:ENST00000589838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006491"(N-glycan processing)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028146|interpro:IPR036055|interpro:IPR036607|interpro:IPR039794|interpro:IPR044865|mint:P14314|reactome:R-HSA-381426|reactome:R-HSA-532668|reactome:R-HSA-879415|reactome:R-HSA-8957275|reactome:R-HSA-901042|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016882466.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hs2AZthZKK6KVW8Blm1RuZVh1QM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P52565	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-712693|intact:EBI-718039|ensembl:ENSP00000269321|ensembl:ENSP00000441348|ensembl:ENSP00000464205|intact:EBI-2840752|uniprotkb:A8MXW0|uniprotkb:B4DDD3|uniprotkb:B4DUV9|uniprotkb:B2R5X1|uniprotkb:Q6IBM5	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:gdir1_human(display_long)|uniprotkb:Rho-GDI alpha(gene name synonym)|uniprotkb:ARHGDIA(gene name)|psi-mi:ARHGDIA(display_short)|uniprotkb:GDIA1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000141522(gene)|ensembl:ENST00000269321(transcript)|ensembl:ENST00000541078(transcript)|ensembl:ENST00000580685(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071461"(cellular response to redox state)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52565|rcsb pdb:1CC0|rcsb pdb:1FSO|rcsb pdb:1FST|rcsb pdb:1FT0|rcsb pdb:1FT3|rcsb pdb:1HH4|rcsb pdb:1KMT|rcsb pdb:1QVY|rcsb pdb:1RHO|rcsb pdb:2BXW|rcsb pdb:2JHS|rcsb pdb:2JHT|rcsb pdb:2JHU|rcsb pdb:2JHV|rcsb pdb:2JHW|rcsb pdb:2JHX|rcsb pdb:2JHY|rcsb pdb:2JHZ|rcsb pdb:2JI0|rcsb pdb:2N80|reactome:R-HSA-193634|reactome:R-HSA-209563|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013407|reactome:R-HSA-9013408|go:"GO:0005634"(nucleus)|refseq:NP_001172006.1|refseq:NP_001172007.1|refseq:NP_004300.1|refseq:NP_001288169.1|refseq:NP_001288170.1|refseq:NP_001288171.1|refseq:NP_001288172.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:nHmwosTUeo1R72Mp5uHLYdcBofk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y2R9	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1054973|uniprotkb:Q53GD6|uniprotkb:B2R9N5|ensembl:ENSP00000245539	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:rt07_human(display_long)|uniprotkb:bMRP-27a(gene name synonym)|uniprotkb:MRPS7(gene name)|psi-mi:MRPS7(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS7m(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_057055.2|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR023798|interpro:IPR036823|mint:Q9Y2R9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125445(gene)|ensembl:ENST00000245539(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hrz2XVS38Ex1z125QFx/n9oPsys9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P62826	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q99623	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358348|uniprotkb:Q2YDA4|uniprotkb:Q7KYU3|uniprotkb:Q92978|ensembl:ENSP00000441875|uniprotkb:B4DP75	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:phb2_human(display_long)|uniprotkb:BAP(gene name synonym)|uniprotkb:REA(gene name synonym)|uniprotkb:PHB2(gene name)|psi-mi:PHB2(display_short)|uniprotkb:D-prohibitin(gene name synonym)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Repressor of estrogen receptor activity(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001138303.1|ensembl:ENSG00000215021(gene)|ensembl:ENST00000535923(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030424"(axon)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q99623|rcsb pdb:6IQE|reactome:R-HSA-8949664|refseq:NP_001254629.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:h4pib54mBeQgOKCe/hib58LM26w9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O75094	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2622593|uniprotkb:O95804|uniprotkb:Q9UFH5|uniprotkb:A6H8U9|ensembl:ENSP00000430333|uniprotkb:J3KNP3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:slit3_human(display_long)|uniprotkb:KIAA0814(gene name synonym)|uniprotkb:MEGF5(gene name synonym)|uniprotkb:SLIL2(gene name synonym)|uniprotkb:Multiple epidermal growth factor-like domains protein 5(gene name synonym)|uniprotkb:UNQ691/PRO1336(orf name)|uniprotkb:SLIT3(gene name)|psi-mi:SLIT3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_003053.1|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428542|ensembl:ENSG00000184347(gene)|ensembl:ENST00000519560(transcript)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0007411"(axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051414"(response to cortisol)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|refseq:NP_001258875.