#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-2213511	uniprotkb:P30822	rnacentral:URS0000348061_559292	intact:EBI-20589|uniprotkb:D6VV01|ensemblfungi:YGR218W	psi-mi:tlc1_yeast_rna(display_short)|psi-mi:EBI-2213511(display_long)	psi-mi:xpo1_yeast(display_long)|uniprotkb:CRM1(gene name)|psi-mi:CRM1(display_short)|uniprotkb:KAP124(gene name synonym)|uniprotkb:YGR218W(locus name)|uniprotkb:G8514(orf name)|uniprotkb:XPO1(gene name synonym)|uniprotkb:Chromosome region maintenance protein 1(gene name synonym)|uniprotkb:Karyopherin-124(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2014)	imex:IM-24863|pubmed:25220466	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11360525|imex:IM-24863-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	sgd:S000006657(see-also)	refseq:NP_011734.3|sgd:S000003450|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051168"(nuclear export)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR014877(Exportin 1, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040485|interpro:IPR041123|interpro:IPR041235|rcsb pdb:3M1I|rcsb pdb:3VYC|rcsb pdb:3WYF|rcsb pdb:3WYG|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5XOJ|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7L5E|reactome:R-SCE-5687128|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|ensemblfungi:YGR218W(gene)|ensemblfungi:YGR218W_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000776"(kinetochore)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005816"(spindle pole body)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|dip:DIP-2244N|mint:P30822	-	comment:"TLC1 RNA contains a template sequence that Est2p uses to add irregular repeats of TG(1-3) residues onto a DNA end; RNA template component of telomerase"	crc64:A81833C7F60F5202	figure legend:Fig1 D, Fig2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/11/03	2016/03/18	-	rogid:9YWJL+G+yiF+OkUyDF3VTfDYLag559292	-	false	-	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:1196"(quantitative reverse transcription pcr)	psi-mi:"MI:1196"(quantitative reverse transcription pcr)
uniprotkb:Q06163	intact:EBI-2213511	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	rnacentral:URS0000348061_559292	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:tlc1_yeast_rna(display_short)|psi-mi:EBI-2213511(display_long)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2014)	imex:IM-24863|pubmed:25220466	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11360531|imex:IM-24863-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0320"(ribonucleic acid)	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	sgd:S000006657(see-also)	-	crc64:84540735E3CD40F5	comment:"TLC1 RNA contains a template sequence that Est2p uses to add irregular repeats of TG(1-3) residues onto a DNA end; RNA template component of telomerase"	figure legend:Fig1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/11/03	2016/03/18	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	-	-	false	myc tag:n-n	-	-	-	psi-mi:"MI:1196"(quantitative reverse transcription pcr)	psi-mi:"MI:1196"(quantitative reverse transcription pcr)
uniprotkb:Q06163	uniprotkb:P17214	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2014)	imex:IM-24863|pubmed:25220466	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11360531|imex:IM-24863-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458	-	crc64:84540735E3CD40F5	crc64:9CF552AFDA6BDEDE	figure legend:Fig1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/11/03	2016/03/18	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	-	false	myc tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:1196"(quantitative reverse transcription pcr)	psi-mi:"MI:1196"(quantitative reverse transcription pcr)
