#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P46116 uniprotkb:A1YH68 intact:EBI-10098058 intact:EBI-10098044|ensemblbacteria:SUC45241|ensemblbacteria:SUC77857 psi-mi:aara_prost(display_long)|uniprotkb:aarA(gene name)|psi-mi:aarA(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym) psi-mi:a1yh68_prost(display_long)|uniprotkb:tatA(gene name)|psi-mi:tatA(display_short)|uniprotkb:NCTC12257_03922(orf name) psi-mi:"MI:0415"(enzymatic study) Arutyunova et al. (2014) imex:IM-23751|pubmed:25009246 taxid:588(prost)|taxid:588(Providencia stuartii) taxid:588(prost)|taxid:588(Providencia stuartii) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-10098056|imex:IM-23751-1 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_004917931.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022764|interpro:IPR035952|dip:DIP-60798N refseq:WP_004924718.1|ensemblbacteria:NCTC11800_03651(gene)|ensemblbacteria:NCTC12257_03922(gene)|ensemblbacteria:SUC45241(transcript)|ensemblbacteria:SUC77857(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0033281"(TAT protein transport complex)|go:"GO:0043953"(protein transport by the Tat complex)|interpro:IPR003369(Bacterial sec-independent translocation protein mttA/Hcf106)|interpro:IPR006312(Twin-arginine translocation protein TatA/E)|dip:DIP-60799N - - - figure legend:f1b f1c t1 sf1 f4f sf4a|comment:For all three rhomboids, we observed a loss of activity in the presence of DM, at conditions where the protein exists as a monomer. For AarA, purified in DDM, only 50% of activity was observed in DM reaction buffer, consistent with the gel filtration results, showing only partial dissociation. A full loss of activity for AarA was observed only when DM was used in both Ni-NTA purification and the activity assay.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/29 2015/01/29 rogid:rMLMMVi9OcU6ksCBsNOREGL4uPA588 rogid:PkODM+LJUIm2icak0UjYA99sezc588 intact-crc:87543385D45F054F|rigid:/+Vemi0U1dJHjv9zZkP55kBw0dA false - - 2 - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:A1YH68 uniprotkb:P44783 intact:EBI-10098044|ensemblbacteria:SUC45241|ensemblbacteria:SUC77857 intact:EBI-10098079|ensemblbacteria:AAC22277 psi-mi:a1yh68_prost(display_long)|uniprotkb:tatA(gene name)|psi-mi:tatA(display_short)|uniprotkb:NCTC12257_03922(orf name) psi-mi:glpg_haein(display_long)|uniprotkb:glpG(gene name)|psi-mi:glpG(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym)|uniprotkb:HI_0618(locus name) psi-mi:"MI:0415"(enzymatic study) Arutyunova et al. (2014) imex:IM-23751|pubmed:25009246 taxid:588(prost)|taxid:588(Providencia stuartii) taxid:71421(haein)|taxid:71421(Haemophilus influenzae) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-10098075|imex:IM-23751-3 - - psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_004924718.1|ensemblbacteria:NCTC11800_03651(gene)|ensemblbacteria:NCTC12257_03922(gene)|ensemblbacteria:SUC45241(transcript)|ensemblbacteria:SUC77857(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0033281"(TAT protein transport complex)|go:"GO:0043953"(protein transport by the Tat complex)|interpro:IPR003369(Bacterial sec-independent translocation protein mttA/Hcf106)|interpro:IPR006312(Twin-arginine translocation protein TatA/E)|dip:DIP-60799N