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Qazwnc23w/tZ8NsF8G3ZLSEF1SE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96CP2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-9394506|ensembl:ENSP00000293981|ensembl:ENSP00000380159	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fwch2_human(display_long)|uniprotkb:FLYWCH2(gene name)|psi-mi:FLYWCH2(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001135971.1|refseq:NP_001135972.1|refseq:NP_612448.1|refseq:XP_005255135.1|ensembl:ENSG00000162076(gene)|ensembl:ENST00000293981(transcript)|ensembl:ENST00000396958(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR029279|interpro:IPR040312	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hFUp5nK4z8ENLRQK2GSYIqTFljg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q6Y7W6	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|uniprotkb:B9EG55|intact:EBI-10969943|uniprotkb:A6H8W4|uniprotkb:E9PBB0|ensembl:ENSP00000362664|ensembl:ENSP00000386537	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001096616.1|refseq:NP_056390.2|refseq:NP_001096617.1|refseq:NP_001096618.1|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007631"(feeding behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043204"(perikaryon)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070064"(proline-rich region binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVL|rcsb pdb:5NVM|mint:Q6Y7W6	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P20674	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-715032|uniprotkb:P30045|intact:EBI-1043629|uniprotkb:Q8TB65|ensembl:ENSP00000317780|ensembl:ENSP00000456386	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:cox5a_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)|uniprotkb:COX5A(gene name)|psi-mi:COX5A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004246.2|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P20674|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178741(gene)|ensembl:ENST00000322347(transcript)|ensembl:ENST00000564811(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:dWvZKYawyJQwN29Mhkm44DXXqhg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P62158	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P35080	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-473138|uniprotkb:Q8WVF9|uniprotkb:Q9HBK2|uniprotkb:B2R4C8|uniprotkb:Q4VBQ4|uniprotkb:D3DNI4|ensembl:ENSP00000239940	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:prof2_human(display_long)|uniprotkb:PFN2(gene name)|psi-mi:PFN2(display_short)|uniprotkb:Profilin II(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_002619.1|refseq:NP_444252.1|ensembl:ENSG00000070087(gene)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010633"(negative regulation of epithelial cell migration)|ensembl:ENST00000239940(transcript)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029891|interpro:IPR036140|mint:P35080|rcsb pdb:1D1J|reactome:R-HSA-376176|reactome:R-HSA-5663220	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:064T9afVEb7WrgJPLVbKByJDUXc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O75534	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-719186|uniprotkb:O94961|uniprotkb:Q5TF04|uniprotkb:Q5TF05|uniprotkb:Q68DI9|uniprotkb:Q9Y2S4|uniprotkb:E9PGZ0|uniprotkb:Q68DF1|intact:EBI-1059183|ensembl:ENSP00000351329|ensembl:ENSP00000432958|uniprotkb:A8K281|uniprotkb:G5E9Q2	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:csde1_human(display_long)|uniprotkb:Protein UNR(gene name synonym)|uniprotkb:N-ras upstream gene protein(gene name synonym)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:D1S155E(gene name synonym)|uniprotkb:KIAA0885(gene name synonym)|uniprotkb:NRU(gene name synonym)|uniprotkb:UNR(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001007554.1|refseq:NP_001123995.1|refseq:NP_001229820.1|refseq:NP_001229821.1|refseq:NP_001229822.1|refseq:NP_009089.4|ensembl:ENSG00000009307(gene)|ensembl:ENST00000358528(transcript)|ensembl:ENST00000534699(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008584"(male gonad development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR019844|interpro:IPR024642|mint:O75534|rcsb pdb:1WFQ|rcsb pdb:1X65|rcsb pdb:2YTV|rcsb pdb:2YTX|rcsb pdb:2YTY|interpro:IPR012340(Nucleic acid-binding, OB-fold)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q16527	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2959737|ensembl:ENSP00000310901|ensembl:ENSP00000450056|uniprotkb:Q93030	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:csrp2_human(display_long)|uniprotkb:CSRP2(gene name)|psi-mi:CSRP2(display_short)|uniprotkb:LMO5(gene name synonym)|uniprotkb:SMLIM(gene name synonym)|uniprotkb:Cysteine-rich protein 2(gene name synonym)|uniprotkb:LIM domain only protein 5(gene name synonym)|uniprotkb:Smooth muscle cell LIM protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001312.1|ensembl:ENSG00000175183(gene)|ensembl:ENST00000311083(transcript)|ensembl:ENST00000546966(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0042805"(actinin binding)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046872"(metal ion binding)|go:"GO:0060537"(muscle tissue development)|interpro:IPR001781(Zinc finger, LIM-type)|refseq:NP_001287894.