intact:EBI-2213511	uniprotkb:Q99257	rnacentral:URS0000348061_559292	intact:EBI-11642|ensemblfungi:YPL169C|uniprotkb:D6W3J9	psi-mi:tlc1_yeast_rna(display_short)|psi-mi:EBI-2213511(display_long)	psi-mi:mex67_yeast(display_long)|uniprotkb:MEX67(gene name)|psi-mi:MEX67(display_short)|uniprotkb:P2520(orf name)|uniprotkb:YPL169C(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2014)	imex:IM-24863|pubmed:25220466	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11360537|imex:IM-24863-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	sgd:S000006657(see-also)	ensemblfungi:YPL169C(gene)|ensemblfungi:YPL169C_mRNA(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0006406"(mRNA export from nucleus)|interpro:IPR032710|interpro:IPR040736|go:"GO:0015288"(porin activity)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|rcsb pdb:1OF5|rcsb pdb:2JP7|rcsb pdb:2KHH|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:4WWU|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030623"(U5 snRNA binding)|go:"GO:0042272"(nuclear RNA export factor complex)|go:"GO:0051168"(nuclear export)|rcsb pdb:6EXZ|go:"GO:0055085"(transmembrane transport)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR005637(TAP, C-terminal)|interpro:IPR009060(UBA-like)|interpro:IPR018222|interpro:IPR030217|interpro:IPR032675|refseq:NP_015156.1|sgd:S000006090|mint:Q99257|dip:DIP-3984N	-	comment:"TLC1 RNA contains a template sequence that Est2p uses to add irregular repeats of TG(1-3) residues onto a DNA end; RNA template component of telomerase"	crc64:6CE55EEC6FA40B40	figure legend:Fig1D, Fig2D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/11/03	2016/03/18	-	rogid:nIu6N+mnZtRkH8psmpu1AyfB5uo559292	-	false	-	green fluorescent protein tag:c-c|mutation increasing interaction:400-400	-	-	psi-mi:"MI:1196"(quantitative reverse transcription pcr)	psi-mi:"MI:1196"(quantitative reverse transcription pcr)
intact:EBI-2213511	uniprotkb:P20449	rnacentral:URS0000348061_559292	intact:EBI-5617|uniprotkb:D6W2B2|ensemblfungi:YOR046C	psi-mi:tlc1_yeast_rna(display_short)|psi-mi:EBI-2213511(display_long)	psi-mi:dbp5_yeast(display_long)|uniprotkb:YOR046C(locus name)|uniprotkb:DBP5(gene name)|psi-mi:DBP5(display_short)|uniprotkb:RAT8(gene name synonym)|uniprotkb:DEAD box protein 5(gene name synonym)|uniprotkb:Helicase CA5/6(gene name synonym)|uniprotkb:Ribonucleic acid-trafficking protein 8(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2014)	imex:IM-24863|pubmed:25220466	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11360546|imex:IM-24863-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	sgd:S000006657(see-also)	refseq:NP_014689.1|sgd:S000005572|dip:DIP-2352N|mint:P20449|ensemblfungi:YOR046C(gene)|ensemblfungi:YOR046C_mRNA(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005844"(polysome)|go:"GO:0005934"(cellular bud tip)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0006415"(translational termination)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0015031"(protein transport)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0031965"(nuclear membrane)|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|rcsb pdb:2KBE|rcsb pdb:2KBF|rcsb pdb:3GFP|rcsb pdb:3PEU|rcsb pdb:3PEV|rcsb pdb:3PEW|rcsb pdb:3PEY|rcsb pdb:3RRM|rcsb pdb:3RRN|rcsb pdb:5ELX	-	comment:"TLC1 RNA contains a template sequence that Est2p uses to add irregular repeats of TG(1-3) residues onto a DNA end; RNA template component of telomerase"	crc64:C50CAFE8C060D46B	figure legend:Fig1D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/11/03	2016/03/18	-	rogid:54iW7iCC7GTFWfgoHUq0Qv5WVMI559292	-	false	-	myc tag:n-n	-	-	psi-mi:"MI:1196"(quantitative reverse transcription pcr)	psi-mi:"MI:1196"(quantitative reverse transcription pcr)
intact:EBI-2213511	uniprotkb:Q06163	rnacentral:URS0000348061_559292	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	psi-mi:tlc1_yeast_rna(display_short)|psi-mi:EBI-2213511(display_long)	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2014)	imex:IM-24863|pubmed:25220466	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11360555|imex:IM-24863-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0320"(ribonucleic acid)	psi-mi:"MI:0326"(protein)	sgd:S000006657(see-also)	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	-	comment:"TLC1 RNA contains a template sequence that Est2p uses to add irregular repeats of TG(1-3) residues onto a DNA end; RNA template component of telomerase"	crc64:84540735E3CD40F5	figure legend:Fig3D|comment:mutations in Xpo1, Rat7, Rat8 and mex67 diminish the binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/11/03	2016/03/18	-	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	-	false	-	flag tag:n-n|myc tag:n-n	-	-	psi-mi:"MI:1196"(quantitative reverse transcription pcr)	psi-mi:"MI:1196"(quantitative reverse transcription pcr)