interpro:IPR022764|rcsb pdb:2NR9|rcsb pdb:3ODJ|refseq:NP_438776.1|interpro:IPR035952|refseq:WP_005648561.1|ensemblbacteria:AAC22277(transcript)|ensemblbacteria:HI_0618(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) - - - figure legend:f1b f1c t1 f4d sf4c|comment:For all three rhomboids, we observed a loss of activity in the presence of DM, at conditions where the protein exists as a monomer. For AarA, purified in DDM, only 50% of activity was observed in DM reaction buffer, consistent with the gel filtration results, showing only partial dissociation. A full loss of activity for AarA was observed only when DM was used in both Ni-NTA purification and the activity assay.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/29 2015/01/29 rogid:PkODM+LJUIm2icak0UjYA99sezc588 rogid:5L9JHN5FCD3YnHhk9cGMFtjt9pQ71421 intact-crc:73495BF2EE52C5AC|rigid:kxrkNOjSIzQZ5q3kEvp4uTqSlDA false - - 2 - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09391 uniprotkb:A1YH68 intact:EBI-9134140|uniprotkb:Q2M788|uniprotkb:Q6BF32|uniprotkb:P76691|ensemblbacteria:AAT48182|ensemblbacteria:BAE77868 intact:EBI-10098044|ensemblbacteria:SUC45241|ensemblbacteria:SUC77857 psi-mi:glpg_ecoli(display_long)|uniprotkb:Intramembrane serine protease(gene name synonym)|uniprotkb:JW5687(locus name)|uniprotkb:b3424(locus name)|uniprotkb:glpG(gene name)|psi-mi:glpG(display_short) psi-mi:a1yh68_prost(display_long)|uniprotkb:tatA(gene name)|psi-mi:tatA(display_short)|uniprotkb:NCTC12257_03922(orf name) psi-mi:"MI:0415"(enzymatic study) Arutyunova et al. (2014) imex:IM-23751|pubmed:25009246 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:588(prost)|taxid:588(Providencia stuartii) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-10098071|imex:IM-23751-2 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_026220.1|refseq:WP_000928723.1|dip:DIP-9796N|ensemblbacteria:AAT48182(transcript)|ensemblbacteria:b3424(gene)|ensemblbacteria:BAE77868(gene)|ensemblbacteria:BAE77868(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0042802"(identical protein binding)|interpro:IPR022732|interpro:IPR022764|interpro:IPR023662|interpro:IPR035952|interpro:IPR038236|rcsb pdb:2IC8|rcsb pdb:2IRV|rcsb pdb:2LEP|rcsb pdb:2NRF|rcsb pdb:2O7L|rcsb pdb:2XOV|rcsb pdb:2XOW|rcsb pdb:2XTU|rcsb pdb:2XTV|rcsb pdb:3B44|rcsb pdb:3B45|rcsb pdb:3TXT|rcsb pdb:3UBB|rcsb pdb:3ZMH|rcsb pdb:3ZMI|rcsb pdb:3ZMJ|rcsb pdb:3ZOT|rcsb pdb:4H1D|rcsb pdb:4HDD|rcsb pdb:4NJN|rcsb pdb:4NJP|rcsb pdb:5F5B|rcsb pdb:5F5D|rcsb pdb:5F5G|rcsb pdb:5F5J|rcsb pdb:5F5K|rcsb pdb:5MT6|rcsb pdb:5MT7|rcsb pdb:5MT8|rcsb pdb:6PJ4|rcsb pdb:6PJ5|rcsb pdb:6PJ7|rcsb pdb:6PJ8|rcsb pdb:6PJ9|rcsb pdb:6PJA|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|rcsb pdb:6VJ8|rcsb pdb:6VJ9|rcsb pdb:6XRO|rcsb pdb:6XRP|rcsb pdb:3ZEB refseq:WP_004924718.1|ensemblbacteria:NCTC11800_03651(gene)|ensemblbacteria:NCTC12257_03922(gene)|ensemblbacteria:SUC45241(transcript)|ensemblbacteria:SUC77857(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0033281"(TAT protein transport complex)|go:"GO:0043953"(protein transport by the Tat complex)|interpro:IPR003369(Bacterial sec-independent translocation protein mttA/Hcf106)|interpro:IPR006312(Twin-arginine translocation protein TatA/E)|dip:DIP-60799N - - - figure legend:f1b f1c t1 sf1 f4e sf4b|comment:For all three rhomboids, we observed a loss of activity in the presence of DM, at conditions where the protein exists as a monomer. For AarA, purified in DDM, only 50% of activity was observed in DM reaction buffer, consistent with the gel filtration results, showing only partial dissociation. A full loss of activity for AarA was observed only when DM was used in both Ni-NTA purification and the activity assay.