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:nyQ01E4UJb21IE/mZhZjXakJoyo9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q99733	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2255116|uniprotkb:B2R6J4|uniprotkb:F5HFY4|ensembl:ENSP00000369915|ensembl:ENSP00000483728	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:np1l4_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)|uniprotkb:NAP2(gene name synonym)|uniprotkb:Nucleosome assembly protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005960.1|ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000380542(transcript)|ensembl:ENST00000619695(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q99733	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:tES8IJDlW4JONR/pdC8dq49I/7Y9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9Y277	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-354196|uniprotkb:Q9UIS0|ensembl:ENSP00000022615	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:vdac3_human(display_long)|uniprotkb:VDAC3(gene name)|psi-mi:VDAC3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001129166.1|refseq:NP_005653.3|ensembl:ENSG00000078668(gene)|ensembl:ENST00000022615(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015853"(adenine transport)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030271|mint:Q9Y277|reactome:R-HSA-5689880|reactome:R-HSA-8949215	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:En6g89Dp+C4s1ArGYJyVfUBVsO09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P11586	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-709638|uniprotkb:Q86VC9|uniprotkb:Q9BVP5|uniprotkb:B2R5Y2|uniprotkb:G3V2B8|intact:EBI-21358459|uniprotkb:A0A024R652|uniprotkb:A0A384N5Y3|ensembl:ENSP00000498336|ensembl:ENSP00000498511	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:c1tc_human(display_long)|uniprotkb:MTHFD1(gene name)|psi-mi:MTHFD1(display_short)|uniprotkb:MTHFC(gene name synonym)|uniprotkb:MTHFD(gene name synonym)|uniprotkb:Epididymis secretory sperm binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005947.3|dip:DIP-33682N|ensembl:ENSG00000100714(gene)|ensembl:ENST00000651537(transcript)|ensembl:ENST00000652337(transcript)|go:"GO:0000105"(histidine biosynthetic process)|go:"GO:0001843"(neural tube closure)|go:"GO:0004329"(formate-tetrahydrofolate ligase activity)|go:"GO:0004477"(methenyltetrahydrofolate cyclohydrolase activity)|go:"GO:0004486"("methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity")|go:"GO:0004487"("methylenetetrahydrofolate dehydrogenase (NAD+) activity")|go:"GO:0004488"("methylenetetrahydrofolate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0009069"(serine family amino acid metabolic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0009257"(10-formyltetrahydrofolate biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048703"(embryonic viscerocranium morphogenesis)|go:"GO:0061053"(somite development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000559(Formate-tetrahydrofolate ligase, FTHFS)|interpro:IPR000672(Tetrahydrofolate dehydrogenase/cyclohydrolase)|interpro:IPR020628|interpro:IPR020630|interpro:IPR020631|interpro:IPR020867|interpro:IPR027417|interpro:IPR036291|mint:P11586|rcsb pdb:1A4I|rcsb pdb:1DIA|rcsb pdb:1DIB|rcsb pdb:1DIG|rcsb pdb:6ECP|rcsb pdb:6ECQ|rcsb pdb:6ECR|reactome:R-HSA-196757	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:6ZizfpjVcaL5WNxKXL7qJpw59PI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P63104	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P27816	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-715255|uniprotkb:Q59FT2|uniprotkb:Q68D74|uniprotkb:Q6ZUW9|uniprotkb:Q96NS9|uniprotkb:Q13082|uniprotkb:Q96A76|ensembl:ENSP00000353375|uniprotkb:Q86V26	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:map4_human(display_long)|uniprotkb:MAP4(gene name)|psi-mi:MAP4(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001127836.1|refseq:NP_002366.2|ensembl:ENSG00000047849(gene)|ensembl:ENST00000360240(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27816|refseq:NP_112147.2	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:rBf82W3kFCo+2UklK5WHO3MWjV09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O95757	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P30566	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2511688|ensembl:ENSP00000485525|uniprotkb:B0QY76|uniprotkb:O75495|uniprotkb:Q5TI34	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:pur8_human(display_long)|uniprotkb:ADSL(gene name)|psi-mi:ADSL(display_short)|uniprotkb:AMPS(gene name synonym)|uniprotkb:Adenylosuccinase(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0014850"(response to muscle activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0070626"("(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity")|ensembl:ENSG00000239900(gene)|ensembl:ENST00000623063(transcript)|interpro:IPR000362(Fumarate lyase)|interpro:IPR004769(Adenylosuccinate lyase)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR019468|interpro:IPR020557|interpro:IPR022761|rcsb pdb:2J91|rcsb pdb:2VD6|rcsb pdb:4FFX|rcsb pdb:4FLC|reactome:R-HSA-73817|go:"GO:0001666"(response to hypoxia)|go:"GO:0004018"("N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009060"(aerobic