uniprotkb:Q06163	uniprotkb:P17214	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	intact:EBI-6684|uniprotkb:Q05997|uniprotkb:D6VYN3|ensemblfungi:YLR233C	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:est1_yeast(display_long)|uniprotkb:EST1(gene name)|psi-mi:EST1(display_short)|uniprotkb:YLR233C(locus name)|uniprotkb:L8083.15(orf name)|uniprotkb:Ever shorter telomeres protein 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2014)	imex:IM-24863|pubmed:25220466	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11360564|imex:IM-24863-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	refseq:NP_013334.1|sgd:S000004223|reactome:R-SCE-975957|dip:DIP-1306N|ensemblfungi:YLR233C(gene)|ensemblfungi:YLR233C_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458	-	crc64:84540735E3CD40F5	crc64:9CF552AFDA6BDEDE	figure legend:Fig3 E|comment:The deletion of Tlc1 diminishes the binding|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/11/03	2015/11/03	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	rogid:hu3SMHhlU1yKF9bVHdYQucREmxQ559292	rigid:7ICUyvNvL1+v1TwuqWnpCpYVU3c	false	flag tag:n-n|myc tag:n-n	myc tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q06163	uniprotkb:P32807	intact:EBI-3764464|uniprotkb:D6VYW1|ensemblfungi:YLR318W	intact:EBI-8214|uniprotkb:P32498|uniprotkb:Q0P778|uniprotkb:Q0P779|uniprotkb:Q0P787|uniprotkb:Q0P789|uniprotkb:Q6B267|uniprotkb:D6W0B1|ensemblfungi:YMR284W	psi-mi:tert_yeast(display_long)|uniprotkb:EST2(gene name)|psi-mi:EST2(display_short)|uniprotkb:Telomerase catalytic subunit(gene name synonym)|uniprotkb:L8543.12(orf name)|uniprotkb:YLR318W(locus name)	psi-mi:ku70_yeast(display_long)|uniprotkb:YKU70(gene name)|psi-mi:YKU70(display_short)|uniprotkb:HDF1(gene name synonym)|uniprotkb:NES24(gene name synonym)|uniprotkb:YMR284W(locus name)|uniprotkb:YM8021.10(orf name)|uniprotkb:ATP-dependent DNA helicase II subunit Ku70(gene name synonym)|uniprotkb:High affinity DNA-binding factor subunit 1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Wu et al. (2014)	imex:IM-24863|pubmed:25220466	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-11360575|imex:IM-24863-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_013422.2|sgd:S000004310|dip:DIP-7548N|ensemblfungi:YLR318W(gene)|ensemblfungi:YLR318W_mRNA(transcript)|go:"GO:0000333"(telomerase catalytic core complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003721"(telomerase RNA reverse transcriptase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070034"(telomerase RNA binding)|interpro:IPR000477("RNA-directed DNA polymerase (reverse transcriptase)")|interpro:IPR003545(Telomere reverse transcriptase)|interpro:IPR021891	refseq:NP_014011.1|sgd:S000004897|mint:P32807|dip:DIP-2483N|ensemblfungi:YMR284W(gene)|ensemblfungi:YMR284W_mRNA(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006348"|go:"GO:0030466"(silent mating-type cassette heterochromatin assembly)|go:"GO:0031509"(subtelomeric heterochromatin assembly)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0097695"(establishment of protein-containing complex localization to telomere)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR036465|rcsb pdb:5Y58|reactome:R-SCE-6798695	-	crc64:84540735E3CD40F5	crc64:BD58160328EE6C6E	figure legend:Fig3G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2015/11/03	2015/11/03	rogid:DaX8x7PaQFAD7ZXlPC+8C7/N3uY559292	rogid:AKKL1fZRRRRdvp9vExDLfMo/u6o559292	rigid:9vSaj+r1rfgdZgEvbg45Gm/X6qo	false	flag tag:n-n|myc tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)