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/29 2015/01/29 rogid:9oSV7b6N1B4CKLgucotWxJlZigU83333 rogid:PkODM+LJUIm2icak0UjYA99sezc588 intact-crc:A9C561DE92ED952E|rigid:JgoYUB9Hj0t0B6KK7OhAxe8xY2U false - - 2 - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0113"(western blot) uniprotkb:P46116 uniprotkb:A1YH68 intact:EBI-10098058 intact:EBI-10098044|ensemblbacteria:SUC45241|ensemblbacteria:SUC77857 psi-mi:aara_prost(display_long)|uniprotkb:aarA(gene name)|psi-mi:aarA(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym) psi-mi:a1yh68_prost(display_long)|uniprotkb:tatA(gene name)|psi-mi:tatA(display_short)|uniprotkb:NCTC12257_03922(orf name) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Arutyunova et al. (2014) imex:IM-23751|pubmed:25009246 taxid:588(prost)|taxid:588(Providencia stuartii) taxid:588(prost)|taxid:588(Providencia stuartii) psi-mi:"MI:0194"(cleavage reaction) psi-mi:"MI:0471"(MINT) intact:EBI-10098100|imex:IM-23751-4 - - psi-mi:"MI:0501"(enzyme) psi-mi:"MI:0502"(enzyme target) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_004917931.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022764|interpro:IPR035952|dip:DIP-60798N refseq:WP_004924718.1|ensemblbacteria:NCTC11800_03651(gene)|ensemblbacteria:NCTC12257_03922(gene)|ensemblbacteria:SUC45241(transcript)|ensemblbacteria:SUC77857(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0033281"(TAT protein transport complex)|go:"GO:0043953"(protein transport by the Tat complex)|interpro:IPR003369(Bacterial sec-independent translocation protein mttA/Hcf106)|interpro:IPR006312(Twin-arginine translocation protein TatA/E)|dip:DIP-60799N - - - figure legend:f2b f2c t2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/29 2015/02/19 rogid:rMLMMVi9OcU6ksCBsNOREGL4uPA588 rogid:PkODM+LJUIm2icak0UjYA99sezc588 intact-crc:A99758301D1EEA7B|rigid:/+Vemi0U1dJHjv9zZkP55kBw0dA false mutation disrupting interaction:105-105 yellow fluorescent protein tag:c-c|cyanine label:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P44783 uniprotkb:P44783 intact:EBI-10098079|ensemblbacteria:AAC22277 intact:EBI-10098079|ensemblbacteria:AAC22277 psi-mi:glpg_haein(display_long)|uniprotkb:glpG(gene name)|psi-mi:glpG(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym)|uniprotkb:HI_0618(locus name) psi-mi:glpg_haein(display_long)|uniprotkb:glpG(gene name)|psi-mi:glpG(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym)|uniprotkb:HI_0618(locus name) psi-mi:"MI:0071"(molecular sieving) Arutyunova et al. (2014) imex:IM-23751|pubmed:25009246 taxid:71421(haein)|taxid:71421(Haemophilus influenzae) taxid:71421(haein)|taxid:71421(Haemophilus influenzae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10098249|imex:IM-23751-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022764|rcsb