respiration)|refseq:NP_000017.1|refseq:NP_001116850.1|refseq:NP_001304852.1	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:yBhDdHJgZN1NJDpN2ivKLI4oUG09606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:O75347	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-2686341|uniprotkb:B4DT30|ensembl:ENSP00000369736	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:tbca_human(display_long)|uniprotkb:TCP1-chaperonin cofactor A(gene name synonym)|uniprotkb:Tubulin-folding cofactor A(gene name synonym)|uniprotkb:TBCA(gene name)|psi-mi:TBCA(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_004598.1|refseq:NP_001284667.1|ensembl:ENSG00000171530(gene)|ensembl:ENST00000380377(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR004226(Tubulin binding cofactor A)|interpro:IPR036126|mint:O75347|rcsb pdb:1H7C|reactome:R-HSA-389977	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:hETmNl4lTAEyZ89oOKuhkah5vmQ9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P84085	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-4289908|uniprotkb:P26437|ensembl:ENSP00000000233	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:arf5_human(display_long)|uniprotkb:ARF5(gene name)|psi-mi:ARF5(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000004059(gene)|ensembl:ENST00000000233(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84085|rcsb pdb:2B6H|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001653.1|dip:DIP-61289N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P51965-2	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769826|ensembl:ENSP00000411351	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:p51965-2(display_long)|uniprotkb:UbcH6(gene name synonym)|uniprotkb:Ubiquitin carrier protein E1(gene name synonym)|uniprotkb:Ubiquitin-protein ligase E1(gene name synonym)|uniprotkb:"(E3-independent) E2 ubiquitin-conjugating enzyme E1"(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme E1(gene name synonym)|uniprotkb:UBE2E1(gene name)|psi-mi:UBE2E1(display_short)|uniprotkb:UBCH6(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000170142(gene)|ensembl:ENST00000424381(transcript)|intact:EBI-348546(isoform-parent)	-	-	isoform-comment:No experimental confirmation available.	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:icHkQme/OUwgdkhm+4AwQzwo7Gg9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9BWD1	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1047273|uniprotkb:E1P5B1|uniprotkb:Q16146|uniprotkb:Q5TCL7|uniprotkb:Q8TDM4|uniprotkb:B7Z233|ensembl:ENSP00000356015	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:thic_human(display_long)|uniprotkb:Cytosolic acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:Acetyl-CoA transferase-like protein(gene name synonym)|uniprotkb:ACAT2(gene name)|psi-mi:ACAT2(display_short)|uniprotkb:ACTL(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_005882.2|refseq:NP_001290182.1|ensembl:ENSG00000120437(gene)|ensembl:ENST00000367048(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020616|interpro:IPR020617|rcsb pdb:1WL4|rcsb pdb:1WL5|reactome:R-HSA-191273	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:JW66UFxxwRH0wEuVjCyB0MFNZl49606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q92598	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q96AE4	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-711404|uniprotkb:Q12828|ensembl:ENSP00000359804	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:fubp1_human(display_long)|uniprotkb:FUBP1(gene name)|psi-mi:FUBP1(display_short)|uniprotkb:DNA helicase V(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR015096(Region of unknown function DUF1897)|interpro:IPR036612|mint:Q96AE4|rcsb pdb:1J4W|rcsb pdb:2KXH|rcsb pdb:4LIJ|rcsb pdb:6Y24|rcsb pdb:6Y2C|rcsb pdb:6Y2D|ensembl:ENSG00000162613(gene)|ensembl:ENST00000370768(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|refseq:NP_003893.2|refseq:NP_001290362.1|refseq:XP_016858232.1|dip:DIP-47273N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:38IaQgYv8qLMAryXO0lbfzgjjsM9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9H910	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-723928|uniprotkb:B1AJY2|uniprotkb:Q6EIC7|uniprotkb:B4DLH4|ensembl:ENSP00000248098	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:jupi2_human(display_long)|uniprotkb:JPT2(gene name)|psi-mi:JPT2(display_short)|uniprotkb:C16orf34(gene name synonym)|uniprotkb:HN1L(gene name synonym)|uniprotkb:Hematological and neurological expressed 1-like protein(gene name synonym)|uniprotkb:L11(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_653171.1|ensembl:ENSG00000206053(gene)|ensembl:ENST00000248098(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|interpro:IPR033335	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:N6Hzq6qLkultacULcRS03yxq+eE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P27824	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:B3EWF7	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-10769821	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:ep2a2_human(display_long)|uniprotkb:EPM2A(gene name)|psi-mi:EPM2A(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	go:"GO:0005634"(nucleus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0032007"(negative regulation of TOR signaling)	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:xXiFLf6cBEd7MKvD9ljDS8cjtUE9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:P48444	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-1044491|ensembl:ENSP00000264028|uniprotkb:Q52M80|uniprotkb:B4E1X2|uniprotkb:E9PEU4	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:copd_human(display_long)|uniprotkb:Delta-coat protein(gene name synonym)|uniprotkb:ARCN1(gene name)|psi-mi:ARCN1(display_short)|uniprotkb:COPD(gene name synonym)|uniprotkb:Archain(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-10770198|imex:IM-23897-2	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	ensembl:ENSG00000095139(gene)|ensembl:ENST00000264028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0016020"(membrane)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0043473"(pigmentation)|go:"GO:0051645"(Golgi localization)|interpro:IPR011012(Longin-like)|interpro:IPR022775|interpro:IPR027059|interpro:IPR028565|interpro:IPR036168|mint:P48444|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001135753.1|refseq:NP_001646.2|dip:DIP-50375N	-	-	-	figure legend:Table 3, S3 Data set|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2021/06/18	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:67dTqyFC/zHDlTapW36OMyXbz0M9606	rigid:kKTdhGCFZ87QKEhBfTtiei4SD9M	false	flag tag:n-n|mutation:22-22	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q96FW1	uniprotkb:Q9NWT6	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:1000"(hydroxylase assay)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0210"(hydroxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11473640|imex:IM-23897-3	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/26	2016/01/04	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rigid:nQI5xHO4nPW2NrMoGAjB9u2CXKU	false	mutation decreasing interaction rate:22-22|sufficient binding region:7-40	maltose binding protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q16665	uniprotkb:Q9NWT6	intact:EBI-447269|uniprotkb:Q53XP6|uniprotkb:Q96PT9|uniprotkb:Q9UPB1|uniprotkb:C0LZJ3|ensembl:ENSP00000338018	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:hif1a_human(display_long)|uniprotkb:ARNT-interacting protein(gene name synonym)|uniprotkb:Member of PAS protein 1(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP1(gene name synonym)|uniprotkb:HIF1A(gene name)|psi-mi:HIF1A(display_short)|uniprotkb:MOP1(gene name synonym)|uniprotkb:BHLHE78(gene name synonym)|uniprotkb:PASD8(gene name synonym)|uniprotkb:PAS domain-containing protein 8(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 78(gene name synonym)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:1000"(hydroxylase assay)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0210"(hydroxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11473697|imex:IM-23897-4	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001230013.1|refseq:NP_001521.1|refseq:NP_851397.1|ensembl:ENST00000323441|ensembl:ENSP00000323326|ensembl:ENSP00000338018|ensembl:ENST00000539097|ensembl:ENSP00000437955|dip:DIP-29722N|ensembl:ENSG00000100644(gene)|ensembl:ENST00000337138(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001922"(B-1 B cell homeostasis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002248"(connective tissue replacement involved in inflammatory response wound healing)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007165"(signal transduction)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008542"(visual learning)|go:"GO:0010039"(response to iron ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010573"(vascular endothelial growth factor production)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021502"(neural fold elevation formation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031514"(motile cilium)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032909"(regulation of transforming growth factor beta2 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042541"(hemoglobin biosynthetic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048546"(digestive tract morphogenesis)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051216"(cartilage development)|go:"GO:0051541"(elastin metabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0061030"(epithelial cell differentiation involved in mammary gland alveolus development)|go:"GO:0061072"(iris morphogenesis)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0070101"(positive regulation of chemokine-mediated signaling pathway)|go:"GO:0070244"(negative regulation of thymocyte apoptotic process)|go:"GO:0070888"(E-box binding)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097411"(hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:0098586"(cellular response to