pdb:2NR9|rcsb pdb:3ODJ|refseq:NP_438776.1|interpro:IPR035952|refseq:WP_005648561.1|ensemblbacteria:AAC22277(transcript)|ensemblbacteria:HI_0618(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) interpro:IPR022764|rcsb pdb:2NR9|rcsb pdb:3ODJ|refseq:NP_438776.1|interpro:IPR035952|refseq:WP_005648561.1|ensemblbacteria:AAC22277(transcript)|ensemblbacteria:HI_0618(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) - - - figure legend:f4a sf5a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/29 2015/01/29 rogid:5L9JHN5FCD3YnHhk9cGMFtjt9pQ71421 rogid:5L9JHN5FCD3YnHhk9cGMFtjt9pQ71421 intact-crc:C073C2DF2CE44E16|rigid:vMBuoEb6SY91N77186jCW9VB46E false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P46116 uniprotkb:P46116 intact:EBI-10098058 intact:EBI-10098058 psi-mi:aara_prost(display_long)|uniprotkb:aarA(gene name)|psi-mi:aarA(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym) psi-mi:aara_prost(display_long)|uniprotkb:aarA(gene name)|psi-mi:aarA(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Arutyunova et al. (2014) imex:IM-23751|pubmed:25009246 taxid:588(prost)|taxid:588(Providencia stuartii) taxid:588(prost)|taxid:588(Providencia stuartii) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10098235|imex:IM-23751-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:WP_004917931.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022764|interpro:IPR035952|dip:DIP-60798N refseq:WP_004917931.1|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR022764|interpro:IPR035952|dip:DIP-60798N - - - figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/29 2015/01/29 rogid:rMLMMVi9OcU6ksCBsNOREGL4uPA588 rogid:rMLMMVi9OcU6ksCBsNOREGL4uPA588 intact-crc:66A1E3F9AC4D062C|rigid:Mh5YADRvE8YGQn9vAHKv3RyV9LA false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P09391 uniprotkb:P09391 intact:EBI-9134140|uniprotkb:Q2M788|uniprotkb:Q6BF32|uniprotkb:P76691|ensemblbacteria:AAT48182|ensemblbacteria:BAE77868 intact:EBI-9134140|uniprotkb:Q2M788|uniprotkb:Q6BF32|uniprotkb:P76691|ensemblbacteria:AAT48182|ensemblbacteria:BAE77868 psi-mi:glpg_ecoli(display_long)|uniprotkb:Intramembrane serine protease(gene name synonym)|uniprotkb:JW5687(locus name)|uniprotkb:b3424(locus name)|uniprotkb:glpG(gene name)|psi-mi:glpG(display_short) psi-mi:glpg_ecoli(display_long)|uniprotkb:Intramembrane serine protease(gene name synonym)|uniprotkb:JW5687(locus name)|uniprotkb:b3424(locus name)|uniprotkb:glpG(gene name)|psi-mi:glpG(display_short) psi-mi:"MI:0071"(molecular sieving) Arutyunova et al. (2014) imex:IM-23751|pubmed:25009246 taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10098238|imex:IM-23751-6 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:YP_026220.1|refseq:WP_000928723.1|dip:DIP-9796N|ensemblbacteria:AAT48182(transcript)|ensemblbacteria:b3424(gene)|ensemblbacteria:BAE77868(gene)|ensemblbacteria:BAE77868(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0042802"(identical protein binding)|interpro:IPR022732|interpro:IPR022764|interpro:IPR023662|interpro:IPR035952|interpro:IPR038236|rcsb pdb:2IC8|rcsb pdb:2IRV|rcsb pdb:2LEP|rcsb pdb:2NRF|rcsb pdb:2O7L|rcsb pdb:2XOV|rcsb pdb:2XOW|rcsb pdb:2XTU|rcsb pdb:2XTV|rcsb pdb:3B44|rcsb pdb:3B45|rcsb pdb:3TXT|rcsb