virus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000434"(regulation of protein neddylation)|go:"GO:2001054"(negative regulation of mesenchymal cell apoptotic process)|interpro:IPR000014(PAS)|interpro:IPR001321(Hypoxia-inducible factor-1 alpha, PAS fold)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q16665|rcsb pdb:1D7G|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1L3E|rcsb pdb:1L8C|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:2ILM|rcsb pdb:3HQR|rcsb pdb:3HQU|rcsb pdb:4AJY|rcsb pdb:4H6J|rcsb pdb:5JWP|rcsb pdb:5L9B|rcsb pdb:5L9V|rcsb pdb:5LA9|rcsb pdb:5LAS|rcsb pdb:6GFX|rcsb pdb:6GMR|rcsb pdb:6YW3|reactome:R-HSA-1234158|reactome:R-HSA-1234174|reactome:R-HSA-1234176|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|reactome:R-HSA-2122947|reactome:R-HSA-400253|reactome:R-HSA-5689880|reactome:R-HSA-6785807|reactome:R-HSA-8849473|reactome:R-HSA-8857538|reactome:R-HSA-8951664	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/26	2016/01/04	rogid:3XRt8HFMCRlxcYR2KfuFSq6gVBg9606	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rigid:TJOLhW2M/U6hGdJbvN/BVF8i+Dc	false	sufficient binding region:788-806	maltose binding protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P46531	uniprotkb:Q9NWT6	intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:1000"(hydroxylase assay)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0210"(hydroxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11473706|imex:IM-23897-5	-	-	psi-mi:"MI:0502"(enzyme target)	psi-mi:"MI:0501"(enzyme)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060087.3|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006955"(immune response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0005912"(adherens junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007411"(axon guidance)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021515"(cell differentiation in spinal cord)|go:"GO:0021915"(neural tube development)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035148"(tube formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060768"(regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060843"(venous endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2000974"(negative regulation of pro-B cell differentiation)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|go:"GO:0070986"(left/right axis specification)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022362|interpro:IPR024600|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|interpro:IPR035993|interpro:IPR036770|mint:P46531|rcsb pdb:1PB5|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000148400(gene)|ensembl:ENST00000651671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003182"(coronary sinus valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003192"(mitral valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003241"(growth involved in heart morphogenesis)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003270"(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0003332"(negative regulation of extracellular matrix constituent secretion)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|dip:DIP-29919N|ensembl:ENSP00000498587	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:Fig. 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2015/02/26	2016/01/04	rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rigid:g6U+4tSORADC0yLDYpOC+E4UiBg	false	sufficient binding region:2007-2026	maltose binding protein tag:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96FW1	uniprotkb:Q9NWT6	intact:EBI-1058491|uniprotkb:Q32Q78|uniprotkb:Q96II3|uniprotkb:Q9NXQ4|uniprotkb:Q9P0B8|ensembl:ENSP00000402551|ensembl:ENSP00000444357	intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69	psi-mi:otub1_human(display_long)|uniprotkb:OTUB1(gene name)|psi-mi:OTUB1(display_short)|uniprotkb:OTB1(gene name synonym)|uniprotkb:OTU1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:HSPC263(orf name)	psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Scholz et al. (2016)	imex:IM-23897|pubmed:26752685	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0210"(hydroxylation reaction)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11473738|imex:IM-23897-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060140.2|ensembl:ENSG00000167770(gene)|ensembl:ENST00000428192(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENST00000538426(transcript)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:Q96FW1|rcsb pdb:2ZFY|rcsb pdb:3VON|rcsb pdb:4DDG|rcsb pdb:4DDI|rcsb pdb:4DHZ|rcsb pdb:4I6L|rcsb pdb:4LDT|reactome:R-HSA-5689880|reactome:R-HSA-5689896|dip:DIP-41158N	refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N	-	-	-	figure legend:Fig. 4C, Supp. Fig. 5G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2015/02/26	2016/01/04	rogid:jD7ZA6L1tq8K8LO70w2RnGhZv349606	rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606	rigid:nQI5xHO4nPW2NrMoGAjB9u2CXKU	false	mutation disrupting interaction strength:22-22|flag tag:n-n	v5 tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)