pdb:3UBB|rcsb pdb:3ZMH|rcsb pdb:3ZMI|rcsb pdb:3ZMJ|rcsb pdb:3ZOT|rcsb pdb:4H1D|rcsb pdb:4HDD|rcsb pdb:4NJN|rcsb pdb:4NJP|rcsb pdb:5F5B|rcsb pdb:5F5D|rcsb pdb:5F5G|rcsb pdb:5F5J|rcsb pdb:5F5K|rcsb pdb:5MT6|rcsb pdb:5MT7|rcsb pdb:5MT8|rcsb pdb:6PJ4|rcsb pdb:6PJ5|rcsb pdb:6PJ7|rcsb pdb:6PJ8|rcsb pdb:6PJ9|rcsb pdb:6PJA|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|rcsb pdb:6VJ8|rcsb pdb:6VJ9|rcsb pdb:6XRO|rcsb pdb:6XRP|rcsb pdb:3ZEB refseq:YP_026220.1|refseq:WP_000928723.1|dip:DIP-9796N|ensemblbacteria:AAT48182(transcript)|ensemblbacteria:b3424(gene)|ensemblbacteria:BAE77868(gene)|ensemblbacteria:BAE77868(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0042802"(identical protein binding)|interpro:IPR022732|interpro:IPR022764|interpro:IPR023662|interpro:IPR035952|interpro:IPR038236|rcsb pdb:2IC8|rcsb pdb:2IRV|rcsb pdb:2LEP|rcsb pdb:2NRF|rcsb pdb:2O7L|rcsb pdb:2XOV|rcsb pdb:2XOW|rcsb pdb:2XTU|rcsb pdb:2XTV|rcsb pdb:3B44|rcsb pdb:3B45|rcsb pdb:3TXT|rcsb pdb:3UBB|rcsb pdb:3ZMH|rcsb pdb:3ZMI|rcsb pdb:3ZMJ|rcsb pdb:3ZOT|rcsb pdb:4H1D|rcsb pdb:4HDD|rcsb pdb:4NJN|rcsb pdb:4NJP|rcsb pdb:5F5B|rcsb pdb:5F5D|rcsb pdb:5F5G|rcsb pdb:5F5J|rcsb pdb:5F5K|rcsb pdb:5MT6|rcsb pdb:5MT7|rcsb pdb:5MT8|rcsb pdb:6PJ4|rcsb pdb:6PJ5|rcsb pdb:6PJ7|rcsb pdb:6PJ8|rcsb pdb:6PJ9|rcsb pdb:6PJA|rcsb pdb:6PJP|rcsb pdb:6PJQ|rcsb pdb:6PJR|rcsb pdb:6PJU|rcsb pdb:6VJ8|rcsb pdb:6VJ9|rcsb pdb:6XRO|rcsb pdb:6XRP|rcsb pdb:3ZEB - - - figure legend:f4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/29 2015/01/29 rogid:9oSV7b6N1B4CKLgucotWxJlZigU83333 rogid:9oSV7b6N1B4CKLgucotWxJlZigU83333 intact-crc:66A053F9AC4D062C|rigid:O6Jb1pi5vGsSRrJ74sHTrsCT9QE false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P44783 uniprotkb:P44783 intact:EBI-10098079|ensemblbacteria:AAC22277 intact:EBI-10098079|ensemblbacteria:AAC22277 psi-mi:glpg_haein(display_long)|uniprotkb:glpG(gene name)|psi-mi:glpG(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym)|uniprotkb:HI_0618(locus name) psi-mi:glpg_haein(display_long)|uniprotkb:glpG(gene name)|psi-mi:glpG(display_short)|uniprotkb:Intramembrane serine protease(gene name synonym)|uniprotkb:HI_0618(locus name) psi-mi:"MI:0016"(circular dichroism) Arutyunova et al. (2014) imex:IM-23751|pubmed:25009246 taxid:71421(haein)|taxid:71421(Haemophilus influenzae) taxid:71421(haein)|taxid:71421(Haemophilus influenzae) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-10098265|imex:IM-23751-8 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR022764|rcsb pdb:2NR9|rcsb pdb:3ODJ|refseq:NP_438776.1|interpro:IPR035952|refseq:WP_005648561.1|ensemblbacteria:AAC22277(transcript)|ensemblbacteria:HI_0618(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) interpro:IPR022764|rcsb pdb:2NR9|rcsb pdb:3ODJ|refseq:NP_438776.1|interpro:IPR035952|refseq:WP_005648561.1|ensemblbacteria:AAC22277(transcript)|ensemblbacteria:HI_0618(gene)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding) - - - figure legend:sf5c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2015/01/29 2015/02/19 rogid:5L9JHN5FCD3YnHhk9cGMFtjt9pQ71421 rogid:5L9JHN5FCD3YnHhk9cGMFtjt9pQ71421 intact-crc:377FD919B37D9A7C|rigid:vMBuoEb6SY91N77186jCW9VB46E false - - 2 0 psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant)